Positively charged styryl pyridine substituted Zn (II) Phthalocyanines for Photodynamic Therapy and Photoantimicrobial Chemotherapy
- Authors: Magadla, Aviwe , Babu, Balaji , Mack, John , Nyokong, Tebello
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190600 , vital:45009 , xlink:href="https://doi.org/10.1039/D1DT01047F"
- Description: Cationic Zn phthalocyanine complexes were synthesized using Knoevenagel reaction starting from a Zn(II) tetrakis(2-formylphenoxy)phthalocyanine (1) to form Zn(II) tetrakis(1-butyl-4-(4-(tetraphenoxy)styryl)pyridin-1-ium) phthalocyanine (2) and Zn(II) tetrakis(4-(4-(tetraphenoxy)styryl)-1-(4-(triphenylphosphonio)butyl)pyridin-1-ium)phthalocyanine (3). The photophysicochemical behaviours of the Pc complexes were assessed. The cationic complexes display high water-solubility and gave moderate singlet oxygen quantum yield in water. The cationic Pcs demonstrate good cellular uptake and photodynamic activity against MCF-7 cells with IC50 values of 8.2 and 4.9 μM for 2 and 3, respectively. The cationic Pcs also demonstrate high photoantimicrobial activity against Escherichia coli with log reductions of 5.3 and 6.0 for 2 and 3, respectively.
- Full Text:
- Date Issued: 2021
Power, Powerlessness and Radical Protest in Contemporary Cameroonian Popular Music
- Authors: Sone, Enongene Mirabeau
- Date: 2021
- Subjects: Popular music Marginal society Power (Social sciences) Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/6896 , vital:52474 , xlink:href="https://doi.org/10.1080/18125980.2021.1947154"
- Description: The fraught relationship between popular music and the various kinds of power in Africa has stimulated intensive scholarship and encouraged heated discussions on the topic. Of special interest seems to be the multifaceted character of that interrelationship. It is generally agreed that artistic expression is influenced by political power and that the two mutually inform and shape each other. This article examines the themes of power, powerlessness, and protest as they affect political governance in Cameroon, Central Africa, and as they are reflected in Cameroonian popular music. It further shows how popular songs are used to examine fundamental issues of national concern and to criticise the political leadership. The purpose of the article is to demonstrate how popular music can open a window of understanding into the current political process in Cameroon with a view to drawing implications for positive change. Written against the background of new historicism and postcolonial theories, the article is built on the assumption that popular music is a vibrant and dynamic form of oral literature which is shaped by social, economic, and political forces in present-day Cameroon. As a result, popular music has the potential to play a role in influencing a society’s perception and sense of direction. The article concludes by recommending that if the issues of power and marginality in Cameroon are to be addressed more successfully, and if the politically fraught conditions are to be ameliorated, then Cameroonians must be prepared to undergo a radical change of mentality. Keywords: Cameroon; marginalisation; popular music; power; powerlessness; radical protest
- Full Text:
- Date Issued: 2021
Preformulation characterization and identification of excipients for nevirapine loaded niosomes
- Authors: Witika, Bwalya A , Walker, Roderick B
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183126 , vital:43914 , xlink:href="https://doi.org/10.1691/ph.2021.0137"
- Description: Nevirapine (NVP) is used for the management of HIV/AIDS but must be dosed frequently, exhibits unpredictable bioavailability and a side effect profile that includes hepato- and dermo-toxicity. Niosomes are a colloidal drug delivery system that may be used to overcome the low bioavailability, side effect profile and frequent dosing needed when using conventional drug delivery systems. The compatibility of NVP with sorbitan esters, polysorbate, cholesterol and dihexadecyl phosphate (DCP) was investigated using Differential Scanning Calorimetry (DSC), Scanning Electron Microscopy (SEM), Fourier Transform Infra-red Spectroscopy (FTIR) and X-ray Powder Diffraction (XRPD). Screening studies were undertaken to identify potential excipients that would produce niosomes with target critical quality attributes (CQA) viz, a particle size (PS) less than 1000 nm, a polydispersity index (PDI) less than 0.500 and an entrapment efficiency greater than 90%. The results revealed that sorbitan esters in combination with cholesterol and 5 μmol DCP produced niosomes with the best CQA and Zeta potential (ZP) less than -30 mV which suggests good stability of the niosomes on storage. Sorbitan esters produced the smallest niosomes of less than 400 nm diameter with a PDI less than 0.400 and an entrapment efficiency of more than 78% without cholesterol. The addition of cholesterol and DCP was essential to form niosomes with target CQA.
