A Discussion Of Wireless Security Technologies
- Janse van Rensburg, Johanna, Irwin, Barry V W
- Authors: Janse van Rensburg, Johanna , Irwin, Barry V W
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429852 , vital:72645 , https://www.researchgate.net/profile/Barry-Ir-win/publication/228864029_A_DISCUSSION_OF_WIRELESS_SECURITY_TECHNOLOGIES/links/53e9c5190cf28f342f41492b/A-DISCUSSION-OF-WIRELESS-SECURITY-TECHNOLOGIES.pdf
- Description: The 802.11 standard contains a number of problems, ranging from in-terference, co-existence issues, exposed terminal problems and regula-tions to security. Despite all of these it has become a widely deployed technology as an extension of companies’ networks to provide mobility. In this paper the focus will be on the security issues of 802.11. Several solutions for the deployment of 802.11 security exists today, ranging from WEP, WPA, VPN and 802.11 i, each providing a different level of security. These technologies contain pros and cons which need to be understood in order to implement an appropriate solution suited to a specific scenario.
- Full Text:
- Authors: Janse van Rensburg, Johanna , Irwin, Barry V W
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429852 , vital:72645 , https://www.researchgate.net/profile/Barry-Ir-win/publication/228864029_A_DISCUSSION_OF_WIRELESS_SECURITY_TECHNOLOGIES/links/53e9c5190cf28f342f41492b/A-DISCUSSION-OF-WIRELESS-SECURITY-TECHNOLOGIES.pdf
- Description: The 802.11 standard contains a number of problems, ranging from in-terference, co-existence issues, exposed terminal problems and regula-tions to security. Despite all of these it has become a widely deployed technology as an extension of companies’ networks to provide mobility. In this paper the focus will be on the security issues of 802.11. Several solutions for the deployment of 802.11 security exists today, ranging from WEP, WPA, VPN and 802.11 i, each providing a different level of security. These technologies contain pros and cons which need to be understood in order to implement an appropriate solution suited to a specific scenario.
- Full Text:
A new and earlier record of Chrysomya megacephala in South Africa, with notes on another exotic species, Calliphora vicina (Diptera Calliphoridae)
- Williams, Kirstin A, Villet, Martin H
- Authors: Williams, Kirstin A , Villet, Martin H
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/440710 , vital:73805 , https://hdl.handle.net/10520/EJC84554
- Description: South African records of Chrysomya megacephala and Calliphora vicina are reviewed and plotted on maps. Dispersal routes of these two forensically and medically important blowfly species are discussed. Emphasised is the importance of deposition of voucher material in museum collections.
- Full Text:
- Authors: Williams, Kirstin A , Villet, Martin H
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/440710 , vital:73805 , https://hdl.handle.net/10520/EJC84554
- Description: South African records of Chrysomya megacephala and Calliphora vicina are reviewed and plotted on maps. Dispersal routes of these two forensically and medically important blowfly species are discussed. Emphasised is the importance of deposition of voucher material in museum collections.
- Full Text:
A stability-indicating high performance liquid chromatographic assay for the determination of orlistat in capsules
- Mohammadi, Ali, Haririan, I, Rezanour, Nasrin, Ghiasi, L, Walker, Roderick B
- Authors: Mohammadi, Ali , Haririan, I , Rezanour, Nasrin , Ghiasi, L , Walker, Roderick B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184267 , vital:44195 , xlink:href="https://doi.org/10.1016/j.chroma.2006.03.038"
- Description: A stability-indicating HPLC method was developed and validated for the quantitative determination of orlistat in capsule dosage forms. An isocratic separation was achieved using a Perfectsil® target ODS-3, 250 mm × 4.6 mm i.d., 5 μm particle size column with a flow rate of 0.7 ml/min and using a UV detector to monitor the eluate at 210 nm. The mobile phase consisted of methanol:acetonitrile:trifluoroacetic acid (82.5:17.5:0.01, v/v/v). The drug was subjected oxidation, hydrolysis, photolysis and heat to apply stress conditions. Complete separation was achieved for the parent compound and all degradation products in an overall analytical run time of approximately 15 min with the parent compound orlistat eluting at approximately 9 min. The method was linear over the concentration range of 0.02–0.75 mg/ml (r = 0.9998) with a limit of detection and quantitation 0.006 and 0.02 mg/ml, respectively. The method has the requisite accuracy, selectivity, sensitivity and precision to assay orlistat in capsules. Degradation products resulting from the stress studies did not interfere with the detection of orlistat and the assay is thus stability-indicating.
- Full Text:
- Authors: Mohammadi, Ali , Haririan, I , Rezanour, Nasrin , Ghiasi, L , Walker, Roderick B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184267 , vital:44195 , xlink:href="https://doi.org/10.1016/j.chroma.2006.03.038"
- Description: A stability-indicating HPLC method was developed and validated for the quantitative determination of orlistat in capsule dosage forms. An isocratic separation was achieved using a Perfectsil® target ODS-3, 250 mm × 4.6 mm i.d., 5 μm particle size column with a flow rate of 0.7 ml/min and using a UV detector to monitor the eluate at 210 nm. The mobile phase consisted of methanol:acetonitrile:trifluoroacetic acid (82.5:17.5:0.01, v/v/v). The drug was subjected oxidation, hydrolysis, photolysis and heat to apply stress conditions. Complete separation was achieved for the parent compound and all degradation products in an overall analytical run time of approximately 15 min with the parent compound orlistat eluting at approximately 9 min. The method was linear over the concentration range of 0.02–0.75 mg/ml (r = 0.9998) with a limit of detection and quantitation 0.006 and 0.02 mg/ml, respectively. The method has the requisite accuracy, selectivity, sensitivity and precision to assay orlistat in capsules. Degradation products resulting from the stress studies did not interfere with the detection of orlistat and the assay is thus stability-indicating.
