A proposed baseline South African antimicrobial stewardship curriculum for the Bachelor of Pharmacy programme
- Authors: Khan, Yasmine
- Date: 2019
- Subjects: Pharmacy -- Study and teaching -- South Africa , Pharmacy -- Practice -- South Africa Drug utilization -- Dissertations Drug utilization -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/35752 , vital:33805
- Description: Antimicrobial stewardship refers to the healthcare practice which ensures the judicious and appropriate prescribing of antimicrobial agents. The primary purpose of antimicrobial stewardship entails minimising the progression of antimicrobial resistance; the rise of which is recognised as a threat to global health and safety. The pharmacist is recognised nationally and internationally as a key role player in the implementation of antimicrobial stewardship. Education of healthcare practitioners in antimicrobial stewardship is a recognised strategic enabler for the containment of antimicrobial resistance in South Africa. The primary aim of the study was to develop a proposed baseline antimicrobial stewardship curriculum which is suitable for implementation into the Bachelor of Pharmacy programmes offered by South African schools of pharmacy. The aims and objectives of the study were achieved through the conduction of four study phases: the content analysis, academic review, expert consultation and curriculum development. The content analysis investigated the structure and content of international antimicrobial stewardship curricula, and the national policy governing antimicrobial stewardship implementation in South Africa. Frequency distributions of trends from the reviewed literature informed the development of the initial draft antimicrobial stewardship curriculum for pharmacy students. In terms of content, the principles which emerges with high frequency, which were thus emphasised in the initial draft curriculum, included: the strategic objectives (governance, surveillance, antimicrobial stewardship and infection prevention); strategic enablers (education, communication, legislation and research); dose optimisation; audit and feedback; formulary restriction; collaboration; pre-authorisation; and de-escalation. Available literature did not provide extensive detail regarding the curriculum structure utilised internationally, particularly with regards to the number of contact hours dedicated to the curriculum content and the year level at which antimicrobial stewardship was incorporated in the degree programme (variable between studies). From the content analysis it was evident that a mixed methods pedagogy and use of multiple assessment techniques were recommended. The academic review phase allowed for further insight to be obtained into the content and structure of antimicrobial stewardship curriculum content which was presented in the pre-existing Bachelor of Pharmacy degree programmes. Furthermore, the academic review required that nominated participants from each school of pharmacy indicate which antimicrobial prescribing principles should be incorporated in the proposed baseline antimicrobial stewardship curriculum. The results of the academic review phase were collated with the content analysis in order to develop the updated draft antimicrobial stewardship curriculum. It was interesting to note that large variation in content and structure related to antimicrobial stewardship which was presented by the various schools of pharmacy in South Africa. In terms of curriculum content, recommendations made by academic professionals informed the development of relative importance groupings, which allowed for the various antimicrobial stewardship principles to be tiered according to importance for inclusion in the proposed baseline antimicrobial stewardship curriculum. The large variation in antimicrobial stewardship curriculum structure posed as a challenge for the development of the proposed baseline curriculum, requiring that the structure remain flexible in order for feasible incorporation into the pre-existing Bachelor of Pharmacy degree programmes offered by the various schools of pharmacy in South Africa. The expert consultation phase explored the perceptions of multiple key health disciplines who serve as part of antimicrobial stewardship teams in South Africa with regards to the role of the pharmacist in antimicrobial stewardship; and the minimum level of antimicrobial stewardship knowledge and skills which pharmacy students should possess prior to entry into practice. The results of the expert consultation phase were collated with the results of the content analysis and academic review phase in order to develop the final proposed baseline antimicrobial stewardship curriculum. The findings of the expert consultation phase indicated great variability regarding the perceived role of the pharmacist in antimicrobial stewardship within and between health disciplines. Furthermore, the relative perceived importance of various antimicrobial stewardship strategies and antimicrobial prescribing principles were explored, which informed the tiering of content in the final proposed antimicrobial stewardship curriculum.
