Women combatants and the liberation movements in South Africa
- Authors: Magadla, Siphokazi
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/298584 , vital:57718 , xlink:href="https://doi.org/10.1080/10246029.2015.1088645"
- Description: This article examines women's role as combatants in national liberation forces in South Africa. Three categories – guerrilla girls, combative mothers and the in-betweeners – are introduced to underscore the varied ways in which women have participated in combat within the national liberation movements. Factors such as age and one's ability to leave the country affected whether women could participate in combat as ‘guerrilla girls’ or if it limited them to fighting apartheid violence from home, or if there were women who can be defined as having fallen somewhere in between these categories. These categories are used to theorise women's combat roles in the anti-apartheid struggle, thus broadening and challenging the dominant notions of combat that often hide women's contributions in war. In this regard, different periods of struggle, physical location, as well as age, determined the methods of activism available to men and women.
- Full Text:
- Authors: Magadla, Siphokazi
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/298584 , vital:57718 , xlink:href="https://doi.org/10.1080/10246029.2015.1088645"
- Description: This article examines women's role as combatants in national liberation forces in South Africa. Three categories – guerrilla girls, combative mothers and the in-betweeners – are introduced to underscore the varied ways in which women have participated in combat within the national liberation movements. Factors such as age and one's ability to leave the country affected whether women could participate in combat as ‘guerrilla girls’ or if it limited them to fighting apartheid violence from home, or if there were women who can be defined as having fallen somewhere in between these categories. These categories are used to theorise women's combat roles in the anti-apartheid struggle, thus broadening and challenging the dominant notions of combat that often hide women's contributions in war. In this regard, different periods of struggle, physical location, as well as age, determined the methods of activism available to men and women.
- Full Text:
Women’s micro-narratives of the process of abortion decision-making: justifying the decision to have an abortion
- Mavuso, Jabulile M-J J, Macleod, Catriona I
- Authors: Mavuso, Jabulile M-J J , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143893 , vital:38292 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: What is missing from abortion research is research that explores women’s narratives of the processes of abortion decision-making in a way that acknowledges the constraints placed on ‘choice’. This study sought to explore, using Foucauldian feminist post-structuralism and a narrative-discursive approach, women’s micro-narratives of the abortion decision-making process. Purposive sampling was used to recruit a total of 25 participants from three abortion facilities in the Eastern Cape. Participants were unmarried ‘Black’ women between the ages of 19 and 35, and were mostly unemployed. Narrative interviews were done with the women. Analysis revealed an over-arching narrative in which women described the abortion decision as something that they were ‘forced’ into by their circumstances. To construct this narrative, women justified the decision to have an abortion by drawing on discourses that normalise certain practices located within the husband-wife and parent-child axes and make the pregnancy a problematic, unsupported and unsupportable one. Gendered and generational power relations reinforced this and contributed to the obstruction of reproductive justice.
- Full Text:
- Authors: Mavuso, Jabulile M-J J , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143893 , vital:38292 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: What is missing from abortion research is research that explores women’s narratives of the processes of abortion decision-making in a way that acknowledges the constraints placed on ‘choice’. This study sought to explore, using Foucauldian feminist post-structuralism and a narrative-discursive approach, women’s micro-narratives of the abortion decision-making process. Purposive sampling was used to recruit a total of 25 participants from three abortion facilities in the Eastern Cape. Participants were unmarried ‘Black’ women between the ages of 19 and 35, and were mostly unemployed. Narrative interviews were done with the women. Analysis revealed an over-arching narrative in which women described the abortion decision as something that they were ‘forced’ into by their circumstances. To construct this narrative, women justified the decision to have an abortion by drawing on discourses that normalise certain practices located within the husband-wife and parent-child axes and make the pregnancy a problematic, unsupported and unsupportable one. Gendered and generational power relations reinforced this and contributed to the obstruction of reproductive justice.
