Combined in silico approaches towards the identification of novel malarial cysteine protease inhibitors
- Authors: Musyoka, Thommas Mutemi
- Date: 2017
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/4488 , vital:20679
- Description: Malaria an infectious disease caused by a group of parasitic organisms of the Plasmodium genus remains a severe public health problem in Africa, South America and parts of Asia. The leading causes for the persistence of malaria are the emergence of drug resistance to common antimalarial drugs, lack of effective vaccines and the inadequate control of mosquito vectors. Worryingly, accumulating evidence shows that the parasite has developed resistant to the current first-line treatment based on artemisinin. Hence, the identification and characterization of novel drug targets and drugs with unique mode of action remains an urgent priority. The successful sequencing and assembly of genomes from several Plasmodium species has opened an opportune window for the identification of new drug targets. Cysteine proteases are one of the major drug targets to be identified so far. The use of cysteine protease inhibitors coupled with gene manipulation studies has defined specific and putative roles of cysteine proteases which include hemoglobin degradation, erythrocyte rupture, immune evasion and erythrocyte invasion, steps which are central for the completion of the Plasmodium parasite life cycle. In an aim to discover potential novel antimalarials, this thesis focussed on falcipains (FPs), a group of four papain-like cysteine proteases from Plasmodium falciparum. Two of these enzymes, FP-2 and FP-3 are the major hemoglobinases and have been validated as drug targets. For the successful elimination of malaria, drugs must be safe and target both human and wild Plasmodium infective forms. Thus, an incipient aim was to identify protein homologs of these two proteases from other Plasmodium species and the host (human). From BLASTP analysis, up to 16 FP-2 and FP-3 homologs were identified (13 plasmodial proteases and 3 human cathepsins). Using in silico characterization approaches, the intra and inter group sequence, structural, phylogenetic and physicochemical differences were determined. To extend previous work (MSc student) involving docking studies on the identified proteins using known FP-2 and FP-3 inhibitors, a South African natural compound and its ZINC analogs, molecular dynamics and binding free energy studies were performed to determine the stabilities and quantification of the strength of interactions between the different protein-ligand complexes. From the results, key structural elements that regulate the binding and selectivity of non-peptidic compounds onto the different proteins were deciphered. Interaction fingerprints and energy decomposition analysis identified key residues and energetic terms that are central for effective ligand binding. This research presents novel insight essential for the structure-based molecular drug design of more potent antimalarial drugs.
- Full Text:
- Authors: Musyoka, Thommas Mutemi
- Date: 2017
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/4488 , vital:20679
- Description: Malaria an infectious disease caused by a group of parasitic organisms of the Plasmodium genus remains a severe public health problem in Africa, South America and parts of Asia. The leading causes for the persistence of malaria are the emergence of drug resistance to common antimalarial drugs, lack of effective vaccines and the inadequate control of mosquito vectors. Worryingly, accumulating evidence shows that the parasite has developed resistant to the current first-line treatment based on artemisinin. Hence, the identification and characterization of novel drug targets and drugs with unique mode of action remains an urgent priority. The successful sequencing and assembly of genomes from several Plasmodium species has opened an opportune window for the identification of new drug targets. Cysteine proteases are one of the major drug targets to be identified so far. The use of cysteine protease inhibitors coupled with gene manipulation studies has defined specific and putative roles of cysteine proteases which include hemoglobin degradation, erythrocyte rupture, immune evasion and erythrocyte invasion, steps which are central for the completion of the Plasmodium parasite life cycle. In an aim to discover potential novel antimalarials, this thesis focussed on falcipains (FPs), a group of four papain-like cysteine proteases from Plasmodium falciparum. Two of these enzymes, FP-2 and FP-3 are the major hemoglobinases and have been validated as drug targets. For the successful elimination of malaria, drugs must be safe and target both human and wild Plasmodium infective forms. Thus, an incipient aim was to identify protein homologs of these two proteases from other Plasmodium species and the host (human). From BLASTP analysis, up to 16 FP-2 and FP-3 homologs were identified (13 plasmodial proteases and 3 human cathepsins). Using in silico characterization approaches, the intra and inter group sequence, structural, phylogenetic and physicochemical differences were determined. To extend previous work (MSc student) involving docking studies on the identified proteins using known FP-2 and FP-3 inhibitors, a South African natural compound and its ZINC analogs, molecular dynamics and binding free energy studies were performed to determine the stabilities and quantification of the strength of interactions between the different protein-ligand complexes. From the results, key structural elements that regulate the binding and selectivity of non-peptidic compounds onto the different proteins were deciphered. Interaction fingerprints and energy decomposition analysis identified key residues and energetic terms that are central for effective ligand binding. This research presents novel insight essential for the structure-based molecular drug design of more potent antimalarial drugs.
- Full Text:
Investigating how Grade 10 Physical Science teachers help learners to make sense of concepts of electromagnetism using easily accessible materials in under-resourced schools
- Authors: Samuel, Paulo
- Date: 2017
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/8143 , vital:21359
- Description: This study sought to explore teachers’ perceptions and experiences of using easily accessible materials and how they might collaboratively develop learning and teaching support materials using easily accessible materials. The study explored three aspects. Firstly, the views, experiences and factors which influence grade 10 Physical Science teachers’ perceptions and experiences of teaching the topic of electromagnetism. Secondly, to find out what teachers can do to improve teaching and learning of electromagnetism in grade 10 Physical Science using easily accessible materials. Thirdly, to look at what enables or constrains grade 10 Physical Science teachers in under-resourced schools when dealing with electromagnetism, from using easily accessible materials. A qualitative method approach was adopted, underpinned by an interpretive paradigm but using some quantitative methods as well. Within the interpretive paradigm a case study approach was used. The study was carried out in Swakopmund and Gobabis education circuits of the Erongo and Omaheke Regions respectively. Data were collected using questionnaires, lesson observations and stimulated-recall interviews. The data obtained were validated in two ways, firstly, by triangulation from different data gathering techniques, and secondly, validation was done by member checking of the transcripts. To make meaning from the data generated, Vygotsky’s (1978) socio-cultural theory was used as a lens to analyse the data. The quantitative data generated were presented in figures, tables; whereas the qualitative data were coded inductively into descriptive texts to make meaning. It was found that teachers’s perceptions and experiences are that the topic of electromagnetism is quite challenging. Teachers reported that their learners find it difficult to comprehend phenomena associated with electromagnetism, thus making it difficult for their learners to grasp concepts associated with it. Lack of resources to do practical activities in the topic of electromagnetism was found to be a major contributing factor to teaching and learning of this topic. The use of easily accessible materials among teachers was found to be very limited. Easily accessible locally sourced materials were found to have the potential to enable grade 10 Physical Science teachers to help learners to make sense of concepts of electromagnetism in under-resourced schools. In light of the above findings, the study recommends that science teachers should make use of easily accessible materials which can minimise their dependence on standard laboratory equipment which is unaffordable anyway by most schools.
