- Title
- STAT3 interacts directly with Hsp90:
- Creator
- Prinsloo, Earl, Kramer, Adam H, Edkins, Adrienne L, Blatch, Gregory L
- Date
- 2012
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/165142
- Identifier
- vital:41212
- Identifier
- DOI: 10.1002/iub.607
- Description
- Heat shock protein 90 (Hsp90) functionally modulates signal transduction. The signal transducer and activator of transcription 3 (STAT3) mediates interleukin‐6 family cytokine signaling. Aberrant activation and mutation of STAT3 is associated with oncogenesis and immune disorders, respectively. Hsp90 and STAT3 have previously been shown to colocalize and coimmunoprecipitate in common complexes.
- Format
- 8 pages, pdf
- Language
- English
- Relation
- IUBMB life, Prinsloo, E., Kramer, A.H., Edkins, A.L. and Blatch, G.L., 2012. STAT3 interacts directly with Hsp90. IUBMB life, 64(3), pp.266-273, IUBMB life volume 64 number 3 266 273 January 2012 1521-6551
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Wiley Library Online Terms of Use Statement (https://onlinelibrary.wiley.com/terms-and-conditions)
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Prinsloo, Earl (Dr)
Edkins, Adrienne Lesley (Associate Prof)
Blatch, Gregory Lloyd (Prof)
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 09. Industry, Innovation and Infrastructure
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details | SOURCE1 | STAT3 interacts directly with Hsp90.pdf | 657 KB | Adobe Acrobat PDF | View Details |