- Full Text:
- Date Issued: 2019
- Authors: Khan, Yasmine
- Date: 2019
- Subjects: Pharmacy -- Study and teaching -- South Africa , Pharmacy -- Practice -- South Africa Drug utilization -- Dissertations Drug utilization -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/35752 , vital:33805
- Description: Antimicrobial stewardship refers to the healthcare practice which ensures the judicious and appropriate prescribing of antimicrobial agents. The primary purpose of antimicrobial stewardship entails minimising the progression of antimicrobial resistance; the rise of which is recognised as a threat to global health and safety. The pharmacist is recognised nationally and internationally as a key role player in the implementation of antimicrobial stewardship. Education of healthcare practitioners in antimicrobial stewardship is a recognised strategic enabler for the containment of antimicrobial resistance in South Africa. The primary aim of the study was to develop a proposed baseline antimicrobial stewardship curriculum which is suitable for implementation into the Bachelor of Pharmacy programmes offered by South African schools of pharmacy. The aims and objectives of the study were achieved through the conduction of four study phases: the content analysis, academic review, expert consultation and curriculum development. The content analysis investigated the structure and content of international antimicrobial stewardship curricula, and the national policy governing antimicrobial stewardship implementation in South Africa. Frequency distributions of trends from the reviewed literature informed the development of the initial draft antimicrobial stewardship curriculum for pharmacy students. In terms of content, the principles which emerges with high frequency, which were thus emphasised in the initial draft curriculum, included: the strategic objectives (governance, surveillance, antimicrobial stewardship and infection prevention); strategic enablers (education, communication, legislation and research); dose optimisation; audit and feedback; formulary restriction; collaboration; pre-authorisation; and de-escalation. Available literature did not provide extensive detail regarding the curriculum structure utilised internationally, particularly with regards to the number of contact hours dedicated to the curriculum content and the year level at which antimicrobial stewardship was incorporated in the degree programme (variable between studies). From the content analysis it was evident that a mixed methods pedagogy and use of multiple assessment techniques were recommended. The academic review phase allowed for further insight to be obtained into the content and structure of antimicrobial stewardship curriculum content which was presented in the pre-existing Bachelor of Pharmacy degree programmes. Furthermore, the academic review required that nominated participants from each school of pharmacy indicate which antimicrobial prescribing principles should be incorporated in the proposed baseline antimicrobial stewardship curriculum. The results of the academic review phase were collated with the content analysis in order to develop the updated draft antimicrobial stewardship curriculum. It was interesting to note that large variation in content and structure related to antimicrobial stewardship which was presented by the various schools of pharmacy in South Africa. In terms of curriculum content, recommendations made by academic professionals informed the development of relative importance groupings, which allowed for the various antimicrobial stewardship principles to be tiered according to importance for inclusion in the proposed baseline antimicrobial stewardship curriculum. The large variation in antimicrobial stewardship curriculum structure posed as a challenge for the development of the proposed baseline curriculum, requiring that the structure remain flexible in order for feasible incorporation into the pre-existing Bachelor of Pharmacy degree programmes offered by the various schools of pharmacy in South Africa. The expert consultation phase explored the perceptions of multiple key health disciplines who serve as part of antimicrobial stewardship teams in South Africa with regards to the role of the pharmacist in antimicrobial stewardship; and the minimum level of antimicrobial stewardship knowledge and skills which pharmacy students should possess prior to entry into practice. The results of the expert consultation phase were collated with the results of the content analysis and academic review phase in order to develop the final proposed baseline antimicrobial stewardship curriculum. The findings of the expert consultation phase indicated great variability regarding the perceived role of the pharmacist in antimicrobial stewardship within and between health disciplines. Furthermore, the relative perceived importance of various antimicrobial stewardship strategies and antimicrobial prescribing principles were explored, which informed the tiering of content in the final proposed antimicrobial stewardship curriculum.
- Full Text:
- Date Issued: 2019
Indigenous cereal crops and food security issues in Zimbabwe: the case of Matabeleland Provinces
- Authors: Nyathi, Vuyiswa Sandra
- Date: 2019
- Subjects: Food security Farms, Small
- Language: English
- Type: Thesis , Doctoral , PhD (Developmental Studies)
- Identifier: http://hdl.handle.net/10353/17070 , vital:40845
- Description: The study endeavoured to find out how indigenous cereal crops in the form of sorghum, pearl millet and finger millet, popularly known as small grain, would help in increasing cereal production in the dry regions of Zimbabwe so as to alleviate food insecurity. For the past decade the nation’s cereal production has been on the decline with the country having to rely on grain imports from neighbouring countries to prevent hunger. Studies that have been carried out have indicated that these indigenous cereal crops are better suited for semi-arid regions like Matabeleland, used as a case study, where maize has almost always been a failing crop. The study examined representations of smallholder farmers through interviews held with agricultural personnel in Matabeleland North and Matabeleland South Provinces. The study argues that instead of relying on maize only as a staple crop, in the semiarid regions of the country, indigenous cereal crops are suitable alternative staple crops in Zimbabwe. Indications from the findings of the study are that diversification of staple crop production should stress the importance of state mediation, distribution and promotion of indigenous cereal crops. The researcher thus proposes that the reliance on indigenous crops be anchored in community food security, food sovereignty and rural food system perspectives, not negating the negative effects of climate change on food production. The results showed that despite progress made by the state in assisting farmers with agricultural inputs, very little has been achieved in alleviating food insecurity in the dry regions, as indigenous cereal crops continue being pushed to the periphery of the agricultural sector. iii The study concludes by putting forward that addressing the stated challenges could lead to the potential of indigenous cerealcrops potentially increasing the cereal supply for the nation, thus alleviating food security woes as these crops grow favourably even in the most adverse weather conditions and poor topography.
