- Title
- Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study
- Creator
- Nyamai, Dorothy Wavinya, Tastan Bishop, Özlem
- Date
- 2018
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/148368
- Identifier
- vital:38733
- Identifier
- DOI: 10.1101/440891
- Description
- Treatment of parasitic diseases has been challenging due to evolution of drug resistant parasites, and thus there is need to identify new class of drugs and drug targets. Protein translation is important for survival of malarial parasite, Plasmodium, and the pathway is present in all of its life cycle stages. Aminoacyl tRNA synthetases are primary enzymes in protein translation as they catalyse amino acid addition to the cognate tRNA. This study sought to understand differences between Plasmodium and human aminoacyl tRNA synthetases through bioinformatics analysis.
- Format
- Language
- English
- Relation
- Malaria journal, Nyamai, D.W. and Bishop, Ö.T., 2019. Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study. Malaria journal, 18(1), p.34., Malaria journal volume 18 number 1 p.34 2018 1475-2875
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the BioMed Central Limited Terms and Conditions statement (https://www.biomedcentral.com/terms-and-conditions)
- Hits: 556
- Visitors: 668
- Downloads: 120
Thumbnail | File | Description | Size | Format | |||
---|---|---|---|---|---|---|---|
View Details | SOURCE1 | Aminoacyl tRNA synthetases as malarial drug targets.pdf | 4 MB | Adobe Acrobat PDF | View Details |