- Full Text:
Young people’s use of ‘peer pressure/normalization’ as discursive resources to justify gendered youth sexualities: implications for Life Orientation sexuality education programmes
- Jearey-Graham, Nicola, Macleod, Catriona I
- Authors: Jearey-Graham, Nicola , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143749 , vital:38279 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: ‘Peer pressure’ has been associated in the scientific literature with a range of risky sexual behaviors, thereby undermining safe sex messages delivered in Life Orientation (LO) classes. LO texts warn against peer pressure. Taking a discursive psychology perspective, we show how young people, in contrast, use the discourses of ‘peer pressure to have sex’ and ‘peer normalization of sex’ to justify youth sexual activity. Using data from focus group discussions about youth sexualities with students at a Further Education and Training College in South Africa, we show how participants outlined a need for young people to be socially recognizable through engaging in, and being able to talk about sex, and how they implicated peer norms in governing individual sexual behavior. Both discourses pointed to a gendering of sexual norms. The deployment of these discourses by young people themselves has implications for Life Orientation programmes. Nuanced engagement with ‘peer group’ narratives is indicated.
- Full Text:
- Authors: Jearey-Graham, Nicola , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143749 , vital:38279 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: ‘Peer pressure’ has been associated in the scientific literature with a range of risky sexual behaviors, thereby undermining safe sex messages delivered in Life Orientation (LO) classes. LO texts warn against peer pressure. Taking a discursive psychology perspective, we show how young people, in contrast, use the discourses of ‘peer pressure to have sex’ and ‘peer normalization of sex’ to justify youth sexual activity. Using data from focus group discussions about youth sexualities with students at a Further Education and Training College in South Africa, we show how participants outlined a need for young people to be socially recognizable through engaging in, and being able to talk about sex, and how they implicated peer norms in governing individual sexual behavior. Both discourses pointed to a gendering of sexual norms. The deployment of these discourses by young people themselves has implications for Life Orientation programmes. Nuanced engagement with ‘peer group’ narratives is indicated.
- Full Text:
‘Charmer boys’ and ‘cream girls’: children’s construction of the (hetero)sexual self through football and implications for Life Orientation sexuality education
- Authors: Mayeza, Emmanuel
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143760 , vital:38280 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: Due to the adult-centric ‘common-sense’ view of primary school children as non-sexual, research on schooling, gender and sexuality in South Africa rarely addresses primary schools. In contrast, this paper explores how nine-to-ten year-old children in a working-class, township primary school near Durban (hetero)sexualise their gendered identities through football. By illuminating the different ways in which the young children in the study construct themselves as both gendered and sexual beings in their everyday playground and sometimes ‘underground’ cultures at the school, the paper calls into question the ‘common-sense’ discourse of childhood which (re)produces primary schools as sexuallyfree contexts. Findings raise pertinent implications that call for the (re)conceptualisation of children; from being seen simply through the discourse of sexual innocence to being conceptualised as people who are capable of expressing sexual agency. This, in turn, calls for the development of new ways of working with the young children in Life Orientation sexuality and HIV/AIDS education which are empathetic and sympathetic to the children’s own constructions of themselves as both gendered and sexual beings.
- Full Text:
- Authors: Mayeza, Emmanuel
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143760 , vital:38280 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: Due to the adult-centric ‘common-sense’ view of primary school children as non-sexual, research on schooling, gender and sexuality in South Africa rarely addresses primary schools. In contrast, this paper explores how nine-to-ten year-old children in a working-class, township primary school near Durban (hetero)sexualise their gendered identities through football. By illuminating the different ways in which the young children in the study construct themselves as both gendered and sexual beings in their everyday playground and sometimes ‘underground’ cultures at the school, the paper calls into question the ‘common-sense’ discourse of childhood which (re)produces primary schools as sexuallyfree contexts. Findings raise pertinent implications that call for the (re)conceptualisation of children; from being seen simply through the discourse of sexual innocence to being conceptualised as people who are capable of expressing sexual agency. This, in turn, calls for the development of new ways of working with the young children in Life Orientation sexuality and HIV/AIDS education which are empathetic and sympathetic to the children’s own constructions of themselves as both gendered and sexual beings.
