The endocannabinoid system in inflammatory bowel system
- Authors: Ababio, Frank James Kweku
- Date: 2014
- Subjects: Inflammatory bowel diseases , Gastrointestinal system , Gastrointestinal system -- Diseases
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10346 , http://hdl.handle.net/10948/d1020338
- Description: Crohn’s disease (CD) and ulcerative colitis (UC) constitute the two major forms of inflammatory bowel disease (IBD), which are disorders of chronic inflammation in the gastrointestinal tract that are associated with significant morbidity and socioeconomic burden. IBD patients with long-standing intestinal inflammation are more prone to developing colorectal cancer (CRC). Until now, none of the existing IBD treatments is able to heal the mucosal ulcerations satisfactorily. The endocannabinoid system (ECS), which comprises of endogenous cannabinoid ligands, their receptors, and metabolic enzymes, has been implicated in gut homeostasis, visceral sensation, inflammation and gastrointestinal motility. Available studies in rodent models of IBD suggest that enhancing the ECS tone may reduce inflammation and improve mucosal integrity. This evidence indicates that the components of the ECS seem well positioned to exert a protective role in IBD and also to offer a great opportunity for therapeutic exploitation. Despite the role of the ECS in the gut, the presence and function of the components of the ECS is not well characterised in human IBD. The primary aim of the study was to investigate the state of the major components of the ECS in human IBD and to establish whether IBD is associated with any changes of the components of the ECS. Cannabinoid CB1 and CB2 receptors, enzymes for endocannabinoid biosynthesis PLC, “LRAT”, NAPE-PLD and DAGL, and endocannabinoid metabolic enzymes FAAH and MAGL were analysed from colonic tissue samples of CD, UC and control patients by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) to determine the relative mRNA expression of the above genes. The RT-qPCR analysis showed that the mRNA expression of PLC, LRAT, and NAPE-PLD were unchanged in both CD and UC, whiles DAGL mRNA was decreased in UC but was unchanged in CD. The endocannabinoid degradation enzymes, FAAH mRNA expression was also unchanged in CD but decreased in UC, whereas the mRNA expression of MAGL was significantly decreased in both CD and UC. NAPE-PLD/FAAH and DAGL/MAGL ratios, an estimation of the balance of AEA and 2-AG levels, showed that AEA and 2-AG levels could be increased and unchanged, respectively, in IBD. The mRNA expression of CB1 was significantly decreased in CD and UC whilst CB2 mRNA expression was unchanged in both forms of IBD. The study demonstrated that the components of the ECS which were investigated were present in colonic tissues of both IBD patients and healthy individuals, but they appear to be off balance in CD and UC patients. The decreased CB1 receptors in IBD patients could be an important modifier in the disease and could also provide a possible pathoaetiological mechanism linking IBD and CRC. Although these findings look promising, more studies with larger sample size are required to characterise the components of the ECS in human IBD.
- Full Text:
- Date Issued: 2014
- Authors: Ababio, Frank James Kweku
- Date: 2014
- Subjects: Inflammatory bowel diseases , Gastrointestinal system , Gastrointestinal system -- Diseases
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10346 , http://hdl.handle.net/10948/d1020338
- Description: Crohn’s disease (CD) and ulcerative colitis (UC) constitute the two major forms of inflammatory bowel disease (IBD), which are disorders of chronic inflammation in the gastrointestinal tract that are associated with significant morbidity and socioeconomic burden. IBD patients with long-standing intestinal inflammation are more prone to developing colorectal cancer (CRC). Until now, none of the existing IBD treatments is able to heal the mucosal ulcerations satisfactorily. The endocannabinoid system (ECS), which comprises of endogenous cannabinoid ligands, their receptors, and metabolic enzymes, has been implicated in gut homeostasis, visceral sensation, inflammation and gastrointestinal motility. Available studies in rodent models of IBD suggest that enhancing the ECS tone may reduce inflammation and improve mucosal integrity. This evidence indicates that the components of the ECS seem well positioned to exert a protective role in IBD and also to offer a great opportunity for therapeutic exploitation. Despite the role of the ECS in the gut, the presence and function of the components of the ECS is not well characterised in human IBD. The primary aim of the study was to investigate the state of the major components of the ECS in human IBD and to establish whether IBD is associated with any changes of the components of the ECS. Cannabinoid CB1 and CB2 receptors, enzymes for endocannabinoid biosynthesis PLC, “LRAT”, NAPE-PLD and DAGL, and endocannabinoid metabolic enzymes FAAH and MAGL were analysed from colonic tissue samples of CD, UC and control patients by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) to determine the relative mRNA expression of the above genes. The RT-qPCR analysis showed that the mRNA expression of PLC, LRAT, and NAPE-PLD were unchanged in both CD and UC, whiles DAGL mRNA was decreased in UC but was unchanged in CD. The endocannabinoid degradation enzymes, FAAH mRNA expression was also unchanged in CD but decreased in UC, whereas the mRNA expression of MAGL was significantly decreased in both CD and UC. NAPE-PLD/FAAH and DAGL/MAGL ratios, an estimation of the balance of AEA and 2-AG levels, showed that AEA and 2-AG levels could be increased and unchanged, respectively, in IBD. The mRNA expression of CB1 was significantly decreased in CD and UC whilst CB2 mRNA expression was unchanged in both forms of IBD. The study demonstrated that the components of the ECS which were investigated were present in colonic tissues of both IBD patients and healthy individuals, but they appear to be off balance in CD and UC patients. The decreased CB1 receptors in IBD patients could be an important modifier in the disease and could also provide a possible pathoaetiological mechanism linking IBD and CRC. Although these findings look promising, more studies with larger sample size are required to characterise the components of the ECS in human IBD.
- Full Text:
- Date Issued: 2014
Cost comparison between repackaging bulk oral solid medicines and purchasing manufacturer-prepared patient-ready packs in the public sector in South Africa
- Authors: Abahamye, Aloysius
- Date: 2014
- Subjects: Packaging -- Cost control , Business logistics -- Costs , Drugs -- Packaging , Manufacturing processes
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10163 , http://hdl.handle.net/10948/d1020596 , Drugs -- Packaging
- Description: In an attempt to have medicines available in patient-ready packs (PRPs) prior to the dispensing process, the provincial medicine depots in South Africa have, for many years, been repackaging bulk medicines into PRPs. Notwithstanding the fact that bulk medicine packages may have been the only packages available from the manufacturers to service the Primary Health Care (PHC) sector, the main aim of this process was to ensure that medicines were available in PRPs for dispensing to patients, thus, minimising the time spent on each prescription by the pharmacist, pharmacist’s assistant or Nurse. Currently, some medicines are being procured in PRPs from the manufacturers, whereas others are still procured in bulk packs which must be repackaged into PRPs. After a thorough literature search, it was established that, up until this point in time, no studies have been performed to compare costs of repackaged medicines from bulk packs with costs of medicines procured from manufacturers in PRPs. There was very scanty literature comparing the use of medicines procured either in PRPs or bulk packs. However, literature on cost comparison between repackaging and purchasing of commercially available manufacturer-prepared PRPs was not identified.
- Full Text:
- Date Issued: 2014
- Authors: Abahamye, Aloysius
- Date: 2014
- Subjects: Packaging -- Cost control , Business logistics -- Costs , Drugs -- Packaging , Manufacturing processes
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: vital:10163 , http://hdl.handle.net/10948/d1020596 , Drugs -- Packaging
- Description: In an attempt to have medicines available in patient-ready packs (PRPs) prior to the dispensing process, the provincial medicine depots in South Africa have, for many years, been repackaging bulk medicines into PRPs. Notwithstanding the fact that bulk medicine packages may have been the only packages available from the manufacturers to service the Primary Health Care (PHC) sector, the main aim of this process was to ensure that medicines were available in PRPs for dispensing to patients, thus, minimising the time spent on each prescription by the pharmacist, pharmacist’s assistant or Nurse. Currently, some medicines are being procured in PRPs from the manufacturers, whereas others are still procured in bulk packs which must be repackaged into PRPs. After a thorough literature search, it was established that, up until this point in time, no studies have been performed to compare costs of repackaged medicines from bulk packs with costs of medicines procured from manufacturers in PRPs. There was very scanty literature comparing the use of medicines procured either in PRPs or bulk packs. However, literature on cost comparison between repackaging and purchasing of commercially available manufacturer-prepared PRPs was not identified.
- Full Text:
- Date Issued: 2014
Genetic and biological characterisation of a novel South African Plutella xylostella granulovirus (PlxyGV) isolate
- Authors: Abdulkadir, Fatima
- Date: 2014
- Subjects: Diamondback moth , Diamondback moth -- Control -- South Africa , Plutellidae -- Control -- South Africa , Baculoviruses , Cruciferae -- Diseases and pests -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4113 , http://hdl.handle.net/10962/d1013059
- Description: The diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae), is an important pest of cruciferous crops worldwide. The prolonged use of synthetic chemical insecticides as a primary means of control has resulted in the development of resistance in pest populations. In addition, the pest has also evolved resistance to the bacterial insecticidal protein of Bacillus thuringiensis which is also widely used as a method of control. Baculoviruses are considered as effective alternatives to conventional methods of control when incorporated into integrated pest management (IPM) programmes. These viruses target the larval stages of insects, are generally host-specific and are safe for use in the environment. This study aimed to isolate a baculovirus from a laboratory-reared P. xylostella colony, characterise it genetically and then evaluate its virulence against neonate and fourth instar larvae. A laboratory colony of P. xylostella was established using pupae and asymptomatic larvae collected from a cabbage plantation outside Grahamstown in the Eastern Cape province of South Africa. The colony flourished in the laboratory due to prime conditions and availability of food. The duration of development from egg to adult was determined by observation and imaging of the various life stages. The mean developmental time from egg to adult was observed to be 14.59 ± 0.21 days. The population of the insects increased rapidly in number leading to overcrowding of the insect colony, and hence appearance of larvae with viral symptoms. Occlusion bodies (OBs) were extracted from symptomatic larval cadavers and purified by glycerol gradient centrifugation. Analysis of the purified OBs by transmission electron microscopy revealed the presence of a granulovirus which was named PlxyGV-SA. The virus isolate was genetically characterised by restriction endonuclease analysis of the genomic DNA, and PCR amplification and sequencing of selected viral genes. The complete genome sequence of a Japanese P. xylostella granulovirus isolate, PlxyGV-Japan, has been deposited on the GenBank database providing a reference strain for comparison with DNA profiles and selected gene sequences of PlxyGV-SA. BLAST analysis of the granulin gene confirmed the isolation of a novel South African PlxyGV isolate. Comparison of the restriction profiles of PlxyGV-SA with profiles of PlxyGV-Japan and other documented PlxyGV profiles obtained by agarose gel electrophoresis revealed that PlxyGV-SA is a genetically distinct isolate. The data obtained from the sequencing and alignment of ecdysteroid UDP-glucosyltransferase (egt), late expression factor 8 (lef-8) and late expression factor 9 (lef-9) genes with those of PlxyGV-Japan also showed that PlxyGV-SA is a genetically different isolate. In order to determine the biological activity of PlxyGV-SA against neonate and fourth instar P. xylostella larvae, surface dose bioassays were conducted. The median lethal concentration of the virus required to kill 50% (LC₅₀) and 90% (LC₉₀) of the larvae was estimated by feeding insects with a range of doses. In addition, the time to kill 50% of the larvae (LT₅₀) was determined by feeding insects with the LC₉₀ concentration. Larval mortality was monitored daily until pupation. The data obtained from the dose response assays were subjected to probit analysis using Proban statistical software. The time response was determined using GraphPad Prism software (version 6.0). The LC₅₀ and LC₉₀ values for the neonate larvae were 3.56 × 10⁵ and 1.14 × 10⁷ OBs/ml respectively. The LT₅₀ was determined to be 104 hours. The neonate larvae were found to be more susceptible to infection than the fourth instar larvae with the same virus concentration. The concentrations used for the neonate larvae assay did not have a significant effect on the fourth instar as no mortality was recorded. This is the first study to describe a novel South African PlxyGV isolate and the results suggest that PlxyGV-SA has significant potential for development as an effective biopesticide for the control of P. xylostella in the field.
