Analysis of the anti-cancer activity of novel indigenous algal compounds in breast cancer: towards the development of a model for screening anti-cancer stem cell activity
- Authors: Lawson, Jessica Clair
- Date: 2010
- Subjects: Breast -- Cancer , Breast -- Cancer -- Chemotherapy , Breast -- Cancer -- Treatment , Red algae , Brown algae , Algae -- Biotechnology
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3925 , http://hdl.handle.net/10962/d1003984 , Breast -- Cancer , Breast -- Cancer -- Chemotherapy , Breast -- Cancer -- Treatment , Red algae , Brown algae , Algae -- Biotechnology
- Description: Breast cancer, the most common malignancy diagnosed in women, is one of the leading causes of death in women worldwide. In South Africa only 32% of women diagnosed with advanced breast cancer survive more than five years. The search for new chemotherapeutic agents capable of effectively treating breast cancer is therefore essential. Recent evidence supporting the cancer stem cell theory of cancer development for breast cancer challenges the current theories of cancer development and hence treatment. Cancer stem cells are a small subpopulation of tumour cells that possess properties of both cancer cells and stem cells and are believed to be the tumour-initiating population of many cancers. Cancer stem cells are inherently resistant to many chemotherapeutic agents and in this way have been associated with repopulation of tumours after chemotherapy. This phenomenon is proposed as a possible mechanism for cancer relapse after treatment. Cancer stem cells have also been implicated in metastasis, the major cause of mortality in cancer patients. Therefore, any treatment that is capable of targeting and removing breast cancer stem cells may have the theoretical potential to effectively treat breast cancer. However, there are currently no such treatments available for clinical use. We were provided access to a library of novel indigenous small molecules isolated from red and brown algae found off the Eastern Cape of South Africa. The aim of this project was to analyse the anti-cancer and anti-cancer stem cell properties of the compounds in this library and to identify „hit‟ compounds which could form the basis for future development into new anti-cancer drugs. Ten novel compounds of algal origin were tested for cytotoxicity, by determining their ability to inhibit the growth of MCF12A breast epithelial cells and MCF7 breast cancer cells using the colorimetric MTT [(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] cell proliferation assay. All but one of the compounds tested exhibited cytotoxicity towards the MCF7 cancer cell line, with IC50 values (the concentration of the compound that leads to a 50% inhibition in cell growth) of between 3 μM and 90 μM. The chemotherapeutic drug paclitaxel was used as a positive control. Four of the compounds (RUMB-001, RUMB-002, RUMB-007 and RUMB-010/saragaquinoic acid) were significantly more toxic to the MCF7 cancer cell line, than the „normal‟ MCF12A breast cells and were selected as priority compounds for further analyses. In addition, two other compounds were selected as priority compounds, one highly cytotoxic towards both MCF12A and MCF7 cell lines (RUMB-015) and one which was non toxic to either cell line (RUMB-017/018). Preliminary studies into the mechanism of cytotoxicity using Western blot analysis for poly (ADP-ribose) polymerase (PARP) cleavage and Hoechst 33342 immunostaining in MCF-7 cells were largely unsuccessful. The Hoechst 33342 immunostaining assay did provide tentative evidence that selected priority compounds were capable of inducing apoptosis, although these assays will need to be repeated using a less subjective assay to confirm the results. The priority compounds were subsequently investigated for their cytotoxic effect on the cancer stem cell-enriched side population in MCF7 cells. The ability of the priority compounds to selectively target the cancer stem cell containing side population was assessed using two complementary flow cytometry-based techniques – namely the Hoechst 33342-exclusion assay, and fluorescent immunostaining for the expression of the putative cancer stem cell marker, ABCG2+. The ABCG2+ staining assay was a novel technique developed during the course of this study. It remains to be fully validated, but it may provide a new and reliable way to identify and analyse cancer stem cell containing side population cells. The MCF7 cells were treated with the compounds and the proportion of putative cancer stem cells compared with the size of the population in untreated cells was assessed. Three compounds (RUMB-010, RUMB-015 and RUMB-017/018) capable of reducing the proportion of side population cells within the MCF7 cell line were identified. Taking these data together, we identified two potential „hit‟ compounds which should be prioritised for future research. These are compounds RUMB-010/sargaquinoic acid and RUMB-017/018. RUMB-010 is of interest as it was shown to target the putative cancer stem cell population, in addition to the bulk MCF7 tumour line, but was relatively less toxic to the „normal‟ MCF12A cell line. RUMB-017/018 is of interest due to the ability to selectively target the cancer stem cell enriched side population, while having little effect on the normal (MCF12A) or bulk tumour (MCF7) cell lines tested. These compounds will be important as „hit‟ compounds for drug development and as tool compounds to study cancer and cancer stem cell biology.
