List of Titles

Biotechnology from bench to market: the design, scale-up and commercialisation strategy development of a disruptive bioprocess for potable ethanol production

- Dhanani, Karim Colin Hassan

Authors: Dhanani, Karim Colin Hassan
Date: 2015
Language: English
Type: text , Thesis , Masters , MSc
Identifier: http://hdl.handle.net/10962/55863 , vital:26750
Description: The capacity of research institutions to engage in technology transfer activities has important implications on both economic development and technological advancement. This thesis explores the developmental and commercialisation processes involved in the transfer of a potentially disruptive bioprocessing technology for beverage alcohol production. Ethanolic fermentation strategies are of interest due to their global economic importance and their potential to produce clean renewable fuels in the future. Currently used methods are both energetically wasteful and economically inefficient. To this end more effective bioprocessing methods and implementation strategies are required to enable commercially viable decentralised small-scale ethanol production. Perfusion reactors have a number of advantages over batch and other continuous fermentation strategies. This study aimed to develop and study the fermentative efficiency of a perfusion tower bioreactor system at the bench scale, and subsequently through a scale up process to a low level commercial capacity. An HPLC method was developed for the Simultaneous quantification of common fermentation analytes; this was used to determine bench scale fermentation efficacies over an operational period. At steady state the ethanol volumetric productivity of the bench scale bioreactor system was 3.40 g. L-1.h-1, the average yield of ethanol to consumed sugar was 0.467 g.g -1, with an average sugar conversion percentage of 96%. Results showed that the tower perfusion bioreactor was appropriate for high performance ethyl alcohol fermentations. This reactor design was then scaled up to pilot scale and then commercial scale ca pacity. Similar efficienCies were achieved with these larger systems. Based on the process performance data obtained, a commercialisation strategy was developed and market performance was projected. It was found that productivity rates per unit volume were favourable, and the bioreactor system was determined to be very cost effective for a decentralised ethanolic beverage manufacturing model.
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Bitten

- Sullivan, Louella

Authors: Sullivan, Louella
Date: 2015
Subjects: Creative writing (Higher education) , South African poetry (English) -- Study and teaching (Higher) , South African poerty (English) -- 21st century
Language: English
Type: Thesis , Masters , MA
Identifier: vital:5994 , http://hdl.handle.net/10962/d1017778
Description: My poetry investigates the extraordinary in the everyday, exploring my life as a mother and wife, to find the quiet truths that lie there. Using fresh ways of describing familiar experiences, the poems describe tiny, almost-missed moments and voices that have shaped me. Throughout the collection, I imagine my younger selves commenting on my current self and vice versa. Ultimately, my poems use simple words and clean lines to evoke how I feel (and how I want the reader to feel) in each of the moments they describe.
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Black-boxing and the politics of parliamentary oversight in South Africa

- Siebörger, Ian, Adendorff, Ralph D

Authors: Siebörger, Ian , Adendorff, Ralph D
Date: 2015
Subjects: To be catalogued
Language: English
Type: text , book chapter
Identifier: http://hdl.handle.net/10962/433497 , vital:72976 , ISBN 978-9027206565 , https://doi.org/10.1075/dapsac.65
Description: We investigate a parliamentary committee meeting overseeing a randomly chosen state-owned entity, in order to track the processes of knowledge production that occur in parliamentary oversight. The entity’s representatives use “epistemological condensation” (Maton 2014:130) to present the information they give to the MPs as incontestable, effectively “black-boxing” it. “Black-boxing” (Latour 1987) is a process which presents knowledge in such a way that very little room is left for questioning it. The committee members also use “epistemological rarefaction” (Maton 2014:130) to open the black box of the presentation and question its contents, challenging the practices of the entity.
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Book Review Growing the next generation of researchers: A handbook for emerging researchers and their mentors, Holness, L

