Colonised minds?: post-development theory and the desirability of development in Africa
- Authors: Matthews, Sally
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142213 , vital:38059 , DOI: 10.1080/01436597.2017.1279540
- Description: While post-development theory is very concerned with the ways in which development has impacted upon the countries of the Global South, there has been relatively little written on post-development theory from an African perspective. This paper identifies some of the ways in which post-development theory fails to adequately understand the African experience of development. In particular, I explore the difficulty that post-development theory confronts when faced with the continued desire on the part of many people in Africa for development.
- Full Text:
- Date Issued: 2017
Counting on demographic equity to transform institutional cultures at historically white South African universities?:
- Authors: Booi, Masixole , Vincent, Louise , Liccardo, Sabrina
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141946 , vital:38018 , DOI: 10.1080/07294360.2017.1289155
- Description: The post-apartheid higher education transformation project is faced with the challenge of recruiting and retaining black academics and other senior staff. But when we shift the focus from participation rates to equality–inequality within historically white universities (HWUs), then the discourse changes from demographic equity and redress to institutional culture and diversity. HWUs invoke the need to maintain their position as leading higher education institutions globally, and notions of ‘quality’ and ‘excellence’ have emerged as discursive practices, which serve to perpetuate exclusion. The question then arises as to which forms of capital comprise the Gold Standard at HWUs? Several South African universities have responded to the challenge of recruiting and retaining black academics by initiating programmes for the ‘accelerated development’ of these candidates.
- Full Text:
- Date Issued: 2017
Decoupled reciprocal subsidies of biomass and fatty acids in fluxes of invertebrates between a temperate river and the adjacent land:
- Authors: Moyo, Sydney , Chari, Lenin D , Villet, Martin H , Richoux, Nicole B
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140843 , vital:37923 , DOI: 10.1007/s00027-017-0529-0
- Description: Streams and riparian areas are tightly coupled through reciprocal trophic subsidies, and there is evidence that these subsidies affect consumers in connected ecosystems. Most studies of subsidies consider only their quantity and not their quality. We determined the bidirectional exchange of organisms between the Kowie River and its riparian zone in South Africa using floating pyramidal traps (to measure insect emergence) and pan traps (to capture infalling invertebrates).
- Full Text:
- Date Issued: 2017
Forensic entomotoxicology revisited: towards professional standardisation of study designs
- Authors: da Silva, Erica I T , Wilhelmi, Brendan S , Villet, Martin H
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140819 , vital:37921 , DOI: 10.1007/s00414-017-1603-9
- Description: Forensic entomotoxicology is the use of insects as evidence of whether a toxicant is present in an environment such as a corpse, river or landscape. The earliest overtly forensic study was published in 1977, and since then, at least 63 papers have been published, most of them focused on the detection of toxicants in insects or on effects of toxicants on diverse insect indicator taxa. A comprehensive review of the published literature revealed various inconsistencies between studies that could be addressed by introducing standard protocols for such studies. These protocols could include selecting widespread and common model organisms (such as Lucilia sericata, Calliphora vicina, Chrysomya megacephala and Dermestes maculatus) and model toxicants (e.g. morphine and amitriptyline) to build up comparative databases; developing a standard matrix for use as a feeding substrate; setting guidelines for statistically adequate sample sizes; and deploying more sophisticated analytical methods from the general field of toxicology.
- Full Text:
- Date Issued: 2017
MD-TASK: a software suite for analyzing molecular dynamics trajectories
- Authors: Brown, David K , Penkler, David L , Amamuddy, Olivier S , Ross, Caroline J , Atilgan, Ali R , Atilgan, Canan , Tastan Bishop, Özlem
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125138 , vital:35735 , https://doi.10.1093/bioinformatics/btx349
- Description: Molecular dynamics (MD) determines the physical motions of atoms of a biological macromolecule in a cell-like environment and is an important method in structural bioinformatics. Traditionally, measurements such as root mean square deviation, root mean square fluctuation, radius of gyration, and various energy measures have been used to analyze MD simulations. Here, we present MD-TASK, a novel software suite that employs graph theory techniques, perturbation response scanning, and dynamic cross-correlation to provide unique ways for analyzing MD trajectories.
