A Financial Sustainability Model for the South African Local Government
- Authors: Mhlanga, Shepherd
- Date: 2019
- Subjects: Local government -- South Africa -- Eastern Cape -- Finance Municipal finance -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , D.Admin
- Identifier: http://hdl.handle.net/10353/13715 , vital:39699
- Description: Local government financial sustainability leverages a local municipality’s capabilities to conceptualize and implement an array of its developmental programmes. This thesis evaluates the state of the initiatives for bolstering financial sustainability in the increasingly complex contemporary South African local government sphere. The motive of the study was to identify major paradoxes and a local government financial sustainability model that could be extracted and suggested for mitigating such constraints. Using a meta-synthesis as a principal technique in content analysis, findings revealed that major determinants of local government financial sustainability are often linked to the application of the four-step’s processes in strategic cyclical financial sustainability framework and three foundational constructs for financial sustainability management. The four-step’s processes in strategic cyclical financial sustainability framework were found to aid environmental analysis, identification of the sources of revenues and revenue generation, managing the utilization of the generated revenues and monitoring and evaluation. As it emerged from the findings, these positive effects of strategic cyclical financial sustainability framework are often illuminated by three foundational constructs for financial sustainability that leverage financial risk management, governance and leadership. However, in lieu of the application of relevant mitigating strategies, it also emerged from the analysis of the findings that initiatives that bolster financial sustainability may still be constrained by poor analysis and identification of the level of financial sustainability maturity. Other paradoxes were found to be linked to lack of suitable government financing models, poor strategic financial planning and budgeting as well as lack of effective models for managing equity. However, even in the midst of such paradoxes, findings still indicated that the concept of financial sustainability is a notion which is increasingly being emphasized by the South African local government sphere. To leverage municipal financial sustainability, most municipalities were found to use financial sustainability models and methods such as central financial grant system, SALGA’s model for financial sustainability, investment in revenue-generating activities and managing municipal operational efficiency as a driver of cost 4 | P a g e minimisation. However, despite such significant strides, findings still revealed that even with various socio-economic initiatives undertaken to leverage financial sustainability of the South African local government, the state of financial sustainability in the South African local government sphere seems to be at risk as viewed from such issues as compliance, systematic and strategic levels. As it emerged from the findings, this is attributable to the fact that most initiatives for improving financial sustainability in the South African local government are often still constrained by inadequate municipal capacity, limited income-generating activities, deficient local government procurement system and poor leadership and governance. Such findings seem consonant with theoretical findings that signified the major paradoxes of financial sustainability in the contemporary public sector organisations are often associated with poor analysis and identification of the level of financial sustainability maturity, lack of suitable government financing models, poor strategic financial planning and budgeting and lack of effective models for managing equity. Drawing from these findings, it is argued it is critical that the Department of Local Government adopts and applies the local government financial sustainability model akin to the conceptual model suggested in Figure 1. The application of such a model would require integration and use of the four main pillars (strategic financial planning, income diversification, sound financial administration and management, and own income generation) for local government financial sustainability, three foundational constructs (financial risk management, financial governance and financial ethical leadership) for local government financial sustainability, and three foundational nonfinancial constructs (political stability, fiscal and economic stability, forecasting and sensing to mitigate the devastating negative effects of natural calamities and disaster) for local government financial sustainability. It was further argued that all these must be accompanied by measurement of the overall maturity of the financial sustainability of the local municipality using four perspectives (liquidity, resilience, service and fiscal responsibility and public confidence) of local government financial sustainability in conjunction with the five spectrums (at risk, compliance-based, incremental, strategic and systematic) of local government financial sustainability.
