In vitro susceptibility of Staphylococcus aureus to porphyrin-silver mediated photodynamic antimicrobial chemotherapy
- Authors: Shabangu, Samuel Malewa
- Date: 2020
- Subjects: Porphyrins , Nanoparticles , Photochemotherapy , Drug resistance in microorganisms , Staphylococcus aureus
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/167476 , vital:41484
- Description: This work reports on the syntheses and characterization of symmetrical and unsymmetrical porphyrin complexes namely, 5,10,15,20-tetra(4-pyridyl)-porphyrinato zinc(II) (1), 5,10,15,20-tetrathienyl porphyrinato zinc(II) (2), 5-(4-hydroxyphenyl)-10, 15, 20-tris(2-thienyl) porphyrinato zinc(II) (3), 5-(4-carboxyphenyl)-10,15,20-tris(pentafluorophenyl)- porphyrinato zinc(II) (4), 5-(4-carboxyphenyl)-10,15,20-triphenyl-porphyrinato zinc(II) (5) and 5-(4-carboxyphenyl)-10, 15, 20-tris(2-thienyl)-porphyrinato zinc(II) (6). The synthesis of silver nanoparticles (AgNPs) was also undertaken in this research work. Complexes 1, 2, 3 and 6 were linked to oleic acid/oleylamine functionalized nanoparticles via self-assembly and 4-6 were linked via covalent interaction through an amide bond to glutathione capped AgNPs. The effect of nature of bond along with symmetry were investigated, of interest were the five membered thienyl substituents. The photophysical and photochemical behaviour of the complexes and their conjugates with AgNPs were investigated in dimethylformamide. The porphyrin and AgNPs conjugates afforded an increase in singlet oxygen quantum yield. Complexes 1-6 and their conjugates were used for photodynamic antimicrobial chemotherapy of Staphylococcus aureus. The antimicrobial studies were done in two different concentrations of 0.36 and 2.0 μg/mL. The thienyl substituted porphyrin complexes and their conjugates gave better photodynamic activity as compared to phenyl analogues
- Full Text:
- Authors: Shabangu, Samuel Malewa
- Date: 2020
- Subjects: Porphyrins , Nanoparticles , Photochemotherapy , Drug resistance in microorganisms , Staphylococcus aureus
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/167476 , vital:41484
- Description: This work reports on the syntheses and characterization of symmetrical and unsymmetrical porphyrin complexes namely, 5,10,15,20-tetra(4-pyridyl)-porphyrinato zinc(II) (1), 5,10,15,20-tetrathienyl porphyrinato zinc(II) (2), 5-(4-hydroxyphenyl)-10, 15, 20-tris(2-thienyl) porphyrinato zinc(II) (3), 5-(4-carboxyphenyl)-10,15,20-tris(pentafluorophenyl)- porphyrinato zinc(II) (4), 5-(4-carboxyphenyl)-10,15,20-triphenyl-porphyrinato zinc(II) (5) and 5-(4-carboxyphenyl)-10, 15, 20-tris(2-thienyl)-porphyrinato zinc(II) (6). The synthesis of silver nanoparticles (AgNPs) was also undertaken in this research work. Complexes 1, 2, 3 and 6 were linked to oleic acid/oleylamine functionalized nanoparticles via self-assembly and 4-6 were linked via covalent interaction through an amide bond to glutathione capped AgNPs. The effect of nature of bond along with symmetry were investigated, of interest were the five membered thienyl substituents. The photophysical and photochemical behaviour of the complexes and their conjugates with AgNPs were investigated in dimethylformamide. The porphyrin and AgNPs conjugates afforded an increase in singlet oxygen quantum yield. Complexes 1-6 and their conjugates were used for photodynamic antimicrobial chemotherapy of Staphylococcus aureus. The antimicrobial studies were done in two different concentrations of 0.36 and 2.0 μg/mL. The thienyl substituted porphyrin complexes and their conjugates gave better photodynamic activity as compared to phenyl analogues
- Full Text:
Machine learning methods for calibrating radio interferometric data
- Authors: Zitha, Simphiwe Nhlanhla
- Date: 2019
- Subjects: Calibration , Radio astronomy -- Data processing , Radio astronomy -- South Africa , Karoo Array Telescope (South Africa) , Radio telescopes -- South Africa , Common Astronomy Software Application (Computer software)
