Sustainable tourism opportunities for Mauritius
- Authors: Ternel, Maeva
- Date: 2017
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/6118 , vital:21046
- Description: Sustainable Tourism (ST) integrates governance, economic, socio-cultural and environmental dimensions of tourism in tourism development and management. Growing Environmental, Social and Governance (ESG) concerns suggest that traditionally, tourism tends to corrupt the very resources it needs to thrive, and thus its sustainability over the long haul has become of general concern. However, despite the vast and extensive literature dedicated to ST, including preeminent journals providing both a theoretical base and reliable empirical evidence to the subject, the concept of sustainability in tourism remains somehow at its embryonic stage, especially in the case of a small island developing state (SIDS). The research occurred within the context of the destination (Mauritius), with however, a focus on five sizeable Mauritian hotel groups. With tourism being one of the pillars of the Mauritian economy, this research intended to explore the different repercussions of such an industry. The aim of the research was to determine to what extent tourism’s operations and development, was appropriately managed in Mauritius by assessing the country’s current tourism situation relating to sustainability and identifying priority areas for intervention. This, was done using different tools, including the United Nations World Tourism Organisation's framework, the Global Sustainable Tourism Council's guidelines and the Sustainable Tourism Attitude Scale. The contribution this research intended to make was to suggest sustainable tourism opportunities and make recommendations for the tourism sector and its stakeholders for the island of Mauritius. Overall, the research concluded that despite the increased importance of ST, the need for Managed Tourism (MT) and the formulation of general principles and guidelines, tourism governance; poverty reduction; and the sustainability of the natural and cultural environment were identified as areas of particular need and should be considered with high priority for intervention/action.
- Full Text:
- Date Issued: 2017
- Authors: Ternel, Maeva
- Date: 2017
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/6118 , vital:21046
- Description: Sustainable Tourism (ST) integrates governance, economic, socio-cultural and environmental dimensions of tourism in tourism development and management. Growing Environmental, Social and Governance (ESG) concerns suggest that traditionally, tourism tends to corrupt the very resources it needs to thrive, and thus its sustainability over the long haul has become of general concern. However, despite the vast and extensive literature dedicated to ST, including preeminent journals providing both a theoretical base and reliable empirical evidence to the subject, the concept of sustainability in tourism remains somehow at its embryonic stage, especially in the case of a small island developing state (SIDS). The research occurred within the context of the destination (Mauritius), with however, a focus on five sizeable Mauritian hotel groups. With tourism being one of the pillars of the Mauritian economy, this research intended to explore the different repercussions of such an industry. The aim of the research was to determine to what extent tourism’s operations and development, was appropriately managed in Mauritius by assessing the country’s current tourism situation relating to sustainability and identifying priority areas for intervention. This, was done using different tools, including the United Nations World Tourism Organisation's framework, the Global Sustainable Tourism Council's guidelines and the Sustainable Tourism Attitude Scale. The contribution this research intended to make was to suggest sustainable tourism opportunities and make recommendations for the tourism sector and its stakeholders for the island of Mauritius. Overall, the research concluded that despite the increased importance of ST, the need for Managed Tourism (MT) and the formulation of general principles and guidelines, tourism governance; poverty reduction; and the sustainability of the natural and cultural environment were identified as areas of particular need and should be considered with high priority for intervention/action.
- Full Text:
- Date Issued: 2017
Synthesis and bioassay of rationally designed DXR inhibitors as potential antimalarial lead compounds
- Authors: Nokalipa, Iviwe Cwaita
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4888 , vital:20740
- Description: Globally, the eradication of malaria has been challenging due to the problem of resistance that past and currently available drugs exhibit. This is exacerbated by the inherent need for anti-malarial drugs to be affordable to the poverty-stricken majority that is primarily affected by this burden. This research has focused on the development of potential inhibitors of 1-deoxy-D- xylulose-5 phosphate reductoisomerase (DXR), an essential enzyme in the mevalonate- independent pathway for the biosynthesis of isoprenoids in Plasmodium falciparum. DXR mediates the isomerisation and reduction of 1-deoxy-D-xylulose-5-phosphate into 2-C- methyl-D-erithrytol 4-phosphate. This enzyme has been determined to be a target for the development of novel antimalarial agents and extensive molecular modelling has been undertaken to develop inhibitors that fit into the DXR active site. The in silico docking data have been used to inform the design and synthesis of various N-benzyl-substituted phosphoramidate ligands that were determined to have potential as novel substrate mimics of fosmidomycin, a known DXR inhibitor. Synthesis of the N-benzyl-substituted phosphoramidate ligands involved a nine-step sequence commencing from diethyl phosphoramidate. In all, some 40 compounds have been prepared, some of them new, and were fully characterized using NMR. Attention has also been given to the mass spectrometric fragmentation patterns exhibited by selected intermediates. Four of the final products were evaluated for in vitro antimalarial activity using a PLDH assay and exhibited IC50 values < 100 µM.
- Full Text:
- Date Issued: 2017
- Authors: Nokalipa, Iviwe Cwaita
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4888 , vital:20740
- Description: Globally, the eradication of malaria has been challenging due to the problem of resistance that past and currently available drugs exhibit. This is exacerbated by the inherent need for anti-malarial drugs to be affordable to the poverty-stricken majority that is primarily affected by this burden. This research has focused on the development of potential inhibitors of 1-deoxy-D- xylulose-5 phosphate reductoisomerase (DXR), an essential enzyme in the mevalonate- independent pathway for the biosynthesis of isoprenoids in Plasmodium falciparum. DXR mediates the isomerisation and reduction of 1-deoxy-D-xylulose-5-phosphate into 2-C- methyl-D-erithrytol 4-phosphate. This enzyme has been determined to be a target for the development of novel antimalarial agents and extensive molecular modelling has been undertaken to develop inhibitors that fit into the DXR active site. The in silico docking data have been used to inform the design and synthesis of various N-benzyl-substituted phosphoramidate ligands that were determined to have potential as novel substrate mimics of fosmidomycin, a known DXR inhibitor. Synthesis of the N-benzyl-substituted phosphoramidate ligands involved a nine-step sequence commencing from diethyl phosphoramidate. In all, some 40 compounds have been prepared, some of them new, and were fully characterized using NMR. Attention has also been given to the mass spectrometric fragmentation patterns exhibited by selected intermediates. Four of the final products were evaluated for in vitro antimalarial activity using a PLDH assay and exhibited IC50 values < 100 µM.
- Full Text:
- Date Issued: 2017
Synthesis and evaluation of arylpyrrole-chalcone hybrids as antiplasmodial and antitrypanosomal agents
- Authors: Zulu, Ayanda Ignatia
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65268 , vital:28716
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
- Authors: Zulu, Ayanda Ignatia
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65268 , vital:28716
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
Synthesis and photophysical studies of crown ether-bodipy dyes and the fabrication of bodipy embedded fluorescent nanofibers
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
- Full Text:
- Date Issued: 2017
- Authors: Stone, Justin
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4953 , vital:20746
- Description: This study has three major objectives: 1) to synthesize a series of structurally related BODIPY dyes, 2) to fabricate BODIPY embedded electrospun nanofibers, and 3) to investigate and characterize the photophysical properties of all synthesized BODIPY dyes with a special focus on their ability to generate singlet oxygen. This thesis first explores the acid catalysed condensation reaction to produce two structurally analogous meso-substituted BODIPY dyes based on cuminaldehyde and 4-dimethylaminobenzaldehdye. In order to enhance the rate of ISC and promote the generation of reactive oxygen species bromine atoms were then attached to the BODIPY 2,6-positions. These BODIPY dyes were then embedded in a polystyrene solution and electrospun into nanofibers. The resulting nanofibers were found to be highly fluorescent, but were no longer able to generate singlet oxygen. Ion-sensitive BODIPYs were prepared from the dibrominated BODIPY dyes by employing a modified Knoevenagel condensation reaction to form a styryl bond with 4’-formylbenzo-15-crown-5 at the 3,5-position of the BODIPY core. Changes in the morphology and position of the absorption and emission spectra of these crown ether-styryl BODIPY dyes were observed in the presence of sodium ions. These results imply that crown ether-substituted BODIPY dyes could function as ion sensors.