- Full Text:
- Date Issued: 2010
- Authors: Lawson, Jessica Clair
- Date: 2010
- Subjects: Breast -- Cancer , Breast -- Cancer -- Chemotherapy , Breast -- Cancer -- Treatment , Red algae , Brown algae , Algae -- Biotechnology
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3925 , http://hdl.handle.net/10962/d1003984 , Breast -- Cancer , Breast -- Cancer -- Chemotherapy , Breast -- Cancer -- Treatment , Red algae , Brown algae , Algae -- Biotechnology
- Description: Breast cancer, the most common malignancy diagnosed in women, is one of the leading causes of death in women worldwide. In South Africa only 32% of women diagnosed with advanced breast cancer survive more than five years. The search for new chemotherapeutic agents capable of effectively treating breast cancer is therefore essential. Recent evidence supporting the cancer stem cell theory of cancer development for breast cancer challenges the current theories of cancer development and hence treatment. Cancer stem cells are a small subpopulation of tumour cells that possess properties of both cancer cells and stem cells and are believed to be the tumour-initiating population of many cancers. Cancer stem cells are inherently resistant to many chemotherapeutic agents and in this way have been associated with repopulation of tumours after chemotherapy. This phenomenon is proposed as a possible mechanism for cancer relapse after treatment. Cancer stem cells have also been implicated in metastasis, the major cause of mortality in cancer patients. Therefore, any treatment that is capable of targeting and removing breast cancer stem cells may have the theoretical potential to effectively treat breast cancer. However, there are currently no such treatments available for clinical use. We were provided access to a library of novel indigenous small molecules isolated from red and brown algae found off the Eastern Cape of South Africa. The aim of this project was to analyse the anti-cancer and anti-cancer stem cell properties of the compounds in this library and to identify „hit‟ compounds which could form the basis for future development into new anti-cancer drugs. Ten novel compounds of algal origin were tested for cytotoxicity, by determining their ability to inhibit the growth of MCF12A breast epithelial cells and MCF7 breast cancer cells using the colorimetric MTT [(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] cell proliferation assay. All but one of the compounds tested exhibited cytotoxicity towards the MCF7 cancer cell line, with IC50 values (the concentration of the compound that leads to a 50% inhibition in cell growth) of between 3 μM and 90 μM. The chemotherapeutic drug paclitaxel was used as a positive control. Four of the compounds (RUMB-001, RUMB-002, RUMB-007 and RUMB-010/saragaquinoic acid) were significantly more toxic to the MCF7 cancer cell line, than the „normal‟ MCF12A breast cells and were selected as priority compounds for further analyses. In addition, two other compounds were selected as priority compounds, one highly cytotoxic towards both MCF12A and MCF7 cell lines (RUMB-015) and one which was non toxic to either cell line (RUMB-017/018). Preliminary studies into the mechanism of cytotoxicity using Western blot analysis for poly (ADP-ribose) polymerase (PARP) cleavage and Hoechst 33342 immunostaining in MCF-7 cells were largely unsuccessful. The Hoechst 33342 immunostaining assay did provide tentative evidence that selected priority compounds were capable of inducing apoptosis, although these assays will need to be repeated using a less subjective assay to confirm the results. The priority compounds were subsequently investigated for their cytotoxic effect on the cancer stem cell-enriched side population in MCF7 cells. The ability of the priority compounds to selectively target the cancer stem cell containing side population was assessed using two complementary flow cytometry-based techniques – namely the Hoechst 33342-exclusion assay, and fluorescent immunostaining for the expression of the putative cancer stem cell marker, ABCG2+. The ABCG2+ staining assay was a novel technique developed during the course of this study. It remains to be fully validated, but it may provide a new and reliable way to identify and analyse cancer stem cell containing side population cells. The MCF7 cells were treated with the compounds and the proportion of putative cancer stem cells compared with the size of the population in untreated cells was assessed. Three compounds (RUMB-010, RUMB-015 and RUMB-017/018) capable of reducing the proportion of side population cells within the MCF7 cell line were identified. Taking these data together, we identified two potential „hit‟ compounds which should be prioritised for future research. These are compounds RUMB-010/sargaquinoic acid and RUMB-017/018. RUMB-010 is of interest as it was shown to target the putative cancer stem cell population, in addition to the bulk MCF7 tumour line, but was relatively less toxic to the „normal‟ MCF12A cell line. RUMB-017/018 is of interest due to the ability to selectively target the cancer stem cell enriched side population, while having little effect on the normal (MCF12A) or bulk tumour (MCF7) cell lines tested. These compounds will be important as „hit‟ compounds for drug development and as tool compounds to study cancer and cancer stem cell biology.
- Full Text:
- Date Issued: 2010
Photophysical studies of 2, 6-dibrominated BODIPY dyes substituted with 4-benzyloxystyryl substituents
- Ngoy, Bokolombe Pitchou, Molupe, Nthabeleng, Harris, Jessica, Fomo, Gertrude, Mack, John, Nyokong, Tebello
- Authors: Ngoy, Bokolombe Pitchou , Molupe, Nthabeleng , Harris, Jessica , Fomo, Gertrude , Mack, John , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233068 , vital:50053 , xlink:href="https://doi.org/10.1142/S1088424617500420"
- Description: A series of novel 2,6-dibrominated BODIPY dyes with styryl groups at the 3,5-positions has been prepared, and their photophysical properties have been analyzed to assess their potential utility for use as photosensitizers in photodynamic therapy and in bioimaging.
- Full Text:
- Date Issued: 2017
- Authors: Ngoy, Bokolombe Pitchou , Molupe, Nthabeleng , Harris, Jessica , Fomo, Gertrude , Mack, John , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233068 , vital:50053 , xlink:href="https://doi.org/10.1142/S1088424617500420"
- Description: A series of novel 2,6-dibrominated BODIPY dyes with styryl groups at the 3,5-positions has been prepared, and their photophysical properties have been analyzed to assess their potential utility for use as photosensitizers in photodynamic therapy and in bioimaging.
- Full Text:
- Date Issued: 2017
Optical Limiting Properties of 3, 5-Dithienylenevinylene BODIPY Dyes at 532 nm
- Harris, Jessica, Gai, Lizhi, Kubheka, Gugu, Mack, John, Nyokong, Tebello, Shen, Zhen
- Authors: Harris, Jessica , Gai, Lizhi , Kubheka, Gugu , Mack, John , Nyokong, Tebello , Shen, Zhen
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189274 , vital:44833 , xlink:href="https://doi.org/10.1002/chem.201702503"
- Description: The optical limiting properties of a series of near infrared absorbing 3,5-dithienylenevinylene BODIPY (borondipyrromethene) dyes (1–3) that contain donor and acceptor moieties in their p-conjugation systems were studied by using the z-scan technique at 532 nm in the nanosecond pulse range. A strong reverse saturable absorption response was observed when the compounds are embedded into poly(bisphenol carbonate A) polymer thin films, which demonstrates that BODIPY dyes with this type of structure are suitable for use in optical limiting applications.
- Full Text:
- Date Issued: 2017
- Authors: Harris, Jessica , Gai, Lizhi , Kubheka, Gugu , Mack, John , Nyokong, Tebello , Shen, Zhen
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189274 , vital:44833 , xlink:href="https://doi.org/10.1002/chem.201702503"
- Description: The optical limiting properties of a series of near infrared absorbing 3,5-dithienylenevinylene BODIPY (borondipyrromethene) dyes (1–3) that contain donor and acceptor moieties in their p-conjugation systems were studied by using the z-scan technique at 532 nm in the nanosecond pulse range. A strong reverse saturable absorption response was observed when the compounds are embedded into poly(bisphenol carbonate A) polymer thin films, which demonstrates that BODIPY dyes with this type of structure are suitable for use in optical limiting applications.