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/97096 , vital:31398
- Description: The applications of machine learning have created an opportunity to deal with complex problems currently encountered in radio astronomy data processing. Calibration is one of the most important data processing steps required to produce high dynamic range images. This process involves the determination of calibration parameters, both instrumental and astronomical, to correct the collected data. Typically, astronomers use a package such as Common Astronomy Software Applications (CASA) to compute the gain solutions based on regular observations of a known calibrator source. In this work we present applications of machine learning to first generation calibration (1GC), using the KAT-7 telescope environmental and pointing sensor data recorded during observations. Applying machine learning to 1GC, as opposed to calculating the gain solutions in CASA, has shown evidence of reducing computation, as well as accurately predict the 1GC gain solutions representing the behaviour of the antenna during an observation. These methods are computationally less expensive, however they have not fully learned to generalise in predicting accurate 1GC solutions by looking at environmental and pointing sensors. We call this multi-output regression model ZCal, which is based on random forest, decision trees, extremely randomized trees and K-nearest neighbor algorithms. The prediction error obtained during the testing of our model on testing data is ≈ 0.01 < rmse < 0.09 for gain amplitude per antenna, and 0.2 rad < rmse <0.5 rad for gain phase. This shows that the instrumental parameters used to train our model more strongly correlate with gain amplitude effects than phase.
- Full Text:
- Authors: Zitha, Simphiwe Nhlanhla
- Date: 2019
- Subjects: Calibration , Radio astronomy -- Data processing , Radio astronomy -- South Africa , Karoo Array Telescope (South Africa) , Radio telescopes -- South Africa , Common Astronomy Software Application (Computer software)
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/97096 , vital:31398
- Description: The applications of machine learning have created an opportunity to deal with complex problems currently encountered in radio astronomy data processing. Calibration is one of the most important data processing steps required to produce high dynamic range images. This process involves the determination of calibration parameters, both instrumental and astronomical, to correct the collected data. Typically, astronomers use a package such as Common Astronomy Software Applications (CASA) to compute the gain solutions based on regular observations of a known calibrator source. In this work we present applications of machine learning to first generation calibration (1GC), using the KAT-7 telescope environmental and pointing sensor data recorded during observations. Applying machine learning to 1GC, as opposed to calculating the gain solutions in CASA, has shown evidence of reducing computation, as well as accurately predict the 1GC gain solutions representing the behaviour of the antenna during an observation. These methods are computationally less expensive, however they have not fully learned to generalise in predicting accurate 1GC solutions by looking at environmental and pointing sensors. We call this multi-output regression model ZCal, which is based on random forest, decision trees, extremely randomized trees and K-nearest neighbor algorithms. The prediction error obtained during the testing of our model on testing data is ≈ 0.01 < rmse < 0.09 for gain amplitude per antenna, and 0.2 rad < rmse <0.5 rad for gain phase. This shows that the instrumental parameters used to train our model more strongly correlate with gain amplitude effects than phase.
