Genetic characteristics of Human Immunodeficiency Virus-1, and deter-minants of late presentation for care and Diabetes mellitus amongst newly diagnosed Human Immunodeficiency Virus positive patients in the Eastern Cape, South Africa.
- Authors: Sogbanmu, Olufunso Oladipo
- Date: 2019
- Subjects: HIV infections
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/${Handle} , vital:40495
- Description: Phylogenies may help to characterize transmission pairs, enhance contact tracing and outbreak investigations, track the origin and spread of epidemics over place and time, and to identify patterns of onward Human Immunodeficiency-Virus (HIV) transmission among risk groups. If the pattern and evolution of HIV drug resistance can be mapped, this may influence the development of guidelines in the clinical management of HIV especially with issues relating to prevalence of primary drug resistance and its impact on outcomes of present antiretroviral treatment (ART) regimen in use and the ability to trace and track the development of drug resistant strains. The roll-out of the test and treat Programme for newly diagnosed HIV infected pa-tient, seeks to identify HIV infected individuals early and to prevent morbidity and mortality associated with the late presentation for HIV care. The determination of the magnitude of ‘late presentation’ and or ‘presentation with advanced HIV disease’ can be used in very diverse settings and for many purposes. It provides a unified way to define the problem, thereby targeting appropriate interventions to prevent the detrimental outcomes associated with late presentation to care. The subtle relationship between HIV and diabetes mellitus (DM) may also help in formulating better preventive programs to aid the control of non-communicable diseases such as DM. This cross-sectional study includes a purposive selection of 335 HIV positive patients attending the voluntary counselling and Testing (VCT) and HIV Counselling and Testing (HCT) centres and outpatient departments at Cecilia Makiwane Hospital and the HCT sites at the Buffalo District municipality community health centres, Eastern Cape Province, South Africa. Late or delayed presentation of HIV infection was defined as CD4 cell count beneath 350 cells/μL and/or patients presenting with an AIDS-defining event at the first follow-up regardless of the CD4 cell count. Chapter 1 provides the general introduction had an overview of the introduction to the study, the statement of the research problem, hypothesis, the aim and the objectives. xx Chapter 2 looked in-depth at the HIV, case definition, the latest epidemiology of HIV, the HIV genome, the life cycle of HIV, its diagnosis, the classes of antiretroviral drugs, development of drug resistance. Chapter 3 highlighted the prevalence of Transmitted Drug Resistance (TDR) with focus on the protease gene. RNA was extracted from blood samples of 72 newly diagnosed HIV-1 patients attending some HIV testing and counselling clinics from August 2016 to July 2017. Protease fragments were amplified with specific primers by RT-PCR followed by nested PCR. The amplified products were sequenced using the ABI 360 sequencer, edited with Geneious version 9.1.5 and translated into amino acid with BioEdit software. Drug related resistance mutation (DRMs) analysis was performed on all the protease sequences in accordance with the 2009 WHO list of surveillance drug resistance mutations by submitting the edited sequences to Stanford HIV drug interpretation programme and the international AIDS society-USA guidelines for query of drug resistance associated mutations while phylogenetic analysis was performed using MEGA 6 to allocate all viral sequences into subtypes. In the study, a total of 52/72 (71.1%) reliable HIV-1 protease sequences were obtained in which subtyping and drug resistance mutations were performed. Two (3.8%) major Protease resistance associated mutation (V82A/L and L90M) were observed while another polymorphism like L10F, T74S, Q58E, L10I/V and M46V were also identified. Phylogenetic analyses delineated all the sequences as HIV-1 subtype C. Chapter 4 describes the prevalence and the determinants of late presentation amongst newly diagnosed HIV positive individuals in the Eastern Cape. It indicates the extent of the prevalence of patients presenting to care and at what HIV stage they were assessing health care services since the inception of the ‘test and treat’ strategy. It is a cross-sectional study where a total of 335 newly diagnosed patients were recruited consecutively be-tween August 2016 and July 2017. Late presenter for HIV care was defined in accordance with the European Late Presenter Consensus working group as a patient who reports for care when the CD4 count is below 350 cells/μL and/or when there is an established Aids- xxi defining clinical condition, irrespective of CD4 count. Adjusted and unadjusted logistic regression analysis was used to examine the determinants of late HIV diagnosis. The study showed that 60% of patients were late presenters, with 35% presenting with advanced disease. The major determinants identified were being male and low level of education. This led to recommendations directed at ensuring programmes that targets men in identifying their HIV status and assess care at early stage to prevents the morbidity and mortality associated with delayed presentation. Also, it was recommended that effort should be made to improve access to education and also include HIV related topics into the educational curriculum. Chapter 5 aimed to describe the prevalence and determinants of DM amongst newly diagnosed HIV positive individuals. This is a cross-sectional study which recruited 335 patients between August 2016 and September 2017. Definition for diabetes mellitus was made based on the SEDMSA 2015 guideline of HBA1C of above 6.5%. Adjusted and unadjusted logistic regression analysis was used to examine the determinants of abnormal glycated haemoglobin. Findings showed the prevalence of DM at about 6% amongst newly diagnosed HIV positive individuals. This is similar to findings in other study within the country, but a bit lower than what was obtained in the developed countries. The role of older age (above 40 years) as predisposing factor to development of diabetes in newly diagnosed HIV positive individual was well noted and taken. This ensures that screening for DM should be targeted at elderly HIV positive individuals. The grey area of the appropriate mode of diagnostic test to use to diagnose HIV is still debatable, however, a combination of HBA1c and fasting blood sugar (FBS) may improve the diagnosis of DM in this population group. In chapter 6, the general conclusions, recommendations and future perspectives of the study are reflected.
- Full Text:
- Date Issued: 2019
- Authors: Sogbanmu, Olufunso Oladipo
- Date: 2019
- Subjects: HIV infections
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/${Handle} , vital:40495
- Description: Phylogenies may help to characterize transmission pairs, enhance contact tracing and outbreak investigations, track the origin and spread of epidemics over place and time, and to identify patterns of onward Human Immunodeficiency-Virus (HIV) transmission among risk groups. If the pattern and evolution of HIV drug resistance can be mapped, this may influence the development of guidelines in the clinical management of HIV especially with issues relating to prevalence of primary drug resistance and its impact on outcomes of present antiretroviral treatment (ART) regimen in use and the ability to trace and track the development of drug resistant strains. The roll-out of the test and treat Programme for newly diagnosed HIV infected pa-tient, seeks to identify HIV infected individuals early and to prevent morbidity and mortality associated with the late presentation for HIV care. The determination of the magnitude of ‘late presentation’ and or ‘presentation with advanced HIV disease’ can be used in very diverse settings and for many purposes. It provides a unified way to define the problem, thereby targeting appropriate interventions to prevent the detrimental outcomes associated with late presentation to care. The subtle relationship between HIV and diabetes mellitus (DM) may also help in formulating better preventive programs to aid the control of non-communicable diseases such as DM. This cross-sectional study includes a purposive selection of 335 HIV positive patients attending the voluntary counselling and Testing (VCT) and HIV Counselling and Testing (HCT) centres and outpatient departments at Cecilia Makiwane Hospital and the HCT sites at the Buffalo District municipality community health centres, Eastern Cape Province, South Africa. Late or delayed presentation of HIV infection was defined as CD4 cell count beneath 350 cells/μL and/or patients presenting with an AIDS-defining event at the first follow-up regardless of the CD4 cell count. Chapter 1 provides the general introduction had an overview of the introduction to the study, the statement of the research problem, hypothesis, the aim and the objectives. xx Chapter 2 looked in-depth at the HIV, case definition, the latest epidemiology of HIV, the HIV genome, the life cycle of HIV, its diagnosis, the classes of antiretroviral drugs, development of drug resistance. Chapter 3 highlighted the prevalence of Transmitted Drug Resistance (TDR) with focus on the protease gene. RNA was extracted from blood samples of 72 newly diagnosed HIV-1 patients attending some HIV testing and counselling clinics from August 2016 to July 2017. Protease fragments were amplified with specific primers by RT-PCR followed by nested PCR. The amplified products were sequenced using the ABI 360 sequencer, edited with Geneious version 9.1.5 and translated into amino acid with BioEdit software. Drug related resistance mutation (DRMs) analysis was performed on all the protease sequences in accordance with the 2009 WHO list of surveillance drug resistance mutations by submitting the edited sequences to Stanford HIV drug interpretation programme and the international AIDS society-USA guidelines for query of drug resistance associated mutations while phylogenetic analysis was performed using MEGA 6 to allocate all viral sequences into subtypes. In the study, a total of 52/72 (71.1%) reliable HIV-1 protease sequences were obtained in which subtyping and drug resistance mutations were performed. Two (3.8%) major Protease resistance associated mutation (V82A/L and L90M) were observed while another polymorphism like L10F, T74S, Q58E, L10I/V and M46V were also identified. Phylogenetic analyses delineated all the sequences as HIV-1 subtype C. Chapter 4 describes the prevalence and the determinants of late presentation amongst newly diagnosed HIV positive individuals in the Eastern Cape. It indicates the extent of the prevalence of patients presenting to care and at what HIV stage they were assessing health care services since the inception of the ‘test and treat’ strategy. It is a cross-sectional study where a total of 335 newly diagnosed patients were recruited consecutively be-tween August 2016 and July 2017. Late presenter for HIV care was defined in accordance with the European Late Presenter Consensus working group as a patient who reports for care when the CD4 count is below 350 cells/μL and/or when there is an established Aids- xxi defining clinical condition, irrespective of CD4 count. Adjusted and unadjusted logistic regression analysis was used to examine the determinants of late HIV diagnosis. The study showed that 60% of patients were late presenters, with 35% presenting with advanced disease. The major determinants identified were being male and low level of education. This led to recommendations directed at ensuring programmes that targets men in identifying their HIV status and assess care at early stage to prevents the morbidity and mortality associated with delayed presentation. Also, it was recommended that effort should be made to improve access to education and also include HIV related topics into the educational curriculum. Chapter 5 aimed to describe the prevalence and determinants of DM amongst newly diagnosed HIV positive individuals. This is a cross-sectional study which recruited 335 patients between August 2016 and September 2017. Definition for diabetes mellitus was made based on the SEDMSA 2015 guideline of HBA1C of above 6.5%. Adjusted and unadjusted logistic regression analysis was used to examine the determinants of abnormal glycated haemoglobin. Findings showed the prevalence of DM at about 6% amongst newly diagnosed HIV positive individuals. This is similar to findings in other study within the country, but a bit lower than what was obtained in the developed countries. The role of older age (above 40 years) as predisposing factor to development of diabetes in newly diagnosed HIV positive individual was well noted and taken. This ensures that screening for DM should be targeted at elderly HIV positive individuals. The grey area of the appropriate mode of diagnostic test to use to diagnose HIV is still debatable, however, a combination of HBA1c and fasting blood sugar (FBS) may improve the diagnosis of DM in this population group. In chapter 6, the general conclusions, recommendations and future perspectives of the study are reflected.
