Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study

Title: Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study
Creator: Nyamai, Dorothy Wavinya, Tastan Bishop, Özlem
Date: 2018
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/148368
Identifier: vital:38733
Identifier: DOI: 10.1101/440891
Description: Treatment of parasitic diseases has been challenging due to evolution of drug resistant parasites, and thus there is need to identify new class of drugs and drug targets. Protein translation is important for survival of malarial parasite, Plasmodium, and the pathway is present in all of its life cycle stages. Aminoacyl tRNA synthetases are primary enzymes in protein translation as they catalyse amino acid addition to the cognate tRNA. This study sought to understand differences between Plasmodium and human aminoacyl tRNA synthetases through bioinformatics analysis.
Format: pdf
Language: English
Relation: Malaria journal, Nyamai, D.W. and Bishop, Ö.T., 2019. Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study. Malaria journal, 18(1), p.34., Malaria journal volume 18 number 1 p.34 2018 1475-2875
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the BioMed Central Limited Terms and Conditions statement (https://www.biomedcentral.com/terms-and-conditions)

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Tastan Bishop, Ozlem (Prof)

RU Research Unit in Bioinformatics (RUBi)

SDG 03. Good Health and Well-Being

RU Department of Biochemistry, Microbiology and Bioinformatics

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