- Full Text:
- Date Issued: 2017
Synthesis and physicochemical evaluation of a series of boron dipyrromethene dye derivatives for potential utility in antimicrobial photodynamic therapy and nonlinear optics
- Authors: Kubheka, Gugu Patience
- Date: 2017
- Subjects: Dyes and dyeing -- Chemistry , Photochemotherapy , Cancer -- Photochemotherapy , Anti-infective agents , Nonlinear optics , BODIPY
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4776 , vital:20723
- Description: A series of new BODIPY dye derivatives have been synthesized and characterized using various characterization tools such as 1H-NMR, MALDI-TOF mass spectrometry, FT-IR, UV-visible spectrophotometry and elemental analysis. The aniline-substituted BODIPY derivative was further coordinated with gold nanorods and the characterization was achieved by transmission electron microscopy (TEM), X-ray diffractometry (XRD) and X-ray photoelectron spectroscopy (XPS).In addition to this dye, quaternized BODIPY dyes were also synthesized and investigated for their potential utility as photosentitizers in antimicrobial photodynamic therapy (APDT).BODIPY dyes with pyrene substituted styryl groups were embedded in polymer thin film using poly(bisphenol A carbonate) (PBC) to study their optical limiting properties. The optical limiting values of these BODIPY dyes once embedded in thin films were found to be greatly improved and the limiting intensityof each film was well below the maximum threshold which is set to be 0.95 J.cm-². The physicochemical properties and NLO parameters of all of the synthesized dyes were investigated.
- Full Text:
- Date Issued: 2017
- Authors: Kubheka, Gugu Patience
- Date: 2017
- Subjects: Dyes and dyeing -- Chemistry , Photochemotherapy , Cancer -- Photochemotherapy , Anti-infective agents , Nonlinear optics , BODIPY
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4776 , vital:20723
- Description: A series of new BODIPY dye derivatives have been synthesized and characterized using various characterization tools such as 1H-NMR, MALDI-TOF mass spectrometry, FT-IR, UV-visible spectrophotometry and elemental analysis. The aniline-substituted BODIPY derivative was further coordinated with gold nanorods and the characterization was achieved by transmission electron microscopy (TEM), X-ray diffractometry (XRD) and X-ray photoelectron spectroscopy (XPS).In addition to this dye, quaternized BODIPY dyes were also synthesized and investigated for their potential utility as photosentitizers in antimicrobial photodynamic therapy (APDT).BODIPY dyes with pyrene substituted styryl groups were embedded in polymer thin film using poly(bisphenol A carbonate) (PBC) to study their optical limiting properties. The optical limiting values of these BODIPY dyes once embedded in thin films were found to be greatly improved and the limiting intensityof each film was well below the maximum threshold which is set to be 0.95 J.cm-². The physicochemical properties and NLO parameters of all of the synthesized dyes were investigated.
- Full Text:
- Date Issued: 2017
Synthesis, characterisation and evaluation of novel ferrocene-thiazole derivatives as antiplasmodial agents
- Authors: Hakizimana, Emmanuel Victor
- Date: 2017
- Subjects: Plasmodium , Malaria -- Chemotherapy , Plasmodium falciparum , Plasmodium -- Inhibitors , Drug resistance in microorganisms , Thiaszoles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/5304 , vital:20807
- Description: Malaria is mosquito-transmitted disease which continues to pose threat to humanity, despite the efforts undertaken by the scientific community, government entities and international organizations. The major problem is that Plasmodium species have developed resistance against available drugs. In order to counter this problem, antimalarial drugs that are efficacious and with novel mode of action are of great necessity. Thiazole derivatives, in particular aminomethylthiazole analogues, have been shown to exhibit promising antimalarial activity against Plasmodium falciparum strains. Previous studies reported the hit compound MMV010539, which showed good antimalarial activity against both K1 (CQ and multidrug resistant strains) and NF54 (CQ sensitive strain). In this study, MMV010539 was deemed to be as an attractive compound to generate novel analogues by addition of ferrocenyl organometallic unit. The ferrocene based compounds have shown biological activity; and with ferroquine currently in clinical trials there has been increasing research into identifying new ferrocenyl-containing molecules as potential antimalarial agents. Herein, thiazole ferrocene based molecules 3.22a-e were synthesised in low to good yields. Their structural identities were confirmed using conventional spectroscopic techniques (¹H and ¹³C NMR, FT-IR spectroscopy and mass spectrometry). The cell cytotoxicity assay of all final compounds confirmed that all ferrocene-thiazole blends 3.22a-e were non-toxic against HeLa cell lines. However, the in vitro biological assay revealed that despite the absence of cell cytotoxicity these compounds poorly inhibited the growth of Plasmodium falciparum parasite. As the aim was to expand further the structure-activity relationship (SAR) of MMV010539, this study confirmed the previous findings that there is a limited structural modification that could be accommodated as indicated in Figure 3.3 (Panel C). Moreover, the combination of ferrocenyl moiety and various alkylamines resulted in compounds with poor antiplasmodial potency, further suggesting that the free amine (Panel A, Figure 3.3) is important for activity.
- Full Text:
- Date Issued: 2017
- Authors: Hakizimana, Emmanuel Victor
- Date: 2017
- Subjects: Plasmodium , Malaria -- Chemotherapy , Plasmodium falciparum , Plasmodium -- Inhibitors , Drug resistance in microorganisms , Thiaszoles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/5304 , vital:20807
- Description: Malaria is mosquito-transmitted disease which continues to pose threat to humanity, despite the efforts undertaken by the scientific community, government entities and international organizations. The major problem is that Plasmodium species have developed resistance against available drugs. In order to counter this problem, antimalarial drugs that are efficacious and with novel mode of action are of great necessity. Thiazole derivatives, in particular aminomethylthiazole analogues, have been shown to exhibit promising antimalarial activity against Plasmodium falciparum strains. Previous studies reported the hit compound MMV010539, which showed good antimalarial activity against both K1 (CQ and multidrug resistant strains) and NF54 (CQ sensitive strain). In this study, MMV010539 was deemed to be as an attractive compound to generate novel analogues by addition of ferrocenyl organometallic unit. The ferrocene based compounds have shown biological activity; and with ferroquine currently in clinical trials there has been increasing research into identifying new ferrocenyl-containing molecules as potential antimalarial agents. Herein, thiazole ferrocene based molecules 3.22a-e were synthesised in low to good yields. Their structural identities were confirmed using conventional spectroscopic techniques (¹H and ¹³C NMR, FT-IR spectroscopy and mass spectrometry). The cell cytotoxicity assay of all final compounds confirmed that all ferrocene-thiazole blends 3.22a-e were non-toxic against HeLa cell lines. However, the in vitro biological assay revealed that despite the absence of cell cytotoxicity these compounds poorly inhibited the growth of Plasmodium falciparum parasite. As the aim was to expand further the structure-activity relationship (SAR) of MMV010539, this study confirmed the previous findings that there is a limited structural modification that could be accommodated as indicated in Figure 3.3 (Panel C). Moreover, the combination of ferrocenyl moiety and various alkylamines resulted in compounds with poor antiplasmodial potency, further suggesting that the free amine (Panel A, Figure 3.3) is important for activity.