- Full Text:
- Date Issued: 2019
- Authors: Mhlanga, Shepherd
- Date: 2019
- Subjects: Local government -- South Africa -- Eastern Cape -- Finance Municipal finance -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , D.Admin
- Identifier: http://hdl.handle.net/10353/13715 , vital:39699
- Description: Local government financial sustainability leverages a local municipality’s capabilities to conceptualize and implement an array of its developmental programmes. This thesis evaluates the state of the initiatives for bolstering financial sustainability in the increasingly complex contemporary South African local government sphere. The motive of the study was to identify major paradoxes and a local government financial sustainability model that could be extracted and suggested for mitigating such constraints. Using a meta-synthesis as a principal technique in content analysis, findings revealed that major determinants of local government financial sustainability are often linked to the application of the four-step’s processes in strategic cyclical financial sustainability framework and three foundational constructs for financial sustainability management. The four-step’s processes in strategic cyclical financial sustainability framework were found to aid environmental analysis, identification of the sources of revenues and revenue generation, managing the utilization of the generated revenues and monitoring and evaluation. As it emerged from the findings, these positive effects of strategic cyclical financial sustainability framework are often illuminated by three foundational constructs for financial sustainability that leverage financial risk management, governance and leadership. However, in lieu of the application of relevant mitigating strategies, it also emerged from the analysis of the findings that initiatives that bolster financial sustainability may still be constrained by poor analysis and identification of the level of financial sustainability maturity. Other paradoxes were found to be linked to lack of suitable government financing models, poor strategic financial planning and budgeting as well as lack of effective models for managing equity. However, even in the midst of such paradoxes, findings still indicated that the concept of financial sustainability is a notion which is increasingly being emphasized by the South African local government sphere. To leverage municipal financial sustainability, most municipalities were found to use financial sustainability models and methods such as central financial grant system, SALGA’s model for financial sustainability, investment in revenue-generating activities and managing municipal operational efficiency as a driver of cost 4 | P a g e minimisation. However, despite such significant strides, findings still revealed that even with various socio-economic initiatives undertaken to leverage financial sustainability of the South African local government, the state of financial sustainability in the South African local government sphere seems to be at risk as viewed from such issues as compliance, systematic and strategic levels. As it emerged from the findings, this is attributable to the fact that most initiatives for improving financial sustainability in the South African local government are often still constrained by inadequate municipal capacity, limited income-generating activities, deficient local government procurement system and poor leadership and governance. Such findings seem consonant with theoretical findings that signified the major paradoxes of financial sustainability in the contemporary public sector organisations are often associated with poor analysis and identification of the level of financial sustainability maturity, lack of suitable government financing models, poor strategic financial planning and budgeting and lack of effective models for managing equity. Drawing from these findings, it is argued it is critical that the Department of Local Government adopts and applies the local government financial sustainability model akin to the conceptual model suggested in Figure 1. The application of such a model would require integration and use of the four main pillars (strategic financial planning, income diversification, sound financial administration and management, and own income generation) for local government financial sustainability, three foundational constructs (financial risk management, financial governance and financial ethical leadership) for local government financial sustainability, and three foundational nonfinancial constructs (political stability, fiscal and economic stability, forecasting and sensing to mitigate the devastating negative effects of natural calamities and disaster) for local government financial sustainability. It was further argued that all these must be accompanied by measurement of the overall maturity of the financial sustainability of the local municipality using four perspectives (liquidity, resilience, service and fiscal responsibility and public confidence) of local government financial sustainability in conjunction with the five spectrums (at risk, compliance-based, incremental, strategic and systematic) of local government financial sustainability.
- Full Text:
- Date Issued: 2019
The implementation of National Health strategy (2009-2013) in Vungu District clinics, Midlands Province in Zimbabwe
- Authors: Mangwanya, M G
- Date: 2019
- Subjects: Medical care -- Zimbabwe Public health administration -- Zimbabwe National Health Strategy (Zimbabwe)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/18514 , vital:42579
- Description: The practice of strategy implementation is key to the public sector in Zimbabwe because it helps the government to be up to speed in providing services to the public. This research focused on the National Health Strategy 2009-2013 and its impact on health service delivery in Vungu Rural District Council Clinics. The research was based on qualitative desk study design which made use of existing data and semi structured interviews to understand the effect of the National Health Strategy on health service delivery in Vungu Rural Districts Council Clinics. From the literature reviewed and the data collected, it can be noted that lack of resources has had a huge effect on the execution of the strategy. The findings from the study show that the National Health Strategy was a good initiative. However, it lacked financial resources which posed challenges to the health workers in Vungu Rural District Council Clinics. The health workers were not very familiar with the National Health Strategy and this had a negative impact on its execution because they cannot execute a strategy that they are not familiar with. The study highlighted the importance of resources for the execution of the National Health Strategy. The study therefore sought to find ways the Zimbabwean Health System may formulate the health strategy with the limited resources in order to achieve desired goals. The Health Workers echoed the same sentiments that they needed resources for the implementation of the strategy. It is hoped that the findings would provide guidelines for the formulation and implementation of future health strategies. Recommendations given would ensure that there is utilisation of available resources, which would help in the execution of other health strategies to ensure efficient and effective health care service delivery. The recommendations are also intended to enhance the performance of health workers. Though the study was limited to Vungu Rural District Council Clinics the findings and recommendations would provide guidelines for other rural clinics as they use the National Health Strategy.
- Full Text:
- Date Issued: 2019
- Authors: Mangwanya, M G
- Date: 2019
- Subjects: Medical care -- Zimbabwe Public health administration -- Zimbabwe National Health Strategy (Zimbabwe)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/18514 , vital:42579
- Description: The practice of strategy implementation is key to the public sector in Zimbabwe because it helps the government to be up to speed in providing services to the public. This research focused on the National Health Strategy 2009-2013 and its impact on health service delivery in Vungu Rural District Council Clinics. The research was based on qualitative desk study design which made use of existing data and semi structured interviews to understand the effect of the National Health Strategy on health service delivery in Vungu Rural Districts Council Clinics. From the literature reviewed and the data collected, it can be noted that lack of resources has had a huge effect on the execution of the strategy. The findings from the study show that the National Health Strategy was a good initiative. However, it lacked financial resources which posed challenges to the health workers in Vungu Rural District Council Clinics. The health workers were not very familiar with the National Health Strategy and this had a negative impact on its execution because they cannot execute a strategy that they are not familiar with. The study highlighted the importance of resources for the execution of the National Health Strategy. The study therefore sought to find ways the Zimbabwean Health System may formulate the health strategy with the limited resources in order to achieve desired goals. The Health Workers echoed the same sentiments that they needed resources for the implementation of the strategy. It is hoped that the findings would provide guidelines for the formulation and implementation of future health strategies. Recommendations given would ensure that there is utilisation of available resources, which would help in the execution of other health strategies to ensure efficient and effective health care service delivery. The recommendations are also intended to enhance the performance of health workers. Though the study was limited to Vungu Rural District Council Clinics the findings and recommendations would provide guidelines for other rural clinics as they use the National Health Strategy.
