Examining the expenditures and retention of money of recreational fishing along the Wild Coast, South Africa
- Authors: Pyle, Michael Jonathan
- Date: 2023-10-13
- Subjects: Ecotourism South Africa , Sustainable fisheries South Africa , Wild Coast Region , Small-scale fisheries Economic aspects South Africa , Socioeconomic development , Leakage
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419673 , vital:71665
- Description: Developing countries and rural communities rely heavily on the ocean for food, transport, and the sustainability of their livelihoods. While the economics of small-scale fisheries in rural areas have received much attention, there is generally less information on the economic contributions from recreational fisheries in these areas. South Africa’s marine recreational fishery is large and contributes to a significant amount of economic activity. However, the retention of money from recreational fishing activities in local rural economies is unknown and thus the potential developmental benefits from this sector remain unquantified. This study examined the economic contributions from recreational fishing along the Wild Coast and retention of expenditures within the local economy. A total of 109 face-to-face economic surveys were administered during the peak recreational fishing season in December 2021. Based on the results, recreational fishing in the Wild Coast has the ability to generate R 415 446 098 in economic activity annually, however only 9.5% of this is retained within local coastal economies, which diminishes the economic contributions of the fishery to the Wild Coast region. Expenditures on items stemming from the informal collection and selling of bait and seafood, domestic work and guiding were the highest locally retained expenditures within the region. 98% of all bait and seafood was harvested and sold by local gillies, with 2% being bought through hotels (n=109). The total direct economic contribution in terms of informal harvesting was estimated at R 16 077 711 for 2021 (n= 9 601). The identification of these contributions can be used to provide recommendations for local economic development strategies which can support the recreational fishery while uplifting coastal communities that should be benefitting more from the activity. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2023
- Full Text:
- Authors: Pyle, Michael Jonathan
- Date: 2023-10-13
- Subjects: Ecotourism South Africa , Sustainable fisheries South Africa , Wild Coast Region , Small-scale fisheries Economic aspects South Africa , Socioeconomic development , Leakage
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419673 , vital:71665
- Description: Developing countries and rural communities rely heavily on the ocean for food, transport, and the sustainability of their livelihoods. While the economics of small-scale fisheries in rural areas have received much attention, there is generally less information on the economic contributions from recreational fisheries in these areas. South Africa’s marine recreational fishery is large and contributes to a significant amount of economic activity. However, the retention of money from recreational fishing activities in local rural economies is unknown and thus the potential developmental benefits from this sector remain unquantified. This study examined the economic contributions from recreational fishing along the Wild Coast and retention of expenditures within the local economy. A total of 109 face-to-face economic surveys were administered during the peak recreational fishing season in December 2021. Based on the results, recreational fishing in the Wild Coast has the ability to generate R 415 446 098 in economic activity annually, however only 9.5% of this is retained within local coastal economies, which diminishes the economic contributions of the fishery to the Wild Coast region. Expenditures on items stemming from the informal collection and selling of bait and seafood, domestic work and guiding were the highest locally retained expenditures within the region. 98% of all bait and seafood was harvested and sold by local gillies, with 2% being bought through hotels (n=109). The total direct economic contribution in terms of informal harvesting was estimated at R 16 077 711 for 2021 (n= 9 601). The identification of these contributions can be used to provide recommendations for local economic development strategies which can support the recreational fishery while uplifting coastal communities that should be benefitting more from the activity. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2023
- Full Text:
The obligation of South Africa to provide social security to refugees and asylum seekers during the COVID-19 pandemic
- Authors: Dekeda, Awethu Zethu
- Date: 2023-10-13
- Subjects: Social security Law and legislation South Africa , Human rights South Africa , Refugees Government policy South Africa , Political refugees South Africa , COVID-19 Pandemic, 2020- Influence
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424119 , vital:72125
- Description: Covid-19 a novel pandemic, has wreaked havoc globally, threatening the livelihoods of all, including refugees and asylum seekers. Like all other countries globally, South Africa has gone to great lengths to mitigate the challenges that this pandemic has caused. However, it is far from clear whether these responses are according due regard to the rights of some of the most vulnerable in society, amongst which are refugees. This thesis deals with South Africa’s obligation to provide social security to refugees during the Covid-19 pandemic. It specifically assesses whether South Africa's responses to the Covid-19 pandemic were in adherence to fundamental refugee law principles relevant to the protection of refugees. The study commences with a general introduction, followed by an analysis of the international human rights and refugee law framework relevant to protection of refugees. This framework is used to assess South Africa’s responses. Subsequently, the discussion delves into South Africa’s own national framework on social security. Using the standards identified in both the national and international frameworks, the thesis then proceeds to measure South Africa’s Covid-19 related responses regarding social security to resolve the issue of whether South Africa adhered to these standards in as far the protection of refugees’ right to social security is concerned. , Thesis (LLM) -- Faculty of Law, Law, 2023
- Full Text:
- Authors: Dekeda, Awethu Zethu
- Date: 2023-10-13
- Subjects: Social security Law and legislation South Africa , Human rights South Africa , Refugees Government policy South Africa , Political refugees South Africa , COVID-19 Pandemic, 2020- Influence
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/424119 , vital:72125
- Description: Covid-19 a novel pandemic, has wreaked havoc globally, threatening the livelihoods of all, including refugees and asylum seekers. Like all other countries globally, South Africa has gone to great lengths to mitigate the challenges that this pandemic has caused. However, it is far from clear whether these responses are according due regard to the rights of some of the most vulnerable in society, amongst which are refugees. This thesis deals with South Africa’s obligation to provide social security to refugees during the Covid-19 pandemic. It specifically assesses whether South Africa's responses to the Covid-19 pandemic were in adherence to fundamental refugee law principles relevant to the protection of refugees. The study commences with a general introduction, followed by an analysis of the international human rights and refugee law framework relevant to protection of refugees. This framework is used to assess South Africa’s responses. Subsequently, the discussion delves into South Africa’s own national framework on social security. Using the standards identified in both the national and international frameworks, the thesis then proceeds to measure South Africa’s Covid-19 related responses regarding social security to resolve the issue of whether South Africa adhered to these standards in as far the protection of refugees’ right to social security is concerned. , Thesis (LLM) -- Faculty of Law, Law, 2023
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The yield spread as a predictor for buy or sell signals for sectoral indices of the JSE
- Authors: Roeber, Christine
- Date: 2023-10-13
- Subjects: Yield curve , Rate of return South Africa , Yield spread , Interest rate , Johannesburg Stock Exchange
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419687 , vital:71666
- Description: The predictive nature of the yield curve has been of interest to researchers for years. In this thesis, the evidence for the yield curve as a predictor is examine, specifically as a predictor for bear markets in the JSE stock market for 8 sub-sectoral indices. The study explores a dynamic market timing strategy for timing the South African stock market compared to a normal buy-and-hold strategy. First, probit models are estimated for each of the sectoral indices which did not prove to have tracked well all the bear market phases. Then a dynamic market timing portfolio is simulated against a buy-and-hold only strategy, the dynamic market timing portfolio proved to have outperformed a buy-and-hold strategy for almost all the indices. Thus, a Henriksson-Merton parametric model test which tests for market timing ability was done on these sub-indices. The research finds that the yield curve in South Africa is not a useful tool for a buy-sell strategy for most of the sub-sectoral indices of the JSE. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2023
- Full Text:
- Authors: Roeber, Christine
- Date: 2023-10-13
- Subjects: Yield curve , Rate of return South Africa , Yield spread , Interest rate , Johannesburg Stock Exchange
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419687 , vital:71666