- Full Text:
- Date Issued: 2017
Pessimistic assessment of white shark population status in South Africa: comment on Andreotti et al.(2016)
- Authors: Irion, Dylan T , Noble, Leslie R , Kock, Alison A , Gennari, Enrico , Dicken, Matthew L , Hewitt, Adrian M , Towner, Alison V , Booth, Anthony J , Smale, Malcolm J , Cliff, Geremy
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/${Handle} , vital:35799 , https://doi.10.3354/meps12283
- Description: Andreotti et al. (2016; Mar Ecol Prog Ser 552:241−253) estimate an abundance (N) of 438 white sharks Carcharodon carcharias and a contemporary effective population size (CNe) of 333 individuals along the South African coast. N was estimated by using a mark-recapture analysis of photographic identification records from a single aggregation site (Gansbaai). CNe was calculated based on the levels of pairwise linkage disequilibrium of genetic material collected from 4 aggregation sites across approximately 965 km of South African coastline. However, due to the complex stock structure of white sharks and the model assumptions made by Andreotti et al. (2016), the conclusions drawn cannot be supported by their methods and data.
- Full Text:
- Date Issued: 2017
Rhodes University Graduation Ceremony 2017
- Authors: Rhodes University
- Date: 2017
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/58067 , vital:27061
- Description: 2017 Graduation Ceremony, Umsitho Wothweso-Zidanga, Gradeplegtigheid [at] 1820 Settlers National Monument, Thursday, 20 April until Saturday, 22 April 2017.
- Full Text:
- Date Issued: 2017
Synthesis, characterisation and evaluation of benzoxaborole-based hybrids as antiplasmodial agents
- Authors: Gumbo, Maureen
- Date: 2017
- Subjects: Malaria Chemotherapy , Antimalarials , Boron compounds , Drug resistance , Plasmodium falciparum , Drug development
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/59193 , vital:27456
- Description: Malaria is a mosquito-borne disease, which continues to pose a threat to the entire humanity. About 40% of the world population is estimated to be at risk of infections by malaria. Despite efforts undertaken by scientific community, government entities and international organizations, malaria is still rampant. The major problem is drug resistance, where the Plasmodium spp have over the past decades developed drug resistance against available drugs. In order to counter this problem, novel antimalarial drugs that are efficacious and with novel mode of action are of great necessity. Benzoxaborole derivatives have been shown to exhibit promising antimalarial activity against Plasmodium falciparum strains. Previous studies reported on the compounds such as 6-(2- (alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles, which showed good antimalarial activity against both W7 and 3D7 strains without significant toxicity. On the other hand, chloroquine (CQ) and cinnamic acids have a wide variety of biological activity including antimalarial activity. Herein, a hybridisation strategy was employed to synthesise new CQ-benzoxaborole and cinnamoyl-benzoxaborole hybrids. CQ-Benzoxaborole 2.12a-c and cinnamoylbenzoxaborole 2.11a-g hydrid molecules were synthesised in low to good yields. Their structural identities were confirmed using conventional spectroscopic techniques (1H and 13C NMR, and mass spectrometry). CQ-benzoxaborole compounds, however, showed instability, and only 2.12b was used for in vitro biological assay and showed activity comparable to CQ. Furthermore, in vitro biological assay revealed that compounds 2.11a-g poorly inhibited the growth of P. falciparum parasites. Interestingly, these compounds, however, exhibited satisfactory activity against Trypanosoma brucei with IC50 = 0.052 μM for compound 2.11g. The cell cytotoxicity assay of all final compounds confirmed that all CQ-benzoxaborole 2.12b and cinnamoyl-benzoxaborole 2.11a-g hybrids were non-toxic against HeLa cell lines. However, efforts to further expand the structure-activity relationship (SAR) of CQbenzoxaborole by increasing the length of the linker with one extra carbon (Scheme 2.10) were not possible as an important precursor 6-formylbenzoxaborole 2.29 could not be synthesized in sufficient yields. , Thesis (MSc) -- Faculty of Faculty of Science, Chemistry, 2017
- Full Text:
- Date Issued: 2017
Multiple drivers of local (non-) compliance in community-cased marine resource management: case studies from the South Pacific