- Full Text:
- Date Issued: 2019
Commerce powered by 'National culture'? : an assessment of "Wear Local" campaigns as tools for reinvigorating the textile and clothing industries in Ghana and South Africa
- Authors: Darku, Esther Naa Dodua
- Date: 2017
- Subjects: Textile industry -- Economic aspects -- Ghana Textile industry -- Economic aspects -- South Africa Sustainable development -- Ghana , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/2172 , vital:27619
- Description: This study examines the use of ‘cultural’ imagery and messaging as a tool to revitalise crucial national industries. Specifically, it examines the use of Wear Local campaigns in Ghana and South Africa as strategies to rejuvenate their textile industries and to make them viable in an increasingly competitive global market. Conceptualising Wear Local campaigns as possessing both cultural and economic imperatives, this study highlights how both factors contribute to making products of Buy Local campaigns marketable by showing their importance as both cultural and economic products. Using a descriptive-evaluative design, the study adopted a triangulated research approach comprising a survey, key informant interviews and document analysis. Survey questionnaires were administered to a total sample of 308 respondents in Ghana and South Africa. The qualitative phase of the study involved 10 key informant interviews (comprising textile labour unions, clothing designers, and government officials in both countries) and document/documentary research. The quantitative data were analysed using descriptive and inferential statistics, while the qualitative data were analysed using interpretive approaches, such as content analysis. The results indicate significant uses of national cultural elements in the campaign messaging in both Ghana and South Africa, as well as notable differences in the ways in which these campaigns resonated with consumers in the two countries. For instance, cultural differences accounted for high popularity of the campaign in Ghana and low popularity in South Africa. Following from these findings, the study concludes that the discourse on Buy Local and Wear Local, and the use of national culture in commerce, must go beyond the question of efficacy to examine the conditions under which these campaigns can become an effective economic/market tool. The study makes an important contribution to the existing knowledge on national culture, national economy and globalisation.
- Full Text:
- Date Issued: 2017
- Authors: Darku, Esther Naa Dodua
- Date: 2017
- Subjects: Textile industry -- Economic aspects -- Ghana Textile industry -- Economic aspects -- South Africa Sustainable development -- Ghana , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10353/2172 , vital:27619
- Description: This study examines the use of ‘cultural’ imagery and messaging as a tool to revitalise crucial national industries. Specifically, it examines the use of Wear Local campaigns in Ghana and South Africa as strategies to rejuvenate their textile industries and to make them viable in an increasingly competitive global market. Conceptualising Wear Local campaigns as possessing both cultural and economic imperatives, this study highlights how both factors contribute to making products of Buy Local campaigns marketable by showing their importance as both cultural and economic products. Using a descriptive-evaluative design, the study adopted a triangulated research approach comprising a survey, key informant interviews and document analysis. Survey questionnaires were administered to a total sample of 308 respondents in Ghana and South Africa. The qualitative phase of the study involved 10 key informant interviews (comprising textile labour unions, clothing designers, and government officials in both countries) and document/documentary research. The quantitative data were analysed using descriptive and inferential statistics, while the qualitative data were analysed using interpretive approaches, such as content analysis. The results indicate significant uses of national cultural elements in the campaign messaging in both Ghana and South Africa, as well as notable differences in the ways in which these campaigns resonated with consumers in the two countries. For instance, cultural differences accounted for high popularity of the campaign in Ghana and low popularity in South Africa. Following from these findings, the study concludes that the discourse on Buy Local and Wear Local, and the use of national culture in commerce, must go beyond the question of efficacy to examine the conditions under which these campaigns can become an effective economic/market tool. The study makes an important contribution to the existing knowledge on national culture, national economy and globalisation.