- Motshoane, Puleng, Muthama, Evelyn, McKenna, Sioux

Authors: Motshoane, Puleng , Muthama, Evelyn , McKenna, Sioux
Date: 2015
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/187205 , vital:44579 , xlink:href="https://doi.org/10.14426/cristal.v3i2.56"
Description: South Africa urgently needs more researchers (NRF, 2008; NDP, 2011). We also need a transformation in the demographics of our researchers. One indicator of this is that currently only 14% of university professors are black African, and only 2% are black African females (DHET, 2012). The Staffing South Africa's Universities Framework includes a number of initiatives to drive the process of growing the next generation of academics. For example, the nGAP project has inserted 125 new posts into the higher education system in 2015, with more to follow. This project allows for new academics to undertake postgraduate study and develop as teachers and researchers through mentorship, a reduced teaching load and so on.
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Book Review: A Renegade called Simphiwe

- Magadla, Siphokazi

Authors: Magadla, Siphokazi
Date: 2015
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/298595 , vital:57719 , xlink:href="https://doi.org/10.1177/0021909614533638"
Description: A Renegade called Simphiwe is a “creative-intellectual portrait” of the public (and private) life of the musician Simphiwe Dana (p. 150). Gqola defines the book as “one writer’s engagement with the Simphiwe Dana of the South African public imagination [who]… troubles many categories of belonging in the South African public imagination in remarkable ways” (pp. 17, 32). The book comes at a poignant time as South Africa reflects on the success and challenges of the first 20 years of democracy. Fittingly, Gqola positions Dana within a long tradition of griots in Africa whose art always spoke truth to power.
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Book Review: Global Governance and the New Wars

- Magadla, Siphokazi

Authors: Magadla, Siphokazi
Date: 2015
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/298640 , vital:57723 , xlink:href="https://doi.org/10.1080/02589346.2015.1008676"
Description: Mark Duffield's second edition of ‘Global Governance and the New Wars’ offers an important and biting critique of how different actors within the security and development discourse have adapted to the various transformations of war in the post-cold war era. In this picture drawn by Duffield, the power of states in the South continues to be eroded by an exclusionary market that is driven by the global political economy wherein state's development and security responsibilities are increasingly assumed by non-state actors (predominately constituted by Western aid agencies). Those who fall outside the bounds of the state, development and humanitarian aid agencies can be found operating in an expanding shadow economy that is also shaped by a global dynamics which make the conditions for ‘network war' possible. In this context, the lines between ‘war' and peace” are difficult to distinguish. Overall, the book paints a depressing picture on the lack of substantive changes in the livelihoods of the poor as attention has been directed to discussions about ‘new wars' or altered forms of violence that have characterized the post-cold war era. The book unforgivingly exposes the failures of the discursive changes post-cold war to reconceptualize development and security in terms that move beyond description and into substantive change especially regarding shifting the development discourse from its historic modernizing impulses.
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Britain after the Romans : an interdisciplinary approach to the possibilities of an Adventus Saxonum

- Lloyd-Jones, Glyn Francis Michael

Authors: Lloyd-Jones, Glyn Francis Michael
Date: 2015
Subjects: Great Britain -- History -- Anglo-Saxon period, 449-1066 , Civilization, Anglo-Saxon , English philology -- Old English, ca. 450-1100 , English literature -- Old English, ca. 450-1100 , Anglo-Saxon race , Genetic genealogy
Language: English
Type: Thesis , Masters , MA
Identifier: vital:3657 , http://hdl.handle.net/10962/d1019806
Description: In the fifth century, after the departure of the Romans, according to tradition, which is based on the ancient written sources, Britain was invaded by the Angles and Saxons. This view has been questioned in the last century. The size of the ‘invasion’, and indeed its very existence, have come into doubt. However, this doubting school of thought does not seem to take into account all of the evidence. An interdisciplinary, nuanced approach has been taken in this thesis. Firstly, the question of Germanic raiding has been examined, with reference to the Saxon Shore defences. It is argued that these defences, in their geographical context, point to the likelihood of raiding. Then the written sources have been re-examined, as well as physical artefacts. In addition to geography, literature and archaeology (the disciplines which are most commonly used when the coming of the Angles and Saxons is investigated), linguistic and genetic data have been examined. The fields of linguistics and genetics, which have not often both been taken into consideration with previous approaches, add a number of valuable insights. This nuanced approach yields a picture of events that rules out the ‘traditional view’ in some ways, such as the idea that the Saxons exterminated the Britons altogether, but corroborates it in other ways. There was an invasion of a kind (of Angles – not Saxons), who came in comparatively small numbers, but found in Britain a society already mixed and comprising Celtic and Germanic-speaking peoples: a society implied by Caesar and Tacitus and corroborated by linguistic and genetic data.
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Brown hyena habitat selection varies among sites in a semi-arid region of southern Africa