- Full Text:
- Authors: Samuel, Paulo
- Date: 2017
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/8143 , vital:21359
- Description: This study sought to explore teachers’ perceptions and experiences of using easily accessible materials and how they might collaboratively develop learning and teaching support materials using easily accessible materials. The study explored three aspects. Firstly, the views, experiences and factors which influence grade 10 Physical Science teachers’ perceptions and experiences of teaching the topic of electromagnetism. Secondly, to find out what teachers can do to improve teaching and learning of electromagnetism in grade 10 Physical Science using easily accessible materials. Thirdly, to look at what enables or constrains grade 10 Physical Science teachers in under-resourced schools when dealing with electromagnetism, from using easily accessible materials. A qualitative method approach was adopted, underpinned by an interpretive paradigm but using some quantitative methods as well. Within the interpretive paradigm a case study approach was used. The study was carried out in Swakopmund and Gobabis education circuits of the Erongo and Omaheke Regions respectively. Data were collected using questionnaires, lesson observations and stimulated-recall interviews. The data obtained were validated in two ways, firstly, by triangulation from different data gathering techniques, and secondly, validation was done by member checking of the transcripts. To make meaning from the data generated, Vygotsky’s (1978) socio-cultural theory was used as a lens to analyse the data. The quantitative data generated were presented in figures, tables; whereas the qualitative data were coded inductively into descriptive texts to make meaning. It was found that teachers’s perceptions and experiences are that the topic of electromagnetism is quite challenging. Teachers reported that their learners find it difficult to comprehend phenomena associated with electromagnetism, thus making it difficult for their learners to grasp concepts associated with it. Lack of resources to do practical activities in the topic of electromagnetism was found to be a major contributing factor to teaching and learning of this topic. The use of easily accessible materials among teachers was found to be very limited. Easily accessible locally sourced materials were found to have the potential to enable grade 10 Physical Science teachers to help learners to make sense of concepts of electromagnetism in under-resourced schools. In light of the above findings, the study recommends that science teachers should make use of easily accessible materials which can minimise their dependence on standard laboratory equipment which is unaffordable anyway by most schools.
- Full Text:
Synthesis and photophysical studies of crown ether-bodipy dyes and the fabrication of bodipy embedded fluorescent nanofibers
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
- Full Text:
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
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Investigating teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in 'Grades 5-7': a Namibian case study
- Authors: Iiyambo,Julia
- Date: 2016
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/1296 , vital:20044
- Description: This study investigated teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in ‘grades 5 – 7’. Three teachers were involved in the study and the main goal was to explore how teachers might work with the additional tools of multiple representations to improve the teaching of fractions for conceptual understanding. Different types of multiple representations such as written mathematical symbols, descriptive written words, pictorial representations, manipulations, concrete reality, oral representations, and experience-based representations and videos or power point presentations were examined. This investigation was carried out through a focus group workshop developed by the researcher and though observations of fraction teaching which took place in schools. The research focused on the teachers working to develop their use of multiple representations to teach fractions and how they implemented what they learned in the workshop into their own classroom teaching. This study was conducted using a qualitative case study design and was oriented in the interpretive paradigm. The three participating teachers in the focus group workshop were observed and interviewed individually. The purpose of observing teaching before the workshop was to observe how the selected teachers taught fractions and in particular to observe which types of representations they used and how these were used to enhance the conceptual understanding of the learners. Post teaching took place after the focus group workshop and the different multiple representations which were used in different lessons were observed and analyzed. The purpose of the interview was to gain an understanding of the teachers’ views of using multiple representations when teaching fractions for conceptual understanding. The data showed that teachers who participated in the focus group workshop worked positively to develop their use of multiple representations to teach fractions. They made sense of fractions and were able to look at representations in different ways to develop the meaning and concepts of fractions. Teachers developed an understanding of working with multiple representations and were able to make connections among concepts and the use of concrete representations. Teachers also developed their lesson plans effectively to involve a variety of teaching methods and multiple representations, despite the limited time available to them. Moreover, teachers used different modes of representation to improve learner engagement in learning activities. Lastly, teachers used multiple representations to teach in ways that improved the learners’ conception of fractions. On the basis of this research, it can be concluded that in-service workshops for teachers on the integration of multiple representative tools in the teaching of ‘Grades 5 – 7’ fractions could provide a valuable contribution to further developing the teaching of fractions in schools.
- Full Text:
- Authors: Iiyambo,Julia
- Date: 2016
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/1296 , vital:20044
- Description: This study investigated teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in ‘grades 5 – 7’. Three teachers were involved in the study and the main goal was to explore how teachers might work with the additional tools of multiple representations to improve the teaching of fractions for conceptual understanding. Different types of multiple representations such as written mathematical symbols, descriptive written words, pictorial representations, manipulations, concrete reality, oral representations, and experience-based representations and videos or power point presentations were examined. This investigation was carried out through a focus group workshop developed by the researcher and though observations of fraction teaching which took place in schools. The research focused on the teachers working to develop their use of multiple representations to teach fractions and how they implemented what they learned in the workshop into their own classroom teaching. This study was conducted using a qualitative case study design and was oriented in the interpretive paradigm. The three participating teachers in the focus group workshop were observed and interviewed individually. The purpose of observing teaching before the workshop was to observe how the selected teachers taught fractions and in particular to observe which types of representations they used and how these were used to enhance the conceptual understanding of the learners. Post teaching took place after the focus group workshop and the different multiple representations which were used in different lessons were observed and analyzed. The purpose of the interview was to gain an understanding of the teachers’ views of using multiple representations when teaching fractions for conceptual understanding. The data showed that teachers who participated in the focus group workshop worked positively to develop their use of multiple representations to teach fractions. They made sense of fractions and were able to look at representations in different ways to develop the meaning and concepts of fractions. Teachers developed an understanding of working with multiple representations and were able to make connections among concepts and the use of concrete representations. Teachers also developed their lesson plans effectively to involve a variety of teaching methods and multiple representations, despite the limited time available to them. Moreover, teachers used different modes of representation to improve learner engagement in learning activities. Lastly, teachers used multiple representations to teach in ways that improved the learners’ conception of fractions. On the basis of this research, it can be concluded that in-service workshops for teachers on the integration of multiple representative tools in the teaching of ‘Grades 5 – 7’ fractions could provide a valuable contribution to further developing the teaching of fractions in schools.
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The potential economic implications of black locust (Robinia pseudoacacia l.) on agricultural production in South Africa
- Authors: Humphrey, Luke
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4069 , vital:20599
- Description: Black Locust (Robinia pseudoacacia L.) is an invasive deciduous, strongly suckering, broad- leaved tree that has the potential to be widely distributed across a large portion of South Africa. Robinia pseudoacacia has invaded all nine of South African provinces, with large infestations found in the Eastern Cape, Kwa Zulu-Natal, Free State and Gauteng provinces. The invasive tree has the potential to spread into livestock grazing lands in South Africa. Because R. pseudoacacia has the ability to spread and thrive in a variety of habitats and resists control, the distribution of the invasive tree into grazing land poses a problem for landowners. The potential economic impacts of R. pseudoacacia on agricultural production stem from the trees ability to reduce the carrying capacity of livestock. This study estimated the potential economic implications of R. pseudoacacia on agricultural production in South Africa, specifically looking at the livestock sector. The prevalence of R. pseudoacacia potential distribution was calculated by using a maximum-entropy predictive habitat model, MAXENT. The distribution of livestock, based on grazing capacity (ha/LSU), in South Africa was then determined. The potential direct economic impacts were estimated by assessing the impact of the potential distribution of R. pseudoacacia on the carrying capacity of livestock. The results showed that an infestation of R. pseudoacacia has the potential to reduce the gross margin in the livestock sector by between approximately R130 million and R961 million, dependent on the probability of invasion. Therefore, the potential invasion of R. pseudoacacia can have detrimental effects on the livestock sector in South Africa. The potential high levels of foregone income and business activity found in this study reaffirm the need to devote resources to develop a viable, economical and effective control method, such as biological control.
