Investigation of photophysicochemical properties of zinc phthalocyanines conjugated to metallic nanoparticles
- Dube, Edith, Nwaji, Njemuwa, Oluwole, David O, Mack, John, Nyokong, Tebello
- Authors: Dube, Edith , Nwaji, Njemuwa , Oluwole, David O , Mack, John , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233425 , vital:50089 , xlink:href="https://doi.org/10.1016/j.jphotochem.2017.09.020"
- Description: The syntheses of zinc(II) tetra–[3–(4–phenoxy) (propanoic acid) phthalocyanine] (2) and zinc(II) mono–[3–(4–phenoxy) (propanoic acid) phthalocyanine (3) are reported in this work. Compounds 2 and 3 were covalently linked to glutathione capped silver (AgNPs–GSH), gold (AuNPs–GSH) and silver-gold alloy (Ag3Au1NPs–GSH) nanoparticles (NPs) via an amide bond formation to afford the conjugates: 2–AgNPs–GSH, 3–AgNPs–GSH, 2–AuNPs–GSH, 3–AuNPs–GSH, 2-Ag3Au1NPs–GSH and 3-Ag3Au1NPs–GSH. The photophysicochemical behaviours of the compounds and their conjugates with NPs were assessed in solution. The conjugates afforded a decrease in fluorescence quantum yields and lifetimes with improved triplet quantum yields in comparison to the compounds. Accordingly, the AgNPs and AuNPs conjugates with the compounds afforded high singlet quantum yields. On the contrary, the conjugates of the alloy afforded decreased singlet quantum yields probably due to the screening effect. The compounds and their conjugates with NPs could serve as a viable and efficacious photosensitizer for photodynamic therapy.
- Full Text:
- Date Issued: 2017
- Authors: Dube, Edith , Nwaji, Njemuwa , Oluwole, David O , Mack, John , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233425 , vital:50089 , xlink:href="https://doi.org/10.1016/j.jphotochem.2017.09.020"
- Description: The syntheses of zinc(II) tetra–[3–(4–phenoxy) (propanoic acid) phthalocyanine] (2) and zinc(II) mono–[3–(4–phenoxy) (propanoic acid) phthalocyanine (3) are reported in this work. Compounds 2 and 3 were covalently linked to glutathione capped silver (AgNPs–GSH), gold (AuNPs–GSH) and silver-gold alloy (Ag3Au1NPs–GSH) nanoparticles (NPs) via an amide bond formation to afford the conjugates: 2–AgNPs–GSH, 3–AgNPs–GSH, 2–AuNPs–GSH, 3–AuNPs–GSH, 2-Ag3Au1NPs–GSH and 3-Ag3Au1NPs–GSH. The photophysicochemical behaviours of the compounds and their conjugates with NPs were assessed in solution. The conjugates afforded a decrease in fluorescence quantum yields and lifetimes with improved triplet quantum yields in comparison to the compounds. Accordingly, the AgNPs and AuNPs conjugates with the compounds afforded high singlet quantum yields. On the contrary, the conjugates of the alloy afforded decreased singlet quantum yields probably due to the screening effect. The compounds and their conjugates with NPs could serve as a viable and efficacious photosensitizer for photodynamic therapy.
- Full Text:
- Date Issued: 2017
Investigation of the potency of topical corticosteroids using the vasoconstrictor assay
- Authors: Zvidzayi, Kudzayi Michael
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65279 , vital:28717
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
- Authors: Zvidzayi, Kudzayi Michael
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65279 , vital:28717
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
Investigation on the nature of records management in the office of the Premier Supply Chain management
- Authors: Vakalisa, Ndileka
- Date: 2017
- Subjects: Grahamstown (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27606 , vital:69319
- Description: The purpose of the study was to investigate on the nature of records management in the office of the Premier Supply Chain Management. This study focuses on the Supply Chain Unit in the office of the Premier in the Eastern Cape Province of South Africa. The study sought to investigate the classification systems in place that is records management policy, procedure manual and file plans. The legal framework that regulates archives. Data was collected using open-ended questionnaire. The target population of this study included all the officials within the Office of the Premier. The sample of 15 was derived from the supply chain management officials, records management managers and directors. The study adopted a qualitative research methodology, which is multimethod in its orientation, which involves an interpretative, naturalistic emphasis to its subject issue. Findings from the study revealed that the unit had its internal records management policy, an official framework document that outlined the processes involved in organising records within the department. Thus, there are policy frameworks within the department even though not clearly described to other employees, which might lead to risks in the management of records. The study also revealed that most records personnel were not trained to effectively manage records. It was also indicated that there is a lack of proper filing system and or electronic records management system. Hence, for effective and efficient records management, the study recommends the creation of a web-based integrated system for communication and where records can be accessed within one system. The study also recommends proper training of records personnel to mitigate risks. Hence, the study recommends that senior management create and implement a records management program that clearly outlines the procedures of records management, risks factors and how to minimize them. This will aide in good practice, uniformity, standardization, high levels of professionalism, accountability, and transparency. , Thesis (MLIS) -- Faculty of Social Sciences and Humanities, 2017
- Full Text:
- Date Issued: 2017
- Authors: Vakalisa, Ndileka
- Date: 2017
- Subjects: Grahamstown (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27606 , vital:69319
- Description: The purpose of the study was to investigate on the nature of records management in the office of the Premier Supply Chain Management. This study focuses on the Supply Chain Unit in the office of the Premier in the Eastern Cape Province of South Africa. The study sought to investigate the classification systems in place that is records management policy, procedure manual and file plans. The legal framework that regulates archives. Data was collected using open-ended questionnaire. The target population of this study included all the officials within the Office of the Premier. The sample of 15 was derived from the supply chain management officials, records management managers and directors. The study adopted a qualitative research methodology, which is multimethod in its orientation, which involves an interpretative, naturalistic emphasis to its subject issue. Findings from the study revealed that the unit had its internal records management policy, an official framework document that outlined the processes involved in organising records within the department. Thus, there are policy frameworks within the department even though not clearly described to other employees, which might lead to risks in the management of records. The study also revealed that most records personnel were not trained to effectively manage records. It was also indicated that there is a lack of proper filing system and or electronic records management system. Hence, for effective and efficient records management, the study recommends the creation of a web-based integrated system for communication and where records can be accessed within one system. The study also recommends proper training of records personnel to mitigate risks. Hence, the study recommends that senior management create and implement a records management program that clearly outlines the procedures of records management, risks factors and how to minimize them. This will aide in good practice, uniformity, standardization, high levels of professionalism, accountability, and transparency. , Thesis (MLIS) -- Faculty of Social Sciences and Humanities, 2017
- Full Text:
- Date Issued: 2017
Ionospheric disturbances during magnetic storms at SANAE
- Authors: Hiyadutuje, Alicreance
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/54956 , vital:26639
- Description: The coronal mass ejections (CMEs) and solar flares associated with extreme solar activity may strike the Earth's magnetosphere and give rise to geomagnetic storms. During geomagnetic storms, the polar plasma dynamics may influence the middle and low-latitude ionosphere via travelling ionospheric disturbances (TIDs). These are wave-like electron density disturbances caused by atmospheric gravity waves propagating in the ionosphere. TIDs focus and defocus SuperDARN signals producing a characteristic pattern of ground backscattered power (Samson et al., 1989). Geomagnetic storms may cause a decrease of total electron content (TEC), i.e. a negative storm effect, or/and an increase of TEC, i.e. a positive storm effect. The aim of this project was to investigate the ionospheric response to strong storms (Dst < -100 nT) between 2011 and 2015, using TEC and scintillation measurements derived from GPS receivers as well as SuperDARN power, Doppler velocity and convection maps. In this study the ionosphere's response to geomagnetic storms is determined by the magnitude and time of occurrence of the geomagnetic storm. The ionospheric TEC results of this study show that most of the storm effects observed were a combination of both negative and positive per storm per station (77.8%), and only 8.9% and 13.3% of effects on TEC were negative and positive respectively. The highest number of storm effects occurred in autumn (36.4%), while 31.6%, 28.4% and 3.6% occurred in winter, spring and summer respectively. During the storms studied, 71.4% had phase scintillation in the range of 0.7 - 1 radians, and only 14.3% of the storms had amplitude scintillations near 0.4. The storms studied at SANAE station generated TIDs with periods of less than an hour and amplitudes in the range 0.2 - 5 TECU. These TIDs were found to originate from the high-velocity plasma flows, some of which are visible in SuperDARN convection maps. Early studies concluded that likely sources of these disturbances correspond to ionospheric current surges (Bristow et al., 1994) in the dayside auroral zone (Huang et al., 1998).