- Full Text:
- Date Issued: 2019
Teachers and learners’ perspectives towards English as a language of learning and teaching : a case of two selected secondary schools in the Amathole West Education District
- Osunkunle, Atinuke Oluwatoyin
- Authors: Osunkunle, Atinuke Oluwatoyin
- Date: 2019
- Subjects: English language -- Study and teaching Second language acquisition
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10353/16243 , vital:40702
- Description: The study aimed at examining teachers and learners’ perspectives towards English as a language of learning and teaching (LoLT), using two selected secondary schools in the Amathole West Education District as a case study and to see if English is indeed a language of choice among learners and teachers. The researcher employed an interpretative qualitative research paradigm and purposive non-probability sampling method was used to draw samples of participants for in-depth interviews and focus group discussions. The school principal and two teachers were purposively selected in each of the two schools, making a total of two school principals and four teachers that were interviewed. In addition, a member of the School Governing Body (SGB) was selected in each of the two schools and interviewed. The study also had one focus group discussion with learners in each of the two selected schools, making two focus groups in total. All the one-on-one in-depth interviews as well as the focus group discussions with the learners were recorded and then transcribed. The collected data was later analysed thematically to infer the meaning and present the findings. The findings revealed that most of the students in public schools are torn between two divides as they struggle with the use of English as a language of learning and teaching but seem to have no choice, as they all believed that the use of English is quite beneficial to them in many ways. Another critical finding is that some teachers find it difficult to teach in English because they do not have a good command of the language. This makes them to code-switch regularly using IsiXhosa along with English while they are supposed to teach in English. Thus, this affects the learners proper understanding of and grounding in the English language. The study also found out that the schools lack adequate support to ensure the effective use of English for learning and teaching. The study recommended that various support systems from the government are needed in order to ensure the acceptance and successful use of English as LoLT in South African public schools. In this regard, the participants assured that these would result in positive outcomes, as they would provide quality education through government support. The study concluded that English is the preferred LoLT by both teachers and learners, thus, it needs to be prioritised.
- Full Text:
- Date Issued: 2019
- Authors: Osunkunle, Atinuke Oluwatoyin
- Date: 2019
- Subjects: English language -- Study and teaching Second language acquisition
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10353/16243 , vital:40702
- Description: The study aimed at examining teachers and learners’ perspectives towards English as a language of learning and teaching (LoLT), using two selected secondary schools in the Amathole West Education District as a case study and to see if English is indeed a language of choice among learners and teachers. The researcher employed an interpretative qualitative research paradigm and purposive non-probability sampling method was used to draw samples of participants for in-depth interviews and focus group discussions. The school principal and two teachers were purposively selected in each of the two schools, making a total of two school principals and four teachers that were interviewed. In addition, a member of the School Governing Body (SGB) was selected in each of the two schools and interviewed. The study also had one focus group discussion with learners in each of the two selected schools, making two focus groups in total. All the one-on-one in-depth interviews as well as the focus group discussions with the learners were recorded and then transcribed. The collected data was later analysed thematically to infer the meaning and present the findings. The findings revealed that most of the students in public schools are torn between two divides as they struggle with the use of English as a language of learning and teaching but seem to have no choice, as they all believed that the use of English is quite beneficial to them in many ways. Another critical finding is that some teachers find it difficult to teach in English because they do not have a good command of the language. This makes them to code-switch regularly using IsiXhosa along with English while they are supposed to teach in English. Thus, this affects the learners proper understanding of and grounding in the English language. The study also found out that the schools lack adequate support to ensure the effective use of English for learning and teaching. The study recommended that various support systems from the government are needed in order to ensure the acceptance and successful use of English as LoLT in South African public schools. In this regard, the participants assured that these would result in positive outcomes, as they would provide quality education through government support. The study concluded that English is the preferred LoLT by both teachers and learners, thus, it needs to be prioritised.
- Full Text:
- Date Issued: 2019
The effective use of corporate social responsibility as a strategic marketing tool to achieve competitive advantage in the South African banking sector
- Authors: Sogoni, Shalene
- Date: 2019
- Subjects: Social responsibility of business , Business communication Mass media and business Marketing Banks and banking -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/44034 , vital:37094
- Description: The South African banking sector has increasingly grown, with the rise of new entrants in the market and a strong fintech focus, offering a completely digital banking service with products designed to improve the money management of clients. Competition within this sector has become rife, giving banks the option to compete by using traditional means or pursue alternative options. In the past, banks focused more on lowering costs, increasing sales, improve customer retention strategies and the development of superior digital products and services driven by new technology. However banking organisations also understand that is not enough. In order to survive in a highly competitive industry, firms will be have to diversify and follow alternative means outside of the standard traditional ways of doing banking. The business case for engaging in corporate social responsibility is clear and unavoidable as the scope and nature of the socio-economic problems within our communities persist, so has these societal problems become interdependent with the business environment. Therefore, executive managers and are now encouraged to become good corporate citizens, by becoming more socially responsible in the way it does its business. In other words, by strategically applying CSR, as a marketing tool, a company can be profitable, obtain a competitive advantage and simultaneously contribute towards making a sustainable difference in society. The intent of this study is to determine if corporate social responsibility is being effectively used as a strategic marketing tool to achieve competitive advantage in the South African banking sector. In addressing the main research question, and several other secondary objectives, this study seeks to enrich the discussion by presenting a theoretical review that demonstrates the relationship between several concepts, namely, corporate strategy, strategic marketing, corporate social responsibility and competitive advantage, interrelated in this study. The study employs a qualitative research approach by empirically conducting in-depth discussions with industry experts on the subject matter at hand, underpinned by academic literature. The study will justify the interdependencies of business and the society and explores the benefits of integrating CSR into the core strategy of business. The findings will be valuable to business executives, corporate social responsibility or marketing managers, academics and scholars who are trying to better understand the determinant’s of corporate social responsibility, strategic management and competitive advantage.
- Full Text:
- Date Issued: 2019
- Authors: Sogoni, Shalene
- Date: 2019
- Subjects: Social responsibility of business , Business communication Mass media and business Marketing Banks and banking -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/44034 , vital:37094
- Description: The South African banking sector has increasingly grown, with the rise of new entrants in the market and a strong fintech focus, offering a completely digital banking service with products designed to improve the money management of clients. Competition within this sector has become rife, giving banks the option to compete by using traditional means or pursue alternative options. In the past, banks focused more on lowering costs, increasing sales, improve customer retention strategies and the development of superior digital products and services driven by new technology. However banking organisations also understand that is not enough. In order to survive in a highly competitive industry, firms will be have to diversify and follow alternative means outside of the standard traditional ways of doing banking. The business case for engaging in corporate social responsibility is clear and unavoidable as the scope and nature of the socio-economic problems within our communities persist, so has these societal problems become interdependent with the business environment. Therefore, executive managers and are now encouraged to become good corporate citizens, by becoming more socially responsible in the way it does its business. In other words, by strategically applying CSR, as a marketing tool, a company can be profitable, obtain a competitive advantage and simultaneously contribute towards making a sustainable difference in society. The intent of this study is to determine if corporate social responsibility is being effectively used as a strategic marketing tool to achieve competitive advantage in the South African banking sector. In addressing the main research question, and several other secondary objectives, this study seeks to enrich the discussion by presenting a theoretical review that demonstrates the relationship between several concepts, namely, corporate strategy, strategic marketing, corporate social responsibility and competitive advantage, interrelated in this study. The study employs a qualitative research approach by empirically conducting in-depth discussions with industry experts on the subject matter at hand, underpinned by academic literature. The study will justify the interdependencies of business and the society and explores the benefits of integrating CSR into the core strategy of business. The findings will be valuable to business executives, corporate social responsibility or marketing managers, academics and scholars who are trying to better understand the determinant’s of corporate social responsibility, strategic management and competitive advantage.