- Full Text:
- Date Issued: 2017
Land-use effects on mammal communities in the Fish-Kowie corridor, Eastern Cape, South Africa, with particular reference to carnivores
- Authors: Kok, Armand du Preez
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/561 , vital:19970
- Description: Human population growth is causing an increase in habitat transformation on a global scale, and this transformation is driven by changes in land-use practices. One consequence of habitat transformation is the negative effect it can have on mammal communities, especially carnivores. Carnivores are important components of ecosystems as they play an essential structuring role, but also often come into conflict with people. I studied the impact of land-use on mammalian diversity, the attitudes of landowners/managers towards carnivores, the distribution of carnivores, and the interactions among carnivore species in the Fish-Kowie corridor (FKC), an area of conservation concern, in the Eastern Cape, South Africa. Livestock and game farming are the two dominant land-use types in the FKC. Carnivore distribution data were collected between 2012 and 2014 using a robust camera trap survey that consisted of 432 camera stations (216 on livestock and 216 on game farms). In addition, the attitudes of 55 landowners/managers were assessed using semi- structured questionnaire interviews that were conducted in person. My results revealed that mammal diversity was similar on the two land-use types. However, individual species differed in their distribution on the two land-use types. In general, both livestock and game farmers had negative attitudes towards carnivores in the FKC, due to their depredation of valuable livestock and game species. Black-backed jackals (Canis mesomelas), caracals (Caracal caracal), leopards (Panthera pardus), and brown hyaenas (Parahyaena brunnea) were considered the most problematic carnivores, but sensitivity to land-use varied among these four species. Black- backed jackals had the highest occupancy rates of all four predators and were 3.8 times more likely to occupy sites on game farms compared to livestock farms. By contrast, leopards and brown hyaenas were only detected on game farms, and caracals did not appear to be sensitive to the effects of land-use. In general, the interactions among carnivores were weak and were likely driven by carnivore diversity, resource partitioning, and anthropogenic pressures. While there were many subtle differences in the distribution of mammal species and human attitudes towards wildlife on livestock and game farms in the FKC, there were also many similarities. My study has produced results that can be used by the FKC community to better understand how mammals and humans interact across the landscape, information that will ultimately contribute to future conservation planning in the area.
- Full Text:
- Date Issued: 2016
- Authors: Kok, Armand du Preez
- Date: 2016
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/561 , vital:19970
- Description: Human population growth is causing an increase in habitat transformation on a global scale, and this transformation is driven by changes in land-use practices. One consequence of habitat transformation is the negative effect it can have on mammal communities, especially carnivores. Carnivores are important components of ecosystems as they play an essential structuring role, but also often come into conflict with people. I studied the impact of land-use on mammalian diversity, the attitudes of landowners/managers towards carnivores, the distribution of carnivores, and the interactions among carnivore species in the Fish-Kowie corridor (FKC), an area of conservation concern, in the Eastern Cape, South Africa. Livestock and game farming are the two dominant land-use types in the FKC. Carnivore distribution data were collected between 2012 and 2014 using a robust camera trap survey that consisted of 432 camera stations (216 on livestock and 216 on game farms). In addition, the attitudes of 55 landowners/managers were assessed using semi- structured questionnaire interviews that were conducted in person. My results revealed that mammal diversity was similar on the two land-use types. However, individual species differed in their distribution on the two land-use types. In general, both livestock and game farmers had negative attitudes towards carnivores in the FKC, due to their depredation of valuable livestock and game species. Black-backed jackals (Canis mesomelas), caracals (Caracal caracal), leopards (Panthera pardus), and brown hyaenas (Parahyaena brunnea) were considered the most problematic carnivores, but sensitivity to land-use varied among these four species. Black- backed jackals had the highest occupancy rates of all four predators and were 3.8 times more likely to occupy sites on game farms compared to livestock farms. By contrast, leopards and brown hyaenas were only detected on game farms, and caracals did not appear to be sensitive to the effects of land-use. In general, the interactions among carnivores were weak and were likely driven by carnivore diversity, resource partitioning, and anthropogenic pressures. While there were many subtle differences in the distribution of mammal species and human attitudes towards wildlife on livestock and game farms in the FKC, there were also many similarities. My study has produced results that can be used by the FKC community to better understand how mammals and humans interact across the landscape, information that will ultimately contribute to future conservation planning in the area.
