Investigation of α-aryl substituted 3-indolylethanones as potential antiplasmodial agents
- Authors: Svogie, Archibald Lesley
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/55487 , vital:26704
- Description: According to the World Health Organisation (WHO), deaths attributed to Plasmodium falciparum exceeded 584 000 in 2013, with 198 million new cases of malaria being reported. One contributing factor to these alarming figures is the emergence of drug resistance against available antimalarial agents. Therefore, there is a pressing need to develop new therapeutic antimalarial drugs with novel mechanisms of action in order to curb the increasing spread of malaria. The indole scaffold is often associated with biologically active compounds, recently exemplified by the antimalarial agent NITD609, which is currently in phase 1 clinical trials. Based on the biological evaluation of a small series of indolyl-3-amides and esters which showed moderate antimalarial activity, coupled to significant toxicity, we were prompted to investigate the synthesis of a series of indolyl-3-ethanone-α-amines (3.37 and 3.41), ethers (3.39 and 3.44) and thioethers (3.42, 3.43, 3.40, 3.45 – 3.73), where the carbonyl moiety and respective heteroatom were separated by a methine spacer. We further investigated these compounds for in vitro biological activity against P. falciparum and a human HeLa cell line. Our study explored the synthetic pathway of a three-step procedure toward our target compounds, with the initial Friedel-Crafts acetylation of indole, followed by α-bromination of the respective 3-acetylindoles. Finally, the halogen of the α-bromo ketone was substituted with an appropriate nucleophile, to yield our desired compounds. Various reagents were explored to optimise the nucleophilic displacement step, including potassium carbonate and various silver containing compounds. While many of the silver salts were found to assist in nucleophilic substitution, none were superior to the addition of potassium carbonate. The majority of compounds, chiefly the thioethers, displayed promising antimalarial activity, against the chloroquine sensitive 3D7 P. falciparum strain, with two thioethers in particular (3.54 and 3.65) inhibiting P. falciparum in the low nanomolar range. Additionally, active compounds were generally found to be non-toxic against HeLa cells, indicating that indolyl-3-thioethers are selective for the malaria parasite. These findings allowed us to begin hypothesising a structure activity relationship of this class, as well as elucidating the possible pharmacophore. In a speculative attempt to uncover the possible mechanism of action of these active compounds, in silico docking studies were conducted against Staphylococcus aureus HPPK (PDB ID: 4CRJ), which is an enzyme that immediately precedes DHPS in the microbial folate biosynthesis. Inhibition of folate biosynthesis is a validated selective antimalarial pathway and HPPK also exists in P. falciparum. Results from these docking studies suggested that our inhibitors bound well in the HPPK ATP pocket and were supportive of our hypothesized structure activity relationship.
- Full Text:
- Authors: Svogie, Archibald Lesley
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/55487 , vital:26704
- Description: According to the World Health Organisation (WHO), deaths attributed to Plasmodium falciparum exceeded 584 000 in 2013, with 198 million new cases of malaria being reported. One contributing factor to these alarming figures is the emergence of drug resistance against available antimalarial agents. Therefore, there is a pressing need to develop new therapeutic antimalarial drugs with novel mechanisms of action in order to curb the increasing spread of malaria. The indole scaffold is often associated with biologically active compounds, recently exemplified by the antimalarial agent NITD609, which is currently in phase 1 clinical trials. Based on the biological evaluation of a small series of indolyl-3-amides and esters which showed moderate antimalarial activity, coupled to significant toxicity, we were prompted to investigate the synthesis of a series of indolyl-3-ethanone-α-amines (3.37 and 3.41), ethers (3.39 and 3.44) and thioethers (3.42, 3.43, 3.40, 3.45 – 3.73), where the carbonyl moiety and respective heteroatom were separated by a methine spacer. We further investigated these compounds for in vitro biological activity against P. falciparum and a human HeLa cell line. Our study explored the synthetic pathway of a three-step procedure toward our target compounds, with the initial Friedel-Crafts acetylation of indole, followed by α-bromination of the respective 3-acetylindoles. Finally, the halogen of the α-bromo ketone was substituted with an appropriate nucleophile, to yield our desired compounds. Various reagents were explored to optimise the nucleophilic displacement step, including potassium carbonate and various silver containing compounds. While many of the silver salts were found to assist in nucleophilic substitution, none were superior to the addition of potassium carbonate. The majority of compounds, chiefly the thioethers, displayed promising antimalarial activity, against the chloroquine sensitive 3D7 P. falciparum strain, with two thioethers in particular (3.54 and 3.65) inhibiting P. falciparum in the low nanomolar range. Additionally, active compounds were generally found to be non-toxic against HeLa cells, indicating that indolyl-3-thioethers are selective for the malaria parasite. These findings allowed us to begin hypothesising a structure activity relationship of this class, as well as elucidating the possible pharmacophore. In a speculative attempt to uncover the possible mechanism of action of these active compounds, in silico docking studies were conducted against Staphylococcus aureus HPPK (PDB ID: 4CRJ), which is an enzyme that immediately precedes DHPS in the microbial folate biosynthesis. Inhibition of folate biosynthesis is a validated selective antimalarial pathway and HPPK also exists in P. falciparum. Results from these docking studies suggested that our inhibitors bound well in the HPPK ATP pocket and were supportive of our hypothesized structure activity relationship.
- Full Text:
Potential benefits and experienced challenges of small household biogas-digesters for rural households
- Authors: Langley, Kyle Anthony
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4789 , http://hdl.handle.net/10962/d1021268
- Description: Access to renewable energy supplies is a critical foundation for sustainable development and poverty alleviation. Anaerobic biogas-digesters also referred to as bio-digesters, have been identified as one of the leading technologies with regards to assisting in improving energy access for remote rural areas that still remain dependent upon biomass usage. This thesis assesses the potential feasibility of bio-digesters for rural households in South Africa by focusing on the experiences of a remote and rural community in Eastern Cape. A standardised survey was used to capture household details and energy use patterns of households with 180 interviews being conducted. Field observations were also conducted on the five bio-digesters installed in the community over a three month period. Despite the predominance of electrification in the community, households were heavily reliant upon biomass in the form of fuelwood and cattle dung to supplement their energy needs. Households supplemented their energy usage with alternative energy sources such as LPG gas and paraffin, especially during periods when electricity was unavailable or deemed too expensive. Initial knowledge of bio-digester technology in the community was non-existent, however with the installation of bio-digesters within the targeted villages, social learning was observed. Despite low temperatures bio-digesters continued to function throughout the study period, though malfunctions did occur and gas production did not reach optimal levels. Primary challenges encountered were the lack of financial subsidies for wide-spread adoption; the limited technical capacity of the community to conduct repairs and minimal gas production due to a build-up of ligneous materials within the gas chamber of the bio-digesters. Bio-digesters were found to provide significant benefits for households and further studies into maximising their effectiveness for rural South African households are recommended.
- Full Text:
- Authors: Langley, Kyle Anthony
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4789 , http://hdl.handle.net/10962/d1021268
- Description: Access to renewable energy supplies is a critical foundation for sustainable development and poverty alleviation. Anaerobic biogas-digesters also referred to as bio-digesters, have been identified as one of the leading technologies with regards to assisting in improving energy access for remote rural areas that still remain dependent upon biomass usage. This thesis assesses the potential feasibility of bio-digesters for rural households in South Africa by focusing on the experiences of a remote and rural community in Eastern Cape. A standardised survey was used to capture household details and energy use patterns of households with 180 interviews being conducted. Field observations were also conducted on the five bio-digesters installed in the community over a three month period. Despite the predominance of electrification in the community, households were heavily reliant upon biomass in the form of fuelwood and cattle dung to supplement their energy needs. Households supplemented their energy usage with alternative energy sources such as LPG gas and paraffin, especially during periods when electricity was unavailable or deemed too expensive. Initial knowledge of bio-digester technology in the community was non-existent, however with the installation of bio-digesters within the targeted villages, social learning was observed. Despite low temperatures bio-digesters continued to function throughout the study period, though malfunctions did occur and gas production did not reach optimal levels. Primary challenges encountered were the lack of financial subsidies for wide-spread adoption; the limited technical capacity of the community to conduct repairs and minimal gas production due to a build-up of ligneous materials within the gas chamber of the bio-digesters. Bio-digesters were found to provide significant benefits for households and further studies into maximising their effectiveness for rural South African households are recommended.
