Control and integrability on SO (3)
- Authors: Remsing, C C
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6787 , http://hdl.handle.net/10962/d1006938
- Description: This paper considers control ane left- invariant systems evolving on matrix Lie groups. Such systems have signicant applications in a variety of elds. Any left-invariant optimal control problem (with quadratic cost) can be lifted, via the celebrated Maximum Principle, to a Hamiltonian system on the dual of the Lie algebra of the underlying state space G. The (minus) Lie-Poisson structure on the dual space g is used to describe the (normal) extremal curves. An interesting, and rather typical, single-input con- trol system on the rotation group SO (3) is investi- gated in some detail. The reduced Hamilton equa- tions associated with an extremal curve are derived in a simple and elegant manner. Finally, these equations are explicitly integrated by Jacobi elliptic functions.
- Full Text:
- Date Issued: 2010
- Authors: Remsing, C C
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6787 , http://hdl.handle.net/10962/d1006938
- Description: This paper considers control ane left- invariant systems evolving on matrix Lie groups. Such systems have signicant applications in a variety of elds. Any left-invariant optimal control problem (with quadratic cost) can be lifted, via the celebrated Maximum Principle, to a Hamiltonian system on the dual of the Lie algebra of the underlying state space G. The (minus) Lie-Poisson structure on the dual space g is used to describe the (normal) extremal curves. An interesting, and rather typical, single-input con- trol system on the rotation group SO (3) is investi- gated in some detail. The reduced Hamilton equa- tions associated with an extremal curve are derived in a simple and elegant manner. Finally, these equations are explicitly integrated by Jacobi elliptic functions.
- Full Text:
- Date Issued: 2010
Developing an ionospheric map for South Africa
- McKinnell, Lee-Anne, Okoh, D I, Cilliers, P J
- Authors: McKinnell, Lee-Anne , Okoh, D I , Cilliers, P J
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6822 , http://hdl.handle.net/10962/d1004438 , http://dx.doi.org/10.5194/angeo-28-1431-2010
- Description: The development of a map of the ionosphere over South Africa is presented in this paper. The International Reference Ionosphere (IRI) model, South African Bottomside Ionospheric Model (SABIM), and measurements from ionosondes in the South African Ionosonde Network, were combined within their own limitations to develop an accurate representation of the South African ionosphere. The map is essentially in the form of a computer program that shows spatial and temporal representations of the South African ionosphere for a given set of geophysical parameters. A validation of the map is attempted using a comparison of Total Electron Content (TEC) values derived from the map, from the IRI model, and from Global Positioning System (GPS) measurements. It is foreseen that the final South African ionospheric map will be implemented as a Space Weather product of the African Space Weather Regional Warning Centre.
- Full Text:
- Date Issued: 2010
- Authors: McKinnell, Lee-Anne , Okoh, D I , Cilliers, P J
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6822 , http://hdl.handle.net/10962/d1004438 , http://dx.doi.org/10.5194/angeo-28-1431-2010
- Description: The development of a map of the ionosphere over South Africa is presented in this paper. The International Reference Ionosphere (IRI) model, South African Bottomside Ionospheric Model (SABIM), and measurements from ionosondes in the South African Ionosonde Network, were combined within their own limitations to develop an accurate representation of the South African ionosphere. The map is essentially in the form of a computer program that shows spatial and temporal representations of the South African ionosphere for a given set of geophysical parameters. A validation of the map is attempted using a comparison of Total Electron Content (TEC) values derived from the map, from the IRI model, and from Global Positioning System (GPS) measurements. It is foreseen that the final South African ionospheric map will be implemented as a Space Weather product of the African Space Weather Regional Warning Centre.