- Full Text:
- Date Issued: 2017
- Authors: Hiyadutuje, Alicreance
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/54956 , vital:26639
- Description: The coronal mass ejections (CMEs) and solar flares associated with extreme solar activity may strike the Earth's magnetosphere and give rise to geomagnetic storms. During geomagnetic storms, the polar plasma dynamics may influence the middle and low-latitude ionosphere via travelling ionospheric disturbances (TIDs). These are wave-like electron density disturbances caused by atmospheric gravity waves propagating in the ionosphere. TIDs focus and defocus SuperDARN signals producing a characteristic pattern of ground backscattered power (Samson et al., 1989). Geomagnetic storms may cause a decrease of total electron content (TEC), i.e. a negative storm effect, or/and an increase of TEC, i.e. a positive storm effect. The aim of this project was to investigate the ionospheric response to strong storms (Dst < -100 nT) between 2011 and 2015, using TEC and scintillation measurements derived from GPS receivers as well as SuperDARN power, Doppler velocity and convection maps. In this study the ionosphere's response to geomagnetic storms is determined by the magnitude and time of occurrence of the geomagnetic storm. The ionospheric TEC results of this study show that most of the storm effects observed were a combination of both negative and positive per storm per station (77.8%), and only 8.9% and 13.3% of effects on TEC were negative and positive respectively. The highest number of storm effects occurred in autumn (36.4%), while 31.6%, 28.4% and 3.6% occurred in winter, spring and summer respectively. During the storms studied, 71.4% had phase scintillation in the range of 0.7 - 1 radians, and only 14.3% of the storms had amplitude scintillations near 0.4. The storms studied at SANAE station generated TIDs with periods of less than an hour and amplitudes in the range 0.2 - 5 TECU. These TIDs were found to originate from the high-velocity plasma flows, some of which are visible in SuperDARN convection maps. Early studies concluded that likely sources of these disturbances correspond to ionospheric current surges (Bristow et al., 1994) in the dayside auroral zone (Huang et al., 1998).
- Full Text:
- Date Issued: 2017
IsiXhosa dictionaries, language learning and intercultural communication
- Authors: Nkomo, Dion
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/468283 , vital:77039 , ISBN 9781776140275 , https://muse.jhu.edu/book/52741
- Description: To date, there has been no published textbook which takes into account changing sociolinguistic dynamics that have influenced South African society. Multilingualism and Intercultural Communication breaks new ground in this arena. Its scope ranges from macro-sociolinguistic questions pertaining to language policies and their implementation (or non-implementation), to micro-sociolinguistic observations of actual language-use in verbal interaction, mainly in multilingual contexts of Higher Education (HE). There is a gradual move for the study of language and culture to be taught in the context of (professional) disciplines in which they would be used, such as Journalism and African languages, Education and African languages, etc. The book caters for this growing market. Because of its multilingual nature, it caters to English and Afrikaans language speakers, as well as the Sotho and Nguni language groups. It brings together various inter-linked disciplines such as Sociolinguistics and Applied Language Studies, Media Studies and Journalism, History and Education, Social and Natural Sciences, Law, Human Language Technology, Music, Intercultural Communication and Literary Studies. The unique cross-cutting disciplinary features of the book will make it a must-have for twenty-first century South African students and scholars and those interested in applied language issues.
- Full Text:
- Date Issued: 2017
- Authors: Nkomo, Dion
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/468283 , vital:77039 , ISBN 9781776140275 , https://muse.jhu.edu/book/52741
- Description: To date, there has been no published textbook which takes into account changing sociolinguistic dynamics that have influenced South African society. Multilingualism and Intercultural Communication breaks new ground in this arena. Its scope ranges from macro-sociolinguistic questions pertaining to language policies and their implementation (or non-implementation), to micro-sociolinguistic observations of actual language-use in verbal interaction, mainly in multilingual contexts of Higher Education (HE). There is a gradual move for the study of language and culture to be taught in the context of (professional) disciplines in which they would be used, such as Journalism and African languages, Education and African languages, etc. The book caters for this growing market. Because of its multilingual nature, it caters to English and Afrikaans language speakers, as well as the Sotho and Nguni language groups. It brings together various inter-linked disciplines such as Sociolinguistics and Applied Language Studies, Media Studies and Journalism, History and Education, Social and Natural Sciences, Law, Human Language Technology, Music, Intercultural Communication and Literary Studies. The unique cross-cutting disciplinary features of the book will make it a must-have for twenty-first century South African students and scholars and those interested in applied language issues.
- Full Text:
- Date Issued: 2017
IsiXhosa ulwimi lwabantu abangesosininzi eZimbabwe: ukuphila nokulondolozwa kwaso
- Authors: Kunju, Hleze Welsh
- Date: 2017
- Subjects: Language policy Zimbabwe , Xhosa (African people) Zimbabwe , Xhosa (African people) Social life and customs Zimbabwe , Xhosa language Zimbabwe , Language spread , Culture diffusion
- Language: Xhosa
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/7370 , vital:21250
- Description: Kuqikelelwa ukuba kukho amaXhosa (amaMfengu) angcambu zawo ziseMzantsi Afrika amalunga namakhulu amabini amawaka azinze eZimbabwe ukususela kwiminyaka yoo-18001900. Uninzi lwawo lufumaneka eMbembesi, eFort Rixon, eFilabusi, eKenilworth naseMotapa eBubi. Imbali ithi, inxalenye yala maXhosa ngawaseMpuma Kapa, afudukela eZimbabwe noCecil John Rhodes eqhuba iinqwelo kananjalo esebenzela uRhodes ngeminyaka yoo-1800. Le thisisi yongeza kulwazi olutsha malunga nala maXhosa aseZimbabwe, iphonononga ubume bolwimi, imbali nemvelaphi yala maXhosa azinze eZimbabwe lo gama ibonisa ukuba naphantsi kwayiphi na imeko, ulwimi luyakwazi ukuphila ngaphaya kwemida. Ulwimi nenkcubeko zingumtya nethunga, ngenxa yoko le thisisi yayame kakhulu kwinkcubeko. Iethinografi nembali yomlomo zisetyenziswe njengendlela okanye imethodi yokuqhuba olu phando. Iziphumo zolu phando zibonisa ukuba umhlaba, inkcubeko, iingoma, inkolo yobuKrestu, iincwadi ezingaphelelwa xesha zoncwadi lwesiXhosa, iteknoloji namakhasi onxibelelwano nomgaqo-siseko waseZimbabwe (2013) zibe zizixhobo ezidlale indima ebonakalayo ekulondolozeni nasekuphuhliseni isiXhosa eZimbabwe. Imiba ephathelele kumgaqo-nkqubo wesiXhosa eZimbabwe nayo iyaphononongwa, njengokuba isiXhosa ilulwimi oluthathwa njengolusesikweni eZimbabwe.Kusetyenziswa iithiyori ngeethiyori ezingobuni, kuquka nethiyori kaCollier (1997) apho abona ubuni njengolunamacala amabini; avowal kunye ne-ascription. Ubuni bamaXhosa aseZimbabwe buxoxwe ngokwayama kwi-avowal njengokuba uCollier (Ibid.) eyicacisa. Kwizindululo eziqulathwe kolu phando, kuboniswa ukuba ikho imfuneko yokuba iintsapho zaseZimbabwe zidityaniswe nezizalwane zazo eziseMzantsi Afrika. Ukufundiswa kwesiXhosa kwaneenzame zokusebenzisa isiXhosa njengolwimi lokufunda nokufundisa kwizikolo zamaXhosa ezikumabanga aphantsi kuyafuneka nako ukuba kuphandwe nzulu. , There are an estimated two hundred thousand South African amaXhosa who are mostly amaMfengu descendants living in Zimbabwe since the late 1800s-1900s. The majority are found in the areas of Mbembesi, Fort Rixon in Filabusi, Kenilworth and the Motapa area in Bubi. It is stated that some of the amaXhosa living in Zimbabwe came from the Eastern Cape with Cecil John Rhodes as domestic workers and on wagons during the 1800s. Therefore, this thesis provides new knowledge about amaXhosa living in Zimbabwe and gives an analysis of the sociolinguistic and historical background of the amaXhosa living in Zimbabwe while showing how a cross-border language can survive against all odds. The subject of culture has been dealt with as there is a reciprocal relationship between language and culture. Ethnography and Oral History have been used as methods for this research. The findings reveal that land, culture, songs, religion, South African Xhosa literature classic books, technology and social media, as well as the 2013 Zimbabwean constitution, are tools that have played a role in the survival and maintenance of isiXhosa in Zimbabwe. It also assesses Language Policy issues as isiXhosa is now an officially recognized language in Zimbabwe. Drawing on various theories on identity, including Collier’s (1997) understanding that identity is divided into avowal and ascription, the identity of the amaXhosa of Zimbabwe has been discussed in this thesis with an emphasis on avowal as discussed by Collier (Ibid.). Among other recommendations, this study further recommends that a research that looks at the reunion of the Zimbabwean amaXhosa with their South African relatives needs to be undertaken. It also recommends that the teaching of isiXhosa as well as attempts to make isiXhosa the Language of Learning and Teaching (LoLT) in the amaXhosa primary schools and pre-schools also needs to be researched further.