- Full Text:
- Date Issued: 2019
- Authors: Nyathi, Vuyiswa Sandra
- Date: 2019
- Subjects: Food security Farms, Small
- Language: English
- Type: Thesis , Doctoral , PhD (Developmental Studies)
- Identifier: http://hdl.handle.net/10353/17070 , vital:40845
- Description: The study endeavoured to find out how indigenous cereal crops in the form of sorghum, pearl millet and finger millet, popularly known as small grain, would help in increasing cereal production in the dry regions of Zimbabwe so as to alleviate food insecurity. For the past decade the nation’s cereal production has been on the decline with the country having to rely on grain imports from neighbouring countries to prevent hunger. Studies that have been carried out have indicated that these indigenous cereal crops are better suited for semi-arid regions like Matabeleland, used as a case study, where maize has almost always been a failing crop. The study examined representations of smallholder farmers through interviews held with agricultural personnel in Matabeleland North and Matabeleland South Provinces. The study argues that instead of relying on maize only as a staple crop, in the semiarid regions of the country, indigenous cereal crops are suitable alternative staple crops in Zimbabwe. Indications from the findings of the study are that diversification of staple crop production should stress the importance of state mediation, distribution and promotion of indigenous cereal crops. The researcher thus proposes that the reliance on indigenous crops be anchored in community food security, food sovereignty and rural food system perspectives, not negating the negative effects of climate change on food production. The results showed that despite progress made by the state in assisting farmers with agricultural inputs, very little has been achieved in alleviating food insecurity in the dry regions, as indigenous cereal crops continue being pushed to the periphery of the agricultural sector. iii The study concludes by putting forward that addressing the stated challenges could lead to the potential of indigenous cerealcrops potentially increasing the cereal supply for the nation, thus alleviating food security woes as these crops grow favourably even in the most adverse weather conditions and poor topography.
- Full Text:
- Date Issued: 2019
Democracy and party dominance in Kenya and South Africa : a comparative study of the Kenya African National Union and the African National Congres
- Authors: Mwangi, Oscar Gakuo
- Date: 2013-08-15
- Subjects: Kenya African National Union African National Congress Political parties -- South Africa Political parties -- Kenya Democracy -- South Africa Democracy -- Kenya South Africa -- Politics and government Kenya -- Politics and government
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2876 , http://hdl.handle.net/10962/d1008431
- Description: Kenya and South Africa can be described as dominant party systems, under the dominance of the Kenya African National Union CKANU) and the African National Congress CANC) respectively. A dominant party system is in essence a democracy. The spirit of democracy may, however, apparently be contradicted by the weight of party dominance, thus questioning the content of and prospects for democracy under party dominance in both Kenya and South Africa. The study is a comparative analysis of party dominance in Kenya and South Africa. The main objective is to exan1ine the relationship between party dominance and democracy in both countries. It seeks to find out how party dominance is reproducing itself and surviving the post 1990 transition processes in Kenya and South Africa. More importantly, the study also seeks to find out how party dominance impacts upon institutions that support or uphold democratization and subsequently democracy. The findings of the study demonstrate that party dominance has reproduced itself and survived the post-1990 period, and is also impacting upon democratization and democracy. The dominant parties take a similar trajectory in pursuit of dominance over the state and its apparatuses. However, they differ when it comes to their relationship with the civil society. That between KANU and civil society is antagonistic, as the ruling party seeks to augment political power through authoritarian dominance of the latter to, while that of the ANC and civil society is responsive, as the former seeks to enhance political stability in the country. The impact of party dominance upon institutions that support democracy takes similar and different trajectories in both countries. Similarities arise with respect to the detrimental impact upon institutions of the Executive that ensure accountability and transparency, evident in the increasing cases of corruption, nepotism and political patronage appointments. Similarly, there has been a detrimental impact upon the Legislature regarding parliamentary proceedings. Parliamentary committees and opposition parties are being rendered ineffective as organs of ensuring transparency and accountability, and are often subject to delegitimation. The impact of party dominance on the Judiciary, however, differs in both countries. In Kenya, the judiciary continues to suffer from excessive interference from the Executive and the ruling party, whereas in South Africa the judicial system remains largely independent with regard to the application of justice, despite constant criticisms from the dominant party. The study concludes that South Africa is, gradually, going the Kenyan way. If this condition is left unchecked there is the possibility that South Africa could eventually end up a psuedo-democracy like Kenya, where formal democratic political institutions such as multiparty elections, exist to mask the reality of authoritarian dominance. The thesis recommends that strengthening civil society organizations, opposition political parties, and state institutions in both countries to ensure greater accountability and transparency, will reverse this detrimental effect of party dominance. It also recommends meaningful constitutional reforms that will guarantee greater independence of these institutions, and the decentralization of governmental and political power to check and limit the powers of the dominant party. Also recommended are areas for further research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
- Authors: Mwangi, Oscar Gakuo
- Date: 2013-08-15
- Subjects: Kenya African National Union African National Congress Political parties -- South Africa Political parties -- Kenya Democracy -- South Africa Democracy -- Kenya South Africa -- Politics and government Kenya -- Politics and government
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2876 , http://hdl.handle.net/10962/d1008431