- Welch, Rebecca J, Tambling, Craig J, Bissett, Charlene, Gaylard, Angela, Müller, Konrad, Slater, Kerry, Strauss, W Maartin, Parker, Daniel M

Authors: Welch, Rebecca J , Tambling, Craig J , Bissett, Charlene , Gaylard, Angela , Müller, Konrad , Slater, Kerry , Strauss, W Maartin , Parker, Daniel M
Date: 2015
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/123277 , vital:35423 , https://doi.10.1093/jmammal/gyv189
Description: In the last 50 years, the human impact on ecosystems has been greater than during any other time period in human history (Millennium Ecosystem Assessment 2003). Large carnivores face anthropogenic threats worldwide, specifically persecution, habitat degradation, and habitat fragmentation (Everatt et al. 2014; Groom et al. 2014; Ripple et al. 2014; Wolfe et al. 2015). Because large carnivores often occupy high trophic levels, their presence influences species at lower levels through trophic cascades (Ripple et al. 2014). Natural experiments, taking advantage of large carnivore management, have shown that large predators provide fundamental ecosystem and economic services that help maintain healthy and diverse ecosystems (Ripple et al. 2014). Additionally, carnivores play an important role in other ecosystem processes, for example, scavenging carnivores may provide regulatory services, such as waste removal, nutrient cycling, and disease regulation. Such services add stability to ecosystems and ensure energy flow through multiple trophic levels (DeVault et al. 2003; Wilson and Wolkovich 2011).
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Building an E-health system for health awareness campaigns in poor areas

- Gremu, Chikumbutso David

Authors: Gremu, Chikumbutso David
Date: 2015
Subjects: National health services -- South Africa , Medical informatics , Public health -- Information services
Language: English
Type: Thesis , Masters , MSc
Identifier: vital:4708 , http://hdl.handle.net/10962/d1017930
Description: Appropriate e-services as well as revenue generation capabilities are key to the deployment and the sustainability for ICT installations in poor areas, particularly common in developing country. The area of e-Health is a promising area for e-services that are both important to the population in those areas and potentially of direct interest to National Health Organizations, which already spend money for Health campaigns there. This thesis focuses on the design, implementation, and full functional testing of HealthAware, an application that allows health organization to set up targeted awareness campaigns for poor areas. Requirements for such application are very specific, starting from the fact that the preparation of the campaign and its execution/consumption happen in two different environments from a technological and social point of view. Part of the research work done for this thesis was to make the above requirements explicit and then use them in the design. This phase of the research was facilitated by the fact that the thesis' work was executed within the context of the Siyakhula Living Lab (SLL; www.siyakhulaLL.org), which has accumulated multi-year experience of ICT deployment in such areas. As a result of the found requirements, HealthAware comprises two components, which are web-based, Java applications that run in a peer-to-peer fashion. The first component, the Dashboard, is used to create, manage, and publish information for conducting awareness campaigns or surveys. The second component, HealthMessenger, facilitates users' access to the campaigns or surveys that were created using the Dashboard. The HealthMessenger was designed to be hosted on TeleWeaver while the Dashboard is hosted independently of TeleWeaver and simply communicates with the HealthMessenger through webservices. TeleWeaver is an application integration platform developed within the SLL to host software applications for poor areas. Using a core service of TeleWeaver, the profile service, where all the users' defining elements are contained, campaigns and surveys can be easily and effectively targeted, for example to match specific demographics or geographic locations. Revenue generation is attained via the logging of the interactions of the target users in the communities with the applications in TeleWeaver, from which billing data is generated according to the specific contractual agreements with the National Health Organization. From a general point of view, HealthAware contributes to the concrete realizations of a bidirectional access channel between Health Organizations and users in poor communities, which not only allows the communication of appropriate content in both directions, but get 'monetized' and in so doing becomes a revenue generator.
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Can perceptions of environmental and climate change in island communities assist in adaptation planning locally?