- Full Text:
- Date Issued: 2017
Synthesis, characterisation and evaluation of novel ferrocene-thiazole derivatives as antiplasmodial agents
- Authors: Hakizimana, Emmanuel Victor
- Date: 2017
- Subjects: Plasmodium , Malaria -- Chemotherapy , Plasmodium falciparum , Plasmodium -- Inhibitors , Drug resistance in microorganisms , Thiaszoles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/96068 , vital:31232
- Description: Malaria is mosquito-transmitted disease which continues to pose threat to humanity, despite the efforts undertaken by the scientific community, government entities and international organizations. The major problem is that Plasmodium species have developed resistance against available drugs. In order to counter this problem, antimalarial drugs that are efficacious and with novel mode of action are of great necessity. Thiazole derivatives, in particular aminomethylthiazole analogues, have been shown to exhibit promising antimalarial activity against Plasmodium falciparum strains. Previous studies reported the hit compound MMV010539, which showed good antimalarial activity against both K1 (CQ and multidrug resistant strains) and NF54 (CQ sensitive strain). In this study, MMV010539 was deemed to be as an attractive compound to generate novel analogues by addition of ferrocenyl organometallic unit. The ferrocene based compounds have shown biological activity; and with ferroquine currently in clinical trials there has been increasing research into identifying new ferrocenyl-containing molecules as potential antimalarial agents. Herein, thiazole ferrocene based molecules 3.22a-e were synthesised in low to good yields. Their structural identities were confirmed using conventional spectroscopic techniques (¹H and ¹³C NMR, FT-IR spectroscopy and mass spectrometry). The cell cytotoxicity assay of all final compounds confirmed that all ferrocene-thiazole blends 3.22a-e were non-toxic against HeLa cell lines. However, the in vitro biological assay revealed that despite the absence of cell cytotoxicity these compounds poorly inhibited the growth of Plasmodium falciparum parasite. As the aim was to expand further the structure-activity relationship (SAR) of MMV010539, this study confirmed the previous findings that there is a limited structural modification that could be accommodated as indicated in Figure 3.3 (Panel C). Moreover, the combination of ferrocenyl moiety and various alkylamines resulted in compounds with poor antiplasmodial potency, further suggesting that the free amine (Panel A, Figure 3.3) is important for activity.
- Full Text:
- Date Issued: 2017
- Authors: Hakizimana, Emmanuel Victor
- Date: 2017
- Subjects: Plasmodium , Malaria -- Chemotherapy , Plasmodium falciparum , Plasmodium -- Inhibitors , Drug resistance in microorganisms , Thiaszoles
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/96068 , vital:31232
- Description: Malaria is mosquito-transmitted disease which continues to pose threat to humanity, despite the efforts undertaken by the scientific community, government entities and international organizations. The major problem is that Plasmodium species have developed resistance against available drugs. In order to counter this problem, antimalarial drugs that are efficacious and with novel mode of action are of great necessity. Thiazole derivatives, in particular aminomethylthiazole analogues, have been shown to exhibit promising antimalarial activity against Plasmodium falciparum strains. Previous studies reported the hit compound MMV010539, which showed good antimalarial activity against both K1 (CQ and multidrug resistant strains) and NF54 (CQ sensitive strain). In this study, MMV010539 was deemed to be as an attractive compound to generate novel analogues by addition of ferrocenyl organometallic unit. The ferrocene based compounds have shown biological activity; and with ferroquine currently in clinical trials there has been increasing research into identifying new ferrocenyl-containing molecules as potential antimalarial agents. Herein, thiazole ferrocene based molecules 3.22a-e were synthesised in low to good yields. Their structural identities were confirmed using conventional spectroscopic techniques (¹H and ¹³C NMR, FT-IR spectroscopy and mass spectrometry). The cell cytotoxicity assay of all final compounds confirmed that all ferrocene-thiazole blends 3.22a-e were non-toxic against HeLa cell lines. However, the in vitro biological assay revealed that despite the absence of cell cytotoxicity these compounds poorly inhibited the growth of Plasmodium falciparum parasite. As the aim was to expand further the structure-activity relationship (SAR) of MMV010539, this study confirmed the previous findings that there is a limited structural modification that could be accommodated as indicated in Figure 3.3 (Panel C). Moreover, the combination of ferrocenyl moiety and various alkylamines resulted in compounds with poor antiplasmodial potency, further suggesting that the free amine (Panel A, Figure 3.3) is important for activity.
- Full Text:
- Date Issued: 2017
Taste masking of clarithromycin with ion exchange resins
- Authors: Ntemi, Pascal Vitalis
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65178 , vital:28701
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
- Authors: Ntemi, Pascal Vitalis
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65178 , vital:28701
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
Teachers’ use of situated learning approaches to teach environmental topics in Natural Science and Health Education: a multi-case study of two Namibian teachers
- Authors: Mamili, Joy Z
- Date: 2017
- Subjects: Environmental education -- Namibia , Science -- Study and teaching -- Namibia -- Cast studies , Health education -- Namibia -- Case studies
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/40901 , vital:25037
- Description: This study focuses on the use of situated learning approaches in the teaching of environmental topics in Natural Science and Health Education (NSHED) and is the first of its kind in Namibia. Although situated learning approaches, as examples of learner-centred pedagogy, are advocated in national education policies, little empirical research has been conducted in Namibia into how situated learning approaches play out in classroom practice. Therefore, the goal of this study was to find out how NSHED teachers use situated learning approaches when teaching environmental topics. The study reviews the characteristics of situated learning theory and clarifies situated learning approaches as a form of learner-centred pedagogy which is actively promoted in the Namibian schooling system. The study commences with a contextual profile of the communities around the two selected schools. This describes the socio-economic and social-ecological context in which learners are taught about environmental topics. The profile also describes the under-performance of the schools in recent national assessments, especially in relation to environmental topics in NSHED. Drawing on data generated through document analysis, semi-structured interviews and classroom observations, the study concluded that: 1. NSHED teachers both knew about and wished to create an authentic context to enhance situated learning approaches. However, their understandings and applications of situated learning tended to be basic. 2. Teachers dominated the scaffolding process and their scaffolding strategies did not enable learners to increase independence in performing. 3. Despite the use of situated learning approaches, learners’ engagement with lesson content was superficial, and the teachers did little to encourage deeper reflections or critical thinking. 4. The teachers appeared to use situated learning approaches to clarify subject content but not to encourage broader environmental understanding, action-taking and change. Based on the research findings, the study recommends that situated learning approaches be integrated into pre- and in-service teacher training with the aim of enhancing teachers’ understanding regarding the use of situated learning approaches in the teaching of environmental topics in NSHED.
- Full Text:
- Date Issued: 2017
- Authors: Mamili, Joy Z
- Date: 2017
- Subjects: Environmental education -- Namibia , Science -- Study and teaching -- Namibia -- Cast studies , Health education -- Namibia -- Case studies
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/40901 , vital:25037
- Description: This study focuses on the use of situated learning approaches in the teaching of environmental topics in Natural Science and Health Education (NSHED) and is the first of its kind in Namibia. Although situated learning approaches, as examples of learner-centred pedagogy, are advocated in national education policies, little empirical research has been conducted in Namibia into how situated learning approaches play out in classroom practice. Therefore, the goal of this study was to find out how NSHED teachers use situated learning approaches when teaching environmental topics. The study reviews the characteristics of situated learning theory and clarifies situated learning approaches as a form of learner-centred pedagogy which is actively promoted in the Namibian schooling system. The study commences with a contextual profile of the communities around the two selected schools. This describes the socio-economic and social-ecological context in which learners are taught about environmental topics. The profile also describes the under-performance of the schools in recent national assessments, especially in relation to environmental topics in NSHED. Drawing on data generated through document analysis, semi-structured interviews and classroom observations, the study concluded that: 1. NSHED teachers both knew about and wished to create an authentic context to enhance situated learning approaches. However, their understandings and applications of situated learning tended to be basic. 2. Teachers dominated the scaffolding process and their scaffolding strategies did not enable learners to increase independence in performing. 3. Despite the use of situated learning approaches, learners’ engagement with lesson content was superficial, and the teachers did little to encourage deeper reflections or critical thinking. 4. The teachers appeared to use situated learning approaches to clarify subject content but not to encourage broader environmental understanding, action-taking and change. Based on the research findings, the study recommends that situated learning approaches be integrated into pre- and in-service teacher training with the aim of enhancing teachers’ understanding regarding the use of situated learning approaches in the teaching of environmental topics in NSHED.
- Full Text:
- Date Issued: 2017
The clinical utility of the Kinetic School Drawing (KSD)
- Authors: Mohammed, Raghshanda
- Date: 2017
- Subjects: Kinetic Family Drawing Test , Art therapy for children , Kinetic-House-Tree-Person Technique , Children's drawings -- Psychological aspects , Projective techniques for children , Psychological tests for children
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/4433 , vital:20669
- Description: This study aimed to establish the clinical utility of the Kinetic School Drawing (KSD) projective technique. It attempted to do so by using an existing self-report measure of children’s self-perceptions in the school environment (Harter’s Self-Perception Profile for Children) by which to corroborate the projections derived from the KSD’s. Following the development of this measure (in 1984) limited research has been undertaken to assess its validity, reliability and clinical utility despite promising initial findings. The KSD has therefore not received much attention and as a result, it has yet to be established as a useful psychological assessment tool. This study sought to revive interest and discussion around the KSD. Qualitative methods and specifically thematic analysis was employed to explore the usefulness of the KSD in an attempt to address the gap in the literature in a meaningful way. The sample consisted of 26 grade 5 learners from a private school in the Eastern Cape. The themes were presented under the following headings: scholastic competence, athletic competence, social competence, physical appearance and behavioural conduct.