- Full Text:
The dynamics of police regulation of sexual abuse of children in South Africa: the case of Grahamstown, Eastern Cape
- Authors: Van Blerk, Natasha
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: http://hdl.handle.net/10962/3828 , vital:20546
- Description: This thesis investigates the current legislation and police protocols set in South Africa, specifically regarding their adequacy in protecting the country’s children from sexual abuse. It focuses on relevant legislative provisions and protocols, on sexual abuse of children and on an empirical study conducted amongst a variety of officials who represent the South African legislation at different levels. Trends, developments and problems are analysed and brought forward to raise an awareness on the severity of the issue of child sexual abuse. In addition, this thesis explores how the diversity within the community of Grahamstown, South Africa, should be considered to a higher degree in the legislation. There is a clear indication of a prevalent patriarchal hierarchy within the community which, in reality, makes women and children more vulnerable to sexual abuse. The methods used in this thesis involves purposive sampling, which led to one on one interviews between the researcher and participant. Thisthesis concludes with confirmation of the hypothesis whereby the South African legislation is not adequately protecting the rights of children in regards to sexual abuse. However, to fully adapt the legislation and make it as versatile and as effective the State hopes it to be, it is necessary to understand the society’s perception on women and children and to rectify it. As difficult as this may sound, it all begins with a strong and influential government.
- Full Text:
- Authors: Van Blerk, Natasha
- Date: 2016
- Language: English
- Type: Thesis , Masters , MSocSc
- Identifier: http://hdl.handle.net/10962/3828 , vital:20546
- Description: This thesis investigates the current legislation and police protocols set in South Africa, specifically regarding their adequacy in protecting the country’s children from sexual abuse. It focuses on relevant legislative provisions and protocols, on sexual abuse of children and on an empirical study conducted amongst a variety of officials who represent the South African legislation at different levels. Trends, developments and problems are analysed and brought forward to raise an awareness on the severity of the issue of child sexual abuse. In addition, this thesis explores how the diversity within the community of Grahamstown, South Africa, should be considered to a higher degree in the legislation. There is a clear indication of a prevalent patriarchal hierarchy within the community which, in reality, makes women and children more vulnerable to sexual abuse. The methods used in this thesis involves purposive sampling, which led to one on one interviews between the researcher and participant. Thisthesis concludes with confirmation of the hypothesis whereby the South African legislation is not adequately protecting the rights of children in regards to sexual abuse. However, to fully adapt the legislation and make it as versatile and as effective the State hopes it to be, it is necessary to understand the society’s perception on women and children and to rectify it. As difficult as this may sound, it all begins with a strong and influential government.
- Full Text:
The phytogeography of Southern Mistbelt Forests of the Eastern Cape, South Africa
- Authors: Matiwane, Aviwe
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3224 , vital:20393
- Description: In the Eastern Cape, a moisture gradient (from west to east) exists along the Escarpment where patches of Southern Mistbelt Forests (SMF) occur. There is a notable profusion of plants in these forests, but the factors that drive plant species composition and abundance in these patches is poorly understood and such knowledge is critical if we are to address or mitigate the problems imposed by global change. Many of our ideas on plant community assembly are based on the premise that species differ in their environmental requirements for successful regeneration, especially when young. The aims of this study were to document the floristic diversity of poorly known patches of Southern Mistbelt Forests in the Eastern Cape and identify the environmental factors that influence plant community composition in these forest patches. Twenty six forest patches across the Eastern Cape were sampled. In each forest 400m2 circular plots were constructed. The diameter at breast height and stem counts for the tree species was taken and the % cover of the herbaceous species was recorded. General collections were also made to supplement the plot data in order to obtain a comprehensive flora for each forest patch. All sampling was done during the summer season of 2013 and 2014. Using plot data, Hierarchal Cluster Analysis and Multidimensional Scaling Analysis were done to compare similarities between patches. Plots from the same forest patch clustered which indicated that the species composition in each forest patch was unique. However, this pattern went down when only tree species were considered. Plant diversity also varied between patches; with those located in the east being generally more diverse than those in the west are. Clustering patterns in fragmented communities and differences in species diversity indicate evidence of species “nestedness”. Analysis of nestedness indicated that these forest patches were significantly nested. To identify which environmental variables might be correlated with both species diversity and nestedness, twelve environmental variables was selected for analysis using Canonical Correspondence Analysis and Principal Component Analysis. Results show that Mean Annual Precipitation, Mean Annual Potential Evapotranspiration, and percentage of Organic Matter of the soil were most strongly correlated with the patterns of diversity observed in these forest patches. Regression analysis indicated that Mean Annual Precipitation accounted for most of the variation in species diversity, especially for the herbaceous species. The herbaceous species thus show a greater sensitivity to “climate filtering” as a consequence of rainfall gradients. With the implementation of suitable monitoring programs, changes in abundance or even local extinction of these species can act as an early warning indicator of the possible long-term effects of climate change on forest communities.
- Full Text:
- Authors: Matiwane, Aviwe
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/3224 , vital:20393
- Description: In the Eastern Cape, a moisture gradient (from west to east) exists along the Escarpment where patches of Southern Mistbelt Forests (SMF) occur. There is a notable profusion of plants in these forests, but the factors that drive plant species composition and abundance in these patches is poorly understood and such knowledge is critical if we are to address or mitigate the problems imposed by global change. Many of our ideas on plant community assembly are based on the premise that species differ in their environmental requirements for successful regeneration, especially when young. The aims of this study were to document the floristic diversity of poorly known patches of Southern Mistbelt Forests in the Eastern Cape and identify the environmental factors that influence plant community composition in these forest patches. Twenty six forest patches across the Eastern Cape were sampled. In each forest 400m2 circular plots were constructed. The diameter at breast height and stem counts for the tree species was taken and the % cover of the herbaceous species was recorded. General collections were also made to supplement the plot data in order to obtain a comprehensive flora for each forest patch. All sampling was done during the summer season of 2013 and 2014. Using plot data, Hierarchal Cluster Analysis and Multidimensional Scaling Analysis were done to compare similarities between patches. Plots from the same forest patch clustered which indicated that the species composition in each forest patch was unique. However, this pattern went down when only tree species were considered. Plant diversity also varied between patches; with those located in the east being generally more diverse than those in the west are. Clustering patterns in fragmented communities and differences in species diversity indicate evidence of species “nestedness”. Analysis of nestedness indicated that these forest patches were significantly nested. To identify which environmental variables might be correlated with both species diversity and nestedness, twelve environmental variables was selected for analysis using Canonical Correspondence Analysis and Principal Component Analysis. Results show that Mean Annual Precipitation, Mean Annual Potential Evapotranspiration, and percentage of Organic Matter of the soil were most strongly correlated with the patterns of diversity observed in these forest patches. Regression analysis indicated that Mean Annual Precipitation accounted for most of the variation in species diversity, especially for the herbaceous species. The herbaceous species thus show a greater sensitivity to “climate filtering” as a consequence of rainfall gradients. With the implementation of suitable monitoring programs, changes in abundance or even local extinction of these species can act as an early warning indicator of the possible long-term effects of climate change on forest communities.
