- Title
- Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties:
- Creator
- Gramni, Larusha, Vukea, Nyeleti, Chakraborty, Abir, Samson, William J, Dingle, Laura M K, Xulu, Bheki, de la Mare, Jo-Anne, Edkins, Adrienne L, Booysen, Irvin N
- Date
- 2019
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/163477
- Identifier
- vital:41041
- Identifier
- DOI: 10.1016/j.ica.2019.04.01
- Description
- In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques and the X-ray solid-state structures of 1 and Hurdpa have been attained.
- Format
- Language
- English
- Relation
- Inorganica Chimica Acta, Gramni, L., Vukea, N., Chakraborty, A., Samson, W.J., Dingle, L.M.K., Xulu, B., de la Mare, J.A., Edkins, A.L. and Booysen, I.N., 2019. Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties. Inorganica Chimica Acta, 492, pp.98-107, Inorganica Chimica Acta volume 492 number 98 107 June 2019 0020-1693
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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RU DST/NRF SARChI for Molecular and Cellular Biology of the Eukaryotic Stress Response
De la Mare, Jo-Anne (Dr)
Edkins, Adrienne Lesley (Associate Prof)
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 03. Good Health and Well-Being
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