- Description: The predictive nature of the yield curve has been of interest to researchers for years. In this thesis, the evidence for the yield curve as a predictor is examine, specifically as a predictor for bear markets in the JSE stock market for 8 sub-sectoral indices. The study explores a dynamic market timing strategy for timing the South African stock market compared to a normal buy-and-hold strategy. First, probit models are estimated for each of the sectoral indices which did not prove to have tracked well all the bear market phases. Then a dynamic market timing portfolio is simulated against a buy-and-hold only strategy, the dynamic market timing portfolio proved to have outperformed a buy-and-hold strategy for almost all the indices. Thus, a Henriksson-Merton parametric model test which tests for market timing ability was done on these sub-indices. The research finds that the yield curve in South Africa is not a useful tool for a buy-sell strategy for most of the sub-sectoral indices of the JSE. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2023
- Full Text:
Vulamasango Singene: sociological analysis of a rural social movement
- Authors: Kirchmann, Gail Lynne
- Date: 2023-10-13
- Subjects: Social movements South Africa Eastern Cape , Land reform South Africa , Non-governmental organizations South Africa , Reparations for historical injustices South Africa , Betterments South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/425132 , vital:72213
- Description: This dissertation tests the claim made by a large membership-based organisation that it is a social movement. The organisation, Vulamasango Singene (VS) operates across the rural areas of large parts of the Eastern Cape Province. It has, for twenty years, advocated for the re-opening of land restitution claims for a specific category of forced removal known as “betterment”. This study provides an analysis of an organisation that has yet to achieve its objective in spite of sufficient financial resources, logistical and strategic support, numeric strength and the legal clarity of its demand. The research is situated within the framework of social movement theory. The study examined the origins, institutional infrastructure, demographic make-up, activities and culture of VS. These were analysed against four components that are identified in the literature as key characteristics of a social movement. These are: (i) informal networks (as opposed to structured and managed engagements); (ii) a plurality of actors (as opposed to a homogenous grouping); (iii) mobilising around issues of conflict; and (iv) sharing common beliefs and demonstrating solidarity. Data were gathered through an archival study and field research. Semi-structured interviews were carried out with a sample of VS’s leadership, and staff of the non-governmental organisation in which VS originated, as well as expert informants in the land reform arena. The findings with respect to each of the criteria were: (i) VS’s structure was rigid and internal communication was largely formal. (ii) There was almost no demographic or political diversity within VS. (iii) VS had, in the past, mobilised around issues of conflict, but there had been no mobilisation for ten years. (iv) While there was some evidence of sharing common beliefs and demonstrating solidarity, this was limited. The conclusion reached was that VS is not a social movement. This does not imply that VS is not an important democratic or representative organisation. It does, however, provide a theoretical position from which VS, and other organisations, can direct further action. The study touched on the relationship between northern donors, local professional NGOs and grassroots organisations in South Africa. Interactions among these institutions impact on the way that organisations and social movements develop. Comparisons with other similar organisations were made and similarities and differences were highlighted. It was suggested that, because of the importance of the issue, further research in this regard is necessary. , Thesis (MA) -- Faculty of Humanities, Sociology, 2023
- Full Text:
- Authors: Kirchmann, Gail Lynne
- Date: 2023-10-13
- Subjects: Social movements South Africa Eastern Cape , Land reform South Africa , Non-governmental organizations South Africa , Reparations for historical injustices South Africa , Betterments South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/425132 , vital:72213
- Description: This dissertation tests the claim made by a large membership-based organisation that it is a social movement. The organisation, Vulamasango Singene (VS) operates across the rural areas of large parts of the Eastern Cape Province. It has, for twenty years, advocated for the re-opening of land restitution claims for a specific category of forced removal known as “betterment”. This study provides an analysis of an organisation that has yet to achieve its objective in spite of sufficient financial resources, logistical and strategic support, numeric strength and the legal clarity of its demand. The research is situated within the framework of social movement theory. The study examined the origins, institutional infrastructure, demographic make-up, activities and culture of VS. These were analysed against four components that are identified in the literature as key characteristics of a social movement. These are: (i) informal networks (as opposed to structured and managed engagements); (ii) a plurality of actors (as opposed to a homogenous grouping); (iii) mobilising around issues of conflict; and (iv) sharing common beliefs and demonstrating solidarity. Data were gathered through an archival study and field research. Semi-structured interviews were carried out with a sample of VS’s leadership, and staff of the non-governmental organisation in which VS originated, as well as expert informants in the land reform arena. The findings with respect to each of the criteria were: (i) VS’s structure was rigid and internal communication was largely formal. (ii) There was almost no demographic or political diversity within VS. (iii) VS had, in the past, mobilised around issues of conflict, but there had been no mobilisation for ten years. (iv) While there was some evidence of sharing common beliefs and demonstrating solidarity, this was limited. The conclusion reached was that VS is not a social movement. This does not imply that VS is not an important democratic or representative organisation. It does, however, provide a theoretical position from which VS, and other organisations, can direct further action. The study touched on the relationship between northern donors, local professional NGOs and grassroots organisations in South Africa. Interactions among these institutions impact on the way that organisations and social movements develop. Comparisons with other similar organisations were made and similarities and differences were highlighted. It was suggested that, because of the importance of the issue, further research in this regard is necessary. , Thesis (MA) -- Faculty of Humanities, Sociology, 2023
- Full Text:
Technological pedagogical content knowledge development: investigating secondary school teachers' integration and use of technology during emergency remote teaching in Endola education circuit
- Authors: Munyanyo, Johanna
- Date: 2023-10
- Subjects: Pedagogical content knowledge , Social distancing (Public health) and education , Distance teaching , Educational technology , Technological Pedagogical Content Knowledge
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/423882 , vital:72101
- Description: The Covid-19 pandemic has created the largest disruption of education systems in human history. The closure of schools and other learning spaces has impacted billions of learners worldwide. The mitigative measures and many new standard operating procedures have brought restrictions and many challenges. The face-to-face traditional teaching method lost its value, and teaching shifted to distance through the integration of technologies. The integration of technologies necessitated the emergency remote teaching process, as it is one of the distance teaching modes that can make teaching possible even for less technologically privileged nations. Literature has shown that the integration and usage of technology during teaching support the development of technological pedagogical and content knowledge (TPACK) of teachers. This study, therefore, sought to investigate how the integration and use of technology during the emergency remote teaching of Covid-19 developed the secondary school teachers’ technological pedagogical and content knowledge. The study is underpinned by an interpretive paradigm, and a qualitative case study approach was employed. It was conducted in seven secondary schools in the Endola education circuit, Ohangwena region, with the purposeful participation of twenty-six secondary school teachers. Data was collected using semi-structured questionnaires and semi-structured interviews. The study was informed by Vygotsky’s (1978) sociocultural theory together with the TPACK framework of Thompson and Mishra (2007) as both theoretical and analytical frameworks. The study's results showed that teachers made use of existing technological resources to sustain their teaching efforts during ERT. They encountered various challenges, including a lack of technological expertise (knowledge) among both teachers and learners. The shift to virtual instruction during ERT supported teachers in developing proficient technological pedagogical content knowledge. This research concludes that schools possess the necessary technological infrastructure to enable teachers to incorporate technology into their teaching methods. Furthermore, it highlights that teachers generally hold favourable attitudes toward integrating technology into their instruction. Nevertheless, it recommends that there is a need for improving both in-service and pre-service teachers’ training and support for effectively teaching in online and blended learning environments. , Thesis (MEd) -- Faculty of Education, Secondary and Post-School Education, 2023