- Full Text:
- Date Issued: 2017
Spectroscopic investigations and theoretical calculations of DABCO induced xanthene bridged self-assembled zinc (II) porphyrin dimer
- Xu, Li, Huang, Tingting, Liang, Xu, Mack, John, Harris, Jessica, Nyokong, Tebello, Li, Minzhi, Zhu, Weihua
- Authors: Xu, Li , Huang, Tingting , Liang, Xu , Mack, John , Harris, Jessica , Nyokong, Tebello , Li, Minzhi , Zhu, Weihua
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/240732 , vital:50866 , xlink:href="https://doi.org/10.1142/S1088424616500231"
- Description: An in-depth study of the electronic structure of a 1,4-diazabicyclo[2.2.2]octane (DABCO) induced molecular self-assembled xanthene-bridged and amide-bonded porphyrin dimer is reported. Density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations are used to identify trends in the optical spectroscopic properties. B3LYP geometry optimization predicts the formation of an almost perfectly eclipsed structure with respect to the two porphyrin rings with the analogous pyrrole nitrogens separated by 7.7–8.1 Å. The observed distinctive derivative-shaped band morphology of the pseudo-Faraday-A11 terms in the MCD spectra has been used to identify the main electronic Q and B-bands and to validate the TD-DFT calculations. The absence of a discernible splitting of the redox steps or a quenching of the fluorescence demonstrates that there is no significant exciton coupling between the two porphyrin rings.
- Full Text:
- Date Issued: 2016
- Authors: Xu, Li , Huang, Tingting , Liang, Xu , Mack, John , Harris, Jessica , Nyokong, Tebello , Li, Minzhi , Zhu, Weihua
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/240732 , vital:50866 , xlink:href="https://doi.org/10.1142/S1088424616500231"
- Description: An in-depth study of the electronic structure of a 1,4-diazabicyclo[2.2.2]octane (DABCO) induced molecular self-assembled xanthene-bridged and amide-bonded porphyrin dimer is reported. Density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations are used to identify trends in the optical spectroscopic properties. B3LYP geometry optimization predicts the formation of an almost perfectly eclipsed structure with respect to the two porphyrin rings with the analogous pyrrole nitrogens separated by 7.7–8.1 Å. The observed distinctive derivative-shaped band morphology of the pseudo-Faraday-A11 terms in the MCD spectra has been used to identify the main electronic Q and B-bands and to validate the TD-DFT calculations. The absence of a discernible splitting of the redox steps or a quenching of the fluorescence demonstrates that there is no significant exciton coupling between the two porphyrin rings.
- Full Text:
- Date Issued: 2016
A psychosocial study of young adults’ experiences of their sibling’s mental illness
- Authors: Laurie, Gina
- Date: 2017
- Subjects: Brothers and sisters of people with disabilities -- South Africa -- Case studies , Brothers and sisters of people with disabilities -- Psychology , Mentally ill -- Family relationships , Mentally ill -- Care -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/6165 , vital:21053
- Description: There are a number of studies that investigate the experiences of mental illness in the context of sibling relationships. However, these studies have not focused on young adulthood and limited research has been conducted in South Africa. This research uses a psychosocial framework which combines psychoanalytic theory and social constructionism to account for individual subjectivity and social influences. This method sought to answer two main research questions: how do young adults construct their experiences of having a sibling with a mental illness and with what effects, and how might we understand the emotional investments in these constructions? Six participants were interviewed and the findings suggest that participants draw on four main discourses in constructing their siblings’ mental illness: a discourse of mental illness as a sickness, a discourse of mental illness as part of the person, a discourse of mental illness as bad behaviour, and a discourse of mental illness as a spiritual issue. These discourses and the function of these discourses are discussed. Furthermore, an extract from one participant is examined in a case study format so as to explore the emotional investments in the discourse of mental illness as bad behaviour, arguing that her investments in this discourse serves to protect her by enabling her to manage feelings of not being ‘good enough’.
- Full Text:
- Date Issued: 2017
- Authors: Laurie, Gina
- Date: 2017
- Subjects: Brothers and sisters of people with disabilities -- South Africa -- Case studies , Brothers and sisters of people with disabilities -- Psychology , Mentally ill -- Family relationships , Mentally ill -- Care -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/6165 , vital:21053
- Description: There are a number of studies that investigate the experiences of mental illness in the context of sibling relationships. However, these studies have not focused on young adulthood and limited research has been conducted in South Africa. This research uses a psychosocial framework which combines psychoanalytic theory and social constructionism to account for individual subjectivity and social influences. This method sought to answer two main research questions: how do young adults construct their experiences of having a sibling with a mental illness and with what effects, and how might we understand the emotional investments in these constructions? Six participants were interviewed and the findings suggest that participants draw on four main discourses in constructing their siblings’ mental illness: a discourse of mental illness as a sickness, a discourse of mental illness as part of the person, a discourse of mental illness as bad behaviour, and a discourse of mental illness as a spiritual issue. These discourses and the function of these discourses are discussed. Furthermore, an extract from one participant is examined in a case study format so as to explore the emotional investments in the discourse of mental illness as bad behaviour, arguing that her investments in this discourse serves to protect her by enabling her to manage feelings of not being ‘good enough’.