- Full Text:
- Date Issued: 2016
The influence of indigenous languages on Ugandan English as used in the media
- Authors: Tukwasibwe, Constance
- Date: 2014
- Subjects: Mass media and language -- Uganda , Languages in contact -- Uganda , English language -- Uganda , Language transfer (Language learning) -- Uganda , Communication and culture -- Uganda , Bilingualism -- Uganda , Linguistic demography -- Uganda , Uganda -- Languages
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3646 , http://hdl.handle.net/10962/d1015637
- Description: When two or more languages come in contact, they influence each other in various ways, for example through word borrowing, transfer of sounds, morphology and syntax taken from one language system and imported to another. In this study, the primary concern is on the indigenous communities of Uganda learning the English language, plus the influence that this interaction brings into the linguistic space. Bringing the Ugandan multilingual situation into perspective, the study looks at how the English language has interacted with the local languages and the local speech habits, customs and traditions of the indigenous people, to the extent that it has been indigenized. Some word usage results in miscommunication due to the socio-cultural uniqueness of Ugandan cultural expressions. As an example, because of the practice of polygamy in most Ugandan cultures, words like co-wife are coined to mean 'a woman who shares a husband, or a husband's other wife', a word that is absent in both the language and culture of native English speakers. Furthermore some words are formed by calquing some indigenous language expressions, e.g. 'to eat money' or 'to eat cash', an expression that is calqued from the Luganda phrase, kulya sente. Such word coinages are meant to fill the 'shortfall' where the English language fails to provide adequate equivalents. Understanding the context of this kind of English usage and the influence from the indigenous languages is helpful in handling inter-cultural discourses, as the same expression may convey different senses to different people in different contexts. So then, this study deals with some peculiarities of Ugandan English, namely; the features of Ugandan English grammar which are influenced by the indigenous languages. Evidence from the Corpus of Ugandan English is explored to establish that indigenous languages in Uganda have a significant influence on the English language variety spoken in the country, and that a large part of English bilingual speakers cannot speak English without transferring the features from their mother tongue or indeed, switching and mixing codes. A British corpus was used for the purposes of comparison with Ugandan English. The research was conducted in Uganda, drawing data from English newspapers, radio and television talk -shows that were recorded to provide a structural analysis of the contact situations. The result of the study points to the fact that, indeed, the phonological, morpho-syntactic and semantic characteristics of Ugandan English have a considerable amount of influence from indigenous local languages. This study is hinged on the assumption that when indigenous languages and the target language come together in a linguistic contact situation, the resulting variety would exhibit distinct phonological, lexical, grammatical and semantic/pragmatic features ( cf. Sankoff, 2001; Thomason, 1995; Thomason & Kaufman, 1988; Winford, 2005). However, some of these innovations have attracted criticism from 'prescriptivists' such as Quirk (1985, 1988, 1990); Gaudio (2011); and Abbot (1991) who perceive them as 'nonstandard', 'incorrect English language usage' and a 'direct translation from the language user's mother tongue into English'. Yet, indigenous languages continue to play important roles in shaping the kind of English language usage in Uganda.
- Full Text:
- Date Issued: 2014
- Authors: Tukwasibwe, Constance
- Date: 2014
- Subjects: Mass media and language -- Uganda , Languages in contact -- Uganda , English language -- Uganda , Language transfer (Language learning) -- Uganda , Communication and culture -- Uganda , Bilingualism -- Uganda , Linguistic demography -- Uganda , Uganda -- Languages
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3646 , http://hdl.handle.net/10962/d1015637
- Description: When two or more languages come in contact, they influence each other in various ways, for example through word borrowing, transfer of sounds, morphology and syntax taken from one language system and imported to another. In this study, the primary concern is on the indigenous communities of Uganda learning the English language, plus the influence that this interaction brings into the linguistic space. Bringing the Ugandan multilingual situation into perspective, the study looks at how the English language has interacted with the local languages and the local speech habits, customs and traditions of the indigenous people, to the extent that it has been indigenized. Some word usage results in miscommunication due to the socio-cultural uniqueness of Ugandan cultural expressions. As an example, because of the practice of polygamy in most Ugandan cultures, words like co-wife are coined to mean 'a woman who shares a husband, or a husband's other wife', a word that is absent in both the language and culture of native English speakers. Furthermore some words are formed by calquing some indigenous language expressions, e.g. 'to eat money' or 'to eat cash', an expression that is calqued from the Luganda phrase, kulya sente. Such word coinages are meant to fill the 'shortfall' where the English language fails to provide adequate equivalents. Understanding the context of this kind of English usage and the influence from the indigenous languages is helpful in handling inter-cultural discourses, as the same expression may convey different senses to different people in different contexts. So then, this study deals with some peculiarities of Ugandan English, namely; the features of Ugandan English grammar which are influenced by the indigenous languages. Evidence from the Corpus of Ugandan English is explored to establish that indigenous languages in Uganda have a significant influence on the English language variety spoken in the country, and that a large part of English bilingual speakers cannot speak English without transferring the features from their mother tongue or indeed, switching and mixing codes. A British corpus was used for the purposes of comparison with Ugandan English. The research was conducted in Uganda, drawing data from English newspapers, radio and television talk -shows that were recorded to provide a structural analysis of the contact situations. The result of the study points to the fact that, indeed, the phonological, morpho-syntactic and semantic characteristics of Ugandan English have a considerable amount of influence from indigenous local languages. This study is hinged on the assumption that when indigenous languages and the target language come together in a linguistic contact situation, the resulting variety would exhibit distinct phonological, lexical, grammatical and semantic/pragmatic features ( cf. Sankoff, 2001; Thomason, 1995; Thomason & Kaufman, 1988; Winford, 2005). However, some of these innovations have attracted criticism from 'prescriptivists' such as Quirk (1985, 1988, 1990); Gaudio (2011); and Abbot (1991) who perceive them as 'nonstandard', 'incorrect English language usage' and a 'direct translation from the language user's mother tongue into English'. Yet, indigenous languages continue to play important roles in shaping the kind of English language usage in Uganda.
