Distribution and ecological assessment of heavy metals in irrigation channel sediments in a typical rural area of south China
- Gu, Chiming, Liu, Yi, Li, Zhiguo, Mohamed, Ibrahim, Zhang, Ronghua, Brooks, Margot, Chen, Fang
- Authors: Gu, Chiming , Liu, Yi , Li, Zhiguo , Mohamed, Ibrahim , Zhang, Ronghua , Brooks, Margot , Chen, Fang
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66924 , vital:29000 , ISSN 0925-8574 , https://doi.org/10.1016/j.ecoleng.2016.01.054
- Description: Publisher version , Elevated levels of heavy metals in sediments of irrigation channels can pose risks for crops and livestock, as well as for human health. In this study sediment samples were collected from the irrigation channel in a typical rural area of south China, and digested, in order to analyze their contents for the presence of heavy metals Cu, Zn, Pb, Cr, Cd, and Ni, as well as the non-metal As, to assess total concentrations and pollution levels. The pollution load index and potential ecological risk index of these elements were utilized to assess contamination levels and ecotoxicity. Our results showed that the concentrations of the 7 elements were in the order of Zn > Ni > Cr > Cu > As > Pb > Cd. With the exception of Cr and Pb, concentrations of elements were higher than their background in soil, especially for Cd (1.79 mg kg−1), As (99.61 mg kg−1) and Ni (142.62 mg kg−1), which were 18.49, 8.89 and 5.30 times their background concentrations, respectively. The whole sampled zone was characterized by medium pollution and had a very high potential ecological risk. The area of arable land presented a medium pollution risk, while areas near to the path or road showed high risk of pollution. The predominant contributors to elevated ecological risk for the whole zone were Cd and As.
- Full Text: false
- Authors: Gu, Chiming , Liu, Yi , Li, Zhiguo , Mohamed, Ibrahim , Zhang, Ronghua , Brooks, Margot , Chen, Fang
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66924 , vital:29000 , ISSN 0925-8574 , https://doi.org/10.1016/j.ecoleng.2016.01.054
- Description: Publisher version , Elevated levels of heavy metals in sediments of irrigation channels can pose risks for crops and livestock, as well as for human health. In this study sediment samples were collected from the irrigation channel in a typical rural area of south China, and digested, in order to analyze their contents for the presence of heavy metals Cu, Zn, Pb, Cr, Cd, and Ni, as well as the non-metal As, to assess total concentrations and pollution levels. The pollution load index and potential ecological risk index of these elements were utilized to assess contamination levels and ecotoxicity. Our results showed that the concentrations of the 7 elements were in the order of Zn > Ni > Cr > Cu > As > Pb > Cd. With the exception of Cr and Pb, concentrations of elements were higher than their background in soil, especially for Cd (1.79 mg kg−1), As (99.61 mg kg−1) and Ni (142.62 mg kg−1), which were 18.49, 8.89 and 5.30 times their background concentrations, respectively. The whole sampled zone was characterized by medium pollution and had a very high potential ecological risk. The area of arable land presented a medium pollution risk, while areas near to the path or road showed high risk of pollution. The predominant contributors to elevated ecological risk for the whole zone were Cd and As.
- Full Text: false
Indolyl-3-ethanone-α-thioethers: a promising new class of non-toxic antimalarial agents
- Svogie, Archibald L, Isaacs, Michelle, Hoppe, Heinrich C, Khanye, Setshaba D, Veale, Clinton G L
- Authors: Svogie, Archibald L , Isaacs, Michelle , Hoppe, Heinrich C , Khanye, Setshaba D , Veale, Clinton G L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66233 , vital:28920 , https://doi.org/10.1016/j.ejmech.2016.02.056
- Description: publisher version , The success of chemotherapeutics in easing the burden of malaria is under continuous threat from ever-evolving parasite resistance, including resistance to artemisinin combination therapies. Therefore, the discovery of new classes of antimalarials which inhibit new biological targets is imperative to controlling malaria. Accordingly, we report here the discovery of indolyl-3-ethanone-α-thioethers, a new class of antimalarial compounds with encouraging activity. Synthesis of a focused library of compounds revealed important insight into the SAR of this class of compounds, including critical information regarding the position and chemical nature of substituents on both the thiophenol and indole rings. This investigation ultimately led to the discovery of two hit compounds (16 and 27) which exhibited nano molar in vitro antimalarial activity coupled to no observable toxicity against a HeLa cell line.