- Full Text:
- Date Issued: 2014
- Authors: Abdulkadir, Fatima
- Date: 2014
- Subjects: Diamondback moth , Diamondback moth -- Control -- South Africa , Plutellidae -- Control -- South Africa , Baculoviruses , Cruciferae -- Diseases and pests -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4113 , http://hdl.handle.net/10962/d1013059
- Description: The diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae), is an important pest of cruciferous crops worldwide. The prolonged use of synthetic chemical insecticides as a primary means of control has resulted in the development of resistance in pest populations. In addition, the pest has also evolved resistance to the bacterial insecticidal protein of Bacillus thuringiensis which is also widely used as a method of control. Baculoviruses are considered as effective alternatives to conventional methods of control when incorporated into integrated pest management (IPM) programmes. These viruses target the larval stages of insects, are generally host-specific and are safe for use in the environment. This study aimed to isolate a baculovirus from a laboratory-reared P. xylostella colony, characterise it genetically and then evaluate its virulence against neonate and fourth instar larvae. A laboratory colony of P. xylostella was established using pupae and asymptomatic larvae collected from a cabbage plantation outside Grahamstown in the Eastern Cape province of South Africa. The colony flourished in the laboratory due to prime conditions and availability of food. The duration of development from egg to adult was determined by observation and imaging of the various life stages. The mean developmental time from egg to adult was observed to be 14.59 ± 0.21 days. The population of the insects increased rapidly in number leading to overcrowding of the insect colony, and hence appearance of larvae with viral symptoms. Occlusion bodies (OBs) were extracted from symptomatic larval cadavers and purified by glycerol gradient centrifugation. Analysis of the purified OBs by transmission electron microscopy revealed the presence of a granulovirus which was named PlxyGV-SA. The virus isolate was genetically characterised by restriction endonuclease analysis of the genomic DNA, and PCR amplification and sequencing of selected viral genes. The complete genome sequence of a Japanese P. xylostella granulovirus isolate, PlxyGV-Japan, has been deposited on the GenBank database providing a reference strain for comparison with DNA profiles and selected gene sequences of PlxyGV-SA. BLAST analysis of the granulin gene confirmed the isolation of a novel South African PlxyGV isolate. Comparison of the restriction profiles of PlxyGV-SA with profiles of PlxyGV-Japan and other documented PlxyGV profiles obtained by agarose gel electrophoresis revealed that PlxyGV-SA is a genetically distinct isolate. The data obtained from the sequencing and alignment of ecdysteroid UDP-glucosyltransferase (egt), late expression factor 8 (lef-8) and late expression factor 9 (lef-9) genes with those of PlxyGV-Japan also showed that PlxyGV-SA is a genetically different isolate. In order to determine the biological activity of PlxyGV-SA against neonate and fourth instar P. xylostella larvae, surface dose bioassays were conducted. The median lethal concentration of the virus required to kill 50% (LC₅₀) and 90% (LC₉₀) of the larvae was estimated by feeding insects with a range of doses. In addition, the time to kill 50% of the larvae (LT₅₀) was determined by feeding insects with the LC₉₀ concentration. Larval mortality was monitored daily until pupation. The data obtained from the dose response assays were subjected to probit analysis using Proban statistical software. The time response was determined using GraphPad Prism software (version 6.0). The LC₅₀ and LC₉₀ values for the neonate larvae were 3.56 × 10⁵ and 1.14 × 10⁷ OBs/ml respectively. The LT₅₀ was determined to be 104 hours. The neonate larvae were found to be more susceptible to infection than the fourth instar larvae with the same virus concentration. The concentrations used for the neonate larvae assay did not have a significant effect on the fourth instar as no mortality was recorded. This is the first study to describe a novel South African PlxyGV isolate and the results suggest that PlxyGV-SA has significant potential for development as an effective biopesticide for the control of P. xylostella in the field.
- Full Text:
- Date Issued: 2014
Parents' experiences of monitoring their adolescents' compliance with diversion orders
- Authors: Abdulla, Zurina
- Date: 2014
- Subjects: Juvenile delinquents , Juvenile delinquents -- Family relationships -- South Africa , Juvenile justice, Administration of -- South Africa , Parent and child
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10006 , http://hdl.handle.net/10948/d1020090
- Description: The increased incidence of children committing crime and the realisation that the existing legislature dealing with offenders failed to cater for the rights and needs of child offenders gave rise to the introduction of the Child Justice Act 75 of 2008. This Act enables the South African criminal justice system to deal with children in a manner appropriate to their developmental stage. One of the initiatives introduced by the Act is termed ‘diversion’, where children are diverted from the criminal justice system into restorative developmental programmes, offered by organisations such as NICRO (National Institute for Crime Prevention and the Reintegration of Offenders). Their parents or guardians are tasked with the responsibility of monitoring their compliance with the diversion order in terms of Section 24(5) of the aforementioned Act. The monitoring responsibility assigned to the parents of diverted adolescents prompted the research question and aim of this study, namely to explore parents’ experiences in monitoring their adolescents’ compliance with diversion orders and to identify service needs in supporting parents in fulfilling their role as stipulated in the Act. This was a qualitative study that was exploratory-descriptive and contextual in nature. A non-probability purposive sampling technique was employed to identify the parents or guardians of adolescents aged 14 to 17 years that had been diverted to NICRO between June 2011 and June 2012. Individual semi-structured interviews were conducted with the selected parents, and the data collected was analysed using thematic data analysis. The trustworthiness of the research process and the findings was enhanced by employing a variety of data verification strategies. This research contributes to a greater understanding of parents’ monitoring experiences of their adolescents’ compliance with diversion orders. The study revealed that most parents experienced their role as an additional responsibility; they needed access to counseling and information on the child justice process.
- Full Text:
- Date Issued: 2014
- Authors: Abdulla, Zurina
- Date: 2014
- Subjects: Juvenile delinquents , Juvenile delinquents -- Family relationships -- South Africa , Juvenile justice, Administration of -- South Africa , Parent and child
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10006 , http://hdl.handle.net/10948/d1020090
- Description: The increased incidence of children committing crime and the realisation that the existing legislature dealing with offenders failed to cater for the rights and needs of child offenders gave rise to the introduction of the Child Justice Act 75 of 2008. This Act enables the South African criminal justice system to deal with children in a manner appropriate to their developmental stage. One of the initiatives introduced by the Act is termed ‘diversion’, where children are diverted from the criminal justice system into restorative developmental programmes, offered by organisations such as NICRO (National Institute for Crime Prevention and the Reintegration of Offenders). Their parents or guardians are tasked with the responsibility of monitoring their compliance with the diversion order in terms of Section 24(5) of the aforementioned Act. The monitoring responsibility assigned to the parents of diverted adolescents prompted the research question and aim of this study, namely to explore parents’ experiences in monitoring their adolescents’ compliance with diversion orders and to identify service needs in supporting parents in fulfilling their role as stipulated in the Act. This was a qualitative study that was exploratory-descriptive and contextual in nature. A non-probability purposive sampling technique was employed to identify the parents or guardians of adolescents aged 14 to 17 years that had been diverted to NICRO between June 2011 and June 2012. Individual semi-structured interviews were conducted with the selected parents, and the data collected was analysed using thematic data analysis. The trustworthiness of the research process and the findings was enhanced by employing a variety of data verification strategies. This research contributes to a greater understanding of parents’ monitoring experiences of their adolescents’ compliance with diversion orders. The study revealed that most parents experienced their role as an additional responsibility; they needed access to counseling and information on the child justice process.
- Full Text:
- Date Issued: 2014
Impacts of climate change on food security in southern Ghana : a community perspective
- Authors: Aboagye, Dickson Danso
- Date: 2014
- Subjects: Sustainable agriculture -- Ghana , Climatic changes -- Ghana , Food security -- Ghana
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9182 , http://hdl.handle.net/10948/d1020166
- Description: This study will examine the impacts of climate change on food security in Southern Ghana. Southern Ghana reveals that the district suffers post- harvest losses of about 8 percent of all cereals which hinders Ghana’s food security. Ghana still faces food insecurity due to high temperatures and low rainfall. This research therefore seeks to investigate what local communities of Southern Ghana are doing to address food insecurity problems with the advent of climate change. Several objectives to achieve this goal involves to identify factors hindering food security in Southern Ghana and to evaluate the extent that climate change has affected food security. A qualitative research approach was used by the researcher to come up with community strategies which this research seeks to address. Various conclusions such as community demand for support from the local government, sustainable irrigation programs, availability of pipe-borne water and environmental education were put in place, as possible solutions to the persisting food security problems in Southern Ghana.
- Full Text:
- Date Issued: 2014
- Authors: Aboagye, Dickson Danso
- Date: 2014
- Subjects: Sustainable agriculture -- Ghana , Climatic changes -- Ghana , Food security -- Ghana
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9182 , http://hdl.handle.net/10948/d1020166
- Description: This study will examine the impacts of climate change on food security in Southern Ghana. Southern Ghana reveals that the district suffers post- harvest losses of about 8 percent of all cereals which hinders Ghana’s food security. Ghana still faces food insecurity due to high temperatures and low rainfall. This research therefore seeks to investigate what local communities of Southern Ghana are doing to address food insecurity problems with the advent of climate change. Several objectives to achieve this goal involves to identify factors hindering food security in Southern Ghana and to evaluate the extent that climate change has affected food security. A qualitative research approach was used by the researcher to come up with community strategies which this research seeks to address. Various conclusions such as community demand for support from the local government, sustainable irrigation programs, availability of pipe-borne water and environmental education were put in place, as possible solutions to the persisting food security problems in Southern Ghana.