- Full Text:
- Authors: Humphrey, Luke
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4069 , vital:20599
- Description: Black Locust (Robinia pseudoacacia L.) is an invasive deciduous, strongly suckering, broad- leaved tree that has the potential to be widely distributed across a large portion of South Africa. Robinia pseudoacacia has invaded all nine of South African provinces, with large infestations found in the Eastern Cape, Kwa Zulu-Natal, Free State and Gauteng provinces. The invasive tree has the potential to spread into livestock grazing lands in South Africa. Because R. pseudoacacia has the ability to spread and thrive in a variety of habitats and resists control, the distribution of the invasive tree into grazing land poses a problem for landowners. The potential economic impacts of R. pseudoacacia on agricultural production stem from the trees ability to reduce the carrying capacity of livestock. This study estimated the potential economic implications of R. pseudoacacia on agricultural production in South Africa, specifically looking at the livestock sector. The prevalence of R. pseudoacacia potential distribution was calculated by using a maximum-entropy predictive habitat model, MAXENT. The distribution of livestock, based on grazing capacity (ha/LSU), in South Africa was then determined. The potential direct economic impacts were estimated by assessing the impact of the potential distribution of R. pseudoacacia on the carrying capacity of livestock. The results showed that an infestation of R. pseudoacacia has the potential to reduce the gross margin in the livestock sector by between approximately R130 million and R961 million, dependent on the probability of invasion. Therefore, the potential invasion of R. pseudoacacia can have detrimental effects on the livestock sector in South Africa. The potential high levels of foregone income and business activity found in this study reaffirm the need to devote resources to develop a viable, economical and effective control method, such as biological control.
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An exploration of the school nutrition programme's potential to catalyse community-based environmental learning : a case study of a rural Eastern Cape school
- Authors: Tshabeni, Veliswa
- Date: 2015
- Subjects: National School Nutrition Programme (South Africa) , School children -- Food -- South Africa -- Eastern Cape , Children -- Nutrition -- South Africa -- Eastern Cape , Environmental education -- South Africa -- Eastern Cape , Social learning -- South Africa -- Eastern Cape , Food security -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Poverty -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2063 , http://hdl.handle.net/10962/d1020306
- Description: The purpose of this study was to explore the extent to which a School Nutrition Programme can catalyse community-based environmental learning and promote food security in the school and the community. This is an interpretive case study of a junior secondary school in the rural Eastern Cape province of South Africa. The school is located in an area characterised by high levels of poverty and under-nutrition. The school’s food garden, a central focus of this study, contributes to the School Nutrition Programme, which falls under the National School Nutrition Programme (NSNP). The aim of the NSNP is to alleviate poverty in public schools. This case study was conducted by means of questionnaires, semi-structured interviews, and document analysis and field observations. The data set was analysed, firstly, to ascertain if the School Nutrition Programme functions as a community of practise (Wenger, 1998). Thereafter, the data set was analysed to identify the knowledge related to food security and environmental sustainability that is learned and shared in the School Nutrition Programme, and also how such learning took place. The study found that the School’s Nutrition Programme was indeed operating as a community of practice and that it created a platform for sharing explicit and tacit knowledge and skills related to food security and environmental sustainability. The case study also revealed the contextual and experience-based nature of knowledge related to food cultivation.
- Full Text:
- Authors: Tshabeni, Veliswa
- Date: 2015
- Subjects: National School Nutrition Programme (South Africa) , School children -- Food -- South Africa -- Eastern Cape , Children -- Nutrition -- South Africa -- Eastern Cape , Environmental education -- South Africa -- Eastern Cape , Social learning -- South Africa -- Eastern Cape , Food security -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Poverty -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2063 , http://hdl.handle.net/10962/d1020306
- Description: The purpose of this study was to explore the extent to which a School Nutrition Programme can catalyse community-based environmental learning and promote food security in the school and the community. This is an interpretive case study of a junior secondary school in the rural Eastern Cape province of South Africa. The school is located in an area characterised by high levels of poverty and under-nutrition. The school’s food garden, a central focus of this study, contributes to the School Nutrition Programme, which falls under the National School Nutrition Programme (NSNP). The aim of the NSNP is to alleviate poverty in public schools. This case study was conducted by means of questionnaires, semi-structured interviews, and document analysis and field observations. The data set was analysed, firstly, to ascertain if the School Nutrition Programme functions as a community of practise (Wenger, 1998). Thereafter, the data set was analysed to identify the knowledge related to food security and environmental sustainability that is learned and shared in the School Nutrition Programme, and also how such learning took place. The study found that the School’s Nutrition Programme was indeed operating as a community of practice and that it created a platform for sharing explicit and tacit knowledge and skills related to food security and environmental sustainability. The case study also revealed the contextual and experience-based nature of knowledge related to food cultivation.
- Full Text:
A discussion and comparison of company legislation and tax legislation in South Africa, in relation to amalgamations and mergers
- Authors: Sloane, Justin
- Date: 2014
- Subjects: Corporation law -- South Africa , Taxation -- Law and legislation -- South Africa , Consolidation and merger of corporations -- South Africa , Income tax -- South Africa , Capital gains tax -- South Africa , Value-added tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:908 , http://hdl.handle.net/10962/d1013028
- Description: In his 2012 Budget Review, the Minister of Finance, Pravin Gordhan acknowledged that the introduction of the "new" Companies Act had given rise to certain anomalies in relation to tax and subsequently announced that the South African government would undertake to review the nature of company mergers, acquisitions and other restructurings with the view of possibly amending the Income Tax Act and/or the "new" Companies Act, to bring the two legislations in line with one another. These anomalies give rise to the present research. The literature reviewed in the present research revealed and identified the inconsistencies that exist between the "new" Companies Act, 71 of 2008 and the Income Tax Act, 58 of 1962, specifically the inconsistencies that exist in respect of the newly introduced amalgamation or merger provisions as set out in the "new" Companies Act. Moreover, this research was undertaken to identify the potential tax implications insofar as they relate to amalgamation transactions and, in particular, the potential tax implications where such transactions, because of the anomalies, fall outside the ambit section 44 of the Income Tax Act, which would in normal circumstances provide for tax "rollover relief". In this regard, the present research identified the possible income tax, capital gains tax, value-added tax, transfer duty tax and securities transfer tax affected by an amalgamation transaction, on the assumption that the "rollover relief" in section 44 of the Income Tax Act does not apply.
- Full Text:
- Authors: Sloane, Justin
- Date: 2014
- Subjects: Corporation law -- South Africa , Taxation -- Law and legislation -- South Africa , Consolidation and merger of corporations -- South Africa , Income tax -- South Africa , Capital gains tax -- South Africa , Value-added tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:908 , http://hdl.handle.net/10962/d1013028
- Description: In his 2012 Budget Review, the Minister of Finance, Pravin Gordhan acknowledged that the introduction of the "new" Companies Act had given rise to certain anomalies in relation to tax and subsequently announced that the South African government would undertake to review the nature of company mergers, acquisitions and other restructurings with the view of possibly amending the Income Tax Act and/or the "new" Companies Act, to bring the two legislations in line with one another. These anomalies give rise to the present research. The literature reviewed in the present research revealed and identified the inconsistencies that exist between the "new" Companies Act, 71 of 2008 and the Income Tax Act, 58 of 1962, specifically the inconsistencies that exist in respect of the newly introduced amalgamation or merger provisions as set out in the "new" Companies Act. Moreover, this research was undertaken to identify the potential tax implications insofar as they relate to amalgamation transactions and, in particular, the potential tax implications where such transactions, because of the anomalies, fall outside the ambit section 44 of the Income Tax Act, which would in normal circumstances provide for tax "rollover relief". In this regard, the present research identified the possible income tax, capital gains tax, value-added tax, transfer duty tax and securities transfer tax affected by an amalgamation transaction, on the assumption that the "rollover relief" in section 44 of the Income Tax Act does not apply.
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Intimacy, sex and sexuality : the experiences of vertically-infected HIV-positive adolescents
- Authors: Smaill, Lindsay Ann
- Date: 2014
- Subjects: Teenagers -- Sexual behavior , HIV-positive youth -- South Africa -- Eastern Cape , HIV infections -- Social aspects -- South Africa -- Eastern Cape , HIV infections -- Transmission -- South Africa -- Eastern Cape , Teenagers -- Diseases -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3225 , http://hdl.handle.net/10962/d1013026
- Description: This research explores the lived experience of being a vertically or prenatally-infected HIV-positive adolescent. It looks specifically at how the participants experience intimacy, sex and sexuality. HIV/AIDS remains a global pandemic and vertically-infected adolescents are a growing new demographic. However, there is a poverty of research, and therefore interventions and support, for this demographic. This qualitative research conducted six individual, in-depth, semi-structured, psychoanalytic research interviews with three participants. The interviews were structured around projective drawings that the participants did in the course of each interview. The interviews were transcribed and analysed using psychodynamic object relations theory and organised through interpretative phenomenological analysis. Every effort was made to ensure that the research was conducted ethically and validly. The analysis found that the participants' experience of intimacy has resulted in a self that is constantly under threat. This in turn has negatively impacted on the participants' experience of sex and sexuality. The implication of this research is that more in-depth research needs to be done into this demographic so that better interventions and support may be offered.