- Full Text:
‘That mountain cannot be beautiful for nothing’: Zakes Mda’s aesthetics of liberation
- Dilinga, Siyamthanda Iribagiza
- Authors: Dilinga, Siyamthanda Iribagiza
- Date: 2019
- Subjects: Mda, Zakes -- Criticism and interpretation , South African fiction (English) -- History and criticism , South Africa -- In literature
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/70452 , vital:29662
- Description: Zakes Mda is a prominent post-apartheid black South African novelist whose style has been described as experimental. He also wrote plays intended to ‘rally people to action’ during the apartheid years. The changes in the political and social situation in South Africa since 1994 have had significant implications for those writers and artists who produced protest literature and art. The changes in Mda’s own practice and approach to art are themselves quite telling. His experimental novels place him among those African artists pioneering a new chapter for black South African art and the self-reflexive nature of his novels suggest that he is aware of the fact and is consciously forming and reforming his ideas about what it means to be an artist in post-apartheid South Africa. This study will unpack the role of the artist and the function of art in the becoming new South Africa as represented in Zakes Mda’s novels, thereby hypothesizing Mda’s aesthetic philosophy, as may be deduced from his practice, for what an African artist and art should be. This will be done first by locating Mda in the debates around art and literature within the sociopolitical context of a South Africa in transition. Despite the fact that when it comes to public action in the post-apartheid situation, Mda distinguishes between his own role in society as an artist who is a social activist and the role intended for his work, his own novels reveal a desire for the artefact (or artwork) to have a developmental, educational or conscientizing function. This is evident in representations of the effects of art in what this study proposes to be his extended South African black Kunstlerroman, which spans three novels. It is also demonstrated in his ekphrastic novel, The Madonna of Excelsior, in which visual art is interpreted in the process of description, thereby educating the reader. Not only that, but the reader is made into an ‘almost viewer’ and taught how to ‘see’ art. What emerges in the process of this study is Mda’s aesthetic philosophy or what may be termed his ‘aesthetics of liberation’ concerning the role of the artist in post-apartheid South Africa, a suitable African audience and how art works theoretically, as expressed through his fiction.
- Full Text:
- Authors: Dilinga, Siyamthanda Iribagiza
- Date: 2019
- Subjects: Mda, Zakes -- Criticism and interpretation , South African fiction (English) -- History and criticism , South Africa -- In literature
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/70452 , vital:29662
- Description: Zakes Mda is a prominent post-apartheid black South African novelist whose style has been described as experimental. He also wrote plays intended to ‘rally people to action’ during the apartheid years. The changes in the political and social situation in South Africa since 1994 have had significant implications for those writers and artists who produced protest literature and art. The changes in Mda’s own practice and approach to art are themselves quite telling. His experimental novels place him among those African artists pioneering a new chapter for black South African art and the self-reflexive nature of his novels suggest that he is aware of the fact and is consciously forming and reforming his ideas about what it means to be an artist in post-apartheid South Africa. This study will unpack the role of the artist and the function of art in the becoming new South Africa as represented in Zakes Mda’s novels, thereby hypothesizing Mda’s aesthetic philosophy, as may be deduced from his practice, for what an African artist and art should be. This will be done first by locating Mda in the debates around art and literature within the sociopolitical context of a South Africa in transition. Despite the fact that when it comes to public action in the post-apartheid situation, Mda distinguishes between his own role in society as an artist who is a social activist and the role intended for his work, his own novels reveal a desire for the artefact (or artwork) to have a developmental, educational or conscientizing function. This is evident in representations of the effects of art in what this study proposes to be his extended South African black Kunstlerroman, which spans three novels. It is also demonstrated in his ekphrastic novel, The Madonna of Excelsior, in which visual art is interpreted in the process of description, thereby educating the reader. Not only that, but the reader is made into an ‘almost viewer’ and taught how to ‘see’ art. What emerges in the process of this study is Mda’s aesthetic philosophy or what may be termed his ‘aesthetics of liberation’ concerning the role of the artist in post-apartheid South Africa, a suitable African audience and how art works theoretically, as expressed through his fiction.