- Full Text:
An exploration of business level strategy at the bottom of the pyramid: a case study of Twizza, Eastern Cape
- Authors: Sityoshwana, Ludwe Lusu
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/54486 , vital:26569
- Description: This qualitative study focuses on business level strategy adopted by Twizza to compete in the bottom of the pyramid market in the Eastern Cape, South Africa. Twizza enjoyed huge success between the years 2010 - 2014 as a medium to large sized manufacturer of carbonated soft drinks in the Eastern Cape. In light of this, the current study seeks to answer the following: What business level strategy did top management at Twizza adopt to compete and grow in the BoP market in the Eastern Cape, South Africa? The study takes the form of a case study to explore and understand the patterns of decisions adopted by Twizza’s top management in competing at the bottom of the pyramid. As such, the main objective of the study was to identify the business level strategy adopted by Twizza which enabled their superior performance within the BoP market. The study adopts Porter`s typology to explore business level strategy. Stratified, purposive sampling was used to identify 4 top managers as participants in this study. A total of 7, semi-structured, interviews were used to collect critical incidents from top management of Twizza. This was the primary data used in this study. This type of data was combined with relevant information which was gathered via published press articles and on-line commentary. The study found that central to Twizza’s business strategy were four pillars, namely, strict control and management of manufacturing costs, product quality equal to that of market leaders, the ability of the organisation to manufacture its own raw materials and ability to ensure product availability to the market to the market. These findings reveal that Twizza employed a hybrid strategy, anchored by cost leadership. Thus, Twizza incorporated elements of differentiation and best value strategies to offer its customers affordable quality.
- Full Text:
- Authors: Sityoshwana, Ludwe Lusu
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/54486 , vital:26569
- Description: This qualitative study focuses on business level strategy adopted by Twizza to compete in the bottom of the pyramid market in the Eastern Cape, South Africa. Twizza enjoyed huge success between the years 2010 - 2014 as a medium to large sized manufacturer of carbonated soft drinks in the Eastern Cape. In light of this, the current study seeks to answer the following: What business level strategy did top management at Twizza adopt to compete and grow in the BoP market in the Eastern Cape, South Africa? The study takes the form of a case study to explore and understand the patterns of decisions adopted by Twizza’s top management in competing at the bottom of the pyramid. As such, the main objective of the study was to identify the business level strategy adopted by Twizza which enabled their superior performance within the BoP market. The study adopts Porter`s typology to explore business level strategy. Stratified, purposive sampling was used to identify 4 top managers as participants in this study. A total of 7, semi-structured, interviews were used to collect critical incidents from top management of Twizza. This was the primary data used in this study. This type of data was combined with relevant information which was gathered via published press articles and on-line commentary. The study found that central to Twizza’s business strategy were four pillars, namely, strict control and management of manufacturing costs, product quality equal to that of market leaders, the ability of the organisation to manufacture its own raw materials and ability to ensure product availability to the market to the market. These findings reveal that Twizza employed a hybrid strategy, anchored by cost leadership. Thus, Twizza incorporated elements of differentiation and best value strategies to offer its customers affordable quality.
- Full Text:
Teacher leadership practice : a case study of a public primary school in a semi-urban area of the Otjozondjupa Region, central Namibia
- Authors: Hanghuwo, Maria Nahambo
- Date: 2015
- Subjects: Democracy and education -- Study and teaching (Elementary) -- Namibia , Educational leadership , Teacher participation in administration
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2030 , http://hdl.handle.net/10962/d1017341
- Description: The education system in Namibia was shaped by the policies located within the framework of the apartheid ideology. Since it gained its independence in 1990, the government positioned education at the top of the national priorities. Thus, there has been a growing realisation of the importance of more democratic forms of leadership in the education system for the country to be able to cater for a democratic society. Amongst others, teachers became active creators and managers of the learning outcomes. In addition, teachers are regarded as agents of change and the driving force for productive teaching and learning. Literature describes how the management in schools has been redistributing authority and power so that a culture of teacher leadership in school communities can grow. More importantly, school improvement depends more on the active involvement of teacher leaders as it is realised that people in formal positions cannot do everything. In this line this study investigated the understanding of teachers and members of management of teacher leadership practice and it further identified the structural and cultural factors which enabled and inhibited this practice in a primary school. This study is a case study of a Primary school in a semi-urban area of Otjozondjupa Region, a central part of Namibia. This study was conducted in the interpretive paradigm and it is a qualitative case in nature, employing semi-structured interviews, observation and document analysis. Triangulation over the data revealed that respondents have an understanding of the concept and that all teachers are involved in leadership roles at school which are more strongly found in the classroom and through involvement with other teachers. Teacher leadership roles at the case study school also occur within the whole school with some limitations and also extend beyond the school. Grant’s (2008) model of teacher leadership was used to analyse the data. The study suggested some hindrances and supporting factors of teacher leadership. The findings suggested that teacher leadership is understood at the case study school and that they experienced factors that enabled and hindered this practice at different stages. Enabling factors included the school structure, further studies and workshops attended, while teacher leadership is impeded by teachers’ unwillingness to collaborate with others and the platoon system. The study recommends future large scale studies, including at secondary schools, so that a broader sense of teacher leadership may emerge.
- Full Text:
- Authors: Hanghuwo, Maria Nahambo
- Date: 2015
- Subjects: Democracy and education -- Study and teaching (Elementary) -- Namibia , Educational leadership , Teacher participation in administration
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2030 , http://hdl.handle.net/10962/d1017341
- Description: The education system in Namibia was shaped by the policies located within the framework of the apartheid ideology. Since it gained its independence in 1990, the government positioned education at the top of the national priorities. Thus, there has been a growing realisation of the importance of more democratic forms of leadership in the education system for the country to be able to cater for a democratic society. Amongst others, teachers became active creators and managers of the learning outcomes. In addition, teachers are regarded as agents of change and the driving force for productive teaching and learning. Literature describes how the management in schools has been redistributing authority and power so that a culture of teacher leadership in school communities can grow. More importantly, school improvement depends more on the active involvement of teacher leaders as it is realised that people in formal positions cannot do everything. In this line this study investigated the understanding of teachers and members of management of teacher leadership practice and it further identified the structural and cultural factors which enabled and inhibited this practice in a primary school. This study is a case study of a Primary school in a semi-urban area of Otjozondjupa Region, a central part of Namibia. This study was conducted in the interpretive paradigm and it is a qualitative case in nature, employing semi-structured interviews, observation and document analysis. Triangulation over the data revealed that respondents have an understanding of the concept and that all teachers are involved in leadership roles at school which are more strongly found in the classroom and through involvement with other teachers. Teacher leadership roles at the case study school also occur within the whole school with some limitations and also extend beyond the school. Grant’s (2008) model of teacher leadership was used to analyse the data. The study suggested some hindrances and supporting factors of teacher leadership. The findings suggested that teacher leadership is understood at the case study school and that they experienced factors that enabled and hindered this practice at different stages. Enabling factors included the school structure, further studies and workshops attended, while teacher leadership is impeded by teachers’ unwillingness to collaborate with others and the platoon system. The study recommends future large scale studies, including at secondary schools, so that a broader sense of teacher leadership may emerge.