- Full Text:
‘It's just taking our souls back’: discourses of apartheid and race
- Authors: Bock, Zannie , Hunt, Sally
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124888 , vital:35707 , https://doi.org/10.2989/16073614.2015.1056196
- Description: Although apartheid officially ended in 1994, the issue of race as a primary identity marker has continued to permeate many aspects of private and public life in post-apartheid South Africa. This paper seeks to understand how youth at two South African tertiary institutions position themselves in relation to race and the apartheid past. Our data include four focus group interviews from two universities, one which can be described as historically ‘black’ and the other as historically ‘white’. Given the complex nature of the data, we elected to use a combination of corpus linguistics and discourse analysis as our methodological approach. We explore how words such as black, white, coloured, they, we, us and them feature in the interviews. Our analysis shows that the positioning by the interviewees reflects a complexity and ambivalence that is at times contradictory although several broader discourse patterns can be distilled. In particular, we argue, that all groups employ a range of discursive strategies so as to resist being positioned in the historical positions of ‘victim’ and ‘perpetrator’. Our paper reflects on these findings as well as what they offer us as we attempt to chart new discourses of the future.
- Full Text:
- Authors: Bock, Zannie , Hunt, Sally
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124888 , vital:35707 , https://doi.org/10.2989/16073614.2015.1056196
- Description: Although apartheid officially ended in 1994, the issue of race as a primary identity marker has continued to permeate many aspects of private and public life in post-apartheid South Africa. This paper seeks to understand how youth at two South African tertiary institutions position themselves in relation to race and the apartheid past. Our data include four focus group interviews from two universities, one which can be described as historically ‘black’ and the other as historically ‘white’. Given the complex nature of the data, we elected to use a combination of corpus linguistics and discourse analysis as our methodological approach. We explore how words such as black, white, coloured, they, we, us and them feature in the interviews. Our analysis shows that the positioning by the interviewees reflects a complexity and ambivalence that is at times contradictory although several broader discourse patterns can be distilled. In particular, we argue, that all groups employ a range of discursive strategies so as to resist being positioned in the historical positions of ‘victim’ and ‘perpetrator’. Our paper reflects on these findings as well as what they offer us as we attempt to chart new discourses of the future.
- Full Text:
‘Victim’ or ‘survivor’?: language, identity and ethics revisited
- Barker, Kim, Macleod, Catriona I
- Authors: Barker, Kim , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143738 , vital:38278 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: Initially in feminist circles, and subsequently in more common usage, the term ‘survivor’ came to signify those who have been (sexually) violated and live on, and even thrive. The passivity implied by the term ‘victim’ therefore gave way to the more agentic connotations of ‘survivor’. However, neither term adequately captures the complexity and fluidity of subject positions taken up by and ascribed to women who have been subjected to sexual violence. The selection of an inadequate word is not neutral: each identifier calls forth particular identity constructions which have real effects. Reducing women’s experiences to one pole of this simple binary can diminish and totalise those experiences. In this paper we re-consider the use of these terms with reference to research conducted with protestors participating in an annual anti-rape protest held at Rhodes University, Grahamstown, South Africa. We focus on the perspectives of women who are ‘survivors’ of sexual violence.
- Full Text:
- Authors: Barker, Kim , Macleod, Catriona I
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143738 , vital:38278 , https://ischp.files.wordpress.com/2015/08/ischp_2015_abstract_booklet.pdf
- Description: Initially in feminist circles, and subsequently in more common usage, the term ‘survivor’ came to signify those who have been (sexually) violated and live on, and even thrive. The passivity implied by the term ‘victim’ therefore gave way to the more agentic connotations of ‘survivor’. However, neither term adequately captures the complexity and fluidity of subject positions taken up by and ascribed to women who have been subjected to sexual violence. The selection of an inadequate word is not neutral: each identifier calls forth particular identity constructions which have real effects. Reducing women’s experiences to one pole of this simple binary can diminish and totalise those experiences. In this paper we re-consider the use of these terms with reference to research conducted with protestors participating in an annual anti-rape protest held at Rhodes University, Grahamstown, South Africa. We focus on the perspectives of women who are ‘survivors’ of sexual violence.