- Full Text:
- Date Issued: 2017
A chiral hemiporphyrazine derivative
- Wu, Yanping, Gai, Lizhi, Xiao, Xuqiong, Lu, Hua, Li, Zhifang, Mack, John, Harris, Jessica, Nyokong, Tebello, Shen, Zhen
- Authors: Wu, Yanping , Gai, Lizhi , Xiao, Xuqiong , Lu, Hua , Li, Zhifang , Mack, John , Harris, Jessica , Nyokong, Tebello , Shen, Zhen
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/240404 , vital:50831 , xlink:href="https://doi.org/10.1002/asia.201600754"
- Description: The synthesis of an optically active hemiporphyrazine with chiral binaphthyl substituents (1) is reported, providing the first example of the incorporation of an intrinsically chiral moiety into the macrocyclic core of a hemiporphyrazine analogue. A negative circular dichroism (CD) signal is observed in the 325–450 nm region of the CD spectrum of (S,S)-1, while mainly positive bands are observed in the 220–325 nm region. Mirror symmetry is observed across the entire wavelength range of the CD spectra of (R,R)-1 and (S,S)-1. An irreversible one-electron oxidation wave with an onset potential at 1.07 V is observed by cyclic voltammetry, along with a reversible one-electron reduction wave at −0.85 V. Density functional calculations reproduce the experimentally observed data and trends, and provide further insight into the nature of the electronic transitions.
- Full Text:
- Date Issued: 2016
- Authors: Wu, Yanping , Gai, Lizhi , Xiao, Xuqiong , Lu, Hua , Li, Zhifang , Mack, John , Harris, Jessica , Nyokong, Tebello , Shen, Zhen
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/240404 , vital:50831 , xlink:href="https://doi.org/10.1002/asia.201600754"
- Description: The synthesis of an optically active hemiporphyrazine with chiral binaphthyl substituents (1) is reported, providing the first example of the incorporation of an intrinsically chiral moiety into the macrocyclic core of a hemiporphyrazine analogue. A negative circular dichroism (CD) signal is observed in the 325–450 nm region of the CD spectrum of (S,S)-1, while mainly positive bands are observed in the 220–325 nm region. Mirror symmetry is observed across the entire wavelength range of the CD spectra of (R,R)-1 and (S,S)-1. An irreversible one-electron oxidation wave with an onset potential at 1.07 V is observed by cyclic voltammetry, along with a reversible one-electron reduction wave at −0.85 V. Density functional calculations reproduce the experimentally observed data and trends, and provide further insight into the nature of the electronic transitions.
- Full Text:
- Date Issued: 2016
Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors
- Bodill, Taryn, Conibear, Anne C, Mutorwa, Marius K, Goble, Jessica L, Blatch, Gregory L, Lobb, Kevin A, Klein, Rosalyn, Kaye, Perry T
- Authors: Bodill, Taryn , Conibear, Anne C , Mutorwa, Marius K , Goble, Jessica L , Blatch, Gregory L , Lobb, Kevin A , Klein, Rosalyn , Kaye, Perry T
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448912 , vital:74770 , xlink:href=""
- Description: DOXP-reductoisomerase (DXR) is a validated target for the development of antimalarial drugs to address the increase in resistant strains of Plasmodium falciparum. Series of aryl- and heteroarylcarbamoylphosphonic acids, their diethyl esters and disodium salts have been prepared as analogues of the potent DXR inhibitor fosmidomycin. The effects of the carboxamide N-substituents and the length of the methylene linker have been explored using in silico docking studies, saturation transfer difference NMR spectroscopy and enzyme inhibition assays using both EcDXR and PfDXR. These studies indicate an optimal linker length of two methylene units and have confirmed the importance of an additional binding pocket in the PfDXR active site. Insights into the constraints of the PfDXR binding site provide additional scope for the rational design of DXR inhibitors with increased ligand–receptor interactions.
- Full Text:
- Date Issued: 2013
- Authors: Bodill, Taryn , Conibear, Anne C , Mutorwa, Marius K , Goble, Jessica L , Blatch, Gregory L , Lobb, Kevin A , Klein, Rosalyn , Kaye, Perry T
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448912 , vital:74770 , xlink:href=""
- Description: DOXP-reductoisomerase (DXR) is a validated target for the development of antimalarial drugs to address the increase in resistant strains of Plasmodium falciparum. Series of aryl- and heteroarylcarbamoylphosphonic acids, their diethyl esters and disodium salts have been prepared as analogues of the potent DXR inhibitor fosmidomycin. The effects of the carboxamide N-substituents and the length of the methylene linker have been explored using in silico docking studies, saturation transfer difference NMR spectroscopy and enzyme inhibition assays using both EcDXR and PfDXR. These studies indicate an optimal linker length of two methylene units and have confirmed the importance of an additional binding pocket in the PfDXR active site. Insights into the constraints of the PfDXR binding site provide additional scope for the rational design of DXR inhibitors with increased ligand–receptor interactions.
- Full Text:
- Date Issued: 2013
Lumberjacks and hoodrats: negotiating subject positions of lesbian representation in two South African television programmes
- Authors: Donaldson, Natalie
- Date: 2011
- Subjects: Lesbianism on television -- Research -- South Africa , Lesbians -- Research -- South Africa , Gay rights -- Research -- South Africa , Television actors and actresses -- Research -- South Africa
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2964 , http://hdl.handle.net/10962/d1002473 , Lesbianism on television -- Research -- South Africa , Lesbians -- Research -- South Africa , Gay rights -- Research -- South Africa , Television actors and actresses -- Research -- South Africa
- Description: With the inclusion of sexual orientation in the Equality clause of the post-Apartheid constitution which demands equal rights and protection for all individuals regardless of sexual orientation, South Africa has been praised as one of the most liberal countries in the world. Because of this legal equality, gay and lesbian experiences have become a lot more visible in every day South African lives. This includes visibility in South African television programmes and film. Today, a number of South African produced television programmes have included at least one lesbian character in their storyline and many LGBTIQ activist organisations have deemed this increased visibility as a positive step for LGBTIQ rights. However, discriminatory discourses such as same-sex sexualities as 'un-African ' and unnatural, which often result in brutal hate crimes against LGBTIQ individuals (such as corrective rape), contribute to the social and cultural intolerance of same-sex sexualities. South African research into the lives of lesbian women has often related lesbian experience to that of gay men or has focused on lesbian women as victims of corrective rape and oppressive practices at the hands of the dominant heteronormative culture. This research was a discursive reception study, using three focus group discussions with self-identified lesbian audiences (black and white). The study explored how this audience received (interpreted/talked about) the available fictional representations of 'black' lesbian women and 'white' lesbian women in three clips from two South African television programmes, Society and The Mating Game. Using Wetherell's (1998) critical discursive psychology approach, this research focused on examining the 1) Subject positions made available in/by these representations; 2) Interpretive repertoires used by the audience in appropriating and/or negotiating and/or reSisting these subject positions; and 3) Ideological dilemmas experienced by participants in this negotiation process. The predominant subject positions made available in these representations were differentiated according to binary racial categories of white lesbian women and black lesbian women. For example, participants positioned white lesbian women as "lumberjacks" and "tomboys" while black lesbian women were positioned as "township lesbians" and "hood rats". In working with these subject positions, participants drew on interpretative repertoires of othering and otherness as well as interpretative repertoires of survival. In negotiating with these subject positions and others found in the discussions, ideological dilemmas often arose when participants found themselves having to draw on interpretative repertoires which extend from a heteronormative discourse. These kinds of interpretative repertoires included religion, nature, and compromise which contradicted and created a troubled position when used in relation to the participants' lesbian sexualities. Therefore, when the ideological dilemma and troubled position became apparent, participants had to work to repair the troubled position by justifying their use of these heteronormative interpretative repertoires.