- Description: Kenya and South Africa can be described as dominant party systems, under the dominance of the Kenya African National Union CKANU) and the African National Congress CANC) respectively. A dominant party system is in essence a democracy. The spirit of democracy may, however, apparently be contradicted by the weight of party dominance, thus questioning the content of and prospects for democracy under party dominance in both Kenya and South Africa. The study is a comparative analysis of party dominance in Kenya and South Africa. The main objective is to exan1ine the relationship between party dominance and democracy in both countries. It seeks to find out how party dominance is reproducing itself and surviving the post 1990 transition processes in Kenya and South Africa. More importantly, the study also seeks to find out how party dominance impacts upon institutions that support or uphold democratization and subsequently democracy. The findings of the study demonstrate that party dominance has reproduced itself and survived the post-1990 period, and is also impacting upon democratization and democracy. The dominant parties take a similar trajectory in pursuit of dominance over the state and its apparatuses. However, they differ when it comes to their relationship with the civil society. That between KANU and civil society is antagonistic, as the ruling party seeks to augment political power through authoritarian dominance of the latter to, while that of the ANC and civil society is responsive, as the former seeks to enhance political stability in the country. The impact of party dominance upon institutions that support democracy takes similar and different trajectories in both countries. Similarities arise with respect to the detrimental impact upon institutions of the Executive that ensure accountability and transparency, evident in the increasing cases of corruption, nepotism and political patronage appointments. Similarly, there has been a detrimental impact upon the Legislature regarding parliamentary proceedings. Parliamentary committees and opposition parties are being rendered ineffective as organs of ensuring transparency and accountability, and are often subject to delegitimation. The impact of party dominance on the Judiciary, however, differs in both countries. In Kenya, the judiciary continues to suffer from excessive interference from the Executive and the ruling party, whereas in South Africa the judicial system remains largely independent with regard to the application of justice, despite constant criticisms from the dominant party. The study concludes that South Africa is, gradually, going the Kenyan way. If this condition is left unchecked there is the possibility that South Africa could eventually end up a psuedo-democracy like Kenya, where formal democratic political institutions such as multiparty elections, exist to mask the reality of authoritarian dominance. The thesis recommends that strengthening civil society organizations, opposition political parties, and state institutions in both countries to ensure greater accountability and transparency, will reverse this detrimental effect of party dominance. It also recommends meaningful constitutional reforms that will guarantee greater independence of these institutions, and the decentralization of governmental and political power to check and limit the powers of the dominant party. Also recommended are areas for further research. , KMBT_363 , Adobe Acrobat 9.54 Paper Capture Plug-in
- Full Text:
Risk-based assessment of environmental asbestos contamination in the Northern Cape and North West provinces of South Africa
- Authors: Jones, Robert Ryan
- Date: 2011
- Subjects: Asbestos industry -- Health aspects -- South Africa -- Northern Cape Asbestos industry -- Health aspects -- South Africa -- North West Environmental risk assessment -- South Africa-- Northern Cape Environmental risk assessment -- North West Asbestos -- Toxicology -- South Africa -- Northern Cape Asbestos -- Toxicology -- South Africa -- North West Tailings (Metallurgy) -- Waste disposal -- South Africa -- Northern Cape Tailings (Metallurgy) -- Waste disposal -- South Africa -- North West
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4780 , http://hdl.handle.net/10962/d1012612
- Description: The commercial mining of asbestos occurred in four Provinces of South Africa (Northern Cape, North West, Limpopo and Mpumalanga). It was initiated in the late 1800's and lasted for over a hundred years into the beginning of this century. As a producer of amphibole asbestos, South Africa far outpaced every other country being responsible for 97% of global production. The last crocidolite mine closed in 1996 and chrysotile in 2002. Anecdotal information concerning environmental contamination as a result of the former mining activities and the improper disposal of mine waste tailings has been reported by a variety of authors. Few comprehensive or systematic surveys have been conducted to date to document this issue and very little quantifiable research has been completed on the communities located in close proximity to the former mine sites to determine the extent of contamination. In 2004-2006 communities were surveyed within the Northern Cape and North West Provinces to determine the extent and severity of environmental contamination. This research developed and applied a methodology to select those communities suspected of environmental contamination, a targeted survey methodology, and a protocol for rapid sample laboratory analysis. A total of 41 communities were initially predicted by the model to be suspected for environmental asbestos contamination. Based on the inclusion of local knowledge, a final 36 communities were selected for a screening-level field assessment, 34 of which were found to contain environmental asbestos contamination at rates ranging from 20 to 100% of the surveyed locations. A total of 1 843 samples of soil and building material were collected in the screening level assessment. One community (Ga-Mopedi) was selected as being representative of the total cohort and a more detailed house to house survey was completed. A total of 1 486 samples were collected during the detailed survey. Results of the detailed survey revealed 26.2% of the homes were contaminated with asbestos containing soil and/or building material. A theoretical quantitative cumulative exposure assessment was developed to estimate the disease burden within the study area population of 126,130 individuals within the surveyed communities resulting in a predicted range of 25-52.4 excess deaths per year from lung cancer and mesothelioma due solely to environmental exposures to asbestos pollution.
