- Title
- Metallophthalocyanine Based Carbon Paste Electrodes for the Determination of 2′, 3′‐Dideoxyinosine
- Creator
- Ozoemena, Kenneth I, Stefan-van Staden, Raluca-Ioana, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2009
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/263430
- Identifier
- vital:53627
- Identifier
- xlink:href="https://doi.org/10.1002/elan.200904581"
- Description
- Novel electrochemical sensors based on carbon paste impregnated with metallopthalocyanine (MPc, M=Co, Fe) complexes, have been constructed for the assay of anti-HIV drug 2′,3′-dideoxyinosine (didanosine, DDI). Both modified electrodes showed electrocatalytic activity towards the oxidation of dideoxyinosine in phosphate buffer pH 7.4 with a working concentration range of 10−6–10−4 mol/L and a detection limit of 10−7 mol/L magnitude order. The sensor proved to be highly reliable for the assay of the purity of DDI - raw material as well as for the uniformity content test of Videx tablets.
- Format
- computer, online resource, application/pdf, 1 online resource (4 pages), pdf
- Publisher
- Wiley Library Online
- Language
- English
- Relation
- An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, Ozoemena, K.I., Stefan‐van Staden, R.I. and Nyokong, T., 2009. Metallophthalocyanine Based Carbon Paste Electrodes for the Determination of 2′, 3′‐Dideoxyinosine. Electroanalysis: An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, 21(14), pp.1651-1654, An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis volume 21 number 14 p. 1651 2009 1521-4109
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Wiley Library Online Terms of Use Statement (https://onlinelibrary.wiley.com/terms-and-conditions)
- Rights
- Closed Access
- Hits: 601
- Visitors: 693
- Downloads: 93
Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Metallophthalocyanine Based Carbon Paste Electrodes for the Determination.pdf | 644 KB | Adobe Acrobat PDF | View Details Download |