- Title
- A novel axially palladium (II)-Schiff base complex substituted silicon (IV) phthalocyanine
- Creator
- Sen, Pinar, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2019
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/186813
- Identifier
- vital:44536
- Identifier
- xlink:href="https://doi.org/10.1016/j.poly.2019.114135"
- Description
- In this study, a novel silicon(IV) phthalocyanine is reported for the first time as a phthalocyanine derivative bearing axially a palladium(II)-Schiff base complex. The photophysical and photochemical properties of the new Si(IV)Pc, such as absorption, fluorescence, singlet oxygen quantum yields, triplet state quantum yields and exited state lifetimes were measured in DMSO. The new silicon phthalocyanine displayed very low fluorescence, showing efficient intersystem crossing resulting in high triplet and high singlet oxygen quantum yields in DMSO. When compared with the unsubstituted SiPcCl2, the singlet oxygen quantum yield value (UD = 0.47) in relation to the triplet quantum yield (UT = 0.82), which is an important determinant for PDT applications, increased. The photodynamic antimicrobial chemotherapy activity (PACT) of new Si(IV)Pc towards Staphylococcus aureus was determined in comparison to the unsubstituted SiPcCl2. The results of the photodynamic antimicrobial effect study demonstrated that the Pd(II) complex substituted SiPc (5) possesses excellent photodynamic activity with a reduction percentage value of 99.94% and a log red value of 3.26.
- Format
- computer, online resource, application/pdf, 1 online resource (9 pages), pdf
- Publisher
- Elsevier
- Language
- English
- Relation
- Polyhedron, Sen, P. and Nyokong, T., 2019. A novel axially palladium (II)-Schiff base complex substituted silicon (IV) phthalocyanine: Synthesis, characterization, photophysicochemical properties and photodynamic antimicrobial chemotherapy activity against Staphylococcus aureus. Polyhedron, 173, p.114135, Polyhedron volume 173 p. 114135 2019 0277-5387
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
- Rights
- Closed Access
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details | SOURCE1 | A novel axially palladium (II)-Schiff base complex substituted silicon (IV) phthalocyanine.pdf | 778 KB | Adobe Acrobat PDF | View Details |