- Aswani, Shankar, Vaccaro, Ismael, Abernethy, Kirsten Elizabeth, Albert, Simon, de Pablo, Javier Fernández-López

Authors: Aswani, Shankar , Vaccaro, Ismael , Abernethy, Kirsten Elizabeth , Albert, Simon , de Pablo, Javier Fernández-López
Date: 2015
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/123310 , vital:35426 , https://doi.10.1007/s00267-015-0572-3
Description: Local perceptions of environmental and climate change, as well as associated adaptations made by local populations, are fundamental for designing comprehensive and inclusive mitigation and adaptation plans both locally and nationally. In this paper, we analyze people’s perceptions of environmental and climate-related transformations in communities across the Western Solomon Islands through ethnographic and geospatial methods. Specifically, we documented people’s observed changes over the past decades across various environmental domains, and for each change, we asked respondents to identify the causes, timing, and people’s adaptive responses. We also incorporated this information into a geographical information system database to produce broad-scale base maps of local perceptions of environmental change. Results suggest that people detected changes that tended to be acute (e.g., water clarity, logging intensity, and agricultural diseases). We inferred from these results that most local observations of and adaptations to change were related to parts of environment/ecosystem that are most directly or indirectly related to harvesting strategies. On the other hand, people were less aware of slower insidious/chronic changes identified by scientific studies. For the Solomon Islands and similar contexts in the insular tropics, a broader anticipatory adaptation planning strategy to climate change should include a mix of local scientific studies and local observations of ongoing ecological changes.
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Carbonate petrography and geochemistry of BIF of the Transvaal supergroup : evaluating the potential of iron carbonates as proxies for palaeoproterozoic ocean chemistry

