- Title
- Comparative bioavailability of some locally manufactured betamethasone valerate containing preparations
- Creator
- Meyer, Eric, Haigh, John M, Kanfer, Isadore
- Date
- 1983
- Type
- Article
- Identifier
- vital:6399
- Identifier
- http://hdl.handle.net/10962/d1006326
- Description
- The bioavailabilities of three locally manufactured proprietary betamethasone- 17-valerate containing creams and ointments were compared by measuring their abilities to cause blanching of human skin after topical application. The preparations studied were Betnovate Cream and Ointment, Celestoderm-V Cream and Ointment and Persivate Cream and Ointment. Celestoderm-V cream displayed a significantly superior blanching activity over both Betnovate and Persivate creams in' the occluded mode, whereas Persivate cream displayed a significantly superior blanching activity over both Betnovate and Celestoderm-V creams in the unoccluded mode. Persivate ointment was found to produce a significantly superior blanching activity over Betnovate and Celestoderm-V ointments in both the occluded and unoccluded modes of application.
- Format
- 3 pages, pdf
- Language
- English
- Relation
- Meyer, E. and Haigh, J.M. and Kanfer, I. (1983) Comparative bioavailability of some locally manufactured betamethasone valerate containing preparations. South African Pharmaceutical Journal, 50 . pp. 443-447.
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