- Full Text:
- Date Issued: 2014
Synthetic, spectrometric and computer modelling studies of novel ATP analogues
- Gxoyiya, Babalwa Siliziwe Blossom
- Authors: Gxoyiya, Babalwa Siliziwe Blossom
- Date: 2008
- Subjects: Spectrum analysis Tuberculosis -- Treatment Chemotherapy Adenosine triphosphate Adenosine triphosphate -- Synthesis Adenosine triphosphate -- Computer simulation Adenosine triphosphate -- Spectrometric imaging Glutamine synthetase Tuberculosis -- Chemotherapy
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4386 , http://hdl.handle.net/10962/d1005051
- Description: This study has been concerned with the design and synthesis of A TP analogues with the potential to act as inhibitors of glutamine synthetase - a novel target for therapeutic intervention in the treatment of tuberculosis. Using a structural -analogy approach, various 3-indolylalkanoic acid, benzimidazole and pyrazolo[3,4-dJpyrimidine derivatives have been prepared and characterized. Alkylation of the heterocyclic bases using 4-(bromomethyl)-2,2-dimethyl-1 ,3-d ioxolane, 2-(bromomethoxy)ethyl acetate and 2-(chloroethoxy)ethanol in the presence of either NaH or BulOK afforded the corresponding N-alkylated derivatives of benzimidazole and 4-aminopyrazolo[3,4-dJpyrimidine (4-APP). Similar reactions with 3-indo lylalkanoic esters resulted in O-alkyl cleavage with the formation of new esters. Alkylation of benzimidazole with allyl bromide, 4-bromobutene and 2-methylbut-2-ene has also been shown to afford the corresponding l-alkenylbenzimidazoles in moderate to excellent yield (43-96%). Subsequent oxidation of these products using CTAP, gave the dihydroxy derivatives in poor to good yields (26-77%). Phosphorylation of various hydroxy derivatives of benzimidazole and 4-APP has been achieved using diethyl chlorophosphate to afford the corresponding monophosphate and 1,2-diphosphate esters. Glycosylation of each of the heterocyclic bases has been successfully achieved using 1,2,3,4,6-penta-O-acetyl-D-glucopyranose and SnCl4 in acetonitri le, while methanolysis of the resulting tetraacetates, using methanolic NaOMe, afforded the hydroxy derivatives in good yield (50-70%). Various 1- and 2-dimensional NMR spectroscopic methods (e.g., IH, 13C, lip, COSY, HSQC and HMBC) have been used to confirm the structures of the synthesized A IP analogues. The application of NMR prediction programmes has been explored, permitting assessment of their agreement with the experimental data and confirmation of assigned structures. High-resolution electron impact (EI) mass spectrometric data have been used to explore the mass fragmentation pathways exhibited by selected derivatives, and certain common fragmentations have been identified. Molecular modelling of selected products as potential glutamine synthetase ligands has been performed on the Accelrys Cerius2 platform, and interactive receptor-ligand docking studies have been conducted using the Ligand-Fit module. These studies have revealed possible hydrogen-boding interactions between the selected analogues and various amino acid residues in the glutamine synthetase active site.
- Full Text:
- Date Issued: 2008
- Authors: Gxoyiya, Babalwa Siliziwe Blossom
- Date: 2008
- Subjects: Spectrum analysis Tuberculosis -- Treatment Chemotherapy Adenosine triphosphate Adenosine triphosphate -- Synthesis Adenosine triphosphate -- Computer simulation Adenosine triphosphate -- Spectrometric imaging Glutamine synthetase Tuberculosis -- Chemotherapy
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4386 , http://hdl.handle.net/10962/d1005051
- Description: This study has been concerned with the design and synthesis of A TP analogues with the potential to act as inhibitors of glutamine synthetase - a novel target for therapeutic intervention in the treatment of tuberculosis. Using a structural -analogy approach, various 3-indolylalkanoic acid, benzimidazole and pyrazolo[3,4-dJpyrimidine derivatives have been prepared and characterized. Alkylation of the heterocyclic bases using 4-(bromomethyl)-2,2-dimethyl-1 ,3-d ioxolane, 2-(bromomethoxy)ethyl acetate and 2-(chloroethoxy)ethanol in the presence of either NaH or BulOK afforded the corresponding N-alkylated derivatives of benzimidazole and 4-aminopyrazolo[3,4-dJpyrimidine (4-APP). Similar reactions with 3-indo lylalkanoic esters resulted in O-alkyl cleavage with the formation of new esters. Alkylation of benzimidazole with allyl bromide, 4-bromobutene and 2-methylbut-2-ene has also been shown to afford the corresponding l-alkenylbenzimidazoles in moderate to excellent yield (43-96%). Subsequent oxidation of these products using CTAP, gave the dihydroxy derivatives in poor to good yields (26-77%). Phosphorylation of various hydroxy derivatives of benzimidazole and 4-APP has been achieved using diethyl chlorophosphate to afford the corresponding monophosphate and 1,2-diphosphate esters. Glycosylation of each of the heterocyclic bases has been successfully achieved using 1,2,3,4,6-penta-O-acetyl-D-glucopyranose and SnCl4 in acetonitri le, while methanolysis of the resulting tetraacetates, using methanolic NaOMe, afforded the hydroxy derivatives in good yield (50-70%). Various 1- and 2-dimensional NMR spectroscopic methods (e.g., IH, 13C, lip, COSY, HSQC and HMBC) have been used to confirm the structures of the synthesized A IP analogues. The application of NMR prediction programmes has been explored, permitting assessment of their agreement with the experimental data and confirmation of assigned structures. High-resolution electron impact (EI) mass spectrometric data have been used to explore the mass fragmentation pathways exhibited by selected derivatives, and certain common fragmentations have been identified. Molecular modelling of selected products as potential glutamine synthetase ligands has been performed on the Accelrys Cerius2 platform, and interactive receptor-ligand docking studies have been conducted using the Ligand-Fit module. These studies have revealed possible hydrogen-boding interactions between the selected analogues and various amino acid residues in the glutamine synthetase active site.
