- Title
- Hop/STIP1 depletion alters nuclear structure via depletion of nuclear structural protein emerin:
- Creator
- Kituyi, Sarah N, Edkins, Adrienne L
- Date
- 2018
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/164435
- Identifier
- vital:41118
- Identifier
- https://doi.org/10.1016/j.bbrc.2018.11.073
- Description
- Hop/STIP1 is a co-chaperone of Hsp70 and Hsp90 that regulates a number of cell biology processes via interactions with cellular proteins. Here we report a new relationship between Hop and the nuclear structural protein emerin in maintenance of nuclear morphology. Depletion or overexpression of Hop resulted in the reduction of emerin protein levels via proteasomal and lysosomal pathways.
- Format
- 7 pages, pdf
- Language
- English
- Relation
- Biochemical and biophysical research communications, Kituyi, S.N. and Edkins, A.L., 2018. Hop/STIP1 depletion alters nuclear structure via depletion of nuclear structural protein emerin. Biochemical and biophysical research communications, 507(1-4), pp.503-509, Biochemical and biophysical research communications volume 507 number 1-4 503 509 December 2018 0006-291X
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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