- Full Text:
“Ha! Relationships? I only shout at them!”: Strategic management of discordant rapport in an African small business context
- Lauriks, Sanne, Siebörger, Ian, de Vos, Mark
- Authors: Lauriks, Sanne , Siebörger, Ian , de Vos, Mark
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/385338 , vital:68009 , xlink:href="https://doi.org/10.1515/pr-2015-0002"
- Description: This study demonstrates how and why interactants at a tyre fitment centre in Grahamstown, South Africa, manage discordant interpersonal relationships in strategic ways. Individuals in a post-apartheid small business respond to their social and economic context and exercise agency to their advantage in doing so. This study draws on linguistic ethnography (Rampton 2007) and the Rapport Management Framework (RMF, Spencer-Oatey 2000b, 2011), itself a development of politeness theory (Brown and Levinson 1987). An initial RMF analysis ran into difficulties around interactions that at first glance appeared to be oriented toward Rapport Challenge and Neglect. Upon closer examination, it appeared that discordant rapport was being actively maintained in this business. This led us to address underdeveloped areas of RMF that were not responsive enough to describe naturally occurring small business interactions, and propose an Enhanced Rapport Management Framework to overcome its inadequacies. We conclude that people may deliberately maintain discordant relationships when it is in their best interests to do so. Thus, contrary to a common-sense belief that harmonious social relations are an intrinsic good, we found that promoting discordant social relations can be understood as a rational response to individuals’ social and economic contexts, particularly in conditions such as those in many postcolonial African societies.
- Full Text:
- Authors: Lauriks, Sanne , Siebörger, Ian , de Vos, Mark
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/385338 , vital:68009 , xlink:href="https://doi.org/10.1515/pr-2015-0002"
- Description: This study demonstrates how and why interactants at a tyre fitment centre in Grahamstown, South Africa, manage discordant interpersonal relationships in strategic ways. Individuals in a post-apartheid small business respond to their social and economic context and exercise agency to their advantage in doing so. This study draws on linguistic ethnography (Rampton 2007) and the Rapport Management Framework (RMF, Spencer-Oatey 2000b, 2011), itself a development of politeness theory (Brown and Levinson 1987). An initial RMF analysis ran into difficulties around interactions that at first glance appeared to be oriented toward Rapport Challenge and Neglect. Upon closer examination, it appeared that discordant rapport was being actively maintained in this business. This led us to address underdeveloped areas of RMF that were not responsive enough to describe naturally occurring small business interactions, and propose an Enhanced Rapport Management Framework to overcome its inadequacies. We conclude that people may deliberately maintain discordant relationships when it is in their best interests to do so. Thus, contrary to a common-sense belief that harmonious social relations are an intrinsic good, we found that promoting discordant social relations can be understood as a rational response to individuals’ social and economic contexts, particularly in conditions such as those in many postcolonial African societies.
- Full Text:
A high-level architecture for efficient packet trace analysis on gpu co-processors
- Nottingham, Alastair, Irwin, Barry V W
- Authors: Nottingham, Alastair , Irwin, Barry V W
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429572 , vital:72623 , 10.1109/ISSA.2013.6641052
- Description: This paper proposes a high-level architecture to support efficient, massively parallel packet classification, filtering and analysis using commodity Graphics Processing Unit (GPU) hardware. The proposed architecture aims to provide a flexible and efficient parallel packet processing and analysis framework, supporting complex programmable filtering, data mining operations, statistical analysis functions and traffic visualisation, with minimal CPU overhead. In particular, this framework aims to provide a robust set of high-speed analysis functionality, in order to dramatically reduce the time required to process and analyse extremely large network traces. This architecture derives from initial research, which has shown GPU co-processors to be effective in accelerating packet classification to up to tera-bit speeds with minimal CPU overhead, far exceeding the bandwidth capacity between standard long term storage and the GPU device. This paper provides a high-level overview of the proposed architecture and its primary components, motivated by the results of prior research in the field.