- Rafuza, Sipesihle

Authors: Rafuza, Sipesihle
Date: 2015
Subjects: Carbonate rocks -- South Africa -- Transvaal Supergroup , Petrology -- South Africa -- Transvaal Supergroup , Geochemistry -- South Africa -- Transvaal Supergroup , Petrology -- South Africa -- Kuruman , Petrology -- South Africa -- Griekwastad , Geology, Stratigraphic -- Proterozoic , Chemical oceanography , Iron
Language: English
Type: Thesis , Masters , MSc
Identifier: vital:5089 , http://hdl.handle.net/10962/d1018611
Description: The subject of BIF genesis, particularly their environmental conditions and ocean chemistry at the time of deposition and their evolution through time, has been a subject of much contentiousness, generating a wealth of proposed genetic models and constant refinements thereof over the years. The prevailing paradigm within the various schools of thought, is the widespread and generally agreed upon depositional and diagenetic model(s) which advocate for BIF deposition under anoxic marine conditions. According to the prevailing models, the primary depositional environment would have involved a seawater column whereby soluble Fe²⁺ expelled by hydrothermal activity mixed with free O₂ from the shallow photic zone produced by eukaryotes, forming a high valence iron oxy-hydroxide precursor such as FeOOH or Fe(OH)₃. An alternative biological mechanism producing similar ferric precursors would have been in the form of photo-ferrotrophy, whereby oxidation of ferrous iron to the ferric form took place in the absence of biological O₂ production. Irrespective of the exact mode of primary iron precipitation (which remains contentious to date), the precipitated ferric oxy-hydroxide precursor would have reacted with co-precipitated organic matter, thus acting as a suitable electron acceptor for organic carbon remineralisation through Dissimilatory Iron Reduction (DIR), as also observed in many modern anoxic diagenetic environments. DIR-dominated diagenetic models imply a predominantly diagenetic influence in BIF mineralogy and genesis, and use as key evidence the low δ¹³C values relative to the seawater bicarbonate value of ~0 ‰, which is also thought to have been the dissolved bicarbonate isotope composition in the early Precambrian oceans. The carbon for diagenetic carbonate formation would thus have been sourced through a combination of two end-member sources: pore-fluid bicarbonate at ~0 ‰ and particulate organic carbon at circa -28 ‰, resulting in the intermediate δ¹³C values observed in BIFs today. This study targets 65 drillcore samples of the upper Kuruman and Griquatown BIF from the lower Transvaal Supergroup in the Hotazel area, Northern Cape, South Africa, and sets out to explore key aspects in BIF carbonate petrography and geochemistry that are pertinent to current debates surrounding their interpretation with regard to primary versus diagenetic processes. The focus here rests on applications of carbonate (mainly siderite and ankerite) petrography, mineral chemistry, bulk and mineral-specific carbon isotopes and speciation analyses, with a view to obtaining valuable new insights into BIF carbonates as potential records of ocean chemistry for their bulk carbonate-carbon isotope signature. Evaluation of the present results is done in light of pre-existing, widely accepted diagenetic models against a proposed water-column model for the origin of the carbonate species in BIF. The latter utilises a combination of geochemical attributes of the studied carbonates, including the conspicuous Mn enrichment and stratigraphic variability in Mn/Fe ratio of the Griquatown BIF recorded solely in the carbonate fraction of the rocks. Additionally, the carbon isotope signatures of the Griquatown BIF samples are brought into the discussion and provide insights into the potential causes and mechanisms that may have controlled these signatures in a diagenetic versus primary sedimentary environment. Ultimately, implications of the combined observations, findings and arguments presented in this thesis are presented and discussed with particular respect to the redox evolution and carbon cycle of the ocean system prior to the Great Oxidation Event (GOE). A crucial conclusion reached is that, by contrast to previously-proposed models, diagenesis cannot singularly be the major contributing factor in BIF genesis at least with respect to the carbonate fraction in BIF, as it does not readily explain the carbon isotope and mineral-chemical signatures of carbonates in the Griquatown and uppermost Kuruman BIFs. It is proposed instead that these signatures may well record water-column processes of carbon, manganese and iron cycling, and that carbonate formation in the water column and its subsequent transfer to the precursor BIF sediment constitutes a faithful record of such processes. Corollary to that interpretation is the suggestion that the evidently increasing Mn abundance in the carbonate fraction of the Griquatown BIF up-section would point to a chemically evolving depositional basin with time, from being mainly ferruginous as expressed by Mn-poor BIFs in the lower stratigraphic sections (i.e. Kuruman BF) to more manganiferous as recorded in the upper Griquatown BIF, culminating in the deposition of the abnormally enriched in Mn Hotazel BIF at the stratigraphic top of the Transvaal Supergroup. The Paleoproterozoic ocean must therefore have been characterised by long-term active cycling of organic carbon in the water column in the form of an ancient biological pump, albeit with Fe(III) and subsequently Mn(III,IV) oxy-hydroxides being the key electron acceptors within the water column. The highly reproducible stratigraphic isotope profiles for bulk δ¹³C from similar sections further afield over distances up to 20 km, further corroborate unabatedly that bulk carbonate carbon isotope signatures record water column carbon cycling processes rather than widely-proposed anaerobic diagenetic processes.
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Caring for a child with disabilities: a psychosocial case study

- Saville Young, Lisa, Berry, Jessie

Authors: Saville Young, Lisa , Berry, Jessie
Date: 2015
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/143860 , vital:38289 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
Description: This paper presents a psychosocial analysis of an interview with a mother of a child with disabilities. A psychosocial perspective (conceptualizing the subject as both discursively and psychically constituted) has been argued for recently in critical disability studies by Goodley (2011) who advocates for psychoanalysis’ rich vocabulary for affective processes to explore the emotional elements of disablism, where disablism refers to ways in which society discriminates against people with disabilities (‘barriers out there’). While rejecting the use of psychoanalytic theory to pathologise and individualise people with disabilities, Goodley argues that how “oppression is felt psychically, subjectively and emotionally” (p.716) (‘barriers in here’) should not be overlooked, alongside subjectivity as always socially, politically, culturally and economically produced. This psychosocial analysis of a carer’s perspective thickens our understanding of how the caregiver is a social being, both not disabled but at the receiving end of disablism, and an interpersonal subject who may also be an ‘agent’ or ‘carrier’ of disablism.
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Celebrating libraries in 20 years of democracy : an overview of library and information services in South Africa