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- Date Issued: 2021
Preliminary effectiveness of brief prolonged exposure therapy for ptsd: expanding access to effective therapies
- Authors: Booysen, Duane D , Kagee, Ashraf
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/454121 , vital:75311 , xlink:href="https://doi.org/10.1177/15346501211017989"
- Description: Over the last three decades, several empirically supported trauma therapies have been developed to treat post-traumatic stress disorder (PTSD). Yet issues such as access to treatments and dropout are ongoing barriers to adequate dissemination and implementation, especially in low resource settings. To this end, we present results on the preliminary effectiveness of a brief prolonged exposure therapy (PE) for PTSD in South Africa, a low resource setting. Based on a case-series design, seven participants (n = 7) from diverse socio-cultural backgrounds were recruited and started a six-session brief PE for PTSD and co-morbid depression and anxiety. To examine the treatment outcomes, participants were assessed at baseline, during treatment, post-intervention, and at 3-month follow-up. Overall, brief PE reduced symptoms of PTSD, depression, and anxiety from baseline to post-intervention, and at 3-month follow-up. A downward trend in symptoms was evident during treatment, with slight symptom variations during exposure sessions. In conclusion, a six-session brief PE intervention produced positive outcomes for PTSD, depression, and anxiety at two community counseling centers in South Africa. We reflect on the implementation of brief PE in a South African context.
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- Date Issued: 2021
Prevalence and clinical correlates of substance use disorders in South African Xhosa patients with schizophrenia
- Authors: Temmingh, Henk , Susser, Ezra , Mall, Sumaya , Campbell, Megan M , Sibeko, Goodman , Stein, Dan J
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/302509 , vital:58203 , xlink:href="https://doi.org/10.1007/s00127-020-01942-5"
- Description: Purpose: To determine the prevalence of substance use disorders (SUDs) in patients with schizophrenia in a sample from South Africa and compare the clinical and demographic correlates in those with and without co-occurring SUDs. Methods: Patients with schizophrenia were interviewed using the Xhosa version SCID-I for DSM-IV. We used logistic regression to determine the predictors of SUDs. Results: In the total sample of 1420 participants, SUDs occurred in 47.8%, with the most prevalent SUD being cannabis use disorders (39.6%), followed by alcohol (20.5%), methaqualone (6.2%), methamphetamine (4.8%) and other SUDs (cocaine, ecstasy, opioids, 0.6%). Polydrug use occurred in 40%, abuse occurred in 13.5%, and 39.6% had at least one substance dependence diagnosis. Signifcant predictors of any SUD were younger age (41–55 vs. 21–30: OR=0.7, 95% CI=0.5–0.9), male sex (OR=8.6, 95% CI=5.1–14.6), inpatient status (OR=1.7, 95% CI=1.3–2.1), post-traumatic stress symptoms (OR=4.6, 95% CI=1.6–13.3), legal (OR=3.4, 95% CI=2.0–5.5) and economic problems (OR=1.4, 95% CI=1.0–2.0). Methamphetamine use disorders occurred signifcantly less often in the Eastern compared to the Western Cape provinces. Inpatient status and higher levels of prior admissions were signifcantly associated with cannabis and methamphetamine use disorders. Post-traumatic stress symptoms were signifcantly associated with alcohol use disorders. Anxiety disorders were associated with other SUDs. Conclusion: SUDs occurred in almost half of the sample. It is important for clinicians to identify the presence of SUDs as their presence is associated with characteristics, such as male sex, younger age, inpatient status, more prior hospitalisations, legal and economic problems, PTSD symptoms and anxiety.