- Authors: Rohe, Janne R , Aswani, Shankar , Schlüter, Achim , Ferse, Sebastian C A
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70571 , vital:29676 , https://doi.org/10.3389/fmars.2017.00172
- Description: The outcomes of marine conservation and related management interventions depend to a large extent on people's compliance with these rule systems. In the South Pacific, community-based marine resource management (CBMRM) has gained wide recognition as a strategy for the sustainable management of marine resources. In current practice, CBMRM initiatives often build upon customary forms of marine governance, integrating scientific advice and management principles in collaboration with external partners. However, diverse socio-economic developments as well as limited legal mandates can challenge these approaches. Compliance with and effective (legally-backed) enforcement of local management strategies constitute a growing challenge for communities—often resulting in considerable impact on the success or failure of CBMRM. Marine management arrangements are highly dynamic over time, and similarly compliance with rule systems tends to change depending on context. Understanding the factors contributing to (non-) compliance in a given setting is key to the design and function of adaptive management approaches. Yet, few empirical studies have looked in depth into the dynamics around local (non-) compliance with local marine tenure rules under the transforming management arrangements. Using two case studies from Solomon Islands and Fiji, we investigate what drives local (non-) compliance with CBMRM and what hinders or supports its effective enforcement. The case studies reveal that non-compliance is mainly driven by: (1) diminishing perceived legitimacy of local rules and rule-makers; (2) increased incentives to break rules due to market access and/ or lack of alternative income; and (3) relatively weak enforcement of local rules (i.e., low perceptions of risk from sanctions for rule-breaking). These drivers do not stand alone but can act together and add up to impair effective management. We further analyze how enforcement of CBMRM is challenged through a range of institutional; socio-cultural and technical/financial constraints, which are in parts a result of the dynamism and ongoing transformations of management arrangements. Our study underlines the importance of better understanding and contextualizing marine resource management processes under dynamic conditions for an improved understanding of compliance in a particular setting.
- Full Text:
- Date Issued: 2016
Russian wheat aphids: Breakfast, lunch, and supper. Feasting on small grains in South Africa
- Authors: Botha, Christiaan E J , Sacranie, S , Gallagher, Sean , Hill, Jaclyn M
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69031 , vital:29374 , https://doi.org/10.1016/j.sajb.2016.12.006
- Description: The Russian Wheat Aphid (Diuraphis noxia, RWA) negatively impacts commercially grown barley and wheat in South Africa. Climate change, the attendant rise in [CO2], and the appearance of new RWA biotypes have the potential to induce severe crop yield loss in agriculturally important wheat and barley cultivars. This study presents data showing changes in relative aphid population numbers, concurrently with assessments of plant damage under controlled environmental conditions, under ambient and elevated (450 ppm) [CO2]. Extensive structural damage to the vascular tissue and disruption to the transport systems were revealed using light, fluorescence and electron microscopy. This, coupled with biotype population studies, demonstrated that RWA has the capacity to inflict severe, potentially permanent damage to vegetative small grain plants. Furthermore, some currently ‘resistant’ cultivars may well lose resistance as a direct result of increasing atmospheric [CO2]. A small (50 ppm) increase in atmospheric [CO2] may result in increased aphid population numbers, potentially serious plant damage and, by implication, a potentially negative impact on yield, as increased aphid density per plant leads to an accelerated disruption of the assimilate and transpiration transport pathways. These outcomes pose a direct threat to the commercial small grain industry of South Africa and by extension, to other small grain production areas elsewhere.
- Full Text: false
- Date Issued: 2016