- Satgoor, Ujala

Authors: Satgoor, Ujala
Date: 2015
Subjects: Libraries , Library administration -- South Africa , Information services -- South Africa , Public libraries -- South Africa , Library science -- South Africa
Language: English
Type: Article
Identifier: vital:6997 , http://hdl.handle.net/10962/d1019841 , ISSN ISSN: 0340-0352 , http://journals.sagepub.com/doi/10.1177/0340035215585100
Description: Since the establishment of the first public library in 1818, the South African library and information services landscape has also been a reflection of the socio-political order and developments in the country. This article presents an historical perspective as well as an overview of libraries in South Africa since 1994, the context within which libraries function, library governance and legislative framework, government funding for redress, library technologies, library and information services education and the professional association. The article further highlights the importance of libraries in meeting the goals of the national development agenda towards entrenching a strong democracy and an educated and informed nation , Original publication is available at: http://dx.doi.org/10.1177/0340035215585100
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Challenges of post-apartheid state-owned company pension fund reform: a case study of the controversy around the Transnet-Transport Pension Fund

- Goqoza, Noluyolo Juliet

Authors: Goqoza, Noluyolo Juliet
Date: 2015
Language: English
Type: text , Thesis , Masters , MSocSc
Identifier: http://hdl.handle.net/10962/54766 , vital:26610
Description: This thesis examines the restructuring of the pension funds of Transnet, a South African state-owned company involved in transportation, from the 1990s. Two of its main pension funds, the Transport-Transnet Pension sub-Fund (TTPF) and the Transnet Second Defined Benefit Fund (TSDBF), have been surrounded by controversy, with major court actions brought by aggrieved pensioners in 2006-2012 and again from 2013, and smaller cases in 1997-1999 and 2004. (There were also a number of smaller cases, mostly unsuccessful, but the thesis will not examine them). The case that started in 2013 is the biggest class action in the country‟s history, and makes claims of serious mismanagement and bad faith against the Transnet management. But the fundamental grievance is that (according to the 2013 legal case) “more than 80% of pensioners earn less than R4 000.00 a month… 62 % earn less than R2 500.00… 45% of the pensioners earn less than the state‟s ordinary old-age pension” grant for the poor. Although that case is ongoing, this thesis examines the background and controversies that frame the case. It provides an overview of the history and development of the South African pensions system and South African state-owned companies; it examines how these have been shaped by the apartheid and post-apartheid periods, and by the rise of neo-liberalism; it examines the evolution of Transnet and its pensions systems, from the early days of the South African Railways and Harbours Administration (SAR&H, formed 1910), to its restructuring into the South African Transport Services (SATS) in 1982, and then into Transnet in 1990. The thesis shows that the operations of the TTPF and TSDBF, which are closed to new members, have had serious effects on pensioners that rely upon them. Pensions are very low (the main reason for the various court cases), and this is for a range of reasons. Annual increases in pensions are formally set at below-inflation levels, leading to falling real incomes. More pressure on pensioners‟ livelihoods has arisen from Transnet‟s cuts to other benefits, like the medical aid Transmed, provided to pensioners. While the schemes are solvent, the pensions generally started at a low base, partly because most pensioners were relatively poorly paid workers before retirement (and the pensions were linked to former salaries). There is also a racial dimension: while most white workers at SAR&H/ SATS and Transnet were poorly paid, black, Coloured and Indian workers were paid even worse, and, further, were only brought into the pension schemes late. Both TTPF and TSDBF are defined benefit funds, which means members are guaranteed specific benefits at retirement, with the employer obligated to inject funds to meet shortfalls where needed. Yet neither the state nor Transnet has been willing to take actions to lift the basic pensions, such as investments into the funds, or to make systematic ex gratia payments to bring the pensions to a reasonable level, to remove historic racial inequalities between pensioners, to increase medical aid co-payments or coverage or to otherwise address the pensioners‟ situation. It does not seem that the reason for the problems is that the two funds have been severely mismanaged or asset-stripped, as alleged in the 2013 class action: it must be noted that both funds report surpluses. But the surpluses are possible because the pensions are low and falling in real terms, and the numbers of pensioners declining due to deaths. It seems clear that Transnet is unable or unwilling to act to decisively improve the situation of the pensioners: ensuring a surplus on existing pension funds is a major goal. This is partly because Transnet itself has ongoing financial problems, and partly because it operates in the context of neo-liberal restructuring, like corporatisation, commercialisation and privatisation, which places limits on the additional funding of the funds. At the same time, the pensioners have very little real, as opposed to a nominal, say in the administration of the pension schemes, limiting their ability to affect the rules and administration or raise issues. The thesis seeks to use historical institutionalism, which sees policies and major institutions, including state-owned companies, as shaped by power and conflict, especially between classes. This is used to try and explain changing state policies and the changing role and actions of state-owned companies, as a way of understanding Transnet‟s actions, as well as its treatment of its pensioners.
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Change in Roviana Lagoon Coral Reef ethnobiology:

- Aswani, Shankar, Albert, Simon

Authors: Aswani, Shankar , Albert, Simon
Date: 2015
Language: English
Type: text , book
Identifier: http://hdl.handle.net/10962/145460 , vital:38440 , ISBN 9783319237633 , DOI: 10.1007/978-3-319-23763-3_10
Description: Coral reefs are iconic for their beauty and biodiversity, and are of great socioeconomic and cultural importance for many coastal communities across the tropics. However, little is known about people’s local classification and their social and ecological relationship with these habitats. This chapter describes Roviana people’s changing ecological and social relationship with their coral reefs, which are increasingly being damaged by humans. First, we combined ecological and social data to describe people’s classification of local coral reefs in tandem with the productive practices conducted in these habitats. Second, we examined local perceptions and recognized effects of environmental and climatic changes on reefs over the last two decades. Finally, we measured changes in fishing activities and in the taxonomic systems (between 1995 and 2011) to evaluate if recent social and economic change has led to the erosion of marine indigenous ecological knowledge and associated practices. Studying people’s changing perceptions of their coral reefs is crucial to understand their ability to identify and adapt to environmental transformations. Simply, the way local people perceive the state of the environment is not only important in terms of changes in local epistemology but also has important implications for how resources are used and managed, and this information can be coupled with scientific one for a broader management strategy.
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Characterisation of the HSP70-HSP90 organising protein gene and its link to cancer

- Weeks, Stacey

Authors: Weeks, Stacey
Date: 2015
Language: English
Type: text , Thesis , Masters , MSc
Identifier: http://hdl.handle.net/10962/56006 , vital:26764
Description: HOP (Heat shock protein 70/ Heat shock protein 90 organising protein) is a co-chaperone essential for client protein transfer from HSP70 to HSP90 within the HSP90 chaperone machine and has been found to be up-regulated in various cancers. However, minimal in vitro information can be found on the regulation of HOP expression. The aim of this study was to analyse the HOP gene structure across known orthologues, identify and characterise the HOP promoter, and identify the regulatory mechanisms influencing the expression of HOP in cancer. We hypothesized that the expression of HOP in cancer cells is likely regulated by oncogenic signalling pathways linked to cis-elements within the HOP promoter. An initial study of the evolution of the HOP gene speciation was performed across identified orthologues using Mega5.2. The evolutionary pathway of the HOP gene was traced from the unicellular organisms to fish, to amphibian and then to land mammal. The synteny across the orthologues was identified and the co-expression profile of HOP analysed. We identified the putative promoter region for HOP in silico and in vitro. Luciferase reporter assays were utilized to demonstrate promoter activity of the upstream region in vitro. Bioinformatic analysis of the active promoter region identified a large CpG island and a range of putative cis-elements. Many of the cis-elements interact with transcription factors which are activated by oncogenic pathways. We therefore tested the regulation of HOP levels by rat sarcoma viral oncogene homologue (RAS). Cancer cell lines were transfected with mutated RAS to observe the effect of constitutively active RAS expression on the production of HOP using qRT-PCR and Western Blot analyses. Additionally, inhibitors of the RAS signalling pathway were utilised to confirm the regulatory effect of mutated RAS on HOP expression. In cancer cell lines containing mutated RAS (Hs578T), HOP was up-regulated via a mechanism involving the MAPK signalling pathway and the ETS-1 and C/EBPβ cis-elements within the HOP promoter. These findings suggest for the first time that Hop expression in cancer may be regulated by RAS activation of the HOP promoter. Additionally, this study allowed us to determine the murine system to be the most suited genetic model organism with which to study the function of human HOP.
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Characterization and analysis of NTP amplification based DDoS attacks