- Full Text:
- Date Issued: 2019
A critical analysis of disaster risk management in local governance with reference to Sarah Baartman District Municipality
- Authors: Oosthuizen, Rene Cheryl
- Date: 2018
- Subjects: Disaster relief -- Citizen participation , Risk management -- South Africa -- Eastern Cape Local government -- South Africa -- Eastern Cape -- Citizen participation Rural development projects -- South Africa -- Eastern Cape Community development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/34487 , vital:33385
- Description: The devastation and destruction caused by natural and man-made disasters have become a global concern, particularly as such disasters affect the most vulnerable in society. The devastation they wreak frequently involves loss of lives and property. Globally, Disaster Management has moved in approach from reactive to proactive. Disaster management is now more than a field of study; it is the application of practices and principles which enable disasters to be managed both prior to and in the aftermath of their occurrence. Disaster risk management is the development approach to Disaster Management. The study addresses the integration of disaster risk management into integrated development planning at the local level in South Africa. The impact of disasters on social and economic development is of special interest. In many instances, resources that have been planned for development have to be diverted for response activities during disasters. Thus, development and disaster risk management are two sides of the same coin and should be dealt with in unison and not separately. There is also now widespread international acknowledgement for the idea of mainstreaming disaster risk management into development planning, particularly at the local level of government. The central argument of this study is that by integrating disaster risk management plans into integrated development plans at the local level, the risks faced by communities can be reduced. Risks can be even further reduced, and development enhanced when communities play an active role in disaster risk management. Within this context, the main objective of the study was to develop a model for integrating disaster risk management plans into integrated development plans at the local level. To achieve this key objective, the study used theoretical and empirical studies. The theoretical aspect focussed on international frameworks and national legislation for Disaster Management. Legislative requirements pertaining to the involvement of communities in integrated development planning were explored, as was the literature on asset-based community development. Empirical research complimented the theoretical research through the use of qualitative methods to collect data. This involved semi-structured interviews with eight government officials involved in provincial, district and municipal Disaster Management programmes, and focus group discussions with sixty ward committee members, so that community viewpoints would be included. The findings of the study reveal that the integration of disaster risk management plans into integrated development plans at the local level can greatly contribute towards reducing the risks faced by communities, especially high-risk communities. The study also revealed that by carefully considering and using community assets, local government could ameliorate the financial effects of Disaster Management and empower communities as first responders. The thesis gives an outline of a model that may be used by local government to integrate risks and community assets into an integrated development plan.
- Full Text:
- Date Issued: 2018
- Authors: Oosthuizen, Rene Cheryl
- Date: 2018
- Subjects: Disaster relief -- Citizen participation , Risk management -- South Africa -- Eastern Cape Local government -- South Africa -- Eastern Cape -- Citizen participation Rural development projects -- South Africa -- Eastern Cape Community development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/34487 , vital:33385
- Description: The devastation and destruction caused by natural and man-made disasters have become a global concern, particularly as such disasters affect the most vulnerable in society. The devastation they wreak frequently involves loss of lives and property. Globally, Disaster Management has moved in approach from reactive to proactive. Disaster management is now more than a field of study; it is the application of practices and principles which enable disasters to be managed both prior to and in the aftermath of their occurrence. Disaster risk management is the development approach to Disaster Management. The study addresses the integration of disaster risk management into integrated development planning at the local level in South Africa. The impact of disasters on social and economic development is of special interest. In many instances, resources that have been planned for development have to be diverted for response activities during disasters. Thus, development and disaster risk management are two sides of the same coin and should be dealt with in unison and not separately. There is also now widespread international acknowledgement for the idea of mainstreaming disaster risk management into development planning, particularly at the local level of government. The central argument of this study is that by integrating disaster risk management plans into integrated development plans at the local level, the risks faced by communities can be reduced. Risks can be even further reduced, and development enhanced when communities play an active role in disaster risk management. Within this context, the main objective of the study was to develop a model for integrating disaster risk management plans into integrated development plans at the local level. To achieve this key objective, the study used theoretical and empirical studies. The theoretical aspect focussed on international frameworks and national legislation for Disaster Management. Legislative requirements pertaining to the involvement of communities in integrated development planning were explored, as was the literature on asset-based community development. Empirical research complimented the theoretical research through the use of qualitative methods to collect data. This involved semi-structured interviews with eight government officials involved in provincial, district and municipal Disaster Management programmes, and focus group discussions with sixty ward committee members, so that community viewpoints would be included. The findings of the study reveal that the integration of disaster risk management plans into integrated development plans at the local level can greatly contribute towards reducing the risks faced by communities, especially high-risk communities. The study also revealed that by carefully considering and using community assets, local government could ameliorate the financial effects of Disaster Management and empower communities as first responders. The thesis gives an outline of a model that may be used by local government to integrate risks and community assets into an integrated development plan.
- Full Text:
- Date Issued: 2018
An investigation of experiences encountered by female adults living with HIV/AIDS and taking ARV treatment: the case of Ntselanzi location, Raymond Mhlaba municipality, Alice Eastern Cape
- Authors: Matumelo, Nobuhle
- Date: 2017
- Subjects: AIDS (Disease) -- South Africa -- Eastern Cape -- Prevention , HIV-positive persons -- South Africa -- Eastern Cape , HIV infections -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSoc
- Identifier: http://hdl.handle.net/10353/15012 , vital:40132
- Description: The study investigated the experiences encountered by female adults from Ntselamanzi living with Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) and using Anti-retroviral (ARV) treatment. The study used a qualitative approach as well as a case study design that was descriptive explorative and explanative. The sample size or the unit of analysis consisted of 29 participants who included 12 female adults living with HIV/AIDS and having used ARVs for a minimum of three months; six nurses directly serving the people living with HIV/AIDS (PLWHA); six family members catering for the infected members within their family setting; and five key informants that included a social worker, a community leader, a health promoter, a community developer, and an HIV co-ordinator situated within the community of Ntselamanzi. A non-probability sampling method was adopted, specifically incorporating both snowball and purposive sampling techniques to select the sample. Significantly, the study was led by the following objectives: (1) To explore the experiences of female adults living with HIV/AIDS in Ntselamanzi, (2) To establish the coping mechanisms adopted by the PLWHA (3) To determine the effects of coping challenges and the adherence to ARVs. The data was collected by means of face-toface in-depth interviews in tandem with focus group discussion (FGD); and it was analysed qualitatively using content thematic analysis. The findings of the study revealed that all female adults living with HIV/AIDS and using ARVs encountered innumerable challenges that impaired their coping. The findings also indicated that malfunctioning and interruption of PLWHA coping was influenced by social factors such as unemployment, high level of poverty, low educational levels, lack of information sharing programmes and dependency on social grants. Lastly, the support to PLWHA especially by family members was highly indicated in the study’s findings. The following recommendations emanated from the study: strengthening research on coping challenges of female adults using ARVs in rural areas; empowering and training more caregivers for PLWHA by the Health Department; more involvement of social workers in helping the PLWHA; more involvement of government in the HIV/AIDS campaign in rural settings; and government facilitation and support to the PLWHA to form and belong to support groups.
- Full Text:
- Date Issued: 2017
- Authors: Matumelo, Nobuhle
- Date: 2017
- Subjects: AIDS (Disease) -- South Africa -- Eastern Cape -- Prevention , HIV-positive persons -- South Africa -- Eastern Cape , HIV infections -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSoc
- Identifier: http://hdl.handle.net/10353/15012 , vital:40132
- Description: The study investigated the experiences encountered by female adults from Ntselamanzi living with Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) and using Anti-retroviral (ARV) treatment. The study used a qualitative approach as well as a case study design that was descriptive explorative and explanative. The sample size or the unit of analysis consisted of 29 participants who included 12 female adults living with HIV/AIDS and having used ARVs for a minimum of three months; six nurses directly serving the people living with HIV/AIDS (PLWHA); six family members catering for the infected members within their family setting; and five key informants that included a social worker, a community leader, a health promoter, a community developer, and an HIV co-ordinator situated within the community of Ntselamanzi. A non-probability sampling method was adopted, specifically incorporating both snowball and purposive sampling techniques to select the sample. Significantly, the study was led by the following objectives: (1) To explore the experiences of female adults living with HIV/AIDS in Ntselamanzi, (2) To establish the coping mechanisms adopted by the PLWHA (3) To determine the effects of coping challenges and the adherence to ARVs. The data was collected by means of face-toface in-depth interviews in tandem with focus group discussion (FGD); and it was analysed qualitatively using content thematic analysis. The findings of the study revealed that all female adults living with HIV/AIDS and using ARVs encountered innumerable challenges that impaired their coping. The findings also indicated that malfunctioning and interruption of PLWHA coping was influenced by social factors such as unemployment, high level of poverty, low educational levels, lack of information sharing programmes and dependency on social grants. Lastly, the support to PLWHA especially by family members was highly indicated in the study’s findings. The following recommendations emanated from the study: strengthening research on coping challenges of female adults using ARVs in rural areas; empowering and training more caregivers for PLWHA by the Health Department; more involvement of social workers in helping the PLWHA; more involvement of government in the HIV/AIDS campaign in rural settings; and government facilitation and support to the PLWHA to form and belong to support groups.
- Full Text:
- Date Issued: 2017
Combined in silico approaches towards the identification of novel malarial cysteine protease inhibitors
- Authors: Musyoka, Thommas Mutemi
- Date: 2017
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/4488 , vital:20679
- Description: Malaria an infectious disease caused by a group of parasitic organisms of the Plasmodium genus remains a severe public health problem in Africa, South America and parts of Asia. The leading causes for the persistence of malaria are the emergence of drug resistance to common antimalarial drugs, lack of effective vaccines and the inadequate control of mosquito vectors. Worryingly, accumulating evidence shows that the parasite has developed resistant to the current first-line treatment based on artemisinin. Hence, the identification and characterization of novel drug targets and drugs with unique mode of action remains an urgent priority. The successful sequencing and assembly of genomes from several Plasmodium species has opened an opportune window for the identification of new drug targets. Cysteine proteases are one of the major drug targets to be identified so far. The use of cysteine protease inhibitors coupled with gene manipulation studies has defined specific and putative roles of cysteine proteases which include hemoglobin degradation, erythrocyte rupture, immune evasion and erythrocyte invasion, steps which are central for the completion of the Plasmodium parasite life cycle. In an aim to discover potential novel antimalarials, this thesis focussed on falcipains (FPs), a group of four papain-like cysteine proteases from Plasmodium falciparum. Two of these enzymes, FP-2 and FP-3 are the major hemoglobinases and have been validated as drug targets. For the successful elimination of malaria, drugs must be safe and target both human and wild Plasmodium infective forms. Thus, an incipient aim was to identify protein homologs of these two proteases from other Plasmodium species and the host (human). From BLASTP analysis, up to 16 FP-2 and FP-3 homologs were identified (13 plasmodial proteases and 3 human cathepsins). Using in silico characterization approaches, the intra and inter group sequence, structural, phylogenetic and physicochemical differences were determined. To extend previous work (MSc student) involving docking studies on the identified proteins using known FP-2 and FP-3 inhibitors, a South African natural compound and its ZINC analogs, molecular dynamics and binding free energy studies were performed to determine the stabilities and quantification of the strength of interactions between the different protein-ligand complexes. From the results, key structural elements that regulate the binding and selectivity of non-peptidic compounds onto the different proteins were deciphered. Interaction fingerprints and energy decomposition analysis identified key residues and energetic terms that are central for effective ligand binding. This research presents novel insight essential for the structure-based molecular drug design of more potent antimalarial drugs.