- Full Text:
- Date Issued: 2017
- Authors: Mohammed, Raghshanda
- Date: 2017
- Subjects: Kinetic Family Drawing Test , Art therapy for children , Kinetic-House-Tree-Person Technique , Children's drawings -- Psychological aspects , Projective techniques for children , Psychological tests for children
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/4433 , vital:20669
- Description: This study aimed to establish the clinical utility of the Kinetic School Drawing (KSD) projective technique. It attempted to do so by using an existing self-report measure of children’s self-perceptions in the school environment (Harter’s Self-Perception Profile for Children) by which to corroborate the projections derived from the KSD’s. Following the development of this measure (in 1984) limited research has been undertaken to assess its validity, reliability and clinical utility despite promising initial findings. The KSD has therefore not received much attention and as a result, it has yet to be established as a useful psychological assessment tool. This study sought to revive interest and discussion around the KSD. Qualitative methods and specifically thematic analysis was employed to explore the usefulness of the KSD in an attempt to address the gap in the literature in a meaningful way. The sample consisted of 26 grade 5 learners from a private school in the Eastern Cape. The themes were presented under the following headings: scholastic competence, athletic competence, social competence, physical appearance and behavioural conduct.
- Full Text:
- Date Issued: 2017
The deductibility of damages and associated legal expenses for the purposes of determining taxable income in South Africa
- Authors: Madovi, Ezekiel
- Date: 2017
- Subjects: Income tax -- Law and legislation -- South Africa , Damages -- Taxation -- South Africa , South Africa. Income Tax Act, 1962
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4344 , vital:20650
- Description: The deduction of damages and the associated legal costs must satisfy the requirements of the preamble to section 11 and section 11(a) of the Income Tax Act 58 of 1962, read with section 23(g) (referred to as the general deduction formula). This research examined under what circumstances a payer of damages and the associated legal costs would be able to claim a deduction from taxable income. This research also considered whether or not the issue of fault is a relevant consideration in determining whether a deduction should be allowed. In some cases the courts appear to have disallowed a deduction if the expenditure or loss was incurred as a result of a negligent or unlawful act. In other instances the courts have allowed the deduction of damages despite the expenditure or loss having been incurred as a result of a negligent or unlawful act. The research concludes that negligence is not a relevant consideration in the deduction of damages and the associated legal costs. In order to secure a claim for damages the taxpayer must prove that the expenditure was incurred in the production of income and it was expended for the purposes of trade. Associated legal costs are only deductible if the damages satisfy the requirements of section 11(c).
- Full Text:
- Date Issued: 2017
- Authors: Madovi, Ezekiel
- Date: 2017
- Subjects: Income tax -- Law and legislation -- South Africa , Damages -- Taxation -- South Africa , South Africa. Income Tax Act, 1962
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/4344 , vital:20650
- Description: The deduction of damages and the associated legal costs must satisfy the requirements of the preamble to section 11 and section 11(a) of the Income Tax Act 58 of 1962, read with section 23(g) (referred to as the general deduction formula). This research examined under what circumstances a payer of damages and the associated legal costs would be able to claim a deduction from taxable income. This research also considered whether or not the issue of fault is a relevant consideration in determining whether a deduction should be allowed. In some cases the courts appear to have disallowed a deduction if the expenditure or loss was incurred as a result of a negligent or unlawful act. In other instances the courts have allowed the deduction of damages despite the expenditure or loss having been incurred as a result of a negligent or unlawful act. The research concludes that negligence is not a relevant consideration in the deduction of damages and the associated legal costs. In order to secure a claim for damages the taxpayer must prove that the expenditure was incurred in the production of income and it was expended for the purposes of trade. Associated legal costs are only deductible if the damages satisfy the requirements of section 11(c).
- Full Text:
- Date Issued: 2017
The determinants of credit default swap spreads in emerging market economies
- Authors: Matakane, Lwazi
- Date: 2017
- Subjects: Bank loans -- BRIC countries , Risk management -- BRIC countries , Swaps (Finance) -- BRIC countries , BRIC countries -- Economic conditions , Rating agencies (Finance)
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/7142 , vital:21221
- Description: Emerging markets have become a destination for international portfolio flows as a result of global financial integration. This has allowed exogenous factors like sentiment and developed country monetary policy to affect developing countries capital markets and macroeconomic fundamentals. This study analyses the impact of investor sentiment alongside US monetary policy, country specific risks, inflation and domestic stock returns on the BRICS credit default spreads. To investigate this relationship, the study uses panel data and a fixed effects model. The results of the panel regressions suggest that all variables had an impact on the variation of BRICS credit default spreads however the crisis may have distorted the relationship among the variables. Sovereign ratings had an inverse relationship depicting a rise in ratings decreasing the credit default premium. This was in line with a priori expectations. Domestic company earnings also had an inverse relationship with BRCIS credit default premia, the magnitude of which is dependent on the value of the index. This is to say the higher the index, the more significant the effect on the BRICS default premium. US monetary policy was significant and in line with expectations of a linear relationship between emerging market credit default spreads when controlling for the crisis. In the crisis period however, results depicted an inverse relationship going against a priori expectations. The inflation variable was found to have a greater impact on CDS spreads during the crisis period, while the VIX index had a linear relationship with the default premia albeit the impact was not highly significant. The study concludes that the financial crisis was an important event that affected the relationship of these variables with BRICS country default spreads and had read through to market participant’s behaviour at the time.
- Full Text:
- Date Issued: 2017
- Authors: Matakane, Lwazi
- Date: 2017
- Subjects: Bank loans -- BRIC countries , Risk management -- BRIC countries , Swaps (Finance) -- BRIC countries , BRIC countries -- Economic conditions , Rating agencies (Finance)
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/7142 , vital:21221
- Description: Emerging markets have become a destination for international portfolio flows as a result of global financial integration. This has allowed exogenous factors like sentiment and developed country monetary policy to affect developing countries capital markets and macroeconomic fundamentals. This study analyses the impact of investor sentiment alongside US monetary policy, country specific risks, inflation and domestic stock returns on the BRICS credit default spreads. To investigate this relationship, the study uses panel data and a fixed effects model. The results of the panel regressions suggest that all variables had an impact on the variation of BRICS credit default spreads however the crisis may have distorted the relationship among the variables. Sovereign ratings had an inverse relationship depicting a rise in ratings decreasing the credit default premium. This was in line with a priori expectations. Domestic company earnings also had an inverse relationship with BRCIS credit default premia, the magnitude of which is dependent on the value of the index. This is to say the higher the index, the more significant the effect on the BRICS default premium. US monetary policy was significant and in line with expectations of a linear relationship between emerging market credit default spreads when controlling for the crisis. In the crisis period however, results depicted an inverse relationship going against a priori expectations. The inflation variable was found to have a greater impact on CDS spreads during the crisis period, while the VIX index had a linear relationship with the default premia albeit the impact was not highly significant. The study concludes that the financial crisis was an important event that affected the relationship of these variables with BRICS country default spreads and had read through to market participant’s behaviour at the time.
