- Title
- Photophysicochemical properties and TD-DFT calculations of a novel terminal alkyne substituted metal free phthalocyanine
- Creator
- Yilmaz, Yusuf, Mack, John, Sönmez, Mehmet, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2014
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/241562
- Identifier
- vital:50950
- Identifier
- xlink:href="https://doi.org/10.1142/S1088424613501241"
- Description
- The synthesis of a novel free base tetrakis(prop-2-ynyloxy)phthalocyanine (2) is described, along with its characterization by IR, UV-visible absorption, and 1H NMR spectroscopy and mass spectrometry. The compound exhibited good solubility in a wide range of organic solvents and no significant aggregation was observed over a wide concentration range. The values for the singlet oxygen (ΦΔ), photodegradation, fluorescence (ΦF) and triplet state quantum yields and the fluorescence and triplet state lifetimes are reported. A relatively high ΦΔ value of 0.46 was obtained in DMSO. The ability to carry out "click" chemistry at the ligand periphery enhances the potential utility of 2 for use in bioconjugates in photodynamic therapy (PDT). A moderately high ΦF value of 0.18 is observed for emission in the therapeutic window in the near-IR region, which suggests that it may also be possible to determine the level of localization of 2 in tumor cells through bioimaging.
- Format
- computer, online resource, application/pdf, 1 online resource (8 pages), pdf
- Publisher
- World Scientific Publishing
- Language
- English
- Relation
- Journal of Porphyrins and Phthalocyanines, Yılmaz, Y., Mack, J., Sönmez, M. and Nyokong, T., 2014. Photophysicochemical properties and TD-DFT calculations of a novel terminal alkyne substituted metal free phthalocyanine. Journal of Porphyrins and Phthalocyanines, 18(03), pp.251-258, Journal of Porphyrins and Phthalocyanines volume 18 number 03 p. 251 2014 1099-1409
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the World Scientific Copyright and Permissions Statement (https://0-www.worldscientific.com.wam.seals.ac.za/page/permissions)
- Rights
- Closed Access
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Collections
Mack, John (Associate Prof)
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Photophysicochemical properties and TD-DFT calculations.pdf | 712 KB | Adobe Acrobat PDF | View Details Download |