- Full Text:
- Date Issued: 2017
- Authors: Kunju, Hleze Welsh
- Date: 2017
- Subjects: Language policy Zimbabwe , Xhosa (African people) Zimbabwe , Xhosa (African people) Social life and customs Zimbabwe , Xhosa language Zimbabwe , Language spread , Culture diffusion
- Language: Xhosa
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/7370 , vital:21250
- Description: Kuqikelelwa ukuba kukho amaXhosa (amaMfengu) angcambu zawo ziseMzantsi Afrika amalunga namakhulu amabini amawaka azinze eZimbabwe ukususela kwiminyaka yoo-18001900. Uninzi lwawo lufumaneka eMbembesi, eFort Rixon, eFilabusi, eKenilworth naseMotapa eBubi. Imbali ithi, inxalenye yala maXhosa ngawaseMpuma Kapa, afudukela eZimbabwe noCecil John Rhodes eqhuba iinqwelo kananjalo esebenzela uRhodes ngeminyaka yoo-1800. Le thisisi yongeza kulwazi olutsha malunga nala maXhosa aseZimbabwe, iphonononga ubume bolwimi, imbali nemvelaphi yala maXhosa azinze eZimbabwe lo gama ibonisa ukuba naphantsi kwayiphi na imeko, ulwimi luyakwazi ukuphila ngaphaya kwemida. Ulwimi nenkcubeko zingumtya nethunga, ngenxa yoko le thisisi yayame kakhulu kwinkcubeko. Iethinografi nembali yomlomo zisetyenziswe njengendlela okanye imethodi yokuqhuba olu phando. Iziphumo zolu phando zibonisa ukuba umhlaba, inkcubeko, iingoma, inkolo yobuKrestu, iincwadi ezingaphelelwa xesha zoncwadi lwesiXhosa, iteknoloji namakhasi onxibelelwano nomgaqo-siseko waseZimbabwe (2013) zibe zizixhobo ezidlale indima ebonakalayo ekulondolozeni nasekuphuhliseni isiXhosa eZimbabwe. Imiba ephathelele kumgaqo-nkqubo wesiXhosa eZimbabwe nayo iyaphononongwa, njengokuba isiXhosa ilulwimi oluthathwa njengolusesikweni eZimbabwe.Kusetyenziswa iithiyori ngeethiyori ezingobuni, kuquka nethiyori kaCollier (1997) apho abona ubuni njengolunamacala amabini; avowal kunye ne-ascription. Ubuni bamaXhosa aseZimbabwe buxoxwe ngokwayama kwi-avowal njengokuba uCollier (Ibid.) eyicacisa. Kwizindululo eziqulathwe kolu phando, kuboniswa ukuba ikho imfuneko yokuba iintsapho zaseZimbabwe zidityaniswe nezizalwane zazo eziseMzantsi Afrika. Ukufundiswa kwesiXhosa kwaneenzame zokusebenzisa isiXhosa njengolwimi lokufunda nokufundisa kwizikolo zamaXhosa ezikumabanga aphantsi kuyafuneka nako ukuba kuphandwe nzulu. , There are an estimated two hundred thousand South African amaXhosa who are mostly amaMfengu descendants living in Zimbabwe since the late 1800s-1900s. The majority are found in the areas of Mbembesi, Fort Rixon in Filabusi, Kenilworth and the Motapa area in Bubi. It is stated that some of the amaXhosa living in Zimbabwe came from the Eastern Cape with Cecil John Rhodes as domestic workers and on wagons during the 1800s. Therefore, this thesis provides new knowledge about amaXhosa living in Zimbabwe and gives an analysis of the sociolinguistic and historical background of the amaXhosa living in Zimbabwe while showing how a cross-border language can survive against all odds. The subject of culture has been dealt with as there is a reciprocal relationship between language and culture. Ethnography and Oral History have been used as methods for this research. The findings reveal that land, culture, songs, religion, South African Xhosa literature classic books, technology and social media, as well as the 2013 Zimbabwean constitution, are tools that have played a role in the survival and maintenance of isiXhosa in Zimbabwe. It also assesses Language Policy issues as isiXhosa is now an officially recognized language in Zimbabwe. Drawing on various theories on identity, including Collier’s (1997) understanding that identity is divided into avowal and ascription, the identity of the amaXhosa of Zimbabwe has been discussed in this thesis with an emphasis on avowal as discussed by Collier (Ibid.). Among other recommendations, this study further recommends that a research that looks at the reunion of the Zimbabwean amaXhosa with their South African relatives needs to be undertaken. It also recommends that the teaching of isiXhosa as well as attempts to make isiXhosa the Language of Learning and Teaching (LoLT) in the amaXhosa primary schools and pre-schools also needs to be researched further.
- Full Text:
- Date Issued: 2017
Isolation, characterization and antiproliferative activity of new metabolites from the South African endemic red algal species Laurencia alfredensis
- Dziwornu, Godwin A, Caira, Mino R, de la Mare, Jo-Anne, Edkins, Adrienne L, Bolton, John J, Beukes, Denzil R, Sunassee, Suthananda N
- Authors: Dziwornu, Godwin A , Caira, Mino R , de la Mare, Jo-Anne , Edkins, Adrienne L , Bolton, John J , Beukes, Denzil R , Sunassee, Suthananda N
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59963 , vital:27715 , https://doi:10.3390/molecules22040513
- Description: The marine red algae of the genus Laurencia have been widely studied for their structurally diverse and biologically active secondary metabolites. We report here the natural product investigation of the organic extract of a newly identified South African endemic species, Laurencia alfredensis. A sequence of column chromatography, preparative TLC and normal phase HPLC resulted in the isolation of eleven compounds comprising three labdane-type diterpenes (1-3), four polyether triterpenes (4-7), three cholestane-type ecdysteroids (8-10) and a glycolipid (11). Compounds 1-3, 5-8 and 10 have not previously been reported, while compound 9 is reported here for the first time from a natural source and the known compound 11 isolated for the first time from the genus Laurencia. The structural elucidation and the relative configuration assignments of the compounds were accomplished by extensive use of ID- and 2D-NMR, HR-ESI-MS, UV and IR spectroscopic techniques, while the absolute configuration of compound 1 was determined by single-crystal X-ray diffraction analysis. All compounds were evaluated against the MDA-MB-231 breast and HeLa cervical cancer cell lines. Compound 2 exhibited low micromolar antiproliferative activity (IC50 = 9.3 gM) against the triple negative breast carcinoma and compound 7 was similarly active (IC50 = 8.8 gM) against the cervical cancer cell line.