- Full Text:
- Date Issued: 2017
- Authors: Musyoka, Thommas Mutemi
- Date: 2017
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/4488 , vital:20679
- Description: Malaria an infectious disease caused by a group of parasitic organisms of the Plasmodium genus remains a severe public health problem in Africa, South America and parts of Asia. The leading causes for the persistence of malaria are the emergence of drug resistance to common antimalarial drugs, lack of effective vaccines and the inadequate control of mosquito vectors. Worryingly, accumulating evidence shows that the parasite has developed resistant to the current first-line treatment based on artemisinin. Hence, the identification and characterization of novel drug targets and drugs with unique mode of action remains an urgent priority. The successful sequencing and assembly of genomes from several Plasmodium species has opened an opportune window for the identification of new drug targets. Cysteine proteases are one of the major drug targets to be identified so far. The use of cysteine protease inhibitors coupled with gene manipulation studies has defined specific and putative roles of cysteine proteases which include hemoglobin degradation, erythrocyte rupture, immune evasion and erythrocyte invasion, steps which are central for the completion of the Plasmodium parasite life cycle. In an aim to discover potential novel antimalarials, this thesis focussed on falcipains (FPs), a group of four papain-like cysteine proteases from Plasmodium falciparum. Two of these enzymes, FP-2 and FP-3 are the major hemoglobinases and have been validated as drug targets. For the successful elimination of malaria, drugs must be safe and target both human and wild Plasmodium infective forms. Thus, an incipient aim was to identify protein homologs of these two proteases from other Plasmodium species and the host (human). From BLASTP analysis, up to 16 FP-2 and FP-3 homologs were identified (13 plasmodial proteases and 3 human cathepsins). Using in silico characterization approaches, the intra and inter group sequence, structural, phylogenetic and physicochemical differences were determined. To extend previous work (MSc student) involving docking studies on the identified proteins using known FP-2 and FP-3 inhibitors, a South African natural compound and its ZINC analogs, molecular dynamics and binding free energy studies were performed to determine the stabilities and quantification of the strength of interactions between the different protein-ligand complexes. From the results, key structural elements that regulate the binding and selectivity of non-peptidic compounds onto the different proteins were deciphered. Interaction fingerprints and energy decomposition analysis identified key residues and energetic terms that are central for effective ligand binding. This research presents novel insight essential for the structure-based molecular drug design of more potent antimalarial drugs.
- Full Text:
- Date Issued: 2017
Investigating how Grade 10 Physical Science teachers help learners to make sense of concepts of electromagnetism using easily accessible materials in under-resourced schools
- Authors: Samuel, Paulo
- Date: 2017
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/8143 , vital:21359
- Description: This study sought to explore teachers’ perceptions and experiences of using easily accessible materials and how they might collaboratively develop learning and teaching support materials using easily accessible materials. The study explored three aspects. Firstly, the views, experiences and factors which influence grade 10 Physical Science teachers’ perceptions and experiences of teaching the topic of electromagnetism. Secondly, to find out what teachers can do to improve teaching and learning of electromagnetism in grade 10 Physical Science using easily accessible materials. Thirdly, to look at what enables or constrains grade 10 Physical Science teachers in under-resourced schools when dealing with electromagnetism, from using easily accessible materials. A qualitative method approach was adopted, underpinned by an interpretive paradigm but using some quantitative methods as well. Within the interpretive paradigm a case study approach was used. The study was carried out in Swakopmund and Gobabis education circuits of the Erongo and Omaheke Regions respectively. Data were collected using questionnaires, lesson observations and stimulated-recall interviews. The data obtained were validated in two ways, firstly, by triangulation from different data gathering techniques, and secondly, validation was done by member checking of the transcripts. To make meaning from the data generated, Vygotsky’s (1978) socio-cultural theory was used as a lens to analyse the data. The quantitative data generated were presented in figures, tables; whereas the qualitative data were coded inductively into descriptive texts to make meaning. It was found that teachers’s perceptions and experiences are that the topic of electromagnetism is quite challenging. Teachers reported that their learners find it difficult to comprehend phenomena associated with electromagnetism, thus making it difficult for their learners to grasp concepts associated with it. Lack of resources to do practical activities in the topic of electromagnetism was found to be a major contributing factor to teaching and learning of this topic. The use of easily accessible materials among teachers was found to be very limited. Easily accessible locally sourced materials were found to have the potential to enable grade 10 Physical Science teachers to help learners to make sense of concepts of electromagnetism in under-resourced schools. In light of the above findings, the study recommends that science teachers should make use of easily accessible materials which can minimise their dependence on standard laboratory equipment which is unaffordable anyway by most schools.
- Full Text:
- Date Issued: 2017
- Authors: Samuel, Paulo
- Date: 2017
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/8143 , vital:21359
- Description: This study sought to explore teachers’ perceptions and experiences of using easily accessible materials and how they might collaboratively develop learning and teaching support materials using easily accessible materials. The study explored three aspects. Firstly, the views, experiences and factors which influence grade 10 Physical Science teachers’ perceptions and experiences of teaching the topic of electromagnetism. Secondly, to find out what teachers can do to improve teaching and learning of electromagnetism in grade 10 Physical Science using easily accessible materials. Thirdly, to look at what enables or constrains grade 10 Physical Science teachers in under-resourced schools when dealing with electromagnetism, from using easily accessible materials. A qualitative method approach was adopted, underpinned by an interpretive paradigm but using some quantitative methods as well. Within the interpretive paradigm a case study approach was used. The study was carried out in Swakopmund and Gobabis education circuits of the Erongo and Omaheke Regions respectively. Data were collected using questionnaires, lesson observations and stimulated-recall interviews. The data obtained were validated in two ways, firstly, by triangulation from different data gathering techniques, and secondly, validation was done by member checking of the transcripts. To make meaning from the data generated, Vygotsky’s (1978) socio-cultural theory was used as a lens to analyse the data. The quantitative data generated were presented in figures, tables; whereas the qualitative data were coded inductively into descriptive texts to make meaning. It was found that teachers’s perceptions and experiences are that the topic of electromagnetism is quite challenging. Teachers reported that their learners find it difficult to comprehend phenomena associated with electromagnetism, thus making it difficult for their learners to grasp concepts associated with it. Lack of resources to do practical activities in the topic of electromagnetism was found to be a major contributing factor to teaching and learning of this topic. The use of easily accessible materials among teachers was found to be very limited. Easily accessible locally sourced materials were found to have the potential to enable grade 10 Physical Science teachers to help learners to make sense of concepts of electromagnetism in under-resourced schools. In light of the above findings, the study recommends that science teachers should make use of easily accessible materials which can minimise their dependence on standard laboratory equipment which is unaffordable anyway by most schools.
- Full Text:
- Date Issued: 2017
Synthesis and photophysical studies of crown ether-bodipy dyes and the fabrication of bodipy embedded fluorescent nanofibers
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
- Full Text:
- Date Issued: 2017
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
- Full Text:
- Date Issued: 2017
Investigating teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in 'Grades 5-7': a Namibian case study
- Authors: Iiyambo,Julia
- Date: 2016
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/1296 , vital:20044
- Description: This study investigated teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in ‘grades 5 – 7’. Three teachers were involved in the study and the main goal was to explore how teachers might work with the additional tools of multiple representations to improve the teaching of fractions for conceptual understanding. Different types of multiple representations such as written mathematical symbols, descriptive written words, pictorial representations, manipulations, concrete reality, oral representations, and experience-based representations and videos or power point presentations were examined. This investigation was carried out through a focus group workshop developed by the researcher and though observations of fraction teaching which took place in schools. The research focused on the teachers working to develop their use of multiple representations to teach fractions and how they implemented what they learned in the workshop into their own classroom teaching. This study was conducted using a qualitative case study design and was oriented in the interpretive paradigm. The three participating teachers in the focus group workshop were observed and interviewed individually. The purpose of observing teaching before the workshop was to observe how the selected teachers taught fractions and in particular to observe which types of representations they used and how these were used to enhance the conceptual understanding of the learners. Post teaching took place after the focus group workshop and the different multiple representations which were used in different lessons were observed and analyzed. The purpose of the interview was to gain an understanding of the teachers’ views of using multiple representations when teaching fractions for conceptual understanding. The data showed that teachers who participated in the focus group workshop worked positively to develop their use of multiple representations to teach fractions. They made sense of fractions and were able to look at representations in different ways to develop the meaning and concepts of fractions. Teachers developed an understanding of working with multiple representations and were able to make connections among concepts and the use of concrete representations. Teachers also developed their lesson plans effectively to involve a variety of teaching methods and multiple representations, despite the limited time available to them. Moreover, teachers used different modes of representation to improve learner engagement in learning activities. Lastly, teachers used multiple representations to teach in ways that improved the learners’ conception of fractions. On the basis of this research, it can be concluded that in-service workshops for teachers on the integration of multiple representative tools in the teaching of ‘Grades 5 – 7’ fractions could provide a valuable contribution to further developing the teaching of fractions in schools.