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The identification and evaluation of key sustainable development indicators and the development of a conceptual decision-making model for capital investment within Gold Fields Limited (GFL)
- Authors: Jacobs, Phillip A H
- Date: 2010
- Subjects: Industrial management -- Environmental aspects -- South Africa -- Case studies Social responsibility of business -- South Africa -- Case studies Environmental protection -- South Africa -- Case studies Sustainable development -- South Africa -- Case studies Business ethics -- South Africa -- Case studies Industries -- Social aspects -- South Africa -- Case studies Industries -- Moral and ethical aspects -- South Africa -- Case studies Gold Fields Ltd -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:820 , http://hdl.handle.net/10962/d1008304
- Description: The current trends in sustainable development (SO) were examined in this study, which brought about the realisation that SO has become a business imperative. Mining, which is a highly impacting industry, is faced with the dilemma of implementing the principles of SO despite the realisation that its activities are severely limited by· the finite nature of the resource it is capitalising on. This reality, however, does not detract from the non-negotiable requirement for the industry to meet the increasing pressures to act responsibly towards the environment and the community in which it operates. Gold Fields has stepped up to the plate and has already taken several steps to achieve this end. These include the adoption of SO in its Vision, Values and strategies and the development and implementation of a SO framework to ensure the integration of the principles of SO into the business. Furthermore, Gold Fields has also entered into voluntary activities that further cement the commitment the company has towards so. These other initiatives include, inter alia, its International Council on Mining and Metals membership, UN Global Compact participation, becoming a signatory to the cyanide code, IS014001, and so on. This study focussed on several indicator categories and the identification of a set of supporting sustainable development indicators (SOls) for each, which included environmental, social, economic, technological, and ethics, legal and corporate governance (not in order of priority). These indicators were assessed by a carefully selected group of respondents whose collective wisdom and expertise were used to identify and weight supporting SOls for each of the indicator categories. These supporting SOls were in turn used to develop a model that is able to assist in the business's decision making processes when capital investment is being considered . A water treatment project that is currently being considered by Gold Fields was utilised to demonstrate how the decision making model can be applied to two different scenarios. The result clearly and successfully demonstrated that by proactively taking environmental, economic, social, technological, and ethics, legal and corporate governance considerations into account, a gold mining company is able to increase the level of SO of a capital investment project.
- Full Text:
- Authors: Jacobs, Phillip A H
- Date: 2010
- Subjects: Industrial management -- Environmental aspects -- South Africa -- Case studies Social responsibility of business -- South Africa -- Case studies Environmental protection -- South Africa -- Case studies Sustainable development -- South Africa -- Case studies Business ethics -- South Africa -- Case studies Industries -- Social aspects -- South Africa -- Case studies Industries -- Moral and ethical aspects -- South Africa -- Case studies Gold Fields Ltd -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:820 , http://hdl.handle.net/10962/d1008304
- Description: The current trends in sustainable development (SO) were examined in this study, which brought about the realisation that SO has become a business imperative. Mining, which is a highly impacting industry, is faced with the dilemma of implementing the principles of SO despite the realisation that its activities are severely limited by· the finite nature of the resource it is capitalising on. This reality, however, does not detract from the non-negotiable requirement for the industry to meet the increasing pressures to act responsibly towards the environment and the community in which it operates. Gold Fields has stepped up to the plate and has already taken several steps to achieve this end. These include the adoption of SO in its Vision, Values and strategies and the development and implementation of a SO framework to ensure the integration of the principles of SO into the business. Furthermore, Gold Fields has also entered into voluntary activities that further cement the commitment the company has towards so. These other initiatives include, inter alia, its International Council on Mining and Metals membership, UN Global Compact participation, becoming a signatory to the cyanide code, IS014001, and so on. This study focussed on several indicator categories and the identification of a set of supporting sustainable development indicators (SOls) for each, which included environmental, social, economic, technological, and ethics, legal and corporate governance (not in order of priority). These indicators were assessed by a carefully selected group of respondents whose collective wisdom and expertise were used to identify and weight supporting SOls for each of the indicator categories. These supporting SOls were in turn used to develop a model that is able to assist in the business's decision making processes when capital investment is being considered . A water treatment project that is currently being considered by Gold Fields was utilised to demonstrate how the decision making model can be applied to two different scenarios. The result clearly and successfully demonstrated that by proactively taking environmental, economic, social, technological, and ethics, legal and corporate governance considerations into account, a gold mining company is able to increase the level of SO of a capital investment project.
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The political economy of development aid: an investigation of three donor-funded HIV/AIDS programmes broadcast by Malawi television from 2004 to 2007
- Authors: Mulonya, Rodrick K A R
- Date: 2010
- Subjects: Economic assistance -- Malawi -- Management , Public service television programs -- Malawi , AIDS (Disease) and mass media -- Malawi , HIV infections -- Information services -- Malawi , Communication in public health -- Malawi , Economic assistance -- Social aspects -- Malawi , Malawi -- Social conditions , Mass media -- Social aspects -- Malawi , Mass media criticism -- Malawi
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3471 , http://hdl.handle.net/10962/d1002926
- Description: Development aid in most of the developing countries can sometimes compromise the principles of public service broadcasting (PSB). This may be true when reflected against the tension between donor financed programmes in Malawi and the mandate of Television Malawi (TVM). Although the donor intentions are noble, the strings attached to the funding are sometimes retrogressive to the role of PSBs. A case in point is how donors dictate terms on the HIV/Aids communication strategies at TVM. Producers receive money from donors with strings attached on how the money should be used and accounted for. If producers deviate they are sanctioned through withholding funding, shifting schedules and reducing the funding frequency. The donors also dictate who to interview on what subject, how to conduct capacity building. Some scholars have researched much on the impact of commercialisation of the media. This study is a departure from these traditional interferences; it interrogates the interest of philanthropy tendencies by international donors in the three chosen HIV/Aids programmes broadcast by TVM. The study investigates the extent of pressure exerted by donors on the producers of HIV/Aids programmes in Malawi. Thus, the study seeks to illicit specifics in the power relationship between the donor and the producer hence the study employs the political economy of development aid as applied to the public service broadcasting and communication for development. The study employed qualitative research methods and techniques (in-depth interviews, case study and document analysis). The study reveals how donor ideologies dominate the Aids messages-content output of the texts constructed. The study argues that cultural alienation of the Malawian audiences retards efforts of donors in combating HIV infection rate.
- Full Text:
- Authors: Mulonya, Rodrick K A R
- Date: 2010
- Subjects: Economic assistance -- Malawi -- Management , Public service television programs -- Malawi , AIDS (Disease) and mass media -- Malawi , HIV infections -- Information services -- Malawi , Communication in public health -- Malawi , Economic assistance -- Social aspects -- Malawi , Malawi -- Social conditions , Mass media -- Social aspects -- Malawi , Mass media criticism -- Malawi
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3471 , http://hdl.handle.net/10962/d1002926
- Description: Development aid in most of the developing countries can sometimes compromise the principles of public service broadcasting (PSB). This may be true when reflected against the tension between donor financed programmes in Malawi and the mandate of Television Malawi (TVM). Although the donor intentions are noble, the strings attached to the funding are sometimes retrogressive to the role of PSBs. A case in point is how donors dictate terms on the HIV/Aids communication strategies at TVM. Producers receive money from donors with strings attached on how the money should be used and accounted for. If producers deviate they are sanctioned through withholding funding, shifting schedules and reducing the funding frequency. The donors also dictate who to interview on what subject, how to conduct capacity building. Some scholars have researched much on the impact of commercialisation of the media. This study is a departure from these traditional interferences; it interrogates the interest of philanthropy tendencies by international donors in the three chosen HIV/Aids programmes broadcast by TVM. The study investigates the extent of pressure exerted by donors on the producers of HIV/Aids programmes in Malawi. Thus, the study seeks to illicit specifics in the power relationship between the donor and the producer hence the study employs the political economy of development aid as applied to the public service broadcasting and communication for development. The study employed qualitative research methods and techniques (in-depth interviews, case study and document analysis). The study reveals how donor ideologies dominate the Aids messages-content output of the texts constructed. The study argues that cultural alienation of the Malawian audiences retards efforts of donors in combating HIV infection rate.
