Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches:

Noundou, Xavier S; Musyoka, Thommas M; Moses, Vuyani; Ndinteh, Derek T; Mnkandhla, Dumisani; Hoppe, Heinrich C; Tastan Bishop, Özlem; Krause, Rui W M

Title: Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches:
Creator: Noundou, Xavier S, Musyoka, Thommas M, Moses, Vuyani, Ndinteh, Derek T, Mnkandhla, Dumisani, Hoppe, Heinrich C, Tastan Bishop, Özlem, Krause, Rui W M
Date: 2019
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/162975
Identifier: vital:41001
Identifier: https://0-doi.org.wam.seals.ac.za/10.1038/s41598-019-41403-x
Description: According to the 2018 report of the United Nations Programme on HIV/AIDS (UNAIDS), acquired immune deficiency syndrome (AIDS), a disease caused by the human immunodeficiency virus (HIV), remains a significant public health problem. The non-existence of a cure or effective vaccine for the disease and the associated emergence of resistant viral strains imply an urgent need for the discovery of novel anti-HIV drug candidates. The current study aimed to identify potential anti-retroviral compounds from Alchornea cordifolia.
Format: 10 pages, pdf
Language: English
Relation: Scientific reports, Siwe-Noundou, X., Musyoka, T.M., Moses, V., Ndinteh, D.T., Mnkandhla, D., Hoppe, H., Bishop, Ö.T. and Krause, R.W., 2019. Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches. Scientific reports, 9(1), pp.1-9, Scientific reports volume 9 number 1 1 9 March 2019 2045-2322
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Nature Terms and Conditions Statement (https://www.nature.com/info/terms-and-conditions)

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Tastan Bishop, Ozlem (Prof)

Krause, Rui Werner Maçedo (Prof)

RU Research Unit in Bioinformatics (RUBi)

Hoppe, Heinrich C (Prof)

RU Department of Biochemistry, Microbiology and Bioinformatics

SDG 03. Good Health and Well-Being

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