- Full Text:
An exploratory study of barriers and enablers of strategy execution in the Eastern Cape Department of Education in South Africa
- Authors: Vena, Nomava Vinolia
- Date: 2018
- Subjects: Strategic planning South Africa Eastern Cape , Business planning South Africa Eastern Cape , Public administration South Africa Eastern Cape , Corporate governance South Africa Eastern Cape , Government accountability South Africa Eastern Cape , South Africa. Department of Education
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/63649 , vital:28465
- Description: Effective strategy execution is very important for the achievement of an organisation’s goals. Because it is a difficult task to translate a strategy into action, itis imperative for leadership to prioritize its strategic plan to ensure its success. The purpose of this study is to identify barriers and enablers of strategy execution in Basic Education in the Eastern Cape; its focus is on strategic goal number six: “Efficient administration ensured through good corporate governance and management”. The effectiveness of the Eastern Cape Department of Education (ECDoE) is measured by its service delivery, how strategy is executed in providing quality education. These are guided by the norms and standards like the National Education Policy Act: Norms and Standards for educators, as set by the National Department of Basic Education and the Treasury Acts. The motivation for the study was the Department’s poor performance as reported by the Auditor General (AG) in his 2015 audit report, that there has been a lack of good governance and accountability in the ECDoE. The study is qualitative: a sample of twenty-five (25) ECDoE senior managers were interviewed as the custodians of the execution of the strategic plan. Purposive sampling method selected the twenty-five from a total of forty-five (45) senior managers, some of whom were in Head Office and some in the twenty-three (23) districts. Data was collected through questionnaires and interviews and responses were captured on Excel Spreadsheet, and analysed with the Thematic Analysis. Major findings relating to barriers were on Human Resource Management, Poor Leadership, Resourcing (Tools of Trade), Improper Budgeting Systems, Poor Communication, and Organisational Structure. Some variables were interchangeably identified both as barriers and enablers, such as budgeting and resourcing. There were many recommendations, but for this study one, the Finance Section, will suffice: and that is that the Finance Section should analyse each directorate’s spending for each year before the new budget is allocated.
- Full Text:
- Authors: Vena, Nomava Vinolia
- Date: 2018
- Subjects: Strategic planning South Africa Eastern Cape , Business planning South Africa Eastern Cape , Public administration South Africa Eastern Cape , Corporate governance South Africa Eastern Cape , Government accountability South Africa Eastern Cape , South Africa. Department of Education
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/63649 , vital:28465
- Description: Effective strategy execution is very important for the achievement of an organisation’s goals. Because it is a difficult task to translate a strategy into action, itis imperative for leadership to prioritize its strategic plan to ensure its success. The purpose of this study is to identify barriers and enablers of strategy execution in Basic Education in the Eastern Cape; its focus is on strategic goal number six: “Efficient administration ensured through good corporate governance and management”. The effectiveness of the Eastern Cape Department of Education (ECDoE) is measured by its service delivery, how strategy is executed in providing quality education. These are guided by the norms and standards like the National Education Policy Act: Norms and Standards for educators, as set by the National Department of Basic Education and the Treasury Acts. The motivation for the study was the Department’s poor performance as reported by the Auditor General (AG) in his 2015 audit report, that there has been a lack of good governance and accountability in the ECDoE. The study is qualitative: a sample of twenty-five (25) ECDoE senior managers were interviewed as the custodians of the execution of the strategic plan. Purposive sampling method selected the twenty-five from a total of forty-five (45) senior managers, some of whom were in Head Office and some in the twenty-three (23) districts. Data was collected through questionnaires and interviews and responses were captured on Excel Spreadsheet, and analysed with the Thematic Analysis. Major findings relating to barriers were on Human Resource Management, Poor Leadership, Resourcing (Tools of Trade), Improper Budgeting Systems, Poor Communication, and Organisational Structure. Some variables were interchangeably identified both as barriers and enablers, such as budgeting and resourcing. There were many recommendations, but for this study one, the Finance Section, will suffice: and that is that the Finance Section should analyse each directorate’s spending for each year before the new budget is allocated.
- Full Text:
Taxation of non-resident digital companies providing services in South Africa
- Authors: Shumba, Marilyn Tatenda
- Date: 2018
- Subjects: Electronic commerce Taxation Law and legislation South Africa , Value-added tax South Africa , Organisation for Economic Co-operation and Development , Taxation Law and legislation South Africa , Business enterprises, Foreign Taxation Law and legislation South Africa
- Language: English
- Type: text , Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/61680 , vital:28048
- Description: The role played by electronic commerce has increased in recent years and continues to increase. Due to this increase in the buying and selling of digital goods and services, revenue authorities have had to recognise that the existing taxation laws do not adequately tax the digital economy. The goal of this research was to establish how South Africa could amend its fiscal legislation in order to adequately tax the digital economy. The Organisation for Economic Co-Operation and Development (OECD) has been the leader in addressing the challenges posed by the digital economy. The thesis therefore focused on the recommendations by the OECD on how to tax the digital economy and relevant recommendations for South were adopted in this thesis, based on the work of the OECD. The main focus of these recommendations was on implementing the International VAT/GST Guidelines that were drafted by the OECD. The thesis also focused on the progress made by New Zealand with regard to taxing of the digital economy. New Zealand has a similar taxation system to South Africa so that the progress made there was relevant in the South African context. Recommendations were also made, based on the proposals by the New Zealand revenue authority that South Africa could adopt in taxing the digital economy. The main focus of these recommendations was lowering the Value-Added Tax (VAT) registration threshold for non-resident suppliers of electronic services and enacting legislation to provide for registration of an electronic marketplace for VAT purposes, instead of an individual supplier.
