The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3

Title: The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3
Creator: Mautsa, Nicodemus, Prinsloo, Earl, Tastan Bishop, Özlem, Blatch, Gregory L
Date: 2011
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/148082
Identifier: vital:38708
Identifier: DOI: 10.1002/jmr.1111
Description: The protein inhibitor of activated signal transducer and activator of transcription 3 (PIAS3) regulates the transcriptional activity of signal transducer and activator of transcription 3 (STAT3) which regulates transcription of genes involved in cell growth, proliferation and apoptosis. The conserved proline, isoleucine, asparagine, isoleucine, threonine (PINIT) domain of PIAS3 is thought to promote STAT3–PIAS3 interaction.
Format: 9 pages, pdf
Language: English
Relation: Journal of Molecular Recognition, Mautsa, N., Prinsloo, E., Bishop, Ö.T. and Blatch, G.L., 2011. The PINIT domain of PIAS3: structure‐function analysis of its interaction with STAT3. Journal of Molecular Recognition, 24(5), pp.795-803., Journal of Molecular Recognition volume 24 number 5 795 803 June 2011 1099-1352
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Wiley Online Library Terms of Use statement (https://onlinelibrary.wiley.com/terms-and-conditions)

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Prinsloo, Earl (Dr)

Tastan Bishop, Ozlem (Prof)

Blatch, Gregory Lloyd (Prof)

RU Research Unit in Bioinformatics (RUBi)

SDG 03. Good Health and Well-Being

RU Department of Biochemistry, Microbiology and Bioinformatics

SDG 09. Industry, Innovation and Infrastructure

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