- Full Text:
Reactions in the solid state
- Authors: Brown, Michael Ewart
- Date: 2006
- Subjects: Solid state chemistry , Thermal analysis , Chemistry, Analytic
- Language: English
- Type: Thesis , Doctoral , DSc
- Identifier: vital:4529 , http://hdl.handle.net/10962/d1015762
- Description: I have chosen the title for this thesis, "Reactions in the Solid State", for two reasons: Firstly, it is broad enough to cover all of my areas of research, which have been: • Effects of irradiation on solids (PhD topic) • Silver refining (while at the Chamber of Mines) • Kinetics of decomposition of solids (with Dr A.K. Galwey and various others) • Techniques of thermal analysis • Pyrotechnic delay systems (with support from AECI Explosives) • Thermal and photostability of drugs (with Prof B.D. Glass) and, secondly, it was the title of the very successful book co-authored by Drs Andrew Galwey, David Dollimore and me. A large part of my research has been involved in the writing and editing of books, so these are covered in a separate commentary, while commentary on the more than 100 papers to which I have contributed forms the main part of this compilation. It is hoped that the electronic format will enable ready access of to all aspects of my research, including electronic versions of the original papers. The reader will need a copy of Adobe Acrobat Reader to access these.
- Full Text:
- Authors: Brown, Michael Ewart
- Date: 2006
- Subjects: Solid state chemistry , Thermal analysis , Chemistry, Analytic
- Language: English
- Type: Thesis , Doctoral , DSc
- Identifier: vital:4529 , http://hdl.handle.net/10962/d1015762
- Description: I have chosen the title for this thesis, "Reactions in the Solid State", for two reasons: Firstly, it is broad enough to cover all of my areas of research, which have been: • Effects of irradiation on solids (PhD topic) • Silver refining (while at the Chamber of Mines) • Kinetics of decomposition of solids (with Dr A.K. Galwey and various others) • Techniques of thermal analysis • Pyrotechnic delay systems (with support from AECI Explosives) • Thermal and photostability of drugs (with Prof B.D. Glass) and, secondly, it was the title of the very successful book co-authored by Drs Andrew Galwey, David Dollimore and me. A large part of my research has been involved in the writing and editing of books, so these are covered in a separate commentary, while commentary on the more than 100 papers to which I have contributed forms the main part of this compilation. It is hoped that the electronic format will enable ready access of to all aspects of my research, including electronic versions of the original papers. The reader will need a copy of Adobe Acrobat Reader to access these.
- Full Text:
The impact of smart cards on South African rural pensioners' lives
- Authors: Nyoka, Zanele
- Date: 2004
- Subjects: Old age pensioners -- South Africa -- Management Smart cards South African Post Office
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:818 , http://hdl.handle.net/10962/d1008052
- Description: E-commerce technologies have many possible applications both in commercial and non-commercial operations. The development and implementation of these applications is on the increase especially by government and its agencies, for the delivery of services. Specific to this study is the distribution of old age pension benefits to recipients that reside in the rural areas of South Africa. Of importance to this study are the factors that promote and impinge on the development, implementation and acceptance of these applications. A specific project, the Pension Biometric Project was implemented by the South African Post Office in line with the government's initiatives of improving service delivery, and in response to the encroaching digital economy. The research problem is to investigate the pensioners' perception and their experience of three areas of this project, its implementation, its acceptance and its uses and impact. The research was conducted in the constructivist paradigm, using the case study research method. Three data collection methods were used, i.e. a document study of SAPO project documentation, on-site observations and interviews with pensioners. It was found that despite problems in implementation, the pensioners were accepting of the new system, although they were ignorant of the functionalities of the smart card. Consequently, few pensioners were making use of the banking facilities of the card, or had changed their economic behaviour. The study has also found that two themes are overriding all findings of the study. These two themes are ignorance and dignity. Ignorance has had a causal effect on adoption of the smart cards and dignity has been found to be a result of the project. The overriding implication of this study is that pensioners' ignorance around issues of service delivery by government and its agencies needs to be eradicated, otherwise there is no reliable way of measuring efforts against actual delivery. Also, the fact that dignity has emerged as an overriding theme needs to be deliberately strengthened, and maybe even driven as a specified objective of the Pension Biometric Project. Recommendations in this regard are provided as well as ideas for further research.
- Full Text:
- Authors: Nyoka, Zanele
- Date: 2004
- Subjects: Old age pensioners -- South Africa -- Management Smart cards South African Post Office
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:818 , http://hdl.handle.net/10962/d1008052
- Description: E-commerce technologies have many possible applications both in commercial and non-commercial operations. The development and implementation of these applications is on the increase especially by government and its agencies, for the delivery of services. Specific to this study is the distribution of old age pension benefits to recipients that reside in the rural areas of South Africa. Of importance to this study are the factors that promote and impinge on the development, implementation and acceptance of these applications. A specific project, the Pension Biometric Project was implemented by the South African Post Office in line with the government's initiatives of improving service delivery, and in response to the encroaching digital economy. The research problem is to investigate the pensioners' perception and their experience of three areas of this project, its implementation, its acceptance and its uses and impact. The research was conducted in the constructivist paradigm, using the case study research method. Three data collection methods were used, i.e. a document study of SAPO project documentation, on-site observations and interviews with pensioners. It was found that despite problems in implementation, the pensioners were accepting of the new system, although they were ignorant of the functionalities of the smart card. Consequently, few pensioners were making use of the banking facilities of the card, or had changed their economic behaviour. The study has also found that two themes are overriding all findings of the study. These two themes are ignorance and dignity. Ignorance has had a causal effect on adoption of the smart cards and dignity has been found to be a result of the project. The overriding implication of this study is that pensioners' ignorance around issues of service delivery by government and its agencies needs to be eradicated, otherwise there is no reliable way of measuring efforts against actual delivery. Also, the fact that dignity has emerged as an overriding theme needs to be deliberately strengthened, and maybe even driven as a specified objective of the Pension Biometric Project. Recommendations in this regard are provided as well as ideas for further research.
- Full Text:
People-centred development in practice: the case of the Zikhova-Ngqinisa Sidibene Woodlot Trust Project
- Authors: Pona, Faith Zolisa
- Date: 2003
- Subjects: Zikhova-Ngqinisa Sidibene Woodlot Trust Project , Rural development -- South Africa -- Eastern Cape , Rural development projects -- South Africa -- Eastern Cape -- Citizen participation , Woodlots -- South Africa -- Eastern Cape , Economic development projects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3356 , http://hdl.handle.net/10962/d1007610 , Zikhova-Ngqinisa Sidibene Woodlot Trust Project , Rural development -- South Africa -- Eastern Cape , Rural development projects -- South Africa -- Eastern Cape -- Citizen participation , Woodlots -- South Africa -- Eastern Cape , Economic development projects -- South Africa -- Eastern Cape
- Description: This study addresses the question of people-centred development as a transformative aspect of the new South African development arena. The concept is defined as the involvement and active participation of people in the decision-making, evaluation and implementation of the development processes, It is one of the forms of democratisation which involves the decentralisaton of authority to the lower tiers of government. This study provides an analysis of the efficacy, relevance, advantages and disadvantages of people-centred development in the South African context. The Zikhoya-Ngqinisa Woodlot Trust Project was chosen as a case study, The reason was that through the process of devolution of the Department of Forestry and Water Affairs (DWAF), which involved the handing over of the management and financial resources of the small woodlots to the communities for their own benefit, the two villages, Zikhova and Ngqinisa, were given the Zikhova woodlot. The devolution of DWAF is one of the various forms of decentralisation that has given more autonomy to the lower tiers of government in the sense that the communities now have to satisfy their own needs. The main focus of the study was to identify and analyse constraints on the implementation of people-centred development specific to the Zikhova-Ngqinisa Woodlot Trust Project. Other interrelated aspects of people-centred development such as sustainability, community involvement and benefits of the project were also investigated and analysed. , KMBT_363
- Full Text:
- Authors: Pona, Faith Zolisa
- Date: 2003
- Subjects: Zikhova-Ngqinisa Sidibene Woodlot Trust Project , Rural development -- South Africa -- Eastern Cape , Rural development projects -- South Africa -- Eastern Cape -- Citizen participation , Woodlots -- South Africa -- Eastern Cape , Economic development projects -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3356 , http://hdl.handle.net/10962/d1007610 , Zikhova-Ngqinisa Sidibene Woodlot Trust Project , Rural development -- South Africa -- Eastern Cape , Rural development projects -- South Africa -- Eastern Cape -- Citizen participation , Woodlots -- South Africa -- Eastern Cape , Economic development projects -- South Africa -- Eastern Cape