- Full Text:
- Date Issued: 2014
Political and religious identities : an exploration of changing identities amongst religious leaders in the Northern areas of Port Elizabeth
- Authors: Abrahams, Andre John
- Date: 2014
- Subjects: Religion and politics -- South Africa -- Port Elizabeth , Identification (Religion)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8314 , http://hdl.handle.net/10948/d1020087
- Description: The political transition from the oppressive apartheid system to post-apartheid South Africa has brought considerable change to the political climate. As a result of this transition, political and religious identities were also affected. This study explores the changing identities amongst religious leaders particularly in the Northern Areas of Port Elizabeth. The research has also explored how the advent of democracy has affected the political perspectives of these religious leaders who were ministering during apartheid. A qualitative research approach was used to frame the study, which employed an exploratory research design so as to understand the current political identities of these religious leaders. The sample of the study was purposively selected using the snowball sampling technique. As a means of collecting data in-depth interviews were conducted. The themes emanating from the study were recognised as being: - Church leaders reflecting on the political climate apparent in the Northern Areas of Port Elizabeth - Church leaders reflect reasons for limited political action from certain segments of the community sighting fear and poverty as central tenets. - Church leaders reveal close link between the church and politics during the apartheid period - The activities of the church in opposing the apartheid structure - Participants reflect on the role of Church leaders specifically during this period. - Church leaders articulate their disappointment in the political environment since 1994. - Church leaders reflect how race has affected the political climate since 1994 - The changing role of the church since 1994 - The growing silence on current political issues since 1994 Based on the identified themes conclusions could be drawn on the current political and religious identities of religious leaders compared to those adopted during the apartheid period. The outcome showed that religious leaders within the Northern Areas of Port Elizabeth are disappointed in the current political government but despite this have remained silent on political issues unlike the visible activism and vocal upheaval waged against the apartheid system.
- Full Text:
- Date Issued: 2014
- Authors: Abrahams, Andre John
- Date: 2014
- Subjects: Religion and politics -- South Africa -- Port Elizabeth , Identification (Religion)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8314 , http://hdl.handle.net/10948/d1020087
- Description: The political transition from the oppressive apartheid system to post-apartheid South Africa has brought considerable change to the political climate. As a result of this transition, political and religious identities were also affected. This study explores the changing identities amongst religious leaders particularly in the Northern Areas of Port Elizabeth. The research has also explored how the advent of democracy has affected the political perspectives of these religious leaders who were ministering during apartheid. A qualitative research approach was used to frame the study, which employed an exploratory research design so as to understand the current political identities of these religious leaders. The sample of the study was purposively selected using the snowball sampling technique. As a means of collecting data in-depth interviews were conducted. The themes emanating from the study were recognised as being: - Church leaders reflecting on the political climate apparent in the Northern Areas of Port Elizabeth - Church leaders reflect reasons for limited political action from certain segments of the community sighting fear and poverty as central tenets. - Church leaders reveal close link between the church and politics during the apartheid period - The activities of the church in opposing the apartheid structure - Participants reflect on the role of Church leaders specifically during this period. - Church leaders articulate their disappointment in the political environment since 1994. - Church leaders reflect how race has affected the political climate since 1994 - The changing role of the church since 1994 - The growing silence on current political issues since 1994 Based on the identified themes conclusions could be drawn on the current political and religious identities of religious leaders compared to those adopted during the apartheid period. The outcome showed that religious leaders within the Northern Areas of Port Elizabeth are disappointed in the current political government but despite this have remained silent on political issues unlike the visible activism and vocal upheaval waged against the apartheid system.
- Full Text:
- Date Issued: 2014
Relative contribution of wild foods to individual and household food security in the context of increasing vulnerability due to HIV/AIDS and climate variability
- Abu-Basutu, Keitometsi Ngulube
- Authors: Abu-Basutu, Keitometsi Ngulube
- Date: 2014
- Subjects: Wild foods -- South Africa -- Eastern Cape , Food security -- South Africa , Food supply -- South Africa , AIDS (Disease) -- Social aspects -- South Africa , HIV infections -- Social aspects -- South Africa , Chronically ill -- South Africa -- Economic conditions , Chronically ill -- South Africa -- Social conditions , Food -- Social aspects -- South Africa , Food -- Economic aspects -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4774 , http://hdl.handle.net/10962/d1010864 , Wild foods -- South Africa -- Eastern Cape , Food security -- South Africa , Food supply -- South Africa , AIDS (Disease) -- Social aspects -- South Africa , HIV infections -- Social aspects -- South Africa , Chronically ill -- South Africa -- Economic conditions , Chronically ill -- South Africa -- Social conditions , Food -- Social aspects -- South Africa , Food -- Economic aspects -- South Africa
- Description: Wild foods are an integral component of the household food basket, yet their quantified contribution to food security relative to other sources in the context of HIV/AIDS, climate change and variability remains underexplored. This study was carried out in Willowvale and Lesseyton which are rural communities in the Eastern Cape province of South Africa. Willowvale is a relatively remote, medium-rainfall coastal community, while Lesseyton is a peri-urban low rainfall inland community. Qualitative and quantitative methods were used to collect data from 78 HIV/AIDS afflicted households with 329 individuals and 87 non-afflicted households with 365 individuals in the two study sites. Households were visited quarterly over 12 months to assess food acquisition methods, dietary intake and quality, and levels of food security, and to determine strategies employed by households to cope with droughts. The wild foods investigated were wild meat, wild birds, wild fish, wild mushrooms, wild leafy vegetables and wild fruits. Diets were moderately well-balanced and limited in variety, with cereal items contributing 52 % to total calorie intake. Mid-upper arm circumference measurements showed that all respondents were adequately nourished. The bulk of the food consumed by households was purchased, with supplementation from own production, wild vegetables and wild fruits. In Willowvale, wild vegetables comprised 46 % of overall vegetable consumption for afflicted households and 32 % for non-afflicted households, while own fruit production comprised 100 % of fruit consumption. In Lesseyton, wild vegetables comprised only 6 % and 4 % of vegetable consumption for afflicted and non-afflicted households, while wild fruit comprised 63 % and 41 % for afflicted and non-afflicted households. More than 80 % of respondents from both afflicted and non-afflicted households had sufficient daily kilocalories, although the majority of afflicted households felt they were food insecure and sometimes collected wild foods as one of their multiple coping strategies. Hunting and gathering of wild foods was associated with site, household affliction status, gender, age and season. More than 80 % of respondents ate wild vegetables and said they were more drought tolerant than conventional vegetables, making them the most consumed wild food and approximately 16 % of respondents ate wild birds, making them the least consumed wild food. Approximately 14 % of respondents from afflicted households in Willowvale sold wild fish, whilst 34 % of respondents from afflicted households and 7 % from non-afflicted households sold wild fruits in Lesseyton. Strategies adopted by households to cope with droughts were different between the two study sites, and households in Willowvale used a wider range of strategies. Given the devastating effects of HIV/AIDS coupled with the drawbacks of climate change and variability on food security, wild foods represent a free and easy way for vulnerable households to obtain food.
- Full Text:
- Date Issued: 2014
- Authors: Abu-Basutu, Keitometsi Ngulube
- Date: 2014
- Subjects: Wild foods -- South Africa -- Eastern Cape , Food security -- South Africa , Food supply -- South Africa , AIDS (Disease) -- Social aspects -- South Africa , HIV infections -- Social aspects -- South Africa , Chronically ill -- South Africa -- Economic conditions , Chronically ill -- South Africa -- Social conditions , Food -- Social aspects -- South Africa , Food -- Economic aspects -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4774 , http://hdl.handle.net/10962/d1010864 , Wild foods -- South Africa -- Eastern Cape , Food security -- South Africa , Food supply -- South Africa , AIDS (Disease) -- Social aspects -- South Africa , HIV infections -- Social aspects -- South Africa , Chronically ill -- South Africa -- Economic conditions , Chronically ill -- South Africa -- Social conditions , Food -- Social aspects -- South Africa , Food -- Economic aspects -- South Africa
- Description: Wild foods are an integral component of the household food basket, yet their quantified contribution to food security relative to other sources in the context of HIV/AIDS, climate change and variability remains underexplored. This study was carried out in Willowvale and Lesseyton which are rural communities in the Eastern Cape province of South Africa. Willowvale is a relatively remote, medium-rainfall coastal community, while Lesseyton is a peri-urban low rainfall inland community. Qualitative and quantitative methods were used to collect data from 78 HIV/AIDS afflicted households with 329 individuals and 87 non-afflicted households with 365 individuals in the two study sites. Households were visited quarterly over 12 months to assess food acquisition methods, dietary intake and quality, and levels of food security, and to determine strategies employed by households to cope with droughts. The wild foods investigated were wild meat, wild birds, wild fish, wild mushrooms, wild leafy vegetables and wild fruits. Diets were moderately well-balanced and limited in variety, with cereal items contributing 52 % to total calorie intake. Mid-upper arm circumference measurements showed that all respondents were adequately nourished. The bulk of the food consumed by households was purchased, with supplementation from own production, wild vegetables and wild fruits. In Willowvale, wild vegetables comprised 46 % of overall vegetable consumption for afflicted households and 32 % for non-afflicted households, while own fruit production comprised 100 % of fruit consumption. In Lesseyton, wild vegetables comprised only 6 % and 4 % of vegetable consumption for afflicted and non-afflicted households, while wild fruit comprised 63 % and 41 % for afflicted and non-afflicted households. More than 80 % of respondents from both afflicted and non-afflicted households had sufficient daily kilocalories, although the majority of afflicted households felt they were food insecure and sometimes collected wild foods as one of their multiple coping strategies. Hunting and gathering of wild foods was associated with site, household affliction status, gender, age and season. More than 80 % of respondents ate wild vegetables and said they were more drought tolerant than conventional vegetables, making them the most consumed wild food and approximately 16 % of respondents ate wild birds, making them the least consumed wild food. Approximately 14 % of respondents from afflicted households in Willowvale sold wild fish, whilst 34 % of respondents from afflicted households and 7 % from non-afflicted households sold wild fruits in Lesseyton. Strategies adopted by households to cope with droughts were different between the two study sites, and households in Willowvale used a wider range of strategies. Given the devastating effects of HIV/AIDS coupled with the drawbacks of climate change and variability on food security, wild foods represent a free and easy way for vulnerable households to obtain food.