- Full Text:
Accuracy of the activation energy calculated from a thermoluminescence glow‐peak using a method that uses three points on the peak
- Ogundare, F O, Chithambo, Makaiko L
- Authors: Ogundare, F O , Chithambo, Makaiko L
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123016 , vital:35397 , https://doi:10.1002/pssc.200521077
- Description: The utility of thermoluminescence (TL) in detecting changes in defect concentration in insulators is well established [1–3]. The underlying premise leading to the emission of TL is that exposure of a material to ionizing radiation causes a redistribution of charge in defect centres within the material. When the material is heated at a controlled linear rate, the thermoluminescence is emitted as a temperature-dependent set of peaks collectively known as a glow-curve. The shape and intensity of each of the glow-peaks may be characterized by a set of parameters consisting of the activation energy E, the frequency factors, the number of electrons n0 trapped in defect centres at the start of the heating, and the order of kinetics b. The order of kinetics b is an indication of the retrapping probability i.e. the probability that a free electron from the conduction band will be retrapped rather than recombine with a hole at a recombination centre to produce thermoluminescence. Retrapping of electrons reduces the TL intensity at any particular temperature during the heating process. The physical mechanisms of TL associated with a given glow curve are unique and may be characterized by analysis of the glow-curve for the said kinetic parameters.
- Full Text:
- Authors: Ogundare, F O , Chithambo, Makaiko L
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123016 , vital:35397 , https://doi:10.1002/pssc.200521077
- Description: The utility of thermoluminescence (TL) in detecting changes in defect concentration in insulators is well established [1–3]. The underlying premise leading to the emission of TL is that exposure of a material to ionizing radiation causes a redistribution of charge in defect centres within the material. When the material is heated at a controlled linear rate, the thermoluminescence is emitted as a temperature-dependent set of peaks collectively known as a glow-curve. The shape and intensity of each of the glow-peaks may be characterized by a set of parameters consisting of the activation energy E, the frequency factors, the number of electrons n0 trapped in defect centres at the start of the heating, and the order of kinetics b. The order of kinetics b is an indication of the retrapping probability i.e. the probability that a free electron from the conduction band will be retrapped rather than recombine with a hole at a recombination centre to produce thermoluminescence. Retrapping of electrons reduces the TL intensity at any particular temperature during the heating process. The physical mechanisms of TL associated with a given glow curve are unique and may be characterized by analysis of the glow-curve for the said kinetic parameters.
- Full Text:
Actor/actant-network theory as emerging methodology for environmental education research in southern Africa
- Authors: Nhamo, Godwell
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373537 , vital:66702 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122722"
- Description: This paper deliberates on actor/actant-network theory (AANT) as methodology for policy research in environmental education (EE). Insights are drawn from work that applied AANT to research environmental policy processes surrounding the formulation and implementation of South Africa’s Plastic Bags Regulations of 2003. The paper reveals that the application of AANT methodology made it possible to trace relationships, actors, actants and actor/actant-networks surrounding the Plastic Bags Regulations as quasi-object (token). The methodology also enabled a focus on understanding and investigating tensions, debates and responses emerging from the policy process. The findings were that after the promulgation of the first draft of the Plastic Bags Regulations in May 2000, tensions emerged around the nature of regulation (whether to use the command and control approach – preferred by Organised Government – or self regulation – preferred by Organised Business and Organised Labour). From these findings, a series of conceptual frameworks were drawn up as identified around key actors and actor/actant-networks. The conceptual frameworks included among them, Organised Government, Organised Business and Organised Labour.
- Full Text:
- Authors: Nhamo, Godwell
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373537 , vital:66702 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122722"
- Description: This paper deliberates on actor/actant-network theory (AANT) as methodology for policy research in environmental education (EE). Insights are drawn from work that applied AANT to research environmental policy processes surrounding the formulation and implementation of South Africa’s Plastic Bags Regulations of 2003. The paper reveals that the application of AANT methodology made it possible to trace relationships, actors, actants and actor/actant-networks surrounding the Plastic Bags Regulations as quasi-object (token). The methodology also enabled a focus on understanding and investigating tensions, debates and responses emerging from the policy process. The findings were that after the promulgation of the first draft of the Plastic Bags Regulations in May 2000, tensions emerged around the nature of regulation (whether to use the command and control approach – preferred by Organised Government – or self regulation – preferred by Organised Business and Organised Labour). From these findings, a series of conceptual frameworks were drawn up as identified around key actors and actor/actant-networks. The conceptual frameworks included among them, Organised Government, Organised Business and Organised Labour.
- Full Text:
Alternative media: a viable option for Southern Africa?
- Authors: Banda, Fackson
- Date: 2006
- Language: English
- Type: text , article
- Identifier: vital:6328 , http://hdl.handle.net/10962/d1008473 , https://core.ac.uk/download/pdf/145046852.pdf
- Description: preprint , The article attempts a historically and culturally based definition of alternative media. It then gives some case studies to illustrate the efficacy of such media forms, apart from highlighting the problems associated with them. It concludes that alternative media emerge to deal with specific ideological projects and, as such, must be viewed as satisfying a specific need at a specific point in time.