- Full Text:
- Authors: Munyanyo, Johanna
- Date: 2023-10
- Subjects: Pedagogical content knowledge , Social distancing (Public health) and education , Distance teaching , Educational technology , Technological Pedagogical Content Knowledge
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/423882 , vital:72101
- Description: The Covid-19 pandemic has created the largest disruption of education systems in human history. The closure of schools and other learning spaces has impacted billions of learners worldwide. The mitigative measures and many new standard operating procedures have brought restrictions and many challenges. The face-to-face traditional teaching method lost its value, and teaching shifted to distance through the integration of technologies. The integration of technologies necessitated the emergency remote teaching process, as it is one of the distance teaching modes that can make teaching possible even for less technologically privileged nations. Literature has shown that the integration and usage of technology during teaching support the development of technological pedagogical and content knowledge (TPACK) of teachers. This study, therefore, sought to investigate how the integration and use of technology during the emergency remote teaching of Covid-19 developed the secondary school teachers’ technological pedagogical and content knowledge. The study is underpinned by an interpretive paradigm, and a qualitative case study approach was employed. It was conducted in seven secondary schools in the Endola education circuit, Ohangwena region, with the purposeful participation of twenty-six secondary school teachers. Data was collected using semi-structured questionnaires and semi-structured interviews. The study was informed by Vygotsky’s (1978) sociocultural theory together with the TPACK framework of Thompson and Mishra (2007) as both theoretical and analytical frameworks. The study's results showed that teachers made use of existing technological resources to sustain their teaching efforts during ERT. They encountered various challenges, including a lack of technological expertise (knowledge) among both teachers and learners. The shift to virtual instruction during ERT supported teachers in developing proficient technological pedagogical content knowledge. This research concludes that schools possess the necessary technological infrastructure to enable teachers to incorporate technology into their teaching methods. Furthermore, it highlights that teachers generally hold favourable attitudes toward integrating technology into their instruction. Nevertheless, it recommends that there is a need for improving both in-service and pre-service teachers’ training and support for effectively teaching in online and blended learning environments. , Thesis (MEd) -- Faculty of Education, Secondary and Post-School Education, 2023
- Full Text:
A review of the Siyakhula Living Lab’s network solution for Internet in marginalized communities
- Muchatibaya, Hilbert Munashe
- Authors: Muchatibaya, Hilbert Munashe
- Date: 2022-10-14
- Subjects: Information and communication technologies for development , Information technology South Africa , Access network , User experience , Local area networks (Computer networks) South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/364943 , vital:65664
- Description: Changes within Information and Communication Technology (ICT) over the past decade required a review of the network layer component deployed in the Siyakhula Living Lab (SLL), a long-term joint venture between the Telkom Centres of Excellence hosted at University of Fort Hare and Rhodes University in South Africa. The SLL overall solution for the sustainable internet in poor communities consists of three main components – the computing infrastructure layer, the network layer, and the e-services layer. At the core of the network layer is the concept of BI, a high-speed local area network realized through easy-to deploy wireless technologies that establish point-to-multipoint connections among schools within a limited geographical area. Schools within the broadband island become then Digital Access Nodes (DANs), with computing infrastructure that provides access to the network. The review, reported in this thesis, aimed at determining whether the model for the network layer was still able to meet the needs of marginalized communities in South Africa, given the recent changes in ICT. The research work used the living lab methodology – a grassroots, user-driven approach that emphasizes co-creation between the beneficiaries and external entities (researchers, industry partners and the government) - to do viability tests on the solution for the network component. The viability tests included lab and field experiments, to produce the qualitative and quantitative data needed to propose an updated blueprint. The results of the review found that the network topology used in the SLL’s network, the BI, is still viable, while WiMAX is now outdated. Also, the in-network web cache, Squid, is no longer effective, given the switch to HTTPS and the pervasive presence of advertising. The solution to the first issue is outdoor Wi-Fi, a proven solution easily deployable in grass-roots fashion. The second issue can be mitigated by leveraging Squid’s ‘bumping’ and splicing features; deploying a browser extension to make picture download optional; and using Pihole, a DNS sinkhole. Hopefully, the revised solution could become a component of South African Government’s broadband plan, “SA Connect”. , Thesis (MSc) -- Faculty of Science, Computer Science, 2022
- Full Text:
- Authors: Muchatibaya, Hilbert Munashe
- Date: 2022-10-14
- Subjects: Information and communication technologies for development , Information technology South Africa , Access network , User experience , Local area networks (Computer networks) South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/364943 , vital:65664
- Description: Changes within Information and Communication Technology (ICT) over the past decade required a review of the network layer component deployed in the Siyakhula Living Lab (SLL), a long-term joint venture between the Telkom Centres of Excellence hosted at University of Fort Hare and Rhodes University in South Africa. The SLL overall solution for the sustainable internet in poor communities consists of three main components – the computing infrastructure layer, the network layer, and the e-services layer. At the core of the network layer is the concept of BI, a high-speed local area network realized through easy-to deploy wireless technologies that establish point-to-multipoint connections among schools within a limited geographical area. Schools within the broadband island become then Digital Access Nodes (DANs), with computing infrastructure that provides access to the network. The review, reported in this thesis, aimed at determining whether the model for the network layer was still able to meet the needs of marginalized communities in South Africa, given the recent changes in ICT. The research work used the living lab methodology – a grassroots, user-driven approach that emphasizes co-creation between the beneficiaries and external entities (researchers, industry partners and the government) - to do viability tests on the solution for the network component. The viability tests included lab and field experiments, to produce the qualitative and quantitative data needed to propose an updated blueprint. The results of the review found that the network topology used in the SLL’s network, the BI, is still viable, while WiMAX is now outdated. Also, the in-network web cache, Squid, is no longer effective, given the switch to HTTPS and the pervasive presence of advertising. The solution to the first issue is outdoor Wi-Fi, a proven solution easily deployable in grass-roots fashion. The second issue can be mitigated by leveraging Squid’s ‘bumping’ and splicing features; deploying a browser extension to make picture download optional; and using Pihole, a DNS sinkhole. Hopefully, the revised solution could become a component of South African Government’s broadband plan, “SA Connect”. , Thesis (MSc) -- Faculty of Science, Computer Science, 2022
- Full Text:
Design, synthesis, manufacture, characterization and evaluation of lipid nanocapsules in chitosan-iota-carrageenan based hydrogel scaffold as a potential anti-Covid-19 drug delivery system
- Authors: Mukubwa, Grady Kathondo
- Date: 2022-10-14
- Subjects: Nanocapsules Design , Hydrogel , COVID-19 (Disease) , Characterization , Drug delivery systems
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/364955 , vital:65665
