The relationship between acquired resistance and transmission of Schistosoma Weinland, 1858, in man and its influences on the prevalence of S Capense (Harley, 1864) and S Mansoni Sambon, 1907, in Southern Rhodesia
- Authors: Clarke, H V de V
- Date: 1965
- Subjects: Platyhelminthes , Schistosoma , Schistosomiasis
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:5842 , http://hdl.handle.net/10962/d1010500 , Platyhelminthes , Schistosoma , Schistosomiasis
- Description: Bilharziasis ranks with Tuberculosis and Malaria as the three most important endemic diseases of man in Rhodesia. The prominence given to bilharziasis in the endemic diseases pattern arises from its high prevalence, particularly in the African population. It is probable that bilharziasis was endemic in the country even prior to the arrival in the conntry of the European settlers in 1890, but it was not until Orpen (1915) described the results of a small survey that local infections were proven. He reported 182 (31 percent) urinary infections in 592 African prisoners examined in the Salisbury gaol. In the ensuing 15 years there was only scanty evidence of the prevalence of the disease. However, in the decade 1931 to 1940 the Annual Public Health Reports of Southern Rhodesia indicated increasing prevalence, and this stimulated interest in the problem and led to the establishment in 1939 of a specialised laboratory to study the parasites causing the disease. The unpublished records of this laboratory indicate that in more recent years the disease has increased not only in prevalence but also in its intensity in infected individuals. Surveys show that the urinary form of the disease is more widespread than the intestinal form. Both forms are becoming more prevalent but the rapid increase of the latter, considered by most authorities to be the more severe, indicates that a greater importance must be accorded to it in the future. Introduction, p. 1.
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- Date Issued: 1965
Studies on the neuro-physiology of a free-living Platyhelminth
- Authors: Boyle, Sheila A
- Date: 1961
- Subjects: Platyhelminthes
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5902 , http://hdl.handle.net/10962/d1013541
- Description: From Resumé: The general picture of the physiology of invertebrate neuro-muscular systems as contrasted with the classical vertebrate system is presented and it is clear that one of the groups least investigated is the Phylum Platyhelminthes. An examination of the properties of the myo-neural system of a platyhelminth should be of interest, not only in itself, but also because of a possible relationship with the coelenterates, whose neuro-muscular system has been fairly extensively investigated. The aim of the present work was to determine some of the properties of the myo-neural system of a platyhelminth, and more especially those which would make possible a comparison with the myo-neural systems of other invertebrate phyla, and most particularly with the coelenterates. A preparation consisting of an entire decerebrate animal was used. The general anatomy of the musculature and basic plan of the nervous system are presented to facilitate an understanding of the experiments described, but a detailed examination of the relationships of nerves and muscles or of the innervation of the latter was not attempted. The spontaneous activity of such preparations was recorded kymographically and the characteristics of this activity under 'normal' conditions are described, together with observations on the effects on the normal spontaneous activity of treatments with sea waters of different ionic composition and with a number of drugs. The responses of the preparation to controlled electrical stimulation are also reported. The results are analysed and compared with the results of similar investigations on other invertebrate preparations, in particular the Anthozoa, and an interpretation of these results in terms of platyhelminth-coelenterate relations is discussed.
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- Date Issued: 1961