- Full Text:
- Authors: Nottingham, Alastair , Irwin, Barry V W
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429572 , vital:72623 , 10.1109/ISSA.2013.6641052
- Description: This paper proposes a high-level architecture to support efficient, massively parallel packet classification, filtering and analysis using commodity Graphics Processing Unit (GPU) hardware. The proposed architecture aims to provide a flexible and efficient parallel packet processing and analysis framework, supporting complex programmable filtering, data mining operations, statistical analysis functions and traffic visualisation, with minimal CPU overhead. In particular, this framework aims to provide a robust set of high-speed analysis functionality, in order to dramatically reduce the time required to process and analyse extremely large network traces. This architecture derives from initial research, which has shown GPU co-processors to be effective in accelerating packet classification to up to tera-bit speeds with minimal CPU overhead, far exceeding the bandwidth capacity between standard long term storage and the GPU device. This paper provides a high-level overview of the proposed architecture and its primary components, motivated by the results of prior research in the field.
- Full Text:
A kernel-driven framework for high performance internet routing simulation
- Herbert, Alan, Irwin, Barry V W
- Authors: Herbert, Alan , Irwin, Barry V W
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429585 , vital:72624 , 10.1109/ISSA.2013.6641048
- Description: The ability to provide the simulation of packets traversing an internet path is an integral part of providing realistic simulations for network training, and cyber defence exercises. This paper builds on previous work, and considers an in-kernel approach to solving the routing simulation problem. The inkernel approach is anticipated to allow the framework to be able to achieve throughput rates of 1GB/s or higher using commodity hardware. Processes that run outside the context of the kernel of most operating system require context switching to access hardware and kernel modules. This leads to considerable delays in the processes, such as network simulators, that frequently access hardware such as hard disk accesses and network packet handling. To mitigate this problem, as experienced with earlier implementations, this research looks towards implementing a kernel module to handle network routing and simulation within a UNIX based system. This would remove delays incurred from context switching and allows for direct access to the hardware components of the host.
- Full Text:
- Authors: Herbert, Alan , Irwin, Barry V W
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429585 , vital:72624 , 10.1109/ISSA.2013.6641048
- Description: The ability to provide the simulation of packets traversing an internet path is an integral part of providing realistic simulations for network training, and cyber defence exercises. This paper builds on previous work, and considers an in-kernel approach to solving the routing simulation problem. The inkernel approach is anticipated to allow the framework to be able to achieve throughput rates of 1GB/s or higher using commodity hardware. Processes that run outside the context of the kernel of most operating system require context switching to access hardware and kernel modules. This leads to considerable delays in the processes, such as network simulators, that frequently access hardware such as hard disk accesses and network packet handling. To mitigate this problem, as experienced with earlier implementations, this research looks towards implementing a kernel module to handle network routing and simulation within a UNIX based system. This would remove delays incurred from context switching and allows for direct access to the hardware components of the host.
- Full Text:
Deep Routing Simulation
- Irwin, Barry V W, Herbert, Alan
- Authors: Irwin, Barry V W , Herbert, Alan
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430353 , vital:72685 , https://www.academic-bookshop.com/ourshop/prod_2546879-ICIW-2013-8th-International-Conference-on-Information-Warfare-and-Security.html
- Description: This paper discusses a dataset of some 16 million packets targeting port 445/tcp collected by a network telescope utilising a /24 netblock in South African IP address space. An initial overview of the collected data is provided. This is followed by a detailed analysis of the packet characteristics observed, including size and TTL. The peculiarities of the observed target selection and the results of the flaw in the Conficker worm's propagation algorithm are presented. An analysis of the 4 million observed source hosts is reported, grouped by both packet counts and the number of distinct hosts per network address block. Address blocks of size /8, 16 and 24 are used for groupings. The localisation, by geographic region and numerical proximity, of high ranking aggregate netblocks is highlighted. The observed shift in geopolitical origins observed during the evolution of the Conficker worm is also discussed. The paper concludes with some overall analyses, and consideration of the application of network telescopes to the monitoring of such outbreaks in the future.