- Full Text:
- Date Issued: 2017
- Authors: Dziwornu, Godwin A , Caira, Mino R , de la Mare, Jo-Anne , Edkins, Adrienne L , Bolton, John J , Beukes, Denzil R , Sunassee, Suthananda N
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59963 , vital:27715 , https://doi:10.3390/molecules22040513
- Description: The marine red algae of the genus Laurencia have been widely studied for their structurally diverse and biologically active secondary metabolites. We report here the natural product investigation of the organic extract of a newly identified South African endemic species, Laurencia alfredensis. A sequence of column chromatography, preparative TLC and normal phase HPLC resulted in the isolation of eleven compounds comprising three labdane-type diterpenes (1-3), four polyether triterpenes (4-7), three cholestane-type ecdysteroids (8-10) and a glycolipid (11). Compounds 1-3, 5-8 and 10 have not previously been reported, while compound 9 is reported here for the first time from a natural source and the known compound 11 isolated for the first time from the genus Laurencia. The structural elucidation and the relative configuration assignments of the compounds were accomplished by extensive use of ID- and 2D-NMR, HR-ESI-MS, UV and IR spectroscopic techniques, while the absolute configuration of compound 1 was determined by single-crystal X-ray diffraction analysis. All compounds were evaluated against the MDA-MB-231 breast and HeLa cervical cancer cell lines. Compound 2 exhibited low micromolar antiproliferative activity (IC50 = 9.3 gM) against the triple negative breast carcinoma and compound 7 was similarly active (IC50 = 8.8 gM) against the cervical cancer cell line.
- Full Text:
- Date Issued: 2017
Isolation, identification and genetic characterisation of a microsporidium isolated from carob moth, Ectomyelois ceratoniae (Zeller) (Lepidoptera: Pyralidae)
- Lloyd, Melissa, Knox, Caroline M, Hill, Martin P, Moore, Sean D, Thackeray, Sean R
- Authors: Lloyd, Melissa , Knox, Caroline M , Hill, Martin P , Moore, Sean D , Thackeray, Sean R
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59874 , vital:27674 , https://doi.org/10.4001/003.025.0529
- Description: 'Microsporidia' is a term used for organisms belonging to the phylum Microspora, which contains approximately 187 genera and 1500 species (Corradi 2015). They are obligate intracellular parasites with no active metabolic stages of the life cycle occurring outside of the host cells (Franzen & Muller 1999; Garcia 2002; Tsai et al. 2003; Huang et al. 2004). They exhibit eukaryotic characteristics such as a membrane-bound nucleus, an intracytoplasmic membrane system, and chromosome separation occurs on mitotic spindles. However, they also exhibit prokaryotic characteristics such as possession of a 70S ribosome, lack of true mitochondria and peroxisomes, a simple version of the Golgi apparatus, and a small genome which is much less complex than those of most eukaryotes (Franzen & Muller 1999; Garcia 2002). Microspo- ridia are parasitic in all major groups of animals, both vertebrates and invertebrates (Sprague 1977; Franzen & Muller 1999). Microsporidia were first recognised as pathogens in silkworms by Nageli (1857), and now have been found to infect many hosts such as humans, insects, fish and mammals (Stentiford et al. 2016).
- Full Text:
- Date Issued: 2017
- Authors: Lloyd, Melissa , Knox, Caroline M , Hill, Martin P , Moore, Sean D , Thackeray, Sean R
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59874 , vital:27674 , https://doi.org/10.4001/003.025.0529
- Description: 'Microsporidia' is a term used for organisms belonging to the phylum Microspora, which contains approximately 187 genera and 1500 species (Corradi 2015). They are obligate intracellular parasites with no active metabolic stages of the life cycle occurring outside of the host cells (Franzen & Muller 1999; Garcia 2002; Tsai et al. 2003; Huang et al. 2004). They exhibit eukaryotic characteristics such as a membrane-bound nucleus, an intracytoplasmic membrane system, and chromosome separation occurs on mitotic spindles. However, they also exhibit prokaryotic characteristics such as possession of a 70S ribosome, lack of true mitochondria and peroxisomes, a simple version of the Golgi apparatus, and a small genome which is much less complex than those of most eukaryotes (Franzen & Muller 1999; Garcia 2002). Microspo- ridia are parasitic in all major groups of animals, both vertebrates and invertebrates (Sprague 1977; Franzen & Muller 1999). Microsporidia were first recognised as pathogens in silkworms by Nageli (1857), and now have been found to infect many hosts such as humans, insects, fish and mammals (Stentiford et al. 2016).
- Full Text:
- Date Issued: 2017
Issues-Based Enquiry: An Enabling Pedagogy for ESD in Teacher Education and School Geography
- Authors: Wilmot, Diana P
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/436266 , vital:73253 , ISBN 978-3-319-45989-9 , https://doi.org/10.1007/978-3-319-45989-9_10
- Description: This chapter addresses the need for innovations in geography teacher education programmes in a developing world context. More specifically, it responds to the need for practical ‘how to’ examples for ESD integration into school geography by de-scribing a pedagogical experiment that was piloted with in-service Namibian teachers and education development offic-ers (EDOs) enrolled for a Bachelor of Education (Honours) de-gree in 2014. The theoretical constructs underpinning the ex-periment’s design and pedagogical approach as well as the teacher professional development model are described. This is followed by a description and justification of the methodology used to answer the research question: ‘How can issues-based enquiry enable the integration of ESD at the micro level of the classroom?’ The findings of the experiment provide evidence of how issues-based enquiry, underpinned by active learning and constructivist epistemology and a model of teacher pro-fessional development located in reflexive practice, enabled the teachers to acquire foundational knowledge and pedagog-ical content knowledge for effective integration of ESD into school geography. This chapter may offer other teacher educators some guidelines on how to develop teacher capacity to integrate ESD into their own programmes.
- Full Text:
- Date Issued: 2017
- Authors: Wilmot, Diana P
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/436266 , vital:73253 , ISBN 978-3-319-45989-9 , https://doi.org/10.1007/978-3-319-45989-9_10
- Description: This chapter addresses the need for innovations in geography teacher education programmes in a developing world context. More specifically, it responds to the need for practical ‘how to’ examples for ESD integration into school geography by de-scribing a pedagogical experiment that was piloted with in-service Namibian teachers and education development offic-ers (EDOs) enrolled for a Bachelor of Education (Honours) de-gree in 2014. The theoretical constructs underpinning the ex-periment’s design and pedagogical approach as well as the teacher professional development model are described. This is followed by a description and justification of the methodology used to answer the research question: ‘How can issues-based enquiry enable the integration of ESD at the micro level of the classroom?’ The findings of the experiment provide evidence of how issues-based enquiry, underpinned by active learning and constructivist epistemology and a model of teacher pro-fessional development located in reflexive practice, enabled the teachers to acquire foundational knowledge and pedagog-ical content knowledge for effective integration of ESD into school geography. This chapter may offer other teacher educators some guidelines on how to develop teacher capacity to integrate ESD into their own programmes.
- Full Text:
- Date Issued: 2017
Jah Hills
- Authors: Slasha, Unathi
- Date: 2017
- Language: English , Xhosa
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/7157 , vital:21222
- Description: Jah Hills is alone in Kwaf Indoda bush, waiting for elders to come, burn ibhuma and deliver him home. Two weeks before he departs from his initiation period, he is seduced by igqwirha. When he fails to satisfy her appetite, he gets ‘abducted and turned into isithunzela. One night, he narrowly escapes and finds his way back. But the experience at home is gruesome; they drive him away and want his death. My novel is fast paced, accumulating speed as it proceeds. It is formally experimental, drawing on forms that have gone before and trying to usher in a new manner of writing and looking at the world. It is told through the eyes of isithunzela that Jah Hills has become. It makes use of Nguni folklore, reimagined and subverted so it fits the character’s unearthly vision. Certain characters and moments from Nguni folktales are borrowed and appear throughout the text. Stylistically I draw extensively from the work of Sony Lab’ou Tansi, Taban Lo Liyong, Dambudzo Marechera, D.O. Fagunwa and Amos Tutuola.
