Evaluation of rate of swelling and erosion of verapamil (VRP) sustained-release matrix tablets
- Authors: Khamanga, Sandile M , Walker, Roderick B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184232 , vital:44192 , xlink:href="https://doi.org/10.1080/03639040600599822"
- Description: Tablets manufactured in-house were compared to a marketed sustained-release product of verapamil to investigate the rate of hydration, erosion, and drug-release mechanism by measuring the wet and subsequent dry weights of the products. Swelling and erosion rates depended on the polymer and granulating fluid used, which ultimately pointed to their permeability characteristics. Erosion rate of the marketed product was highest, which suggests that the gel layer that formed around these tablets was weak as opposed to the robust and resistant layers of test products. Anomalous and near zero-order transport mechanisms were dominant in tests and commercial product, respectively.
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- Date Issued: 2006
Household fuelwood use in small electrified towns of the Makana District, Eastern Cape, South Africa
- Authors: Shackleton, Charlie M , Gambiza, James , Jones, R
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182362 , vital:43823 , xlink:href="https://doi.org/10.17159/2413-3051/2007/v18i4a3394"
- Description: Access to secure energy supplies is a key foundation for sustainable development. Consequently local planning and development initiatives must be based on a sound knowledge of the energy use patterns and preferences of local users. This paper reports on such for three small urban settlements in the Eastern Cape Province, with a particular focus on fuelwood use. Despite widespread electrification over a decade ago, and perceptions that the ease of fuelwood collection was declining, most households continued to use fuelwood for cooking and space heating, whereas electricity was favoured for lighting. The most common reason for this was because fuelwood was cheap (or free) compared to electricity. Annual demand was approximately 1 450 kg per household per year. Households that collected their own supplies of fuelwood were significantly poorer than those that either bought their stocks, or those that did not use fuelwood at all. Indigenous species were favoured over exotic species, although fuelwood vendors traded mostly in exotic species, particularly Eucalyptus and wattle. The greater reliance of poorer and unelectrified households on fuelwood requires that local authorities consider this in energy planning, otherwise the poor will be neglected in policies such as the Free Basic Electricity.
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- Date Issued: 2006
Household wealth status and natural resource use in the Kat River valley, South Africa
- Authors: Shackleton, Charlie M , Shackleton, Sheona E
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/181301 , vital:43717 , xlink:href="https://doi.org/10.1016/j.ecolecon.2005.04.011"
- Description: Much work has demonstrated the significant role and value of non-timber forest products (NTFPs) in the livelihoods of rural people in southern Africa and elsewhere. The findings provide a mean or composite picture, averaged across the sample households within each community. Yet, within any given community, there is significant socio-economic differentiation. It is important to acknowledge such differentiation when considering policy and management interventions to support rural livelihoods and promote sustainable resource use. This paper reports on a study in South Africa, the objective of which was to explore wealth-related differences and similarities in the use and value of NTFPs. Data on NTFP consumption, purchase, and sale were collected from households in three rural villages. Households were divided into three wealth classes and patterns of NTFPs use between the classes examined. There was no difference in the proportions of households in each wealth class using NTFPs, nor the total number of NTFPs used per household. Yet, there was some supporting evidence that poorer households derive greater benefits from NTFPs than do wealthy or intermediate households. One clear difference was that, with increasing wealth, households purchased significantly more NTFPs, and a greater proportion of wealthy households did so. Conversely, a greater proportion of poor households were involved in the sale of one or more NTFPs, and they sold a greater number per household, compared to wealthy and intermediate households. Detailed examination of use and value of four NTFPs (fuelwood, wild fruits, edible herbs, and grass hand brushes) revealed that in all instances, the poorest households used more of the resource per capita than the other wealth classes. This was not the case for comparisons based on the total household as the unit of analysis. Gross annual direct-use value did not differ between the wealth classes for any of the four NTFPs examined, at the household level. But on a per capita basis, a significantly higher gross annual direct-use value was evident within poorer households for fuelwood and edible herbs. The significance of these differences is discussed.