- Full Text:
- Authors: Irwin, Barry V W , Herbert, Alan
- Date: 2013
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430353 , vital:72685 , https://www.academic-bookshop.com/ourshop/prod_2546879-ICIW-2013-8th-International-Conference-on-Information-Warfare-and-Security.html
- Description: This paper discusses a dataset of some 16 million packets targeting port 445/tcp collected by a network telescope utilising a /24 netblock in South African IP address space. An initial overview of the collected data is provided. This is followed by a detailed analysis of the packet characteristics observed, including size and TTL. The peculiarities of the observed target selection and the results of the flaw in the Conficker worm's propagation algorithm are presented. An analysis of the 4 million observed source hosts is reported, grouped by both packet counts and the number of distinct hosts per network address block. Address blocks of size /8, 16 and 24 are used for groupings. The localisation, by geographic region and numerical proximity, of high ranking aggregate netblocks is highlighted. The observed shift in geopolitical origins observed during the evolution of the Conficker worm is also discussed. The paper concludes with some overall analyses, and consideration of the application of network telescopes to the monitoring of such outbreaks in the future.
- Full Text:
Synthesis of phthalocyanine conjugates with gold nanoparticles and liposomes for photodynamic therapy
- Nombona, Nolwazi, Maduray, Kaminee, Antunes, Edith M, Karsten, Aletta, Nyokong, Tebello
- Authors: Nombona, Nolwazi , Maduray, Kaminee , Antunes, Edith M , Karsten, Aletta , Nyokong, Tebello
- Date: 2012
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/245798 , vital:51406 , xlink:href="https://doi.org/10.1016/j.jphotobiol.2011.11.007"
- Description: The efficiency of [2,9,17,23-tetrakis-(1,6-hexanedithiol)phthalocyaninato]zinc(II) as a photodynamic therapy (PDT) agent was investigated. This compound belongs to the second generation of photosensitizers currently tested for the cellular photo-damage of cancer cells. The production of reactive oxygen species (ROS) and phototoxicity of the photosensitizer were assessed. Healthy fibroblast cells and breast cancer (MCF-7) cells were treated with either free phthalocyanine or phthalocyanine bound to either gold nanoparticles or encapsulated in liposomes. Cell viability studies showed the optimum phototoxic effect on non-malignant cells to be 4.5 J cm−2. The PDT effect of the liposome bound phthalocyanine showed extensive damage of the breast cancer cells. Gold nanoparticles only showed a modest improvement in PDT activity.
- Full Text:
- Authors: Nombona, Nolwazi , Maduray, Kaminee , Antunes, Edith M , Karsten, Aletta , Nyokong, Tebello
- Date: 2012
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/245798 , vital:51406 , xlink:href="https://doi.org/10.1016/j.jphotobiol.2011.11.007"
- Description: The efficiency of [2,9,17,23-tetrakis-(1,6-hexanedithiol)phthalocyaninato]zinc(II) as a photodynamic therapy (PDT) agent was investigated. This compound belongs to the second generation of photosensitizers currently tested for the cellular photo-damage of cancer cells. The production of reactive oxygen species (ROS) and phototoxicity of the photosensitizer were assessed. Healthy fibroblast cells and breast cancer (MCF-7) cells were treated with either free phthalocyanine or phthalocyanine bound to either gold nanoparticles or encapsulated in liposomes. Cell viability studies showed the optimum phototoxic effect on non-malignant cells to be 4.5 J cm−2. The PDT effect of the liposome bound phthalocyanine showed extensive damage of the breast cancer cells. Gold nanoparticles only showed a modest improvement in PDT activity.