- Full Text:
- Authors: Banda, Fackson
- Date: 2006
- Language: English
- Type: text , article
- Identifier: vital:6328 , http://hdl.handle.net/10962/d1008473 , https://core.ac.uk/download/pdf/145046852.pdf
- Description: preprint , The article attempts a historically and culturally based definition of alternative media. It then gives some case studies to illustrate the efficacy of such media forms, apart from highlighting the problems associated with them. It concludes that alternative media emerge to deal with specific ideological projects and, as such, must be viewed as satisfying a specific need at a specific point in time.
- Full Text:
AmaNdebele, Peter Magubane and Sandra Klopper: book review
- Authors: Simbao, Ruth K
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147336 , vital:38627 , https://0-hdl.handle.net.wam.seals.ac.za/10520/EJC31002
- Description: AmaNdebele is a very attractive book with beautifully reproduced colour photographs taken by the renowned photographer Peter Magubane, who secured enormous credibility as a photojournalist during the violent years of apartheid. While some South African readers who browse through the glossy portrayals of ceremonial attire and homestead decorations may recall Magubane's earlier books such as Soweto speaks (1981) and Soweto: The fruit of fear (1986) in which the photographer laid bare the ferocious violence of apartheid rule, many readers will skip over the nuances of both Magubane's disrupted career and the contentious relationship between the Ndebele people and the South African apartheid government.
- Full Text:
- Authors: Simbao, Ruth K
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147336 , vital:38627 , https://0-hdl.handle.net.wam.seals.ac.za/10520/EJC31002
- Description: AmaNdebele is a very attractive book with beautifully reproduced colour photographs taken by the renowned photographer Peter Magubane, who secured enormous credibility as a photojournalist during the violent years of apartheid. While some South African readers who browse through the glossy portrayals of ceremonial attire and homestead decorations may recall Magubane's earlier books such as Soweto speaks (1981) and Soweto: The fruit of fear (1986) in which the photographer laid bare the ferocious violence of apartheid rule, many readers will skip over the nuances of both Magubane's disrupted career and the contentious relationship between the Ndebele people and the South African apartheid government.
- Full Text:
An Exploration of How Natural Resource Management (NRM) Discourse is Integrated into Key Pedagogic Texts
- Authors: Nsubuga, Yvonne
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373552 , vital:66703 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122753"
- Description: Natural resource management (NRM) education has the potential to improve the quality and relevance of rural education in South Africa. For this potential to be realised, the various educational resources that are commonly used by teachers and learners in rural schools need to incorporate natural resource management knowledge. Using Bernstein’s concepts of classification and his theories on recontextualisation, a content analysis study was carried out to compare the level of NRM integration within the Grade 10 Life Sciences syllabus, and a Grade 10 Life Sciences textbook. Results from the analysis of the syllabus showed that overall only 9% of all the knowledge statements analysed had a strong link to NRM and related issues. The highest percentage of such sentences was found in the Core Knowledge section of the syllabus (21%). For the textbook, only 8% of the analysed items had a strong link to NRM and related issues, with the highest percentage of such items occurring in the Suggested Activities section (16%). However, the level of NRM integration in both documents increased considerably when sentences that had only an implicit link to NRM and related issues were included. It was concluded that both documents provide ample opportunities for NRM learning, although the extent to which this occurs varies among their different sections. The recontextualising role of the Grade 10 Life Sciences textbook was reflected in its relatively higher level of NRM integration in the Suggested Activities category, and in the Glossary category. This study highlights the need for further strengthening of the position of NRM within the Grade 10 Life Sciences syllabus, and for more Bernstein-based research to inform South Africa’s curriculum reform initiatives in environmental education.
- Full Text:
- Authors: Nsubuga, Yvonne
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373552 , vital:66703 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122753"
- Description: Natural resource management (NRM) education has the potential to improve the quality and relevance of rural education in South Africa. For this potential to be realised, the various educational resources that are commonly used by teachers and learners in rural schools need to incorporate natural resource management knowledge. Using Bernstein’s concepts of classification and his theories on recontextualisation, a content analysis study was carried out to compare the level of NRM integration within the Grade 10 Life Sciences syllabus, and a Grade 10 Life Sciences textbook. Results from the analysis of the syllabus showed that overall only 9% of all the knowledge statements analysed had a strong link to NRM and related issues. The highest percentage of such sentences was found in the Core Knowledge section of the syllabus (21%). For the textbook, only 8% of the analysed items had a strong link to NRM and related issues, with the highest percentage of such items occurring in the Suggested Activities section (16%). However, the level of NRM integration in both documents increased considerably when sentences that had only an implicit link to NRM and related issues were included. It was concluded that both documents provide ample opportunities for NRM learning, although the extent to which this occurs varies among their different sections. The recontextualising role of the Grade 10 Life Sciences textbook was reflected in its relatively higher level of NRM integration in the Suggested Activities category, and in the Glossary category. This study highlights the need for further strengthening of the position of NRM within the Grade 10 Life Sciences syllabus, and for more Bernstein-based research to inform South Africa’s curriculum reform initiatives in environmental education.