- Full Text:
- Date Issued: 2017
- Authors: Slasha, Unathi
- Date: 2017
- Language: English , Xhosa
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/7157 , vital:21222
- Description: Jah Hills is alone in Kwaf Indoda bush, waiting for elders to come, burn ibhuma and deliver him home. Two weeks before he departs from his initiation period, he is seduced by igqwirha. When he fails to satisfy her appetite, he gets ‘abducted and turned into isithunzela. One night, he narrowly escapes and finds his way back. But the experience at home is gruesome; they drive him away and want his death. My novel is fast paced, accumulating speed as it proceeds. It is formally experimental, drawing on forms that have gone before and trying to usher in a new manner of writing and looking at the world. It is told through the eyes of isithunzela that Jah Hills has become. It makes use of Nguni folklore, reimagined and subverted so it fits the character’s unearthly vision. Certain characters and moments from Nguni folktales are borrowed and appear throughout the text. Stylistically I draw extensively from the work of Sony Lab’ou Tansi, Taban Lo Liyong, Dambudzo Marechera, D.O. Fagunwa and Amos Tutuola.
- Full Text:
- Date Issued: 2017
Job satisfaction, organisational justice in determining employee turnover among administrative staff at a university in South Africa
- Authors: Landu, Mzimkulu Christopher
- Date: 2017
- Subjects: Job satisfaction -- South Africa -- Eastern Cape Labor turnover -- South Africa -- Eastern Cape Universities and colleges -- South Africa -- Eastern Cape -- Employees
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10353/4784 , vital:28520
- Description: The aim of this study explore the role of job satisfaction , organizational justice in determining employee turnover among administrative staff at Walter Sisulu University at Ibika campus in Butterworth , in the Eastern Cape Province. A sample of 70 administrative staff was drawn for the population of 170. Results of the study indicated that the study variables are significantly and positively correlated with one another. Job satisfaction was found to be significantly and positively correlated with employee turnover. Organizational justice was also found to be significantly positively correlated with employee turnover. Likewise, a positive and significant relationship between job satisfaction and organizational justice was found. The findings of this study will assist Ibika campus management in reducing employee turnover and increase the retention of administrative staff at Ibika campus and the entire Walter Sisulu administrative staff at large.
- Full Text:
- Date Issued: 2017
- Authors: Landu, Mzimkulu Christopher
- Date: 2017
- Subjects: Job satisfaction -- South Africa -- Eastern Cape Labor turnover -- South Africa -- Eastern Cape Universities and colleges -- South Africa -- Eastern Cape -- Employees
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10353/4784 , vital:28520
- Description: The aim of this study explore the role of job satisfaction , organizational justice in determining employee turnover among administrative staff at Walter Sisulu University at Ibika campus in Butterworth , in the Eastern Cape Province. A sample of 70 administrative staff was drawn for the population of 170. Results of the study indicated that the study variables are significantly and positively correlated with one another. Job satisfaction was found to be significantly and positively correlated with employee turnover. Organizational justice was also found to be significantly positively correlated with employee turnover. Likewise, a positive and significant relationship between job satisfaction and organizational justice was found. The findings of this study will assist Ibika campus management in reducing employee turnover and increase the retention of administrative staff at Ibika campus and the entire Walter Sisulu administrative staff at large.
- Full Text:
- Date Issued: 2017
Journal development, scholar development and quality
- Rosenberg, Eureta, Togo, Muchaiteyi
- Authors: Rosenberg, Eureta , Togo, Muchaiteyi
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/67314 , vital:29072 , https://doi.org/10.4314/SAJEE.V.33I1.1
- Description: publisher version , In reflecting on the contributions to Volume 33, it is evident that a variety of theories about learning and social change inform the scholars in environmental education, ranging from behaviourist, to social behavioural, constructivist and social constructivist learning theories, social and critical realism, and more. What unites these papers is a shared concern about learning in relation to the future well-being of the planet and its people. New scholars entering the field of environmental and sustainability education have the task of mastering not only the social– ecological subject matter of the field, but also their chosen learning theories. In this regard, drawing on the back copies of the SAJEE can be of great value. Much research and writing has already been done on curriculum, education and learning inside and outside of formal institutions, yet many more questions remain. The field is best advanced by noting and building on, challenging and advancing past studies and existing scholarship. The fact that all 33 Volumes of the SAJEE are available online, just a ‘few clicks away’ from any student or supervisor with Internet access, is therefore an enormous boon. We encourage readers and future authors to draw on the work in this and other environmental education journals as they conceptualise, design and reflect on their own studies.
- Full Text:
- Date Issued: 2017
- Authors: Rosenberg, Eureta , Togo, Muchaiteyi
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/67314 , vital:29072 , https://doi.org/10.4314/SAJEE.V.33I1.1
- Description: publisher version , In reflecting on the contributions to Volume 33, it is evident that a variety of theories about learning and social change inform the scholars in environmental education, ranging from behaviourist, to social behavioural, constructivist and social constructivist learning theories, social and critical realism, and more. What unites these papers is a shared concern about learning in relation to the future well-being of the planet and its people. New scholars entering the field of environmental and sustainability education have the task of mastering not only the social– ecological subject matter of the field, but also their chosen learning theories. In this regard, drawing on the back copies of the SAJEE can be of great value. Much research and writing has already been done on curriculum, education and learning inside and outside of formal institutions, yet many more questions remain. The field is best advanced by noting and building on, challenging and advancing past studies and existing scholarship. The fact that all 33 Volumes of the SAJEE are available online, just a ‘few clicks away’ from any student or supervisor with Internet access, is therefore an enormous boon. We encourage readers and future authors to draw on the work in this and other environmental education journals as they conceptualise, design and reflect on their own studies.
- Full Text:
- Date Issued: 2017
JSON schema for attribute-based access control for network resource security
- Linklater, Gregory, Smith, Christian, Connan, James, Herbert, Alan, Irwin, Barry V W
- Authors: Linklater, Gregory , Smith, Christian , Connan, James , Herbert, Alan , Irwin, Barry V W
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428368 , vital:72506 , https://researchspace.csir.co.za/dspace/bitstream/handle/10204/9820/Linklater_19660_2017.pdf?sequence=1andisAllowed=y
- Description: Attribute-based Access Control (ABAC) is an access control model where authorization for an action on a resource is determined by evalu-ating attributes of the subject, resource (object) and environment. The attributes are evaluated against boolean rules of varying complexity. ABAC rule languages are often based on serializable object modeling and schema languages as in the case of XACML which is based on XML Schema. XACML is a standard by OASIS, and is the current de facto standard for ABAC. While a JSON profile for XACML exists, it is simply a compatibility layer for using JSON in XACML which caters to the XML object model paradigm, as opposed to the JSON object model paradigm. This research proposes JSON Schema as a modeling lan-guage that caters to the JSON object model paradigm on which to base an ABAC rule language. It continues to demonstrate its viability for the task by comparison against the features provided to XACML by XML Schema.
- Full Text:
- Date Issued: 2017
- Authors: Linklater, Gregory , Smith, Christian , Connan, James , Herbert, Alan , Irwin, Barry V W
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428368 , vital:72506 , https://researchspace.csir.co.za/dspace/bitstream/handle/10204/9820/Linklater_19660_2017.pdf?sequence=1andisAllowed=y
- Description: Attribute-based Access Control (ABAC) is an access control model where authorization for an action on a resource is determined by evalu-ating attributes of the subject, resource (object) and environment. The attributes are evaluated against boolean rules of varying complexity. ABAC rule languages are often based on serializable object modeling and schema languages as in the case of XACML which is based on XML Schema. XACML is a standard by OASIS, and is the current de facto standard for ABAC. While a JSON profile for XACML exists, it is simply a compatibility layer for using JSON in XACML which caters to the XML object model paradigm, as opposed to the JSON object model paradigm. This research proposes JSON Schema as a modeling lan-guage that caters to the JSON object model paradigm on which to base an ABAC rule language. It continues to demonstrate its viability for the task by comparison against the features provided to XACML by XML Schema.
