Prevalence and risk factors of imaging confirmed neurological complication amongst patients withhypertensive disorders in pregnancy admitted at Nelson Mandela Academic Hospital
- Authors: Sabona, Ncumisa
- Date: 2023-00
- Subjects: Medicine
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9868 , vital:74635
- Description: Hypertensive disorders in pregnancy (HDP) are the world's second leading cause of maternal mortality and morbidity, with sub-Saharan Africa taking the lead. The prevalence of HDP in Africa is 10%, remarkably higher than the reported global range of 5.2-8%. This study aimed to determine the prevalence and associated risk factors of CT-confirmed neurological complications in patients managed at the labour ward at Nelson Mandela Academic Hospital (NMAH) over two years. Methodology: A retrospective cross-sectional study was conducted on obstetric patients with clinical files at NMAH from January 2018 to December 2020. We tracked and merged hospital admission data and radiological (brain CT) findings in patients managed for HDP at the labour ward at NMAH within the specified period. Descriptive analysis, bivariate and multivariate logistic regression analysis was performed to identify associated clinical risk predictors of neurological complications. Major findings: Of the 5119 patients with HDP, 153 underwent CT scans. Our study found that 78.2% of the scanned patients with HDP were between 18 and 34 years old. Patients younger than 18 years accounted for 10% of the 154 patients who underwent CT-scan. We found that 81.1% had abnormal CT-brain findings, while 18.9% were normal. The most common abnormal finding was posterior reversible encephalopathy syndrome (PRES) (25.1%), followed by cytotoxic oedema (16,5%), neurocysticercosis (15.1%), and dural sinus thrombosis (7.9%). The most common neurological findings on admission were headache (82%), low GCS (60.1%), fits (55.6%), blindness (28.8%), and focal signs (11.5%). In addition, the following risk predictors were statistically associated with PRES: post-partum onset ( aOR=6.26,95% CI 1.02-38.83, p-value0.049 ), blindness (aOR=3.19, 95% CI; 1.07-9.59, p=0.038) and fits (aOR=0.20, 95% CI: 0.64-0.63, p-value=0.006. Recommendations and clinical implications: The most common radiological finding among obstetric patients with HDP in this study is PRES. The most significant risk predictors for PRES are the post-partum onset of symptoms and blindness. As PRES is | 3 associated with significant morbidity and mortality, vigilance and aggressive management should be continued and include the post-partum period. , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
- Authors: Sabona, Ncumisa
- Date: 2023-00
- Subjects: Medicine
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9868 , vital:74635
- Description: Hypertensive disorders in pregnancy (HDP) are the world's second leading cause of maternal mortality and morbidity, with sub-Saharan Africa taking the lead. The prevalence of HDP in Africa is 10%, remarkably higher than the reported global range of 5.2-8%. This study aimed to determine the prevalence and associated risk factors of CT-confirmed neurological complications in patients managed at the labour ward at Nelson Mandela Academic Hospital (NMAH) over two years. Methodology: A retrospective cross-sectional study was conducted on obstetric patients with clinical files at NMAH from January 2018 to December 2020. We tracked and merged hospital admission data and radiological (brain CT) findings in patients managed for HDP at the labour ward at NMAH within the specified period. Descriptive analysis, bivariate and multivariate logistic regression analysis was performed to identify associated clinical risk predictors of neurological complications. Major findings: Of the 5119 patients with HDP, 153 underwent CT scans. Our study found that 78.2% of the scanned patients with HDP were between 18 and 34 years old. Patients younger than 18 years accounted for 10% of the 154 patients who underwent CT-scan. We found that 81.1% had abnormal CT-brain findings, while 18.9% were normal. The most common abnormal finding was posterior reversible encephalopathy syndrome (PRES) (25.1%), followed by cytotoxic oedema (16,5%), neurocysticercosis (15.1%), and dural sinus thrombosis (7.9%). The most common neurological findings on admission were headache (82%), low GCS (60.1%), fits (55.6%), blindness (28.8%), and focal signs (11.5%). In addition, the following risk predictors were statistically associated with PRES: post-partum onset ( aOR=6.26,95% CI 1.02-38.83, p-value0.049 ), blindness (aOR=3.19, 95% CI; 1.07-9.59, p=0.038) and fits (aOR=0.20, 95% CI: 0.64-0.63, p-value=0.006. Recommendations and clinical implications: The most common radiological finding among obstetric patients with HDP in this study is PRES. The most significant risk predictors for PRES are the post-partum onset of symptoms and blindness. As PRES is | 3 associated with significant morbidity and mortality, vigilance and aggressive management should be continued and include the post-partum period. , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
Academic distress & disordered eating in students during the Covid-19 pandemic: a cross-sectional study at a South African university
- Authors: Du Toit, Mae
- Date: 2021-10-29
- Subjects: COVID-19 Pandemic, 2020- Influence , Eating disorders , College students Attitudes , College students Mental health , Stress (Psychology)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/192626 , vital:45244