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- Date Issued: 2021
Prevalence and determinants of tobacco use amongst South African adults with mental illness in the Eastern Cape
- Authors: Tindimwebwa, Linda K , Ajayi, Anthony I , Adeniyi, Oladele Vincent
- Date: 2021
- Subjects: mental health mental illiness tobacco use Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7278 , vital:53109 , xlink:href="https://doi.org/10.4102/sajpsychiatry.v27i0.1637"
- Description: Background: Given the physical and mental health consequences of tobacco use amongst individuals with mental illness, it was imperative to assess the burden of tobacco use in this population. Aim: This study examined the patterns and factors associated with tobacco use in individuals attending the outpatient unit. Setting: Cecilia Makiwane Hospital Mental Health Department in Eastern Cape province, South Africa. Methods: Lifetime (ever use) use and current use of any tobacco products were examined in a cross-sectional study of 390 individuals between March and June 2020. A logistic regression was fitted to determine the correlates of lifetime and current use of any tobacco products. Results: The rates of ever use and current use of tobacco products were 59.4% and 44.6%, respectively. Of the participants interviewed, lifetime tobacco use was more prevalent amongst individuals with schizophrenia (67.9%) and cannabis-induced disorders (97.3%) and lower in those with major depressive disorders (36.1%) and bipolar and related disorders (43.5%). Men were six times more likely to have ever used or currently use tobacco products in comparison to women. Also, those who had a salaried job or owned a business were over three times more likely to have ever used or currently use tobacco products compared with those receiving government social grants. Conclusions: The prevalence of tobacco use in this study was significantly higher than the general population in the Eastern Cape. Therefore, smoking prevention and cessation interventions targeted at the general population should target this often neglected sub-population in the region. Keywords: Eastern Cape province; mental health users; mental illness; South Africa; tobacco use.
- Full Text:
- Date Issued: 2021
Prevalence and factors associated with suicidal ideation amongst college students in the Nelson Mandela Bay Municipality, South Africa
- Authors: Alabi, Adeyinka A , Oladimeji, Olawumi K , Adeniyi, Oladele Vincent
- Date: 2021
- Subjects: Suicidal behaviour Education (Higher) Students Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7235 , vital:53093 , xlink:href="https://doi.org/10.4102/safp.v63i1.5195"
- Description: Background: Suicidal behaviour amongst college students constitutes a significant social and public health problem globally. This study determined the prevalence and associated factors of suicidal ideation amongst students of higher education in the Nelson Mandela Bay Municipality (NMBM), South Africa. Methods: In this institution-based cross-sectional study, a multistage cluster sampling of 826 participants, drawn from a college in NMBM, was conducted from January to March 2020. Data were collected with a standardised self-administered questionnaire. Multivariable logistic regression analysis was used to identify the factors associated with suicidal ideation. Results: Participants’ ages ranged from 18 to 24 years, with a mean age of 20.49 years (standard deviation, 1.88 years). The lifetime prevalence of suicidal ideation and plans in the preceding 12 months were 24.5% and 9.6%, respectively. The odds of suicidal ideation were higher in students who experienced bullying (adjusted odds ratio [AOR], 1.89; 95% confidence interval [CI], 1.35–2.65), mental illness (AOR, 1.89; 95% CI, 1.35–2.65), a history of sexual assault (AOR, 2.50; 95% CI, 1.20–5.21) and experience of sexual assault by or to a close family member (AOR, 1.69; 95% CI, 1.01–2.82). Underlying chronic illness was associated with a twofold risk for suicidal ideation in both sexes. Conclusion: About a quarter of the students sampled at the college had experienced suicidal ideation and some had had suicidal plans in the preceding 12 months. Screening for the identified risk factors amongst the student population coupled with prompt interventions would mitigate the risk of suicide in the study population. Keywords: suicidal behaviour; suicidal plans; higher education; students; South Africa.
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- Date Issued: 2021
Prevalence and Implications of Telecommunication Counselling
- Authors: Lusiba, Sinazo.