- Full Text: false
- Authors: Svogie, Archibald L , Isaacs, Michelle , Hoppe, Heinrich C , Khanye, Setshaba D , Veale, Clinton G L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66233 , vital:28920 , https://doi.org/10.1016/j.ejmech.2016.02.056
- Description: publisher version , The success of chemotherapeutics in easing the burden of malaria is under continuous threat from ever-evolving parasite resistance, including resistance to artemisinin combination therapies. Therefore, the discovery of new classes of antimalarials which inhibit new biological targets is imperative to controlling malaria. Accordingly, we report here the discovery of indolyl-3-ethanone-α-thioethers, a new class of antimalarial compounds with encouraging activity. Synthesis of a focused library of compounds revealed important insight into the SAR of this class of compounds, including critical information regarding the position and chemical nature of substituents on both the thiophenol and indole rings. This investigation ultimately led to the discovery of two hit compounds (16 and 27) which exhibited nano molar in vitro antimalarial activity coupled to no observable toxicity against a HeLa cell line.
- Full Text: false
Remastered:
- Authors: Ntombela, N
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146423 , vital:38524 , https://www.e-flux.com/announcements/49246/the-exhibitionist-journal-on-exhibition-making/
- Description: Exhibition abstract. Issue 12 scrutinizes our founding premise, that The Exhibitionist is a journal “by curators, for curators.” When we launched six years ago, this circuit of self-reflection seemed necessary, and enabled a conversation that was not available in other venues. But one effect of this focus, as we see it now, was a siloing-off of curatorial thinking from other parts of the field of exhibition making—which is, after all, based in collective forms of authorship.
- Full Text:
- Authors: Ntombela, N
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146423 , vital:38524 , https://www.e-flux.com/announcements/49246/the-exhibitionist-journal-on-exhibition-making/
- Description: Exhibition abstract. Issue 12 scrutinizes our founding premise, that The Exhibitionist is a journal “by curators, for curators.” When we launched six years ago, this circuit of self-reflection seemed necessary, and enabled a conversation that was not available in other venues. But one effect of this focus, as we see it now, was a siloing-off of curatorial thinking from other parts of the field of exhibition making—which is, after all, based in collective forms of authorship.
- Full Text:
Responding to poverty in the light of the post-development debate: Some insights from the NGO Enda Graf Sahel
- Authors: Matthews, Sally
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142487 , vital:38084 , https://www.ajol.info/index.php/ad/article/view/135799
- Description: How can we take on board the many valuable insights of post-development theory without seeming to advocate indifference and inaction in the face of the misery that many people in the world experience daily? In this paper, I provide a partial response to this question. I begin by looking at some of the alternative strategies offered in post-development literature and set out to show that while there are several problems with these alternatives, to read post-development theory as advocating indifference or inaction is to read it uncharitably. Secondly, I draw on the experiences of the non-governmental organisation (NGO) Enda Graf Sahel in Dakar, Senegal to suggest some ways in which the insights of post-development theory, or some versions of post-development theory, can be taken into consideration without leading to inaction or indifference in the face of the suffering of those who occupy a less advantaged position in contemporary relations of power and privilege.
- Full Text:
- Authors: Matthews, Sally
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142487 , vital:38084 , https://www.ajol.info/index.php/ad/article/view/135799
- Description: How can we take on board the many valuable insights of post-development theory without seeming to advocate indifference and inaction in the face of the misery that many people in the world experience daily? In this paper, I provide a partial response to this question. I begin by looking at some of the alternative strategies offered in post-development literature and set out to show that while there are several problems with these alternatives, to read post-development theory as advocating indifference or inaction is to read it uncharitably. Secondly, I draw on the experiences of the non-governmental organisation (NGO) Enda Graf Sahel in Dakar, Senegal to suggest some ways in which the insights of post-development theory, or some versions of post-development theory, can be taken into consideration without leading to inaction or indifference in the face of the suffering of those who occupy a less advantaged position in contemporary relations of power and privilege.
- Full Text:
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