- Title
- The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3
- Creator
- Mautsa, Nicodemus, Prinsloo, Earl, Tastan Bishop, Özlem, Blatch, Gregory L
- Date
- 2011
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/148082
- Identifier
- vital:38708
- Identifier
- DOI: 10.1002/jmr.1111
- Description
- The protein inhibitor of activated signal transducer and activator of transcription 3 (PIAS3) regulates the transcriptional activity of signal transducer and activator of transcription 3 (STAT3) which regulates transcription of genes involved in cell growth, proliferation and apoptosis. The conserved proline, isoleucine, asparagine, isoleucine, threonine (PINIT) domain of PIAS3 is thought to promote STAT3–PIAS3 interaction.
- Format
- 9 pages, pdf
- Language
- English
- Relation
- Journal of Molecular Recognition, Mautsa, N., Prinsloo, E., Bishop, Ö.T. and Blatch, G.L., 2011. The PINIT domain of PIAS3: structure‐function analysis of its interaction with STAT3. Journal of Molecular Recognition, 24(5), pp.795-803., Journal of Molecular Recognition volume 24 number 5 795 803 June 2011 1099-1352
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Wiley Online Library Terms of Use statement (https://onlinelibrary.wiley.com/terms-and-conditions)
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