- Description: This study addresses the question of people-centred development as a transformative aspect of the new South African development arena. The concept is defined as the involvement and active participation of people in the decision-making, evaluation and implementation of the development processes, It is one of the forms of democratisation which involves the decentralisaton of authority to the lower tiers of government. This study provides an analysis of the efficacy, relevance, advantages and disadvantages of people-centred development in the South African context. The Zikhoya-Ngqinisa Woodlot Trust Project was chosen as a case study, The reason was that through the process of devolution of the Department of Forestry and Water Affairs (DWAF), which involved the handing over of the management and financial resources of the small woodlots to the communities for their own benefit, the two villages, Zikhova and Ngqinisa, were given the Zikhova woodlot. The devolution of DWAF is one of the various forms of decentralisation that has given more autonomy to the lower tiers of government in the sense that the communities now have to satisfy their own needs. The main focus of the study was to identify and analyse constraints on the implementation of people-centred development specific to the Zikhova-Ngqinisa Woodlot Trust Project. Other interrelated aspects of people-centred development such as sustainability, community involvement and benefits of the project were also investigated and analysed. , KMBT_363
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A critical investigation into the managerial implications of inclusive education
- Authors: Cloete, Sanet
- Date: 2002
- Subjects: School management and organization -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1477 , http://hdl.handle.net/10962/d1003358
- Description: Special needs education has always provided special challenges to school administrators, policy makers and teachers. The world-wide move towards inclusive education as an alternative to exclusive education or casual mainstreaming has resulted in significant developments in Namibia in the past decade. Global educational reforms have focused on education for all as well as inclusive education and Namibia is signatory to several conventions and declarations in this regard. Research in this field has largely focused on the role of the inclusive teacher, and of course the special needs of the learners. Little or no attention has been paid to possible managerial and organisational challenges which accompany the move to inclusive education. This thesis seeks to critically investigate the managerial implications of inclusive education. The focal point of this research is to gain a clear understanding of the managerial implications in an inclusive school for learners with visual impairment, chiefly through an exploration of the experiences of management members of the inclusive process. The research is located within a qualitative research paradigm, which is subsumed by a phenomenological model. The data gathered through in-depth interviews include many anecdotal accounts that provide insight into the ways respondents reacted to experiences at the inclusive school. The main findings of the research are highlighted and discussed. Recommendations arising from a critical analysis of these main findings are presented.
- Full Text:
- Authors: Cloete, Sanet
- Date: 2002
- Subjects: School management and organization -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1477 , http://hdl.handle.net/10962/d1003358
- Description: Special needs education has always provided special challenges to school administrators, policy makers and teachers. The world-wide move towards inclusive education as an alternative to exclusive education or casual mainstreaming has resulted in significant developments in Namibia in the past decade. Global educational reforms have focused on education for all as well as inclusive education and Namibia is signatory to several conventions and declarations in this regard. Research in this field has largely focused on the role of the inclusive teacher, and of course the special needs of the learners. Little or no attention has been paid to possible managerial and organisational challenges which accompany the move to inclusive education. This thesis seeks to critically investigate the managerial implications of inclusive education. The focal point of this research is to gain a clear understanding of the managerial implications in an inclusive school for learners with visual impairment, chiefly through an exploration of the experiences of management members of the inclusive process. The research is located within a qualitative research paradigm, which is subsumed by a phenomenological model. The data gathered through in-depth interviews include many anecdotal accounts that provide insight into the ways respondents reacted to experiences at the inclusive school. The main findings of the research are highlighted and discussed. Recommendations arising from a critical analysis of these main findings are presented.
- Full Text:
Cuba's revolutionist and anti-imperialist foreign policy in Southern Africa: the case of Angola and Namibia
- Authors: Othieno, Timothy
- Date: 2000
- Subjects: Cuba -- Foreign Relations -- Africa, Southern , Cuba -- Dependency on foreign countries -- History , Cuba -- Foreign relations -- Angola , Cuba -- Foreign relations -- Namibia , Cuba -- Politics and government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2819 , http://hdl.handle.net/10962/d1003029 , Cuba -- Foreign Relations -- Africa, Southern , Cuba -- Dependency on foreign countries -- History , Cuba -- Foreign relations -- Angola , Cuba -- Foreign relations -- Namibia , Cuba -- Politics and government
- Description: This study examines Cuba’s role in the two southern African countries of Angola and Namibia during the Cold War period. It argues that Cuba’s ideological motivations have been embodied in the mutually reinforcing concepts of proletarian internationalism and anti-imperialism. These conceptual perspectives constitute some of the central variables that influence Cuba’s foreign policy behaviour in international relations. It is within this context that one can understand Cuba’s involvement in Southern Africa. This study also attempts to explain that Cuban foreign policy towards Africa was based on two complementary and contextual objectives namely, promoting nationalism at home and nurturing revolutionary Marxist-Leninist governments, as well as supporting anti-colonial and anti-imperialist movements abroad. For the purpose of achieving these foreign policy objectives, Cuba not only engaged in state-to-state relations with Angola and Namibia; but had cordial relations with the rest of the continent and in particular Southern Africa, which also became a direct military testing ground for Cuba’s commitment to an anti-colonial and anti-imperialist revolutionary stance. Furthermore, the thesis shows that Cuba’s relentless hatred of imperialism is rooted in its historical relationship with the United States because from the turn of the century till 1958, the Americans interfered in Cuba’s internal affairs by supporting corrupt administrations and exploited the country. These practices by the United States laid the foundation for Cuba’s anti-colonialism and antiimperialism abroad. Ultimately, this thesis shows that Cuban involvement in Angola and Namibia can be conceptualised within these contexts (anti-imperialism, anti-colonialism, proletarian internationalism and revolutionary Marxism-Leninism). The role of Cuban nationalism in the realisation of these objectives and ideals, as well as its role in perpetuating and consolidating her foreign policy is assessed in this study. This nationalism and ideals of internationalism constitutes the central idea in the Cuban revolution. Finally, this thesis asserts that Cuban motives for getting involved in the politics of Southern Africa were not motivated by economic or imperialistic reasons. Rather, the historical similarity and colonial experiences between Africa and Cuba were some of the central causal factors.
- Full Text:
- Authors: Othieno, Timothy
- Date: 2000
- Subjects: Cuba -- Foreign Relations -- Africa, Southern , Cuba -- Dependency on foreign countries -- History , Cuba -- Foreign relations -- Angola , Cuba -- Foreign relations -- Namibia , Cuba -- Politics and government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2819 , http://hdl.handle.net/10962/d1003029 , Cuba -- Foreign Relations -- Africa, Southern , Cuba -- Dependency on foreign countries -- History , Cuba -- Foreign relations -- Angola , Cuba -- Foreign relations -- Namibia , Cuba -- Politics and government
- Description: This study examines Cuba’s role in the two southern African countries of Angola and Namibia during the Cold War period. It argues that Cuba’s ideological motivations have been embodied in the mutually reinforcing concepts of proletarian internationalism and anti-imperialism. These conceptual perspectives constitute some of the central variables that influence Cuba’s foreign policy behaviour in international relations. It is within this context that one can understand Cuba’s involvement in Southern Africa. This study also attempts to explain that Cuban foreign policy towards Africa was based on two complementary and contextual objectives namely, promoting nationalism at home and nurturing revolutionary Marxist-Leninist governments, as well as supporting anti-colonial and anti-imperialist movements abroad. For the purpose of achieving these foreign policy objectives, Cuba not only engaged in state-to-state relations with Angola and Namibia; but had cordial relations with the rest of the continent and in particular Southern Africa, which also became a direct military testing ground for Cuba’s commitment to an anti-colonial and anti-imperialist revolutionary stance. Furthermore, the thesis shows that Cuba’s relentless hatred of imperialism is rooted in its historical relationship with the United States because from the turn of the century till 1958, the Americans interfered in Cuba’s internal affairs by supporting corrupt administrations and exploited the country. These practices by the United States laid the foundation for Cuba’s anti-colonialism and antiimperialism abroad. Ultimately, this thesis shows that Cuban involvement in Angola and Namibia can be conceptualised within these contexts (anti-imperialism, anti-colonialism, proletarian internationalism and revolutionary Marxism-Leninism). The role of Cuban nationalism in the realisation of these objectives and ideals, as well as its role in perpetuating and consolidating her foreign policy is assessed in this study. This nationalism and ideals of internationalism constitutes the central idea in the Cuban revolution. Finally, this thesis asserts that Cuban motives for getting involved in the politics of Southern Africa were not motivated by economic or imperialistic reasons. Rather, the historical similarity and colonial experiences between Africa and Cuba were some of the central causal factors.
