Iingoma zama Gqoboka
- Authors: Ngqoko Village locals , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko Village sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/319735 , vital:60215 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD150A-08
- Description: Traditional Xhosa song for special occasions with clapping accompaniment
- Full Text: false
- Date Issued: 1985
Ilizwi leNkosi yethu liyakuma ngonaphakade
- Authors: Zingisa Seminary Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Umtata sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415956 , vital:71303 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC146a-07
- Description: Catholic mass hymn, accompanied by the marimba.
- Full Text: false
- Date Issued: 1985
Influence of endogenous female sex-steroids on mutagen metabolism
- Authors: Goold, Richard David
- Date: 1985 , 2013-03-15
- Subjects: Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3819 , http://hdl.handle.net/10962/d1004919 , Mutagenesis , Drugs -- Metabolism , Steroid hormones -- Receptors , Cytochrome P-450
- Description: Cytochrome P-450, the terminal oxidase of the metabolic mono-oxygenase system, is thought to exist in multiple forms, which have differing substrate specificities, and are variably inducible by different enzyme inducers. Many mutagens, themselves unreactive, require metabolic activation by one or more of these cytochrome P-450-dependent microsomal enzymes for mutagenic activity. Such mutagens may be detected in the Salmonella mutagenicity test only by the incorporation of an hepatic microsomal (59) fraction into the assay (as a first approximation to in vivo metabolism). Induction of the microsomal enzymes by different agents enhances the metabolic activation of mutagens; in fact, many mutagens are only detected when the 59 fraction has been induced by appropriate agents. Inducers of the phenobarbital-type are known to enhance microsomal steroid hydroxylation when administered at supraphysiological levels, inducers of several mono-oxygenase activities. In turn, the steroids, have been reported to be The inductive effects of the female sex-steroids and the combined effects of steroid and phenobarbital (PB) pretreatment on the metabolic activation of four mutagens have been investigated using the Salmonella assay. Female Sprague-Dawley rats were pret reated with 17a-oestradiol (E2) or progesterone (PRG) , at a level of either 1 mg/kg or 20 mg / kg daily for 14 days. A duplicate set of similarly pretreated groups were also induced with PB. Hepatic microsomal fractions were prepared from each group and incubated with each of the te st mutagens in the presence of a tester strain known to detect each particular type of mutagen. Induction of the hepatic metabolizing system by PB increased the activation of the mutagens significantly (as reflected by an increased number of revertant prototrophic S .typhimurium colonies). The administration of PRG also caused significant, and dose-dependent, induction of the activation of af l atoxin B1, benzo(a)pyrene, and dimethylnitrosamine. In general, E2 exhibited no inductive effect, but it did produce an increase in the activation of aflatoxin B1 (a reaction which is known to be catalysed by a mono-oxygenase prefe rentially inducible by PB). When use was made of a microsomal fraction that was prepared from animals which were both steroidpretreated and induced by PB, mutagenic activation was of the same order of magnitude as that observed when induction was brought about by PB alone. The absence of additive effect, taken together with the observations already mentioned, indicate that steroids induce the same cytochrome isozymes that are induced by PB. The implications of sex-hormonal regulation of the metabolic activation of mutagens are briefly discussed. , KMBT_363 , Adobe Acrobat 9.53 Paper Capture Plug-in
- Full Text:
- Date Issued: 1985
Inganzi Lemvana
- Authors: Christ the New Man Centre Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Garankuwa f-sa
- Language: Setswana
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295729 , vital:57373 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD092-25
- Description: Sung mass at Christ the New Man Centre, GaRankuwa with drum accompaniment.
- Full Text: false
- Date Issued: 1985
Ingoma yentombe yabafana
- Authors: Mhlola, P , Composer Not Specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320707 , vital:60367 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-04
- Description: Traditional Xhosa song with clapping accompaniment
- Full Text: false
- Date Issued: 1985
INkosi mayibe nani
- Authors: Guguletu St Gabriel's Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Cape Town sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416910 , vital:71395 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC148b-15
- Description: Unaccompanied Catholic mass hymn.
- Full Text: false
- Date Issued: 1985
INkosi mayibe nani
- Authors: Guguletu St Gabriel's Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Cape Town sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/417557 , vital:71463 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC151b-01
- Description: Catholic mass hymn, accompanied by the drum and clapping.