- Full Text:
- Authors: Smaill, Lindsay Ann
- Date: 2014
- Subjects: Teenagers -- Sexual behavior , HIV-positive youth -- South Africa -- Eastern Cape , HIV infections -- Social aspects -- South Africa -- Eastern Cape , HIV infections -- Transmission -- South Africa -- Eastern Cape , Teenagers -- Diseases -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3225 , http://hdl.handle.net/10962/d1013026
- Description: This research explores the lived experience of being a vertically or prenatally-infected HIV-positive adolescent. It looks specifically at how the participants experience intimacy, sex and sexuality. HIV/AIDS remains a global pandemic and vertically-infected adolescents are a growing new demographic. However, there is a poverty of research, and therefore interventions and support, for this demographic. This qualitative research conducted six individual, in-depth, semi-structured, psychoanalytic research interviews with three participants. The interviews were structured around projective drawings that the participants did in the course of each interview. The interviews were transcribed and analysed using psychodynamic object relations theory and organised through interpretative phenomenological analysis. Every effort was made to ensure that the research was conducted ethically and validly. The analysis found that the participants' experience of intimacy has resulted in a self that is constantly under threat. This in turn has negatively impacted on the participants' experience of sex and sexuality. The implication of this research is that more in-depth research needs to be done into this demographic so that better interventions and support may be offered.
- Full Text:
Valuation of banks in emerging markets: an exploratory study
- Authors: Sabilika, Keith
- Date: 2014
- Subjects: Banks and banking -- Valuation , Banks and banking -- Valuation -- Developing countries , Discounted cash flow , Capital assets pricing model , Capital -- Developing countries
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1200 , http://hdl.handle.net/10962/d1013057
- Description: Practitioners and academics in emerging markets are yet to agree on how best they can value companies in emerging markets. In contrast, academics and practitioners in developed markets seem to agree on mainstream valuation practices (Bruner, Eades, Harris and Haggins, 1998; Graham and Harvey, 2001). This study was therefore aimed at achieving such consensus with particular attention being paid to the emerging market banks. Emerging market banks are by no means small and are growing fast. Furthermore, these banks are currently involved in lots of cutting age economic activities such as mergers and acquisitions (M&A), joint ventures and strategic alliances which require sound valuation practices that are based on empirical evidence. The primary purpose of this research was to establish consensus of opinion among experts with regard to the valuation of banks in emerging markets. To achieve the purpose of this study the Delphi technique, which is a structured survey method that relies on a panel of experts to answer questionnaires in two or more Delphi rounds, was used to gather data and develop consensus among experts (Kalaian and Kasim, 2012). The main findings in this study pertain to aspects concerning the type of analysis considered by experts when analysing the performance of banks, how experts compare the discounted cash flow (DCF) approach to multiples valuation approach, the challenges encountered by experts when valuing banks in emerging markets, and how experts compute the cost of capital for banks in emerging markets. The main findings of this study can be summarised as follows: ∙ When analyzing the performance of banks, it is essential to conduct a bank-specific, industry and macroeconomic analysis; ∙ When estimating the future performance of banks, the time series analysis and an explicit forecast period of between 4-10 years may be used; ∙ When estimating the terminal value for banks in emerging markets, the perpetuity with growth is used; ∙ When computing the value for banks, the DCF valuation approach (equity DCF and DDM valuation models) are used as primary valuation methods and the relative valuation approach (P/E and P/BV ratio) are used as secondary valuation methods; ∙ The DCF valuation approach is considered as more accurate and popular when valuing banks in emerging markets; and ∙ When estimating the cost of equity, the capital asset pricing model (CAPM) is used.
- Full Text:
- Authors: Sabilika, Keith
- Date: 2014
- Subjects: Banks and banking -- Valuation , Banks and banking -- Valuation -- Developing countries , Discounted cash flow , Capital assets pricing model , Capital -- Developing countries
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1200 , http://hdl.handle.net/10962/d1013057
- Description: Practitioners and academics in emerging markets are yet to agree on how best they can value companies in emerging markets. In contrast, academics and practitioners in developed markets seem to agree on mainstream valuation practices (Bruner, Eades, Harris and Haggins, 1998; Graham and Harvey, 2001). This study was therefore aimed at achieving such consensus with particular attention being paid to the emerging market banks. Emerging market banks are by no means small and are growing fast. Furthermore, these banks are currently involved in lots of cutting age economic activities such as mergers and acquisitions (M&A), joint ventures and strategic alliances which require sound valuation practices that are based on empirical evidence. The primary purpose of this research was to establish consensus of opinion among experts with regard to the valuation of banks in emerging markets. To achieve the purpose of this study the Delphi technique, which is a structured survey method that relies on a panel of experts to answer questionnaires in two or more Delphi rounds, was used to gather data and develop consensus among experts (Kalaian and Kasim, 2012). The main findings in this study pertain to aspects concerning the type of analysis considered by experts when analysing the performance of banks, how experts compare the discounted cash flow (DCF) approach to multiples valuation approach, the challenges encountered by experts when valuing banks in emerging markets, and how experts compute the cost of capital for banks in emerging markets. The main findings of this study can be summarised as follows: ∙ When analyzing the performance of banks, it is essential to conduct a bank-specific, industry and macroeconomic analysis; ∙ When estimating the future performance of banks, the time series analysis and an explicit forecast period of between 4-10 years may be used; ∙ When estimating the terminal value for banks in emerging markets, the perpetuity with growth is used; ∙ When computing the value for banks, the DCF valuation approach (equity DCF and DDM valuation models) are used as primary valuation methods and the relative valuation approach (P/E and P/BV ratio) are used as secondary valuation methods; ∙ The DCF valuation approach is considered as more accurate and popular when valuing banks in emerging markets; and ∙ When estimating the cost of equity, the capital asset pricing model (CAPM) is used.
