A civic engagement:
- Authors: Amner, Roderick J
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159366 , vital:40291 , https://hdl.handle.net/10520/EJC139908
- Description: Rod Amner looks at how a small South African newspaper is managing to punch well above its weight.
- Full Text:
- Authors: Amner, Roderick J
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159366 , vital:40291 , https://hdl.handle.net/10520/EJC139908
- Description: Rod Amner looks at how a small South African newspaper is managing to punch well above its weight.
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Between a rock and a hard place:
- Authors: Keeton, Gavin
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159401 , vital:40294 , https://hdl.handle.net/10520/EJC139947
- Description: Gavin Keeton takes an economist's tour of the current crisis : how did it happen and what does it mean?
- Full Text:
- Authors: Keeton, Gavin
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159401 , vital:40294 , https://hdl.handle.net/10520/EJC139947
- Description: Gavin Keeton takes an economist's tour of the current crisis : how did it happen and what does it mean?
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Cancer stem cells in breast cancer and metastasis:
- Lawson, Jessica C, Blatch, Gregory L, Edkins, Adrienne L
- Authors: Lawson, Jessica C , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165057 , vital:41205 , DOI: 10.1007/s10549-009-0524-9
- Description: The cancer stem cell theory poses that cancers develop from a subset of malignant cells that possess stem cell characteristics and has been proposed to account for the development of a variety of malignancies, including breast cancer. These cancer stem cells (CSC) possess characteristics of both stem cells and cancer cells, in that they have the properties of self-renewal, asymmetric cell division, resistance to apoptosis, independent growth, tumourigenicity and metastatic potential. A CSC origin for breast cancer can neatly explain both the heterogeneity of breast cancers and the relapse of the tumours after treatment. However, many reports on CSC in the breast are contradictory. There is variation with respect to how breast cancer stem cells should be identified, their characteristics and a possible lack of correlation between clinical outcome and breast cancer stem cell status of a tumour. These combined factors have made breast cancer stem cells a highly contentious issue. In this review, we highlight the progress in the analysis of cancer stem cells, with an emphasis on breast cancer.
- Full Text:
- Authors: Lawson, Jessica C , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165057 , vital:41205 , DOI: 10.1007/s10549-009-0524-9
- Description: The cancer stem cell theory poses that cancers develop from a subset of malignant cells that possess stem cell characteristics and has been proposed to account for the development of a variety of malignancies, including breast cancer. These cancer stem cells (CSC) possess characteristics of both stem cells and cancer cells, in that they have the properties of self-renewal, asymmetric cell division, resistance to apoptosis, independent growth, tumourigenicity and metastatic potential. A CSC origin for breast cancer can neatly explain both the heterogeneity of breast cancers and the relapse of the tumours after treatment. However, many reports on CSC in the breast are contradictory. There is variation with respect to how breast cancer stem cells should be identified, their characteristics and a possible lack of correlation between clinical outcome and breast cancer stem cell status of a tumour. These combined factors have made breast cancer stem cells a highly contentious issue. In this review, we highlight the progress in the analysis of cancer stem cells, with an emphasis on breast cancer.
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Cretaceous erosion in central South Africa: evidence from upper-crustal xenoliths in kimberlite diatremes
- Hanson, E Kelsey, Moore, John M, Bordy, Emese M, Marsh, Julian S, Howarth, Geoffrey H, Robey, Julian van Aardt
- Authors: Hanson, E Kelsey , Moore, John M , Bordy, Emese M , Marsh, Julian S , Howarth, Geoffrey H , Robey, Julian van Aardt
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144978 , vital:38397 , https://doi.org/10.2113/gssajg.112.2.125
- Description: Twelve Group II and fourteen Group I kimberlite diatremes in central South Africa were examined for upper crustal xenoliths in order to estimate the extent of various lithological units of the Karoo Supergroup in the main Karoo basin at times of kimberlite eruption, the Cretaceous erosional history of the area, and the approximate vertical extent of the kimberlite diatremes prior to erosion. Sandstone and amygdaloidal basaltic lava xenoliths from the Karoo Supergroup were specifically selected as their modal mineralogies and geochemical compositions respectively can be attributed to specific stratigraphic positions within the Karoo Supergroup. Results indicated that, at the time of Group II kimberlite eruption (120 Ma), basaltic lavas of the Drakensberg Group covered the entire area, but by the time of Group I kimberlite eruption (85 Ma), they were restricted to the south-eastern half of the study area.
