- Title
- Comparative structural bioinformatics analysis of Bacillus amyloliquefaciens chemotaxis proteins within Bacillus subtilis group
- Creator
- Yssel, Anna, Reva, Oleg, Tastan Bishop, Özlem
- Date
- 2011
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/123966
- Identifier
- vital:35521
- Identifier
- https://doi.10.1007/s00253-011-3582-y
- Description
- Chemotaxis is a process in which bacteria sense their chemical environment and move towards more favorable conditions. Since plant colonization by bacteria is a multifaceted process which requires a response to the complex chemical environment, a finely tuned and sensitive chemotaxis system is needed. Members of the Bacillus subtilis group including Bacillus amyloliquefaciens are industrially important, for example, as bio-pesticides. The group exhibits plant growth-promoting characteristics, with different specificity towards certain host plants. Therefore, we hypothesize that while the principal molecular mechanisms of bacterial chemotaxis may be conserved, the bacterial chemotaxis system may need an evolutionary tweaking to adapt it to specific requirements, particularly in the process of evolution of free-living soil organisms, towards plant colonization behaviour. To date, almost nothing is known about what parts of the chemotaxis proteins are subjected to positive amino acid substitutions, involved in adjusting the chemotaxis system of bacteria during speciation. In this novel study, positively selected and purified sites of chemotaxis proteins were calculated, and these residues were mapped onto homology models that were built for the chemotaxis proteins, in an attempt to understand the spatial evolution of the chemotaxis proteins. Various positively selected amino acids were identified in semi-conserved regions of the proteins away from the known active sites.
- Format
- 12 pages, pdf
- Language
- English
- Relation
- Applied microbiology and biotechnology, Yssel, A., Reva, O. and Bishop, O.T., 2011. Comparative structural bioinformatics analysis of Bacillus amyloliquefaciens chemotaxis proteins within Bacillus subtilis group. Applied microbiology and biotechnology, 92(5), pp.997-1008, Applied microbiology and biotechnology volume 92 number 5 997 1008 2011 0175-7598
- Rights
- Applied microbiology and biotechnology
- Rights
- Use of this resource is governed by the terms and conditions of the SpringerLink Terms on Use statement (https://link.springer.com/termsandconditions)
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Tastan Bishop, Ozlem (Prof)
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 03. Good Health and Well-Being
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