- Full Text:
- Date Issued: 2008
Rights to reality - the right to social security, with particular emphasis on the legal resources centre's welfare project in the Eastern Cape
- Authors: Delany, Mairéad Christine
- Date: 2003
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:21027 , http://hdl.handle.net/10962/6052
- Description: This research addresses the question of whether the courts have been used effectively to enforce the right to social security in the Eastern Cape. The nature of the right to social security is discussed and placed in the context of constitutional developments in South Africa and South Africa's obligations in terms of international law. The enforcement of socio-economic rights and legislation regarding social assistance is also discussed in detail, along with the problems associated with the social security system such as the gaps in the system, the impact of HIV / AIDS and the problems created by the amalgamation of various administrations. The history of the Legal Resources Centre, a non-governmental organisation which has been involved in public interest law for twenty four years, is detailed. The Grahamstown office's litigation campaign against the Eastern Cape Department of Welfare is then discussed and six landmark cases are analysed in detail. A discussion of the jurisprudential significance and impact of each case on the development of South African administrative and constitutional law follows. A series of stories reported in the press illustrate the human aspect of the campaign and balance the legal argument. These stories may suggest that the Constitution's commitment to social justice and the government's commitment to the principles of Batho Pete are merely noble ideals for many people in the province, but it is argued that the LRC's campaign has made a vast contribution towards making these ideals a reality on the ground. The expert opinions of various groups interviewed during the course of this research regarding the impact of the LRC's litigation campaign are discussed, and the conclusion is drawn that it has indeed had a positive effect. They include paralegals at Advice Offices around the province, legal practitioners from the LRC, a private legal practitioner, several representatives of the Black Sash, a former MEC for Health and Welfare in the Eastern Cape Provincial Government, an official from the Department, and a leader of the Anglican Church in the province. In conclusion it is submitted that, but for the LRC's litigation campaign, the situation in the Eastern Cape would not have improved to the extent it has and may even have deteriorated further. Furthermore, it is submitted that as a result of the litigation campaign, the right to social security, and particularly the right to social assistance, is more accessible and more of a reality on the ground.
- Full Text:
- Date Issued: 2003
- Authors: Delany, Mairéad Christine
- Date: 2003
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:21027 , http://hdl.handle.net/10962/6052
- Description: This research addresses the question of whether the courts have been used effectively to enforce the right to social security in the Eastern Cape. The nature of the right to social security is discussed and placed in the context of constitutional developments in South Africa and South Africa's obligations in terms of international law. The enforcement of socio-economic rights and legislation regarding social assistance is also discussed in detail, along with the problems associated with the social security system such as the gaps in the system, the impact of HIV / AIDS and the problems created by the amalgamation of various administrations. The history of the Legal Resources Centre, a non-governmental organisation which has been involved in public interest law for twenty four years, is detailed. The Grahamstown office's litigation campaign against the Eastern Cape Department of Welfare is then discussed and six landmark cases are analysed in detail. A discussion of the jurisprudential significance and impact of each case on the development of South African administrative and constitutional law follows. A series of stories reported in the press illustrate the human aspect of the campaign and balance the legal argument. These stories may suggest that the Constitution's commitment to social justice and the government's commitment to the principles of Batho Pete are merely noble ideals for many people in the province, but it is argued that the LRC's campaign has made a vast contribution towards making these ideals a reality on the ground. The expert opinions of various groups interviewed during the course of this research regarding the impact of the LRC's litigation campaign are discussed, and the conclusion is drawn that it has indeed had a positive effect. They include paralegals at Advice Offices around the province, legal practitioners from the LRC, a private legal practitioner, several representatives of the Black Sash, a former MEC for Health and Welfare in the Eastern Cape Provincial Government, an official from the Department, and a leader of the Anglican Church in the province. In conclusion it is submitted that, but for the LRC's litigation campaign, the situation in the Eastern Cape would not have improved to the extent it has and may even have deteriorated further. Furthermore, it is submitted that as a result of the litigation campaign, the right to social security, and particularly the right to social assistance, is more accessible and more of a reality on the ground.