- Full Text:
Making sense of the lived and told experience of the 'ill' body : a phenomenological exploration into the storied and embodied nature of somatic or medically unexplained symtoms
- Authors: Haggard, Claire Louise
- Date: 2013-07-25
- Subjects: Psychological manifestations of general disease Somatization disorder Physician and patient -- Case studies
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3185 , http://hdl.handle.net/10962/d1008364
- Description: Despite a wealth of literature on the aetiology of somatic distress or somatization, somatic theory has failed to expand beyond a dualistic epistemology of causation. Within the primary health context where medically unexplained symptoms are characteristically articulated as literal, symbolic gestures of internal psychological processes, individuals' subjective accounts of somatic distress are reduced to objective phenomena and thus articulated on the grounds of absence. Within this context, the body as a lived, meaningful, perceiving subjectivity is silenced in favour of the corpse, thus rendering the somatizing individual's lived and subjective experience, expression and knowledge of somatic distress inaccessible. Instead, the somatizing individual is positioned within a domain of perturbed silence - a domain in which the professional's turning away or retreat from engaging somatization on the grounds of unique, subjective and corporeal experience, positions the patient/client as a passive, silent recipient whose somatic expressions as lived are overlooked. This study attempts to initiate a theoretical focus of departure from existing articulations of somatic distress through the development of a theoretical and epistemological framework that addresses some of the tensions inherent to contemporary somatic theory. In so doing, it employs embodiment philosophy and narrative methodology as a basis for a preliminary and critical investigation into a relatively neglected area of somatization research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Authors: Haggard, Claire Louise
- Date: 2013-07-25
- Subjects: Psychological manifestations of general disease Somatization disorder Physician and patient -- Case studies
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3185 , http://hdl.handle.net/10962/d1008364
- Description: Despite a wealth of literature on the aetiology of somatic distress or somatization, somatic theory has failed to expand beyond a dualistic epistemology of causation. Within the primary health context where medically unexplained symptoms are characteristically articulated as literal, symbolic gestures of internal psychological processes, individuals' subjective accounts of somatic distress are reduced to objective phenomena and thus articulated on the grounds of absence. Within this context, the body as a lived, meaningful, perceiving subjectivity is silenced in favour of the corpse, thus rendering the somatizing individual's lived and subjective experience, expression and knowledge of somatic distress inaccessible. Instead, the somatizing individual is positioned within a domain of perturbed silence - a domain in which the professional's turning away or retreat from engaging somatization on the grounds of unique, subjective and corporeal experience, positions the patient/client as a passive, silent recipient whose somatic expressions as lived are overlooked. This study attempts to initiate a theoretical focus of departure from existing articulations of somatic distress through the development of a theoretical and epistemological framework that addresses some of the tensions inherent to contemporary somatic theory. In so doing, it employs embodiment philosophy and narrative methodology as a basis for a preliminary and critical investigation into a relatively neglected area of somatization research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
Understandings of citizenship in policy and amongst matric learners in three KwaZulu Natal schools
- Authors: Van Lelyveld, Lara Diane
- Date: 2013
- Subjects: Citizenship -- Study and teaching -- Kwazulu-Natal (South Africa) Citizenship -- Social aspects -- Kwazulu-Natal (South Africa)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2847 , http://hdl.handle.net/10962/d1006116
- Description: This thesis explores the difference between the vision of citizenship within education policy and the actual experiences and understandings of citizenship by Matric learners. Citizenship as envisioned in policy is shown to differ significantly to citizenship as understood and experienced by the interview participants. The citizenship envisioned in policy presents the goal of an equal and united citizenry whereas interview participants described citizenship as unequal and hierarchical. In particular, the racial hierarchy enforced under Apartheid was found to dominate the learners’ experiences of citizenship. Despite progressive legislation, distribution of opportunities remains heavily weighted in favour of those in high-income environments. Education policies that determine the overall structure of the South African education system were selected for analysis. These are the Constitution, the South African Schools Act and the National Education Policy Act. These policies are analysed and a vision of South African citizenship is described as possessing the following characteristics. A common, equal citizenship in a united and transformed South Africa. A citizenship encouraging and mandating critical engagement, dialogue, openness and transparency. A citizenship founded on quality of life for all and developing the potential of each individual. A citizenship in which both state and citizen are responsible and accountable and operate within the rule of law. A citizenship underpinned by human dignity and freedom and security of the person. A citizenship in which there is respect for difference and self-determination and in which ‘unity in diversity’ plays a key role. Matric learners were drawn from three different schools in an area of Kwazulu-Natal. Each of these schools represents a ‘type’ of school in South Africa: a former Model C school, an independent school and a school based in a rural or township area. The interviews aimed not only to understand citizenship from the perspective of these learners, but also to understand how experiences of citizenship varied depending on race, gender and class.
- Full Text:
- Authors: Van Lelyveld, Lara Diane
- Date: 2013
- Subjects: Citizenship -- Study and teaching -- Kwazulu-Natal (South Africa) Citizenship -- Social aspects -- Kwazulu-Natal (South Africa)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2847 , http://hdl.handle.net/10962/d1006116
- Description: This thesis explores the difference between the vision of citizenship within education policy and the actual experiences and understandings of citizenship by Matric learners. Citizenship as envisioned in policy is shown to differ significantly to citizenship as understood and experienced by the interview participants. The citizenship envisioned in policy presents the goal of an equal and united citizenry whereas interview participants described citizenship as unequal and hierarchical. In particular, the racial hierarchy enforced under Apartheid was found to dominate the learners’ experiences of citizenship. Despite progressive legislation, distribution of opportunities remains heavily weighted in favour of those in high-income environments. Education policies that determine the overall structure of the South African education system were selected for analysis. These are the Constitution, the South African Schools Act and the National Education Policy Act. These policies are analysed and a vision of South African citizenship is described as possessing the following characteristics. A common, equal citizenship in a united and transformed South Africa. A citizenship encouraging and mandating critical engagement, dialogue, openness and transparency. A citizenship founded on quality of life for all and developing the potential of each individual. A citizenship in which both state and citizen are responsible and accountable and operate within the rule of law. A citizenship underpinned by human dignity and freedom and security of the person. A citizenship in which there is respect for difference and self-determination and in which ‘unity in diversity’ plays a key role. Matric learners were drawn from three different schools in an area of Kwazulu-Natal. Each of these schools represents a ‘type’ of school in South Africa: a former Model C school, an independent school and a school based in a rural or township area. The interviews aimed not only to understand citizenship from the perspective of these learners, but also to understand how experiences of citizenship varied depending on race, gender and class.
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Fast track land reform programme and women in Goromonzi district, Zimbabwe
- Authors: Chakona, Loveness
- Date: 2012
- Subjects: Land reform -- Research -- Zimbabwe Land settlement -- Government policy -- Zimbabwe Land reform beneficiaries -- Zimbabwe Sex discrimination against women -- Zimbabwe Women's rights -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3317 , http://hdl.handle.net/10962/d1003105
- Description: From the year 2000, land became the key signifier for tackling the unfinished business of the decolonisation process in Zimbabwe, notably by rectifying the racially-based land injustices of the past through land redistribution. This took the form of the Fast Track Land Reform Programme (FTLRP). However, the racialised character and focus of the FTLRP tended to mask or at least downplay important gender dimensions to land in Zimbabwe. Colonial and post-colonial Zimbabwe (up to 2000) had instigated, propagated and reproduced land ownership, control and access along a distinctively patriarchal basis which left women either totally excluded or incorporated in an oppressive manner. This patriarchal structuring of the land question was rooted in institutions, practices and discourses. Although a burgeoning number of studies have been undertaken on the FTLRP, few have had a distinctively gender focus in seeking to identify, examine and assess the effect of the programme on patriarchal relations and the socio-economic livelihoods of rural women. This thesis makes a contribution to filling this lacuna by offering an empirically-rich study of land redistribution in one particular district in Zimbabwe, namely, Goromonzi District. This entails a focus on women on A1 resettlement farms in the district (and specifically women who came from nearby customary areas) and on women who continue to live in customary areas in the district. My thesis concludes that the FTLRP is seriously flawed in terms of addressing and tackling the patriarchal structures that underpin the Zimbabwean land question.
- Full Text:
- Authors: Chakona, Loveness
- Date: 2012
- Subjects: Land reform -- Research -- Zimbabwe Land settlement -- Government policy -- Zimbabwe Land reform beneficiaries -- Zimbabwe Sex discrimination against women -- Zimbabwe Women's rights -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3317 , http://hdl.handle.net/10962/d1003105
- Description: From the year 2000, land became the key signifier for tackling the unfinished business of the decolonisation process in Zimbabwe, notably by rectifying the racially-based land injustices of the past through land redistribution. This took the form of the Fast Track Land Reform Programme (FTLRP). However, the racialised character and focus of the FTLRP tended to mask or at least downplay important gender dimensions to land in Zimbabwe. Colonial and post-colonial Zimbabwe (up to 2000) had instigated, propagated and reproduced land ownership, control and access along a distinctively patriarchal basis which left women either totally excluded or incorporated in an oppressive manner. This patriarchal structuring of the land question was rooted in institutions, practices and discourses. Although a burgeoning number of studies have been undertaken on the FTLRP, few have had a distinctively gender focus in seeking to identify, examine and assess the effect of the programme on patriarchal relations and the socio-economic livelihoods of rural women. This thesis makes a contribution to filling this lacuna by offering an empirically-rich study of land redistribution in one particular district in Zimbabwe, namely, Goromonzi District. This entails a focus on women on A1 resettlement farms in the district (and specifically women who came from nearby customary areas) and on women who continue to live in customary areas in the district. My thesis concludes that the FTLRP is seriously flawed in terms of addressing and tackling the patriarchal structures that underpin the Zimbabwean land question.