- Full Text:
- Date Issued: 2010
Development of a stability-indicating high performance liquid chromatographic method for the analysis of topiramate and dissolution rate testing in topiramate tablets
- Mohammadi, Ali, Rezanour, Nasrin, Ansari Dogaheh, M, Walker, Roderick B
- Authors: Mohammadi, Ali , Rezanour, Nasrin , Ansari Dogaheh, M , Walker, Roderick B
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6412 , http://hdl.handle.net/10962/d1006507
- Description: A stability-indicating high performance liquid chromatographic(HPLC) method was developed and validated for the quantitation and dissolution determination of topiramate in tablet dosage forms. An isocratic separation was achieved using a phenyl column with a flow rate of 1 mL/min using UV detection at 264 nm. Topiramate has low UV absorbtivity and was subjected to derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl). The mobile phase for the separation consisted of acetonitrile: 50 mM sodium dihydrogen phosphate(NaH2PO4) containing 3 % v/v triethylamine (pH 2.8) in a 48:52 v/v ratio. Topiramate was subjected to oxidation, hydrolysis, photolysis and heat for the purposes of stress testing. Separation was achieved for the parent compound and all the degradation products in an overall analytical run time of approximately 15 min with the parent compound topiramate eluting at approximately 9.2 min. The method was linear over the concentration range of 1-100 μg/mL (r = 0.9996) with limits of quantitation and detection of 1 and 0.3 μg/mL, respectively.
- Full Text:
- Date Issued: 2010
- Authors: Mohammadi, Ali , Rezanour, Nasrin , Ansari Dogaheh, M , Walker, Roderick B
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6412 , http://hdl.handle.net/10962/d1006507
- Description: A stability-indicating high performance liquid chromatographic(HPLC) method was developed and validated for the quantitation and dissolution determination of topiramate in tablet dosage forms. An isocratic separation was achieved using a phenyl column with a flow rate of 1 mL/min using UV detection at 264 nm. Topiramate has low UV absorbtivity and was subjected to derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl). The mobile phase for the separation consisted of acetonitrile: 50 mM sodium dihydrogen phosphate(NaH2PO4) containing 3 % v/v triethylamine (pH 2.8) in a 48:52 v/v ratio. Topiramate was subjected to oxidation, hydrolysis, photolysis and heat for the purposes of stress testing. Separation was achieved for the parent compound and all the degradation products in an overall analytical run time of approximately 15 min with the parent compound topiramate eluting at approximately 9.2 min. The method was linear over the concentration range of 1-100 μg/mL (r = 0.9996) with limits of quantitation and detection of 1 and 0.3 μg/mL, respectively.
- Full Text:
- Date Issued: 2010
Ecological impacts of small dams on South African rivers Part 2: Biotic response – abundance and composition of macroinvertebrate communities
- Mantel, Sukhmani K, Muller, Nikite W J, Hughes, Denis A
- Authors: Mantel, Sukhmani K , Muller, Nikite W J , Hughes, Denis A
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:7095 , http://hdl.handle.net/10962/d1012437
- Description: This paper investigates the cumulative impacts of small dams on invertebrate communities in 2 regions of South Africa – the Western Cape and Mpumalanga. Previous research found reduced discharge, increased total dissolved salts, and a decrease in average score per taxon (ASPT; collected using SASS4 methods) at sites with high density of small dams in their catchment. These changes in ASPT are investigated using the invertebrate abundance data available in the River Health Programme. Multivariate analyses found differences in invertebrate communities in rivers with high densities of small dams in their catchment in foothill-gravel streams (in both Western Cape and Mpumalanga) and in foothill-cobble streams (in Western Cape only). Opportunistic taxa that are tolerant of pollution, and capable of exploiting various habitats, and those that prefer slower currents increased in numbers, while other taxa that are sensitive to pollution and disturbance declined in numbers. Some regional differences were noted possibly reflecting climatic differences between the regions. Since the results of this study are correlative, it highlights the need for a systematic (by sites and seasons) and detailed (at species level) collection of data to verify the results of cumulative effects of small dams. This can further the development of a framework for small-dam construction and management that will limit their impact on river catchments.
- Full Text:
- Date Issued: 2010
- Authors: Mantel, Sukhmani K , Muller, Nikite W J , Hughes, Denis A
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:7095 , http://hdl.handle.net/10962/d1012437
- Description: This paper investigates the cumulative impacts of small dams on invertebrate communities in 2 regions of South Africa – the Western Cape and Mpumalanga. Previous research found reduced discharge, increased total dissolved salts, and a decrease in average score per taxon (ASPT; collected using SASS4 methods) at sites with high density of small dams in their catchment. These changes in ASPT are investigated using the invertebrate abundance data available in the River Health Programme. Multivariate analyses found differences in invertebrate communities in rivers with high densities of small dams in their catchment in foothill-gravel streams (in both Western Cape and Mpumalanga) and in foothill-cobble streams (in Western Cape only). Opportunistic taxa that are tolerant of pollution, and capable of exploiting various habitats, and those that prefer slower currents increased in numbers, while other taxa that are sensitive to pollution and disturbance declined in numbers. Some regional differences were noted possibly reflecting climatic differences between the regions. Since the results of this study are correlative, it highlights the need for a systematic (by sites and seasons) and detailed (at species level) collection of data to verify the results of cumulative effects of small dams. This can further the development of a framework for small-dam construction and management that will limit their impact on river catchments.