- Full Text:
- Date Issued: 2017
The development and institutionalisation of knowledge and knowledge-sharing practices relating to the management of healthcare risk waste in a home-based care setting
- Authors: Masilela, Mapula Priscilla
- Date: 2017
- Subjects: Medical wastes -- Management -- South Africa -- West Rand , Medical wastes -- Government policy -- South Africa -- West Rand , Environmental health -- South Africa -- West Rand , Environmental health -- Administration -- South Africa -- West Rand , Environmental health -- Government policy -- South Africa -- West Rand
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/13142 , vital:21807
- Description: Improperly managed healthcare risk waste is associated with environmental degradation due to its potential to pollute air, land and water; it also poses a public health threat due to risks to community members (adults and children) who may find themselves exposed to waste that has been disposed of improperly. Despite these obvious environmental health risks, there is little information or legislative guidance on how to effectively manage the healthcare risk waste generated by community health workers who move from house to house and do not operate out of a fixed clinic with formal waste management facilities. This poses a challenge for municipal environmental health practitioners who are mandated to ensure compliance and to monitor the management of healthcare risk waste by community home-based care facilities. This educational study looks at how the knowledge held by environmental health practitioners influences knowledge-sharing practices and management of healthcare risk waste by community health workers, and how these knowledge-sharing practices can be developed and institutionalised. The study takes an interventionist approach within the social constructionist tradition. Cultural- Historical Activity Theory (CHAT) and expansive learning provide the theoretical and methodological framework to surface systemic tensions and contradictions affecting knowledgesharing and healthcare risk waste management practices. A series of Change Laboratory Workshops using the Developmental Work Research methodology enabled a twenty-seven month expansive learning process with selected municipal employees and community health workers in a small South African city. The study found that employees (such as environmental health practitioners and waste inspectors) working in municipal activity systems knew very little about the forms and functions of community home-based care facilities in their municipality. As such, their knowledge-sharing practices about the management of healthcare risk waste were restricted and generally unsystematic, which in turn contributed to inappropriate and often haphazard healthcare risk waste management practices by community health workers. As an interventionist project, the study concluded that the participatory, expansive learning process it initiated had built knowledge-sharing networks, enabled professional boundary crossing and potentially institutionalised better knowledge-sharing practices relevant to the effective management of healthcare risk waste.
- Full Text:
- Date Issued: 2017
- Authors: Masilela, Mapula Priscilla
- Date: 2017
- Subjects: Medical wastes -- Management -- South Africa -- West Rand , Medical wastes -- Government policy -- South Africa -- West Rand , Environmental health -- South Africa -- West Rand , Environmental health -- Administration -- South Africa -- West Rand , Environmental health -- Government policy -- South Africa -- West Rand
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/13142 , vital:21807
- Description: Improperly managed healthcare risk waste is associated with environmental degradation due to its potential to pollute air, land and water; it also poses a public health threat due to risks to community members (adults and children) who may find themselves exposed to waste that has been disposed of improperly. Despite these obvious environmental health risks, there is little information or legislative guidance on how to effectively manage the healthcare risk waste generated by community health workers who move from house to house and do not operate out of a fixed clinic with formal waste management facilities. This poses a challenge for municipal environmental health practitioners who are mandated to ensure compliance and to monitor the management of healthcare risk waste by community home-based care facilities. This educational study looks at how the knowledge held by environmental health practitioners influences knowledge-sharing practices and management of healthcare risk waste by community health workers, and how these knowledge-sharing practices can be developed and institutionalised. The study takes an interventionist approach within the social constructionist tradition. Cultural- Historical Activity Theory (CHAT) and expansive learning provide the theoretical and methodological framework to surface systemic tensions and contradictions affecting knowledgesharing and healthcare risk waste management practices. A series of Change Laboratory Workshops using the Developmental Work Research methodology enabled a twenty-seven month expansive learning process with selected municipal employees and community health workers in a small South African city. The study found that employees (such as environmental health practitioners and waste inspectors) working in municipal activity systems knew very little about the forms and functions of community home-based care facilities in their municipality. As such, their knowledge-sharing practices about the management of healthcare risk waste were restricted and generally unsystematic, which in turn contributed to inappropriate and often haphazard healthcare risk waste management practices by community health workers. As an interventionist project, the study concluded that the participatory, expansive learning process it initiated had built knowledge-sharing networks, enabled professional boundary crossing and potentially institutionalised better knowledge-sharing practices relevant to the effective management of healthcare risk waste.
- Full Text:
- Date Issued: 2017
The development of biodegradable aerogel scaffolds for the generation of vascularised 3D adipose tissue models
- Authors: Makhene, Lebohang
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/59245 , vital:27492
- Description: Expected release date-April 2019
- Full Text:
- Date Issued: 2017
- Authors: Makhene, Lebohang
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/59245 , vital:27492
- Description: Expected release date-April 2019
- Full Text:
- Date Issued: 2017
The development of techniques for the identification of novel viruses associated with acute infantile gastroenteritis in South Africa
- Authors: Jaquet, Brittany J
- Date: 2017
- Subjects: Gastroenteritis in children -- Treatment , Gastroenteritis in children -- Treatment -- South Africa , Antiviral agents , Viral vaccines , Rotaviruses , Virus diseases in children
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/38013 , vital:24725
- Description: Gastroenteritis is a serious disease affecting both children and adults globally, but is more predominant in children with over half a million deaths reported each year. The leading cause of this disease is rotavirus, which accounts for 38% of all hospitalised cases. There has, however, been a significant decrease in the number of deaths associated with rotavirus worldwide since the introduction of the two vaccines, Rotarix® and RotaTeq®. A large number of cases are therefore either associated with other viruses, such as norovirus, Aichi virus (AiV) or Saffold virus (SAFV), or are of unknown aetiology. This study thus aims to develop techniques for the identification of viruses associated with gastroenteritis. Theiler’s murine encephalomyelitis virus (TMEV) was used to develop the sample preparation, transmission electron microscopy and RT-PCR techniques used in this study. This virus was chosen as a replication system using baby hamster kidney cells can be used to create high concentrations of viral particles from which RNA can be extracted preventing the waste of the limited samples. The virus particles are also similar in size and morphology to the viruses to be identified in this study, as it belongs to the same family. After sample preparation, TEM analysis showed the presence of small, round, non-enveloped virus particles in the TMEV sample. Due to the low concentration of virus particles, PEG precipitation was performed using both 0.15 M and 0.25 M NaCl and 8% (w/v) PEG 6000. TEM analysis then showed an increase in viral particle concentration, with the highest concentration observed at 0.25 M NaCl and 8% PEG 6000. RNA was successfully extracted and RT-PCR assays were performed for both the VP1 and 2B coding regions of TMEV. A method for creating a positive control for the RT-PCR assay was developed by the in vitro transcription of RNA from pTMEV, which contains the cDNA of TMEV. The RNA was then used as the template for the 2B two-step RT-PCR assay. A product of 412 bp was successfully amplified from the in vitro transcribed RNA and the sensitivity of the RT-PCR assay was determined. Using a Norovirus GII positive stool sample provided by Maureen Taylor, a nested RT-PCR assay was developed for the NoV GII N/S domain using a previously-published primer set and cycling parameters. A 342 bp product was successfully amplified from the RNA extracted from the stool sample and cloned into pGEM®-T Easy to produce pNoVGII. Using the plasmid containing the AiV 5’UTR and the PCR amplicon for AiV 3CD, RT-PCR assays were developed for AiV 5’UTR and partial 3CD. The RT-PCR assays produced a 1008 bp product for AiV 5’UTR and 266 bp for AiV 3CD, which were cloned into pGEM®-T Easy to produce pAiV5’UTR and pAiV3CD, respectively. Using in vitro transcribed RNA from pNoVGII, pAiV5’UTR, pAiV3CD and pSAFV, which contains the SAFV cDNA, positive controls were developed for the RT-PCR assays for NoV GII, AiV 5’UTR, AiV 3CD and SAFV 2C. The sensitivity of these assays was determined. The samples chosen for this study include wastewater collected from the Belmont Valley water treatment plant, oysters suspected to be infected with viruses collected from Port Elizabeth, South Africa and 30 stool samples from symptomatic patients. With the methods developed using TMEV, the wastewater, oysters and 30 stool samples were filter-sterilised, concentrated and screened by TEM. All samples showed the presence of virus particles. RNA was successfully extracted and the wastewater, oyster and 30 stool samples were screened for NoV GII using the NoV GII RT-PCR assay. The wastewater, oysters and 11 of the stool samples produced the 342 bp NoV GII PCR product and BLAST analysis determined the nucleotide sequences to be NoV GII.4. This shows that this study was able to develop sample preparation techniques and TEM analysis for selected samples and RT-PCR assays for NoV GII, AiV and SAFV. The NoV GII RT-PCR assay was successfully used for the screening of the wastewater, oysters and 30 stool samples for NoV GII. Due to the high number of gastroenteritis cases with unknown aetiology in South Africa, the development of techniques for the identification of NoV, AiV, SAFV and other viruses is very important. The identification of these viruses will allow for better surveillance, treatment and prevention of gastroenteritis in South Africa.