- Full Text:
The synthesis of fructooligosaccharides by the fructofuranosidase FopAp from Aspergillus niger
- Pindura, Mitchell Kingsley Chido
- Authors: Pindura, Mitchell Kingsley Chido
- Date: 2012
- Subjects: Aspergillus niger , Oligosaccharides
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4158 , http://hdl.handle.net/10962/d1018267
- Description: Fructooligosaccharides (FOS) are short-chain fructans with a terminal glucose moiety and are found naturally in many plant species. Besides their wide use as an alternative sweetener in food and beverage industry, FOS have shown great potential as neutraceuticals against diabetes, colon cancer and bowel disease. The uses of FOS are dependent on the degree of polymerisation that they exhibit. β-fructofuranosidase (FFase) and fructosyltransferase (FTase) enzymes are capable of synthesing FOS from carbohydrate raw materials such as chicory and sugar beet. The aim of this study was to investigate the synthesis of FOS of a pre-defined chain length, from sucrose, by the enzyme FopAp; a β-fructofuranosidase from Aspergillus niger. ATCC 20611. The crude enzyme FopAp was successfully purified, with a yield of 78.20 %, by ammonium sulphate precipitation and anion exchange chromatography. Two protein fractions, named FA and FB were shown to exhibit FFase activity. SDS PAGE analysis revealed two proteins with molecular weights of 112 kDa and 78 kDa, which were identified as a FFase and a hydrolase. Temperature and pH optima of 20 ºC and 9, respectively, were observed for the transfructosylation activity in the FFase. The purified FFase exhibited a half life of 1.5 hrs under optimal conditions. Substrate kinetic studies indicated a high hydrolytic activity at low sucrose concentrations, with Vmax and Km of 1.25 μmol/ml/min and 3.28 mM, respectively. Analysis by response surface methodology identified temperature and pH to be significant factors for the production of kestose and nystose, at a 95 % level of confidence. These findings were confirmed by neural networks constructed to identify optimal conditions of FOS synthesis.FOS synthesis was found to be optimal between pH 6 and pH 9 at 25 ºC. The factor of reaction time was found to be insignificant within the selected experimental constraints, for both FOS species. The findings of this investigation are very important as the foundations of a commercially viable synthetic process for the production of FOS.
- Full Text:
- Authors: Pindura, Mitchell Kingsley Chido
- Date: 2012
- Subjects: Aspergillus niger , Oligosaccharides
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4158 , http://hdl.handle.net/10962/d1018267
- Description: Fructooligosaccharides (FOS) are short-chain fructans with a terminal glucose moiety and are found naturally in many plant species. Besides their wide use as an alternative sweetener in food and beverage industry, FOS have shown great potential as neutraceuticals against diabetes, colon cancer and bowel disease. The uses of FOS are dependent on the degree of polymerisation that they exhibit. β-fructofuranosidase (FFase) and fructosyltransferase (FTase) enzymes are capable of synthesing FOS from carbohydrate raw materials such as chicory and sugar beet. The aim of this study was to investigate the synthesis of FOS of a pre-defined chain length, from sucrose, by the enzyme FopAp; a β-fructofuranosidase from Aspergillus niger. ATCC 20611. The crude enzyme FopAp was successfully purified, with a yield of 78.20 %, by ammonium sulphate precipitation and anion exchange chromatography. Two protein fractions, named FA and FB were shown to exhibit FFase activity. SDS PAGE analysis revealed two proteins with molecular weights of 112 kDa and 78 kDa, which were identified as a FFase and a hydrolase. Temperature and pH optima of 20 ºC and 9, respectively, were observed for the transfructosylation activity in the FFase. The purified FFase exhibited a half life of 1.5 hrs under optimal conditions. Substrate kinetic studies indicated a high hydrolytic activity at low sucrose concentrations, with Vmax and Km of 1.25 μmol/ml/min and 3.28 mM, respectively. Analysis by response surface methodology identified temperature and pH to be significant factors for the production of kestose and nystose, at a 95 % level of confidence. These findings were confirmed by neural networks constructed to identify optimal conditions of FOS synthesis.FOS synthesis was found to be optimal between pH 6 and pH 9 at 25 ºC. The factor of reaction time was found to be insignificant within the selected experimental constraints, for both FOS species. The findings of this investigation are very important as the foundations of a commercially viable synthetic process for the production of FOS.
- Full Text:
Media and parliament in the Third Republic: a study of newspaper coverage of parliament by the Times of Zambia and the Post from January to November 2001
- Authors: Djokotoe-Gliguie, Edem K
- Date: 2003
- Subjects: Newspapers -- Zambia Mass media -- Political aspects -- Zambia Zambia -- Politics and government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3515 , http://hdl.handle.net/10962/d1007796
- Description: The press is credited with playing a central role in the consolidation of democracy by informing citizens, engaging them in the process of public decision making and governance and stimulating wide and inclusive debate on public matters. In emergent democracies like Zambia, the extent of the media's role as a public sphere, not to mention its impact, is not known. The study set out to investigate the extent of the press' public sphere role, particularly how Zambian newspapers report Parliament and how such coverage informs public opinion. It found that though the press covers Parliament, the nature of coverage does not empower newspaper readers with the kind of context, background and interpretation they would otherwise need to engage in public discourses on matters that affect them from an informed perspective. In the main, the role of the press in informing citizens is not fully realised, not only because uninformative character of coverage, but partly because of low literacy levels and the limited reach of local newspapers. It was against this background that the study recommended ways in which the Zambian press could re-focus its approach to parliamentary news coverage to make it more informational and more inclined towards playing a public sphere role, at least to the newspaper-reading public. Making parliamentary coverage an integrated newsroom function was the main recommendation. It provided the basis for suggesting a practical editorial option for the coverage of the legislature that accommodates the integration of context, background and interpretation into parliamentary news.
- Full Text:
- Authors: Djokotoe-Gliguie, Edem K
- Date: 2003
- Subjects: Newspapers -- Zambia Mass media -- Political aspects -- Zambia Zambia -- Politics and government
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3515 , http://hdl.handle.net/10962/d1007796
- Description: The press is credited with playing a central role in the consolidation of democracy by informing citizens, engaging them in the process of public decision making and governance and stimulating wide and inclusive debate on public matters. In emergent democracies like Zambia, the extent of the media's role as a public sphere, not to mention its impact, is not known. The study set out to investigate the extent of the press' public sphere role, particularly how Zambian newspapers report Parliament and how such coverage informs public opinion. It found that though the press covers Parliament, the nature of coverage does not empower newspaper readers with the kind of context, background and interpretation they would otherwise need to engage in public discourses on matters that affect them from an informed perspective. In the main, the role of the press in informing citizens is not fully realised, not only because uninformative character of coverage, but partly because of low literacy levels and the limited reach of local newspapers. It was against this background that the study recommended ways in which the Zambian press could re-focus its approach to parliamentary news coverage to make it more informational and more inclined towards playing a public sphere role, at least to the newspaper-reading public. Making parliamentary coverage an integrated newsroom function was the main recommendation. It provided the basis for suggesting a practical editorial option for the coverage of the legislature that accommodates the integration of context, background and interpretation into parliamentary news.