- Date: 2021
- Subjects: Counseling
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7554 , vital:54349
- Description: ABSTRACT The purpose of the present study was to explore prevalence and implications of telecommunication counselling. Available literature suggests that telecommunication counselling may have far-reaching implications in the mental health practice in general, and particularly in psychology. This study was guided by the social information processing theoretical framework. A total number of 26 mental health practitioners aged from 22 to 45 were selected using purposive sampling. In this study questionnaires were distributed to respondents through email, email was also used to collect the research data. Research ethics, such as confidentiality, anonymity, and voluntary participation, were strictly observed. The Statistical Package for Social Sciences version 23 was used to analyse the data. The analysed data are presented in frequency tables and graphs. This study found that there are effectiveness and efficiency factors associated with the use telecommunication counselling. Furthermore, the findings imply that the popularity of this type of counselling has been growing steadily in the past few years, especially in urban areas. Furthermore, despite the increase and growing popularity in the use of telecommunication counselling, the results suggest the presence of ethical dilemmas that confront the practitioners. , Thesis (Masters) -- Faculy of Humanities, Social Sciences and Law, 2021
- Full Text:
- Date Issued: 2021
Primary healthcare approach to substance abuse management
- Authors: Kaswa, Ramprakash
- Date: 2021
- Subjects: Substance abuse Diseases Primary health care Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7259 , vital:53104 , xlink:href="https://doi.org/10.4102/safp.v63i1.5307"
- Description: Substance abuse is common amongst patients attending primary healthcare settings. Despite the substantial impact on one’s health, substance abuse is often underdiagnosed by primary care providers owing to a lack of training and time for screening. Self-reported screening tools are easy to administer and efficient to make a substance abuse diagnosis in primary care settings. Comorbid mental illness and intimate partner violence are common amongst patients presenting with substance abuse in primary care. An early diagnosis and a brief behavioural change counselling are effective in managing substance abuse before it develops into dependency. A brief motivational communication rather than a confrontation during substance abuse screening, counselling and treatment is important to achieve optimum patient outcomes. Keywords: substance abuse; primary healthcare setting; screening tools; brief behavioural change counselling; co-morbidity
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- Date Issued: 2021
Prioritisation of targets for weed biological control I: a review of existing prioritisation schemes and development of a system for South Africa
- Authors: Downey, Paul O , Paterson, Iain D , Canavan, Kim N , Hill, Martin P
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/417763 , vital:71484 , xlink:href="https://doi.org/10.1080/09583157.2021.1918636"
- Description: Biological control is widely utilised for the management of invasive alien plants (IAP). With the ever-increasing number of IAPs, it is important to prioritise targets for biocontrol in order to maximise the use of resources and the chances of success. This paper reviewed 12 previous systems developed to prioritise plant targets for biocontrol. The review underpins the selection of attributes and methodologies for the prioritisation of targets for biocontrol in South Africa. All of the previous systems are purpose-built and context-specific, so a new system is required for the South African setting. Previous prioritisation systems were assessed based on the attributes and methodology adopted. The attributes of previous systems were grouped into three sections, being (1) impact/importance of the target plant, (2) likelihood of achieving success, and (3) investment required. Nineteen attributes from previous systems are included in the new system, while nine were excluded due to a requirement for legislation and/or research, or because they conflicted with objectives of the new system in some way. Two methodological approaches were identified for how systems sourced information, either sourcing information through expert knowledge or the use of available literature and data. This information was then applied through either a quantitative or qualitative scoring method. A quantitative scoring method, with information sourced from available resources, was selected as the most appropriate methodology in the context of the new system for South Africa. This review streamlined the development and testing of the South African Biological Control Target Selection system.
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- Date Issued: 2021
Progress and prospects for the biological control of invasive alien grasses Poaceae) in South Africa
- Authors: Sutton, Guy F , Bownes, Angela , Visser, Vernon , Mapaura, Anthony , Canavan, Kim N
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/414448 , vital:71147 , xlink:href="https://hdl.handle.net/10520/ejc-ento_v29_n3_a12"
- Description: Historically, invasive alien grasses have not been considered a major threat in South Africa, and as a result, very few resources are allocated to their management. However, there is an increasing awareness of the severe environmental and socio-economic impacts of invasive grasses and the need for appropriate management options for their control. South Africa has a long history of successfully implementing weed biological control (biocontrol) to manage invasive alien plants, however much like the rest of the world, invasive grasses do not feature prominently as targets for biocontrol. The implementation and early indicators of success of the few grass biocontrol programmes globally and the finding that grasses can be suitable targets, suggests that biocontrol could start to play an important role in managing invasive alien grasses in South Africa. In this paper, we evaluated the prospects for implementing novel grass biocontrol projects over the next ten years against 48 grasses that have been determined to represent the highest risk based on their current environmental and economic impacts. The grasses were ranked in order of priority using the Biological Control Target Selection system. Five grasses were prioritised – Arundo donax L., Cortaderia jubata (Lem.) Stapf, Cortaderia selloana (Schult and Schult) Asch. and Graebn., Nassella trichotoma (Hack. ex Arech.), and Glyceria maxima (Hartm.) Holmb., based on attributes that make them suitable biocontrol targets. Arundo donax has already been the target of a biocontrol programme in South Africa. We reviewed the progress made towards the biocontrol of this species and discuss how this programme could be developed going forward. Moreover, we outline how biocontrol could be implemented to manage the remaining four high-priority targets. While biocontrol of grasses is not without its challenges (e.g. unresolved taxonomies, conflicts of interest and a lack of supporting legislation), South Africa has an opportunity to learn from existing global research and begin to invest in biocontrol of high-priority species that are in most need of control.