- Full Text:
- Date Issued: 2016
- Authors: Iiyambo,Julia
- Date: 2016
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/1296 , vital:20044
- Description: This study investigated teachers’ experiences of using multiple representations to teach fractions for conceptual understanding in ‘grades 5 – 7’. Three teachers were involved in the study and the main goal was to explore how teachers might work with the additional tools of multiple representations to improve the teaching of fractions for conceptual understanding. Different types of multiple representations such as written mathematical symbols, descriptive written words, pictorial representations, manipulations, concrete reality, oral representations, and experience-based representations and videos or power point presentations were examined. This investigation was carried out through a focus group workshop developed by the researcher and though observations of fraction teaching which took place in schools. The research focused on the teachers working to develop their use of multiple representations to teach fractions and how they implemented what they learned in the workshop into their own classroom teaching. This study was conducted using a qualitative case study design and was oriented in the interpretive paradigm. The three participating teachers in the focus group workshop were observed and interviewed individually. The purpose of observing teaching before the workshop was to observe how the selected teachers taught fractions and in particular to observe which types of representations they used and how these were used to enhance the conceptual understanding of the learners. Post teaching took place after the focus group workshop and the different multiple representations which were used in different lessons were observed and analyzed. The purpose of the interview was to gain an understanding of the teachers’ views of using multiple representations when teaching fractions for conceptual understanding. The data showed that teachers who participated in the focus group workshop worked positively to develop their use of multiple representations to teach fractions. They made sense of fractions and were able to look at representations in different ways to develop the meaning and concepts of fractions. Teachers developed an understanding of working with multiple representations and were able to make connections among concepts and the use of concrete representations. Teachers also developed their lesson plans effectively to involve a variety of teaching methods and multiple representations, despite the limited time available to them. Moreover, teachers used different modes of representation to improve learner engagement in learning activities. Lastly, teachers used multiple representations to teach in ways that improved the learners’ conception of fractions. On the basis of this research, it can be concluded that in-service workshops for teachers on the integration of multiple representative tools in the teaching of ‘Grades 5 – 7’ fractions could provide a valuable contribution to further developing the teaching of fractions in schools.
- Full Text:
- Date Issued: 2016
The potential economic implications of black locust (Robinia pseudoacacia l.) on agricultural production in South Africa
- Authors: Humphrey, Luke
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4069 , vital:20599
- Description: Black Locust (Robinia pseudoacacia L.) is an invasive deciduous, strongly suckering, broad- leaved tree that has the potential to be widely distributed across a large portion of South Africa. Robinia pseudoacacia has invaded all nine of South African provinces, with large infestations found in the Eastern Cape, Kwa Zulu-Natal, Free State and Gauteng provinces. The invasive tree has the potential to spread into livestock grazing lands in South Africa. Because R. pseudoacacia has the ability to spread and thrive in a variety of habitats and resists control, the distribution of the invasive tree into grazing land poses a problem for landowners. The potential economic impacts of R. pseudoacacia on agricultural production stem from the trees ability to reduce the carrying capacity of livestock. This study estimated the potential economic implications of R. pseudoacacia on agricultural production in South Africa, specifically looking at the livestock sector. The prevalence of R. pseudoacacia potential distribution was calculated by using a maximum-entropy predictive habitat model, MAXENT. The distribution of livestock, based on grazing capacity (ha/LSU), in South Africa was then determined. The potential direct economic impacts were estimated by assessing the impact of the potential distribution of R. pseudoacacia on the carrying capacity of livestock. The results showed that an infestation of R. pseudoacacia has the potential to reduce the gross margin in the livestock sector by between approximately R130 million and R961 million, dependent on the probability of invasion. Therefore, the potential invasion of R. pseudoacacia can have detrimental effects on the livestock sector in South Africa. The potential high levels of foregone income and business activity found in this study reaffirm the need to devote resources to develop a viable, economical and effective control method, such as biological control.
- Full Text:
- Date Issued: 2016
- Authors: Humphrey, Luke
- Date: 2016
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4069 , vital:20599
- Description: Black Locust (Robinia pseudoacacia L.) is an invasive deciduous, strongly suckering, broad- leaved tree that has the potential to be widely distributed across a large portion of South Africa. Robinia pseudoacacia has invaded all nine of South African provinces, with large infestations found in the Eastern Cape, Kwa Zulu-Natal, Free State and Gauteng provinces. The invasive tree has the potential to spread into livestock grazing lands in South Africa. Because R. pseudoacacia has the ability to spread and thrive in a variety of habitats and resists control, the distribution of the invasive tree into grazing land poses a problem for landowners. The potential economic impacts of R. pseudoacacia on agricultural production stem from the trees ability to reduce the carrying capacity of livestock. This study estimated the potential economic implications of R. pseudoacacia on agricultural production in South Africa, specifically looking at the livestock sector. The prevalence of R. pseudoacacia potential distribution was calculated by using a maximum-entropy predictive habitat model, MAXENT. The distribution of livestock, based on grazing capacity (ha/LSU), in South Africa was then determined. The potential direct economic impacts were estimated by assessing the impact of the potential distribution of R. pseudoacacia on the carrying capacity of livestock. The results showed that an infestation of R. pseudoacacia has the potential to reduce the gross margin in the livestock sector by between approximately R130 million and R961 million, dependent on the probability of invasion. Therefore, the potential invasion of R. pseudoacacia can have detrimental effects on the livestock sector in South Africa. The potential high levels of foregone income and business activity found in this study reaffirm the need to devote resources to develop a viable, economical and effective control method, such as biological control.
- Full Text:
- Date Issued: 2016
Vocational curriculum report 191(NATED) as a curriculum: a case study of three Eastern Cape TVET Colleges
- Authors: Sixabayi, Siyabonga Prince
- Date: 2016
- Subjects: Vocational education -- Curricula -- South Africa -- Eastern Cape Curriculum planning -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10353/5126 , vital:29089
- Description: This study aimed to investigate if there are any possible gaps in the offering Vocational Curriculum Report 191, in terms of knowledge, skills and link to the world of work. This study was a case study of three Technical and Vocational Education and Training Colleges that offer Vocational Curriculum Report 191, and it was geographically limited to the province of the Eastern Cape. The five main findings from this study were that firstly, the curriculum offers theory without practice. Secondly, there is a mismatch between what is offered as curriculum at Technical and Vocational Education and Training Colleges and what the labour market wants. Thirdly, lecturers do not have the practical exposure that relates to their fields of study. Fourthly, Vocational Curriculum Report 191 does not promote self-employment of its students and lastly, the curriculum is outdated and does not comply with the criteria of current employment opportunities. The study recommends that the curriculum be reviewed and revised. Technical and Vocational Education and Training colleges need to have in site practice facilities to cater for the practical application of theoretical knowledge of students. Partnerships between Technical and Vocational Education and Training Colleges, the labour market and Sector Education and Training Authorities are strongly recommended in this study.
- Full Text:
- Date Issued: 2016
- Authors: Sixabayi, Siyabonga Prince
- Date: 2016
- Subjects: Vocational education -- Curricula -- South Africa -- Eastern Cape Curriculum planning -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10353/5126 , vital:29089
- Description: This study aimed to investigate if there are any possible gaps in the offering Vocational Curriculum Report 191, in terms of knowledge, skills and link to the world of work. This study was a case study of three Technical and Vocational Education and Training Colleges that offer Vocational Curriculum Report 191, and it was geographically limited to the province of the Eastern Cape. The five main findings from this study were that firstly, the curriculum offers theory without practice. Secondly, there is a mismatch between what is offered as curriculum at Technical and Vocational Education and Training Colleges and what the labour market wants. Thirdly, lecturers do not have the practical exposure that relates to their fields of study. Fourthly, Vocational Curriculum Report 191 does not promote self-employment of its students and lastly, the curriculum is outdated and does not comply with the criteria of current employment opportunities. The study recommends that the curriculum be reviewed and revised. Technical and Vocational Education and Training colleges need to have in site practice facilities to cater for the practical application of theoretical knowledge of students. Partnerships between Technical and Vocational Education and Training Colleges, the labour market and Sector Education and Training Authorities are strongly recommended in this study.
- Full Text:
- Date Issued: 2016
An exploration of the school nutrition programme's potential to catalyse community-based environmental learning : a case study of a rural Eastern Cape school
- Authors: Tshabeni, Veliswa
- Date: 2015
- Subjects: National School Nutrition Programme (South Africa) , School children -- Food -- South Africa -- Eastern Cape , Children -- Nutrition -- South Africa -- Eastern Cape , Environmental education -- South Africa -- Eastern Cape , Social learning -- South Africa -- Eastern Cape , Food security -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Poverty -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2063 , http://hdl.handle.net/10962/d1020306
- Description: The purpose of this study was to explore the extent to which a School Nutrition Programme can catalyse community-based environmental learning and promote food security in the school and the community. This is an interpretive case study of a junior secondary school in the rural Eastern Cape province of South Africa. The school is located in an area characterised by high levels of poverty and under-nutrition. The school’s food garden, a central focus of this study, contributes to the School Nutrition Programme, which falls under the National School Nutrition Programme (NSNP). The aim of the NSNP is to alleviate poverty in public schools. This case study was conducted by means of questionnaires, semi-structured interviews, and document analysis and field observations. The data set was analysed, firstly, to ascertain if the School Nutrition Programme functions as a community of practise (Wenger, 1998). Thereafter, the data set was analysed to identify the knowledge related to food security and environmental sustainability that is learned and shared in the School Nutrition Programme, and also how such learning took place. The study found that the School’s Nutrition Programme was indeed operating as a community of practice and that it created a platform for sharing explicit and tacit knowledge and skills related to food security and environmental sustainability. The case study also revealed the contextual and experience-based nature of knowledge related to food cultivation.
