- Title
- Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay:
- Creator
- de la Mare, Jo-Anne, Sterrenberg, Jason N, Sukhthankar, Mugdha G, Chiwakata, Maynard T, Beukes, Denzil R, Blatch, Gregory L, Edkins, Adrienne L
- Date
- 2013
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/165184
- Identifier
- vital:41216
- Identifier
- DOI: 10.1186/1475-2867-13-39
- Description
- The cancer stem cell (CSC) theory proposes that tumours arise from and are sustained by a subpopulation of cells with both cancer and stem cell properties. One of the key hallmarks of CSCs is the ability to grow anchorage-independently under serum-free culture conditions resulting in the formation of tumourspheres. It has further been reported that these cells are resistant to traditional chemotherapeutic agents.
- Format
- 15 pages, pdf
- Language
- English
- Relation
- Cancer cell international, de la Mare, J.A., Sterrenberg, J.N., Sukhthankar, M.G., Chiwakata, M.T., Beukes, D.R., Blatch, G.L. and Edkins, A.L., 2013. Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay. Cancer cell international, 13(1), pp.1-14, Cancer cell international volume 13 number 1 1 14 May 2013 1475-2867
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the SpringerNature Statement (https://www.biomedcentral.com/)
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Beukes, Denzil Ronwynne (Prof)
De la Mare, Jo-Anne (Dr)
Edkins, Adrienne Lesley (Associate Prof)
Blatch, Gregory Lloyd (Prof)
RU Department of Pharmacy
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 03. Good Health and Well-Being
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