- Full Text: false
- Date Issued: 1985
Intervarsity message 1985
- Authors: Henderson, Derek Scott
- Date: 1985
- Language: English
- Type: Text
- Identifier: vital:7481 , http://hdl.handle.net/10962/d1018358
- Full Text:
- Date Issued: 1985
Interview at Ngqoko
- Authors: Dargie, Dave , Ntyefe, James , Nofinishi, Dywili , Composer Not Specified
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko sa
- Language: English , isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320688 , vital:60365 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-02
- Description: Dave Dargie interview with James Ntyefe at his home
- Full Text: false
- Date Issued: 1985
Interview at Ngqoko
- Authors: Dargie, Dave , Mhlola, Panda , Nofinishi, Dywili , Composer Not Specified
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Ngqoko sa
- Language: English , isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320702 , vital:60366 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-03
- Description: Dave Dargie interview with Panda Mhlola at Nofinishi's home
- Full Text: false
- Date Issued: 1985
Interview at Xonxa
- Authors: Dargie, Dave , Mlanjeni , Mujekwani , Composer Not Specified
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Xonxa sa
- Language: English , isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/320683 , vital:60364 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD151-01
- Description: Dave Dargie interview with Mr Mlanjeni and Mr Mujekwani the Catechist on Dave's interest of history of Xonxa people and their knowledge of Ntsikana's Great hymn
- Full Text: false
- Date Issued: 1985
Intsimbi kaNtsikana = Ntsikana's Bell
- Authors: Lumko Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/415638 , vital:71272 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC143b-02
- Description: Catholic hymn in celebration of Dick's Silver Jubilee of priesthood with Marimba accompaniment.
- Full Text: false
- Date Issued: 1985
IRobane
- Authors: Dywili, Nongangakho , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko District f-sa
- Language: Xhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/293529 , vital:57096 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD089-05
- Description: Performer uses Umrhubhe bow to perform a traditional Xhosa song.
- Full Text: false
- Date Issued: 1985
ISitolotolo
- Authors: Dywili, Nongangakho , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko District f-sa
- Language: Xhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/293550 , vital:57097 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD089-06
- Description: Performer sings traditional Xhosa song with clapping accompaniment.
- Full Text: false
- Date Issued: 1985
ISitolotolo
- Authors: Dywili, Nongangakho , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Lumko District f-sa
- Language: Xhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/293560 , vital:57098 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD089-07
- Description: Performer uses Umrhubhe bow to perform a traditional Xhosa song.
- Full Text: false
- Date Issued: 1985
It is not an easy road
- Authors: Participants of Jouberton Workshop , Molutsi, Agnus , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa Jouberton f-sa
- Language: English
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/295261 , vital:57315 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD091-22
- Description: Unaccompanied participants at Jouberton workshop perform own composition.
- Full Text: false
- Date Issued: 1985
Jabulani
- Authors: Guguletu St Gabriel's Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Cape Town sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/417421 , vital:71452 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC151a-14
- Description: Catholic mass hymn, accompanied by the drum, Marimba and clapping.
- Full Text: false
- Date Issued: 1985
Jabulani
- Authors: Guguletu St Gabriel's Church Congregation , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Cape Town sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/416765 , vital:71383 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC148b-12
- Description: Catholic mass hymn, accompanied by the marimba xylophone.
- Full Text: false
- Date Issued: 1985
Jehova wamadinga
- Authors: Parish Church of Bernard Mizeki , Composer not specified , Dargie, Dave , Hodgson, Janet
- Date: 1985
- Subjects: Folk music , Sacred music , Field recordings , Africa, Sub-Saharan , Africa South Africa Mbekweni, Western Cape sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/446418 , vital:74506 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DDC193b-02
- Description: Religious song with drum accompaniment
- Full Text: false
- Date Issued: 1985
Jerusalem ikhaya lam
- Authors: Zionists , Composer not specified , Dargie, Dave
- Date: 1985
- Subjects: Folk music , Field recordings , Africa, Sub-Saharan , Africa South Africa City not specified f-sa
- Language: isiXhosa
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/296854 , vital:57513 , International Library of African Music, Rhodes University, Makhanda, South Africa , Dave Dargie Field Tapes, Rhodes University, Makhanda, South Africa , DD095-15
- Description: Zionist Church music.
- Full Text: false
- Date Issued: 1985