- Full Text:
- Date Issued: 2015
- Authors: Tshabeni, Veliswa
- Date: 2015
- Subjects: National School Nutrition Programme (South Africa) , School children -- Food -- South Africa -- Eastern Cape , Children -- Nutrition -- South Africa -- Eastern Cape , Environmental education -- South Africa -- Eastern Cape , Social learning -- South Africa -- Eastern Cape , Food security -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Poverty -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:2063 , http://hdl.handle.net/10962/d1020306
- Description: The purpose of this study was to explore the extent to which a School Nutrition Programme can catalyse community-based environmental learning and promote food security in the school and the community. This is an interpretive case study of a junior secondary school in the rural Eastern Cape province of South Africa. The school is located in an area characterised by high levels of poverty and under-nutrition. The school’s food garden, a central focus of this study, contributes to the School Nutrition Programme, which falls under the National School Nutrition Programme (NSNP). The aim of the NSNP is to alleviate poverty in public schools. This case study was conducted by means of questionnaires, semi-structured interviews, and document analysis and field observations. The data set was analysed, firstly, to ascertain if the School Nutrition Programme functions as a community of practise (Wenger, 1998). Thereafter, the data set was analysed to identify the knowledge related to food security and environmental sustainability that is learned and shared in the School Nutrition Programme, and also how such learning took place. The study found that the School’s Nutrition Programme was indeed operating as a community of practice and that it created a platform for sharing explicit and tacit knowledge and skills related to food security and environmental sustainability. The case study also revealed the contextual and experience-based nature of knowledge related to food cultivation.
- Full Text:
- Date Issued: 2015
Risky sexual behaviour in child headed families: A case study of Qora village, Idutywa, Eastern Cape Province
- Authors: Ntutumbo, Nyameka
- Date: 2015
- Subjects: Teenagers -- Sexual behavior -- South Africa -- Eastern Cape Orphans -- Sexual behavior -- South Africa -- Eastern Cape Risk-taking (Psychology)
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10353/5213 , vital:29113
- Description: The study considered the prevalence of risky sexual behaviour in child headed families that usually affects the adolescents in South Africa. This study aimed at exploring the prevalence of risky sexual behaviour in child headed families, determining the causal factors of sexual promiscuous behaviour and effects of promiscuity. The area of investigation was Qora Village which is in a small town called Idutywa, Eastern Cape. This is an area that is characterised by poverty, illiteracy and unemployment. The sample was comprised of 50 participants and the study was conducted in two phases using mixed methods approach. Social exchange theory underpinned the study. Findings highlighted that these child headed adolescents had a role of caregivers and due to poverty they practiced risky sexual behaviour to bridge the economic gap. Furthermore, teenagers living in child headed families were likely to engage in risky sexual behaviour with people who are older than them; others are forced and coerced; while others perceive such act as a better option to bridge the economic gap that existed within their family backgrounds.
- Full Text:
- Date Issued: 2015
- Authors: Ntutumbo, Nyameka
- Date: 2015
- Subjects: Teenagers -- Sexual behavior -- South Africa -- Eastern Cape Orphans -- Sexual behavior -- South Africa -- Eastern Cape Risk-taking (Psychology)
- Language: English
- Type: Thesis , Masters , Degree
- Identifier: http://hdl.handle.net/10353/5213 , vital:29113
- Description: The study considered the prevalence of risky sexual behaviour in child headed families that usually affects the adolescents in South Africa. This study aimed at exploring the prevalence of risky sexual behaviour in child headed families, determining the causal factors of sexual promiscuous behaviour and effects of promiscuity. The area of investigation was Qora Village which is in a small town called Idutywa, Eastern Cape. This is an area that is characterised by poverty, illiteracy and unemployment. The sample was comprised of 50 participants and the study was conducted in two phases using mixed methods approach. Social exchange theory underpinned the study. Findings highlighted that these child headed adolescents had a role of caregivers and due to poverty they practiced risky sexual behaviour to bridge the economic gap. Furthermore, teenagers living in child headed families were likely to engage in risky sexual behaviour with people who are older than them; others are forced and coerced; while others perceive such act as a better option to bridge the economic gap that existed within their family backgrounds.
- Full Text:
- Date Issued: 2015
A discussion and comparison of company legislation and tax legislation in South Africa, in relation to amalgamations and mergers
- Authors: Sloane, Justin
- Date: 2014
- Subjects: Corporation law -- South Africa , Taxation -- Law and legislation -- South Africa , Consolidation and merger of corporations -- South Africa , Income tax -- South Africa , Capital gains tax -- South Africa , Value-added tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:908 , http://hdl.handle.net/10962/d1013028
- Description: In his 2012 Budget Review, the Minister of Finance, Pravin Gordhan acknowledged that the introduction of the "new" Companies Act had given rise to certain anomalies in relation to tax and subsequently announced that the South African government would undertake to review the nature of company mergers, acquisitions and other restructurings with the view of possibly amending the Income Tax Act and/or the "new" Companies Act, to bring the two legislations in line with one another. These anomalies give rise to the present research. The literature reviewed in the present research revealed and identified the inconsistencies that exist between the "new" Companies Act, 71 of 2008 and the Income Tax Act, 58 of 1962, specifically the inconsistencies that exist in respect of the newly introduced amalgamation or merger provisions as set out in the "new" Companies Act. Moreover, this research was undertaken to identify the potential tax implications insofar as they relate to amalgamation transactions and, in particular, the potential tax implications where such transactions, because of the anomalies, fall outside the ambit section 44 of the Income Tax Act, which would in normal circumstances provide for tax "rollover relief". In this regard, the present research identified the possible income tax, capital gains tax, value-added tax, transfer duty tax and securities transfer tax affected by an amalgamation transaction, on the assumption that the "rollover relief" in section 44 of the Income Tax Act does not apply.
- Full Text:
- Date Issued: 2014
- Authors: Sloane, Justin
- Date: 2014
- Subjects: Corporation law -- South Africa , Taxation -- Law and legislation -- South Africa , Consolidation and merger of corporations -- South Africa , Income tax -- South Africa , Capital gains tax -- South Africa , Value-added tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:908 , http://hdl.handle.net/10962/d1013028
- Description: In his 2012 Budget Review, the Minister of Finance, Pravin Gordhan acknowledged that the introduction of the "new" Companies Act had given rise to certain anomalies in relation to tax and subsequently announced that the South African government would undertake to review the nature of company mergers, acquisitions and other restructurings with the view of possibly amending the Income Tax Act and/or the "new" Companies Act, to bring the two legislations in line with one another. These anomalies give rise to the present research. The literature reviewed in the present research revealed and identified the inconsistencies that exist between the "new" Companies Act, 71 of 2008 and the Income Tax Act, 58 of 1962, specifically the inconsistencies that exist in respect of the newly introduced amalgamation or merger provisions as set out in the "new" Companies Act. Moreover, this research was undertaken to identify the potential tax implications insofar as they relate to amalgamation transactions and, in particular, the potential tax implications where such transactions, because of the anomalies, fall outside the ambit section 44 of the Income Tax Act, which would in normal circumstances provide for tax "rollover relief". In this regard, the present research identified the possible income tax, capital gains tax, value-added tax, transfer duty tax and securities transfer tax affected by an amalgamation transaction, on the assumption that the "rollover relief" in section 44 of the Income Tax Act does not apply.
- Full Text:
- Date Issued: 2014
Intimacy, sex and sexuality : the experiences of vertically-infected HIV-positive adolescents
- Authors: Smaill, Lindsay Ann
- Date: 2014
- Subjects: Teenagers -- Sexual behavior , HIV-positive youth -- South Africa -- Eastern Cape , HIV infections -- Social aspects -- South Africa -- Eastern Cape , HIV infections -- Transmission -- South Africa -- Eastern Cape , Teenagers -- Diseases -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3225 , http://hdl.handle.net/10962/d1013026
- Description: This research explores the lived experience of being a vertically or prenatally-infected HIV-positive adolescent. It looks specifically at how the participants experience intimacy, sex and sexuality. HIV/AIDS remains a global pandemic and vertically-infected adolescents are a growing new demographic. However, there is a poverty of research, and therefore interventions and support, for this demographic. This qualitative research conducted six individual, in-depth, semi-structured, psychoanalytic research interviews with three participants. The interviews were structured around projective drawings that the participants did in the course of each interview. The interviews were transcribed and analysed using psychodynamic object relations theory and organised through interpretative phenomenological analysis. Every effort was made to ensure that the research was conducted ethically and validly. The analysis found that the participants' experience of intimacy has resulted in a self that is constantly under threat. This in turn has negatively impacted on the participants' experience of sex and sexuality. The implication of this research is that more in-depth research needs to be done into this demographic so that better interventions and support may be offered.