- Description: University students are at risk for reduced mental wellbeing, particularly during the Covid-19 pandemic, and among the most common problems experienced are academic distress and eating concerns. Through a stress-coping model lens, a link between academic distress and disordered eating in student populations appears possible but has not previously been explored. The present study examines this relationship in a South African undergraduate sample. Data were collected during the Covid-19 pandemic using a cross-sectional, correlational survey design and the Counseling Center Assessment of Psychological Symptoms (CCAPS). The results of a multiple regression analysis indicate that academic distress most strongly predicts eating concerns, followed by the demographic variables of female gender and black racial identification. This novel finding suggests that academic institutions should consider the broader academic environment as point of intervention for the prevention and treatment of disordered eating in students. , Thesis (MA) -- Faculty of Humanities, Psychology, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Du Toit, Mae
- Date: 2021-10-29
- Subjects: COVID-19 Pandemic, 2020- Influence , Eating disorders , College students Attitudes , College students Mental health , Stress (Psychology)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/192626 , vital:45244
- Description: University students are at risk for reduced mental wellbeing, particularly during the Covid-19 pandemic, and among the most common problems experienced are academic distress and eating concerns. Through a stress-coping model lens, a link between academic distress and disordered eating in student populations appears possible but has not previously been explored. The present study examines this relationship in a South African undergraduate sample. Data were collected during the Covid-19 pandemic using a cross-sectional, correlational survey design and the Counseling Center Assessment of Psychological Symptoms (CCAPS). The results of a multiple regression analysis indicate that academic distress most strongly predicts eating concerns, followed by the demographic variables of female gender and black racial identification. This novel finding suggests that academic institutions should consider the broader academic environment as point of intervention for the prevention and treatment of disordered eating in students. , Thesis (MA) -- Faculty of Humanities, Psychology, 2021
- Full Text:
- Date Issued: 2021-10-29
Men in Women’s Clothes
- Authors: Jones, Ward E
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/275658 , vital:55067 , xlink:href="https://doi.org/10.1111/sjp.12394"
- Description: The descriptive phrase that comprises my title can refer both to a pervasive comic trope and a mode of self-expression. There is a tension here, insofar as the comic trope leads us not to take cross-dressing, or drag, seriously. The first half of the comic film Some Like It Hot (1959), with its cross-gender plot and its (sophisticated but) straightforward use of the comic trope of men-in-women’s clothes, appears to fall foul of this tension and to be susceptible to criticism in this regard. However, the film rectifies itself, portraying the cross-dressing relationship which develops through the second half of the film as a potentially meaningful one for both partners. In this article, I interpret the film as inviting its viewers to adopt a (particular kind of) skeptical ironic (that is, Pyrrhonian) attitude toward gender-presentation practices. While the film in no way attempts to discourage us from participating in such practices, it does invite us—through our partiality toward the characters Osgood and Jerry/Daphne, as we follow their budding, transgressive relationship—to acknowledge that a violation of gender-presentation practices can be a meaningful feature of sincere relationships.
- Full Text:
- Date Issued: 2020
- Authors: Jones, Ward E
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/275658 , vital:55067 , xlink:href="https://doi.org/10.1111/sjp.12394"
- Description: The descriptive phrase that comprises my title can refer both to a pervasive comic trope and a mode of self-expression. There is a tension here, insofar as the comic trope leads us not to take cross-dressing, or drag, seriously. The first half of the comic film Some Like It Hot (1959), with its cross-gender plot and its (sophisticated but) straightforward use of the comic trope of men-in-women’s clothes, appears to fall foul of this tension and to be susceptible to criticism in this regard. However, the film rectifies itself, portraying the cross-dressing relationship which develops through the second half of the film as a potentially meaningful one for both partners. In this article, I interpret the film as inviting its viewers to adopt a (particular kind of) skeptical ironic (that is, Pyrrhonian) attitude toward gender-presentation practices. While the film in no way attempts to discourage us from participating in such practices, it does invite us—through our partiality toward the characters Osgood and Jerry/Daphne, as we follow their budding, transgressive relationship—to acknowledge that a violation of gender-presentation practices can be a meaningful feature of sincere relationships.
- Full Text:
- Date Issued: 2020
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