- Title
- Photophysicochemical behavior and antimicrobial activity of dihydroxosilicon tris (diaquaplatinum) octacarboxyphthalocyanine
- Creator
- Managa, Muthumuni, Idowu, Mopelola A, Antunes, Edith M, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2014
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/241527
- Identifier
- vital:50947
- Identifier
- xlink:href="https://doi.org/10.1016/j.saa.2014.01.087"
- Description
- Platination of dihydroxosilicon octacarboxyphthalocyanine (OH)2SiOCPc was successfully carried out to give dihydroxosilicon tris(diaquaplatinum)octacarboxyphthalocyanine (OH)2SiOCPc(Pt)3 conjugate. Slight blue shifting of the absorption spectrum of (OH)2SiOCPc(Pt)3 was observed on conjugation with platinum. Comparative photophysicochemical behavior and antimicrobial photo-activities of (OH)2SiOCPc(Pt)3 conjugate with (OH)2SiOCPc or Pt nanoparticles revealed that the heavy atom, Pt on the periphery of the phthalocyanine significantly enhanced its singlet oxygen generation with a quantum yield of 0.56 obtained for the (OH)2SiOCPc(Pt)3 conjugate. The (OH)2SiOCPc(Pt)3 conjugate showed highest antimicrobial activity towards Candida albicans and Escherichia coli compared to (OH)2SiOCPc and Pt nanoparticles alone under illumination.
- Format
- computer, online resource, application/pdf, 1 online resource (7 pages), pdf
- Publisher
- Elsevier
- Language
- English
- Relation
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Managa, M., Idowu, M.A., Antunes, E. and Nyokong, T., 2014. Photophysicochemical behavior and antimicrobial activity of dihydroxosilicon tris (diaquaplatinum) octacarboxyphthalocyanine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 125, pp.147-153, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy volume 125 p. 147 2014 1873-3557
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
- Rights
- Closed Access
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Antunes, Edith Martins (Dr)
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Photophysicochemical behavior and antimicrobial activity.pdf | 844 KB | Adobe Acrobat PDF | View Details Download |