- Full Text:
- Date Issued: 2014
Structural bioinformatics analysis of the Hsp40 and Hsp70 molecular chaperones from humans
- Authors: Adeyemi, Samson Adebowale
- Date: 2014
- Subjects: Structural bioinformatics , Molecular chaperones , Heat shock proteins , Protein-protein interactions , Biomolecules
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4171 , http://hdl.handle.net/10962/d1020962
- Description: HSP70 is one of the most important families of molecular chaperone that regulate the folding and transport of client proteins in an ATP dependent manner. The ATPase activity of HSP70 is stimulated through an interaction with its family of HSP40 co-chaperones. There is evidence to suggest that specific partnerships occur between the different HSP40 and HSP70 isoforms. While some of the residues involved in the interaction are known, many of the residues governing the specificity of HSP40-HSP70 partnerships are not precisely defined. It is not currently possible to predict which HSP40 and HSP70 isoforms will interact. We attempted to use bioinformatics to identify residues involved in the specificity of the interaction between the J domain from HSP40 and the ATPase domain from the HSP70 isoforms from humans. A total of 49 HSP40 and 13 HSP70 sequences from humans were retrieved and used for subsequent analyses. The HSP40 J domains and HSP70 ATPase domains were extracted using python scripts and classified according to the subcellular localization of the proteins using localization prediction programs. Motif analysis was carried out using the full length HSP40 proteins and Multiple Sequence Alignment (MSA) was performed to identify conserved residues that may contribute to the J domain – ATPase domain interactions. Phylogenetic inference of the proteins was also performed in order to study their evolutionary relationship. Homology models of the J domains and ATPase domains were generated. The corresponding models were docked using HADDOCK server in order to analyze possible putative interactions between the partner proteins using the Protein Interactions Calculator (PIC). The level of residue conservation was found to be higher in Type I and II HSP40 than in Type III J proteins. While highly conserved residues on helixes II and III could play critical roles in J domain interactions with corresponding HSP70s, conserved residues on helixes I and IV seemed to be significant in keeping the J domain in its right orientation for functional interactions with HSP70s. Our results also showed that helixes II and III formed the interaction interface for binding to HSP70 ATPase domain as well as the linker residues. Finally, data based docking procedures, such as applied in this study, could be an effective method to investigate protein-protein interactions complex of biomolecules.
- Full Text:
- Date Issued: 2014
- Authors: Adeyemi, Samson Adebowale
- Date: 2014
- Subjects: Structural bioinformatics , Molecular chaperones , Heat shock proteins , Protein-protein interactions , Biomolecules
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4171 , http://hdl.handle.net/10962/d1020962
- Description: HSP70 is one of the most important families of molecular chaperone that regulate the folding and transport of client proteins in an ATP dependent manner. The ATPase activity of HSP70 is stimulated through an interaction with its family of HSP40 co-chaperones. There is evidence to suggest that specific partnerships occur between the different HSP40 and HSP70 isoforms. While some of the residues involved in the interaction are known, many of the residues governing the specificity of HSP40-HSP70 partnerships are not precisely defined. It is not currently possible to predict which HSP40 and HSP70 isoforms will interact. We attempted to use bioinformatics to identify residues involved in the specificity of the interaction between the J domain from HSP40 and the ATPase domain from the HSP70 isoforms from humans. A total of 49 HSP40 and 13 HSP70 sequences from humans were retrieved and used for subsequent analyses. The HSP40 J domains and HSP70 ATPase domains were extracted using python scripts and classified according to the subcellular localization of the proteins using localization prediction programs. Motif analysis was carried out using the full length HSP40 proteins and Multiple Sequence Alignment (MSA) was performed to identify conserved residues that may contribute to the J domain – ATPase domain interactions. Phylogenetic inference of the proteins was also performed in order to study their evolutionary relationship. Homology models of the J domains and ATPase domains were generated. The corresponding models were docked using HADDOCK server in order to analyze possible putative interactions between the partner proteins using the Protein Interactions Calculator (PIC). The level of residue conservation was found to be higher in Type I and II HSP40 than in Type III J proteins. While highly conserved residues on helixes II and III could play critical roles in J domain interactions with corresponding HSP70s, conserved residues on helixes I and IV seemed to be significant in keeping the J domain in its right orientation for functional interactions with HSP70s. Our results also showed that helixes II and III formed the interaction interface for binding to HSP70 ATPase domain as well as the linker residues. Finally, data based docking procedures, such as applied in this study, could be an effective method to investigate protein-protein interactions complex of biomolecules.
- Full Text:
- Date Issued: 2014
An evaluation of the role of child and youth care centres in the implementation of South Africa’s children’s act
- Authors: Agere, Leonard Munyaradzi
- Date: 2014
- Subjects: South Africa. Children's Act, 2005 , Children's rights -- South Africa , Child care services -- South Africa
- Language: English
- Type: Thesis , Masters , M SW
- Identifier: vital:11770 , http://hdl.handle.net/10353/d1015406 , South Africa. Children's Act, 2005 , Children's rights -- South Africa , Child care services -- South Africa
- Description: The aim of this study was to evaluate the role played by CYCCs to provide support and protection to children who have been found to be in need of care, according to the criteria given in the Children’s Act No. 38/2005 as amended. The study made use of a qualitative approach and the research design was provided by the case study. Data was gathered by means of semi-structured interviews and focus group discussions. The most important findings to emerge from the study were that the factors which affect the operation of CYCCs are either institutional, or else challenges arising from issues pertaining to infrastructure and human resources. However, it was also acknowledged that, despite the challenges which affect their ability to provide their services to young people, the CYCCs had also made progressive steps to halt the suppression of the fundamental rights of children. It has been recommended that the government should apply comprehensive funding to the objectives of the Children’s Act, which would entail increasing the subsidies to CYCCs. It has also been recommended that the Policy on Financial Rewards should call for the same benefits and salary scales to apply for professional staff working in the government and to those working in the CYCCs. The repercussions from failing to adjust to these recommendations will inevitably lead to the employment of a remedial model of care.
- Full Text:
- Date Issued: 2014
- Authors: Agere, Leonard Munyaradzi
- Date: 2014
- Subjects: South Africa. Children's Act, 2005 , Children's rights -- South Africa , Child care services -- South Africa
- Language: English
- Type: Thesis , Masters , M SW
- Identifier: vital:11770 , http://hdl.handle.net/10353/d1015406 , South Africa. Children's Act, 2005 , Children's rights -- South Africa , Child care services -- South Africa
- Description: The aim of this study was to evaluate the role played by CYCCs to provide support and protection to children who have been found to be in need of care, according to the criteria given in the Children’s Act No. 38/2005 as amended. The study made use of a qualitative approach and the research design was provided by the case study. Data was gathered by means of semi-structured interviews and focus group discussions. The most important findings to emerge from the study were that the factors which affect the operation of CYCCs are either institutional, or else challenges arising from issues pertaining to infrastructure and human resources. However, it was also acknowledged that, despite the challenges which affect their ability to provide their services to young people, the CYCCs had also made progressive steps to halt the suppression of the fundamental rights of children. It has been recommended that the government should apply comprehensive funding to the objectives of the Children’s Act, which would entail increasing the subsidies to CYCCs. It has also been recommended that the Policy on Financial Rewards should call for the same benefits and salary scales to apply for professional staff working in the government and to those working in the CYCCs. The repercussions from failing to adjust to these recommendations will inevitably lead to the employment of a remedial model of care.
- Full Text:
- Date Issued: 2014
Investigating student readiness for tertiary education
- Authors: Agherdien, Nuraan
- Date: 2014
- Subjects: College preparation programs -- South Africa , Students, Transfer of , College student orientation
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9390 , http://hdl.handle.net/10948/d1020593
- Description: Many tertiary institutions are confronted with the challenge of unprepared students. This epidemic is largely due to factors in and out of individuals‟ control. These factors include academic proficiency, course-student match, support and integration, financial stability, preparation, personal circumstances and engagement. The main objective of this study is therefore threefold: Firstly, to describe what student readiness entails; secondly to understand why there is a lack of readiness among first-year Human Resource Management students, and thirdly, to identify and improve upon interventions that prepare students for tertiary education. For this study student readiness refers to the ability of students to meet the basic requirements to successfully enrol for a course without remedial assistance and to successfully complete their studies in the recommended timeframe. The target population of this study focussed on students who registered on a full-time basis for the National Diploma in Human Resource Management for the academic year 2014 (n=117). A self-administered questionnaire was distributed to the students and an open-ended questionnaire additionally to the lecturers who teach first-year Human Resource Management students. The study was subjected to various statistical techniques such as Cronbach‟s alpha, t-tests, Pearson moment product correlation and Cohen‟s d. In doing so an improved insight into student readiness and success was developed. The main findings of the study indicated that there is a relationship between the type of schooling and readiness factors as statistical significance was noted. In addition, students who scored high on readiness factors were more likely to succeed in tertiary education. Moreover the number of interventions students is exposed to positively influence student readiness and success. This study has contributed to the body of knowledge which relates to the broader educational environment in South Africa and provides recommendations to address student readiness and success.
- Full Text:
- Date Issued: 2014
- Authors: Agherdien, Nuraan
- Date: 2014
- Subjects: College preparation programs -- South Africa , Students, Transfer of , College student orientation
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: vital:9390 , http://hdl.handle.net/10948/d1020593
- Description: Many tertiary institutions are confronted with the challenge of unprepared students. This epidemic is largely due to factors in and out of individuals‟ control. These factors include academic proficiency, course-student match, support and integration, financial stability, preparation, personal circumstances and engagement. The main objective of this study is therefore threefold: Firstly, to describe what student readiness entails; secondly to understand why there is a lack of readiness among first-year Human Resource Management students, and thirdly, to identify and improve upon interventions that prepare students for tertiary education. For this study student readiness refers to the ability of students to meet the basic requirements to successfully enrol for a course without remedial assistance and to successfully complete their studies in the recommended timeframe. The target population of this study focussed on students who registered on a full-time basis for the National Diploma in Human Resource Management for the academic year 2014 (n=117). A self-administered questionnaire was distributed to the students and an open-ended questionnaire additionally to the lecturers who teach first-year Human Resource Management students. The study was subjected to various statistical techniques such as Cronbach‟s alpha, t-tests, Pearson moment product correlation and Cohen‟s d. In doing so an improved insight into student readiness and success was developed. The main findings of the study indicated that there is a relationship between the type of schooling and readiness factors as statistical significance was noted. In addition, students who scored high on readiness factors were more likely to succeed in tertiary education. Moreover the number of interventions students is exposed to positively influence student readiness and success. This study has contributed to the body of knowledge which relates to the broader educational environment in South Africa and provides recommendations to address student readiness and success.
- Full Text:
- Date Issued: 2014
Urban agriculture for sustainable livelihood : a case study of migrants' women in Johannesburg
- Authors: Agho, Njenyuei Gideon
- Date: 2014
- Subjects: Urban agriculture -- Economic aspects -- South Africa -- Johannesburg , Agriculture -- Economic aspects -- South Africa , Rural-urban migration -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9228 , http://hdl.handle.net/10948/d1020980
- Description: This research examines how urban agriculture contributes to the sustainable livelihood of migrants’ women living in the inner city of Johannesburg. The study focuses on the Cameroonian women community living in Turffontein. It explores the significant process of migration into the Republic of South Africa and the inspiration behind the choice of urban agriculture in the inner city of Johannesburg by women. The research report assesses the impact of urban agriculture on sustainable livelihood in the life of Cameroonian women living in Turffontein. It also examines the constraints encountered by these Cameroonians women in Turffontein in the practice of urban agriculture for sustainable livelihood. The findings of this study reveal that urban agriculture is used as a strategy for sustainable livelihood to a lot of Cameroonian migrants’ women living in Turffontein. The study has also shown how through urban agriculture these migrants’ women have been able to raise substantial income to support their respective families both in South Africa and in Cameroon. The study is based on a purposeful sample of Cameroonian migrants’ women living in the inner city of Johannesburg practicing urban agriculture. It uses a mixed method of approach with a transect walk to the area where this women practice the urban agriculture. It also included an in-depth face to face interactive interview and written sources such as journals, books and research reports where combined to gather relevant data. Thematic content analysis was used to analyse the data.