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- Date Issued: 2006
Identifying needs and opportunities for local government environmental education and training in South Africa
- Authors: Olvitt, Lausanne L , Hamaamba, Tyson
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/370991 , vital:66400 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122739"
- Description: Effective environmental management and public engagement with environmental concerns are needed for the attainment of sustainable development goals and socio-ecological balance in local government contexts. This vision is clearly articulated in international environmental policy frameworks and in South Africa’s national and regional legislation. However, policy and legislation fall short of identifying the range of a priori competences required by local government officials and environmental managers before well intended policy can be translated into effective practice. This paper reports on recent research into identifying the underlying competences required for better environmental management and the establishment of education and training processes for local government managers. The research draws on the notion of ‘applied competence’ put forward by South Africa’s National Qualifications Framework, and argues that greater attention needs to be paid to competence-based capacity building processes within local government departments if environmental sustainability and development goals are to be met. The paper draws on the researchers’ experiences of formulating a national level generic competence framework for environmental management, and conducting an education and training needs analysis for the Makana Municipality in the Eastern Cape province of South Africa. Early findings suggest that a broad range of competences all have a role in ensuring the capacity and effectiveness of local governments to better manage their local environment. The paper argues that these are significant for the development of environmental education and training programmes in local government contexts.
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- Date Issued: 2006
Incorporating fishermen’s local knowledge and behavior into geographical information systems (GIS) for designing marine protected areas in Oceania
- Authors: Shankar, Aswani , Lauer, Matthew
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/439109 , vital:73545 , xlink:href="https://doi.org/10.17730/humo.65.1.4y2q0vhe4l30n0uj"
- Description: Drawing on our experience in establishing marine protected areas (MPAs) in the Roviana and Vonavona Lagoons, New Georgia, Solomon Islands, this paper shows how a geographical information system (GIS) database can be used to incorporate sociospatial information, such as indigenous knowledge and artisanal fishing data, along with biophysical and other information to assist in MPA design. We argue that converting peoples’ knowledge and socioecological behavior into geo-spatial data allows researchers to formulate hypotheses regarding human responses to inter- and intra-habitat variability, along with other marine ecological processes, and help in the designing and implementation of resource management strategies in a cost-effective and participatory way, bridging the gap between indigenous and Western cognitions of seascapes. More generally, we show the significance of combining spatial tools, anthropological fieldwork, and social and natural science methods for studying artisanal fisheries with the goal of aiding the design of marine protected areas.
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- Date Issued: 2006
Joking around in Zimbabwe, undoing and redoing participation
- Authors: Price, Leigh
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373715 , vital:66716 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122750"
- Description: In Zimbabwe, I teach a participatory course on environmental education to trainers. The course is an adaptation of a course designed by Rhodes University, South Africa. It gives participants a background in educational theories and has a strong theoretical component built around a focus on practice. During the time that the course was being delivered to non-industry participants, the theoretical component of the course was whole-heartedly embraced. We assumed that calling the course ‘participatory’ presupposed the need for this theory because within the theory were the tools for emancipation. And participation, we believed, had an emancipatory mandate. However, when we decided to redevelop the course for industry, we were uncomfortably surprised by the request from a majority of industry participants to reduce the theory and concentrate solely on skills-based training. This paper documents how this discomfort resulted in my adjusting my view of participation.
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- Date Issued: 2006
Learning about participation in integrated water resources management: A South African review
- Authors: Burt, Jane C , du Toit, Derick , Neves, David , Pollard, Sharon
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/433025 , vital:72924 , xlink:href="https://wrcwebsite.azurewebsites.net/wp-content/uploads/mdocs/TT293-06.pdf"
- Description: The National Water Act (1998) opens the way for ordinary people to take part in water resource management (WRM). This is a significant move towards a more social orientation and away from an approach that focused almost exclusively on the technical aspects of WRM. This set of two books asks what a social orientation means in practice. Since the National Water Act became law in 1998, how have WRM practitioners involved people in the process of managing water? What have we learnt so far? And how can we use these lessons to move forward? The content of the books is based on research that looked in some depth at national and local participatory practice in South Africa, and also broadly at international trends. The research was conducted by three WRM practitioners and two researchers in the field of participatory approaches.