- Full Text:
Paul and Barnabas in Lystra (Acts 14:8-20): the contextualization of the Gospel in a Graeco-Roman city
- Authors: Germiquet, Edouard Ariste
- Date: 1992
- Subjects: Bible. Acts -- Criticism, interpretation, etc.
- Language: English
- Type: Thesis , Masters , MTh
- Identifier: vital:1306 , http://hdl.handle.net/10962/d1018213
- Description: This thesis will investigate the extensive Graeco-Roman characteristics of the Lystra speech and in so doing convey some clarity in the otherwise widely differing opinions held about it. This will be achieved by showing that Lystra was a Hellenistic city of some importance with a varied population. It will be argued that the initial reaction of the Lystrians to the miraculous healing of the cripple is to be understood as representing typical Graeco-Roman notions. This will include Luke's use of a legend which not only adds local colouring to the narrative but also introduces Graeco-Roman themes such as the blurring of the distinction between humans and gods and the custom of sacrifice. This contextualization immediately portrays the Graeco-Roman nature of the Lystrians' behaviour and attitudes. In addition to these themes it will be argued that the Lystrians are shown to being reliant on secondary notions of God, which when exposed to the proclamation of the apostles will prove to be inadequate. It will also be argued that the speech of the apostles is structured in a typically Graeco-Roman rhetorical form, where the errors are first exposed before the truth is presented. In conjunction with this structure it will be argued that the philosophical concept of which Dibelius has shown to be clearly presupposed in the Areopagus speech, is not only present in the Lystra speech but forms the philosophical basis on which it is structured. This concept explains the insistence by the apostles that they are human and that God has no need of such worthless things as sacrifices. It also explains the presentation of God's activity in creation and providence as an antithesis to a god who is in need. The Graeco-Roman aspects are brought to a close with the discussion of idea that an awareness of God does not depend on secondary notions acquired from legends or customs but that the truth is grasped through a process of reflection on creation and providence. This is an important notion in the speech for it exposes the Lystrians as being in need of a reorientation of their beliefs in God, away from those which are secondary to those which are primary and compatible with the truth.
- Full Text:
- Authors: Germiquet, Edouard Ariste
- Date: 1992
- Subjects: Bible. Acts -- Criticism, interpretation, etc.
- Language: English
- Type: Thesis , Masters , MTh
- Identifier: vital:1306 , http://hdl.handle.net/10962/d1018213
- Description: This thesis will investigate the extensive Graeco-Roman characteristics of the Lystra speech and in so doing convey some clarity in the otherwise widely differing opinions held about it. This will be achieved by showing that Lystra was a Hellenistic city of some importance with a varied population. It will be argued that the initial reaction of the Lystrians to the miraculous healing of the cripple is to be understood as representing typical Graeco-Roman notions. This will include Luke's use of a legend which not only adds local colouring to the narrative but also introduces Graeco-Roman themes such as the blurring of the distinction between humans and gods and the custom of sacrifice. This contextualization immediately portrays the Graeco-Roman nature of the Lystrians' behaviour and attitudes. In addition to these themes it will be argued that the Lystrians are shown to being reliant on secondary notions of God, which when exposed to the proclamation of the apostles will prove to be inadequate. It will also be argued that the speech of the apostles is structured in a typically Graeco-Roman rhetorical form, where the errors are first exposed before the truth is presented. In conjunction with this structure it will be argued that the philosophical concept of which Dibelius has shown to be clearly presupposed in the Areopagus speech, is not only present in the Lystra speech but forms the philosophical basis on which it is structured. This concept explains the insistence by the apostles that they are human and that God has no need of such worthless things as sacrifices. It also explains the presentation of God's activity in creation and providence as an antithesis to a god who is in need. The Graeco-Roman aspects are brought to a close with the discussion of idea that an awareness of God does not depend on secondary notions acquired from legends or customs but that the truth is grasped through a process of reflection on creation and providence. This is an important notion in the speech for it exposes the Lystrians as being in need of a reorientation of their beliefs in God, away from those which are secondary to those which are primary and compatible with the truth.
- Full Text:
The playing characteristics of American trombones and German-system bassoons
- Authors: Galloway, David John
- Date: 1985
- Subjects: Trombone Bassoon
- Language: English
- Type: Thesis , Masters , MMus
- Identifier: vital:2661 , http://hdl.handle.net/10962/d1004508
- Description: Preface: South Africa, a country renowned for its mineral wealth has, perhaps manufacturing paradoxically, no musical wind instrument industry of its own as yet. Thus performers, educators and students alike have either to travel to Europe or America to select an instrument, or to import an expensive instrument that may be both unseen and untried, as very few musical instrument dealers are prepared to outlay capital on stock which appeals to a decided minority of their potential customers. Alternately, a purchase of a particular make or model can be made on the basis of a hearsay opinion; at best, the opportunity for first-hand assessment is minimal. It is the trombone of U. S.A. manufacture and the German bassoon which represent the current state of their respective manufacturing arts, and the yardsticks by which their many imitator's efforts are measured. One of the main aims of this Thesis is to describe in objective terms what has been experienced subjectively over the years of involvement with these instruments -- arguably a task similar to that of the art critic, but operating within more positively defined parameters namely, what works for the student and professional. , and what doesn't. The candidate claims credit for introducing the large-bore Bb/F trombone to South Africa in 1961, following with the introduction of the ·first double-valve bass trombone in 1965, and the first in 1979. The first Schreiber bassoons The advantages and trombone and other bassoon and other such instrument with in-line rotors of the new 5000 series larger-bore was likewise introduced in 1981. pitfalls of " doubling" between the wind instruments , and between the winds, are disc ussed at length in the final section of the Thesis.
- Full Text:
- Authors: Galloway, David John
- Date: 1985
- Subjects: Trombone Bassoon
- Language: English
- Type: Thesis , Masters , MMus
- Identifier: vital:2661 , http://hdl.handle.net/10962/d1004508
- Description: Preface: South Africa, a country renowned for its mineral wealth has, perhaps manufacturing paradoxically, no musical wind instrument industry of its own as yet. Thus performers, educators and students alike have either to travel to Europe or America to select an instrument, or to import an expensive instrument that may be both unseen and untried, as very few musical instrument dealers are prepared to outlay capital on stock which appeals to a decided minority of their potential customers. Alternately, a purchase of a particular make or model can be made on the basis of a hearsay opinion; at best, the opportunity for first-hand assessment is minimal. It is the trombone of U. S.A. manufacture and the German bassoon which represent the current state of their respective manufacturing arts, and the yardsticks by which their many imitator's efforts are measured. One of the main aims of this Thesis is to describe in objective terms what has been experienced subjectively over the years of involvement with these instruments -- arguably a task similar to that of the art critic, but operating within more positively defined parameters namely, what works for the student and professional. , and what doesn't. The candidate claims credit for introducing the large-bore Bb/F trombone to South Africa in 1961, following with the introduction of the ·first double-valve bass trombone in 1965, and the first in 1979. The first Schreiber bassoons The advantages and trombone and other bassoon and other such instrument with in-line rotors of the new 5000 series larger-bore was likewise introduced in 1981. pitfalls of " doubling" between the wind instruments , and between the winds, are disc ussed at length in the final section of the Thesis.