- Full Text:
Benthic mapping using local aerial photo interpretation and resident taxa inventories for designing marine protected areas
- Shankar, Aswani, Lauer, Matthew
- Authors: Shankar, Aswani , Lauer, Matthew
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/439059 , vital:73541 , xlink:href="https://doi.org/10.1017/S0376892906003183"
- Description: Given the frequent socioeconomic, political and concomitant ecological failures of science-driven marine protected area (MPA) programmes, it is now important to design MPAs by integrating natural and social science research more comprehensively. This study shows how indigenous peoples assisted in the design of MPAs by identifying marine substrates and related resident taxa on aerial photos, information which was then incorporated into a geographical information system (GIS) database, along with dive survey data. Two questions were asked: (1) Is indigenous ecological knowledge accurate enough for mapping the benthos and associated taxa? (2) Is such an approach an appropriate way for assisting in the biological and social design of MPAs in Oceania? Conventional quadrat field dive surveys were used to measure the accuracy of substrate identification by local informants and a visual survey was used to test hypotheses formulated from local knowledge regarding the spatial distribution and relative abundance of non-cryptic species within certain benthic habitats. Equivalence rates between indigenous aerial photo interpretations of dominant benthic substrates and in situ dive surveys were 75–85% for a moderately detailed classification scheme of the benthos, which included nine locally-defined abiotic and biotic benthic classes for the MPA seabed. Similarly, the taxa inventory showed a strong correspondence between the qualitative predictions of local fisherfolk and the quantitative analysis of non-cryptic species distribution, including their relative abundance and geophysical locations. Indigenous people's predictions about the presence or absence of fish in different benthic habitats corresponded 77% and 92% of the time (depending on scoring schema) with in situ visual measurements. These results demonstrate how incorporating local knowledge of benthic heterogeneity, existing biological communities, and particular spatio-temporal events of biological significance into a GIS database can corroborate the production of scientifically reliable base resource maps for designing MPAs in an environmentally and culturally sound fashion. This participatory approach was used to design and then establish MPAs in the Roviana and Vonavona region of the Western Solomon Islands. Under appropriate conditions, interdisciplinary work can complement the design of scientific fishery management and biodiversity conservation prescriptions for coastal Oceania.
- Full Text:
- Authors: Shankar, Aswani , Lauer, Matthew
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/439059 , vital:73541 , xlink:href="https://doi.org/10.1017/S0376892906003183"
- Description: Given the frequent socioeconomic, political and concomitant ecological failures of science-driven marine protected area (MPA) programmes, it is now important to design MPAs by integrating natural and social science research more comprehensively. This study shows how indigenous peoples assisted in the design of MPAs by identifying marine substrates and related resident taxa on aerial photos, information which was then incorporated into a geographical information system (GIS) database, along with dive survey data. Two questions were asked: (1) Is indigenous ecological knowledge accurate enough for mapping the benthos and associated taxa? (2) Is such an approach an appropriate way for assisting in the biological and social design of MPAs in Oceania? Conventional quadrat field dive surveys were used to measure the accuracy of substrate identification by local informants and a visual survey was used to test hypotheses formulated from local knowledge regarding the spatial distribution and relative abundance of non-cryptic species within certain benthic habitats. Equivalence rates between indigenous aerial photo interpretations of dominant benthic substrates and in situ dive surveys were 75–85% for a moderately detailed classification scheme of the benthos, which included nine locally-defined abiotic and biotic benthic classes for the MPA seabed. Similarly, the taxa inventory showed a strong correspondence between the qualitative predictions of local fisherfolk and the quantitative analysis of non-cryptic species distribution, including their relative abundance and geophysical locations. Indigenous people's predictions about the presence or absence of fish in different benthic habitats corresponded 77% and 92% of the time (depending on scoring schema) with in situ visual measurements. These results demonstrate how incorporating local knowledge of benthic heterogeneity, existing biological communities, and particular spatio-temporal events of biological significance into a GIS database can corroborate the production of scientifically reliable base resource maps for designing MPAs in an environmentally and culturally sound fashion. This participatory approach was used to design and then establish MPAs in the Roviana and Vonavona region of the Western Solomon Islands. Under appropriate conditions, interdisciplinary work can complement the design of scientific fishery management and biodiversity conservation prescriptions for coastal Oceania.
- Full Text:
Bioequivalence assessment of generic products an innovative South African approach
- Walker, Roderick B, Kanfer, Isadore, Skinner, Michael F
- Authors: Walker, Roderick B , Kanfer, Isadore , Skinner, Michael F
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184256 , vital:44194 , xlink:href="https://doi.org/10.1080/10601330500534014"
- Description: Concurrent with the implementation of new legislation mandating Generic Substitution in South Africa, a new set of guidelines for bioavailability and bioequivalence have been published. Since one of the main objectives of the new legislation in South Africa relating to Generic Substitution is to ensure that medicines of high quality, safety, and efficacy are made more accessible and more affordable to the wider public, the need to speed up approval of such multi-source products has become a regulatory priority. In order to facilitate this process, various bioequivalence issues have been addressed including important issues such as the acceptance criteria and associated bioequivalence intervals, use of a foreign reference product and the issue of assessing highly variable drugs (HVDs). In addition, dispensations have been made with respect to food effect assessment and variability relating to genetic polymorphism in drug metabolism (genotyping/phenotyping). Furthermore, the use of “old” biostudies submitted in support of an application is subject to expiry date. Acceptance of appropriate data requires that specific criteria such as Cmax and AUC, in addition to the usual considerations, also meet the limits specified by the particular registration authority of the country where such products are intended to be marketed. Generally, these limits require that the 90% confidence interval (CI) for AUC and Cmax test/reference ratios lies within the acceptance interval of 0.80–1.25 calculated using log-transformed data. While such acceptance criteria are, in general, ubiquitous, some differences in acceptance criteria do exist between various countries. The new guidelines for bioavailability/bioequivalence studies developed by the South African regulatory authority, the Medicines Control Council (MCC), makes provision for highly variable drugs and the use of a non-South African reference product. The MCC requires that the acceptance criterion for Cmax ratios be set at 0.75–1.33 while maintaining AUC ratios at 0.80–1.25 using a 90% CI. Furthermore, provision is made to apply scaling based on average bioequivalence assessment and, as an interim measure, consideration has also been given to the use of a foreign reference product provided that equivalence between that product and the innovator product currently available on the South African market can be shown using in vitro testing.