- Full Text:
- Date Issued: 2003
The integrative nature of the synoptic weather map in relation to adolescent cognitive structures and the teaching of senior secondary meteorology-climatology
- Authors: Van Jaarsveld, Pieter Paul
- Date: 1988
- Subjects: Meteorology -- Study and teaching (Secondary) Climatology -- Study and teaching (Secondary) Cognition in children
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1843 , http://hdl.handle.net/10962/d1004377
- Description: A poorly consolidated concept base creates considerable difficulty amongst adolescents when it comes to the higher order task of analyzing complex, abstract and scientific weather phenomena as they appear on synoptic charts. The nature of the difficulties which they experience tends to encourage them to resort to the rote memorisation of concepts rather than understanding them. Kuhn (1962) avers that concepts, not enquiry methods, are at the core of rational thought. A well taught concept becomes a well developed mental construct which encourages understanding. It is the author's firm belief that in order for pupils to come to a thorough understanding of senior secondary meteorology - climatology and the synoptic chart, teaching of basic concepts should be graded and sequential. This thesis attempts to show the difficulties inherent in synoptic climatology. It relates these difficulties to adolescent cognitive development. Within this framework, the syllabus and past examinations of the Cape Education Department, and textbooks are examined. Teachers' views and pupils' understanding are gauged through the analyses of questionnaires and worksheets respectively. Conclusions are drawn and the problems which teachers and pupils encounter are addressed.
- Full Text:
- Date Issued: 1988
- Authors: Van Jaarsveld, Pieter Paul
- Date: 1988
- Subjects: Meteorology -- Study and teaching (Secondary) Climatology -- Study and teaching (Secondary) Cognition in children
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1843 , http://hdl.handle.net/10962/d1004377
- Description: A poorly consolidated concept base creates considerable difficulty amongst adolescents when it comes to the higher order task of analyzing complex, abstract and scientific weather phenomena as they appear on synoptic charts. The nature of the difficulties which they experience tends to encourage them to resort to the rote memorisation of concepts rather than understanding them. Kuhn (1962) avers that concepts, not enquiry methods, are at the core of rational thought. A well taught concept becomes a well developed mental construct which encourages understanding. It is the author's firm belief that in order for pupils to come to a thorough understanding of senior secondary meteorology - climatology and the synoptic chart, teaching of basic concepts should be graded and sequential. This thesis attempts to show the difficulties inherent in synoptic climatology. It relates these difficulties to adolescent cognitive development. Within this framework, the syllabus and past examinations of the Cape Education Department, and textbooks are examined. Teachers' views and pupils' understanding are gauged through the analyses of questionnaires and worksheets respectively. Conclusions are drawn and the problems which teachers and pupils encounter are addressed.
- Full Text:
- Date Issued: 1988
Community leadership in Grahamstown
- Authors: Van der Merwe, Hendrik W
- Date: 1967
- Subjects: Sociology, Urban -- South Africa -- Grahamstown , Community leadership -- South Africa -- Grahamstown , Community development, Urban -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3390 , http://hdl.handle.net/10962/d1014564
- Description: In this study an analysis was made of the leadership structure of the community of Grahamstown. It was hypothesized that the leadership structure is pluralistic i.e. that leaders are divided along themselves on different issues. An historical and documentary analysis of various aspects of community life revealed that leaders were not united on almost all issues. An analysis of the voluntary associations in which the top leaders took an active part revealed great discrepancy in terms of orientation toward the community, society, and social exclusiveness. A schedule was administered to 90 leaders who were identified by the Cooperating- Informant Technique. Data. were collected about their background characteristics, attitudes toward certain local issues and their general ideological orientations. It was found that stands taken on local issues can best be interpreted in terms of ideological orientation. We conclude that local community leadership is pluralistic. In view of the relationship between local issues and the larger society, several selected problems merit further investigation.
- Full Text:
- Date Issued: 1967
- Authors: Van der Merwe, Hendrik W
- Date: 1967
- Subjects: Sociology, Urban -- South Africa -- Grahamstown , Community leadership -- South Africa -- Grahamstown , Community development, Urban -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3390 , http://hdl.handle.net/10962/d1014564
- Description: In this study an analysis was made of the leadership structure of the community of Grahamstown. It was hypothesized that the leadership structure is pluralistic i.e. that leaders are divided along themselves on different issues. An historical and documentary analysis of various aspects of community life revealed that leaders were not united on almost all issues. An analysis of the voluntary associations in which the top leaders took an active part revealed great discrepancy in terms of orientation toward the community, society, and social exclusiveness. A schedule was administered to 90 leaders who were identified by the Cooperating- Informant Technique. Data. were collected about their background characteristics, attitudes toward certain local issues and their general ideological orientations. It was found that stands taken on local issues can best be interpreted in terms of ideological orientation. We conclude that local community leadership is pluralistic. In view of the relationship between local issues and the larger society, several selected problems merit further investigation.
- Full Text:
- Date Issued: 1967
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