- Full Text:
- Authors: Shumba, Marilyn Tatenda
- Date: 2018
- Subjects: Electronic commerce Taxation Law and legislation South Africa , Value-added tax South Africa , Organisation for Economic Co-operation and Development , Taxation Law and legislation South Africa , Business enterprises, Foreign Taxation Law and legislation South Africa
- Language: English
- Type: text , Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/61680 , vital:28048
- Description: The role played by electronic commerce has increased in recent years and continues to increase. Due to this increase in the buying and selling of digital goods and services, revenue authorities have had to recognise that the existing taxation laws do not adequately tax the digital economy. The goal of this research was to establish how South Africa could amend its fiscal legislation in order to adequately tax the digital economy. The Organisation for Economic Co-Operation and Development (OECD) has been the leader in addressing the challenges posed by the digital economy. The thesis therefore focused on the recommendations by the OECD on how to tax the digital economy and relevant recommendations for South were adopted in this thesis, based on the work of the OECD. The main focus of these recommendations was on implementing the International VAT/GST Guidelines that were drafted by the OECD. The thesis also focused on the progress made by New Zealand with regard to taxing of the digital economy. New Zealand has a similar taxation system to South Africa so that the progress made there was relevant in the South African context. Recommendations were also made, based on the proposals by the New Zealand revenue authority that South Africa could adopt in taxing the digital economy. The main focus of these recommendations was lowering the Value-Added Tax (VAT) registration threshold for non-resident suppliers of electronic services and enacting legislation to provide for registration of an electronic marketplace for VAT purposes, instead of an individual supplier.
- Full Text:
The relationship between authentic leadership and employee performance
- Authors: Petzer, Liane
- Date: 2018
- Subjects: Authentic leadership , Positive psychology , Employee motivation -- South Africa , Employees -- Attitudes , Job satisfaction -- South Africa , Employees -- Rating of -- South Africa , Financial services industry -- South Africa
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/59467 , vital:27613
- Description: The impact of a leader on his or her followers has been a topic of much research and therefore organizations, including the financial services sector in South Africa, are placing more and more emphasis on what this leadership construct looks like. Research suggests that Authentic Leadership might be a new kind of leadership approach that the world is looking for. This study aims to establish the possible relationship between an authentic leader and the impact the leader’s behaviour has on the performance of his or her employee. The study further attempts to establish if satisfaction can play a mediating role in the relationship between authentic leadership and the performance of an employee. The research used two established research instruments, namely the Authentic Leadership Questionnaire (ALQ), as well as a section of Freese and Schalk’s (2008) psychological contract questionnaire relating to satisfaction specifically. Respondents were also requested to indicate their most recent performance rating. The study was conducted within the financial sector based in the Eastern and Southern Cape with a total population of 1077 employees across all business units, job grades, race, age, education and gender. The study established a significant positive relationship between authentic leadership and employee performance. A further significant positive relationship was established between authentic leadership and satisfaction. However, no relationship could be established between satisfaction and performance, thereby indicating that satisfaction was not a mediator of the relationship between authentic leadership and employee performance. In conclusion, recommendations for management practice and for further research are made.