- Full Text:
- Authors: Walker, Roderick B , Kanfer, Isadore , Skinner, Michael F
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184256 , vital:44194 , xlink:href="https://doi.org/10.1080/10601330500534014"
- Description: Concurrent with the implementation of new legislation mandating Generic Substitution in South Africa, a new set of guidelines for bioavailability and bioequivalence have been published. Since one of the main objectives of the new legislation in South Africa relating to Generic Substitution is to ensure that medicines of high quality, safety, and efficacy are made more accessible and more affordable to the wider public, the need to speed up approval of such multi-source products has become a regulatory priority. In order to facilitate this process, various bioequivalence issues have been addressed including important issues such as the acceptance criteria and associated bioequivalence intervals, use of a foreign reference product and the issue of assessing highly variable drugs (HVDs). In addition, dispensations have been made with respect to food effect assessment and variability relating to genetic polymorphism in drug metabolism (genotyping/phenotyping). Furthermore, the use of “old” biostudies submitted in support of an application is subject to expiry date. Acceptance of appropriate data requires that specific criteria such as Cmax and AUC, in addition to the usual considerations, also meet the limits specified by the particular registration authority of the country where such products are intended to be marketed. Generally, these limits require that the 90% confidence interval (CI) for AUC and Cmax test/reference ratios lies within the acceptance interval of 0.80–1.25 calculated using log-transformed data. While such acceptance criteria are, in general, ubiquitous, some differences in acceptance criteria do exist between various countries. The new guidelines for bioavailability/bioequivalence studies developed by the South African regulatory authority, the Medicines Control Council (MCC), makes provision for highly variable drugs and the use of a non-South African reference product. The MCC requires that the acceptance criterion for Cmax ratios be set at 0.75–1.33 while maintaining AUC ratios at 0.80–1.25 using a 90% CI. Furthermore, provision is made to apply scaling based on average bioequivalence assessment and, as an interim measure, consideration has also been given to the use of a foreign reference product provided that equivalence between that product and the innovator product currently available on the South African market can be shown using in vitro testing.
- Full Text:
Cognitive pharmaceutical services and the community pharmacist: are South African patients receiving them and are they willing to pay?
- Hill, Peter W, Dowse, Roslind
- Authors: Hill, Peter W , Dowse, Roslind
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156829 , vital:40054 , DOI 10.1211/ijpp.15.2.0007
- Description: The objectives of this study were to ascertain the opinions of randomly selected South African medical aid members regarding the provision by community pharmacists of patient counselling and information; member satisfaction with pharmacist services; their rating of pharmacist accessibility; and if pharmacists should be reimbursed for providing cognitive pharmaceutical services. Setting A South African private healthcare insurance company.
- Full Text:
- Authors: Hill, Peter W , Dowse, Roslind
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156829 , vital:40054 , DOI 10.1211/ijpp.15.2.0007
- Description: The objectives of this study were to ascertain the opinions of randomly selected South African medical aid members regarding the provision by community pharmacists of patient counselling and information; member satisfaction with pharmacist services; their rating of pharmacist accessibility; and if pharmacists should be reimbursed for providing cognitive pharmaceutical services. Setting A South African private healthcare insurance company.
- Full Text:
Commentary: Negotiating distant influences: globalization and broadcasting policy reforms in Zambia and South Africa
- Authors: Banda, Fackson
- Date: 2006
- Language: English
- Type: text , article
- Identifier: vital:6325 , http://hdl.handle.net/10962/d1008299 , https://doi.org/10.22230/cjc.2006v31n2a1785
- Description: preprint , This commentary looks at the influences of globalisation on broadcasting policy reforms in Zambia and South Africa, with specific focus on such processes as deregulation, privatisation, commercialisation, communitarianism and technological convergence. It concludes that globalisation does not affect southern African countries uniformly; rather, it is refracted in accordance with the different cultural and political experiences of such countries.
- Full Text:
- Authors: Banda, Fackson
- Date: 2006
- Language: English
- Type: text , article
- Identifier: vital:6325 , http://hdl.handle.net/10962/d1008299 , https://doi.org/10.22230/cjc.2006v31n2a1785
- Description: preprint , This commentary looks at the influences of globalisation on broadcasting policy reforms in Zambia and South Africa, with specific focus on such processes as deregulation, privatisation, commercialisation, communitarianism and technological convergence. It concludes that globalisation does not affect southern African countries uniformly; rather, it is refracted in accordance with the different cultural and political experiences of such countries.