- Full Text:
- Date Issued: 2011
- Authors: Jones, Robert Ryan
- Date: 2011
- Subjects: Asbestos industry -- Health aspects -- South Africa -- Northern Cape Asbestos industry -- Health aspects -- South Africa -- North West Environmental risk assessment -- South Africa-- Northern Cape Environmental risk assessment -- North West Asbestos -- Toxicology -- South Africa -- Northern Cape Asbestos -- Toxicology -- South Africa -- North West Tailings (Metallurgy) -- Waste disposal -- South Africa -- Northern Cape Tailings (Metallurgy) -- Waste disposal -- South Africa -- North West
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4780 , http://hdl.handle.net/10962/d1012612
- Description: The commercial mining of asbestos occurred in four Provinces of South Africa (Northern Cape, North West, Limpopo and Mpumalanga). It was initiated in the late 1800's and lasted for over a hundred years into the beginning of this century. As a producer of amphibole asbestos, South Africa far outpaced every other country being responsible for 97% of global production. The last crocidolite mine closed in 1996 and chrysotile in 2002. Anecdotal information concerning environmental contamination as a result of the former mining activities and the improper disposal of mine waste tailings has been reported by a variety of authors. Few comprehensive or systematic surveys have been conducted to date to document this issue and very little quantifiable research has been completed on the communities located in close proximity to the former mine sites to determine the extent of contamination. In 2004-2006 communities were surveyed within the Northern Cape and North West Provinces to determine the extent and severity of environmental contamination. This research developed and applied a methodology to select those communities suspected of environmental contamination, a targeted survey methodology, and a protocol for rapid sample laboratory analysis. A total of 41 communities were initially predicted by the model to be suspected for environmental asbestos contamination. Based on the inclusion of local knowledge, a final 36 communities were selected for a screening-level field assessment, 34 of which were found to contain environmental asbestos contamination at rates ranging from 20 to 100% of the surveyed locations. A total of 1 843 samples of soil and building material were collected in the screening level assessment. One community (Ga-Mopedi) was selected as being representative of the total cohort and a more detailed house to house survey was completed. A total of 1 486 samples were collected during the detailed survey. Results of the detailed survey revealed 26.2% of the homes were contaminated with asbestos containing soil and/or building material. A theoretical quantitative cumulative exposure assessment was developed to estimate the disease burden within the study area population of 126,130 individuals within the surveyed communities resulting in a predicted range of 25-52.4 excess deaths per year from lung cancer and mesothelioma due solely to environmental exposures to asbestos pollution.
- Full Text:
- Date Issued: 2011
Time series models for paired comparisons
- Authors: Sjolander, Morne Rowan
- Date: 2011
- Subjects: Paired comparisons (Statistics)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10577 , http://hdl.handle.net/10948/d1012858
- Description: The method of paired comparisons is seen as a technique used to rank a set of objects with respect to an abstract or immeasurable property. To do this, the objects get to be compared two at a time. The results are input into a model, resulting in numbers known as weights being assigned to the objects. The weights are then used to rank the objects. The method of paired comparisons was first used for psychometric investigations. Various other applications of the method are also present, for example economic applications, and applications in sports statistics. This study involves taking paired comparison models and making them time-dependent. Not much research has been done in this area. Three new time series models for paired comparisons are created. Simulations are done to support the evidence obtained, and theoretical as well as practical examples are given to illustrate the results and to verify the efficiency of the new models. A literature study is given on the method of paired comparisons, as well as on the areas in which we apply our models. Our first two time series models for paired comparisons are the Linear-Trend Bradley- Terry Model and the Sinusoidal Bradley-Terry Model. We use the maximum likelihood approach to solve these models. We test our models using exact and randomly simulated data for various time periods and various numbers of objects. We adapt the Linear-Trend Bradley-Terry Model and received our third time series model for paired comparisons, the Log Linear-Trend Bradley-Terry Model. The daily maximum and minimum temperatures were received for Port Elizabeth, Uitenhage and Coega for 2005 until 2009. To evaluate the performance of the Linear-Trend Bradley-Terry Model and the Sinusoidal Bradley-Terry Model on estimating missing temperature data, we artificially remove observations of temperature from Coega’s temperature dataset for 2006 until 2008, and use various forms of these models to estimate the missing data points. The exchange rates for 2005 until 2008 between the following currencies: the Rand, Dollar, Euro, Pound and Yen, were obtained and various forms of our Log Linear-Trend Bradley-Terry Model are used to forecast the exchange rate for one day ahead for each month in 2006 until 2008. One of the features of this study is that we apply our time series models for paired comparisons to areas which comprise non-standard paired comparisons; and we want to encourage the use of the method of paired comparisons in a broader sense than what it is traditionally used for. The results of this study can be used in various other areas, like for example, in sports statistics, to rank the strength of sports players and predict their future scores; in Physics, to calculate weather risks of electricity generation, particularly risks related to nuclear power plants, and so forth, as well as in many other areas. It is hoped that this research will open the door to much more research in combining time series analysis with the method of paired comparisons.
- Full Text:
- Date Issued: 2011
- Authors: Sjolander, Morne Rowan
- Date: 2011
- Subjects: Paired comparisons (Statistics)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10577 , http://hdl.handle.net/10948/d1012858
- Description: The method of paired comparisons is seen as a technique used to rank a set of objects with respect to an abstract or immeasurable property. To do this, the objects get to be compared two at a time. The results are input into a model, resulting in numbers known as weights being assigned to the objects. The weights are then used to rank the objects. The method of paired comparisons was first used for psychometric investigations. Various other applications of the method are also present, for example economic applications, and applications in sports statistics. This study involves taking paired comparison models and making them time-dependent. Not much research has been done in this area. Three new time series models for paired comparisons are created. Simulations are done to support the evidence obtained, and theoretical as well as practical examples are given to illustrate the results and to verify the efficiency of the new models. A literature study is given on the method of paired comparisons, as well as on the areas in which we apply our models. Our first two time series models for paired comparisons are the Linear-Trend Bradley- Terry Model and the Sinusoidal Bradley-Terry Model. We use the maximum likelihood approach to solve these models. We test our models using exact and randomly simulated data for various time periods and various numbers of objects. We adapt the Linear-Trend Bradley-Terry Model and received our third time series model for paired comparisons, the Log Linear-Trend Bradley-Terry Model. The daily maximum and minimum temperatures were received for Port Elizabeth, Uitenhage and Coega for 2005 until 2009. To evaluate the performance of the Linear-Trend Bradley-Terry Model and the Sinusoidal Bradley-Terry Model on estimating missing temperature data, we artificially remove observations of temperature from Coega’s temperature dataset for 2006 until 2008, and use various forms of these models to estimate the missing data points. The exchange rates for 2005 until 2008 between the following currencies: the Rand, Dollar, Euro, Pound and Yen, were obtained and various forms of our Log Linear-Trend Bradley-Terry Model are used to forecast the exchange rate for one day ahead for each month in 2006 until 2008. One of the features of this study is that we apply our time series models for paired comparisons to areas which comprise non-standard paired comparisons; and we want to encourage the use of the method of paired comparisons in a broader sense than what it is traditionally used for. The results of this study can be used in various other areas, like for example, in sports statistics, to rank the strength of sports players and predict their future scores; in Physics, to calculate weather risks of electricity generation, particularly risks related to nuclear power plants, and so forth, as well as in many other areas. It is hoped that this research will open the door to much more research in combining time series analysis with the method of paired comparisons.