- Full Text:
- Authors: Petzer, Liane
- Date: 2018
- Subjects: Authentic leadership , Positive psychology , Employee motivation -- South Africa , Employees -- Attitudes , Job satisfaction -- South Africa , Employees -- Rating of -- South Africa , Financial services industry -- South Africa
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/59467 , vital:27613
- Description: The impact of a leader on his or her followers has been a topic of much research and therefore organizations, including the financial services sector in South Africa, are placing more and more emphasis on what this leadership construct looks like. Research suggests that Authentic Leadership might be a new kind of leadership approach that the world is looking for. This study aims to establish the possible relationship between an authentic leader and the impact the leader’s behaviour has on the performance of his or her employee. The study further attempts to establish if satisfaction can play a mediating role in the relationship between authentic leadership and the performance of an employee. The research used two established research instruments, namely the Authentic Leadership Questionnaire (ALQ), as well as a section of Freese and Schalk’s (2008) psychological contract questionnaire relating to satisfaction specifically. Respondents were also requested to indicate their most recent performance rating. The study was conducted within the financial sector based in the Eastern and Southern Cape with a total population of 1077 employees across all business units, job grades, race, age, education and gender. The study established a significant positive relationship between authentic leadership and employee performance. A further significant positive relationship was established between authentic leadership and satisfaction. However, no relationship could be established between satisfaction and performance, thereby indicating that satisfaction was not a mediator of the relationship between authentic leadership and employee performance. In conclusion, recommendations for management practice and for further research are made.
- Full Text:
Witches & villains: the nasty tales
- Authors: Dalldorf, Tamaryn
- Date: 2018
- Subjects: South African fiction (English) -- 21st century , Short stories, South African (English) -- 21st century , Fairy tales -- 21st century
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/63087 , vital:28362
- Description: My thesis compromises a variety of short stories which are modern re-writes of dark fairy tales. Fairy Tales often explore the dark side of human nature and in these stories I focus on the voices of female villains and the strange psychology which drives them. I find Fairy Tales absorbing because they reveal the vulnerabilities, dreams and fears of the human consciousness. My stories contain some satirical expositions of human nature and society. My influences are the anthology of short stories, “My mother She Killed Me and My Father He Ate Me”, The Grimm Fairy Tales (original) and The Fairy Tales of Charles Perrault as well as the writing of Horacio Moya, Angela Carter and Alissa Nutting for their dark satire and mockery of social eccentricities. Kate Bernheimer’s “Form is Fairy Tale and Fairy Tale is Form” is very influential in terms of the style it recommends in writing such as: “every day magic”, “flatness” (a form of narration), abstraction and intuitive logic.
- Full Text:
- Authors: Dalldorf, Tamaryn
- Date: 2018
- Subjects: South African fiction (English) -- 21st century , Short stories, South African (English) -- 21st century , Fairy tales -- 21st century
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/63087 , vital:28362
- Description: My thesis compromises a variety of short stories which are modern re-writes of dark fairy tales. Fairy Tales often explore the dark side of human nature and in these stories I focus on the voices of female villains and the strange psychology which drives them. I find Fairy Tales absorbing because they reveal the vulnerabilities, dreams and fears of the human consciousness. My stories contain some satirical expositions of human nature and society. My influences are the anthology of short stories, “My mother She Killed Me and My Father He Ate Me”, The Grimm Fairy Tales (original) and The Fairy Tales of Charles Perrault as well as the writing of Horacio Moya, Angela Carter and Alissa Nutting for their dark satire and mockery of social eccentricities. Kate Bernheimer’s “Form is Fairy Tale and Fairy Tale is Form” is very influential in terms of the style it recommends in writing such as: “every day magic”, “flatness” (a form of narration), abstraction and intuitive logic.