- Full Text:
- Date Issued: 2021
Promising photodynamic antimicrobial activity of polyimine substituted zinc phthalocyanine and its polycationic derivative when conjugated to nitrogen, sulfur, co-doped graphene quantum dots against Staphylococcus aureus
- Authors: Sen, Pinar , Nyokong, Tebello
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/185304 , vital:44363 , xlink:href="https://doi.org/10.1016/j.pdpdt.2021.102300"
- Description: Antimicrobial resistance is a most important problem facing the treatment of infectious diseases. Antimicrobial photodynamic therapy is an alternative treatment strategy, considered to be cost-effective and feasible. For this purpose, octa-imine substituted ZnPc (3) have been prepared and conjugated to nitrogen, sulfur co-doped graphene quantum dots (N,S-GQDs) through π-π stacking. The photophysical and photochemical properties of Pc alone and and Pc-conjugated to the GQD nanomaterial such as absorption, fluorescence, fluorescence life time, singlet oxygen quantum yields, triplet state quantum yields and exited state lifetimes were investigated in solutions before in vitro cell studies. The PACT activity of prepared structures was investigated against Gram-positive (Staphylococcus aureus). Our results suggest that the in the case of conjugation of zinc Pc to N,S-GQDs, photodynamic inactivation increased with the 100 % reduction percentage.
- Full Text:
- Date Issued: 2021
Prospects for the biological control of Northern Temperate Weeds in South Africa
- Authors: Martin, Grant D
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/414478 , vital:71151 , xlink:href="https://hdl.handle.net/10520/ejc-ento_v29_n3_a10"
- Description: The Northern Temperate Weeds programme is a novel biological control (biocontrol) programme started in 2017, with the aim of reducing the impacts of northern temperate weeds that are common, widespread and problematic in the high elevation grasslands of South Africa. As these regions are the most important systems for water security, providing nearly 50% of all water run-off, it is surprising that these species were not targeted for biocontrol previously. Thus far, research has focused on biocontrol feasibility as well as ecological and socio-economic impact studies on several northern temperate weeds, including Pyracantha angustifolia (Franch.) C.K.Schneid, Rosa rubiginosa L., Cotoneaster spp., Rubus spp., (all Rosaceae) and Salix spp. (Salicaceae). In addition, research conducted in the USA and Europe on the natural enemies associated with two of these species, Robinia pseudoacacia L. and Gleditsia triacanthos L. (both Fabaceae and native to the USA), have provided South African researchers with the necessary foundation to initiate programmes against these weeds. Research in South Africa is currently focused on pre-release studies on R. pseudoacacia, using the leaf miner Odontota dorsalis Thunberg (Coleoptera: Chrysomelidae) and the black locust midge Obolodiplosis robiniae Haldeman (Diptera: Cecidomyiidae), and on G. triacanthos, using a seed bruchid, Amblycerus robiniae F. (Coleoptera: Chrysomelidae). Progress with these programmes and potential constraints that may limit success, are discussed.
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- Date Issued: 2021
Push-pull type Co (III) corroles
- Authors: Niu, Yingjie , Zhu, Weihua , Mack, John , Dubazana, Nadine , Nyokong, Tebello , Fu, Bo , Xu, Haijun , Liang, Xu
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190826 , vital:45032 , xlink:href="https://doi.org/10.1142/S1088424621500279"
- Description: The rational design and preparation of three A2B type Co(III)triarylcorroles with push- and pull-substituents are reported. The structure-property relationships were identified by comparing their optically spectroscopic and electrochemical properties to trends predicted in DFT and TD-DFT calculations. The results demonstrate that the Co(III)triarylcorroles are highly efficient catalysts for electrocatalyzed hydrogen evolutions (HERs) and oxygen reductions (ORRs), and that their reactivity can be modulated by changing the meso-B-substituent of the Co(III)Corroles.