- Full Text:
- Date Issued: 2010
Empirically modelled Pc3 activity based on solar wind parameters
- Heilig, B, Lotz, S I, Verő, J, Sutcliffe, P, Reda, J, Pajunpää, G, Raita, T
- Authors: Heilig, B , Lotz, S I , Verő, J , Sutcliffe, P , Reda, J , Pajunpää, G , Raita, T
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6814 , http://hdl.handle.net/10962/d1004324
- Description: It is known that under certain solar wind (SW)/interplanetary magnetic field (IMF) conditions (e.g. high SW speed, low cone angle) the occurrence of ground-level Pc3–4 pulsations is more likely. In this paper we demonstrate that in the event of anomalously low SW particle density, Pc3 activity is extremely low regardless of otherwise favourable SW speed and cone angle. We re-investigate the SW control of Pc3 pulsation activity through a statistical analysis and two empirical models with emphasis on the influence of SW density on Pc3 activity. We utilise SW and IMF measurements from the OMNI project and ground-based magnetometer measurements from the MM100 array to relate SW and IMF measurements to the occurrence of Pc3 activity. Multiple linear regression and artificial neural network models are used in iterative processes in order to identify sets of SW-based input parameters, which optimally reproduce a set of Pc3 activity data. The inclusion of SW density in the parameter set significantly improves the models. Not only the density itself, but other density related parameters, such as the dynamic pressure of the SW, or the standoff distance of the magnetopause work equally well in the model. The disappearance of Pc3s during low-density events can have at least four reasons according to the existing upstream wave theory: 1. Pausing the ion-cyclotron resonance that generates the upstream ultra low frequency waves in the absence of protons, 2. Weakening of the bow shock that implies less efficient reflection, 3. The SW becomes sub-Alfvénic and hence it is not able to sweep back the waves propagating upstream with the Alfvén-speed, and 4. The increase of the standoff distance of the magnetopause (and of the bow shock). Although the models cannot account for the lack of Pc3s during intervals when the SW density is extremely low, the resulting sets of optimal model inputs support the generation of mid latitude Pc3 activity predominantly through upstream waves.
- Full Text:
- Date Issued: 2010
- Authors: Heilig, B , Lotz, S I , Verő, J , Sutcliffe, P , Reda, J , Pajunpää, G , Raita, T
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6814 , http://hdl.handle.net/10962/d1004324
- Description: It is known that under certain solar wind (SW)/interplanetary magnetic field (IMF) conditions (e.g. high SW speed, low cone angle) the occurrence of ground-level Pc3–4 pulsations is more likely. In this paper we demonstrate that in the event of anomalously low SW particle density, Pc3 activity is extremely low regardless of otherwise favourable SW speed and cone angle. We re-investigate the SW control of Pc3 pulsation activity through a statistical analysis and two empirical models with emphasis on the influence of SW density on Pc3 activity. We utilise SW and IMF measurements from the OMNI project and ground-based magnetometer measurements from the MM100 array to relate SW and IMF measurements to the occurrence of Pc3 activity. Multiple linear regression and artificial neural network models are used in iterative processes in order to identify sets of SW-based input parameters, which optimally reproduce a set of Pc3 activity data. The inclusion of SW density in the parameter set significantly improves the models. Not only the density itself, but other density related parameters, such as the dynamic pressure of the SW, or the standoff distance of the magnetopause work equally well in the model. The disappearance of Pc3s during low-density events can have at least four reasons according to the existing upstream wave theory: 1. Pausing the ion-cyclotron resonance that generates the upstream ultra low frequency waves in the absence of protons, 2. Weakening of the bow shock that implies less efficient reflection, 3. The SW becomes sub-Alfvénic and hence it is not able to sweep back the waves propagating upstream with the Alfvén-speed, and 4. The increase of the standoff distance of the magnetopause (and of the bow shock). Although the models cannot account for the lack of Pc3s during intervals when the SW density is extremely low, the resulting sets of optimal model inputs support the generation of mid latitude Pc3 activity predominantly through upstream waves.
