- Title
- Photophysical, photochemical and bovine serum albumin binding studies on water-soluble gallium (III) phthalocyanine derivatives
- Creator
- Ogunsipe, Abimbola, Nyokong, Tebello, Durmus, Mahmut
- Subject
- To be catalogued
- Date
- 2007
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/271239
- Identifier
- vital:54524
- Identifier
- xlink:href="https://doi.org/10.1142/S1088424607000746"
- Description
- Spectral, photophysical, photochemical and bovine serum albumin binding studies on some gallium(III) derivatives - {1,(4)-(tetrapyridyloxyphthalocyaninato)gallium(III), (αGaPc); 2,(3)-(tetrapyridyloxyphthalocyaninato)gallium(III), (βGaPc); and their quaternized derivatives: QαGaPc and QβGaPc)} are hereby presented. β-Substituted complexes are more fluorescent, but show lower tendencies to undergo intersystem crossing than the α-substituted, as judged by their fluorescence and triplet quantum yield values. The quaternized derivatives (QGaPc) are water-soluble and non-aggregated, which makes them potential photosensitizers of choice for photodynamic therapy applications; these amphiphilic compounds also bind strongly to bovine serum albumin in 1:1 stoichiometries, and with binding constants (Kb) in the order of 106 M−1.
- Format
- computer, online resource, application/pdf, 1 online resource (11 pages), pdf
- Publisher
- World Scientific Publishing
- Language
- English
- Relation
- Journal of Porphyrins and Phthalocyanines, Ogunsipe, A., Nyokong, T. and Durmuş, M., 2007. Photophysical, photochemical and bovine serum albumin binding studies on water-soluble gallium (III) phthalocyanine derivatives. Journal of Porphyrins and Phthalocyanines, 11(09), pp.635-644, Journal of Porphyrins and Phthalocyanines volume 11 number 09 p. 635 2007 1099-1409
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the World Scientific Copyright and Permissions Statement (https://0-www.worldscientific.com.wam.seals.ac.za/page/permissions)
- Rights
- Closed Access
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Photophysical, photochemical and bovine serum albumin binding studies on water-soluble gallium.pdf | 822 KB | Adobe Acrobat PDF | View Details Download |