- Full Text:
- Date Issued: 2017
- Authors: Jaquet, Brittany J
- Date: 2017
- Subjects: Gastroenteritis in children -- Treatment , Gastroenteritis in children -- Treatment -- South Africa , Antiviral agents , Viral vaccines , Rotaviruses , Virus diseases in children
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/38013 , vital:24725
- Description: Gastroenteritis is a serious disease affecting both children and adults globally, but is more predominant in children with over half a million deaths reported each year. The leading cause of this disease is rotavirus, which accounts for 38% of all hospitalised cases. There has, however, been a significant decrease in the number of deaths associated with rotavirus worldwide since the introduction of the two vaccines, Rotarix® and RotaTeq®. A large number of cases are therefore either associated with other viruses, such as norovirus, Aichi virus (AiV) or Saffold virus (SAFV), or are of unknown aetiology. This study thus aims to develop techniques for the identification of viruses associated with gastroenteritis. Theiler’s murine encephalomyelitis virus (TMEV) was used to develop the sample preparation, transmission electron microscopy and RT-PCR techniques used in this study. This virus was chosen as a replication system using baby hamster kidney cells can be used to create high concentrations of viral particles from which RNA can be extracted preventing the waste of the limited samples. The virus particles are also similar in size and morphology to the viruses to be identified in this study, as it belongs to the same family. After sample preparation, TEM analysis showed the presence of small, round, non-enveloped virus particles in the TMEV sample. Due to the low concentration of virus particles, PEG precipitation was performed using both 0.15 M and 0.25 M NaCl and 8% (w/v) PEG 6000. TEM analysis then showed an increase in viral particle concentration, with the highest concentration observed at 0.25 M NaCl and 8% PEG 6000. RNA was successfully extracted and RT-PCR assays were performed for both the VP1 and 2B coding regions of TMEV. A method for creating a positive control for the RT-PCR assay was developed by the in vitro transcription of RNA from pTMEV, which contains the cDNA of TMEV. The RNA was then used as the template for the 2B two-step RT-PCR assay. A product of 412 bp was successfully amplified from the in vitro transcribed RNA and the sensitivity of the RT-PCR assay was determined. Using a Norovirus GII positive stool sample provided by Maureen Taylor, a nested RT-PCR assay was developed for the NoV GII N/S domain using a previously-published primer set and cycling parameters. A 342 bp product was successfully amplified from the RNA extracted from the stool sample and cloned into pGEM®-T Easy to produce pNoVGII. Using the plasmid containing the AiV 5’UTR and the PCR amplicon for AiV 3CD, RT-PCR assays were developed for AiV 5’UTR and partial 3CD. The RT-PCR assays produced a 1008 bp product for AiV 5’UTR and 266 bp for AiV 3CD, which were cloned into pGEM®-T Easy to produce pAiV5’UTR and pAiV3CD, respectively. Using in vitro transcribed RNA from pNoVGII, pAiV5’UTR, pAiV3CD and pSAFV, which contains the SAFV cDNA, positive controls were developed for the RT-PCR assays for NoV GII, AiV 5’UTR, AiV 3CD and SAFV 2C. The sensitivity of these assays was determined. The samples chosen for this study include wastewater collected from the Belmont Valley water treatment plant, oysters suspected to be infected with viruses collected from Port Elizabeth, South Africa and 30 stool samples from symptomatic patients. With the methods developed using TMEV, the wastewater, oysters and 30 stool samples were filter-sterilised, concentrated and screened by TEM. All samples showed the presence of virus particles. RNA was successfully extracted and the wastewater, oyster and 30 stool samples were screened for NoV GII using the NoV GII RT-PCR assay. The wastewater, oysters and 11 of the stool samples produced the 342 bp NoV GII PCR product and BLAST analysis determined the nucleotide sequences to be NoV GII.4. This shows that this study was able to develop sample preparation techniques and TEM analysis for selected samples and RT-PCR assays for NoV GII, AiV and SAFV. The NoV GII RT-PCR assay was successfully used for the screening of the wastewater, oysters and 30 stool samples for NoV GII. Due to the high number of gastroenteritis cases with unknown aetiology in South Africa, the development of techniques for the identification of NoV, AiV, SAFV and other viruses is very important. The identification of these viruses will allow for better surveillance, treatment and prevention of gastroenteritis in South Africa.
- Full Text:
- Date Issued: 2017
The development, implementation and evaluation of a mental skills training programme for rowers at Rhodes University
- Authors: Wentworth, Tara E
- Date: 2017
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/5247 , vital:20797
- Description: In the ever increasingly competitive world of sport, there is a pressing need for training methods that have the potential to improve the performance of athletes. It is for this reason that practices associated with sport psychology (such as mental skills training) have increased in popularity. This desire for improved performance has seen a rising number of athletes seeking out the assistance of sport psychology methods. In this research, a mental skills training (MST) programme was developed and implemented into the training regime of Rhodes University rowers in Grahamstown, South Africa. The process of this research adhered to the Organisational Development Process Model’s format. Information collected from focus groups and performance profiling were utilised to design a MST programme tailored to the context of this group of athletes. This programme was implemented over one month and comprised of theoretical and practical sessions focussing on the topics of goalsetting, arousal regulation and imagery. After the programme had been completed, the participants evaluated the process in the form of individual interviews and were required to repeat the initial performance profile exercise. The results gathered from the various assessment and evaluation measures were used to compare and add to existing literature regarding MST and related disciplines. The benefits and effects of the programme have been detailed, and recommendations have been made which could possibly answer to the limitations of this research. These recommendations could provide insight into the manner in which MST programmes could possibly be more effectively implemented in future.
- Full Text:
- Date Issued: 2017
- Authors: Wentworth, Tara E
- Date: 2017
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/5247 , vital:20797
- Description: In the ever increasingly competitive world of sport, there is a pressing need for training methods that have the potential to improve the performance of athletes. It is for this reason that practices associated with sport psychology (such as mental skills training) have increased in popularity. This desire for improved performance has seen a rising number of athletes seeking out the assistance of sport psychology methods. In this research, a mental skills training (MST) programme was developed and implemented into the training regime of Rhodes University rowers in Grahamstown, South Africa. The process of this research adhered to the Organisational Development Process Model’s format. Information collected from focus groups and performance profiling were utilised to design a MST programme tailored to the context of this group of athletes. This programme was implemented over one month and comprised of theoretical and practical sessions focussing on the topics of goalsetting, arousal regulation and imagery. After the programme had been completed, the participants evaluated the process in the form of individual interviews and were required to repeat the initial performance profile exercise. The results gathered from the various assessment and evaluation measures were used to compare and add to existing literature regarding MST and related disciplines. The benefits and effects of the programme have been detailed, and recommendations have been made which could possibly answer to the limitations of this research. These recommendations could provide insight into the manner in which MST programmes could possibly be more effectively implemented in future.