- Full Text:
Comparative efficiency of immobilized non-transition metal phthalocyanine photosensitizers for the visible light transformation of chlorophenols
- Agboola, Bolade, Ozoemena, Kenneth I, Nyokong, Tebello
- Authors: Agboola, Bolade , Ozoemena, Kenneth I , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/286043 , vital:56233 , xlink:href="https://doi.org/10.1016/j.molcata.2005.12.009"
- Description: Photolysis of aqueous solutions of chlorophenols (4-chlorophenol, 2,4-dichlorophenol, 2,4,5-trichlorophenol and pentachlorophenol) in the presence of immobilized non-transition metal phthalocyanine photosensitizers onto Amberlite® is presented. The photosensitizers studied are: Al (AlOCPc) and Zn (ZnOCPc) octacarboxyphthalocyanines; Al (AlPcS4) and Zn (ZnPcS4) tetrasulfophthalocyanines; sulfonated phthalocyanine complexes (containing mixtures of differently substituted derivatives) of Al (AlPcSmix), Zn (ZnPcSmix), Ge (GePcSmix), Si (SiPcSmix) and Sn (SnPcSmix). Photolysis of the chlorophenols resulted mainly in the formation of chlorobenzoquinone derivatives. The complexes showed order of activity towards the transformation of pentachlorophenol as follows: ZnOCPc > SiPcSmix > SnPcSmix > ZnPcSmix > GePcSmix > ZnPcS4 > AlPcSmix > AlOCPc > AlPcS4. The generation of singlet oxygen (1O2) by these immobilized MPc photosensitizers was found to play a major role in their photoactivities towards the transformation of these chlorophenols. Langmuir–Hinshelwood (L–H) kinetic model studies showed that the ZnOCPc, GePcSmix and ZnPcSmix photocatalysis occurred on the catalysts surface. © 2005 Elsevier B.V. All rights reserved.
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- Authors: Agboola, Bolade , Ozoemena, Kenneth I , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/286043 , vital:56233 , xlink:href="https://doi.org/10.1016/j.molcata.2005.12.009"
- Description: Photolysis of aqueous solutions of chlorophenols (4-chlorophenol, 2,4-dichlorophenol, 2,4,5-trichlorophenol and pentachlorophenol) in the presence of immobilized non-transition metal phthalocyanine photosensitizers onto Amberlite® is presented. The photosensitizers studied are: Al (AlOCPc) and Zn (ZnOCPc) octacarboxyphthalocyanines; Al (AlPcS4) and Zn (ZnPcS4) tetrasulfophthalocyanines; sulfonated phthalocyanine complexes (containing mixtures of differently substituted derivatives) of Al (AlPcSmix), Zn (ZnPcSmix), Ge (GePcSmix), Si (SiPcSmix) and Sn (SnPcSmix). Photolysis of the chlorophenols resulted mainly in the formation of chlorobenzoquinone derivatives. The complexes showed order of activity towards the transformation of pentachlorophenol as follows: ZnOCPc > SiPcSmix > SnPcSmix > ZnPcSmix > GePcSmix > ZnPcS4 > AlPcSmix > AlOCPc > AlPcS4. The generation of singlet oxygen (1O2) by these immobilized MPc photosensitizers was found to play a major role in their photoactivities towards the transformation of these chlorophenols. Langmuir–Hinshelwood (L–H) kinetic model studies showed that the ZnOCPc, GePcSmix and ZnPcSmix photocatalysis occurred on the catalysts surface. © 2005 Elsevier B.V. All rights reserved.
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Comparative electrochemistry and electrocatalytic activities of cobalt, iron and manganese phthalocyanine complexes axially co-ordinated to mercaptopyridine self-assembled monolayer at gold electrodes
- Ozoemena, Kenneth I, Nyokong, Tebello
- Authors: Ozoemena, Kenneth I , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/286054 , vital:56234 , xlink:href="https://doi.org/10.1016/j.electacta.2005.08.007"
- Description: Comparative surface electrochemistry and electrocatalytic properties of solid ultrathin monolayer films of metallophthalocyanine (MPc) complexes of cobalt (CoPc), iron (FePc) and manganese (MnPc) self-immobilised, via axial ligation reaction, onto preformed 4-mercaptopyridine self-assembled monolayers (SAMs) on gold electrodes have been described. Surface electrochemical parameters of the modified electrodes showed that these MPc-SAMs are densely packed with flat orientations. The electrochemical, electrocatalytic and stability properties of these MPc complexes follow this order: FePc > MnPc > CoPc. This finding is remarkable as it suggests that the success of using this method of self-assembling of MPc onto gold electrode is largely dependent on the bond distance between the pyridine linker and the central metal of the MPc; the shorter the distance, the faster the co-ordination and the better the electrocatalytic properties towards L-cysteine and thiocyanate. Thus, the superiority of FePc-based SAM over those of the MnPc and CoPc, has been proposed to be the result of the more favorable axial co-ordination properties of FePc with pyridine (i.e. shorter Fe–N(pyridine) bond length.
- Full Text:
- Authors: Ozoemena, Kenneth I , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/286054 , vital:56234 , xlink:href="https://doi.org/10.1016/j.electacta.2005.08.007"
- Description: Comparative surface electrochemistry and electrocatalytic properties of solid ultrathin monolayer films of metallophthalocyanine (MPc) complexes of cobalt (CoPc), iron (FePc) and manganese (MnPc) self-immobilised, via axial ligation reaction, onto preformed 4-mercaptopyridine self-assembled monolayers (SAMs) on gold electrodes have been described. Surface electrochemical parameters of the modified electrodes showed that these MPc-SAMs are densely packed with flat orientations. The electrochemical, electrocatalytic and stability properties of these MPc complexes follow this order: FePc > MnPc > CoPc. This finding is remarkable as it suggests that the success of using this method of self-assembling of MPc onto gold electrode is largely dependent on the bond distance between the pyridine linker and the central metal of the MPc; the shorter the distance, the faster the co-ordination and the better the electrocatalytic properties towards L-cysteine and thiocyanate. Thus, the superiority of FePc-based SAM over those of the MnPc and CoPc, has been proposed to be the result of the more favorable axial co-ordination properties of FePc with pyridine (i.e. shorter Fe–N(pyridine) bond length.