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- Date Issued: 2006
Negotiating impoverishment: Farm worker responses to displacement following land invasions in Zimbabwe's "Fast Track Land Reform Programme"
- Authors: Hartnack, Andrew Michael Carl
- Date: 2006
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/197076 , vital:45834
- Description: This thesis investigates the impacts of sudden, unplanned, and violent displacement on farm workers such as Frank Juwawo during Zimbabwe’s recent Fast Track Land Reform Programme. It seeks to illustrate how the members of a complex community were differentially impacted by displacement and displayed differing abilities to mitigate the resulting social and economic impoverishment. In order to illuminate this particular displacement scenario, this thesis uses theoretical and analytical tools developed in the field of displacement studies, adapting them to suit the kind of displacement experienced by Zimbabwean farm workers. , Thesis (MA) -- Faculty of Humanities, Anthropology, 2006
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- Date Issued: 2006
Promoting sustainable development through whole school approaches: an international, intercultural teacher education research and development project
- Authors: Shallcross, Tony , Loubser, Callie , Le Roux, Cheryl , O'Donoghue, Rob B , Lupele, Justin
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/433066 , vital:72929 , xlink:href="https://doi.org/10.1080/02607470600782427"
- Description: This paper focuses on a British Council funded Higher Education Link project involving three institutions—Manchester Metropolitan University (MMU) in the UK and two South African institutions, the University of South Africa (UNISA) and Rhodes University. The link is a research and development project that has three main research strands: contextual profiling that will establish the applicability of a European teacher education project to the South African context, evaluative materials development and piloting predicated on a respect for indigenous and contextual knowledge, and impact analysis that will examine the role of multidirectional intergenerational mentoring in disseminating messages about sustainable lifestyles. The project is strongly influenced by the South African Revised National Curriculum statements pertaining to environment and an analysis of the impact that these materials have had on promoting whole school approaches to environmental education in South Africa. The link's initial purpose is to develop advanced certificate in education (ACE) course materials that will promote whole school approaches to environmental education, based on developing concepts of collaboration, pupil participation, educational process and action in schools in South Africa. Materials from the MMU‐based, European Commission funded Sustainability Education in European Primary Schools (SEEPS) Project will be adapted for use in South Africa by UNISA and Rhodes.
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- Date Issued: 2006
Self-assembled monolayers (SAMs) of cobalt tetracarboxylic acidchloride phthalocyanine covalently attached onto a preformed mercaptoethanol SAM
- Authors: Mashazi, Philani N , Ozoemena, Kenneth I , Maree, David M , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/283792 , vital:55989 , xlink:href="https://doi.org/10.1016/j.electacta.2005.10.004"
- Description: A feasible method of fabricating phthalocyanine sensor was developed by covalent attachment of cobalt tetracarboxylic acidchloride phthalocyanine (CoTCACIPc) onto a preformed 2-mercaptoethanol (2-ME) self-assembled monolayer (SAM) modified gold electrode (designated as CoTCACIPc-2-ME-SAM). The surface concentration of the CoTCACIPc was found to be 4.58 × 10−10 mol/cm2. The sensor gave a linear response to L-cysteine over the concentration range 0.28–20 μM with a detection limit of 5 × 10−7 M and best response time of 2 s.
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- Date Issued: 2006
Self-assembled monolayers and electropolymerized thin films of phthalocyanines as molecular materials for electroanalysis
- Authors: Nyokong, Tebello , Bedioui, Fethi
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/283826 , vital:55994 , xlink:href="https://doi.org/10.1142/S1088424606000454"
- Description: In this review, we report on the newly developed area of research devoted to the formation of self-assembled monolayers of metallophthalocyanines by focusing on some significant examples dedicated to electroanalytical applications. We also summarize recent examples on the use of electropolymerized metallophthalocyanine films in electroanalysis. In both cases, activation and detection of thiols are the main targeted applications.
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- Date Issued: 2006
Self-assembled monolayers and electropolymerized thin films of phthalocyanines as molecular materials for electroanalysis
- Authors: Nyokong, Tebello , Bedioui, Fethi
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/283851 , vital:55996 , xlink:href="https://doi.org/10.1142/S1088424606000454"
- Description: In this review, we report on the newly developed area of research devoted to the formation of self-assembled monolayers of metallophthalocyanines by focusing on some significant examples dedicated to electroanalytical applications. We also summarize recent examples on the use of electropolymerized metallophthalocyanine films in electroanalysis. In both cases, activation and detection of thiols are the main targeted applications.