- Full Text:
- Date Issued: 2011
Catalytic activities of metallophthalocyanines towards detection and transformation of pollutants
- Authors: Agboola, Bolade Oyeyinka
- Date: 2007
- Subjects: Phthalocyanines Electrochemistry Pollutants -- Biodegradation Pollutants -- Measurement
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4427 , http://hdl.handle.net/10962/d1006922
- Description: Syntheses, spectral, electrochemical and spectroelectrochemical studies of new thiol-derivatised MPc complexes were satisfactorily carried out. For the first time, spectroelectrochemistry gave evidence for the formation of Ni²⁺/Ni⁺ process in a NiPc complex. Significant insights as to the nature of Fe⁺Pc and Ni⁺Pc spectra were obtained. Transformations of chlorophenols using chemical and photochemical methods are presented. For cobalt tetrasulphophthalocyanine catalysed oxidation of chlorophenols using hydrogen peroxide as the oxidant, types of oxidation products formed depended on the solvent conditions. Photolysis of aqueous solutions of chlorophenols in the presence of immobilised non-transition metal phthalocyanine photosensitisers onto Amerlite® was carried out. For the first time, MPcS[subscript mix] complexes were immobilised on Amberlite® for use in heterogeneous photocatalysis. Photolysis of the chlorophenols resulted mainly in the formation of chlorobenzoquinone derivatives. The generation of singlet oxygen (¹O₂) by these immobilised MPc photosensitisers was found to play a major role in their photoactivities. Modifications of gold electrodes with the newly synthesised thiol-derivatised MPc complexes via electropolymerisation and SAM techniques are presented. Cyclic voltammetry, impedance spectroscopy (NiPcs only) and spectroelectrochemical techniques (NiPcs only) confirmed that the complexes formed films on gold electrodes. Stable and well packed SAM films as evidenced by the voltammetric characterisation were obtained. For the first time, optimisation of the time for SAM formation based on CV technique was studied. First example of a formation of MnPc-SAM was achieved. Catalytic activities of the NiPc towards chlorophenol depended on the nature of the NiPc in the polymer films and also anti-fouling ability of the films depended on polymer film thickness. The FeTBMPc polymer modified gold electrode showed the best catalytic activity in terms of peak potential, E[subscript p] when compared to reported work in literature for nitrate electrooxidation. Cyclic voltammetry and spectroscopy studies showed that the CoPcs, FePcs and NiPcs catalysed nitrite oxidation involve 2 electrons in total while that of McPcs involve 1 electron. Better catalytic performance towards sulphite electrooxidation were obtained for the CoPcs, FePcs and MnPcs which have metal based redox processes within the range of the sulphite electrooxidation peak while the NiPcs which did not show metal based oxidation reaction performed less.
- Full Text:
- Date Issued: 2007
- Authors: Agboola, Bolade Oyeyinka
- Date: 2007
- Subjects: Phthalocyanines Electrochemistry Pollutants -- Biodegradation Pollutants -- Measurement
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4427 , http://hdl.handle.net/10962/d1006922
- Description: Syntheses, spectral, electrochemical and spectroelectrochemical studies of new thiol-derivatised MPc complexes were satisfactorily carried out. For the first time, spectroelectrochemistry gave evidence for the formation of Ni²⁺/Ni⁺ process in a NiPc complex. Significant insights as to the nature of Fe⁺Pc and Ni⁺Pc spectra were obtained. Transformations of chlorophenols using chemical and photochemical methods are presented. For cobalt tetrasulphophthalocyanine catalysed oxidation of chlorophenols using hydrogen peroxide as the oxidant, types of oxidation products formed depended on the solvent conditions. Photolysis of aqueous solutions of chlorophenols in the presence of immobilised non-transition metal phthalocyanine photosensitisers onto Amerlite® was carried out. For the first time, MPcS[subscript mix] complexes were immobilised on Amberlite® for use in heterogeneous photocatalysis. Photolysis of the chlorophenols resulted mainly in the formation of chlorobenzoquinone derivatives. The generation of singlet oxygen (¹O₂) by these immobilised MPc photosensitisers was found to play a major role in their photoactivities. Modifications of gold electrodes with the newly synthesised thiol-derivatised MPc complexes via electropolymerisation and SAM techniques are presented. Cyclic voltammetry, impedance spectroscopy (NiPcs only) and spectroelectrochemical techniques (NiPcs only) confirmed that the complexes formed films on gold electrodes. Stable and well packed SAM films as evidenced by the voltammetric characterisation were obtained. For the first time, optimisation of the time for SAM formation based on CV technique was studied. First example of a formation of MnPc-SAM was achieved. Catalytic activities of the NiPc towards chlorophenol depended on the nature of the NiPc in the polymer films and also anti-fouling ability of the films depended on polymer film thickness. The FeTBMPc polymer modified gold electrode showed the best catalytic activity in terms of peak potential, E[subscript p] when compared to reported work in literature for nitrate electrooxidation. Cyclic voltammetry and spectroscopy studies showed that the CoPcs, FePcs and NiPcs catalysed nitrite oxidation involve 2 electrons in total while that of McPcs involve 1 electron. Better catalytic performance towards sulphite electrooxidation were obtained for the CoPcs, FePcs and MnPcs which have metal based redox processes within the range of the sulphite electrooxidation peak while the NiPcs which did not show metal based oxidation reaction performed less.