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Comprehension and acceptability of a patient information leaflet (PIL) for antiretroviral therapy:
- Mwingira, Betty, Dowse, Roslind
- Authors: Mwingira, Betty , Dowse, Roslind
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156902 , vital:40065 , https://doi.org/10.4102/hsag.v11i3.236
- Description: The patient information leaflet (PIL) is recognised as playing a key role in informing patients about their medicines. The objectives of this research were to evaluate the readability and understanding of a PIL for the first-line ARV (antiretroviral) regimen available in the South African public health sector, and investigate its acceptability in the target Xhosa population. The study took place between August 2003 and July 2004. A PIL was designed for the antiretroviral regimen of stavudine, lamivudine and efavirenz, using established usability guidelines. South African legal requirements concerning PILs were incorporated and the PILs were available in both English and isiXhosa.
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- Authors: Mwingira, Betty , Dowse, Roslind
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/156902 , vital:40065 , https://doi.org/10.4102/hsag.v11i3.236
- Description: The patient information leaflet (PIL) is recognised as playing a key role in informing patients about their medicines. The objectives of this research were to evaluate the readability and understanding of a PIL for the first-line ARV (antiretroviral) regimen available in the South African public health sector, and investigate its acceptability in the target Xhosa population. The study took place between August 2003 and July 2004. A PIL was designed for the antiretroviral regimen of stavudine, lamivudine and efavirenz, using established usability guidelines. South African legal requirements concerning PILs were incorporated and the PILs were available in both English and isiXhosa.
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Confession and public life in post‐apartheid South Africa: A Foucauldian reading of Antjie Krog's country of my skull
- Authors: Garman, Anthea
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159724 , vital:40337 , DOI: 10.1080/02564710608530406
- Description: Truth commissions around the world have given the technique of confession a new public currency and political power. Many works of literature thematising these commissions have also adopted the technique of confession for literary purposes. In this paper I bring Foucault's understanding of the technique of confession, and his discourse on the role of public intellectuals in modernity, to bear upon an examination of Antjie Krog's literary reflection of the work of the Truth and Reconciliation Commission (TRC), entitled Country of My Skull (1998). I look at how this text, and Krog's subsequent public intellectual status as a witness of the TRC, perpetuate the technique of confession without problematising it in ways that Foucault's work would suggest is necessary.
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- Authors: Garman, Anthea
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/159724 , vital:40337 , DOI: 10.1080/02564710608530406
- Description: Truth commissions around the world have given the technique of confession a new public currency and political power. Many works of literature thematising these commissions have also adopted the technique of confession for literary purposes. In this paper I bring Foucault's understanding of the technique of confession, and his discourse on the role of public intellectuals in modernity, to bear upon an examination of Antjie Krog's literary reflection of the work of the Truth and Reconciliation Commission (TRC), entitled Country of My Skull (1998). I look at how this text, and Krog's subsequent public intellectual status as a witness of the TRC, perpetuate the technique of confession without problematising it in ways that Foucault's work would suggest is necessary.
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Creating a low cost VoiceXML Gateway to replace IVR systems for rapid deployment of voice applications
- King, Adam, Terzoli, Alfredo, Clayton, Peter, G
- Authors: King, Adam , Terzoli, Alfredo , Clayton, Peter, G
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/427576 , vital:72448 , https://citeseerx.ist.psu.edu/document?repid=rep1andtype=pdfanddoi=af502fadc7349b9153c37f252bafbe07e86cbfd8
- Description: VoiceXML gateway which can be used to replace traditional Interactive Voice Re-sponse (IVR) platforms. The gateway is created by integrating a VoiceXML inter-preter, OpenVXI and a PBX, Asterisk, producing a Linux based, open source, sys-tem which is both a PBX and a VoiceXML browser. Reasons for choosing the components for the gateway and then the integration of these components are dis-cussed. VoiceXML applications can be used to replace IVR systems, which are then rendered by the gateway.
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- Authors: King, Adam , Terzoli, Alfredo , Clayton, Peter, G
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/427576 , vital:72448 , https://citeseerx.ist.psu.edu/document?repid=rep1andtype=pdfanddoi=af502fadc7349b9153c37f252bafbe07e86cbfd8
- Description: VoiceXML gateway which can be used to replace traditional Interactive Voice Re-sponse (IVR) platforms. The gateway is created by integrating a VoiceXML inter-preter, OpenVXI and a PBX, Asterisk, producing a Linux based, open source, sys-tem which is both a PBX and a VoiceXML browser. Reasons for choosing the components for the gateway and then the integration of these components are dis-cussed. VoiceXML applications can be used to replace IVR systems, which are then rendered by the gateway.
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Cultural significance of biodiversity: the role of medicinal plants in urban African cultural practices in the Eastern Cape, South Africa
- Cocks, Michelle L, Dold, Anthony P
- Authors: Cocks, Michelle L , Dold, Anthony P
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141338 , vital:37963 , DOI: 10.2993/0278-0771(2006)26[60:CSOBTR]2.0.CO;2
- Description: Since the International Convention on Biodiversity in 1992 conservation biologists, ecologists and conservationists have devoted considerable attention to the conservation of biodiversity. With this has come the realization that solutions to biological problems often lie in the mechanisms of social, cultural, and economic systems. This shift has emphasized the relationship between biodiversity and human diversity, or what the Declaration of Belem (1988) calls an “inextricable link” between biological and cultural diversity. The term biocultural diversity was introduced by Posey to describe the concept denoting this link. To date this concept has been used only in reference to “indigenous people” who, as part of their traditional lifestyles, use biodiversity to sustain their cultural identity. Our research, however, demonstrates that Xhosa people (amaXhosa) living in an urban context in the Eastern Cape Province of South Africa continue to use wild plants for cultural purposes and often access these through commercial trade. We suggest that recognition of the cultural and spiritual values associated with wild plants would greatly enhance biodiversity conservation efforts. Recognition of the significant role that wild plants play in fulfilling cultural needs for urban Xhosa people would go a long way towards achieving this.