- Full Text:
- Date Issued: 2010
First oceanographic survey of the entire continental shelf adjacent to the northern Agulhas Current
- Lutjeharms, Johan R E, Durgadoo, Jonathan V, Schapira, Mathilde, McQuaid, Christopher D
- Authors: Lutjeharms, Johan R E , Durgadoo, Jonathan V , Schapira, Mathilde , McQuaid, Christopher D
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6867 , http://hdl.handle.net/10962/d1011499 , http://www.sajs.co.za/index.php/SAJS/article/view/410
- Description: [from introduction] The Agulhas Current is by far the largest western boundary current of the southern hemisphere1 and carries about 70 × 106 m3/s of seawater past the eastern shores of South Africa.2 Being more than 2000 m deep, it follows the continental shelf edge quite closely. Its northern part, all the way downstream to Algoa Bay, has a very stable trajectory whereas the southern part meanders widely to either side of a mean geographical location,3 in the process creating shear edge eddies and attendant plumes of warm surface water over the shelf.4 However, the direct influence of the Agulhas Current on the waters and ecosystems of the adjacent shelf of South Africa remains largely unknown.
- Full Text:
- Date Issued: 2010
- Authors: Lutjeharms, Johan R E , Durgadoo, Jonathan V , Schapira, Mathilde , McQuaid, Christopher D
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6867 , http://hdl.handle.net/10962/d1011499 , http://www.sajs.co.za/index.php/SAJS/article/view/410
- Description: [from introduction] The Agulhas Current is by far the largest western boundary current of the southern hemisphere1 and carries about 70 × 106 m3/s of seawater past the eastern shores of South Africa.2 Being more than 2000 m deep, it follows the continental shelf edge quite closely. Its northern part, all the way downstream to Algoa Bay, has a very stable trajectory whereas the southern part meanders widely to either side of a mean geographical location,3 in the process creating shear edge eddies and attendant plumes of warm surface water over the shelf.4 However, the direct influence of the Agulhas Current on the waters and ecosystems of the adjacent shelf of South Africa remains largely unknown.
- Full Text:
- Date Issued: 2010
Framework for local government to implement integrated water resource management linked to water service delivery
- Haigh, Eliria H, Fox, Helen E, Davies-Coleman, Heather D
- Authors: Haigh, Eliria H , Fox, Helen E , Davies-Coleman, Heather D
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:7097 , http://hdl.handle.net/10962/d1012440
- Description: The Water Services Act (No. 8 of 1997) of South Africa states that water service delivery is the responsibility of local government as Water Services Authorities. The principal legal responsibility is to complete a Water Services Development Plan (WSDP) every 5 years with annual review. The WSDP encapsulates all the responsibilities and tasks required in water service delivery. However, it does not spell out local government’s role in water resource protection or its responsibilities as far as integrated water resource management is concerned. It is well known in South Africa that there is a challenging level of inadequate capacity in technical and administrative skills in local government to adequately fulfil water service delivery. This paper highlights the consequences of this incapacity for municipalities and their difficulties in fulfilling their responsibilities as service providers. A framework is provided within which improvements can be brought about, with guidance on how to engage in the practice of integrated water resource management (IWRM) in the context of the legal framework for water services. The additional tasks and changes required to practise IWRM are set in the context of the WSDP. The framework provides a guide for a municipality to first accomplish an adequate WSDP, and then to gradually implement IWRM. A discussion on the skills needed to accomplish, firstly, a comprehensive WSDP, and secondly, IWRM, is included.