- Full Text:
- Date Issued: 2007
Operating in turbulent times: an investigation into the characteristics of strategic flexibility exhibited by South African export companies
- Authors: Skae, Frederick Owen
- Date: 1989
- Subjects: Export trading companies -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1159 , http://hdl.handle.net/10962/d1001626
- Description: Broadly stated, the major objective of this study was to investigate the extent to which South African export companies exhibited characteristics of strategic flexibility, which is seen to be the most viable strategic option for a firm operating within a turbulent environment. This entailed:- (1) Determining the degree of environmental turbulence as perceived by South African export companies and identifying the most important elements of the external environment as perceived by these companies. (2) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies facing environments of either low, medium or high turbulence. (3) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies of different size. In order to elicit this information, 1361 questionnaires were posted to the managing directors of export firms who were members of the South African Foreign Trade Organization. The major findings of this study indicate that:- (1) Political elements of the remote environment contribute most to environmental turbulence. (2) Respondents identified economic elements as being the most important in terms of their potential impact on the long term profitability of the firm. (3) Although at present the majority of the firms surveyed were classified as operatIng in medium levels of turbulence, in the future they perceive the external environment as becoming very turbulent. (4) Generally speaking, the firms surveyed are ill-equipped to operate in a turbulent environment as they displayed signs of inflexibility in certain key aspects of their business. In this regard, particular mention must be made of their decision-making processes, the extent to which they had specialist planners, the techniques used to identify future trends in the environment, the extent to which computer technology was utilised in the firm and their structure. (5) Finally, the results do not generally support the view that a relationship exists between the perceived degree of turbulence in the environment and the extent to which strategic flexibility exists in the firm. Often, however, the size of tne firm was more of a determining factor on the components of strategic flexibility than the degree of turbulence in the environment. In this regard, particular mention must be made of the impact of size on the planning processes of the firm, the techniques used to monitor trends in the environment and the emphasis placed on management development and training.
- Full Text:
- Date Issued: 1989
- Authors: Skae, Frederick Owen
- Date: 1989
- Subjects: Export trading companies -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1159 , http://hdl.handle.net/10962/d1001626
- Description: Broadly stated, the major objective of this study was to investigate the extent to which South African export companies exhibited characteristics of strategic flexibility, which is seen to be the most viable strategic option for a firm operating within a turbulent environment. This entailed:- (1) Determining the degree of environmental turbulence as perceived by South African export companies and identifying the most important elements of the external environment as perceived by these companies. (2) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies facing environments of either low, medium or high turbulence. (3) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies of different size. In order to elicit this information, 1361 questionnaires were posted to the managing directors of export firms who were members of the South African Foreign Trade Organization. The major findings of this study indicate that:- (1) Political elements of the remote environment contribute most to environmental turbulence. (2) Respondents identified economic elements as being the most important in terms of their potential impact on the long term profitability of the firm. (3) Although at present the majority of the firms surveyed were classified as operatIng in medium levels of turbulence, in the future they perceive the external environment as becoming very turbulent. (4) Generally speaking, the firms surveyed are ill-equipped to operate in a turbulent environment as they displayed signs of inflexibility in certain key aspects of their business. In this regard, particular mention must be made of their decision-making processes, the extent to which they had specialist planners, the techniques used to identify future trends in the environment, the extent to which computer technology was utilised in the firm and their structure. (5) Finally, the results do not generally support the view that a relationship exists between the perceived degree of turbulence in the environment and the extent to which strategic flexibility exists in the firm. Often, however, the size of tne firm was more of a determining factor on the components of strategic flexibility than the degree of turbulence in the environment. In this regard, particular mention must be made of the impact of size on the planning processes of the firm, the techniques used to monitor trends in the environment and the emphasis placed on management development and training.