- Full Text:
- Authors: Hanson, E Kelsey , Moore, John M , Bordy, Emese M , Marsh, Julian S , Howarth, Geoffrey H , Robey, Julian van Aardt
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144978 , vital:38397 , https://doi.org/10.2113/gssajg.112.2.125
- Description: Twelve Group II and fourteen Group I kimberlite diatremes in central South Africa were examined for upper crustal xenoliths in order to estimate the extent of various lithological units of the Karoo Supergroup in the main Karoo basin at times of kimberlite eruption, the Cretaceous erosional history of the area, and the approximate vertical extent of the kimberlite diatremes prior to erosion. Sandstone and amygdaloidal basaltic lava xenoliths from the Karoo Supergroup were specifically selected as their modal mineralogies and geochemical compositions respectively can be attributed to specific stratigraphic positions within the Karoo Supergroup. Results indicated that, at the time of Group II kimberlite eruption (120 Ma), basaltic lavas of the Drakensberg Group covered the entire area, but by the time of Group I kimberlite eruption (85 Ma), they were restricted to the south-eastern half of the study area.
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Meeting democracy’s challenge developments:
- Authors: Dugmore, Harry
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159389 , vital:40293 , https://hdl.handle.net/10520/EJC139935
- Description: In a context of declining public participation, can mobile phone technology and 'new media' be used to involve more people in local decision-making, asks Harry Dug more in this exploration of the implications of mobile communication on journalism in the developing world.
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- Authors: Dugmore, Harry
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159389 , vital:40293 , https://hdl.handle.net/10520/EJC139935
- Description: In a context of declining public participation, can mobile phone technology and 'new media' be used to involve more people in local decision-making, asks Harry Dug more in this exploration of the implications of mobile communication on journalism in the developing world.
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Mobile monitors: protecting the will of the people
- Authors: Dugmore, Harry
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159377 , vital:40292 , https://hdl.handle.net/10520/EJC139912
- Description: The use of mobile phone technology in recent African elections has empowered citizens, allowing them to put in place the checks and balances needed to make elections freer and fairer in Africa - and elsewhere in the world, writes Harry Dugmore.
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- Authors: Dugmore, Harry
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159377 , vital:40292 , https://hdl.handle.net/10520/EJC139912
- Description: The use of mobile phone technology in recent African elections has empowered citizens, allowing them to put in place the checks and balances needed to make elections freer and fairer in Africa - and elsewhere in the world, writes Harry Dugmore.
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Steps by steps: the making of the Steps for the Future documentary series, likka Vehkalathi and Don Edkins: book review
- Authors: Schoon, Alette
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159348 , vital:40290 , https://hdl.handle.net/10520/EJC139902
- Description: In a frank, offbeat memoir, Finnish filmmaker Iikka Vehkalahti and his South African partner Don Edkins, tell their story of how they developed an infectious concept, charmed big broadcasters - and nearly didn't get the films made. Alette Schoon gets taken along for the ride.
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- Authors: Schoon, Alette
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159348 , vital:40290 , https://hdl.handle.net/10520/EJC139902
- Description: In a frank, offbeat memoir, Finnish filmmaker Iikka Vehkalahti and his South African partner Don Edkins, tell their story of how they developed an infectious concept, charmed big broadcasters - and nearly didn't get the films made. Alette Schoon gets taken along for the ride.
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The both-and edition:
- Authors: Garman, Anthea
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158817 , vital:40231 , https://hdl.handle.net/10520/EJC139955
- Description: I was driving down the N2 from Cape Town towards the airport recently and scanning the turn-offs for Vanguard Drive, when suddenly I noticed among the shacks that line the road some really interesting buildings. These were not the pale pink matchboxes that periodically spring up in rows alongside the derelict housing that millions of South Africans call home. They were multi-levelled, had large windows and looked like an architect might have had something to do with them. I was heartened at the sight of housing – at last – with humanity in mind. But as I reread the 2010 pieces in this edition, I’m reminded by Jane Duncan in particular (“Whose World Cup?” page 23) that prettifying the ghastly spaces in our world cup cities that will be visible to those international tourists is high on the agenda for our government. But then, I reason, at least someone will benefit from living along the noisy and congested airport route!.
- Full Text:
- Authors: Garman, Anthea
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158817 , vital:40231 , https://hdl.handle.net/10520/EJC139955
- Description: I was driving down the N2 from Cape Town towards the airport recently and scanning the turn-offs for Vanguard Drive, when suddenly I noticed among the shacks that line the road some really interesting buildings. These were not the pale pink matchboxes that periodically spring up in rows alongside the derelict housing that millions of South Africans call home. They were multi-levelled, had large windows and looked like an architect might have had something to do with them. I was heartened at the sight of housing – at last – with humanity in mind. But as I reread the 2010 pieces in this edition, I’m reminded by Jane Duncan in particular (“Whose World Cup?” page 23) that prettifying the ghastly spaces in our world cup cities that will be visible to those international tourists is high on the agenda for our government. But then, I reason, at least someone will benefit from living along the noisy and congested airport route!.
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