- Title
- Plaxenone A and B: Cytotoxic halogenated monoterpenes from the South African red seaweed Plocamium maxillosum
- Creator
- Knott, Michael G, de la Mare, Jo-Anne, Edkins, Adrienne L, Zhang, Angel, Stillman, Martin J, Bolton, John J, Antunes, Edith M, Beukes, Denzil R
- Date
- 2019
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/164446
- Identifier
- vital:41119
- Identifier
- https://doi.org/10.1016/j.phytol.2018.12.009
- Description
- The endemic South African red seaweed Plocamium maxillosum (Poiret) Lamouroux produces two unusual isomeric dichlorinated cyclohexenone monoterpenes, plaxenone A and B (1 and 2). The structures of the isolated compounds were determined from spectroscopic data and their absolute configuration was determined by comparison of the experimental and calculated ECD spectra. Compounds 1 and 2 inhibit the growth of MDA-MB-231 breast cancer cells.
- Format
- 4 pages, pdf
- Language
- English
- Relation
- Phytochemistry Letters, Knott, M.G., de la Mare, J.A., Edkins, A.L., Zhang, A., Stillman, M.J., Bolton, J.J., Antunes, E.M. and Beukes, D.R., 2019. Plaxenone A and B: Cytotoxic halogenated monoterpenes from the South African red seaweed Plocamium maxillosum. Phytochemistry Letters, 29, pp.182-185, Phytochemistry Letters volume 29 number 182 185 February 2019 1874-3900
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Plaxenone A and B.pdf | 671 KB | Adobe Acrobat PDF | View Details Download |