- Description: Covid-19 is a deadly viral disease that has been rampant around the world since 2019. Although the successful introduction of the vaccine has reduced the spread of covid-19, new cases and deaths are still being recorded. To date, no specific curative antiviral treatment has been approved for covid-19. However, many existing antiviral drugs have been and are still being studied against covid-19 and some of them, such as Remdesivir, have shown promise and could be repurposed to treat this infection. Unfortunately, antiviral drugs are prone to resistance as most of them have poor biopharmaceutical properties, including low solubility, permeability and bioavailability, which could hinder any clinical success. Recent advances in nanotechnology-based delivery systems have made it possible to improve the biopharmaceutical properties of many drugs, especially those of poorly water-soluble drugs, by formulating them as lipid nanoparticles (LNP). Thus, in order to contribute to the fight against covid-19, this work aimed to develop Lipid Nanocapsules (LNC), based on some natural raw materials, which could improve the biopharmaceutical properties of antiviral drugs. In addition, since covid-19 infection is mainly respiratory, this work also aimed to fabricate a targeted delivery system based on a hydrogel capable of entrapping LNC and ensuring their efficient deposition and release in the lungs. The LNC consisted of a mixture of medium-chain triglycerides oil (MCT oil), crude soy lecithin, tween 80, NaCl and water, while the hydrogel consisted of a chitosan-grafted-iota carrageenan-grafted-poly (acrylamide-co-acrylic acid) system (CS-iCar-p (AAm-Co-AA)). Efavirenz (EFV), a drug with very low water solubility that has recently been demonstrated to have the potential to influence sars-cov-2 life cycle through different targets (3CLP, RdRp, Hellicase, 3’to5’exonuclease, 2’-O-ribose methyltransferase and EndoRNAse), was chosen as the model drug to evaluate the developed delivery system. The combination of LNP and hydrogel results in a delivery system known as the LNP-hydrogel composite, an emerging area of research in the field of drug delivery. To date, no research has reported the design and fabrication of an LNC-CS-iCar-p (AAm-Co-AA) hydrogel composite that could effectively deliver an antiviral drug to the lungs in addition to its advantages in terms of biological activities. Prior to the design of experiment, EFV solubility was assessed in water, labrafac lipophile 1349 and MCT oil. After that, the Design Expert Software version 13 was used to design the different experiments performed in this work. The I-optimal mixture design of experiments was performed for both LNC preparation and CS-iCar-p (AAm-Co-AA) hydrogel synthesis to study the impact of raw materials on the characteristics of these delivery systems. LNC were prepared using the phase inversion method while the free radical precipitation graft copolymerization method was used to synthesize hydrogel. In order to build polynomial models that could predict the amount of drug both LNC and CS-iCar-p (AAm-Co-AA) hydrogel can entrap, a D-optimal (custom) randomized design was performed. Moreover, various characterization techniques were used to investigate the physicochemical properties of the developed delivery systems. Thereafter, drug release studies were performed using a 1% sodium lauryl sulfate solution adjusted to either pH 4 or 7. Solubility studies revealed that EFV was more soluble in labrafac lipophile 1349 and in MCT oil than in water; therefore, given its affordability, MCT oil was used for the LNC formulation. The design of experiment carried out allowed the construction of polynomial models that could predict, on the one hand, the droplet size, the polydispersity index and the Zeta potential of LNC, which were respectively around 50nm, below 0.2 and below -33. On the other hand, the model could predict the swelling capacity of the synthesized hydrogel, which was optimised to about 30,000% (300 g of water to 1 g of hydrogel). This turned out to be influenced by the proportion of polymers, the ratio of monomers as well as the concentration of the cross-linking agent. In addition, the characterization techniques further supported the improvement of EFV solubility by highlighting its conversion into its amorphous state after encapsulation in LNC. They also confirmed successful synthesis of CS-iCar-p (AAm-co-AA) hydrogel. LNC were able to encapsulate about 87% of EFV while the synthesized CS-iCar-p (AAm-co-AA) hydrogel entrapped around 53% of EFV encapsulated in LNC. While LNC were able to release 42% and 27% of EFV after 74 hours in a 1% sodium lauryl sulfate solution (SLS) at pH 7 and pH 4 respectively, the LNC-CS-iCar-p (AAm-co-AA) hydrogel composite released about 50% and 40% of the drug after 9 days in the same release medium. Interestingly, the chemical integrity of the drug was preserved throughout the manufacturing process up to after its release, suggesting that the developed LNC-CS-iCar-p (AAm-co-AA) hydrogel composite could be used as a novel potential anticovid-19 drugs delivery system. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Authors: Mukubwa, Grady Kathondo
- Date: 2022-10-14
- Subjects: Nanocapsules Design , Hydrogel , COVID-19 (Disease) , Characterization , Drug delivery systems
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/364955 , vital:65665
- Description: Covid-19 is a deadly viral disease that has been rampant around the world since 2019. Although the successful introduction of the vaccine has reduced the spread of covid-19, new cases and deaths are still being recorded. To date, no specific curative antiviral treatment has been approved for covid-19. However, many existing antiviral drugs have been and are still being studied against covid-19 and some of them, such as Remdesivir, have shown promise and could be repurposed to treat this infection. Unfortunately, antiviral drugs are prone to resistance as most of them have poor biopharmaceutical properties, including low solubility, permeability and bioavailability, which could hinder any clinical success. Recent advances in nanotechnology-based delivery systems have made it possible to improve the biopharmaceutical properties of many drugs, especially those of poorly water-soluble drugs, by formulating them as lipid nanoparticles (LNP). Thus, in order to contribute to the fight against covid-19, this work aimed to develop Lipid Nanocapsules (LNC), based on some natural raw materials, which could improve the biopharmaceutical properties of antiviral drugs. In addition, since covid-19 infection is mainly respiratory, this work also aimed to fabricate a targeted delivery system based on a hydrogel capable of entrapping LNC and ensuring their efficient deposition and release in the lungs. The LNC consisted of a mixture of medium-chain triglycerides oil (MCT oil), crude soy lecithin, tween 80, NaCl and water, while the hydrogel consisted of a chitosan-grafted-iota carrageenan-grafted-poly (acrylamide-co-acrylic acid) system (CS-iCar-p (AAm-Co-AA)). Efavirenz (EFV), a drug with very low water solubility that has recently been demonstrated to have the potential to influence sars-cov-2 life cycle through different targets (3CLP, RdRp, Hellicase, 3’to5’exonuclease, 2’-O-ribose methyltransferase and EndoRNAse), was chosen as the model drug to evaluate the developed delivery system. The combination of LNP and hydrogel results in a delivery system known as the LNP-hydrogel composite, an emerging area of research in the field of drug delivery. To date, no research has reported the design and fabrication of an LNC-CS-iCar-p (AAm-Co-AA) hydrogel composite that could effectively deliver an antiviral drug to the lungs in addition to its advantages in terms of biological activities. Prior to the design of experiment, EFV solubility was assessed in water, labrafac lipophile 1349 and MCT oil. After that, the Design Expert Software version 13 was used to design the different experiments performed in this work. The I-optimal mixture design of experiments was performed for both LNC preparation and CS-iCar-p (AAm-Co-AA) hydrogel synthesis to study the impact of raw materials on the characteristics of these delivery systems. LNC were prepared using the phase inversion method while the free radical precipitation graft copolymerization method was used to synthesize hydrogel. In order to build polynomial models that could predict the amount of drug both LNC and CS-iCar-p (AAm-Co-AA) hydrogel can entrap, a D-optimal (custom) randomized design was performed. Moreover, various characterization techniques were used to investigate the physicochemical properties of the developed delivery systems. Thereafter, drug release studies were performed using a 1% sodium lauryl sulfate solution adjusted to either pH 4 or 7. Solubility studies revealed that EFV was more soluble in labrafac lipophile 1349 and in MCT oil than in water; therefore, given its affordability, MCT oil was used for the LNC formulation. The design of experiment carried out allowed the construction of polynomial models that could predict, on the one hand, the droplet size, the polydispersity index and the Zeta potential of LNC, which were respectively around 50nm, below 0.2 and below -33. On the other hand, the model could predict the swelling capacity of the synthesized hydrogel, which was optimised to about 30,000% (300 g of water to 1 g of hydrogel). This turned out to be influenced by the proportion of polymers, the ratio of monomers as well as the concentration of the cross-linking agent. In addition, the characterization techniques further supported the improvement of EFV solubility by highlighting its conversion into its amorphous state after encapsulation in LNC. They also confirmed successful synthesis of CS-iCar-p (AAm-co-AA) hydrogel. LNC were able to encapsulate about 87% of EFV while the synthesized CS-iCar-p (AAm-co-AA) hydrogel entrapped around 53% of EFV encapsulated in LNC. While LNC were able to release 42% and 27% of EFV after 74 hours in a 1% sodium lauryl sulfate solution (SLS) at pH 7 and pH 4 respectively, the LNC-CS-iCar-p (AAm-co-AA) hydrogel composite released about 50% and 40% of the drug after 9 days in the same release medium. Interestingly, the chemical integrity of the drug was preserved throughout the manufacturing process up to after its release, suggesting that the developed LNC-CS-iCar-p (AAm-co-AA) hydrogel composite could be used as a novel potential anticovid-19 drugs delivery system. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
The effects of strategic planning and oversight on electricity service delivery outcomes in South African local municipalities: a case study of Inxuba Yethemba Municipality
- Authors: Ntintili, Noxolo Indwe
- Date: 2022-10-14
- Subjects: Strategic planning South Africa , Strategic management , Municipal services South Africa , Local government South Africa , Local service delivery , Public sector , Oversight
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408693 , vital:70517