- Full Text:
- Date Issued: 2017
The development, manufacture and characterisation of niosomes intended to deliver nevirapine to the brain
- Authors: Witika, Bwalya Angel
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65257 , vital:28715
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
- Authors: Witika, Bwalya Angel
- Date: 2017
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/65257 , vital:28715
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2017
The ecological impacts of pollution on a river ecosystem: a community index and stable isotope approach
- Authors: Gininda, Simphiwe Linah
- Date: 2017
- Subjects: Water -- Pollution -- Bloukrans River , Water quality -- South Africa -- Makhanda , Stream ecology -- South Africa -- Makhanda , South African Scoring System , Sewage disposal in rivers, lakes, etc. -- South Africa -- Makhanda , Agricultural ecology -- South Africa -- Makhanda , Agricultural pollution -- South Africa -- Makhanda
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/7993 , vital:21331
- Description: For decades, urbanized rivers have been modified to meet the needs of constantly expanding human populations in many countries around the world. The Bloukrans River in Grahamstown is one of the polluted and structurally modified urban rivers in South Africa, and there is no published information regarding its water quality and ecological status. Water quality is threatened by human activities including the disposal of treated and raw sewage, livestock farming, and agriculture. This study was conducted to determine the ecological status of the river by assessing its biological, chemical, and physical components in relation to man-mediated activities. Biological responses of macroinvertebrates were used to assess changes in water quality through space and time based on the South African Scoring System version 5 and the Average Score per Taxon water quality indices. The results showed poor water quality due to high nitrate and ammonium concentrations derived from sewage, and channel modifications by agricultural activities and dumping of solid waste. Channel width, water depth, dissolved oxygen, nitrate, and ammonium concentrations were the main drivers of macroinvertebrate distribution patterns and had the most influence on the variability in macroinvertebrates taxa richness, diversity and abundance. Diatoms were also used to assess water quality, specifically to indicate the trophic status of the river based on changes in the Trophic Diatom Index. The results suggested that the Bloukrans River was eutrophic during the course of this study. However, the trophic status varied with freshwater input, resulting in mesotrophic conditions during flooding and eutrophication in dry seasons. Changes in pH, phosphate concentration, water velocity (current speed), and temperature influenced the distribution of diatoms in the Bloukrans River. However, only pH was important at the community level and significantly influenced diatom abundances. Stable nitrogen isotope ratios (S15N) of autotrophs and primary and secondary consumers revealed noticeable differences between tissues of organisms exposed to treated sewage and those without any exposure. The S15N values in biota occurring above the sewage treatment discharge point were low, and those collected below the sewage point were higher. Although fertilizer derived nitrogen is generally depleted in 15N, agriculture-derived nitrogen could not be excluded as a possible source since animals at the sample site that was most affected by agricultural activities had the highest S15N values. This study provided valuable information on the ecological status of the Bloukrans River and identified the major activities associated with reduced biodiversity and water quality.
- Full Text:
- Date Issued: 2017
- Authors: Gininda, Simphiwe Linah
- Date: 2017
- Subjects: Water -- Pollution -- Bloukrans River , Water quality -- South Africa -- Makhanda , Stream ecology -- South Africa -- Makhanda , South African Scoring System , Sewage disposal in rivers, lakes, etc. -- South Africa -- Makhanda , Agricultural ecology -- South Africa -- Makhanda , Agricultural pollution -- South Africa -- Makhanda
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/7993 , vital:21331
- Description: For decades, urbanized rivers have been modified to meet the needs of constantly expanding human populations in many countries around the world. The Bloukrans River in Grahamstown is one of the polluted and structurally modified urban rivers in South Africa, and there is no published information regarding its water quality and ecological status. Water quality is threatened by human activities including the disposal of treated and raw sewage, livestock farming, and agriculture. This study was conducted to determine the ecological status of the river by assessing its biological, chemical, and physical components in relation to man-mediated activities. Biological responses of macroinvertebrates were used to assess changes in water quality through space and time based on the South African Scoring System version 5 and the Average Score per Taxon water quality indices. The results showed poor water quality due to high nitrate and ammonium concentrations derived from sewage, and channel modifications by agricultural activities and dumping of solid waste. Channel width, water depth, dissolved oxygen, nitrate, and ammonium concentrations were the main drivers of macroinvertebrate distribution patterns and had the most influence on the variability in macroinvertebrates taxa richness, diversity and abundance. Diatoms were also used to assess water quality, specifically to indicate the trophic status of the river based on changes in the Trophic Diatom Index. The results suggested that the Bloukrans River was eutrophic during the course of this study. However, the trophic status varied with freshwater input, resulting in mesotrophic conditions during flooding and eutrophication in dry seasons. Changes in pH, phosphate concentration, water velocity (current speed), and temperature influenced the distribution of diatoms in the Bloukrans River. However, only pH was important at the community level and significantly influenced diatom abundances. Stable nitrogen isotope ratios (S15N) of autotrophs and primary and secondary consumers revealed noticeable differences between tissues of organisms exposed to treated sewage and those without any exposure. The S15N values in biota occurring above the sewage treatment discharge point were low, and those collected below the sewage point were higher. Although fertilizer derived nitrogen is generally depleted in 15N, agriculture-derived nitrogen could not be excluded as a possible source since animals at the sample site that was most affected by agricultural activities had the highest S15N values. This study provided valuable information on the ecological status of the Bloukrans River and identified the major activities associated with reduced biodiversity and water quality.
- Full Text:
- Date Issued: 2017
The effect of carbohydrate on dusky kob, Argyrosomus japonicus, fed pelleted diets
- Authors: Mabasa, Nyiko Charity
- Date: 2017
- Subjects: Carbohydrates in animal nutrition , Fishes -- Feeding and feeds , Argyrosomus japonicus , Argyrosomus , Argyrosomus japonicus -- Nutrition , Argyrosomus -- Nutrition , Argyrosomus japonicus -- Feeding and feeds , Argyrosomus -- Feeding and feeds
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/44895 , vital:25450
- Description: The dusky kob, Argyrosomus japonicus, is an emerging commercial marine aquaculture species in South Africa. Attributes such as market acceptance, fast growth rates, tolerance to sibling density, acceptance of pelleted feed and adaptability to intensive aquaculture conditions make it a good candidate. Feed, the largest running cost in most aquaculture operations, is a limiting factor in dusky kob production as its nutritional requirements are not well understood. The present project formed part of a research program to develop a locally produced, least cost and sustainable feed that will support the growth and health of dusky kob. The approximate protein and energy requirements for kob fed formulated feeds have been established in earlier research, but the ability of kob to utilize carbohydrates as an energy source has not previously been investigated. The aim of this study was to determine the efficiency of dusky kob to utilize graded levels of carbohydrate (pregelatinized maize starch - PGMS) in pelleted diets. The research objectives were to determine the effect of dietary carbohydrate levels on:i) growth and feed utilization; ii) post prandial blood glucose levels; and iii) general fish health, gut bacterial composition and liver glycogen content of juvenile dusky kob. Hatchery reared juvenile dusky kob (5 g) were acclimatized in a recirculating experimental aquaculture system at the Department of Ichthyology and Fisheries Science at Rhodes University. They were fed trout crumble starter feed for three weeks before the start of the feeding experiment. Five diets containing 4.1, 8.2, 16.4 and 24.6% carbohydrate, hereafter referred to as 4.1C, 8.2C, 16.4C and 24.6C respectively, were formulated with pregelatinized maize starch as a carbohydrate source and fishmeal as the main protein source. Fish were fed these diets twice daily at 3.85% body weight per day for three months. Specific growth rates and feed conversion rations differed significantly between the four dietary treatments. Growth rate increased with increasing carbohydrate up to 16.4%, after which a significant decline was observed. Diet 16.4C produced the highest specific growth rate (SGR) of 1.84 ± 0.05% body weight/day, and the lowest feed conversion ratio of 1.28 ± 0.08. While the lowest specific growth rate and highest feed conversion ratio of 0.79 ± 0.05 and 2.14 ± 0.13 respectively, were found for diet 24.6C. A third order polynomial regression, using SGR, determined the optimum carbohydrate inclusion for dusky kob to be 16.72%. The general structure of the liver was similar between all fish fed the dietary treatments and all fish liver samples displayed a certain degree of lipid vacuolization of the hepatocytes. Evidence of starvation was observed in the livers of fish fed diet 24.6C. However, no differences in the amount of liver glycogen were observed. Gut bacterial composition did not differ among the different diets or between the different sections of the gut. Differences were however observed in the diversity of the bacterial community structure at the start (when they were fed commercial trout feed) and end of the experimental period (after being fed a fishmeal-maize diet). The rate at which glucose was cleared from the blood differed significantly between diets. The low carbohydrate diets (i.e. diet 4.1C and 8.2C) showed a steady rate of glucose removal from the blood over a 48 h experimental period. Sharp increases in blood glucose concentration were observed in diet 16.4C and diet 24.6C, with highest glucose concentrations of 7.18 ± 1.81 and 8.05 ± 2.35 mmol/l respectively, observed 24 h after feeding. The blood glucose concentration of the fish fed diet 16.4C however returned to resting glucose concentration after 48 h, while that of the fish fed diet 24.6C did not. The results demonstrated that the level of dietary carbohydrate inclusion has a significant effect on the growth and health of the fish. The optimum carbohydrate inclusion in dusky kob diets is indicated to be 16.7%, which gave the best growth rate and maximum protein sparing effect without adverse effects on fish health. These findings are important for diet formulation and producing ‘least-cost’ diets for dusky kob farming.