- Rudman, Lauren, Irwin, Barry V W

Authors: Rudman, Lauren , Irwin, Barry V W
Date: 2015
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/429285 , vital:72573 , 10.1109/ISSA.2015.7335069
Description: Network Time Protocol based DDoS attacks saw a lot of popularity throughout 2014. This paper shows the characterization and analysis of two large datasets containing packets from NTP based DDoS attacks captured in South Africa. Using a series of Python based tools, the dataset is analysed according to specific parts of the packet headers. These include the source IP address and Time-to-live (TTL) values. The analysis found the top source addresses and looked at the TTL values observed for each address. These TTL values can be used to calculate the probable operating system or DDoS attack tool used by an attacker. We found that each TTL value seen for an address can indicate the number of hosts attacking the address or indicate minor routing changes. The Time-to-Live values, as a whole, are then analysed to find the total number used throughout each attack. The most frequent TTL values are then found and show that the migratory of them indicate the attackers are using an initial TTL of 255. This value can indicate the use of a certain DDoS tool that creates packets with that exact initial TTL. The TTL values are then put into groups that can show the number of IP addresses a group of hosts are targeting.
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Characterization of porphyrin nanorods on fluorine doped tin oxide glass sheet

- George, Reama C, Falgenhauer, Jane, Geis, Clemens, Nyokong, Tebello, Schlettwein, Derck

Authors: George, Reama C , Falgenhauer, Jane , Geis, Clemens , Nyokong, Tebello , Schlettwein, Derck
Date: 2015
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/193542 , vital:45344 , xlink:href="https://doi.org/10.1142/S1088424615500923"
Description: Porphyrin nanorods (PNR) have been fabricated by electrostatic self-assembly of two oppositely charged porphyrin molecules. The free base meso-tetra-(4-phenylsulphonate) porphyrin (TPPS4)4) served as negatively charged counterpart for the positively charged metallo meso-tetra(4-NN-methylpyridyl) porphyrins (MTM’PyP) with either Sn, Co, Mn or In as central metal M. Films of PNR were prepared on fluorine doped tin oxide glass sheets (FTO) by using a drop-dry method. The electronic spectra revealed J-aggregation of the charged molecules for the colloid PNR as well as for the films. Transmission electron microscopy confirmed the formation of porphyrin nanorods. The laser microscope and scanning electron microscope (SEM) images of the PNR/FTO films showed the formation of three kinds of structures in the films which consist of differently branched or linear needles with their main axis grown in the direction of the solvent flow during preparation. During cyclic voltammetry either applying negative potentials from 0.0 V to -1.0 V or positive potentials from 0.0 V to ++2.2 V irreversible reduction or oxidation reactions were detected for the films. Consistently, SEM images taken following cyclic voltammetry showed the disintegration of the PNR on the films into smaller subunits. Spectroelectrochemical measurements showed the formation of porphyrin anionic radicals during oxidation by a decrease in the absorption intensities and broadening of spectra with an additional band appearing around 900 nm. A similar trend was observed when negative potentials were applied but in this case the cationic radical was produced. In both cases the decrease of the intensity of the J-aggregate confirms a loss of intermolecular coupling, again consistent with the smaller subunits observed in SEM analysis.
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