- Full Text:
- Date Issued: 2011
- Authors: Donaldson, Natalie
- Date: 2011
- Subjects: Lesbianism on television -- Research -- South Africa , Lesbians -- Research -- South Africa , Gay rights -- Research -- South Africa , Television actors and actresses -- Research -- South Africa
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: vital:2964 , http://hdl.handle.net/10962/d1002473 , Lesbianism on television -- Research -- South Africa , Lesbians -- Research -- South Africa , Gay rights -- Research -- South Africa , Television actors and actresses -- Research -- South Africa
- Description: With the inclusion of sexual orientation in the Equality clause of the post-Apartheid constitution which demands equal rights and protection for all individuals regardless of sexual orientation, South Africa has been praised as one of the most liberal countries in the world. Because of this legal equality, gay and lesbian experiences have become a lot more visible in every day South African lives. This includes visibility in South African television programmes and film. Today, a number of South African produced television programmes have included at least one lesbian character in their storyline and many LGBTIQ activist organisations have deemed this increased visibility as a positive step for LGBTIQ rights. However, discriminatory discourses such as same-sex sexualities as 'un-African ' and unnatural, which often result in brutal hate crimes against LGBTIQ individuals (such as corrective rape), contribute to the social and cultural intolerance of same-sex sexualities. South African research into the lives of lesbian women has often related lesbian experience to that of gay men or has focused on lesbian women as victims of corrective rape and oppressive practices at the hands of the dominant heteronormative culture. This research was a discursive reception study, using three focus group discussions with self-identified lesbian audiences (black and white). The study explored how this audience received (interpreted/talked about) the available fictional representations of 'black' lesbian women and 'white' lesbian women in three clips from two South African television programmes, Society and The Mating Game. Using Wetherell's (1998) critical discursive psychology approach, this research focused on examining the 1) Subject positions made available in/by these representations; 2) Interpretive repertoires used by the audience in appropriating and/or negotiating and/or reSisting these subject positions; and 3) Ideological dilemmas experienced by participants in this negotiation process. The predominant subject positions made available in these representations were differentiated according to binary racial categories of white lesbian women and black lesbian women. For example, participants positioned white lesbian women as "lumberjacks" and "tomboys" while black lesbian women were positioned as "township lesbians" and "hood rats". In working with these subject positions, participants drew on interpretative repertoires of othering and otherness as well as interpretative repertoires of survival. In negotiating with these subject positions and others found in the discussions, ideological dilemmas often arose when participants found themselves having to draw on interpretative repertoires which extend from a heteronormative discourse. These kinds of interpretative repertoires included religion, nature, and compromise which contradicted and created a troubled position when used in relation to the participants' lesbian sexualities. Therefore, when the ideological dilemma and troubled position became apparent, participants had to work to repair the troubled position by justifying their use of these heteronormative interpretative repertoires.
- Full Text:
- Date Issued: 2011
Hugh Tracey memorial service
- Jessica Bailey, Tracey, Andrew T N
- Authors: Jessica Bailey , Tracey, Andrew T N
- Date: 1977
- Subjects: Tracey, Hugh , Memorial service , Cello , Sub-Saharan African music , Africa South Africa Saronde Farm f-sa
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/112670 , vital:33635 , International Library of African Music, Rhodes University, Grahamstown, South Africa , ATC129b-01
- Description: Cello performance in tribute of Hugh Tracey
- Full Text: false
- Date Issued: 1977
- Authors: Jessica Bailey , Tracey, Andrew T N
- Date: 1977
- Subjects: Tracey, Hugh , Memorial service , Cello , Sub-Saharan African music , Africa South Africa Saronde Farm f-sa
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/112670 , vital:33635 , International Library of African Music, Rhodes University, Grahamstown, South Africa , ATC129b-01
- Description: Cello performance in tribute of Hugh Tracey
- Full Text: false
- Date Issued: 1977
Rhodes University Graduation Ceremony 2016
- Authors: Rhodes University
- Date: 2016
- Language: English
- Type: text
- Identifier: vital:8150 , http://hdl.handle.net/10962/d1021288
- Description: Rhodes University Graduation Ceremonies 2016 [at] 1820 Settlers National Monument Thursday, 31 March at 10.00 & 17:00 [and] Friday, 1 April at 10:00; 14:30 & 18:30 [and] Saturday, 2 April at 10:00
- Full Text:
- Date Issued: 2016
- Authors: Rhodes University
- Date: 2016
- Language: English
- Type: text
- Identifier: vital:8150 , http://hdl.handle.net/10962/d1021288
- Description: Rhodes University Graduation Ceremonies 2016 [at] 1820 Settlers National Monument Thursday, 31 March at 10.00 & 17:00 [and] Friday, 1 April at 10:00; 14:30 & 18:30 [and] Saturday, 2 April at 10:00
- Full Text:
- Date Issued: 2016
Report containing learning, reflection and evaluation based on social learning:
- Burt, Jane C, Wilson, Jessica, Copteros, Athina, Lotz-Sisitka, Heila, Pereira, Taryn, Mokoena, Samson, Munnik, Victor, Ngcozela, Thabang, Lusithi, Thabo
- Authors: Burt, Jane C , Wilson, Jessica , Copteros, Athina , Lotz-Sisitka, Heila , Pereira, Taryn , Mokoena, Samson , Munnik, Victor , Ngcozela, Thabang , Lusithi, Thabo
- Date: 2016
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142005 , vital:38023 , ISBN WRC Report no K5/2313 Deliverable 7
- Description: This report forms the seventh deliverable in the NWRS2 citizen monitoring project and builds on the previous 6 deliverables, which include methodology for the project (Del 1), an assessment of civil society involvement in water policy (Del 2), an overview of the social learning approach and introduction to the case studies (Del 3), draft citizen monitoring guidelines (Del 4), an update on social learning to-date, including action plans (Del 5) and a report on a description and assessment of the case studies (Del 6). This report describes the last social learning module of the ‘Changing Practice’ course and highlights preliminary reflections on the learning that has taken place during this course. The report also describes the plans that were taken at the follow up research meeting. Finally we present the approach towards evaluating the role of social learning in the project as a whole.
