- Title
- Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches:
- Creator
- Noundou, Xavier S, Musyoka, Thommas M, Moses, Vuyani, Ndinteh, Derek T, Mnkandhla, Dumisani, Hoppe, Heinrich C, Tastan Bishop, Özlem, Krause, Rui W M
- Date
- 2019
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/162975
- Identifier
- vital:41001
- Identifier
- https://0-doi.org.wam.seals.ac.za/10.1038/s41598-019-41403-x
- Description
- According to the 2018 report of the United Nations Programme on HIV/AIDS (UNAIDS), acquired immune deficiency syndrome (AIDS), a disease caused by the human immunodeficiency virus (HIV), remains a significant public health problem. The non-existence of a cure or effective vaccine for the disease and the associated emergence of resistant viral strains imply an urgent need for the discovery of novel anti-HIV drug candidates. The current study aimed to identify potential anti-retroviral compounds from Alchornea cordifolia.
- Format
- 10 pages, pdf
- Language
- English
- Relation
- Scientific reports, Siwe-Noundou, X., Musyoka, T.M., Moses, V., Ndinteh, D.T., Mnkandhla, D., Hoppe, H., Bishop, Ö.T. and Krause, R.W., 2019. Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches. Scientific reports, 9(1), pp.1-9, Scientific reports volume 9 number 1 1 9 March 2019 2045-2322
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Nature Terms and Conditions Statement (https://www.nature.com/info/terms-and-conditions)
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Tastan Bishop, Ozlem (Prof)
RU Research Unit in Bioinformatics (RUBi)
Hoppe, Heinrich C (Prof)
Krause, Rui Werner Maçedo (Prof)
RU Department of Biochemistry, Microbiology and Biotechnology
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia.pdf | 3 MB | Adobe Acrobat PDF | View Details Download |