- Full Text:
- Date Issued: 2017
Justin Davy of Burning Museum: an interview
- Authors: Dantas, Nancy
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147070 , vital:38590 , https://www.on-curating.org/issue-32-reader/justin-davy-of-the-burning-museum.html#.Xs0mCmgzbIU
- Description: The Burning Museum is an arts collective based in Cape Town, South Africa. This interview is the result of a three-part Skype conversation between Justin Davy of the Burning Museum and Nancy Dantas, an independent curator and researcher with an interest in recovering the neglected and overlooked exhibition histories and practices of the south.
- Full Text:
- Date Issued: 2017
- Authors: Dantas, Nancy
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147070 , vital:38590 , https://www.on-curating.org/issue-32-reader/justin-davy-of-the-burning-museum.html#.Xs0mCmgzbIU
- Description: The Burning Museum is an arts collective based in Cape Town, South Africa. This interview is the result of a three-part Skype conversation between Justin Davy of the Burning Museum and Nancy Dantas, an independent curator and researcher with an interest in recovering the neglected and overlooked exhibition histories and practices of the south.
- Full Text:
- Date Issued: 2017
Key factors behind the success of Somali owned spaza shops in Soweto
- Authors: Mini, Solomzi
- Date: 2017
- Subjects: Informal sector (Economics) -- South Africa -- Soweto Somalis -- South Africa -- Soweto
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/19393 , vital:28867
- Description: Informal retailing is a significant contributor to the South African economy in general and the retail sector specifically. It is a sector that is dominated by immigrant traders, while the numbers of local traders are shrinking by the day. The immigrant traders have outmaneuvered their local counterparts in this market through their ability to put together a compelling value proposition to the customers. Consequently, the focus of this research is to get a better understanding of the basis of their overall competitive advantage. Similar to previous research, this study concludes that the immigrant trader’s competitive advantage has competitive pricing as its foundation. However, this study had gone beyond the existing research which highlights competitive pricing as the reason for this success by suggesting that sound retailing principles which include good customer service, broader product range, hard work and lastly, a low cost business model are major contributors towards this success trend. All these elements combined together, put the immigrant traders in a strong position to dominate the market at the expense of the local traders. This study concludes by putting forward recommendations that can be implemented to support the local traders to compete effectively against their immigrant counterparts. The recommendations emphasis the importance of selecting and supporting traders who poses a good combination of all the qualities that are necessary for an entrepreneur to succeed, key among these being intrinsic motivation.
- Full Text:
- Date Issued: 2017
- Authors: Mini, Solomzi
- Date: 2017
- Subjects: Informal sector (Economics) -- South Africa -- Soweto Somalis -- South Africa -- Soweto
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/19393 , vital:28867
- Description: Informal retailing is a significant contributor to the South African economy in general and the retail sector specifically. It is a sector that is dominated by immigrant traders, while the numbers of local traders are shrinking by the day. The immigrant traders have outmaneuvered their local counterparts in this market through their ability to put together a compelling value proposition to the customers. Consequently, the focus of this research is to get a better understanding of the basis of their overall competitive advantage. Similar to previous research, this study concludes that the immigrant trader’s competitive advantage has competitive pricing as its foundation. However, this study had gone beyond the existing research which highlights competitive pricing as the reason for this success by suggesting that sound retailing principles which include good customer service, broader product range, hard work and lastly, a low cost business model are major contributors towards this success trend. All these elements combined together, put the immigrant traders in a strong position to dominate the market at the expense of the local traders. This study concludes by putting forward recommendations that can be implemented to support the local traders to compete effectively against their immigrant counterparts. The recommendations emphasis the importance of selecting and supporting traders who poses a good combination of all the qualities that are necessary for an entrepreneur to succeed, key among these being intrinsic motivation.
- Full Text:
- Date Issued: 2017
Key success factors for lean implementation in the Eastern Cape automotive industry
- Authors: Coetzer, Louis
- Date: 2017
- Subjects: Automobile industry and trade -- South Africa -- Eastern Cape , Automobile industry and trade -- Management , Manufacturing industries -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/14928 , vital:27909
- Description: Lean manufacturing has become an integral part of the global automotive industry where manufacturers strive to improve quality, reduce costs while providing customers with more variety. Organisations are implementing the Lean Production System (LPS) as a process improvement methodology to deliver their products faster, better quality and at a lower cost (Laureani & Antony, 2012). This is accomplished through the elimination of waste and continuous improvement (Kaizen). Through the effective implementation of lean principles, an organisation can realise cost competitiveness, process improvement and ultimately gain a competitive advantage. Although the theory of lean manufacturing is based on the implementation of tools, techniques and operational methods, many organisations that have implemented Lean have not reaped its full benefit. Thus, the realisation that lean manufacturing must consist of more than the summation of its operational based principles, tools and techniques. It has to be approached as a philosophy, which encompasses the entire organisation (Womack & Jones, 1996). Lean is a way of thinking and not merely the implementation of thoughts (Bhasin & Burcher, 2006). Laureani & Antony (2012) added that the fundamentals behind Lean are continuous improvement, waste elimination and employee empowerment. Lean introduction is more than the redesign of processes; the most important change must be in the knowledge of the employees (Dombrowski, Mielke & Engel, 2012). The literature clearly states that the successful implementation of a lean production system depends on more than the application of lean tools and techniques. Many authors and researchers hint that another critical factor associated with its implementation is the human aspect of the organisation. Hence, this study will examine the human related Key Success Factors (KSF‟s) required for the successful implementation of a lean system.
- Full Text:
- Date Issued: 2017
- Authors: Coetzer, Louis
- Date: 2017
- Subjects: Automobile industry and trade -- South Africa -- Eastern Cape , Automobile industry and trade -- Management , Manufacturing industries -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/14928 , vital:27909
- Description: Lean manufacturing has become an integral part of the global automotive industry where manufacturers strive to improve quality, reduce costs while providing customers with more variety. Organisations are implementing the Lean Production System (LPS) as a process improvement methodology to deliver their products faster, better quality and at a lower cost (Laureani & Antony, 2012). This is accomplished through the elimination of waste and continuous improvement (Kaizen). Through the effective implementation of lean principles, an organisation can realise cost competitiveness, process improvement and ultimately gain a competitive advantage. Although the theory of lean manufacturing is based on the implementation of tools, techniques and operational methods, many organisations that have implemented Lean have not reaped its full benefit. Thus, the realisation that lean manufacturing must consist of more than the summation of its operational based principles, tools and techniques. It has to be approached as a philosophy, which encompasses the entire organisation (Womack & Jones, 1996). Lean is a way of thinking and not merely the implementation of thoughts (Bhasin & Burcher, 2006). Laureani & Antony (2012) added that the fundamentals behind Lean are continuous improvement, waste elimination and employee empowerment. Lean introduction is more than the redesign of processes; the most important change must be in the knowledge of the employees (Dombrowski, Mielke & Engel, 2012). The literature clearly states that the successful implementation of a lean production system depends on more than the application of lean tools and techniques. Many authors and researchers hint that another critical factor associated with its implementation is the human aspect of the organisation. Hence, this study will examine the human related Key Success Factors (KSF‟s) required for the successful implementation of a lean system.
