- Title
- Enhanced photodynamic antimicrobial activity of surface modified SiNPs doped with zinc (II) phthalocyanines: The effect of antimicrobial ampicillin and extra charges from a sultone
- Creator
- Magadla, Aviwe, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2020
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/186034
- Identifier
- vital:44457
- Identifier
- xlink:href="https://doi.org/10.1016/j.pdpdt.2020.101996"
- Description
- 1-(2-Methoxyethyl) piperidine sustituted Zn phthalocyanine complex (2) is synthesised and quartenised (3). These complexes are loaded into silica nanoparticles (SiNPs) that are futher surface modified with ampicillin and 1.3-propanesultone. The photophysical and photochemical properties of the complexes and their doped conjugates were investigated in dimethylsulfoxide. The cationic complex (3) is used for photodynamic antimicrobial activity. Log reduction values of above 9 are obtained towards the photoiactivation of Staphyloccocus aureus.
- Format
- computer, online resource, application/pdf, 1 online resource (11 pages), pdf
- Publisher
- Elsevier
- Language
- English
- Relation
- Photodiagnosis and Photodynamic Therapy, Magadla, A. and Nyokong, T., 2020. Enhanced photodynamic antimicrobial activity of surface modified SiNPs doped with zinc (II) phthalocyanines: The effect of antimicrobial ampicillin and extra charges from a sultone. Photodiagnosis and Photodynamic Therapy, 32, p.101996, Photodiagnosis and Photodynamic Therapy volume 32 p. 101996 2020 1572-1000
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
- Rights
- Closed Access
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details | SOURCE1 | Enhanced photodynamic antimicrobial activity of surface modified.pdf | 822 KB | Adobe Acrobat PDF | View Details |