- Full Text:
- Date Issued: 2014
- Authors: Smaill, Lindsay Ann
- Date: 2014
- Subjects: Teenagers -- Sexual behavior , HIV-positive youth -- South Africa -- Eastern Cape , HIV infections -- Social aspects -- South Africa -- Eastern Cape , HIV infections -- Transmission -- South Africa -- Eastern Cape , Teenagers -- Diseases -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3225 , http://hdl.handle.net/10962/d1013026
- Description: This research explores the lived experience of being a vertically or prenatally-infected HIV-positive adolescent. It looks specifically at how the participants experience intimacy, sex and sexuality. HIV/AIDS remains a global pandemic and vertically-infected adolescents are a growing new demographic. However, there is a poverty of research, and therefore interventions and support, for this demographic. This qualitative research conducted six individual, in-depth, semi-structured, psychoanalytic research interviews with three participants. The interviews were structured around projective drawings that the participants did in the course of each interview. The interviews were transcribed and analysed using psychodynamic object relations theory and organised through interpretative phenomenological analysis. Every effort was made to ensure that the research was conducted ethically and validly. The analysis found that the participants' experience of intimacy has resulted in a self that is constantly under threat. This in turn has negatively impacted on the participants' experience of sex and sexuality. The implication of this research is that more in-depth research needs to be done into this demographic so that better interventions and support may be offered.
- Full Text:
- Date Issued: 2014
Valuation of banks in emerging markets: an exploratory study
- Authors: Sabilika, Keith
- Date: 2014
- Subjects: Banks and banking -- Valuation , Banks and banking -- Valuation -- Developing countries , Discounted cash flow , Capital assets pricing model , Capital -- Developing countries
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1200 , http://hdl.handle.net/10962/d1013057
- Description: Practitioners and academics in emerging markets are yet to agree on how best they can value companies in emerging markets. In contrast, academics and practitioners in developed markets seem to agree on mainstream valuation practices (Bruner, Eades, Harris and Haggins, 1998; Graham and Harvey, 2001). This study was therefore aimed at achieving such consensus with particular attention being paid to the emerging market banks. Emerging market banks are by no means small and are growing fast. Furthermore, these banks are currently involved in lots of cutting age economic activities such as mergers and acquisitions (M&A), joint ventures and strategic alliances which require sound valuation practices that are based on empirical evidence. The primary purpose of this research was to establish consensus of opinion among experts with regard to the valuation of banks in emerging markets. To achieve the purpose of this study the Delphi technique, which is a structured survey method that relies on a panel of experts to answer questionnaires in two or more Delphi rounds, was used to gather data and develop consensus among experts (Kalaian and Kasim, 2012). The main findings in this study pertain to aspects concerning the type of analysis considered by experts when analysing the performance of banks, how experts compare the discounted cash flow (DCF) approach to multiples valuation approach, the challenges encountered by experts when valuing banks in emerging markets, and how experts compute the cost of capital for banks in emerging markets. The main findings of this study can be summarised as follows: ∙ When analyzing the performance of banks, it is essential to conduct a bank-specific, industry and macroeconomic analysis; ∙ When estimating the future performance of banks, the time series analysis and an explicit forecast period of between 4-10 years may be used; ∙ When estimating the terminal value for banks in emerging markets, the perpetuity with growth is used; ∙ When computing the value for banks, the DCF valuation approach (equity DCF and DDM valuation models) are used as primary valuation methods and the relative valuation approach (P/E and P/BV ratio) are used as secondary valuation methods; ∙ The DCF valuation approach is considered as more accurate and popular when valuing banks in emerging markets; and ∙ When estimating the cost of equity, the capital asset pricing model (CAPM) is used.
- Full Text:
- Date Issued: 2014
- Authors: Sabilika, Keith
- Date: 2014
- Subjects: Banks and banking -- Valuation , Banks and banking -- Valuation -- Developing countries , Discounted cash flow , Capital assets pricing model , Capital -- Developing countries
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1200 , http://hdl.handle.net/10962/d1013057
- Description: Practitioners and academics in emerging markets are yet to agree on how best they can value companies in emerging markets. In contrast, academics and practitioners in developed markets seem to agree on mainstream valuation practices (Bruner, Eades, Harris and Haggins, 1998; Graham and Harvey, 2001). This study was therefore aimed at achieving such consensus with particular attention being paid to the emerging market banks. Emerging market banks are by no means small and are growing fast. Furthermore, these banks are currently involved in lots of cutting age economic activities such as mergers and acquisitions (M&A), joint ventures and strategic alliances which require sound valuation practices that are based on empirical evidence. The primary purpose of this research was to establish consensus of opinion among experts with regard to the valuation of banks in emerging markets. To achieve the purpose of this study the Delphi technique, which is a structured survey method that relies on a panel of experts to answer questionnaires in two or more Delphi rounds, was used to gather data and develop consensus among experts (Kalaian and Kasim, 2012). The main findings in this study pertain to aspects concerning the type of analysis considered by experts when analysing the performance of banks, how experts compare the discounted cash flow (DCF) approach to multiples valuation approach, the challenges encountered by experts when valuing banks in emerging markets, and how experts compute the cost of capital for banks in emerging markets. The main findings of this study can be summarised as follows: ∙ When analyzing the performance of banks, it is essential to conduct a bank-specific, industry and macroeconomic analysis; ∙ When estimating the future performance of banks, the time series analysis and an explicit forecast period of between 4-10 years may be used; ∙ When estimating the terminal value for banks in emerging markets, the perpetuity with growth is used; ∙ When computing the value for banks, the DCF valuation approach (equity DCF and DDM valuation models) are used as primary valuation methods and the relative valuation approach (P/E and P/BV ratio) are used as secondary valuation methods; ∙ The DCF valuation approach is considered as more accurate and popular when valuing banks in emerging markets; and ∙ When estimating the cost of equity, the capital asset pricing model (CAPM) is used.
- Full Text:
- Date Issued: 2014
Making sense of the lived and told experience of the 'ill' body : a phenomenological exploration into the storied and embodied nature of somatic or medically unexplained symtoms
- Authors: Haggard, Claire Louise
- Date: 2013-07-25
- Subjects: Psychological manifestations of general disease Somatization disorder Physician and patient -- Case studies
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3185 , http://hdl.handle.net/10962/d1008364
- Description: Despite a wealth of literature on the aetiology of somatic distress or somatization, somatic theory has failed to expand beyond a dualistic epistemology of causation. Within the primary health context where medically unexplained symptoms are characteristically articulated as literal, symbolic gestures of internal psychological processes, individuals' subjective accounts of somatic distress are reduced to objective phenomena and thus articulated on the grounds of absence. Within this context, the body as a lived, meaningful, perceiving subjectivity is silenced in favour of the corpse, thus rendering the somatizing individual's lived and subjective experience, expression and knowledge of somatic distress inaccessible. Instead, the somatizing individual is positioned within a domain of perturbed silence - a domain in which the professional's turning away or retreat from engaging somatization on the grounds of unique, subjective and corporeal experience, positions the patient/client as a passive, silent recipient whose somatic expressions as lived are overlooked. This study attempts to initiate a theoretical focus of departure from existing articulations of somatic distress through the development of a theoretical and epistemological framework that addresses some of the tensions inherent to contemporary somatic theory. In so doing, it employs embodiment philosophy and narrative methodology as a basis for a preliminary and critical investigation into a relatively neglected area of somatization research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Authors: Haggard, Claire Louise
- Date: 2013-07-25
- Subjects: Psychological manifestations of general disease Somatization disorder Physician and patient -- Case studies
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3185 , http://hdl.handle.net/10962/d1008364
- Description: Despite a wealth of literature on the aetiology of somatic distress or somatization, somatic theory has failed to expand beyond a dualistic epistemology of causation. Within the primary health context where medically unexplained symptoms are characteristically articulated as literal, symbolic gestures of internal psychological processes, individuals' subjective accounts of somatic distress are reduced to objective phenomena and thus articulated on the grounds of absence. Within this context, the body as a lived, meaningful, perceiving subjectivity is silenced in favour of the corpse, thus rendering the somatizing individual's lived and subjective experience, expression and knowledge of somatic distress inaccessible. Instead, the somatizing individual is positioned within a domain of perturbed silence - a domain in which the professional's turning away or retreat from engaging somatization on the grounds of unique, subjective and corporeal experience, positions the patient/client as a passive, silent recipient whose somatic expressions as lived are overlooked. This study attempts to initiate a theoretical focus of departure from existing articulations of somatic distress through the development of a theoretical and epistemological framework that addresses some of the tensions inherent to contemporary somatic theory. In so doing, it employs embodiment philosophy and narrative methodology as a basis for a preliminary and critical investigation into a relatively neglected area of somatization research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
Understandings of citizenship in policy and amongst matric learners in three KwaZulu Natal schools
- Authors: Van Lelyveld, Lara Diane
- Date: 2013
- Subjects: Citizenship -- Study and teaching -- Kwazulu-Natal (South Africa) Citizenship -- Social aspects -- Kwazulu-Natal (South Africa)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2847 , http://hdl.handle.net/10962/d1006116
- Description: This thesis explores the difference between the vision of citizenship within education policy and the actual experiences and understandings of citizenship by Matric learners. Citizenship as envisioned in policy is shown to differ significantly to citizenship as understood and experienced by the interview participants. The citizenship envisioned in policy presents the goal of an equal and united citizenry whereas interview participants described citizenship as unequal and hierarchical. In particular, the racial hierarchy enforced under Apartheid was found to dominate the learners’ experiences of citizenship. Despite progressive legislation, distribution of opportunities remains heavily weighted in favour of those in high-income environments. Education policies that determine the overall structure of the South African education system were selected for analysis. These are the Constitution, the South African Schools Act and the National Education Policy Act. These policies are analysed and a vision of South African citizenship is described as possessing the following characteristics. A common, equal citizenship in a united and transformed South Africa. A citizenship encouraging and mandating critical engagement, dialogue, openness and transparency. A citizenship founded on quality of life for all and developing the potential of each individual. A citizenship in which both state and citizen are responsible and accountable and operate within the rule of law. A citizenship underpinned by human dignity and freedom and security of the person. A citizenship in which there is respect for difference and self-determination and in which ‘unity in diversity’ plays a key role. Matric learners were drawn from three different schools in an area of Kwazulu-Natal. Each of these schools represents a ‘type’ of school in South Africa: a former Model C school, an independent school and a school based in a rural or township area. The interviews aimed not only to understand citizenship from the perspective of these learners, but also to understand how experiences of citizenship varied depending on race, gender and class.