- Description: Poor service delivery in South Africa is a widely researched phenomenon. Yet despite the existing knowledge production efforts, in a context of a progressive developmental municipal legislative framework, South African municipalities continue to be plagued with corruption and poor service delivery performance. This thesis aims to transcend the tendency to attribute poor service delivery to a sole cause (e.g. corruption) by explaining the effects of strategic planning and oversight on several municipal service delivery processes. Therefore, this thesis introduces the Municipal Public Resource Management (MPRM) model as a strategic management tool to explain the relationship between strategic planning, the practical implementation of municipal services, and oversight processes. Specifically, thesis triangulates legislative mandates, documents published by Inxuba Yethemba Municipality (IYM) and responses from semi-structured interviews conducted with three municipal officials and three Municipal Public Accounts Committee (MPAC) councillors to uncover descriptions and explanations of service delivery processes in IYM. Findings from this thesis confirm that poor strategic planning and weak oversight contributed to poor electricity service delivery outcomes in IYM in the 2018/19 – 2019/20 financial year, and this highlights the importance of implementing strategic management for improved service delivery in South African local municipalities. , Thesis (MSocSci) -- Faculty of Humanities, Sociology, 2022
- Full Text:
- Authors: Ntintili, Noxolo Indwe
- Date: 2022-10-14
- Subjects: Strategic planning South Africa , Strategic management , Municipal services South Africa , Local government South Africa , Local service delivery , Public sector , Oversight
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408693 , vital:70517
- Description: Poor service delivery in South Africa is a widely researched phenomenon. Yet despite the existing knowledge production efforts, in a context of a progressive developmental municipal legislative framework, South African municipalities continue to be plagued with corruption and poor service delivery performance. This thesis aims to transcend the tendency to attribute poor service delivery to a sole cause (e.g. corruption) by explaining the effects of strategic planning and oversight on several municipal service delivery processes. Therefore, this thesis introduces the Municipal Public Resource Management (MPRM) model as a strategic management tool to explain the relationship between strategic planning, the practical implementation of municipal services, and oversight processes. Specifically, thesis triangulates legislative mandates, documents published by Inxuba Yethemba Municipality (IYM) and responses from semi-structured interviews conducted with three municipal officials and three Municipal Public Accounts Committee (MPAC) councillors to uncover descriptions and explanations of service delivery processes in IYM. Findings from this thesis confirm that poor strategic planning and weak oversight contributed to poor electricity service delivery outcomes in IYM in the 2018/19 – 2019/20 financial year, and this highlights the importance of implementing strategic management for improved service delivery in South African local municipalities. , Thesis (MSocSci) -- Faculty of Humanities, Sociology, 2022
- Full Text:
English additional language student teachers’ development of oral strategic competence and confidence
- Authors: Meyers, Rozanne Elanore
- Date: 2022-04-08
- Subjects: Student teaching South Africa , Communicative competence South Africa , Oral communication , Native language and education , Language arts , Verbal ability , Multilingual education
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/263613 , vital:53643
- Description: This case study sought to understand how oral strategic and discourse competence and confidence developed in student teachers using English, their additional language, firstly as a tool of learning and secondly, as a medium of instruction in education environments. Within the broad qualitative approach an interpretive framework was adopted using multiple data collection tools. This was in order to privilege detailed accounts of participants’ experiences. Namely, unstructured interviews, drawings, observational checklists, and selfassessment questionnaires. Participants’ oral strategic and discourse competence were assessed using an observation checklist as they presented micro-teaching lessons. Additionally, participants completed a self-assessment questionnaire, reflecting on their oral competence after conducting their micro-teaching lessons. These perceptions were confirmed through a discussion of drawings that illustrated how they perceived themselves during lectures when they had to use English during oral interaction with lecturers and fellow students. Finally, unstructured interviews were conducted after participants completed their micro-teaching lessons and after participants had completed their drawings. The raw data from the four tools were analysed using a thematic approach. Main themes and categories were analysed and discussed to provide answers to the research questions. Data correlated the attitude of participants towards English and their level of oral confidence and competence. The main findings were that students were motivated to develop their oral English competence because they believed it was an important skill for teachers to possess. This motivation also proved to be a leading factor in participants’ competence despite the negative emotions they identified during spoken exchanges. Furthermore, the analysis found that collaborating with fellow students in making meaning of oral communication during lectures, increased students’ oral competence and their confidence because they were communicating in smaller groups. However, in certain situations, collaborating with students also decreased their confidence. Findings indicated that reciprocal facial expressions and the body language of those who engaged orally with the student teachers, increased their oral confidence as it served as an indication to them that they were understood. Based on these findings, recommendations are made regarding interactions during lectures for teacher training programmes in Higher Education in South Africa, for lecturers and lecturing practices, and curriculum designers in the South African Department of Education. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
- Authors: Meyers, Rozanne Elanore
- Date: 2022-04-08
- Subjects: Student teaching South Africa , Communicative competence South Africa , Oral communication , Native language and education , Language arts , Verbal ability , Multilingual education
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/263613 , vital:53643
- Description: This case study sought to understand how oral strategic and discourse competence and confidence developed in student teachers using English, their additional language, firstly as a tool of learning and secondly, as a medium of instruction in education environments. Within the broad qualitative approach an interpretive framework was adopted using multiple data collection tools. This was in order to privilege detailed accounts of participants’ experiences. Namely, unstructured interviews, drawings, observational checklists, and selfassessment questionnaires. Participants’ oral strategic and discourse competence were assessed using an observation checklist as they presented micro-teaching lessons. Additionally, participants completed a self-assessment questionnaire, reflecting on their oral competence after conducting their micro-teaching lessons. These perceptions were confirmed through a discussion of drawings that illustrated how they perceived themselves during lectures when they had to use English during oral interaction with lecturers and fellow students. Finally, unstructured interviews were conducted after participants completed their micro-teaching lessons and after participants had completed their drawings. The raw data from the four tools were analysed using a thematic approach. Main themes and categories were analysed and discussed to provide answers to the research questions. Data correlated the attitude of participants towards English and their level of oral confidence and competence. The main findings were that students were motivated to develop their oral English competence because they believed it was an important skill for teachers to possess. This motivation also proved to be a leading factor in participants’ competence despite the negative emotions they identified during spoken exchanges. Furthermore, the analysis found that collaborating with fellow students in making meaning of oral communication during lectures, increased students’ oral competence and their confidence because they were communicating in smaller groups. However, in certain situations, collaborating with students also decreased their confidence. Findings indicated that reciprocal facial expressions and the body language of those who engaged orally with the student teachers, increased their oral confidence as it served as an indication to them that they were understood. Based on these findings, recommendations are made regarding interactions during lectures for teacher training programmes in Higher Education in South Africa, for lecturers and lecturing practices, and curriculum designers in the South African Department of Education. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
Stock market volatility during times of crisis: a comparative analysis of the conditional volatilities of JSE stock indices during the 2007/08 global financial crisis and COVID-19
- Authors: Wang, Zixiao
- Date: 2022-04-06
- Subjects: Stock exchanges , Johannesburg Stock Exchange , Global Financial Crisis, 2008-2009 , COVID-19 (Disease) Economic aspects , Economic forecasting , Stock exchanges and current events , GARCH model
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284603 , vital:56078