- Full Text:
- Date Issued: 2014
- Authors: Agho, Njenyuei Gideon
- Date: 2014
- Subjects: Urban agriculture -- Economic aspects -- South Africa -- Johannesburg , Agriculture -- Economic aspects -- South Africa , Rural-urban migration -- South Africa
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9228 , http://hdl.handle.net/10948/d1020980
- Description: This research examines how urban agriculture contributes to the sustainable livelihood of migrants’ women living in the inner city of Johannesburg. The study focuses on the Cameroonian women community living in Turffontein. It explores the significant process of migration into the Republic of South Africa and the inspiration behind the choice of urban agriculture in the inner city of Johannesburg by women. The research report assesses the impact of urban agriculture on sustainable livelihood in the life of Cameroonian women living in Turffontein. It also examines the constraints encountered by these Cameroonians women in Turffontein in the practice of urban agriculture for sustainable livelihood. The findings of this study reveal that urban agriculture is used as a strategy for sustainable livelihood to a lot of Cameroonian migrants’ women living in Turffontein. The study has also shown how through urban agriculture these migrants’ women have been able to raise substantial income to support their respective families both in South Africa and in Cameroon. The study is based on a purposeful sample of Cameroonian migrants’ women living in the inner city of Johannesburg practicing urban agriculture. It uses a mixed method of approach with a transect walk to the area where this women practice the urban agriculture. It also included an in-depth face to face interactive interview and written sources such as journals, books and research reports where combined to gather relevant data. Thematic content analysis was used to analyse the data.
- Full Text:
- Date Issued: 2014
Assessment of the prevalence of faecal coliforms and Escherichia coli o157:h7 in the final effluents of two wastewater treatment plants in Amahlathi Local Municipality of Eastern Cape Province, South Africa
- Authors: Ajibade, Adefisoye Martins
- Date: 2014
- Subjects: Sewage disposal plants , Escherichia coli -- South Africa -- Eastern Cape , Escherichia coli O157:H7 , Escherichia coli , Effluent quality -- Testing , Whole effluent toxicity testing , Water -- Purification
- Language: English
- Type: Thesis , Masters , MSc (Microbiology)
- Identifier: vital:11283 , http://hdl.handle.net/10353/d1016166 , Sewage disposal plants , Escherichia coli -- South Africa -- Eastern Cape , Escherichia coli O157:H7 , Escherichia coli , Effluent quality -- Testing , Whole effluent toxicity testing , Water -- Purification
- Description: The production of final effluents that meet discharged requirements and guidelines remain a major challenge particularly in the developing world with the resultant problem of surface water pollution. This study assessed the physicochemical and microbiological qualities of two wastewater treatment works in the Eastern Cape Province of South Africa in terms of the prevalence of faecal coliforms and Escherichia coli O157:H7 over a five month period. All physicochemical and microbiological analyses were carried out using standard methods. Data were collected in triplicates and analysed statistically using IBM SPSS version 20.0. The ranges of some of the physicochemical parameters that complied with set guidelines include pH (6.7 – 7.6), TDS (107 – 171 mg/L), EC (168 – 266 μS/cm), Temperature (15 – 24oC), NO3- (0 – 8.2 mg/L), NO2- (0.14 – 0.71 mg/L) and PO4 (1.05 – 4.50 mg/L). Others including Turbidity (2.64 – 58.00 NTU), Free Cl (0.13 – 0.65 mg/L), DO (2.20 – 8.48 mg/L), BOD (0.13 – 6.85 mg/L) and COD (40 – 482 mg/L) did not comply with set guidelines. The microbiological parameters ranged 0 – 2.7 × 104 CFU/100 ml for FC and 0 – 9.3 × 103 for EHEC CFU/100 ml, an indication of non-compliance with set guidelines. Preliminary identification of 40 randomly selected presumptive enterohemorrhagic E. coli isolates by Gram’s staining and oxidase test shows 100% (all 40 selected isolates) to be Gram positive while 90% (36 randomly selected isolates) were oxidase negative. Statistical correlation between the physicochemical and the microbiological parameters were generally weak except in the case of free chlorine and DO where they showed inverse correlation with the microbiological parameters. The recovery of EHEC showed the inefficiency of the treatment processes to effectively inactivate the bacteria, and possibly other pathogenic bacteria that may be present in the treated wastewater. The assessment suggested the need for proper monitoring and a review of the treatment procedures used at these treatment works.
- Full Text:
- Date Issued: 2014
- Authors: Ajibade, Adefisoye Martins
- Date: 2014
- Subjects: Sewage disposal plants , Escherichia coli -- South Africa -- Eastern Cape , Escherichia coli O157:H7 , Escherichia coli , Effluent quality -- Testing , Whole effluent toxicity testing , Water -- Purification
- Language: English
- Type: Thesis , Masters , MSc (Microbiology)
- Identifier: vital:11283 , http://hdl.handle.net/10353/d1016166 , Sewage disposal plants , Escherichia coli -- South Africa -- Eastern Cape , Escherichia coli O157:H7 , Escherichia coli , Effluent quality -- Testing , Whole effluent toxicity testing , Water -- Purification
- Description: The production of final effluents that meet discharged requirements and guidelines remain a major challenge particularly in the developing world with the resultant problem of surface water pollution. This study assessed the physicochemical and microbiological qualities of two wastewater treatment works in the Eastern Cape Province of South Africa in terms of the prevalence of faecal coliforms and Escherichia coli O157:H7 over a five month period. All physicochemical and microbiological analyses were carried out using standard methods. Data were collected in triplicates and analysed statistically using IBM SPSS version 20.0. The ranges of some of the physicochemical parameters that complied with set guidelines include pH (6.7 – 7.6), TDS (107 – 171 mg/L), EC (168 – 266 μS/cm), Temperature (15 – 24oC), NO3- (0 – 8.2 mg/L), NO2- (0.14 – 0.71 mg/L) and PO4 (1.05 – 4.50 mg/L). Others including Turbidity (2.64 – 58.00 NTU), Free Cl (0.13 – 0.65 mg/L), DO (2.20 – 8.48 mg/L), BOD (0.13 – 6.85 mg/L) and COD (40 – 482 mg/L) did not comply with set guidelines. The microbiological parameters ranged 0 – 2.7 × 104 CFU/100 ml for FC and 0 – 9.3 × 103 for EHEC CFU/100 ml, an indication of non-compliance with set guidelines. Preliminary identification of 40 randomly selected presumptive enterohemorrhagic E. coli isolates by Gram’s staining and oxidase test shows 100% (all 40 selected isolates) to be Gram positive while 90% (36 randomly selected isolates) were oxidase negative. Statistical correlation between the physicochemical and the microbiological parameters were generally weak except in the case of free chlorine and DO where they showed inverse correlation with the microbiological parameters. The recovery of EHEC showed the inefficiency of the treatment processes to effectively inactivate the bacteria, and possibly other pathogenic bacteria that may be present in the treated wastewater. The assessment suggested the need for proper monitoring and a review of the treatment procedures used at these treatment works.
- Full Text:
- Date Issued: 2014
Teachers' perceptions of behavioural problems manifested by Grade 11 and 12 learners in three Namibian schools
- Authors: Akawa, Ester Anna Nelago
- Date: 2014
- Subjects: Education, Secondary -- Namibia School children -- Namibia -- Attitudes Learning disabilities -- Social aspects Behavior disorders in children -- Education (Secondary) -- Namibia Children with social disabilities -- Education (Secondary) -- Namibia Emotional problems of children -- Education (Secondary) -- Namibia Teachers -- Job stress -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1962 , http://hdl.handle.net/10962/d1010868
- Description: In Namibia today few learners with behavioural and learning problems are within special schools as most are placed within the mainstream school system. Placing these learners within the mainstream system is part of the policy of Inclusive Education (IE) because it argues that this would benefit these learners and also save resources. IE is concerned with addressing barriers to learning and behavioural problems are regarded as one of these barriers. IE argues for a series of new approaches to the diagnosis and response to learners with behavioural problems. This poses challenges for teachers in mainstream schools. Teachers are at the forefront of this situation as they are usually the first to observe and experience the behavioural problems in the schools and are expected to respond appropriately. They find this situation both challenging and problematic. This research explores a sample of teachers’ perceptions of learners’ behavioural problems. To collect in-depth information, this study followed a qualitative approach with a case study design. The data were collected through semi-structured interviews, supplemented with observation and document analysis. The study consisted of fifteen respondents: three principals, three teacher counsellors and nine teachers from the three selected schools. This study illuminates the types of behaviour that teachers encounter, the impact of these behaviours, the factors seen as contributing to these behaviours, and how teachers and the school system deal with these behaviours. In addition the study applies Bronfenbrenner’s bioecological model (1992) to explain how the behaviours manifested by Grade 11 and 12 learners, and identified as problematic by teachers, are part of an interconnected nested social system. The results from the study indicate the manifestation of behavioural problems to be common occurrences in secondary schools are evident, amongst others, through fighting, bullying, substance abuse, truancy, and disrespect of teachers and authority. The teachers pointed to the prevalence of these problems as well as the serious impact such problems have on these learners, their fellow learners, and on the teachers. The teachers identified a complex array of what they saw as contributing factors located within the school, peer groups, family and home circumstances, the local community, as well within the national education policy, the economy and society. The study points to some specific, as well as broader, lessons and opportunities for action both for those managing the education system at the national level and for schools and teachers.