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- Date Issued: 2006
Situated environmental learning in Southern Africa at the start of the UN decade of education for sustainable development
- Authors: O'Donoghue, Rob B , Lotz-Sisitka, Heila
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183059 , vital:43908 , xlink:href="https://doi.org/10.1017/S0814062600001737"
- Description: Within the globalising trajectory of modernism, conservation, then environmental (EE) and now sustainability education (ESD) have each emerged as developing responses to risk produced by and in the modern state. Through adopting a long term process perspective, this paper narrates the emergence of situated learning perspectives and a developing re-orientation of EE at the start of the United Nations Decade of Education for Sustainable Development (UNDESD). We identified the need to examine ESD practice in responses to recent ESD consultations in 14 southern African countries, where a rhetorical marking was noted in discussions on ESD practices, particularly with regard to changing teaching and learning processes. The paper narrates how an interplay of review, research and practical engagement activities have all contributed to an extended critical review of learning interactions in environmental education in an attempt to provide useful perspective for educational activities within the UNDESD. We found that EE and ESD initiatives only acquired more substantive meaning and coherent orientation when examined within ongoing inquiries into situated learning, agency and risk reduction in contexts of poverty, vulnerability and risk, the key concern to us in this paper and the primary focus of the WEHAB (Water, Energy, Health, Agriculture and Biodiversity) sustainable development agenda in the region.
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- Date Issued: 2006
Spotlight on research: 50 years of Pharmaceutical Sciences Research Excellence Faculty of Pharmacy Rhodes University
- Authors: Walker, Roderick B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184243 , vital:44193 , xlink:href="https://hdl.handle.net/10520/EJC81478"
- Description: This year, the Faculty of Pharmacy at Rhodes University is celebrating its 50th Anniversary. Over 2000 BPharm, 33 BSc honours, 65 MSc and 27 PhD degrees have been conferred since the Faculty’s inception. The diverse research activities and dedicated academic staff have ensured that the Faculty of Pharmacy has high visibility with respect to research outputs, as is evidenced by the appointment of various members of staff to national and international research, regulatory and professional committees, as well as to serving on the editorial boards of a number of international journals. In addition, staff regularly publish in international and local peer-reviewed journals and present their research findings at international and local conferences.
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- Date Issued: 2006
Synthesis and electrochemical characterisation of α-and β-tetra-substituted oxo (phthalocyaninato) titanium (IV) complexes
- Authors: Tau, Prudence , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/283869 , vital:55998 , xlink:href="https://doi.org/10.1016/j.poly.2005.11.025"
- Description: The synthesis, spectroscopic and electrochemical characterisation of the following oxotitanium tetra-substituted phthalocyanines are reported: 1,(4)-(tetraphenoxyphthalocyaninato)titanium(IV) oxide (5a); 1,(4)-(tetra-tert-butylphenoxyphthalocyaninato)titanium(IV) oxide (5b); 2,(3)-(tetraphenoxyphthalocyaninato)titanium(IV) oxide (6a) and 2,(3)-(tetra-tert-butylphenoxyphthalocyaninato)titanium(IV) oxide (6b). Complexes 5a and 5b are substituted at the non-peripheral (α) positions, whereas complexes 6a and 6b are substituted at the peripheral (β) positions. Cyclic voltammograms of all four complexes are similar, with three reversible reduction couples and three quasi-reversible to irreversible oxidations. The first two reductions are two-electron processes, confirmed by spectroelectrochemistry to be due to TiIVPc−2/TiIIPc−3 and TiIIPc−2/TiIPc−3 redox processes. Spectroelectrochemistry showed that upon oxidation, the molecule decomposes. Oxidation is expected to occur at the ring. Chronocoulometry confirmed two electron transfer at the first and second reduction steps; and a one electron transfer at the third reduction.
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- Date Issued: 2006
Synthesis and photophysical properties of octa-substituted phthalocyaninato oxotitanium (IV) derivatives
- Authors: Tau, Prudence , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/283881 , vital:55999 , xlink:href="https://doi.org/10.1142/S1088424606000399"
- Description: The synthesis, spectral and photophysical properties including fluorescence quenching of the following octa-substituted oxotitanium phthalocyanines are reported: 2,3,9,10,16,17,23,24-octaphenoxyphthalocyaninato titanium(IV) oxide, 2,3,9,10,16,17,23,24-[octakis(4-t-butylphenoxyphthalocyaninato)]titanium(IV) oxide, 2,3,9,10,16,17,23,24-{octakis[(4-benzyloxy)phenoxy]phthalocyaninato}titanium(IV) oxide and 2,3,9,10,16,17,23,24-octaphenylthiophthalocyaninato titanium(IV) oxide. The complexes are characterized by 1H NMR, IR and UV-vis spectroscopies. Their photophysical properties are presented where moderate fluorescence quantum yields (0.14-0.19) and lifetimes were determined. Varied triplet quantum yields were obtained and the triplet lifetimes (40-100 μs) were short.