- Full Text:
A case study investigation into the utility of baseline data versus normative data using a computer-based concussion management programme
- Authors: Mitchell, Julia
- Date: 2005
- Subjects: Brain -- Concussion , Neuropsychological tests , Sports injuries -- Psychological aspects , Head -- Wounds and injuries -- Complications
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3021 , http://hdl.handle.net/10962/d1002530 , Brain -- Concussion , Neuropsychological tests , Sports injuries -- Psychological aspects , Head -- Wounds and injuries -- Complications
- Description: Neuropsychological testing is recognised as one of the cornerstones of concussion evaluation, contributing significantly to both an understanding of the injury as well as management of the recovery process. Despite the high incidence of concussion at school level, traditional paper-and-pencil neuropsychological testing has generally been absent from school concussion management programmes, largely due to time and cost constraints. Now, the recent development of computerised neuropsychological testing is providing the opportunity for including neurocognitive assessment in this process. The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a valid and reliable instrument of this type and normed on 13 - 18 year old North American high school athletes, as well as adult groups. The current recommendation is that athletes are baselined preseason in order to provide an individualised comparative level against which to monitor recovery and provide return-to-play recommendations. This in itself is quite a cumbersome process, thus the present study set out to ascertain whether baseline testing of all athletes is necessary, or whether the use of US or SA normative data alone would provide an appropriate standard against which to interpret the postinjury scores. From a leading South African rugby playing school, the 1st and 2nd rugby teams, (16 - 18 years) were baselined using ImPACT. Three athletes, who were subsequently referred with concussion during the rugby season, were followed up with serial testing on ImPACT. An analysis of the follow up scores was conducted to chart the athletes' recovery process, in relation to the athletes own baseline scores (using US and SA reliable change indices) and age appropriate US and SA normative ranges. The relative utility of individual baselines scores versus these normative ranges was then critically evaluated. It was concluded that a combination of both baseline and normative data provided optimal management of the athlete, with the methods complementing each other in the interpretation of post-injury results. Overall, the SA normative ranges seemed to provide slightly better management guidelines than the US normative ranges when used with this sample of South African high school athletes.
- Full Text:
- Authors: Mitchell, Julia
- Date: 2005
- Subjects: Brain -- Concussion , Neuropsychological tests , Sports injuries -- Psychological aspects , Head -- Wounds and injuries -- Complications
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3021 , http://hdl.handle.net/10962/d1002530 , Brain -- Concussion , Neuropsychological tests , Sports injuries -- Psychological aspects , Head -- Wounds and injuries -- Complications
- Description: Neuropsychological testing is recognised as one of the cornerstones of concussion evaluation, contributing significantly to both an understanding of the injury as well as management of the recovery process. Despite the high incidence of concussion at school level, traditional paper-and-pencil neuropsychological testing has generally been absent from school concussion management programmes, largely due to time and cost constraints. Now, the recent development of computerised neuropsychological testing is providing the opportunity for including neurocognitive assessment in this process. The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a valid and reliable instrument of this type and normed on 13 - 18 year old North American high school athletes, as well as adult groups. The current recommendation is that athletes are baselined preseason in order to provide an individualised comparative level against which to monitor recovery and provide return-to-play recommendations. This in itself is quite a cumbersome process, thus the present study set out to ascertain whether baseline testing of all athletes is necessary, or whether the use of US or SA normative data alone would provide an appropriate standard against which to interpret the postinjury scores. From a leading South African rugby playing school, the 1st and 2nd rugby teams, (16 - 18 years) were baselined using ImPACT. Three athletes, who were subsequently referred with concussion during the rugby season, were followed up with serial testing on ImPACT. An analysis of the follow up scores was conducted to chart the athletes' recovery process, in relation to the athletes own baseline scores (using US and SA reliable change indices) and age appropriate US and SA normative ranges. The relative utility of individual baselines scores versus these normative ranges was then critically evaluated. It was concluded that a combination of both baseline and normative data provided optimal management of the athlete, with the methods complementing each other in the interpretation of post-injury results. Overall, the SA normative ranges seemed to provide slightly better management guidelines than the US normative ranges when used with this sample of South African high school athletes.
- Full Text:
South Africa's growth, employment and redistribution strategy in the context of structural adjustment programmes in the South
- Authors: Lehloesa, Thembinkosi L
- Date: 2000
- Subjects: Growth, Employment And Redistribution Programme (South Africa) , South Africa -- Economic policy , South Africa -- Politics and government -- 1989-1994
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2794 , http://hdl.handle.net/10962/d1003004 , Growth, Employment And Redistribution Programme (South Africa) , South Africa -- Economic policy , South Africa -- Politics and government -- 1989-1994
- Description: This study is a contribution to the ongoing debate concerning the future of South Africa’s macro-economic policy known as the Growth, Employment and Redistribution (GEAR) strategy. The study attempts to draw parallels between the GEAR macro-economic policy framework and structural adjustment programmes in the South. By making use of this comparison, the study argues that the outcome of the GEAR will be no different from structural adjustment programmes in that it will fail to reduce poverty and cause government to meet the basic needs of the people. These conclusions are drawn from the fact that the GEAR policy is premised on the faith that the market is capable of redistributing income and wealth, and providing people with their basic needs.