- Full Text:
- Date Issued: 2016
- Authors: Burt, Jane C , Wilson, Jessica , Copteros, Athina , Lotz-Sisitka, Heila , Pereira, Taryn , Mokoena, Samson , Munnik, Victor , Ngcozela, Thabang , Lusithi, Thabo
- Date: 2016
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142005 , vital:38023 , ISBN WRC Report no K5/2313 Deliverable 7
- Description: This report forms the seventh deliverable in the NWRS2 citizen monitoring project and builds on the previous 6 deliverables, which include methodology for the project (Del 1), an assessment of civil society involvement in water policy (Del 2), an overview of the social learning approach and introduction to the case studies (Del 3), draft citizen monitoring guidelines (Del 4), an update on social learning to-date, including action plans (Del 5) and a report on a description and assessment of the case studies (Del 6). This report describes the last social learning module of the ‘Changing Practice’ course and highlights preliminary reflections on the learning that has taken place during this course. The report also describes the plans that were taken at the follow up research meeting. Finally we present the approach towards evaluating the role of social learning in the project as a whole.
- Full Text:
- Date Issued: 2016
La femme dans l'oeuvre litteraire de Jean-Paul Sartre
- Authors: Seiler, Miriam Zimet
- Date: 1977
- Subjects: Sartre, Jean-Paul, 1905-1980 -- Criticism and interpretation
- Language: French
- Type: Thesis , Masters , MA
- Identifier: vital:3641 , http://hdl.handle.net/10962/d1014302
- Description: [From introduction]. Pourquoi examiner Ie rôle de la femme dans l' oeuvre de Sartre? Jean-Paul Sartre est l'un des philosophes les plus importants de ce siècle, un philosophe qui s'est consacré ấ un examen de l'homme et de ses rapports avec l'existence par la liberté conscienter; un penseur qui a montré son individualisme dans le domaine de la politique, n'acceptant que ce qu'il trouve défendable; un romancier et un dramaturge dont l'oeuvre a connu un succès mondial.
- Full Text:
- Date Issued: 1977
- Authors: Seiler, Miriam Zimet
- Date: 1977
- Subjects: Sartre, Jean-Paul, 1905-1980 -- Criticism and interpretation
- Language: French
- Type: Thesis , Masters , MA
- Identifier: vital:3641 , http://hdl.handle.net/10962/d1014302
- Description: [From introduction]. Pourquoi examiner Ie rôle de la femme dans l' oeuvre de Sartre? Jean-Paul Sartre est l'un des philosophes les plus importants de ce siècle, un philosophe qui s'est consacré ấ un examen de l'homme et de ses rapports avec l'existence par la liberté conscienter; un penseur qui a montré son individualisme dans le domaine de la politique, n'acceptant que ce qu'il trouve défendable; un romancier et un dramaturge dont l'oeuvre a connu un succès mondial.
- Full Text:
- Date Issued: 1977
Rhodes University Graduation Ceremony 2017
- Authors: Rhodes University
- Date: 2017
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/58067 , vital:27061
- Description: 2017 Graduation Ceremony, Umsitho Wothweso-Zidanga, Gradeplegtigheid [at] 1820 Settlers National Monument, Thursday, 20 April until Saturday, 22 April 2017.
- Full Text:
- Date Issued: 2017
- Authors: Rhodes University
- Date: 2017
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/58067 , vital:27061
- Description: 2017 Graduation Ceremony, Umsitho Wothweso-Zidanga, Gradeplegtigheid [at] 1820 Settlers National Monument, Thursday, 20 April until Saturday, 22 April 2017.
- Full Text:
- Date Issued: 2017
Rhodes University Graduation Ceremony 2011
- Authors: Rhodes University
- Date: 2011
- Language: English
- Type: text
- Identifier: vital:8136 , http://hdl.handle.net/10962/d1007246
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 7 April at 18.00 [and] Friday, 8 April at 10:30; 14:30 & 18:00 [and] Saturday, 9 April at 10:30
- Full Text:
- Date Issued: 2011
- Authors: Rhodes University
- Date: 2011
- Language: English
- Type: text
- Identifier: vital:8136 , http://hdl.handle.net/10962/d1007246
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 7 April at 18.00 [and] Friday, 8 April at 10:30; 14:30 & 18:00 [and] Saturday, 9 April at 10:30
- Full Text:
- Date Issued: 2011
Rhodes University 2018 Graduation Ceremony: 1820 Settlers' National Monument, Saturday, 7 April at 09:30
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64624 , vital:28566 , https://www.youtube.com/watch?v=I1inTS4jwWE , https://www.youtube.com/watch?v=mPiJiLEQhsE , https://www.youtube.com/watch?v=6kiZBy3D9SM , https://www.youtube.com/watch?v=oVj1DRaA4uw , https://www.youtube.com/watch?v=uvvRxNwFo-o
- Description: Rhodes University 2018 Graduation Programme, 7 April at 09:30: Bachelor’s: Diploma in Fine Art, Bachelor of Arts, Bachelor of Fine Art. Honours: Bachelor of Social Science Honours. Master’s: Master of Fine Art, Master of Social Science. Doctorate: PhD in Humanities.