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- Authors: Cocks, Michelle L , Dold, Anthony P
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141338 , vital:37963 , DOI: 10.2993/0278-0771(2006)26[60:CSOBTR]2.0.CO;2
- Description: Since the International Convention on Biodiversity in 1992 conservation biologists, ecologists and conservationists have devoted considerable attention to the conservation of biodiversity. With this has come the realization that solutions to biological problems often lie in the mechanisms of social, cultural, and economic systems. This shift has emphasized the relationship between biodiversity and human diversity, or what the Declaration of Belem (1988) calls an “inextricable link” between biological and cultural diversity. The term biocultural diversity was introduced by Posey to describe the concept denoting this link. To date this concept has been used only in reference to “indigenous people” who, as part of their traditional lifestyles, use biodiversity to sustain their cultural identity. Our research, however, demonstrates that Xhosa people (amaXhosa) living in an urban context in the Eastern Cape Province of South Africa continue to use wild plants for cultural purposes and often access these through commercial trade. We suggest that recognition of the cultural and spiritual values associated with wild plants would greatly enhance biodiversity conservation efforts. Recognition of the significant role that wild plants play in fulfilling cultural needs for urban Xhosa people would go a long way towards achieving this.
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Design considerations for a reliable and secure wireless network
- Janse van Rensburg, Johanna, Irwin, Barry V W, Zhao, X G
- Authors: Janse van Rensburg, Johanna , Irwin, Barry V W , Zhao, X G
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428199 , vital:72493 , https://www.researchgate.net/profile/Barry-Ir-win/publication/327622818_Design_considerations_for_a_reliable_and_secure_wireless_network/links/5b9a114792851c4ba81819fe/Design-considerations-for-a-reliable-and-secure-wireless-network.pdf
- Description: Wireless Networks have become widely accepted in enterprise net-works and can no longer be considered an experimental technology. However users often experience performance problems due to poor designs. These problems can be attributed to the physical nature of wireless networks, the electromagnetic wave. As a wave propagates through the air it is susceptible to interference, reflection or refraction, to name a few, that changes the wave and ultimately the received signal. However the effect of these can be mitigated with the proper design of a wireless network. In this paper these design consideration will be in-troduced through discussion of visualization packages that aid in the design process. Furthermore we will take a look at the security consid-erations of wireless networks; as, surprisingly even with the ratification of 802.11 i for almost two years now; security is still considered one of the biggest challenges against implementing a wireless local area net-work.
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- Authors: Janse van Rensburg, Johanna , Irwin, Barry V W , Zhao, X G
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428199 , vital:72493 , https://www.researchgate.net/profile/Barry-Ir-win/publication/327622818_Design_considerations_for_a_reliable_and_secure_wireless_network/links/5b9a114792851c4ba81819fe/Design-considerations-for-a-reliable-and-secure-wireless-network.pdf
- Description: Wireless Networks have become widely accepted in enterprise net-works and can no longer be considered an experimental technology. However users often experience performance problems due to poor designs. These problems can be attributed to the physical nature of wireless networks, the electromagnetic wave. As a wave propagates through the air it is susceptible to interference, reflection or refraction, to name a few, that changes the wave and ultimately the received signal. However the effect of these can be mitigated with the proper design of a wireless network. In this paper these design consideration will be in-troduced through discussion of visualization packages that aid in the design process. Furthermore we will take a look at the security consid-erations of wireless networks; as, surprisingly even with the ratification of 802.11 i for almost two years now; security is still considered one of the biggest challenges against implementing a wireless local area net-work.
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Destined to come to blows?: race and constructions of “rational-intellectual” masculinity ten years after apartheid
- Authors: Vincent, Louise
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141619 , vital:37990 , DOI: 10.1177/1097184X05277694
- Description: In 1994, a democratic government came to power in South Africa for the first time in the country's history. But political transition is never a single event or moment. Rather, it is a continuous process that faces setbacks and contradictions. One of the questions we might ask about a society in transition is to what extent its gender order has changed or is changing. The present paper sets out to read the country's transformation drama through the lens of contested conceptions of South African masculinity. The article is focused on one particular version of masculinity which it terms “rational-intellectual man,” and the argument is that a legacy of racism and the persistence of racialized modes of reasoning continue to marginalise black men from this and other powerful, high-status forms of hegemonic masculinity.
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- Authors: Vincent, Louise
- Date: 2006
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141619 , vital:37990 , DOI: 10.1177/1097184X05277694
- Description: In 1994, a democratic government came to power in South Africa for the first time in the country's history. But political transition is never a single event or moment. Rather, it is a continuous process that faces setbacks and contradictions. One of the questions we might ask about a society in transition is to what extent its gender order has changed or is changing. The present paper sets out to read the country's transformation drama through the lens of contested conceptions of South African masculinity. The article is focused on one particular version of masculinity which it terms “rational-intellectual man,” and the argument is that a legacy of racism and the persistence of racialized modes of reasoning continue to marginalise black men from this and other powerful, high-status forms of hegemonic masculinity.
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