- Full Text:
- Authors: Lehloesa, Thembinkosi L
- Date: 2000
- Subjects: Growth, Employment And Redistribution Programme (South Africa) , South Africa -- Economic policy , South Africa -- Politics and government -- 1989-1994
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2794 , http://hdl.handle.net/10962/d1003004 , Growth, Employment And Redistribution Programme (South Africa) , South Africa -- Economic policy , South Africa -- Politics and government -- 1989-1994
- Description: This study is a contribution to the ongoing debate concerning the future of South Africa’s macro-economic policy known as the Growth, Employment and Redistribution (GEAR) strategy. The study attempts to draw parallels between the GEAR macro-economic policy framework and structural adjustment programmes in the South. By making use of this comparison, the study argues that the outcome of the GEAR will be no different from structural adjustment programmes in that it will fail to reduce poverty and cause government to meet the basic needs of the people. These conclusions are drawn from the fact that the GEAR policy is premised on the faith that the market is capable of redistributing income and wealth, and providing people with their basic needs.
- Full Text:
Cognition and multiple sclerosis: a neuropsychological and MRI study
- Authors: Thornton, Helena Barbara
- Date: 1996
- Subjects: Multiple sclerosis -- Magnetic resonance imaging , Cognitive neuroscience
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3144 , http://hdl.handle.net/10962/d1007290 , Multiple sclerosis -- Magnetic resonance imaging , Cognitive neuroscience
- Description: Ten people with multiple sclerosis (MS) who felt they had cognitive difficulties because of their MS were investigated. This study had multiple aims. Firstly, to explore the subjective experience of cognitive deficits. Secondly, to assess whether or not there was objective evidence of cognitive difficulties on neuropsychological testing, and whether this was commensurate with a pattern of subcortical dementia. Thirdly, to determine whether their magnetic resonance imaging (MRI) scans replicated the patterns of atrophy frequently reported in MS patients with cognitive difficulties. And finally, to investigate the psychological well-being of the subjects. In depth neuropsychiatric interviews, psychiatric and psychological inventories, a comprehensive neuropsychological battery, and MRI investigations were done. The mean Full Scale Intelligence Quotient (FSIQ) fell within the superior range, at the 89th percentile. On tests of general intelligence, mental state examinations, there was little or no indication of cognitive deterioration. However, on sophisticated neuropsychological testing, there was convincing evidence of cognitive problems. Magnetic resonance imaging lesions were atypical of the reported research on cognitively compromised MS patients.
- Full Text:
- Authors: Thornton, Helena Barbara
- Date: 1996
- Subjects: Multiple sclerosis -- Magnetic resonance imaging , Cognitive neuroscience
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3144 , http://hdl.handle.net/10962/d1007290 , Multiple sclerosis -- Magnetic resonance imaging , Cognitive neuroscience
- Description: Ten people with multiple sclerosis (MS) who felt they had cognitive difficulties because of their MS were investigated. This study had multiple aims. Firstly, to explore the subjective experience of cognitive deficits. Secondly, to assess whether or not there was objective evidence of cognitive difficulties on neuropsychological testing, and whether this was commensurate with a pattern of subcortical dementia. Thirdly, to determine whether their magnetic resonance imaging (MRI) scans replicated the patterns of atrophy frequently reported in MS patients with cognitive difficulties. And finally, to investigate the psychological well-being of the subjects. In depth neuropsychiatric interviews, psychiatric and psychological inventories, a comprehensive neuropsychological battery, and MRI investigations were done. The mean Full Scale Intelligence Quotient (FSIQ) fell within the superior range, at the 89th percentile. On tests of general intelligence, mental state examinations, there was little or no indication of cognitive deterioration. However, on sophisticated neuropsychological testing, there was convincing evidence of cognitive problems. Magnetic resonance imaging lesions were atypical of the reported research on cognitively compromised MS patients.
- Full Text:
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