- Description: This research analyses the comparative behaviour of stock market volatility during two crises. The goal of this research is to determine whether assumed cyclical and defensive sectors have either retained or revealed their expected properties during both the Global Financial Crisis (GFC) and COVID-19 by analysing sectoral volatility amid these two crises. Understanding how volatility changes amid crises helps to determine whether the volatility assumptions of diversified investment portfolios for both defensive and cyclical sectors still held given the different causes of each crisis. In turn, this knowledge can assist with risk management and portfolio allocation in stock market investments. The study can also contribute towards the enhancement of financial markets’ resistance against systemic risks through portfolio diversification, and aid government decision-making targeted at tackling the weaknesses of different economic sectors especially in times of overall economic weakness. This research makes use of the GARCH model to analyse a group of daily time series that consists of eleven sectoral indices and one benchmark index, all based on the South African stock markets. These observed series are categorised into two full sample periods, one designated to the Global Financial Crisis (January 2006 to May 2009) and the other for COVID-19 (January 2018 to May 2021). These are further divided into two sets of sub-sample periods, each made up of a pre-crisis and during-crisis. Furthermore, the dummy variables representing the occurrence of structural breaks are inserted into the full sample periods’ conditional variance equations. This is aimed at capturing the asymmetrical impact of the crises themselves on all observed series. Based on the movement of volatility persistency from pre-crisis to during-crisis for both crises, the results show that, firstly, Health Care and Consumer Goods are considered defensive Sectors. Secondly, Banks, Basic Materials, Chemicals, Telecommunications, and Financials are considered cyclical Sectors. Thirdly, Automobiles & Parts, Consumer Services, and Technology are considered indeterminable Sectors due to the inconsistent behaviour of these sectors’ volatility persistency throughout the sub-sample periods of both crises. Overall, according to the average volatility persistency, the observed series for COVID-19’s full sample period are generally less volatile than those of the GFC. However, the sub-sample periods suggest that the observed series for both pre-crisis and during-crisis periods of COVID-19 are more volatile than those same sub-samples of the Global Financial Crisis. Being able to analyse the characteristics of stock market sectors is crucial for risk management and optimal portfolio allocation of stock market investments. This can be achieved through portfolio diversification by investing in a variety of stocks, both cyclical and defensive, and adjusted over time based the needs of stock market investors. Diversified portfolios do not only serve the interests of individual investors, but can also enhance the financial markets’ overall resistance against systemic risks. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2022
- Full Text:
- Authors: Wang, Zixiao
- Date: 2022-04-06
- Subjects: Stock exchanges , Johannesburg Stock Exchange , Global Financial Crisis, 2008-2009 , COVID-19 (Disease) Economic aspects , Economic forecasting , Stock exchanges and current events , GARCH model
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284603 , vital:56078
- Description: This research analyses the comparative behaviour of stock market volatility during two crises. The goal of this research is to determine whether assumed cyclical and defensive sectors have either retained or revealed their expected properties during both the Global Financial Crisis (GFC) and COVID-19 by analysing sectoral volatility amid these two crises. Understanding how volatility changes amid crises helps to determine whether the volatility assumptions of diversified investment portfolios for both defensive and cyclical sectors still held given the different causes of each crisis. In turn, this knowledge can assist with risk management and portfolio allocation in stock market investments. The study can also contribute towards the enhancement of financial markets’ resistance against systemic risks through portfolio diversification, and aid government decision-making targeted at tackling the weaknesses of different economic sectors especially in times of overall economic weakness. This research makes use of the GARCH model to analyse a group of daily time series that consists of eleven sectoral indices and one benchmark index, all based on the South African stock markets. These observed series are categorised into two full sample periods, one designated to the Global Financial Crisis (January 2006 to May 2009) and the other for COVID-19 (January 2018 to May 2021). These are further divided into two sets of sub-sample periods, each made up of a pre-crisis and during-crisis. Furthermore, the dummy variables representing the occurrence of structural breaks are inserted into the full sample periods’ conditional variance equations. This is aimed at capturing the asymmetrical impact of the crises themselves on all observed series. Based on the movement of volatility persistency from pre-crisis to during-crisis for both crises, the results show that, firstly, Health Care and Consumer Goods are considered defensive Sectors. Secondly, Banks, Basic Materials, Chemicals, Telecommunications, and Financials are considered cyclical Sectors. Thirdly, Automobiles & Parts, Consumer Services, and Technology are considered indeterminable Sectors due to the inconsistent behaviour of these sectors’ volatility persistency throughout the sub-sample periods of both crises. Overall, according to the average volatility persistency, the observed series for COVID-19’s full sample period are generally less volatile than those of the GFC. However, the sub-sample periods suggest that the observed series for both pre-crisis and during-crisis periods of COVID-19 are more volatile than those same sub-samples of the Global Financial Crisis. Being able to analyse the characteristics of stock market sectors is crucial for risk management and optimal portfolio allocation of stock market investments. This can be achieved through portfolio diversification by investing in a variety of stocks, both cyclical and defensive, and adjusted over time based the needs of stock market investors. Diversified portfolios do not only serve the interests of individual investors, but can also enhance the financial markets’ overall resistance against systemic risks. , Thesis (MCom) -- Faculty of Commerce, Economics and Economic History, 2022
- Full Text:
Educating learners with special educational needs in special schools: an interpretative phenomenological study of teachers’ experiences
- Authors: Matebese, Sibongile
- Date: 2021-10-29
- Subjects: Children with disabilities Education South Africa , South Africa. Department of Education , Inclusive education South Africa , Special education teachers South Africa , Special education teachers South Africa Interviews , Phenomenological psychology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192270 , vital:45211
- Description: In 2001, the Department of Education introduced a policy known as White Paper 6: Special Needs Education: Building an Inclusive Education and Training System. This policy was a response to the worldwide call for inclusive education. It aimed to ensure that all learners with special educational needs (LSEN) and who experience barriers to learning are accommodated and taught in mainstream schooling contexts. Implementation of this policy in South Africa has been a challenge, and special schools continue to exist. While research has explored the experiences of teachers who teach LSEN, such studies have focused on teacher experiences in mainstream schools. A few international and South African studies have explored teacher experiences of teaching LSEN in special schools; however, these explore specific aspects of teacher experiences and are outdated. Based on this premise and drawing on a phenomenological approach, this study sought to explore and understand the experiences of teachers who teach LSEN in special schools. Using the semi-structured interview, eight teachers teaching in special schools in a city in the Eastern Cape were recruited and interviewed. Five superordinate themes emerged from the shared experiences, namely, ‘personal commitment and the need for a balance’, ‘recognising the learner at the centre’, ‘the importance of a holistic approach’, ‘the ups and downs of teaching LSEN’, and ‘support is available but limited’. Within these themes, the teachers experienced teaching LSEN as involving more than teaching, as a role guided by the learner, as collaborative, associated with positive experiences and challenges, including an endeavour that they are adequately supported in but simultaneously require more support for. In reflecting on this analysis, this study argues that special schools are necessary; teaching LSEN in special schools is important to teachers, and they feel a responsibility for it. Recommendations for future research include repeating the present study with a different population and methodology, interviewing parents of LSEN and LSEN themselves to gain further insights into special schooling. The study makes key recommendations for special needs education to help ensure that such an educational system is sustained as inclusion is a long way from being realised. , Thesis (MA) -- Faculty of Humanities, Psychology, 2021
- Full Text:
- Authors: Matebese, Sibongile
- Date: 2021-10-29
- Subjects: Children with disabilities Education South Africa , South Africa. Department of Education , Inclusive education South Africa , Special education teachers South Africa , Special education teachers South Africa Interviews , Phenomenological psychology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192270 , vital:45211
