Antiviral drug discovery: preparing for the next pandemic

Title: Antiviral drug discovery: preparing for the next pandemic
Creator: Adamson, Catherine S, Chibale, Kelly, Goss, Rebecca J M, Jaspars, Marcel, Newman, David J, Dorrington, Rosemary A
Date: 2021
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/177499
Identifier: vital:42827
Identifier: DOI: 10.1039/d0cs01118e
Description: Clinically approved antiviral drugs are currently available for only 10 of the more than 220 viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need for compounds that can be rapidly mobilised for the treatment of re-emerging or emerging viral diseases, while vaccine development is underway. We review the current status of antiviral therapies focusing on RNA viruses, highlighting strategies for antiviral drug discovery and discuss the challenges, solutions and options to accelerate drug discovery efforts.
Format: 9 pages, pdf
Language: English
Relation: Chemical Society Reviews, Adamson, C.S., Chibale, K., Goss, R.J., Jaspars, M., Newman, D.J. and Dorrington, R.A., 2021. Antiviral drug discovery: preparing for the next pandemic. Chemical Society Reviews. 50, pp. 3647-3655, Chemical Society Reviews volume 50 number 3647 3655 2021 1460-4744
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Royal Society of Chemistry Terms and Conditions Statement (https://0-www.rsc.org.wam.seals.ac.za/help-legal/)

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