- Full Text:
- Date Issued: 2018
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64624 , vital:28566 , https://www.youtube.com/watch?v=I1inTS4jwWE , https://www.youtube.com/watch?v=mPiJiLEQhsE , https://www.youtube.com/watch?v=6kiZBy3D9SM , https://www.youtube.com/watch?v=oVj1DRaA4uw , https://www.youtube.com/watch?v=uvvRxNwFo-o
- Description: Rhodes University 2018 Graduation Programme, 7 April at 09:30: Bachelor’s: Diploma in Fine Art, Bachelor of Arts, Bachelor of Fine Art. Honours: Bachelor of Social Science Honours. Master’s: Master of Fine Art, Master of Social Science. Doctorate: PhD in Humanities.
- Full Text:
- Date Issued: 2018
Rhodes University 2018 Graduation Ceremony: 1820 Settlers' National Monument, Friday, 6 April at 09:30
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64590 , vital:28563 , https://www.youtube.com/watch?v=Ae_eNPkpqL8 , https://www.youtube.com/watch?v=HNB6ZTKWmGw , https://www.youtube.com/watch?v=vqz7OftlW7M , https://www.youtube.com/watch?v=ALxeywz_eYs
- Description: Rhodes University 2018 Graduation Programme, 6 April at 09:30: Bachelor’s: Bachelor of Science, Bachelor of Science (Information Systems),Bachelor of Science (Software Development) Honours: Bachelor of Science Honours. Doctorate: PhD in Science.
- Full Text:
- Date Issued: 2018
- Authors: Rhodes University
- Date: 2018
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/64590 , vital:28563 , https://www.youtube.com/watch?v=Ae_eNPkpqL8 , https://www.youtube.com/watch?v=HNB6ZTKWmGw , https://www.youtube.com/watch?v=vqz7OftlW7M , https://www.youtube.com/watch?v=ALxeywz_eYs
- Description: Rhodes University 2018 Graduation Programme, 6 April at 09:30: Bachelor’s: Bachelor of Science, Bachelor of Science (Information Systems),Bachelor of Science (Software Development) Honours: Bachelor of Science Honours. Doctorate: PhD in Science.
- Full Text:
- Date Issued: 2018
Rhodes University Graduation Ceremony 2012
- Authors: Rhodes University
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:8135 , http://hdl.handle.net/10962/d1007245
- Description: Rhodes University Graduation Ceremonies 2012 [at] 1820 Settlers National Monument Thursday, 12 April at 18.00 [and] Friday, 13 April at 10:30; 14:30 & 18:00 [and] Saturday, 14 April at 10:30 , Rhodes University Awards, Scholarships, Bursaries and Prizes 2012
- Full Text:
- Date Issued: 2012
- Authors: Rhodes University
- Date: 2012
- Language: English
- Type: text
- Identifier: vital:8135 , http://hdl.handle.net/10962/d1007245
- Description: Rhodes University Graduation Ceremonies 2012 [at] 1820 Settlers National Monument Thursday, 12 April at 18.00 [and] Friday, 13 April at 10:30; 14:30 & 18:00 [and] Saturday, 14 April at 10:30 , Rhodes University Awards, Scholarships, Bursaries and Prizes 2012
- Full Text:
- Date Issued: 2012
The Southern African Program on Ecosystem Change and Society: an emergent community of practice
- Biggs, Reinette, Reyers, Belinda, Blanchard, Ryan, Clements, Hayley S, Cockburn, Jessica J, Cumming, Graeme S, Cundill, Georgina, de Vos, Alta, Dziba, Luthando E, Esler, Karen J, Fabricius, Christo, Hamann, Maike, Henriksson, Rebecka, Kotschy, Karen, Lindborg, Regina, Luvuno, Linda, Masterson, Vanessa A, Nel, Jeanne L, O'Farrell, Patrick, Palmer, Carolyn G, Pereira, Laura, Pollard, Sharon, Preiser, Rika, Roux, Dirk J, Scholes, Robert J, Selomane, Odirlwe, Shackleton, Charlie M, Shackleton, Sheona E, Sitas, Nadia, Slingsby, Jasper A, Spierenburg, Marja, Tengö, Maria
- Authors: Biggs, Reinette , Reyers, Belinda , Blanchard, Ryan , Clements, Hayley S , Cockburn, Jessica J , Cumming, Graeme S , Cundill, Georgina , de Vos, Alta , Dziba, Luthando E , Esler, Karen J , Fabricius, Christo , Hamann, Maike , Henriksson, Rebecka , Kotschy, Karen , Lindborg, Regina , Luvuno, Linda , Masterson, Vanessa A , Nel, Jeanne L , O'Farrell, Patrick , Palmer, Carolyn G , Pereira, Laura , Pollard, Sharon , Preiser, Rika , Roux, Dirk J , Scholes, Robert J , Selomane, Odirlwe , Shackleton, Charlie M , Shackleton, Sheona E , Sitas, Nadia , Slingsby, Jasper A , Spierenburg, Marja , Tengö, Maria
- Date: 2023
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/401330 , vital:69726 , xlink:href="https://doi.org/10.1080/26395916.2022.2150317"
- Description: Sustainability-focused research networks and communities of practice have emerged as a key response and strategy to build capacity and knowledge to support transformation towards more sustainable, just and equitable futures. This paper synthesises insights from the development of a community of practice on social-ecological systems (SES) research in southern Africa over the past decade, linked to the international Programme on Ecosystem Change and Society (PECS). This community consists of a network of researchers who carry out place-based SES research in the southern African region. They interact through various cross-cutting working groups and also host a variety of public colloquia and student and practitioner training events. Known as the Southern African Program on Ecosystem Change and Society (SAPECS), its core objectives are to: (1) derive new approaches and empirical insights on SES dynamics in the southern African context; (2) have a tangible impact by mainstreaming knowledge into policy and practice; and (3) grow the community of practice engaged in SES research and governance, including researchers, students and practitioners. This paper reflects on experiences in building the SAPECS community, with the aim of supporting the development of similar networks elsewhere in the world, particularly in the Global South.