- Full Text:
- Date Issued: 2017
Kikuyu male teachers’ constructions of manhood in Nyandarua county, Kenya: implications for HIV and AIDS education
- Authors: Karanja, Ann Waithera
- Date: 2017
- Subjects: Teachers -- Kenya -- Attitudes , HIV (Viruses) -- Study and teaching -- Kenya AIDS (Disease) -- Study and teaching -- Kenya Kikuyu (African people) -- Study and teaching -- Kenya Men in education -- Kenya
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/17702 , vital:28438
- Description: The HIV and AIDS epidemic continues to ravage communities worldwide and is a major crisis particularly in Kenya, the fourth highly affected country in the world in terms of the number of people living with HIV. There is therefore an urgent need in Kenya to reduce HIV infections and educational systems have been identified as best placed to do so. In spite of having HIV and AIDS educational interventions, youths in Kenya still remain at the highest risk of HIV infection. There is therefore a need for more effective educational programmes that address socio-cultural beliefs and practices to be realized. It is also critical to understand how gender identities particularly, masculinity constructions play out in teachers’ identity formations and classroom dynamics. This study was conducted in Nyandarua County, Kenya and explores the implications of Kikuyu male rural secondary school teachers’ constructions of manhood on their teaching of sexuality education within the HIV and AIDS education curriculum. This qualitative study was framed within the constructivist paradigm and draws on a phenomenological design. Eighteen Kikuyu male teachers from six different schools were purposively selected. The data was generated by use of drawings, memory work and focus group discussion, and was analysed using thematic analysis. Ethical measures were adhered to and trustworthiness was ensured throughout the study. The Cultural Historical Activity Theory (CHAT) was used as the methodological and analytical tool for this study. The results of the study revealed that the constructions of masculinity amongst the Kikuyu male rural secondary school teachers involved in the study were deeply embedded into the Kikuyu socio-cultural beliefs and practices. This then influenced how they mediate their masculinities and experience themselves as men, as sexual beings and as teachers. The study also revealed that the teachers bring to the classroom internalised masculinity constructions acquired through interaction with the socio-cultural context. This in turn influences what is taught in HIV and AIDS education classes, and how it is taught. The study concludes that socio-cultural gender formations do shape the assertiveness and the self-efficacy of teachers in teaching about sexuality and HIV and AIDS. This suggests that HIV and AIDS intervention programmes should pay attention to socio-cultural beliefs and practices and be locally, culturally and contextually situated. This also calls for effective and sustainable teacher training, for teachers to be able to reflect upon their own attitudes, feelings, beliefs, experiences and behaviours and teach in ways that contribute to the fight against HIV transmission.
- Full Text:
- Date Issued: 2017
- Authors: Karanja, Ann Waithera
- Date: 2017
- Subjects: Teachers -- Kenya -- Attitudes , HIV (Viruses) -- Study and teaching -- Kenya AIDS (Disease) -- Study and teaching -- Kenya Kikuyu (African people) -- Study and teaching -- Kenya Men in education -- Kenya
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/17702 , vital:28438
- Description: The HIV and AIDS epidemic continues to ravage communities worldwide and is a major crisis particularly in Kenya, the fourth highly affected country in the world in terms of the number of people living with HIV. There is therefore an urgent need in Kenya to reduce HIV infections and educational systems have been identified as best placed to do so. In spite of having HIV and AIDS educational interventions, youths in Kenya still remain at the highest risk of HIV infection. There is therefore a need for more effective educational programmes that address socio-cultural beliefs and practices to be realized. It is also critical to understand how gender identities particularly, masculinity constructions play out in teachers’ identity formations and classroom dynamics. This study was conducted in Nyandarua County, Kenya and explores the implications of Kikuyu male rural secondary school teachers’ constructions of manhood on their teaching of sexuality education within the HIV and AIDS education curriculum. This qualitative study was framed within the constructivist paradigm and draws on a phenomenological design. Eighteen Kikuyu male teachers from six different schools were purposively selected. The data was generated by use of drawings, memory work and focus group discussion, and was analysed using thematic analysis. Ethical measures were adhered to and trustworthiness was ensured throughout the study. The Cultural Historical Activity Theory (CHAT) was used as the methodological and analytical tool for this study. The results of the study revealed that the constructions of masculinity amongst the Kikuyu male rural secondary school teachers involved in the study were deeply embedded into the Kikuyu socio-cultural beliefs and practices. This then influenced how they mediate their masculinities and experience themselves as men, as sexual beings and as teachers. The study also revealed that the teachers bring to the classroom internalised masculinity constructions acquired through interaction with the socio-cultural context. This in turn influences what is taught in HIV and AIDS education classes, and how it is taught. The study concludes that socio-cultural gender formations do shape the assertiveness and the self-efficacy of teachers in teaching about sexuality and HIV and AIDS. This suggests that HIV and AIDS intervention programmes should pay attention to socio-cultural beliefs and practices and be locally, culturally and contextually situated. This also calls for effective and sustainable teacher training, for teachers to be able to reflect upon their own attitudes, feelings, beliefs, experiences and behaviours and teach in ways that contribute to the fight against HIV transmission.
- Full Text:
- Date Issued: 2017
Kinetic analysis and general features of thermoluminescence of B2O3-Li2O-ZnF2 glass
- Thomas, Sunil, Chithambo, Makaiko L
- Authors: Thomas, Sunil , Chithambo, Makaiko L
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/116154 , vital:34324 , https://doi.org/10.1016/j.radmeas.2017.03.038
- Description: The intention of this study is to explore the thermoluminescence of beta irradiated B2O3-Li2O-ZnF2 glass. The glow-curve corresponding to 200 Gy shows three peaks; two weak-intensity peaks at 60 and 243 °C and a more prominent one at 118 °C, when measured at 1 °C/s. The dose response of the main peak at 118 °C was found to be sublinear in the range 200–1000 Gy. Regarding the kinetic analysis of the main peak, the activation energy of the corresponding electron trap was evaluated as 0.96 eV and the frequency factor as ∼1011 s−1. It is proposed that the thermoluminescence in B2O3-Li2O-ZnF2 glass is due to recombination of electrons, thermally released from Zn+ ionic defect sites, with the holes at boron-oxygen hole centres.
- Full Text: false
- Date Issued: 2017
- Authors: Thomas, Sunil , Chithambo, Makaiko L
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/116154 , vital:34324 , https://doi.org/10.1016/j.radmeas.2017.03.038
- Description: The intention of this study is to explore the thermoluminescence of beta irradiated B2O3-Li2O-ZnF2 glass. The glow-curve corresponding to 200 Gy shows three peaks; two weak-intensity peaks at 60 and 243 °C and a more prominent one at 118 °C, when measured at 1 °C/s. The dose response of the main peak at 118 °C was found to be sublinear in the range 200–1000 Gy. Regarding the kinetic analysis of the main peak, the activation energy of the corresponding electron trap was evaluated as 0.96 eV and the frequency factor as ∼1011 s−1. It is proposed that the thermoluminescence in B2O3-Li2O-ZnF2 glass is due to recombination of electrons, thermally released from Zn+ ionic defect sites, with the holes at boron-oxygen hole centres.
- Full Text: false
- Date Issued: 2017
Knowledge and knower structures in relation to reproductive and sexual health in school curricula of Kenya and South Africa
- Authors: Chemwor, Ezekiel Kiplimo
- Date: 2017
- Subjects: Curriculum planning -- Kenya , Curriculum planning -- South Africa Education -- Study and teaching Reproductive health -- Study and teaching -- Kenya Reproductive health -- Study and teaching -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/14884 , vital:27893
- Description: This study investigates the Reproductive and Sexual Health (RSH) knowledge as recontextualised in the school curricula of Kenya and South Africa. It sets to provide a holistic view of RSH by bringing to the fore the underlying principles structuring the legitimation of RSH knowledge and knowing in both curricula. More importantly, it provides a deeper understanding of what RSH concepts have to be known and what kind of ideal learner is being projected in the two curricula. The study sets out to answer the following two research questions: How is knowledge related to RSH legitimated in the South African and Kenyan school curricula? How are knowers related to RSH legitimated in the South African and Kenyan school curricula? Being located in the Official Recontextualisation Field of Bernstein’s pedagogic device, this study uses Bernstein’s knowledge structure approach and Legitimation Code Theory: Specialisation as theoretical framework. LCT: Specialisation codes provided a means of developing external languages of description or translation devices to build a requisite analytical framework for revealing the knowledge-knower structures legitimated in the two curricula. The study employs a multi-site case study research design with RSH knowledge and knowers in school curriculum being the case, and Kenya and South Africa as the two sites in the case study. The purpose of looking at the curricula from both countries was not specifically to compare the contents of the curricula documents, but rather to enable broader consideration of the ways in which they position RSH knowledge. The study found that RSH, as an interdisciplinary concept, is faced by a tension in its knowledge-knower structure across the curriculum levels. The biological component of the RSH concepts, has a hierarchical knowledge structure with a knowledge code that exhibited a purist insight as well as a horizontal knower structure that embodied a trained gaze, while the psychological component has a horizontal knowledge structure with a hierarchical knower structure that embodied a cultivated gaze.