- Full Text:
- Date Issued: 2014
- Authors: Akawa, Ester Anna Nelago
- Date: 2014
- Subjects: Education, Secondary -- Namibia School children -- Namibia -- Attitudes Learning disabilities -- Social aspects Behavior disorders in children -- Education (Secondary) -- Namibia Children with social disabilities -- Education (Secondary) -- Namibia Emotional problems of children -- Education (Secondary) -- Namibia Teachers -- Job stress -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1962 , http://hdl.handle.net/10962/d1010868
- Description: In Namibia today few learners with behavioural and learning problems are within special schools as most are placed within the mainstream school system. Placing these learners within the mainstream system is part of the policy of Inclusive Education (IE) because it argues that this would benefit these learners and also save resources. IE is concerned with addressing barriers to learning and behavioural problems are regarded as one of these barriers. IE argues for a series of new approaches to the diagnosis and response to learners with behavioural problems. This poses challenges for teachers in mainstream schools. Teachers are at the forefront of this situation as they are usually the first to observe and experience the behavioural problems in the schools and are expected to respond appropriately. They find this situation both challenging and problematic. This research explores a sample of teachers’ perceptions of learners’ behavioural problems. To collect in-depth information, this study followed a qualitative approach with a case study design. The data were collected through semi-structured interviews, supplemented with observation and document analysis. The study consisted of fifteen respondents: three principals, three teacher counsellors and nine teachers from the three selected schools. This study illuminates the types of behaviour that teachers encounter, the impact of these behaviours, the factors seen as contributing to these behaviours, and how teachers and the school system deal with these behaviours. In addition the study applies Bronfenbrenner’s bioecological model (1992) to explain how the behaviours manifested by Grade 11 and 12 learners, and identified as problematic by teachers, are part of an interconnected nested social system. The results from the study indicate the manifestation of behavioural problems to be common occurrences in secondary schools are evident, amongst others, through fighting, bullying, substance abuse, truancy, and disrespect of teachers and authority. The teachers pointed to the prevalence of these problems as well as the serious impact such problems have on these learners, their fellow learners, and on the teachers. The teachers identified a complex array of what they saw as contributing factors located within the school, peer groups, family and home circumstances, the local community, as well within the national education policy, the economy and society. The study points to some specific, as well as broader, lessons and opportunities for action both for those managing the education system at the national level and for schools and teachers.
- Full Text:
- Date Issued: 2014
Toward a culture of engagement: leveraging the enterprise social network
- Authors: Alistoun, Garth
- Date: 2014
- Subjects: Communication in organizations -- South Africa Business communication -- South Africa Social media -- South Africa -- Case studies Leadership -- South Africa -- Case studies Human capital -- Management Personnel management Organizational effectiveness
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1154 , http://hdl.handle.net/10962/d1010869
- Description: This research aims to provide a theory of enterprise social networking that generates and/or sustains a culture of employee engagement within a chosen South African private sector company. Based on an extensive review of interesting literature and the application of a grounded theory process in a chosen case, this research work provides a theory of enterprise social networking sustaining and growing employee engagement together with an explanatory theoretical framework that makes the theory more practical. Employee engagement is defined as “the harnessing of organisation member’s selves to their work roles; in engagement people employ and express themselves physically, cognitively, and emotionally during role performances.” This research regards employee engagement as a three part concept composed of a trait (personality/cognitive) aspect, a state (emotional) aspect, and a behavioural aspect. Research has shown that employee engagement has an unequivocal positive impact on business outcomes, such as profitability, business performance, employee retention and productivity. Employee engagement can be regarded as a culture if it is abundant within the organization’s employee population. Gatenby et al. (2009) propose that employee engagement is fostered by creating the desire and opportunity for employees to connect with colleagues, managers and the wider organisation. This standpoint is supported by Kular et al. (2008) who state that the “key drivers of employee engagement identified include communication, opportunities for employees to feed their views upward and thinking that their managers are committed to the organisation.” Further indicators of employee engagement include strong leadership (particularly in the form of servant leadership), accountability, a positive and open organisational culture, autonomy, and opportunities for development. One of the key facets of employee engagement is connection. A complementary definition of social media, an umbrella under which enterprise social networks fall, is that “(it) is more of a relationship channel, a connection channel. Each and every tweet, update, video, post, is a connection point to another human being. And it’s the other human being who will determine your worth to them.” Social media provides participants with access to a larger pool of resources and relationships than they would normally have access to. This enlarged relationship/resource pool is a result of expanding human and social capital enabled through social media tools. In order to produce a theory of enterprise social networking sustaining and growing a culture of employee engagement a rigorous grounded theory methodology coupled with a case study methodology was applied. The case study methodology was used to identify a suitable research site and interesting participants within the site while the grounded theory process was used to produce both qualitative and quantitative data sets in a suitability rigorous fashion. The corroborative data was then used to discover and define the emergent theory.
- Full Text:
- Date Issued: 2014
- Authors: Alistoun, Garth
- Date: 2014
- Subjects: Communication in organizations -- South Africa Business communication -- South Africa Social media -- South Africa -- Case studies Leadership -- South Africa -- Case studies Human capital -- Management Personnel management Organizational effectiveness
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1154 , http://hdl.handle.net/10962/d1010869
- Description: This research aims to provide a theory of enterprise social networking that generates and/or sustains a culture of employee engagement within a chosen South African private sector company. Based on an extensive review of interesting literature and the application of a grounded theory process in a chosen case, this research work provides a theory of enterprise social networking sustaining and growing employee engagement together with an explanatory theoretical framework that makes the theory more practical. Employee engagement is defined as “the harnessing of organisation member’s selves to their work roles; in engagement people employ and express themselves physically, cognitively, and emotionally during role performances.” This research regards employee engagement as a three part concept composed of a trait (personality/cognitive) aspect, a state (emotional) aspect, and a behavioural aspect. Research has shown that employee engagement has an unequivocal positive impact on business outcomes, such as profitability, business performance, employee retention and productivity. Employee engagement can be regarded as a culture if it is abundant within the organization’s employee population. Gatenby et al. (2009) propose that employee engagement is fostered by creating the desire and opportunity for employees to connect with colleagues, managers and the wider organisation. This standpoint is supported by Kular et al. (2008) who state that the “key drivers of employee engagement identified include communication, opportunities for employees to feed their views upward and thinking that their managers are committed to the organisation.” Further indicators of employee engagement include strong leadership (particularly in the form of servant leadership), accountability, a positive and open organisational culture, autonomy, and opportunities for development. One of the key facets of employee engagement is connection. A complementary definition of social media, an umbrella under which enterprise social networks fall, is that “(it) is more of a relationship channel, a connection channel. Each and every tweet, update, video, post, is a connection point to another human being. And it’s the other human being who will determine your worth to them.” Social media provides participants with access to a larger pool of resources and relationships than they would normally have access to. This enlarged relationship/resource pool is a result of expanding human and social capital enabled through social media tools. In order to produce a theory of enterprise social networking sustaining and growing a culture of employee engagement a rigorous grounded theory methodology coupled with a case study methodology was applied. The case study methodology was used to identify a suitable research site and interesting participants within the site while the grounded theory process was used to produce both qualitative and quantitative data sets in a suitability rigorous fashion. The corroborative data was then used to discover and define the emergent theory.
- Full Text:
- Date Issued: 2014
The origin of endorheic pans on the African erosion surface North of Grahamstown, South Africa
- Authors: Alistoun, Judith Robyn
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4775 , http://hdl.handle.net/10962/d1011048
- Description: Pans on the African Erosion Surface near Grahamstown are small features, which, perhaps due to their small size have been neglected by researchers. From the outset the striking difference of these pans relative to other pans in southern Africa, is that the host rock is silcrete, a highly resistant rock well known as being associated with deeply weathered plateaus. The dominant origin theory for pans in southern Africa was developed by Goudie and Thomas (1985), and focuses on mechanisms relating to erosion and deflation. This model does not fit in well with the pans that have formed on substrate that has largely been unaffected by erosion in recent geological history (thousands to 10 000 years). As such this study examined the role of prolonged chemical weathering of Dwyka Tillite, that has led to the formation of silcrete. The hypothesis was that such deep weathering is responsible for local scale volume changes, which have in turn led to the formation of a depression. The centre of the pan indicated the highest concentration of Al₂O₃ and kaolinite at mid depths, and their concentrations decreased vertically away from these depths, and laterally towards the margins of the pan. Similar results were noted for SiO₂, while CaO and MgO (and calcite and dolomite) were highest at mid depths along the margins of the pan, and decreased laterally toward the centre of the pan. Results indicated that there was a positive relationship in the centre of the pan between: - the degree of chemical weathering and volume losses, - relative elevation of the pan and volume changes. Geochemically and mineralogically, there was a link between the high concentrations of Ca and Mg carbonates and volume gains in the margin of the pans. It is proposed that transpiration of vegetation along the margin of the pan caused the lateral movement of solutes, and the selective exclusion of these solutes by plants was associated with carbonate precipitation, leading to the creation of local relief. These results provide evidence to suggest that weathering and precipitation processes occurring over geological time scales are responsible for minor scale relief features, whose origin has been mistakenly attributed to deflation processes occurring over hundreds to thousands of years.
- Full Text:
- Date Issued: 2014
- Authors: Alistoun, Judith Robyn
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4775 , http://hdl.handle.net/10962/d1011048
- Description: Pans on the African Erosion Surface near Grahamstown are small features, which, perhaps due to their small size have been neglected by researchers. From the outset the striking difference of these pans relative to other pans in southern Africa, is that the host rock is silcrete, a highly resistant rock well known as being associated with deeply weathered plateaus. The dominant origin theory for pans in southern Africa was developed by Goudie and Thomas (1985), and focuses on mechanisms relating to erosion and deflation. This model does not fit in well with the pans that have formed on substrate that has largely been unaffected by erosion in recent geological history (thousands to 10 000 years). As such this study examined the role of prolonged chemical weathering of Dwyka Tillite, that has led to the formation of silcrete. The hypothesis was that such deep weathering is responsible for local scale volume changes, which have in turn led to the formation of a depression. The centre of the pan indicated the highest concentration of Al₂O₃ and kaolinite at mid depths, and their concentrations decreased vertically away from these depths, and laterally towards the margins of the pan. Similar results were noted for SiO₂, while CaO and MgO (and calcite and dolomite) were highest at mid depths along the margins of the pan, and decreased laterally toward the centre of the pan. Results indicated that there was a positive relationship in the centre of the pan between: - the degree of chemical weathering and volume losses, - relative elevation of the pan and volume changes. Geochemically and mineralogically, there was a link between the high concentrations of Ca and Mg carbonates and volume gains in the margin of the pans. It is proposed that transpiration of vegetation along the margin of the pan caused the lateral movement of solutes, and the selective exclusion of these solutes by plants was associated with carbonate precipitation, leading to the creation of local relief. These results provide evidence to suggest that weathering and precipitation processes occurring over geological time scales are responsible for minor scale relief features, whose origin has been mistakenly attributed to deflation processes occurring over hundreds to thousands of years.