- Full Text:
A study of perceptions, knowledge and understanding of desertification and its causes among decision makers in northern Namibia
- Tshikesho, Desiderius Raimund
- Authors: Tshikesho, Desiderius Raimund
- Date: 1996
- Subjects: Desertification Desertification -- Namibia Desertification -- Economic aspects -- Namibia Environmental education -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1779 , http://hdl.handle.net/10962/d1003664
- Description: This study was aimed at investigating the perceptions, knowledge and understanding of desertification and its causes among decision makers in northern Namibia. The focus of investigation was on desertification and its major causes as identified in the general literature, viz. deforestation, overgrazing and overcultivation. Particular attention was given to the socioeconomic and cultural factors which are behind these perceived 'ecological' causes of desertification. Furthermore, the respondents were also engaged in the generation of solutions to the problem of desertification and its causes. Data collection was based on semi-structured interviews with the regional governors, councillors and chief headmen from the four northern regions. A qualitative approach was adopted for the research and findings are essentially descriptive and qualitative. It is anticipated that the study will make an important contribution to the current debate on desertification in Namibia, specifically with regard to the perceptions, knowledge and understanding of desertification and its causes among the decision makers in northern Namibia.
- Full Text:
- Authors: Tshikesho, Desiderius Raimund
- Date: 1996
- Subjects: Desertification Desertification -- Namibia Desertification -- Economic aspects -- Namibia Environmental education -- Namibia
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1779 , http://hdl.handle.net/10962/d1003664
- Description: This study was aimed at investigating the perceptions, knowledge and understanding of desertification and its causes among decision makers in northern Namibia. The focus of investigation was on desertification and its major causes as identified in the general literature, viz. deforestation, overgrazing and overcultivation. Particular attention was given to the socioeconomic and cultural factors which are behind these perceived 'ecological' causes of desertification. Furthermore, the respondents were also engaged in the generation of solutions to the problem of desertification and its causes. Data collection was based on semi-structured interviews with the regional governors, councillors and chief headmen from the four northern regions. A qualitative approach was adopted for the research and findings are essentially descriptive and qualitative. It is anticipated that the study will make an important contribution to the current debate on desertification in Namibia, specifically with regard to the perceptions, knowledge and understanding of desertification and its causes among the decision makers in northern Namibia.
- Full Text:
Social constructivist mathematics education in a Ciskeian secondary school classroom
- Authors: Raghavan, Prasannakumary
- Date: 1994
- Subjects: Mathematics -- Curricula -- South Africa -- Ciskei -- Case studies Mathematics -- Study and teaching (Secondary) -- South Africa -- Ciskei
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1767 , http://hdl.handle.net/10962/d1003652
- Description: The researcher's experience as a high school mathematics teacher in several African countries convinced her that a good number of mathematics learners exhibit serious difficulties in conceptualising mathematics properly. Her experience in teaching the subject in the Ciskei since 1990 reinforced this conviction. The researcher's natural curiosity to probe into the causes of the poor state of mathematics education in the region served as the springboard into her investigation. Her thoughts developed in line with the emerging educational theories of social constructivism. This provided a conceptual framework for the solution of the problem, the feasibility of which was put to test practically in a Ciskeian classroom. She explicates that the difficulties experienced by the pupils in conceptualising mathematics are philosophically deep rooted and latent in the present system of mathematics education itself, which, in Ciskei, impedes the learners' conceptualisation owing to numerous problems related to their linguistic and cultural situatedness. In the analysis of the present system of mathematics education in the Ciskei she reviews a few recently published mathematics text books in the context of the topics chosen for her research study. The results of her classroom investigation establish that a possible solution to the problem lies in the social constructivist teaching approaches.
- Full Text:
- Authors: Raghavan, Prasannakumary
- Date: 1994
- Subjects: Mathematics -- Curricula -- South Africa -- Ciskei -- Case studies Mathematics -- Study and teaching (Secondary) -- South Africa -- Ciskei
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1767 , http://hdl.handle.net/10962/d1003652
- Description: The researcher's experience as a high school mathematics teacher in several African countries convinced her that a good number of mathematics learners exhibit serious difficulties in conceptualising mathematics properly. Her experience in teaching the subject in the Ciskei since 1990 reinforced this conviction. The researcher's natural curiosity to probe into the causes of the poor state of mathematics education in the region served as the springboard into her investigation. Her thoughts developed in line with the emerging educational theories of social constructivism. This provided a conceptual framework for the solution of the problem, the feasibility of which was put to test practically in a Ciskeian classroom. She explicates that the difficulties experienced by the pupils in conceptualising mathematics are philosophically deep rooted and latent in the present system of mathematics education itself, which, in Ciskei, impedes the learners' conceptualisation owing to numerous problems related to their linguistic and cultural situatedness. In the analysis of the present system of mathematics education in the Ciskei she reviews a few recently published mathematics text books in the context of the topics chosen for her research study. The results of her classroom investigation establish that a possible solution to the problem lies in the social constructivist teaching approaches.
- Full Text:
An examination of the use of the contextual question in examining Shakespeare's plays at the standard ten level in Cape Education Department schools
- Authors: Mullineux, Peter Newton
- Date: 1989
- Subjects: Shakespeare, William, 1564-1616 -- Study and teaching , English literature -- Examinations, questions, etc. , English literature -- Study and teaching (Secondary) -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1346 , http://hdl.handle.net/10962/d1001412
- Description: Six years as a sub-examiner of both literature and written work made me aware of a personal dissatisfaction with the system of examining. This research examines in detail the use of the contextual question in examining Shakespeare's plays. The main concern has been to try to deduce what constitutes a good set of contextual questions. This area appears to have attracted little detailed research. However, there is much general writing on the teaching of literature. There is no major conclusion in the dissertation but rather a series of conclusions related to the concept of the contextual question. These are summarised towards the end of chapter three. Some general recommendations appear at the end of chapter three as a sub-heading. The findings of this investigation indicate a need for further research into the system of examining literature in the Cape. It is hoped that teachers and examiners reading this dissertation will be able to use the findings to provide a possible framework for the setting of sound contextual questions
- Full Text:
- Authors: Mullineux, Peter Newton
- Date: 1989
- Subjects: Shakespeare, William, 1564-1616 -- Study and teaching , English literature -- Examinations, questions, etc. , English literature -- Study and teaching (Secondary) -- South Africa
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1346 , http://hdl.handle.net/10962/d1001412
- Description: Six years as a sub-examiner of both literature and written work made me aware of a personal dissatisfaction with the system of examining. This research examines in detail the use of the contextual question in examining Shakespeare's plays. The main concern has been to try to deduce what constitutes a good set of contextual questions. This area appears to have attracted little detailed research. However, there is much general writing on the teaching of literature. There is no major conclusion in the dissertation but rather a series of conclusions related to the concept of the contextual question. These are summarised towards the end of chapter three. Some general recommendations appear at the end of chapter three as a sub-heading. The findings of this investigation indicate a need for further research into the system of examining literature in the Cape. It is hoped that teachers and examiners reading this dissertation will be able to use the findings to provide a possible framework for the setting of sound contextual questions
- Full Text:
Vein and replacement type Sn and Sn-W mineralization in the Southern Kaoko Zone, Damara Province, South West Africa/Namibia
- Authors: Petzel, V
- Date: 1986
- Subjects: Geology, Structural -- Namibia -- Damara Mobile Belt , Geology, Structural -- Namibia -- Kaoko Belt , Veins (Geology) -- Namibia -- Damara Mobile Belt , Veins (Geology) -- Namibia -- Kaoko Belt , Mineralogy -- Namibia -- Damara Mobile Belt , Mineralogy -- Namibia -- Kaoko Belt , Geodynamics -- Namibia -- Damara Mobile Belt , Geodynamics -- Namibia -- Kaoko Belt
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5041 , http://hdl.handle.net/10962/d1007633
- Description: The ENE trending Brandberg West - Goantagab Sn-W belt is located in the Southern Kaoko Zone of the northern coastal branch of the Damara Orogen. The lithologies in this area are turbiditic and consist of three schist units separated by two marble horizons, all of which are correlated with the Swakop Group. The formations are intensely folded by at least three episodes of which the first two are coaxial and resulted in prominent, approximately N-S trending, structures. Sn and Sn-W mineralization predominantly occurs as vein and replacement type mineralization. Vein type mineralization occurs as Brandberg West, Frans Prospect, Gamigab Prospect and the Goantagab Mining Area. The vein type mineralization is accompanied by intense alteration, consisting of greisenization, sericitization, hematitization and carbonatization. Replacement-type, hematite-cassiterite mineralization, occurs in the Goantagab Mining area in the marble close to, or at the schist marble contact. Intense ferruginous alteration of the marbles in this area, is associated with veins, which terminate against, or cross cut the marble. A regional metal zonation, ranging from Sn-W mineralization with minor sulphides at Brandberg West to Sn-sulphide mineralization at Goantagab can be detected. This metal zonation is attributed to the distance of the mineral locality from the source area, with Goantagab representing a distal and Brandberg West a proximal position relative to the source area. Structural, mineralogical and geological features of the mineralization in this area suggest that processes of ore genesis may be related to anorogenic magmatism of Karoo age.
