- Title
- Biological activity of extracellular and intracellular polysaccharides from Pleurotus tuber-regium hybrid and mutant strains
- Creator
- Bamigboye, Comfort O, Oloke, Julius K, Dames, Joanna Felicity
- Date
- 2016
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/69056
- Identifier
- vital:29376
- Identifier
- http://pubs.sciepub.com/jfnr/4/7/2/
- Description
- Publisher version
- Description
- Pleurotus tuber-regium (Fr.) Singer (1951) is a unique sclerotium-forming edible and medicinal mushroom. Interestingly, both the sclerotium and mushroom are edible and are often used for curing various ailments. Previous studies have focused on the antimicrobial and antioxidant activity of the extracellular polysaccharide (EPS) from wild P. tuber-regium. There has been no report on the intracellular polysaccharide (IPS) of the wild mycelia, likewise there is very meager information on the improvement of the perceived potentials of P. tuber-regium. This research study analysed the EPS and IPS fractions of P. tuber-regium hybrid and mutant strains. The antimicrobial potential of the IPS and EPS fractions, their scavenging activity on 1, 1-diphenyl–2picryhydrazyl (DPPH) and Hydroxyl radicals were also determined. Both IPS and EPS fractions of P. tuber-regium hybrids and mutants showed increased DPPH and hydroxyl scavenging activity over the wild P. tuber-regium with an EC50 mostly 1 mg/ml. The antimicrobial activity of the IPS from a mutant strain had an IC50 of 15.6 mg/ml compared to the wild type (18.75 mg /ml). This study showed that selected mutant and hybrids of P. tuber-regium had increased radical scavenging activity indicating potentially increased biological activity that could offer increased benefit as a neutraceutical.
- Format
- 7 pages, pdf
- Publisher
- Science and Education Publishing
- Language
- English
- Relation
- Journal of Food and Nutrition Research, Bamigboye, C.O., Oloke, J.K. and Dames, J.F. (2016) “Biological Activity of Extracellular and Intracellular Polysaccharides from Pleurotus tuber-regium Hybrid and Mutant Strains.” Journal of Food and Nutrition Research, vol. 4 (7): 422-428. doi: 10.12691/jfnr-4-7-2, Journal of Food and Nutrition Research volume 4 number 7 422 428 2016 2333-1240
- Rights
- Science and Education Publishing
- Rights
- Use of this resource is governed by the terms and conditions of the Journal of Food and Nutrition Research
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Collections
Dames, Joanna Felicity (Prof)
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 15. Life On Land
SDG 03. Good Health and Well-Being
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