- Full Text:
Geology and ore reserve estimation of the Witwatersrand-type gold deposits with specific reference to the Welkom Goldfield
- Authors: Ainslie, L C
- Date: 1981
- Subjects: Mines and mineral resources -- Statistical methods Mine valuation -- Statistical methods Gold ores -- Geology Witwatersrand Basin (South Africa) Ores -- Sampling and estimation -- Statistical methods
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4911 , http://hdl.handle.net/10962/d1001571
- Full Text:
- Authors: Ainslie, L C
- Date: 1981
- Subjects: Mines and mineral resources -- Statistical methods Mine valuation -- Statistical methods Gold ores -- Geology Witwatersrand Basin (South Africa) Ores -- Sampling and estimation -- Statistical methods
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4911 , http://hdl.handle.net/10962/d1001571
- Full Text:
First H F Doppler soundings of the ionosphere at SANAE
- Authors: De Kock, Errol James
- Date: 1980
- Subjects: Ionosphere
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5500 , http://hdl.handle.net/10962/d1006869 , Ionosphere
- Full Text:
- Authors: De Kock, Errol James
- Date: 1980
- Subjects: Ionosphere
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5500 , http://hdl.handle.net/10962/d1006869 , Ionosphere
- Full Text:
A study of some aspects of the poor white problem in South Africa
- Authors: Lewis, Robert Alexander
- Date: 1979
- Subjects: Poor white problem , Afrikaners -- Economic conditions , Poor -- South Africa , South Africa -- Economic conditions , South Africa -- Social conditions
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2524 , http://hdl.handle.net/10962/d1001853
- Description: The first instance of the poor white problem being dramatically brought to the attention of white South Africa was in 1893 when Rev. Andrew Murray issued an open letter on the subject which resulted in the convening of the first of many Dutch Reformed Church conferences on the problem (Introduction, p. 1).
- Full Text:
- Authors: Lewis, Robert Alexander
- Date: 1979
- Subjects: Poor white problem , Afrikaners -- Economic conditions , Poor -- South Africa , South Africa -- Economic conditions , South Africa -- Social conditions
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2524 , http://hdl.handle.net/10962/d1001853
- Description: The first instance of the poor white problem being dramatically brought to the attention of white South Africa was in 1893 when Rev. Andrew Murray issued an open letter on the subject which resulted in the convening of the first of many Dutch Reformed Church conferences on the problem (Introduction, p. 1).
- Full Text:
Physico-chemical and substructural studies on Nudaurelia capensis β virus
- Authors: Struthers, J Keith
- Date: 1974
- Subjects: Imbrasia cytherea , Insects -- Viruses , RNA viruses , DNA
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4075 , http://hdl.handle.net/10962/d1007327 , Imbrasia cytherea , Insects -- Viruses , RNA viruses , DNA
- Description: From Introduction: The pine emperor moth, Nudaurelia cytherea capensis Stoll is an insect which, during the larval stage, causes extensive defoliation of the pine tree, Pinus radiata in the Cape province. These insects are susceptible to a virus disease, which on occasions causes large scale mortality. Five nonoccluded viruses have been shown to infect the pine emperor moth, and of these, one found in the greatest concentration, Nudaurelia capensis β virus (NβV) has been characterised to the greatest extent. This virus has been shown to contain RNA, to be isometric with a diameter of 36 mm, and to have a molecular weight of 16 million. The virus occurs in all stages of the insect's development, and by fluorescent antibody staining has been shown to develop in the cytoplasm of the host's cells. There have in recent years been a number of reports describing nonoccluded RNA viruses which appear to be similar to NβV. These are the viruses isolated from the moths Gonometa podocarpi and Antheraea eucalypti, and the one from the citrus red mite, Panonychus citri. These viruses have not been as extensively characterised as NβV, so the extent of the similarity between them and NβV is not known. However it would appear as if their discovery collectively heralds the emergence of a distinct new grouping within the nonoccluded RNA viruses of insects. This work reports the isolation and further characterisation of N. capensis β virus, its protein and nucleic acid.
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- Authors: Struthers, J Keith
- Date: 1974
- Subjects: Imbrasia cytherea , Insects -- Viruses , RNA viruses , DNA
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4075 , http://hdl.handle.net/10962/d1007327 , Imbrasia cytherea , Insects -- Viruses , RNA viruses , DNA
- Description: From Introduction: The pine emperor moth, Nudaurelia cytherea capensis Stoll is an insect which, during the larval stage, causes extensive defoliation of the pine tree, Pinus radiata in the Cape province. These insects are susceptible to a virus disease, which on occasions causes large scale mortality. Five nonoccluded viruses have been shown to infect the pine emperor moth, and of these, one found in the greatest concentration, Nudaurelia capensis β virus (NβV) has been characterised to the greatest extent. This virus has been shown to contain RNA, to be isometric with a diameter of 36 mm, and to have a molecular weight of 16 million. The virus occurs in all stages of the insect's development, and by fluorescent antibody staining has been shown to develop in the cytoplasm of the host's cells. There have in recent years been a number of reports describing nonoccluded RNA viruses which appear to be similar to NβV. These are the viruses isolated from the moths Gonometa podocarpi and Antheraea eucalypti, and the one from the citrus red mite, Panonychus citri. These viruses have not been as extensively characterised as NβV, so the extent of the similarity between them and NβV is not known. However it would appear as if their discovery collectively heralds the emergence of a distinct new grouping within the nonoccluded RNA viruses of insects. This work reports the isolation and further characterisation of N. capensis β virus, its protein and nucleic acid.
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The salinity tolerance of some Eastern Province fish in relation to their known distribution
- Authors: Hofmeyr, Hendrik Petrus
- Date: 1966
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:21165 , http://hdl.handle.net/10962/6684
- Description: The tolerances to sea water, sodium chloride and sodium sulphate of various cichlid, cyprinid and anabantid species which occur naturally in or near the Eastern Province region of Southern Africa, were determined, and correlated with their distribution ranges. Of the nine freshwater species tested, only Tilapia mossambica is able to disperse through the sea and is therefore the only member of the secondary division (Myers 1937) present in this region. The remaining species are possibly all limited to the use of freshwater links for dispersal between river systems. Death of fish in sea water and in sodium chloride is chiefly due to loss of osmotic control, but in solutions of sodium sulphate a pronounced toxic effect is responsible for death. In all the solutions used, an inverse relation between survival time and concentration is present. No evidence of any cells specialised for salt excretion was found in the gills of fish exposed to various salt concentrations.
- Full Text:
- Authors: Hofmeyr, Hendrik Petrus
- Date: 1966
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:21165 , http://hdl.handle.net/10962/6684
- Description: The tolerances to sea water, sodium chloride and sodium sulphate of various cichlid, cyprinid and anabantid species which occur naturally in or near the Eastern Province region of Southern Africa, were determined, and correlated with their distribution ranges. Of the nine freshwater species tested, only Tilapia mossambica is able to disperse through the sea and is therefore the only member of the secondary division (Myers 1937) present in this region. The remaining species are possibly all limited to the use of freshwater links for dispersal between river systems. Death of fish in sea water and in sodium chloride is chiefly due to loss of osmotic control, but in solutions of sodium sulphate a pronounced toxic effect is responsible for death. In all the solutions used, an inverse relation between survival time and concentration is present. No evidence of any cells specialised for salt excretion was found in the gills of fish exposed to various salt concentrations.
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