- Full Text:
- Date Issued: 2017
- Authors: Mabasa, Nyiko Charity
- Date: 2017
- Subjects: Carbohydrates in animal nutrition , Fishes -- Feeding and feeds , Argyrosomus japonicus , Argyrosomus , Argyrosomus japonicus -- Nutrition , Argyrosomus -- Nutrition , Argyrosomus japonicus -- Feeding and feeds , Argyrosomus -- Feeding and feeds
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/44895 , vital:25450
- Description: The dusky kob, Argyrosomus japonicus, is an emerging commercial marine aquaculture species in South Africa. Attributes such as market acceptance, fast growth rates, tolerance to sibling density, acceptance of pelleted feed and adaptability to intensive aquaculture conditions make it a good candidate. Feed, the largest running cost in most aquaculture operations, is a limiting factor in dusky kob production as its nutritional requirements are not well understood. The present project formed part of a research program to develop a locally produced, least cost and sustainable feed that will support the growth and health of dusky kob. The approximate protein and energy requirements for kob fed formulated feeds have been established in earlier research, but the ability of kob to utilize carbohydrates as an energy source has not previously been investigated. The aim of this study was to determine the efficiency of dusky kob to utilize graded levels of carbohydrate (pregelatinized maize starch - PGMS) in pelleted diets. The research objectives were to determine the effect of dietary carbohydrate levels on:i) growth and feed utilization; ii) post prandial blood glucose levels; and iii) general fish health, gut bacterial composition and liver glycogen content of juvenile dusky kob. Hatchery reared juvenile dusky kob (5 g) were acclimatized in a recirculating experimental aquaculture system at the Department of Ichthyology and Fisheries Science at Rhodes University. They were fed trout crumble starter feed for three weeks before the start of the feeding experiment. Five diets containing 4.1, 8.2, 16.4 and 24.6% carbohydrate, hereafter referred to as 4.1C, 8.2C, 16.4C and 24.6C respectively, were formulated with pregelatinized maize starch as a carbohydrate source and fishmeal as the main protein source. Fish were fed these diets twice daily at 3.85% body weight per day for three months. Specific growth rates and feed conversion rations differed significantly between the four dietary treatments. Growth rate increased with increasing carbohydrate up to 16.4%, after which a significant decline was observed. Diet 16.4C produced the highest specific growth rate (SGR) of 1.84 ± 0.05% body weight/day, and the lowest feed conversion ratio of 1.28 ± 0.08. While the lowest specific growth rate and highest feed conversion ratio of 0.79 ± 0.05 and 2.14 ± 0.13 respectively, were found for diet 24.6C. A third order polynomial regression, using SGR, determined the optimum carbohydrate inclusion for dusky kob to be 16.72%. The general structure of the liver was similar between all fish fed the dietary treatments and all fish liver samples displayed a certain degree of lipid vacuolization of the hepatocytes. Evidence of starvation was observed in the livers of fish fed diet 24.6C. However, no differences in the amount of liver glycogen were observed. Gut bacterial composition did not differ among the different diets or between the different sections of the gut. Differences were however observed in the diversity of the bacterial community structure at the start (when they were fed commercial trout feed) and end of the experimental period (after being fed a fishmeal-maize diet). The rate at which glucose was cleared from the blood differed significantly between diets. The low carbohydrate diets (i.e. diet 4.1C and 8.2C) showed a steady rate of glucose removal from the blood over a 48 h experimental period. Sharp increases in blood glucose concentration were observed in diet 16.4C and diet 24.6C, with highest glucose concentrations of 7.18 ± 1.81 and 8.05 ± 2.35 mmol/l respectively, observed 24 h after feeding. The blood glucose concentration of the fish fed diet 16.4C however returned to resting glucose concentration after 48 h, while that of the fish fed diet 24.6C did not. The results demonstrated that the level of dietary carbohydrate inclusion has a significant effect on the growth and health of the fish. The optimum carbohydrate inclusion in dusky kob diets is indicated to be 16.7%, which gave the best growth rate and maximum protein sparing effect without adverse effects on fish health. These findings are important for diet formulation and producing ‘least-cost’ diets for dusky kob farming.
- Full Text:
- Date Issued: 2017
The effect of different seating conditions, in aircrafts, on passenger comfort and the use of cabin space
- Authors: Olley, Emma-Jane
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/19734 , vital:22479
- Description: Although aircraft cabin design has improved over the years, passengers continue to complain about sitting discomfort whilst flying. These complaints are often centred on the cramped and restricted seating conditions. Whilst passenger comfort is important, in order for airline companies to attract and retain customers, it is also important to design for cabin space needs. Denel Aviation intends to build a South African Regional Aircraft (SARA) that will fly point-to-point, linking regional centres and intends to design aircraft seats that not only optimise passenger comfort, but which also save cabin space. The aim of this investigation was two-fold. The first aim was to determine how aircraft backrest angle affected passenger comfort, ease of seat access, perceived restriction and legroom, with different seat pan angles and seat heights. The second aim was to determine whether passenger comfort was affected with the most preferred backrest angle for each seat pan angle and seat height. Determining how seat pan angle and seat height affect the preferred angle of the backrest was considered important as Denel intend to use aircraft seats with a non-adjustable backrest angle. For this study, 80 participants were recruited from Rhodes University and the general Grahamstown population. The participants consisted of 40 males and 40 females and were not limited by race, ethnicity or culture. The participants were classified into two age groups; 18-30 years of age and 31-60 years of age. Participant stature, body mass, BMI and lower leg length was recorded to determine the effect these factors had on sitting comfort when the participants were seated in different seating conditions. From the results obtained, it was found that, by altering seat height, seat pan angle, and backrest angle, passenger comfort can be optimised. Furthermore, it was found that certain combinations of seat height, seat pan angle and backrest angle are more beneficial with regards to saving aircraft cabin space. However, this means that a compromise needs to be found for SARA as passenger comfort needs to be optimised, whilst decreasing the use of cabin space to reduce costs.
- Full Text:
- Date Issued: 2017
- Authors: Olley, Emma-Jane
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/19734 , vital:22479
- Description: Although aircraft cabin design has improved over the years, passengers continue to complain about sitting discomfort whilst flying. These complaints are often centred on the cramped and restricted seating conditions. Whilst passenger comfort is important, in order for airline companies to attract and retain customers, it is also important to design for cabin space needs. Denel Aviation intends to build a South African Regional Aircraft (SARA) that will fly point-to-point, linking regional centres and intends to design aircraft seats that not only optimise passenger comfort, but which also save cabin space. The aim of this investigation was two-fold. The first aim was to determine how aircraft backrest angle affected passenger comfort, ease of seat access, perceived restriction and legroom, with different seat pan angles and seat heights. The second aim was to determine whether passenger comfort was affected with the most preferred backrest angle for each seat pan angle and seat height. Determining how seat pan angle and seat height affect the preferred angle of the backrest was considered important as Denel intend to use aircraft seats with a non-adjustable backrest angle. For this study, 80 participants were recruited from Rhodes University and the general Grahamstown population. The participants consisted of 40 males and 40 females and were not limited by race, ethnicity or culture. The participants were classified into two age groups; 18-30 years of age and 31-60 years of age. Participant stature, body mass, BMI and lower leg length was recorded to determine the effect these factors had on sitting comfort when the participants were seated in different seating conditions. From the results obtained, it was found that, by altering seat height, seat pan angle, and backrest angle, passenger comfort can be optimised. Furthermore, it was found that certain combinations of seat height, seat pan angle and backrest angle are more beneficial with regards to saving aircraft cabin space. However, this means that a compromise needs to be found for SARA as passenger comfort needs to be optimised, whilst decreasing the use of cabin space to reduce costs.
- Full Text:
- Date Issued: 2017