- Full Text:
- Date Issued: 2013
- Authors: Van Lelyveld, Lara Diane
- Date: 2013
- Subjects: Citizenship -- Study and teaching -- Kwazulu-Natal (South Africa) Citizenship -- Social aspects -- Kwazulu-Natal (South Africa)
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2847 , http://hdl.handle.net/10962/d1006116
- Description: This thesis explores the difference between the vision of citizenship within education policy and the actual experiences and understandings of citizenship by Matric learners. Citizenship as envisioned in policy is shown to differ significantly to citizenship as understood and experienced by the interview participants. The citizenship envisioned in policy presents the goal of an equal and united citizenry whereas interview participants described citizenship as unequal and hierarchical. In particular, the racial hierarchy enforced under Apartheid was found to dominate the learners’ experiences of citizenship. Despite progressive legislation, distribution of opportunities remains heavily weighted in favour of those in high-income environments. Education policies that determine the overall structure of the South African education system were selected for analysis. These are the Constitution, the South African Schools Act and the National Education Policy Act. These policies are analysed and a vision of South African citizenship is described as possessing the following characteristics. A common, equal citizenship in a united and transformed South Africa. A citizenship encouraging and mandating critical engagement, dialogue, openness and transparency. A citizenship founded on quality of life for all and developing the potential of each individual. A citizenship in which both state and citizen are responsible and accountable and operate within the rule of law. A citizenship underpinned by human dignity and freedom and security of the person. A citizenship in which there is respect for difference and self-determination and in which ‘unity in diversity’ plays a key role. Matric learners were drawn from three different schools in an area of Kwazulu-Natal. Each of these schools represents a ‘type’ of school in South Africa: a former Model C school, an independent school and a school based in a rural or township area. The interviews aimed not only to understand citizenship from the perspective of these learners, but also to understand how experiences of citizenship varied depending on race, gender and class.
- Full Text:
- Date Issued: 2013
Fast track land reform programme and women in Goromonzi district, Zimbabwe
- Authors: Chakona, Loveness
- Date: 2012
- Subjects: Land reform -- Research -- Zimbabwe Land settlement -- Government policy -- Zimbabwe Land reform beneficiaries -- Zimbabwe Sex discrimination against women -- Zimbabwe Women's rights -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3317 , http://hdl.handle.net/10962/d1003105
- Description: From the year 2000, land became the key signifier for tackling the unfinished business of the decolonisation process in Zimbabwe, notably by rectifying the racially-based land injustices of the past through land redistribution. This took the form of the Fast Track Land Reform Programme (FTLRP). However, the racialised character and focus of the FTLRP tended to mask or at least downplay important gender dimensions to land in Zimbabwe. Colonial and post-colonial Zimbabwe (up to 2000) had instigated, propagated and reproduced land ownership, control and access along a distinctively patriarchal basis which left women either totally excluded or incorporated in an oppressive manner. This patriarchal structuring of the land question was rooted in institutions, practices and discourses. Although a burgeoning number of studies have been undertaken on the FTLRP, few have had a distinctively gender focus in seeking to identify, examine and assess the effect of the programme on patriarchal relations and the socio-economic livelihoods of rural women. This thesis makes a contribution to filling this lacuna by offering an empirically-rich study of land redistribution in one particular district in Zimbabwe, namely, Goromonzi District. This entails a focus on women on A1 resettlement farms in the district (and specifically women who came from nearby customary areas) and on women who continue to live in customary areas in the district. My thesis concludes that the FTLRP is seriously flawed in terms of addressing and tackling the patriarchal structures that underpin the Zimbabwean land question.
- Full Text:
- Date Issued: 2012
- Authors: Chakona, Loveness
- Date: 2012
- Subjects: Land reform -- Research -- Zimbabwe Land settlement -- Government policy -- Zimbabwe Land reform beneficiaries -- Zimbabwe Sex discrimination against women -- Zimbabwe Women's rights -- Zimbabwe
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3317 , http://hdl.handle.net/10962/d1003105
- Description: From the year 2000, land became the key signifier for tackling the unfinished business of the decolonisation process in Zimbabwe, notably by rectifying the racially-based land injustices of the past through land redistribution. This took the form of the Fast Track Land Reform Programme (FTLRP). However, the racialised character and focus of the FTLRP tended to mask or at least downplay important gender dimensions to land in Zimbabwe. Colonial and post-colonial Zimbabwe (up to 2000) had instigated, propagated and reproduced land ownership, control and access along a distinctively patriarchal basis which left women either totally excluded or incorporated in an oppressive manner. This patriarchal structuring of the land question was rooted in institutions, practices and discourses. Although a burgeoning number of studies have been undertaken on the FTLRP, few have had a distinctively gender focus in seeking to identify, examine and assess the effect of the programme on patriarchal relations and the socio-economic livelihoods of rural women. This thesis makes a contribution to filling this lacuna by offering an empirically-rich study of land redistribution in one particular district in Zimbabwe, namely, Goromonzi District. This entails a focus on women on A1 resettlement farms in the district (and specifically women who came from nearby customary areas) and on women who continue to live in customary areas in the district. My thesis concludes that the FTLRP is seriously flawed in terms of addressing and tackling the patriarchal structures that underpin the Zimbabwean land question.
- Full Text:
- Date Issued: 2012
The synthesis of fructooligosaccharides by the fructofuranosidase FopAp from Aspergillus niger
- Pindura, Mitchell Kingsley Chido
- Authors: Pindura, Mitchell Kingsley Chido
- Date: 2012
- Subjects: Aspergillus niger , Oligosaccharides
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4158 , http://hdl.handle.net/10962/d1018267
- Description: Fructooligosaccharides (FOS) are short-chain fructans with a terminal glucose moiety and are found naturally in many plant species. Besides their wide use as an alternative sweetener in food and beverage industry, FOS have shown great potential as neutraceuticals against diabetes, colon cancer and bowel disease. The uses of FOS are dependent on the degree of polymerisation that they exhibit. β-fructofuranosidase (FFase) and fructosyltransferase (FTase) enzymes are capable of synthesing FOS from carbohydrate raw materials such as chicory and sugar beet. The aim of this study was to investigate the synthesis of FOS of a pre-defined chain length, from sucrose, by the enzyme FopAp; a β-fructofuranosidase from Aspergillus niger. ATCC 20611. The crude enzyme FopAp was successfully purified, with a yield of 78.20 %, by ammonium sulphate precipitation and anion exchange chromatography. Two protein fractions, named FA and FB were shown to exhibit FFase activity. SDS PAGE analysis revealed two proteins with molecular weights of 112 kDa and 78 kDa, which were identified as a FFase and a hydrolase. Temperature and pH optima of 20 ºC and 9, respectively, were observed for the transfructosylation activity in the FFase. The purified FFase exhibited a half life of 1.5 hrs under optimal conditions. Substrate kinetic studies indicated a high hydrolytic activity at low sucrose concentrations, with Vmax and Km of 1.25 μmol/ml/min and 3.28 mM, respectively. Analysis by response surface methodology identified temperature and pH to be significant factors for the production of kestose and nystose, at a 95 % level of confidence. These findings were confirmed by neural networks constructed to identify optimal conditions of FOS synthesis.FOS synthesis was found to be optimal between pH 6 and pH 9 at 25 ºC. The factor of reaction time was found to be insignificant within the selected experimental constraints, for both FOS species. The findings of this investigation are very important as the foundations of a commercially viable synthetic process for the production of FOS.
- Full Text:
- Date Issued: 2012
- Authors: Pindura, Mitchell Kingsley Chido
- Date: 2012
- Subjects: Aspergillus niger , Oligosaccharides
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4158 , http://hdl.handle.net/10962/d1018267
- Description: Fructooligosaccharides (FOS) are short-chain fructans with a terminal glucose moiety and are found naturally in many plant species. Besides their wide use as an alternative sweetener in food and beverage industry, FOS have shown great potential as neutraceuticals against diabetes, colon cancer and bowel disease. The uses of FOS are dependent on the degree of polymerisation that they exhibit. β-fructofuranosidase (FFase) and fructosyltransferase (FTase) enzymes are capable of synthesing FOS from carbohydrate raw materials such as chicory and sugar beet. The aim of this study was to investigate the synthesis of FOS of a pre-defined chain length, from sucrose, by the enzyme FopAp; a β-fructofuranosidase from Aspergillus niger. ATCC 20611. The crude enzyme FopAp was successfully purified, with a yield of 78.20 %, by ammonium sulphate precipitation and anion exchange chromatography. Two protein fractions, named FA and FB were shown to exhibit FFase activity. SDS PAGE analysis revealed two proteins with molecular weights of 112 kDa and 78 kDa, which were identified as a FFase and a hydrolase. Temperature and pH optima of 20 ºC and 9, respectively, were observed for the transfructosylation activity in the FFase. The purified FFase exhibited a half life of 1.5 hrs under optimal conditions. Substrate kinetic studies indicated a high hydrolytic activity at low sucrose concentrations, with Vmax and Km of 1.25 μmol/ml/min and 3.28 mM, respectively. Analysis by response surface methodology identified temperature and pH to be significant factors for the production of kestose and nystose, at a 95 % level of confidence. These findings were confirmed by neural networks constructed to identify optimal conditions of FOS synthesis.FOS synthesis was found to be optimal between pH 6 and pH 9 at 25 ºC. The factor of reaction time was found to be insignificant within the selected experimental constraints, for both FOS species. The findings of this investigation are very important as the foundations of a commercially viable synthetic process for the production of FOS.
- Full Text:
- Date Issued: 2012