- Full Text:
Histological validation of gonadal macroscopic staging criteria for Labeo cylindricus (Pisces: Cyprinidae)
- Booth, Anthony J, Weyl, Olaf L F
- Authors: Booth, Anthony J , Weyl, Olaf L F
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124593 , vital:35634 , https://doi.org/10.1080/15627020.2000.11657094
- Description: Histological examination of gametogenesis revealed that the current staging criteria used to assess gonadal recrudescence of the redeye labeo, Labeo cylindricus, were adequate. Gametogenesis was qualitatively similar to that of freshwater teleosts with a clearly defined seasonal reproductive cycle. L. cylindricus undergoes seasonal gross morphological and cytological gonadal changes with previtellogenesis dominating during the winter, vitellogenic development during spring and summer culminating in large-scale spawning at the end of summer. Post-spawning mass atresia of oocytes was evident in autumn. The histological data presented support macroscopical evidence that L. cylindricus is a synchronous iteroparous spawner, reproducing over a short period each year throughout its life-span.
- Full Text:
- Authors: Booth, Anthony J , Weyl, Olaf L F
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124593 , vital:35634 , https://doi.org/10.1080/15627020.2000.11657094
- Description: Histological examination of gametogenesis revealed that the current staging criteria used to assess gonadal recrudescence of the redeye labeo, Labeo cylindricus, were adequate. Gametogenesis was qualitatively similar to that of freshwater teleosts with a clearly defined seasonal reproductive cycle. L. cylindricus undergoes seasonal gross morphological and cytological gonadal changes with previtellogenesis dominating during the winter, vitellogenic development during spring and summer culminating in large-scale spawning at the end of summer. Post-spawning mass atresia of oocytes was evident in autumn. The histological data presented support macroscopical evidence that L. cylindricus is a synchronous iteroparous spawner, reproducing over a short period each year throughout its life-span.
- Full Text:
Synthesis, photophysical and photochemical properties of octa-substituted antimony phthalocyanines
- Modibane, Desmond Kwena, Nyokong, Tebello
- Authors: Modibane, Desmond Kwena , Nyokong, Tebello
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/264226 , vital:53711 , xlink:href="https://doi.org/10.1016/j.poly.2008.11.052"
- Description: This work reports on the synthesis and photophysicochemical parameters of unsubstituted [SbIIIPc]+I3- and octa-phenoxy ([SbIIIOPPc]+I3-) and -4-t-butylphenoxy ([SbIIIOTBPPc]+I3-) substituted antimony phthalocyanines. Photophysical and photochemical properties were studied for these complexes in dimethylsulfoxide, dimethylformamide and toluene. The excitation spectra of oxidized antimony (Sb(V)Pc) derivates were similar to absorption spectra. Low fluorescence quantum yields, high triplet quantum yields and low triplet lifetimes were observed as the result of heavy atom (antimony ion).
- Full Text:
- Authors: Modibane, Desmond Kwena , Nyokong, Tebello
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/264226 , vital:53711 , xlink:href="https://doi.org/10.1016/j.poly.2008.11.052"
- Description: This work reports on the synthesis and photophysicochemical parameters of unsubstituted [SbIIIPc]+I3- and octa-phenoxy ([SbIIIOPPc]+I3-) and -4-t-butylphenoxy ([SbIIIOTBPPc]+I3-) substituted antimony phthalocyanines. Photophysical and photochemical properties were studied for these complexes in dimethylsulfoxide, dimethylformamide and toluene. The excitation spectra of oxidized antimony (Sb(V)Pc) derivates were similar to absorption spectra. Low fluorescence quantum yields, high triplet quantum yields and low triplet lifetimes were observed as the result of heavy atom (antimony ion).
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