Preparation, characterization and optimization of carbamazepine based pellets prepared by extrusion-spheronization technique

Title: Preparation, characterization and optimization of carbamazepine based pellets prepared by extrusion-spheronization technique
Creator: Makoni, Kudzai Gabriella
ThesisAdvisor: Khamanga, S M M
ThesisAdvisor: Walker, Roderick
Subject: Carbamazepine
Subject: Pharmacokinetics
Subject: Anticonvulsants
Subject: Drugs -- Controlled release
Subject: Drugs -- Dosage forms
Subject: Tablets (Medicine)
Subject: Drugs -- Administration
Subject: High performance liquid chromatography
Subject: International Conference on Harmonisation
Subject: Experimental design
Date: 2020-04
Type: Thesis
Type: Masters
Type: MSc (Pharmacy)
Identifier: http://hdl.handle.net/10962/140478
Identifier: vital:37893
Description: Carbamazepine (CBZ) is an oral antiepileptic drug (AED) that is prescribed as a first-line treatment for partial seizures. CBZ is a class II compound according to the Biopharmaceutical Classification System (BCS), hence it exhibits low aqueous solubility and high gastrointestinal tract (GIT) permeability...
Format: 216 pages, pdf
Publisher: Rhodes University, Faculty of Pharmacy, Pharmacy
Language: English
Rights: Makoni, Kudzai Gabriella

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