- Full Text:
- Date Issued: 2014
Assessing intrapreneurship in a pharmaceutical manufacturing firm in the Eastern Cape
- Authors: Allen, Kevin Ian
- Date: 2014
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8828 , http://hdl.handle.net/10948/d1019758
- Description: Continuous innovation in terms of products, processes, administration and structures is needed to compete effectively in the global markets of the 21st century. This continuous innovation within an existing firm can be described in terms of intrapreneurship. The extent to which intrapreneurship is practiced within a Pharmaceutical firm (Firm A) within the Eastern Cape is the main question addressed in the research conducted. The research conducted involved the collection of two data sets. The first set looked at the perceived intrapreneurial characteristics of employees and their superiors. The second data set involved an assessment of 13 constructs (Strong customer orientation; Entrepreneurial leadership; Resource availability and accessibility; Innovation and creativity / new ideas encouraged; Empowered teams / multi-disciplined teamwork and diversity; Tolerance for risk, mistakes and failure; Sponsors (champions); Discretionary time and work; Appropriate rewards and reinforcement; Flat organisational structure with open communication and strong sense of belonging; Vision and strategic intent; Continuous- and cross-functional learning; Management support) measuring the intrapreneurial climate within the firm. Research took place within Firm A via a survey questionnaire that measured intrapreneurial characteristics using a 20 question self and superior assessment. The intrapreneurial climate survey consisted of 68 statements, which were assessed using a likert scale. A census was used given that the firm size was 450 employees. Results for the intrapreneurial climate gave Cronbach alpha values of greater than 0.6 for all of the constructs thus proving reliability of the data. With regard to the intrapreneurial characteristics results indicated that superiors were perceived to have weak characteristics as opposed to self-assessments which indicated strong characteristics. Three intrapreneurial climate constructs (Tolerance for risk, mistakes and failure; Appropriate rewards and reinforcement and Flat organisational structure) had mean results between 1.5 and 2.5 indicating respondents are not satisfied and attention needs to be given to improvement initiatives. The remaining ten constructs had mean scores between 2.5 and 3.5 indicating that respondents are neutral to the statement, indicating that improvement is recommended. Inferential statistics did not find significant differences in all constructs for any of the demographic variables tested. From the research it was concluded that the level of intrapreneurship within firm A is poor and recommendations are given. Further research within the firm is recommended.
- Full Text:
- Date Issued: 2014
- Authors: Allen, Kevin Ian
- Date: 2014
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8828 , http://hdl.handle.net/10948/d1019758
- Description: Continuous innovation in terms of products, processes, administration and structures is needed to compete effectively in the global markets of the 21st century. This continuous innovation within an existing firm can be described in terms of intrapreneurship. The extent to which intrapreneurship is practiced within a Pharmaceutical firm (Firm A) within the Eastern Cape is the main question addressed in the research conducted. The research conducted involved the collection of two data sets. The first set looked at the perceived intrapreneurial characteristics of employees and their superiors. The second data set involved an assessment of 13 constructs (Strong customer orientation; Entrepreneurial leadership; Resource availability and accessibility; Innovation and creativity / new ideas encouraged; Empowered teams / multi-disciplined teamwork and diversity; Tolerance for risk, mistakes and failure; Sponsors (champions); Discretionary time and work; Appropriate rewards and reinforcement; Flat organisational structure with open communication and strong sense of belonging; Vision and strategic intent; Continuous- and cross-functional learning; Management support) measuring the intrapreneurial climate within the firm. Research took place within Firm A via a survey questionnaire that measured intrapreneurial characteristics using a 20 question self and superior assessment. The intrapreneurial climate survey consisted of 68 statements, which were assessed using a likert scale. A census was used given that the firm size was 450 employees. Results for the intrapreneurial climate gave Cronbach alpha values of greater than 0.6 for all of the constructs thus proving reliability of the data. With regard to the intrapreneurial characteristics results indicated that superiors were perceived to have weak characteristics as opposed to self-assessments which indicated strong characteristics. Three intrapreneurial climate constructs (Tolerance for risk, mistakes and failure; Appropriate rewards and reinforcement and Flat organisational structure) had mean results between 1.5 and 2.5 indicating respondents are not satisfied and attention needs to be given to improvement initiatives. The remaining ten constructs had mean scores between 2.5 and 3.5 indicating that respondents are neutral to the statement, indicating that improvement is recommended. Inferential statistics did not find significant differences in all constructs for any of the demographic variables tested. From the research it was concluded that the level of intrapreneurship within firm A is poor and recommendations are given. Further research within the firm is recommended.
- Full Text:
- Date Issued: 2014
An architecutre for the effective use of mobile devices in supporting contact learning
- Authors: Alnseerat, Nemr
- Date: 2014
- Subjects: Mobile communication systems in education , Educational technology
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10490 , http://hdl.handle.net/10948/d1020079
- Description: The features and capacities of mobile devices offer a wide range of significant opportunities for providing learning content in workplaces and educational institutions. This new approach of teaching, called mobile learning, allows for the delivery of learning content on the move at any time. Mobile learning supports learning by producing learning content to learners in a modern and acceptable way. The number of mobile learning applications has increased rapidly in educational environments. There are, however, limited mobile learning applications that take advantage of mobile devices to support contact learning in the classroom environment. The aim of this research was to design a mobile learning architecture to effectively support contact learning in the classroom. The researcher investigated the historical and theoretical background of mobile learning and reported these findings. This included an overview of existing mobile learning architectures. After identifying their limitations, the researcher designed the Contact Instruction Mobile Learning Architecture (CIMLA) to facilitate the use of mobile devices in the classroom. The researcher developed the LiveLearning prototype based on the proposed architecture as a proof of concept. He conducted a usability evaluation in order to determine the usability of LiveLearning. The results indicated that the LiveLearning prototype is effective in supporting contact learning in the classroom.
- Full Text:
- Date Issued: 2014
- Authors: Alnseerat, Nemr
- Date: 2014
- Subjects: Mobile communication systems in education , Educational technology
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10490 , http://hdl.handle.net/10948/d1020079
- Description: The features and capacities of mobile devices offer a wide range of significant opportunities for providing learning content in workplaces and educational institutions. This new approach of teaching, called mobile learning, allows for the delivery of learning content on the move at any time. Mobile learning supports learning by producing learning content to learners in a modern and acceptable way. The number of mobile learning applications has increased rapidly in educational environments. There are, however, limited mobile learning applications that take advantage of mobile devices to support contact learning in the classroom environment. The aim of this research was to design a mobile learning architecture to effectively support contact learning in the classroom. The researcher investigated the historical and theoretical background of mobile learning and reported these findings. This included an overview of existing mobile learning architectures. After identifying their limitations, the researcher designed the Contact Instruction Mobile Learning Architecture (CIMLA) to facilitate the use of mobile devices in the classroom. The researcher developed the LiveLearning prototype based on the proposed architecture as a proof of concept. He conducted a usability evaluation in order to determine the usability of LiveLearning. The results indicated that the LiveLearning prototype is effective in supporting contact learning in the classroom.
- Full Text:
- Date Issued: 2014
An investigation of the intention to leave or stay of health care professionals at St. Andrews Hospital
- Authors: Amanambu, Rochelle Aneeta
- Date: 2014
- Subjects: Medical personnel -- Job satisfaction -- South Africa -- Eastern Cape -- Case studies Medical personnel -- Job stress -- South Africa -- Eastern Cape -- Case studies Hospitals -- South Africa -- Eastern Cape -- Administration Hospitals -- Medical staff -- South Africa -- Eastern Cape Hospitals -- Officials and employees -- South Africa -- Eastern Cape -- Turnover Health services administration -- South Africa -- Eastern Cape Health planning -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:823 , http://hdl.handle.net/10962/d1011091
- Description: Background: The demand for and retention of talent worldwide is aggravated by revolutionary trends that include global competition, demographic changes and technological advances. In South Africa this phenomenon according to Frost (2002) is further challenged by the emigration of skilled people; the relative scarcity of specialist and managerial employees; employment equity and affirmative action procedures. But the development of strategies first requires an understanding of the factors which influence decisions to leave or stay particularly in rural and remote areas. St. Andrews Hospital is a rural district hospital in Ugu District, KZN. Its remoteness from urban areas and the lack of resources contributes towards challenges of attracting and retaining health care professionals to the area. It is the aim of this study to identify the ten most prevalent turnover and retention factors in a rural district hospital with the intention of making recommendations towards strategies to mitigate turnover and improve retention of health care professionals. This study will not only serve the local Human Resource Department but may also be used to inform district and provincial policies as well as departments’ decisions in the design or the review of current retention strategies aimed at reducing turnover. Method: The survey method was used to collect the primary data by distribution of self-administered questionnaires to Health Care Professionals at St. Andrews Hospital. Of the one hundred and fifty questionnaires distributed, one hundred and seven were returned (71% response rate) and formed the basis of the study. Results: Based on the impact scores, the top three turnover factors identified were, the way the organisation is led by top management (0.934); the size of the workload (0.862); and the way problems are dealt with by managers in the organisation (0.817). No statistically significant relationships were found between turnover factors and biographical variable. Availability of quality health services was ranked as the external factor that had the highest influence (78%) on turnover, while geographical location was ranked the lowest. The main reason given by respondents for leaving their previous employment was promotion, followed by distance and personal/family reasons. The top three retention factors identified from the impact scores were the quality of relationships with colleagues (1.698); the amount of support received from managers and colleagues (1.484); and the level of engagement and involvement with the job (1.390). This demonstrates that the salary package often thought to be a first priority factor Mobley, Horner and Hollingsworth (1978); Mobley (1982) and Herzberg (2003) is far less of a determining factor at St. Andrews Hospital than management support, job involvement and person-organisation fit as well as the social relationships formed in the workplace. A positive relationship was found between leadership and job dimension factors at the 1% level of significance. This supports the strong social bond (person-organisation fit) formed in the work environment between management and colleagues that supports retention and increases level of commitment. An important result of the study was that 46% of the respondents were thinking of leaving the town within the year while 29% were considering resigning from St. Andrews Hospital within the year. Conclusion: The results reveal a complex interaction of factors impacting on turnover and retention. The Human Resource Management function has a pivotal role to play in improving its ability to attract and retain professionals through developing comprehensive strategies based on external and internal and environmental factors. The study conveys to the St. Andrews Hospital management that turnover and retention factors are unique to the location and the working environment and differs amongst Health Care Professionals – this should be deliberated on when formulating Hospital Human Resource retention policies.