- Description: In 2001, the Department of Education introduced a policy known as White Paper 6: Special Needs Education: Building an Inclusive Education and Training System. This policy was a response to the worldwide call for inclusive education. It aimed to ensure that all learners with special educational needs (LSEN) and who experience barriers to learning are accommodated and taught in mainstream schooling contexts. Implementation of this policy in South Africa has been a challenge, and special schools continue to exist. While research has explored the experiences of teachers who teach LSEN, such studies have focused on teacher experiences in mainstream schools. A few international and South African studies have explored teacher experiences of teaching LSEN in special schools; however, these explore specific aspects of teacher experiences and are outdated. Based on this premise and drawing on a phenomenological approach, this study sought to explore and understand the experiences of teachers who teach LSEN in special schools. Using the semi-structured interview, eight teachers teaching in special schools in a city in the Eastern Cape were recruited and interviewed. Five superordinate themes emerged from the shared experiences, namely, ‘personal commitment and the need for a balance’, ‘recognising the learner at the centre’, ‘the importance of a holistic approach’, ‘the ups and downs of teaching LSEN’, and ‘support is available but limited’. Within these themes, the teachers experienced teaching LSEN as involving more than teaching, as a role guided by the learner, as collaborative, associated with positive experiences and challenges, including an endeavour that they are adequately supported in but simultaneously require more support for. In reflecting on this analysis, this study argues that special schools are necessary; teaching LSEN in special schools is important to teachers, and they feel a responsibility for it. Recommendations for future research include repeating the present study with a different population and methodology, interviewing parents of LSEN and LSEN themselves to gain further insights into special schooling. The study makes key recommendations for special needs education to help ensure that such an educational system is sustained as inclusion is a long way from being realised. , Thesis (MA) -- Faculty of Humanities, Psychology, 2021
- Full Text:
Investigation of sediment buffering function of the Gatberg Floodplain Wetland in the upper Tsitsa River Catchment, South Africa
- Pakati, Sibuyisele Sweetness
- Authors: Pakati, Sibuyisele Sweetness
- Date: 2021-10
- Subjects: Sedimentation and deposition South Africa Eastern Cape , Sediment transport South Africa Eastern Cape , Floodplain morphology South Africa Eastern Cape , Wetlands South Africa Eastern Cape , Suspended sediments South Africa Eastern Cape , Floods South Africa Eastern Cape , Fluvial geomorphology South Africa Eastern Cape , Floodplain plants South Africa Eastern Cape , Inundation depth
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190792 , vital:45028
- Description: Floodplain wetlands are important components of river systems that provide various ecosystem services such as sediment buffering. These wide and often expansive storage areas have a substantial impact on downstream water quality by trapping sediment and storing ‘contaminants’ adhered to sediment thus improving water quality. The planned construction of the Ntabelanga and Lalini Dams in the Tsitsa River Catchment has been proposed; however, due to the steep landscapes and erodible soils, this promotes high erosion rates that can potentially reduce the lifespan of the proposed dams. The existing wetlands in the Tsitsa River Catchment have therefore been identified as key sediment buffers that can reduce sediment transport, but the effectiveness of these buffers is poorly researched. This study attempts to investigate the current sediment buffering function of the Gatberg Floodplain Wetland over one wet season (August 2019 to August 2020). Time integrated samplers were installed above and below the wetland to determine relative sediment volume and character coming in and out of the wetland. Five transects were surveyed across the wetland width to evaluate the topography and vegetation characteristics. Surface sediment samples on the floodplain were taken at key morphological features along each transect and along the river longitudinal profile to determine organic content, particle size, and type of stored sediment. Astro turf mats were deployed on targeted transects and on key floodplain features to determine sediment accumulation rates. Field measurements of vegetation parameters (height, density, and stem diameter) were taken to calculate vegetation-induced hydraulic roughness to understand possible sedimentation feedbacks. The relative sediment volume coming into the wetland was greater than that leaving the wetland. This implies that some of the sediment is buffered within the wetland. An approximate proportion of 73% trapping efficiency of the incoming sediment was buffered within the floodplain wetland during the wet season. This accumulated approximately 4 tons within the wetland over the monitoring frame. Bed particle size in the longitudinal profile increased with distance downstream, this was due to localized tributary and hillslope inputs. Inundation depth varied across the floodplain wetland with deeper inundation depths at the head of the wetland than at the bottom; where particle size was larger with an increase in water level depth. This may be linked to both high stream velocities and variability of the floodplain topography. However, the observed trends were inconclusive and uncertain. Stronger correlations with particle size were shown by vegetation roughness (b* = 0.41) and distance from the channel (b* = -0.38). Flood benches and banks had a coarser D50 particle size than back swamps and oxbows. Coarser sediment in flood benches are associated with proximity to the sediment-laden water that experiences abrupt flow velocity changes, while finer material in oxbows are due to minimal flow velocities which reduce with distance from the channel. Finer particles remain in suspension and are carried aloft for longer periods at very low velocities. Therefore, particle size decreased with distance from the channel due to longer travel distances and high surface area relative to weight. Further results showed that finer surface sediment particle size was associated with high vegetation roughness whilst coarser material was associated with low roughness. This was due to vegetation geometry and type or changes in flow velocity and energy. Grassy vegetation induced finer particle size than shrubby vegetation that has a greater line spacing. Furthermore, vegetation roughness varied over the wet season; roughness was highest in late summer and low in early summer. Low roughness was due to fire occurrence in the study area which resulted in a decrease in biomass. Increasing vegetation roughness can be due to increased flood events, and the introduction of non-perennial species; which can increase sediment accumulation rates. Although studies have shown that vegetation density is the most essential factor affecting flow resistance and sedimentation processes; vegetation height and stem diameter for this study area seem to contrast these observations and rather may be the most significant contributing factors in sedimentation. This concluded that vegetation density may not always be the most essential component in sedimentation processes. Sediment particle size was inversely proportional to organic content; finer particle size are more cohesive and more capable of carrying organics. Regions further away from the channel such as oxbows with stable moisture conditions favour plant growth and soil formation thus are susceptible to high organic content. Flood benches are closer to the channel, thus have coarser material and fluctuating moisture conditions that have unstable high water flow velocities. High sediment accumulation rates on flood benches and oxbows is due to high connectivity to sediment-laden water and high hydroperiods or high residence time for sediment accumulation in oxbows. Sediment accumulation rate was shown to be a function of particle size itself (b* = 0.67) rather than the expected vegetation roughness. Although a true representation of sediment accumulation rates in the Gatberg Wetland was limited by the disturbance of astro turf mats by animals and possibly by high flooding events; the wetland can be regarded as a good sediment buffer as some sediment was stored (e.g. up to 48,04 kg/m2 in flood benches) within the wetland over the monitoring period. , Thesis (MSc) -- Faculty of Science, Geography, 2021
- Full Text:
- Authors: Pakati, Sibuyisele Sweetness
- Date: 2021-10
- Subjects: Sedimentation and deposition South Africa Eastern Cape , Sediment transport South Africa Eastern Cape , Floodplain morphology South Africa Eastern Cape , Wetlands South Africa Eastern Cape , Suspended sediments South Africa Eastern Cape , Floods South Africa Eastern Cape , Fluvial geomorphology South Africa Eastern Cape , Floodplain plants South Africa Eastern Cape , Inundation depth
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190792 , vital:45028