- Full Text:
- Authors: Petzel, V
- Date: 1986
- Subjects: Geology, Structural -- Namibia -- Damara Mobile Belt , Geology, Structural -- Namibia -- Kaoko Belt , Veins (Geology) -- Namibia -- Damara Mobile Belt , Veins (Geology) -- Namibia -- Kaoko Belt , Mineralogy -- Namibia -- Damara Mobile Belt , Mineralogy -- Namibia -- Kaoko Belt , Geodynamics -- Namibia -- Damara Mobile Belt , Geodynamics -- Namibia -- Kaoko Belt
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5041 , http://hdl.handle.net/10962/d1007633
- Description: The ENE trending Brandberg West - Goantagab Sn-W belt is located in the Southern Kaoko Zone of the northern coastal branch of the Damara Orogen. The lithologies in this area are turbiditic and consist of three schist units separated by two marble horizons, all of which are correlated with the Swakop Group. The formations are intensely folded by at least three episodes of which the first two are coaxial and resulted in prominent, approximately N-S trending, structures. Sn and Sn-W mineralization predominantly occurs as vein and replacement type mineralization. Vein type mineralization occurs as Brandberg West, Frans Prospect, Gamigab Prospect and the Goantagab Mining Area. The vein type mineralization is accompanied by intense alteration, consisting of greisenization, sericitization, hematitization and carbonatization. Replacement-type, hematite-cassiterite mineralization, occurs in the Goantagab Mining area in the marble close to, or at the schist marble contact. Intense ferruginous alteration of the marbles in this area, is associated with veins, which terminate against, or cross cut the marble. A regional metal zonation, ranging from Sn-W mineralization with minor sulphides at Brandberg West to Sn-sulphide mineralization at Goantagab can be detected. This metal zonation is attributed to the distance of the mineral locality from the source area, with Goantagab representing a distal and Brandberg West a proximal position relative to the source area. Structural, mineralogical and geological features of the mineralization in this area suggest that processes of ore genesis may be related to anorogenic magmatism of Karoo age.
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'n Ondersoek na die vorm wat die opvoering in die primêre skool kan aanneem : met spesiale verwysing na geselekteerde primêre skole in die Westelike Provinsie
- Du Plessis, Philippus Lodewicus
- Authors: Du Plessis, Philippus Lodewicus
- Date: 1979
- Subjects: Drama in education
- Language: Afrikaans
- Type: Thesis , Masters , MA
- Identifier: vital:2128 , http://hdl.handle.net/10962/d1002030 , Drama in education
- Description: Watter vorm moet die opvoering in die primêre skool aanneem ? Die opvoering in die skool, en veral in die primêre skool word, veral sedert Peter Slade (1959 : 41-57 ens.) en Brian Way (1970 : 2-3 + 6-8 + 186- 189 + 268-269) gewaarsku het teen die gevare van die opvoering, deur baie beoefenaars van skooldrama afgekeur. Daar het in Engeland, Amerika en ook in Suid-Afrika tweespalt begin ontstaan tussen die aanhangers van die sogenaamde formeIe drama en die sogenaamde informele of vrye drama. Daar behoort nie so 'n tweespalt te wees indien die hele aangeleentheid reg benader word nie. (Heathcote soos opgeneem in Hodgson en Banham 1972 : 41). Daar word beoog om in hierdie studie ondersoek in te stel na die moontlike benaderingswyses asook die wenslikheid van die opvoering in die primêre skool. Die doel van hierdie studie is am opnuut te besin oor die waarde wat die skoolopvoering vir die kind kan hê. Ons durf, as opvoeders, die kind nie uitsluit van 'n aktiwiteit wat 'n bydrae tot sy totale ontwikkeling sou kon lewer nie. Daar word dus gehoop om tot 'n herwaardering van die skoolopvoering te kom wat waardevol sal kan wees in die opvoeding van die kind
- Full Text:
- Authors: Du Plessis, Philippus Lodewicus
- Date: 1979
- Subjects: Drama in education
- Language: Afrikaans
- Type: Thesis , Masters , MA
- Identifier: vital:2128 , http://hdl.handle.net/10962/d1002030 , Drama in education
- Description: Watter vorm moet die opvoering in die primêre skool aanneem ? Die opvoering in die skool, en veral in die primêre skool word, veral sedert Peter Slade (1959 : 41-57 ens.) en Brian Way (1970 : 2-3 + 6-8 + 186- 189 + 268-269) gewaarsku het teen die gevare van die opvoering, deur baie beoefenaars van skooldrama afgekeur. Daar het in Engeland, Amerika en ook in Suid-Afrika tweespalt begin ontstaan tussen die aanhangers van die sogenaamde formeIe drama en die sogenaamde informele of vrye drama. Daar behoort nie so 'n tweespalt te wees indien die hele aangeleentheid reg benader word nie. (Heathcote soos opgeneem in Hodgson en Banham 1972 : 41). Daar word beoog om in hierdie studie ondersoek in te stel na die moontlike benaderingswyses asook die wenslikheid van die opvoering in die primêre skool. Die doel van hierdie studie is am opnuut te besin oor die waarde wat die skoolopvoering vir die kind kan hê. Ons durf, as opvoeders, die kind nie uitsluit van 'n aktiwiteit wat 'n bydrae tot sy totale ontwikkeling sou kon lewer nie. Daar word dus gehoop om tot 'n herwaardering van die skoolopvoering te kom wat waardevol sal kan wees in die opvoeding van die kind
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The problem of authority in revelation
- Authors: Bax, Douglas S
- Date: 1958
- Subjects: Revelation , Revelation -- Biblical teaching , Revelation -- History of doctrines
- Language: English
- Type: Thesis , Bachelor , BDiv
- Identifier: vital:1283 , http://hdl.handle.net/10962/d1013468
- Description: From Preface: The problem of authority in religion can be stated as follows: what is the finally authoritative source and judge of religious truth? This was the fundamental question which Jesus Himself raised when He came to the Jews. It was the fundamental problem of the Reformation. It is also the fundamental problem that confronts the Church in our time. But it has never ceased to be the perennial question underlying all religious and philosophical thought.
- Full Text:
- Authors: Bax, Douglas S
- Date: 1958
- Subjects: Revelation , Revelation -- Biblical teaching , Revelation -- History of doctrines
- Language: English
- Type: Thesis , Bachelor , BDiv
- Identifier: vital:1283 , http://hdl.handle.net/10962/d1013468
- Description: From Preface: The problem of authority in religion can be stated as follows: what is the finally authoritative source and judge of religious truth? This was the fundamental question which Jesus Himself raised when He came to the Jews. It was the fundamental problem of the Reformation. It is also the fundamental problem that confronts the Church in our time. But it has never ceased to be the perennial question underlying all religious and philosophical thought.
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