- Full Text:
- Date Issued: 2014
- Authors: Amanambu, Rochelle Aneeta
- Date: 2014
- Subjects: Medical personnel -- Job satisfaction -- South Africa -- Eastern Cape -- Case studies Medical personnel -- Job stress -- South Africa -- Eastern Cape -- Case studies Hospitals -- South Africa -- Eastern Cape -- Administration Hospitals -- Medical staff -- South Africa -- Eastern Cape Hospitals -- Officials and employees -- South Africa -- Eastern Cape -- Turnover Health services administration -- South Africa -- Eastern Cape Health planning -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:823 , http://hdl.handle.net/10962/d1011091
- Description: Background: The demand for and retention of talent worldwide is aggravated by revolutionary trends that include global competition, demographic changes and technological advances. In South Africa this phenomenon according to Frost (2002) is further challenged by the emigration of skilled people; the relative scarcity of specialist and managerial employees; employment equity and affirmative action procedures. But the development of strategies first requires an understanding of the factors which influence decisions to leave or stay particularly in rural and remote areas. St. Andrews Hospital is a rural district hospital in Ugu District, KZN. Its remoteness from urban areas and the lack of resources contributes towards challenges of attracting and retaining health care professionals to the area. It is the aim of this study to identify the ten most prevalent turnover and retention factors in a rural district hospital with the intention of making recommendations towards strategies to mitigate turnover and improve retention of health care professionals. This study will not only serve the local Human Resource Department but may also be used to inform district and provincial policies as well as departments’ decisions in the design or the review of current retention strategies aimed at reducing turnover. Method: The survey method was used to collect the primary data by distribution of self-administered questionnaires to Health Care Professionals at St. Andrews Hospital. Of the one hundred and fifty questionnaires distributed, one hundred and seven were returned (71% response rate) and formed the basis of the study. Results: Based on the impact scores, the top three turnover factors identified were, the way the organisation is led by top management (0.934); the size of the workload (0.862); and the way problems are dealt with by managers in the organisation (0.817). No statistically significant relationships were found between turnover factors and biographical variable. Availability of quality health services was ranked as the external factor that had the highest influence (78%) on turnover, while geographical location was ranked the lowest. The main reason given by respondents for leaving their previous employment was promotion, followed by distance and personal/family reasons. The top three retention factors identified from the impact scores were the quality of relationships with colleagues (1.698); the amount of support received from managers and colleagues (1.484); and the level of engagement and involvement with the job (1.390). This demonstrates that the salary package often thought to be a first priority factor Mobley, Horner and Hollingsworth (1978); Mobley (1982) and Herzberg (2003) is far less of a determining factor at St. Andrews Hospital than management support, job involvement and person-organisation fit as well as the social relationships formed in the workplace. A positive relationship was found between leadership and job dimension factors at the 1% level of significance. This supports the strong social bond (person-organisation fit) formed in the work environment between management and colleagues that supports retention and increases level of commitment. An important result of the study was that 46% of the respondents were thinking of leaving the town within the year while 29% were considering resigning from St. Andrews Hospital within the year. Conclusion: The results reveal a complex interaction of factors impacting on turnover and retention. The Human Resource Management function has a pivotal role to play in improving its ability to attract and retain professionals through developing comprehensive strategies based on external and internal and environmental factors. The study conveys to the St. Andrews Hospital management that turnover and retention factors are unique to the location and the working environment and differs amongst Health Care Professionals – this should be deliberated on when formulating Hospital Human Resource retention policies.
- Full Text:
- Date Issued: 2014
Voting and meaning in Hooggenoeg, Grahamstown : an audience's reception of Grocott's Mail's 2011 municipal election coverage
- Authors: Amzat, Ajibola Taofeek
- Date: 2014
- Subjects: Grocott's Mail (Grahamstown, South Africa) Local elections -- South Africa -- Grahamstown Elections -- South Africa Press and politics -- South Africa -- Grahamstown Journalism -- Objectivity -- South Africa -- Grahamstown Newspapers -- Objectivity Journalism -- Political aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:5970 , http://hdl.handle.net/10962/d1011729
- Description: This thesis examines the meanings that residents of the township of Hooggenoeg (in Grahamstown, in the Eastern Cape province of South Africa) made of the election coverage in the Grocott’s Mail newspaper during 2011 municipal elections in South Africa. In addition, this study also sought to understand the particular set of ‘normative roles’ played by the paper, both with reference to the well-established body of theory about the normative roles of journalism in a democracy, and in terms of the paper’s own conceptualisation of its role in the functioning of local democracy. Grocott’s Mail, the oldest independent newspaper in South Africa, provided extensive pre-election coverage, which included producing and distributing an unprecedented free edition of the paper. The paper also facilitated a town hall debate in order to encourage residents to vote, and empower them to make a more informed choice about their vote. Three qualitative research methods, namely qualitative content analysis, focus group interviews, and individual interviews were used to examine the relationship between the content provided by the paper and the audience’s process of ‘making sense’ and deriving meaning from the content provided. The study concludes that Grocott’s attempt to encourage democratic culture in Grahamstown, in keeping with the more ‘facilitative’ normative roles that the local media can play, was only partially successful. Much of the election reporting subordinated the voices of the ordinary people, and privileged reporting that focussed narrowly on the voting process, and which foregrounded the views of political parties. Overall this coverage largely failed to resonate with the Grocott’s readers who live in Hooggenoeg (a largely ‘coloured’ area of Grahamstown), whose key concerns in terms of their daily life – such as poverty, unemployment, crime, lack of services – seemed, to them, unaddressed by this election coverage and, consequently, was not as engaging or convincing as the publishers/editors had hoped it would be. It can be also argued that Grocott’s narrow conceptualisation of democracy as entailing only public participation in electoral processes failed to cater for how audiences can be made aware of how they can participate in governance beyond the election period.
- Full Text:
- Date Issued: 2014
- Authors: Amzat, Ajibola Taofeek
- Date: 2014
- Subjects: Grocott's Mail (Grahamstown, South Africa) Local elections -- South Africa -- Grahamstown Elections -- South Africa Press and politics -- South Africa -- Grahamstown Journalism -- Objectivity -- South Africa -- Grahamstown Newspapers -- Objectivity Journalism -- Political aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:5970 , http://hdl.handle.net/10962/d1011729
- Description: This thesis examines the meanings that residents of the township of Hooggenoeg (in Grahamstown, in the Eastern Cape province of South Africa) made of the election coverage in the Grocott’s Mail newspaper during 2011 municipal elections in South Africa. In addition, this study also sought to understand the particular set of ‘normative roles’ played by the paper, both with reference to the well-established body of theory about the normative roles of journalism in a democracy, and in terms of the paper’s own conceptualisation of its role in the functioning of local democracy. Grocott’s Mail, the oldest independent newspaper in South Africa, provided extensive pre-election coverage, which included producing and distributing an unprecedented free edition of the paper. The paper also facilitated a town hall debate in order to encourage residents to vote, and empower them to make a more informed choice about their vote. Three qualitative research methods, namely qualitative content analysis, focus group interviews, and individual interviews were used to examine the relationship between the content provided by the paper and the audience’s process of ‘making sense’ and deriving meaning from the content provided. The study concludes that Grocott’s attempt to encourage democratic culture in Grahamstown, in keeping with the more ‘facilitative’ normative roles that the local media can play, was only partially successful. Much of the election reporting subordinated the voices of the ordinary people, and privileged reporting that focussed narrowly on the voting process, and which foregrounded the views of political parties. Overall this coverage largely failed to resonate with the Grocott’s readers who live in Hooggenoeg (a largely ‘coloured’ area of Grahamstown), whose key concerns in terms of their daily life – such as poverty, unemployment, crime, lack of services – seemed, to them, unaddressed by this election coverage and, consequently, was not as engaging or convincing as the publishers/editors had hoped it would be. It can be also argued that Grocott’s narrow conceptualisation of democracy as entailing only public participation in electoral processes failed to cater for how audiences can be made aware of how they can participate in governance beyond the election period.
- Full Text:
- Date Issued: 2014
A comparative evolutionary approach to gum-feeding in Galago Moholi and Microcebus Griseorufus
- Authors: Andrews, Curswan Allan
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc (Zoology)
- Identifier: vital:11795 , http://hdl.handle.net/10353/d1019831
- Description: Gums are soluble plant exudates rich in complex carbohydrates. In primates, the consumption of gum (gummivory) has been described as a primitive, fall-back diet exhibited when other food sources become scarce, particularly during dry periods. In apparent support for this interpretation, gummivory is often observed in nocturnal strepsirhines (tooth-combed primates) believed to have retained many primitive features. The complex carbohydrates in gums, however, are also known to be difficult to digest, and require particular alimentary adaptations. The hypothesis of a primitive diet predicts that gummivorous strepsirhines should use homologous digestive strategies, while the presence of different digestive adaptations in different lineages would suggest convergent evolution. I compared the digestive adaptations to gummivory in two small strepsirhine taxa, African lesser bushbabies (Galago moholi) and Malagasy reddish-grey mouse lemurs (Microcebus griseorufus). Both taxa digest gum primarily by fermentation, and have enlarged caeca for this process, but only G. moholi has an ansa coli in which digestion can be continued. In captive feeding experiments, the faeces of wild-caught G. moholi and M. griseorufus showed no significant difference in their digestive efficiency of gum compared with a control food (banana), and the banana and gum samples showed no significant difference in nutrient concentration and overall composition. To gain a broader understanding of the origins of gummivory in strepsirhines, I used a phylogenetic method to reconstruct their dietary evolution. My results indicate that gummivory evolved convergently in several primate lineages, apparently in response to environmental hypervariability. I conducted biochemical analyses of the secondary compounds found in gums that are regularly consumed, and preliminary results show that Commiphora spp. have a number of compounds, while Acacia spp. show no such traces. The absence of secondary compounds from M. griseorufus faeces suggests that the animals have physiological means for either converting them into digestible products or detoxifying and excreting them in their urine. Finally, I compared the distribution patterns of G. moholi and M. griseorufus with climatic parameters; both study taxa inhabit regions in which the dry season is characterised by little to no rainfall, a drought that may persist for months. Similar climatic regions are occupied by other gum-feeders, including the marsupial gliders (Petauridae) of Australia.
- Full Text:
- Date Issued: 2014
- Authors: Andrews, Curswan Allan
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc (Zoology)
- Identifier: vital:11795 , http://hdl.handle.net/10353/d1019831
- Description: Gums are soluble plant exudates rich in complex carbohydrates. In primates, the consumption of gum (gummivory) has been described as a primitive, fall-back diet exhibited when other food sources become scarce, particularly during dry periods. In apparent support for this interpretation, gummivory is often observed in nocturnal strepsirhines (tooth-combed primates) believed to have retained many primitive features. The complex carbohydrates in gums, however, are also known to be difficult to digest, and require particular alimentary adaptations. The hypothesis of a primitive diet predicts that gummivorous strepsirhines should use homologous digestive strategies, while the presence of different digestive adaptations in different lineages would suggest convergent evolution. I compared the digestive adaptations to gummivory in two small strepsirhine taxa, African lesser bushbabies (Galago moholi) and Malagasy reddish-grey mouse lemurs (Microcebus griseorufus). Both taxa digest gum primarily by fermentation, and have enlarged caeca for this process, but only G. moholi has an ansa coli in which digestion can be continued. In captive feeding experiments, the faeces of wild-caught G. moholi and M. griseorufus showed no significant difference in their digestive efficiency of gum compared with a control food (banana), and the banana and gum samples showed no significant difference in nutrient concentration and overall composition. To gain a broader understanding of the origins of gummivory in strepsirhines, I used a phylogenetic method to reconstruct their dietary evolution. My results indicate that gummivory evolved convergently in several primate lineages, apparently in response to environmental hypervariability. I conducted biochemical analyses of the secondary compounds found in gums that are regularly consumed, and preliminary results show that Commiphora spp. have a number of compounds, while Acacia spp. show no such traces. The absence of secondary compounds from M. griseorufus faeces suggests that the animals have physiological means for either converting them into digestible products or detoxifying and excreting them in their urine. Finally, I compared the distribution patterns of G. moholi and M. griseorufus with climatic parameters; both study taxa inhabit regions in which the dry season is characterised by little to no rainfall, a drought that may persist for months. Similar climatic regions are occupied by other gum-feeders, including the marsupial gliders (Petauridae) of Australia.
- Full Text:
- Date Issued: 2014