- Full Text:
- Date Issued: 2023
- Authors: Biggs, Reinette , Reyers, Belinda , Blanchard, Ryan , Clements, Hayley S , Cockburn, Jessica J , Cumming, Graeme S , Cundill, Georgina , de Vos, Alta , Dziba, Luthando E , Esler, Karen J , Fabricius, Christo , Hamann, Maike , Henriksson, Rebecka , Kotschy, Karen , Lindborg, Regina , Luvuno, Linda , Masterson, Vanessa A , Nel, Jeanne L , O'Farrell, Patrick , Palmer, Carolyn G , Pereira, Laura , Pollard, Sharon , Preiser, Rika , Roux, Dirk J , Scholes, Robert J , Selomane, Odirlwe , Shackleton, Charlie M , Shackleton, Sheona E , Sitas, Nadia , Slingsby, Jasper A , Spierenburg, Marja , Tengö, Maria
- Date: 2023
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/401330 , vital:69726 , xlink:href="https://doi.org/10.1080/26395916.2022.2150317"
- Description: Sustainability-focused research networks and communities of practice have emerged as a key response and strategy to build capacity and knowledge to support transformation towards more sustainable, just and equitable futures. This paper synthesises insights from the development of a community of practice on social-ecological systems (SES) research in southern Africa over the past decade, linked to the international Programme on Ecosystem Change and Society (PECS). This community consists of a network of researchers who carry out place-based SES research in the southern African region. They interact through various cross-cutting working groups and also host a variety of public colloquia and student and practitioner training events. Known as the Southern African Program on Ecosystem Change and Society (SAPECS), its core objectives are to: (1) derive new approaches and empirical insights on SES dynamics in the southern African context; (2) have a tangible impact by mainstreaming knowledge into policy and practice; and (3) grow the community of practice engaged in SES research and governance, including researchers, students and practitioners. This paper reflects on experiences in building the SAPECS community, with the aim of supporting the development of similar networks elsewhere in the world, particularly in the Global South.
- Full Text:
- Date Issued: 2023
Rhodes University Graduation Ceremony 2014
- Authors: Rhodes University
- Date: 2014
- Language: English
- Type: text
- Identifier: vital:8148 , http://hdl.handle.net/10962/d1009493
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 10 April at 10.00 & 17:00 [and] Friday, 11 April at 10:00; 14:30 & 18:00 [and] Saturday, 12 April at 10:00 , Rhodes University Awards, Scholarships,Bursaries and Prizes 2014
- Full Text:
- Date Issued: 2014
- Authors: Rhodes University
- Date: 2014
- Language: English
- Type: text
- Identifier: vital:8148 , http://hdl.handle.net/10962/d1009493
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 10 April at 10.00 & 17:00 [and] Friday, 11 April at 10:00; 14:30 & 18:00 [and] Saturday, 12 April at 10:00 , Rhodes University Awards, Scholarships,Bursaries and Prizes 2014
- Full Text:
- Date Issued: 2014
Aspekte van die erotiek in enkele romans van André P Brink
- Authors: Milton, Laura
- Date: 1987
- Subjects: Brink, André P (André Philippus), 1935-2015 -- Criticism and interpretation
- Language: Afrikaans
- Type: Thesis , Masters , MA
- Identifier: vital:3571 , http://hdl.handle.net/10962/d1002094 , Brink, André P (André Philippus), 1935-2015 -- Criticism and interpretation
- Description: Die doel van hierdie studie is om ondersoek in te stel na aspekte van die erotiek in enkele romans van André P. Brink. Die studie bestaan uit twee afsonderlike dele: genoem 'teorie' en 'praktyk'. In die teoretiese deel sal daar eerstens kortliks gekyk word na 'n definiering van enkele kernbegrippe - onder andere 'seksualiteit', 'erotiek' en 'pornografie'. Daar word nie gepoog om algemeen-geldende definisies te formuleer nie, maar eerder definisies wat nuttig is vir die doel van hierdie studie. Daarna sal ondersoek ingestel word na Brink self se teoretiese formulerings met betrekking tot die erotiek. In die tweede deel sal gekonsentreer word op die erotiek in die praktyk van Brink se romans. Eerstens sal die keuse van romans verduidelik word en dan sal daar oorgegaan word tot 'n bespreking van drie romans: Die ambassadeur (1963), Kennis van die Aand (1973) en 'n Oomblik in die wind (1975). Ten slotte sal die gevolgtrekkings van die studie kortliks saamgevat word (Introduction, p. 1)
- Full Text:
- Date Issued: 1987
- Authors: Milton, Laura
- Date: 1987
- Subjects: Brink, André P (André Philippus), 1935-2015 -- Criticism and interpretation
- Language: Afrikaans
- Type: Thesis , Masters , MA
- Identifier: vital:3571 , http://hdl.handle.net/10962/d1002094 , Brink, André P (André Philippus), 1935-2015 -- Criticism and interpretation
- Description: Die doel van hierdie studie is om ondersoek in te stel na aspekte van die erotiek in enkele romans van André P. Brink. Die studie bestaan uit twee afsonderlike dele: genoem 'teorie' en 'praktyk'. In die teoretiese deel sal daar eerstens kortliks gekyk word na 'n definiering van enkele kernbegrippe - onder andere 'seksualiteit', 'erotiek' en 'pornografie'. Daar word nie gepoog om algemeen-geldende definisies te formuleer nie, maar eerder definisies wat nuttig is vir die doel van hierdie studie. Daarna sal ondersoek ingestel word na Brink self se teoretiese formulerings met betrekking tot die erotiek. In die tweede deel sal gekonsentreer word op die erotiek in die praktyk van Brink se romans. Eerstens sal die keuse van romans verduidelik word en dan sal daar oorgegaan word tot 'n bespreking van drie romans: Die ambassadeur (1963), Kennis van die Aand (1973) en 'n Oomblik in die wind (1975). Ten slotte sal die gevolgtrekkings van die studie kortliks saamgevat word (Introduction, p. 1)
- Full Text:
- Date Issued: 1987