- Full Text:
- Date Issued: 2017
- Authors: Chemwor, Ezekiel Kiplimo
- Date: 2017
- Subjects: Curriculum planning -- Kenya , Curriculum planning -- South Africa Education -- Study and teaching Reproductive health -- Study and teaching -- Kenya Reproductive health -- Study and teaching -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/14884 , vital:27893
- Description: This study investigates the Reproductive and Sexual Health (RSH) knowledge as recontextualised in the school curricula of Kenya and South Africa. It sets to provide a holistic view of RSH by bringing to the fore the underlying principles structuring the legitimation of RSH knowledge and knowing in both curricula. More importantly, it provides a deeper understanding of what RSH concepts have to be known and what kind of ideal learner is being projected in the two curricula. The study sets out to answer the following two research questions: How is knowledge related to RSH legitimated in the South African and Kenyan school curricula? How are knowers related to RSH legitimated in the South African and Kenyan school curricula? Being located in the Official Recontextualisation Field of Bernstein’s pedagogic device, this study uses Bernstein’s knowledge structure approach and Legitimation Code Theory: Specialisation as theoretical framework. LCT: Specialisation codes provided a means of developing external languages of description or translation devices to build a requisite analytical framework for revealing the knowledge-knower structures legitimated in the two curricula. The study employs a multi-site case study research design with RSH knowledge and knowers in school curriculum being the case, and Kenya and South Africa as the two sites in the case study. The purpose of looking at the curricula from both countries was not specifically to compare the contents of the curricula documents, but rather to enable broader consideration of the ways in which they position RSH knowledge. The study found that RSH, as an interdisciplinary concept, is faced by a tension in its knowledge-knower structure across the curriculum levels. The biological component of the RSH concepts, has a hierarchical knowledge structure with a knowledge code that exhibited a purist insight as well as a horizontal knower structure that embodied a trained gaze, while the psychological component has a horizontal knowledge structure with a hierarchical knower structure that embodied a cultivated gaze.
- Full Text:
- Date Issued: 2017
Knowledge and practice of radiographers regarding infection control in radiology department in Malawi
- Nyirenda, Denis Charles Glad
- Authors: Nyirenda, Denis Charles Glad
- Date: 2017
- Subjects: Radiologic technologists , Radiography, Medical -- Practice Cross infection -- Prevention
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/47848 , vital:40387
- Description: Infection control is an essential cornerstone of clinical care at all healthcare settings. The changing pattern of infections emphasises the need for all healthcare workers, including radiographers, to implement and strictly adhere to standard infection control precautions (SICP) that will protect both patients and healthcare workers from healthcare associated infections (HAIs). However, implementing SICP can be difficult, especially if radiographers do not have adequate knowledge, and skilled practices, in infection control. As a practicing radiographer and a health educator, the researcher observed that there were discrepancies regarding implementation of SICP by radiographers in Malawi. No study has been conducted to explore and describe the knowledge and practices of radiographers regarding infection control in radiology departments in Malawi. There are also no infection control guidelines. These gaps led to this study being conducted. The aim of the study was to explore, and describe, knowledge and practices of radiographers regarding infection control in radiology departments in government referral hospitals in Malawi in order to develop a draft guideline for infection control to facilitate sound knowledge and practices of radiographers regarding infection control in these departments. The study took place in four government referral hospitals and followed a quantitative, exploratory, and descriptive design that was contextual in nature. The study was conducted in two phases. In the first one a self-administered questionnaire was used to explore and describe the knowledge and practices of radiographers regarding infection control in government referral hospitals in Malawi. The second one included the development of a draft guideline for infection control in order to facilitate sound knowledge and practices of radiographers regarding infection control in government referral hospitals in Malawi. In phase one, the research population consisted of 80 permanently employed radiographers. A census sampling method was used to select 62 respondents. The data were collected by means of a self-administered questionnaire that was developed based on a literature review. Some questions were adapted from an existing questionnaire. The questionnaire consisted of questions and statements. It had four parts: demographic information (Part A), knowledge regarding infection control (Part B), practices regarding infection control (Part C), and additional relevant information (Part D). Descriptive and inferential statistics, with the help of a statistician, were used to analyse the data. The results of the study revealed that radiographers had average knowledge and practice in terms of infection control. The results revealed a significant association between age and knowledge (P<0.05). In phase two, a draft guideline was developed. The guideline’s content is based on 20 gaps identified in phase one of the study, as well as literature. The draft guideline consists of seven sets of recommendations: hand hygiene, personal hygiene, personal protective equipment (PPE), safe handling of sharps and sharp containers, decontamination and cleaning, housekeeping, and routine infection control practices. Reliability and validity were ensured. Ethical considerations were considered throughout the study. Respect for persons, beneficence and justice were adhered to. The study is the first in the field of radiography in Malawi. Results of this study should contribute to the body of knowledge of radiography practice. The results are to be used to inform practicing radiographers, heads of departments, the Ministry of Health and Population, and other health practitioners about the current practices and knowledge of radiographers in government referral hospitals in Malawi. The draft guideline should facilitate sound knowledge and practices regarding infection control among practicing radiographers in these departments. Recommendations include further development and implementation of the draft guideline, and radiography education and development of further research on infection control in the radiography profession, specifically in the African context.
- Full Text:
- Date Issued: 2017
- Authors: Nyirenda, Denis Charles Glad
- Date: 2017
- Subjects: Radiologic technologists , Radiography, Medical -- Practice Cross infection -- Prevention
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/47848 , vital:40387
- Description: Infection control is an essential cornerstone of clinical care at all healthcare settings. The changing pattern of infections emphasises the need for all healthcare workers, including radiographers, to implement and strictly adhere to standard infection control precautions (SICP) that will protect both patients and healthcare workers from healthcare associated infections (HAIs). However, implementing SICP can be difficult, especially if radiographers do not have adequate knowledge, and skilled practices, in infection control. As a practicing radiographer and a health educator, the researcher observed that there were discrepancies regarding implementation of SICP by radiographers in Malawi. No study has been conducted to explore and describe the knowledge and practices of radiographers regarding infection control in radiology departments in Malawi. There are also no infection control guidelines. These gaps led to this study being conducted. The aim of the study was to explore, and describe, knowledge and practices of radiographers regarding infection control in radiology departments in government referral hospitals in Malawi in order to develop a draft guideline for infection control to facilitate sound knowledge and practices of radiographers regarding infection control in these departments. The study took place in four government referral hospitals and followed a quantitative, exploratory, and descriptive design that was contextual in nature. The study was conducted in two phases. In the first one a self-administered questionnaire was used to explore and describe the knowledge and practices of radiographers regarding infection control in government referral hospitals in Malawi. The second one included the development of a draft guideline for infection control in order to facilitate sound knowledge and practices of radiographers regarding infection control in government referral hospitals in Malawi. In phase one, the research population consisted of 80 permanently employed radiographers. A census sampling method was used to select 62 respondents. The data were collected by means of a self-administered questionnaire that was developed based on a literature review. Some questions were adapted from an existing questionnaire. The questionnaire consisted of questions and statements. It had four parts: demographic information (Part A), knowledge regarding infection control (Part B), practices regarding infection control (Part C), and additional relevant information (Part D). Descriptive and inferential statistics, with the help of a statistician, were used to analyse the data. The results of the study revealed that radiographers had average knowledge and practice in terms of infection control. The results revealed a significant association between age and knowledge (P<0.05). In phase two, a draft guideline was developed. The guideline’s content is based on 20 gaps identified in phase one of the study, as well as literature. The draft guideline consists of seven sets of recommendations: hand hygiene, personal hygiene, personal protective equipment (PPE), safe handling of sharps and sharp containers, decontamination and cleaning, housekeeping, and routine infection control practices. Reliability and validity were ensured. Ethical considerations were considered throughout the study. Respect for persons, beneficence and justice were adhered to. The study is the first in the field of radiography in Malawi. Results of this study should contribute to the body of knowledge of radiography practice. The results are to be used to inform practicing radiographers, heads of departments, the Ministry of Health and Population, and other health practitioners about the current practices and knowledge of radiographers in government referral hospitals in Malawi. The draft guideline should facilitate sound knowledge and practices regarding infection control among practicing radiographers in these departments. Recommendations include further development and implementation of the draft guideline, and radiography education and development of further research on infection control in the radiography profession, specifically in the African context.
- Full Text:
- Date Issued: 2017