- Description: Floodplain wetlands are important components of river systems that provide various ecosystem services such as sediment buffering. These wide and often expansive storage areas have a substantial impact on downstream water quality by trapping sediment and storing ‘contaminants’ adhered to sediment thus improving water quality. The planned construction of the Ntabelanga and Lalini Dams in the Tsitsa River Catchment has been proposed; however, due to the steep landscapes and erodible soils, this promotes high erosion rates that can potentially reduce the lifespan of the proposed dams. The existing wetlands in the Tsitsa River Catchment have therefore been identified as key sediment buffers that can reduce sediment transport, but the effectiveness of these buffers is poorly researched. This study attempts to investigate the current sediment buffering function of the Gatberg Floodplain Wetland over one wet season (August 2019 to August 2020). Time integrated samplers were installed above and below the wetland to determine relative sediment volume and character coming in and out of the wetland. Five transects were surveyed across the wetland width to evaluate the topography and vegetation characteristics. Surface sediment samples on the floodplain were taken at key morphological features along each transect and along the river longitudinal profile to determine organic content, particle size, and type of stored sediment. Astro turf mats were deployed on targeted transects and on key floodplain features to determine sediment accumulation rates. Field measurements of vegetation parameters (height, density, and stem diameter) were taken to calculate vegetation-induced hydraulic roughness to understand possible sedimentation feedbacks. The relative sediment volume coming into the wetland was greater than that leaving the wetland. This implies that some of the sediment is buffered within the wetland. An approximate proportion of 73% trapping efficiency of the incoming sediment was buffered within the floodplain wetland during the wet season. This accumulated approximately 4 tons within the wetland over the monitoring frame. Bed particle size in the longitudinal profile increased with distance downstream, this was due to localized tributary and hillslope inputs. Inundation depth varied across the floodplain wetland with deeper inundation depths at the head of the wetland than at the bottom; where particle size was larger with an increase in water level depth. This may be linked to both high stream velocities and variability of the floodplain topography. However, the observed trends were inconclusive and uncertain. Stronger correlations with particle size were shown by vegetation roughness (b* = 0.41) and distance from the channel (b* = -0.38). Flood benches and banks had a coarser D50 particle size than back swamps and oxbows. Coarser sediment in flood benches are associated with proximity to the sediment-laden water that experiences abrupt flow velocity changes, while finer material in oxbows are due to minimal flow velocities which reduce with distance from the channel. Finer particles remain in suspension and are carried aloft for longer periods at very low velocities. Therefore, particle size decreased with distance from the channel due to longer travel distances and high surface area relative to weight. Further results showed that finer surface sediment particle size was associated with high vegetation roughness whilst coarser material was associated with low roughness. This was due to vegetation geometry and type or changes in flow velocity and energy. Grassy vegetation induced finer particle size than shrubby vegetation that has a greater line spacing. Furthermore, vegetation roughness varied over the wet season; roughness was highest in late summer and low in early summer. Low roughness was due to fire occurrence in the study area which resulted in a decrease in biomass. Increasing vegetation roughness can be due to increased flood events, and the introduction of non-perennial species; which can increase sediment accumulation rates. Although studies have shown that vegetation density is the most essential factor affecting flow resistance and sedimentation processes; vegetation height and stem diameter for this study area seem to contrast these observations and rather may be the most significant contributing factors in sedimentation. This concluded that vegetation density may not always be the most essential component in sedimentation processes. Sediment particle size was inversely proportional to organic content; finer particle size are more cohesive and more capable of carrying organics. Regions further away from the channel such as oxbows with stable moisture conditions favour plant growth and soil formation thus are susceptible to high organic content. Flood benches are closer to the channel, thus have coarser material and fluctuating moisture conditions that have unstable high water flow velocities. High sediment accumulation rates on flood benches and oxbows is due to high connectivity to sediment-laden water and high hydroperiods or high residence time for sediment accumulation in oxbows. Sediment accumulation rate was shown to be a function of particle size itself (b* = 0.67) rather than the expected vegetation roughness. Although a true representation of sediment accumulation rates in the Gatberg Wetland was limited by the disturbance of astro turf mats by animals and possibly by high flooding events; the wetland can be regarded as a good sediment buffer as some sediment was stored (e.g. up to 48,04 kg/m2 in flood benches) within the wetland over the monitoring period. , Thesis (MSc) -- Faculty of Science, Geography, 2021
- Full Text:
In silico identification of selective novel hits against the active site of wild type mycobacterium tuberculosis pyrazinamidase and its mutants
- Authors: Gowo, Prudence
- Date: 2021-04
- Subjects: Mycobacterium tuberculosis , Pyrazinamide , Multidrug resistance , Antitubercular agents , Molecular dynamics , Hydrogen bonding , Ligand binding (Biochemistry) , Dynamic Residue Network
- Language: English
- Type: thesis , text , Masters , MSc
- Identifier: http://hdl.handle.net/10962/178007 , vital:42898
- Description: The World Health Organization declared Tuberculosis a global health emergency and has set a goal to eradicate it by 2035. However, effective treatment and control of the disease is being hindered by the emerging Multi-Drug Resistant and Extensively Drug Resistant strains on the most effective first line prodrug, Pyrazinamide (PZA). Studies have shown that the main cause of PZA resistance is due to mutations in the pncA gene that codes for the target protein Pyrazinamidase (PZase). Therefore, this study aimed to identify novel drug compounds that bind to the active site of wild type PZase and study the dynamics of these potential anti-TB drugs in the mutant systems of PZase. This approach will aid in identifying drugs that may be repurposed for TB therapy and/or designed to counteract PZA resistance. This was achieved by screening 2089 DrugBank compounds against the whole wild type (WT) PZase protein in molecular docking using AutoDOCK4.2. Compound screening based on docking binding energy, hydrogen bonds, molecular weight and active site proximity identified 47 compounds meeting all the set selection criteria. The stability of these compounds were analysed in Molecular Dynamic (MD) simulations and were further studied in PZase mutant systems of A3P, A134V, A146V, D8G, D49A, D49G, D63G, H51P, H137R, L85R, L116R, Q10P, R140S, T61P, V139M and Y103S. Generally, mutant-ligand systems displayed little deviation from the WT systems. The compound systems remained compact, with less fluctuations and more hydrogen bond interactions throughout the simulation (DB00255, DB00655, DB00672, DB00782, DB00977, DB01196, DB04573, DB06414, DB08981, DB11181, DB11760, DB13867, DB13952). From this research study, potential drugs that may be repurposed for TB therapy were identified. Majority of these drugs are currently used in the treatment of hypertension, menopause disorders and inflammation. To further understand the mutant-ligand dynamic systems, calculations such as Dynamic Residue Network (DRN) may be done. Also, the bioactivity of these drugs on Mycobacterium tuberculosis may be studied in wet laboratory, to understand their clinical impart in vivo experiments. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2021
- Full Text:
- Authors: Gowo, Prudence
- Date: 2021-04
- Subjects: Mycobacterium tuberculosis , Pyrazinamide , Multidrug resistance , Antitubercular agents , Molecular dynamics , Hydrogen bonding , Ligand binding (Biochemistry) , Dynamic Residue Network
- Language: English
- Type: thesis , text , Masters , MSc
- Identifier: http://hdl.handle.net/10962/178007 , vital:42898
- Description: The World Health Organization declared Tuberculosis a global health emergency and has set a goal to eradicate it by 2035. However, effective treatment and control of the disease is being hindered by the emerging Multi-Drug Resistant and Extensively Drug Resistant strains on the most effective first line prodrug, Pyrazinamide (PZA). Studies have shown that the main cause of PZA resistance is due to mutations in the pncA gene that codes for the target protein Pyrazinamidase (PZase). Therefore, this study aimed to identify novel drug compounds that bind to the active site of wild type PZase and study the dynamics of these potential anti-TB drugs in the mutant systems of PZase. This approach will aid in identifying drugs that may be repurposed for TB therapy and/or designed to counteract PZA resistance. This was achieved by screening 2089 DrugBank compounds against the whole wild type (WT) PZase protein in molecular docking using AutoDOCK4.2. Compound screening based on docking binding energy, hydrogen bonds, molecular weight and active site proximity identified 47 compounds meeting all the set selection criteria. The stability of these compounds were analysed in Molecular Dynamic (MD) simulations and were further studied in PZase mutant systems of A3P, A134V, A146V, D8G, D49A, D49G, D63G, H51P, H137R, L85R, L116R, Q10P, R140S, T61P, V139M and Y103S. Generally, mutant-ligand systems displayed little deviation from the WT systems. The compound systems remained compact, with less fluctuations and more hydrogen bond interactions throughout the simulation (DB00255, DB00655, DB00672, DB00782, DB00977, DB01196, DB04573, DB06414, DB08981, DB11181, DB11760, DB13867, DB13952). From this research study, potential drugs that may be repurposed for TB therapy were identified. Majority of these drugs are currently used in the treatment of hypertension, menopause disorders and inflammation. To further understand the mutant-ligand dynamic systems, calculations such as Dynamic Residue Network (DRN) may be done. Also, the bioactivity of these drugs on Mycobacterium tuberculosis may be studied in wet laboratory, to understand their clinical impart in vivo experiments. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2021
- Full Text:
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