- Full Text:
- Date Issued: 2021
Rapid Synthesis of Thiol-Co-Capped-CdTe/CdSe/ZnSe Core Shell-Shell Nanoparticles
- Authors: Daramola, Olamide , Siwe-Noundou, Xavier , Tseki, Potlaki , Krause, Rui W M
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/191758 , vital:45161 , xlink:href="https://doi.org/10.3390/nano11051193"
- Description: CdTe QDs has been demonstrated in many studies to possess good outstanding optical and photo-physical properties. However, it has been established from literature that the toxic Cd2+ that tends to leak out into nearby solutions can be protected by less toxic ZnS or ZnSe shells leading to the synthesis of core-shells and multi-core-shells. Hence, this has allowed the synthesis of CdTe multi-core-shells to have gained much interest. The preparation of most CdTe multi-core-shells reported from various studies usually has a longer reaction time (6–24 h) in reaching their highest emission maxima. The synthesis of CdTe multi-core-shells in this study only took 35 min to obtain a highest emission maximum compared to what has been reported from the literature. CdTe multi-core-shells were synthesized by injecting 7, 14, and 21 mL each of Zn complex solution and Se ions into the reacting mixture containing CdTe core-shells (3 h) at 5 min intervals over a 35 min reaction time. The emission maxima of the MPA-TGA-CdTe multi-core-shells at 21 mL injection was recorded around 625 nm. Therefore, we are reporting the rapid synthesis of five different thiol co-capped CdTe/CdSe/ZnSe multi-core-shell QDs with the highest emission maxima obtained at 35 min reaction time.
- Full Text:
- Date Issued: 2021
Re-engineering imperatives to enhance the effectiveness of municipal public accounts committees in South African municipalities
- Authors: Mofolo, Malefetsane A. , Adonis, Vuyo
- Date: 2021
- Subjects: Criminal liability Maleficence Municipal finance--Accounting Reengineering (Management) Article
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/7179 , vital:53082 , xlink:href="https://doi.org/10.4102/apsdpr.v9i1.510"
- Description: Background: After 26 years into democracy and 20 years of the new local government operations, the state of the majority of municipalities in South Africa still leaves much to be desired, as they are plagued with maleficence. What is concerning is that these negative tendencies that are troubling local government occur even under the watchful eye of the municipal public accounts committees (MPACs). Aim: The aim of this study was to evaluate the composition and the role of MPACs, which have experienced a number of challenges since they were introduced in response to the widely held perception of the culture of lack of accountability in South African municipalities. Methods: This article is theoretical in nature, and it draws its arguments from secondary data in order to understand the composition and the role of MPACs, including its challenges. Results: This study regards the composition of the MPAC as lacking the necessary vigour to be efficient and effective in executing its duties, particularly when considering the challenges and political influences that it tends to face in its operations. Conclusion: The study concludes that there is a need for re-engineering of the composition and the role of the MPAC in order to ensure that it executes its functions efficiently and effectively. Consequently, the study recommends three cardinal pillars that must be given attention in re-engineering the MPAC: policy, authority and power. Keywords: Internal accountability; maleficence; municipalities; municipal public accounts committees; re-engineering
- Full Text:
- Date Issued: 2021
Re-thinking freedom: selected Life-Writings of South African Born-frees
- Authors: Mpendulo, Mashumi
- Date: 2021
- Subjects: Born-Frees , Freedom of expression , Post-apartheid era -- South Africa
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3400 , vital:43339
- Description: Ideas of freedom in post-apartheid South Africa cannot be understood in isolation from the lived experiences of the people we often consider as the future of South Africa. Freedom is a time-bound value whose meaning keeps changing as time goes by, and our understanding of freedom before 1994 cannot be the same as today. With close reference to the selected life writings of South African born-frees, this study examines ideas of freedom as expressed in these texts written from the perspectives of ordinary young black people in post-apartheid South Africa. It unpacks the youth’s rejection of the tag ‘born-free’ by bringing out the difficulties of their upbringing in poverty and inequality. This work argues that poverty, inequality, unemployment, and dilapidated infrastructure in public schools are still very much a feature of post-apartheid South Africa, and that the government is yet to fully transform the lives of ordinary black people who much as they try to do so themselves, are still faced with structural inequalities, physical and symbolic violence. Through decolonial theory, the selected texts are analysed to trace the legacies of colonialism and apartheid and how notions of freedom have changed over time. , Thesis (MA) -- Faculty of Humanities, Social Sciences and Law, 2021
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- Date Issued: 2021
Reshaping our musical values: decolonising teaching and curricular frameworks in the Eastern Cape
- Authors: McConnachie, Boudina E
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/480216 , vital:78407 , xlink:href="https://doi.org/10.1080/17411912.2021.1930090"
- Description: Musical ideals set by European standards and values, entrenched through colonial oppression and promoted by the continued veneration of Western culture need to be re-evaluated. This short essay in an alternative format of a critical report records the development and implementation of an African instrumental music studies course at Rhodes University, introduced to re-value and promote African ways of making and interacting with music. As a result of in-depth research with regard to the ailing Indigenous African Music (IAM) syllabus in the South African national school music curriculum, this university-level course has been designed to generate future teachers and culture-bearers who will possess a deeper understanding of, and feeling for, Indigenous African musics and who, as a result, will be able to engage with African musics through teaching and learning. Highlighting the crisis in South African music education decolonisation, this paper will also present other proposed solutions to this problem.
