- Title
- Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles
- Creator
- Osifeko, Olawale L, Uddin, Imran, Mashazi, Philani N, Nyokong, Tebello
- Subject
- To be catalogued
- Date
- 2016
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/189121
- Identifier
- vital:44818
- Identifier
- xlink:href="https://doi.org/10.1039/C5NJ01922B"
- Description
- An AB3 type photosensitiser, consisting of 4-pyridylsulfanyl units (denoted as B3) and one aminophenoxy (denoted as A) group (complex 3) was synthesized. Complex 3 was then quaternized to form complex 4. The aminophenoxy substituent of complex 3 was used for the formation of the amide linkage with the carboxylic functionalised magnetic nanoparticles. Complexes 3 and 4 and their conjugates with magnetic nanoparticles were then used for photodynamic antimicrobial chemotherapy on E. coli. The cationic photosensitiser 4 showed a high efficiency for photodynamic antimicrobial chemotherapy at a very low concentration compared to its conjugate on E. coli.
- Format
- computer, online resource, application/pdf, 1 online resource (12 pages), pdf
- Publisher
- Royal Society of Chemistry
- Language
- English
- Relation
- New Journal of Chemistry, Osifeko, O.L., Uddin, I., Mashazi, P.N. and Nyokong, T., 2016. Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles. New Journal of Chemistry, 40(3), pp.2710-2721, New Journal of Chemistry volume 40 number 3 p. 2710 2016 1369-9261
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Royal Society of Chemistry Terms and Conditions Statement (https://0-www.rsc.org.wam.seals.ac.za/help-legal/)
- Rights
- Open Access
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Collections
Mashazi, Philani N (Associate Prof)
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines.pdf | 4 MB | Adobe Acrobat PDF | View Details Download |