- Full Text:
- Date Issued: 1989
Witwatersrand genesis: a comparative study of some early gold mining companies, 1886-1894
- Authors: Webb, Arthur (Arthur C M)
- Date: 1982
- Subjects: Gold mines and mining -- South Africa -- History Gold mines and mining -- South Africa -- Witwatersrand -- History Ferreira Gold Mining Company (Firm) Witwatersrand Gold Mining Company (Firm) Simmer and Jack Gold Mining Company (Firm) Wemmer Gold Mining Company (Firm)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:1029 , http://hdl.handle.net/10962/d1003725
- Description: Preface: For anyone standing on the ridge of the Witwatersrand on a spring day in September 1886 the sight immediately to the south represented a hive of activity and hope. Nearly a hundred years later ample evidence stretches away on both sides of the watershed to confirm the fulfilment of those early sentiments. It is, nevertheless, all too easy to ignore the struggles and failures which marked the beginnings of the world's greatest gold field in the light of its subsequent abundant success. Only when attention is turned to the individual companies formed to exploit the discovery does the true picture emerge of the lack of adequate technological and managerial knowledge amongst the early pioneers and of the financial frailty of their companies. The object of this thesis is to shed light on these beginnings by reviewing the histories of four of the earliest companies established to work the main reef. The approach adopted is to scrutinize the material available with a view to determining the motivations and actions of the managements of the various companies with regard to their economic environment, whether within or without the individual company. Clearly, the availability of information is a major determinant of the success of any such venture and this was particularly so in the case of the companies considered. With the exception of the Barlow Rand Limited holding of the H. Eckstein and Company Archives, which offers an integral coverage of that firm's dealings with the emerging industry, and which is certainly the most comprehensive source of information available to the researcher, little material relating to specific gold mining companies has survived. Under these circumstances it was necessary to rely heavily for information on the local press. These newspapers proved an invaluable source in this regard. As a mining camp with a limited capacity for generating newsworthy incidents, the newspapers of early Johannesburg found an eager readership for information about the industry which lay at the heart of the community. For their part, the managements of the various mining companies found in the pages of the local press an outlet for intelligence both true and false; the press was a useful vehicle for the publication of directors' and annual reports to meet a wider audience, but similarly it could be and was used to disseminate 'spectacular' reports calculated to influence the status of a company's stock on the local share market. As a research source the press has thus to be approached with caution but its value, if the warning is heeded, is in no way diminished. Beyond these two sources the next most valuable accumulation of data on the early industry is "The Gold Fields Collection" housed in the Cory Library for Historical Research at Rhodes University. As a collection it is far from complete and it is to be hoped that the donors will in future see fit to augment it with further material as this becomes available. It neverthess proved an invaluable source for the investigation of at least one of the companies of the study and for a general background to the industry.
- Full Text:
- Date Issued: 1982
- Authors: Webb, Arthur (Arthur C M)
- Date: 1982
- Subjects: Gold mines and mining -- South Africa -- History Gold mines and mining -- South Africa -- Witwatersrand -- History Ferreira Gold Mining Company (Firm) Witwatersrand Gold Mining Company (Firm) Simmer and Jack Gold Mining Company (Firm) Wemmer Gold Mining Company (Firm)
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:1029 , http://hdl.handle.net/10962/d1003725
- Description: Preface: For anyone standing on the ridge of the Witwatersrand on a spring day in September 1886 the sight immediately to the south represented a hive of activity and hope. Nearly a hundred years later ample evidence stretches away on both sides of the watershed to confirm the fulfilment of those early sentiments. It is, nevertheless, all too easy to ignore the struggles and failures which marked the beginnings of the world's greatest gold field in the light of its subsequent abundant success. Only when attention is turned to the individual companies formed to exploit the discovery does the true picture emerge of the lack of adequate technological and managerial knowledge amongst the early pioneers and of the financial frailty of their companies. The object of this thesis is to shed light on these beginnings by reviewing the histories of four of the earliest companies established to work the main reef. The approach adopted is to scrutinize the material available with a view to determining the motivations and actions of the managements of the various companies with regard to their economic environment, whether within or without the individual company. Clearly, the availability of information is a major determinant of the success of any such venture and this was particularly so in the case of the companies considered. With the exception of the Barlow Rand Limited holding of the H. Eckstein and Company Archives, which offers an integral coverage of that firm's dealings with the emerging industry, and which is certainly the most comprehensive source of information available to the researcher, little material relating to specific gold mining companies has survived. Under these circumstances it was necessary to rely heavily for information on the local press. These newspapers proved an invaluable source in this regard. As a mining camp with a limited capacity for generating newsworthy incidents, the newspapers of early Johannesburg found an eager readership for information about the industry which lay at the heart of the community. For their part, the managements of the various mining companies found in the pages of the local press an outlet for intelligence both true and false; the press was a useful vehicle for the publication of directors' and annual reports to meet a wider audience, but similarly it could be and was used to disseminate 'spectacular' reports calculated to influence the status of a company's stock on the local share market. As a research source the press has thus to be approached with caution but its value, if the warning is heeded, is in no way diminished. Beyond these two sources the next most valuable accumulation of data on the early industry is "The Gold Fields Collection" housed in the Cory Library for Historical Research at Rhodes University. As a collection it is far from complete and it is to be hoped that the donors will in future see fit to augment it with further material as this becomes available. It neverthess proved an invaluable source for the investigation of at least one of the companies of the study and for a general background to the industry.
- Full Text:
- Date Issued: 1982
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