- Full Text:
- Date Issued: 2021
Rethinking the decolonial moment through collaborative practices at the International Library of African Music (ILAM), South Africa
- Authors: Watkins, Lee W , Madiba, Elijah M , McConnachie, Boudina E
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/480227 , vital:78409 , xlink:href="https://doi.org/10.1080/17411912.2021.1938628"
- Description: Until recently the International Library of African Music (ILAM) was at the receiving end of widespread criticisms because most of its collections were acquired through the colonial privilege of its founder, Hugh Tracey. Tracey recorded music and collected musical instruments in many countries of sub-Sahara Africa without following the rigorous ethical practices which are a necessary requirement for collectors these days. Since its establishment in 1954 until the early 2000s, moreover, ILAM had largely been inaccessible to black South Africans who comprise the majority of the population. Its presence, therefore, is complicated by a racist past associated with apartheid and a colonial past characterised by the misappropriation of the colonised's resources. In view of this history, ILAM had to shape a new reality which fell in line with calls and demands for decolonised practices such that the archive became an agent for transformation on numerous fronts. This series of articles describes the efforts undertaken by ILAM so that it could develop and implement policies which would place it at the vanguard of ethical archival practices on the continent. It is argued that the decolonial could be realised only through collaboration with entities which shared our interests in participatory and transformed archival practices.
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- Date Issued: 2021
Review of the Traditional Uses, Phytochemistry, and Pharmacological Activities of Rhoicissus Species (Vitaceae)
- Authors: Dube, Nondumiso , Siwe-Noundou, Xavier , Krause, Rui W M , Kemboi, Douglas , Tembu, Vuyelwa J , Manicum, Amanda-Lee
- Date: 2021
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/191769 , vital:45162 , xlink:href="https://doi.org/10.3390/molecules26082306"
- Description: Species within the genus Rhoicissus (Vitaceae) are commonly used in South African traditional medicine. The current review discusses the occurrence, distribution, traditional uses, phytochemistry, and pharmacological properties of Rhoicissus species covering the period 1981–2020. The data reported were systematically collected, read, and analysed from scientific electronic databases including Scopus, Scifinder, Pubmed, and Google Scholar. Reported evidence indicates that species in this genus are used for the treatment of gastrointestinal complaints, sexually transmitted infections (STIs), and infertility, as well as to tone the uterus during pregnancy and to facilitate delivery. Pharmacological studies have further shown that members of the Rhoicissus genus display antidiabetic, uterotonic, ascaricidal, hepatoprotective, antioxidant, antimicrobial, anticancer, and anti-inflammatory properties. They are linked to the presence of bioactive compounds isolated from the genus. Hence, Rhoicissus species can potentially be an alternative therapeutic strategy to treat diseases and develop safer and more potent drugs to combat diseases. Plant species of this genus have valuable medicinal benefits due to their significant pharmacological potential. However, scientific investigation and information of the therapeutic potential of Rhoicissus remain limited as most of the species in the genus have not been fully exploited. Therefore, there is a need for further investigations to exploit the therapeutic potential of the genus Rhoicissus. Future studies should evaluate the phytochemical, pharmacological, and toxicological activities, as well as the mode of action, of Rhoicissus crude extracts and secondary compounds isolated from the species.
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- Date Issued: 2021