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- Date Issued: 2006
Teacher-community cooperation to promote sustainability of wetlands in Kenya
- Authors: Ndaruga, Ayub M , Irwin, Patrick R
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/373860 , vital:66728 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122727"
- Description: This study was undertaken with 83 teachers from 54 primary schools in Kenya. Its purpose was to establish how teachers relate with the local community and how they harness this interaction to promote sustainability of wetlands within their locality. Data were collected using questionnaires, interviews and observation. Results of the study indicated that teachers acknowledge the value of, and threats to, their local wetlands. Some teachers reported interacting and engaging in diverse activities with members of the community to conserve the local wetlands. Forums for interaction and action mentioned by the teachers included public baraza, women’s groups, church, youth groups, local community, parents’ meetings and environmental days. Use of these forums differed. The approaches used to involve the community in awareness and action ranged from theoretical arguments to visits to wetlands, use of wetland resources, ecomanagement and political action. The responses by teachers revealed lack of engagement with the real local wetland problems. This study demonstrated existence of a potential but under-utilised opportunity that can be harnessed by environmental education programmes to champion the sustainability of wetlands.
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- Date Issued: 2006
The Condictio Indebiti and Unjust Factors (1)
- Authors: Glover, Graham B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186869 , vital:44541 , xlink:href="file:///C:/Users/User/Downloads/69THRHR419%20(2).pdf"
- Description: Since the Supreme Court of Appeal has continued to avoid taking the step of recognising a general enrichment action,' the traditional enrichment actions of the common law remain fundamentally important to the operation of the law of unjustified enrichment in South Africa. Most significant of these is the condictio indebiti, which is probably the most well-known and liberally utilised enrichment action in South African law.2 In this article, the nature and scope of this condictio will be examined, and it will be shown that it has grown beyond its notionally traditional role of reversing payments or transfers made unjustifiably by mistake, to include causes of action in duress and protest. The implications of this for the condictio, as well as for the foundations of our enrichment law will then be examined, with reference to the two leading schools of enrichment law: the civilian school, typified by German law, and the common-law school, typified by English law.
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- Date Issued: 2006
The Condictio Indebiti and Unjust Factors (2)
- Authors: Glover, Graham B
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186880 , vital:44544 , xlink:href="///C:/Users/User/Downloads/69THRHR561%20(1).pdf"
- Description: Since the Supreme Court of Appeal has continued to avoid taking the step of recognising a general enrichment action,' the traditional enrichment actions of the common law remain fundamentally important to the operation of the law of unjustified enrichment in South Africa. Most significant of these is the condictio indebiti, which is probably the most well-known and liberally utilised enrichment action in South African law.2 In this article, the nature and scope of this condictio will be examined, and it will be shown that it has grown beyond its notionally traditional role of reversing payments or transfers made unjustifiably by mistake, to include causes of action in duress and protest. The implications of this for the condictio, as well as for the foundations of our enrichment law will then be examined, with reference to the two leading schools of enrichment law: the civilian school, typified by German law, and the common-law school, typified by English law.
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- Date Issued: 2006
The effect of Ge, Si and Sn phthalocyanine photosensitizers on cell proliferation and viability of human oesophageal carcinoma cells
- Authors: Seotsanyana-Mokhosi, Itumeleng , Kresfelder, Tina , Abrahamse, Heidi , Nyokong, Tebello
- Date: 2006
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/286115 , vital:56241 , xlink:href="https://doi.org/10.1016/j.jphotobiol.2005.12.004"
- Description: The photodynamic activity of water soluble mixed sulfonated metallophthalocyanines complexes: GePcSmix, SnPcSmix and SiPcSmix on human oesophageal carcinoma (SNO) cells are reported, and compared with the activity of the unmetallated H2PcSmix and of the newly synthesized water soluble adjacently substituted binaphthalo phthalocyanine (complex 3). The alkaline phosphate (ALP) showed damage to the cell membrane in the presence of complex 3 without irradiation. The GePcSmix complex caused a relatively large increase in inflammation and a high intracellular ATP.
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- Date Issued: 2006