- Full Text:
- Date Issued: 2010
- Authors: Haigh, Eliria H , Fox, Helen E , Davies-Coleman, Heather D
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:7097 , http://hdl.handle.net/10962/d1012440
- Description: The Water Services Act (No. 8 of 1997) of South Africa states that water service delivery is the responsibility of local government as Water Services Authorities. The principal legal responsibility is to complete a Water Services Development Plan (WSDP) every 5 years with annual review. The WSDP encapsulates all the responsibilities and tasks required in water service delivery. However, it does not spell out local government’s role in water resource protection or its responsibilities as far as integrated water resource management is concerned. It is well known in South Africa that there is a challenging level of inadequate capacity in technical and administrative skills in local government to adequately fulfil water service delivery. This paper highlights the consequences of this incapacity for municipalities and their difficulties in fulfilling their responsibilities as service providers. A framework is provided within which improvements can be brought about, with guidance on how to engage in the practice of integrated water resource management (IWRM) in the context of the legal framework for water services. The additional tasks and changes required to practise IWRM are set in the context of the WSDP. The framework provides a guide for a municipality to first accomplish an adequate WSDP, and then to gradually implement IWRM. A discussion on the skills needed to accomplish, firstly, a comprehensive WSDP, and secondly, IWRM, is included.
- Full Text:
- Date Issued: 2010
In-service training for academic librarians : a pilot programme for staff
- Authors: Shepherd, Eileen
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6992 , http://hdl.handle.net/10962/d1012418 , http://www.emeraldinsight.com/doi/full/10.1108/02640471011065346
- Description: This paper discusses the need for continuing professional development for librarians in academic libraries in general and at Rhodes University Library, South Africa in particular. It describes the planning, design, implementation and evaluation of a staff-development and training pilot programme for professional librarians at Rhodes Library. A group of 15 librarians, drawn from the library staff complement, participated in an 8-session training course developed by Information Services librarians. The course, which covered basic information-finding skills using a variety of research databases and offered an introduction to concepts in 21st century academic librarianship, was presented using course management software in a face-to-face environment and required homework exercises and the completion of a 2-hour final test. The results of the project demonstrated the urgent need for such development programmes for professional library staff. 80% of the participants completed the course. The final test results indicated below average database search skills and an inability to think laterally. An unexpected finding was a lack of IT competencies. Important lessons were learned with regard to course-construction, content and timing.
- Full Text:
- Date Issued: 2010
- Authors: Shepherd, Eileen
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6992 , http://hdl.handle.net/10962/d1012418 , http://www.emeraldinsight.com/doi/full/10.1108/02640471011065346
- Description: This paper discusses the need for continuing professional development for librarians in academic libraries in general and at Rhodes University Library, South Africa in particular. It describes the planning, design, implementation and evaluation of a staff-development and training pilot programme for professional librarians at Rhodes Library. A group of 15 librarians, drawn from the library staff complement, participated in an 8-session training course developed by Information Services librarians. The course, which covered basic information-finding skills using a variety of research databases and offered an introduction to concepts in 21st century academic librarianship, was presented using course management software in a face-to-face environment and required homework exercises and the completion of a 2-hour final test. The results of the project demonstrated the urgent need for such development programmes for professional library staff. 80% of the participants completed the course. The final test results indicated below average database search skills and an inability to think laterally. An unexpected finding was a lack of IT competencies. Important lessons were learned with regard to course-construction, content and timing.
- Full Text:
- Date Issued: 2010
Mechanisms of habitat segregation between an invasive (Mytilus galloprovincialis) and an indigenous (Perna perna) mussel: adult growth and mortality
- Bownes, Sarah J, McQuaid, Christopher D
- Authors: Bownes, Sarah J , McQuaid, Christopher D
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6868 , http://hdl.handle.net/10962/d1011500
- Description: The invasive mussel Mytilus galloprovincialis and the indigenous mussel Perna perna coexist intertidally on the south coast of South Africa through partial vertical habitat segregation: M. galloprovincialis dominates the upper shore and P. perna the lower shore. Recruitment patterns can explain the zonation of P. perna, but not the invasive species. We examined the role of post-recruitment interactions by measuring spatial and temporal differences in adult growth and mortality rates of the two species. Specifically, we tested the hypothesis that interspecific differences in growth and mortality reflect adult distribution patterns. The two study locations, Plettenberg Bay and Tsitsikamma, are 70 km apart with two sites (separated by 300–400 m) per location, each divided into three vertical zones. Growth was measured seasonally using different marking methods in 2001 and 2003. Cumulative adult mortality was measured through summer in 2003/2004. Both species generally grew more slowly upshore, but they showed different effects of season. For P. perna, growth was significantly reduced in winter in the low zone, but unaffected by season in the high zone. For M. galloprovincialis, growth was either unaffected by season or increased in winter, even in the high zone. Thus, growth of P. perna and M. galloprovincialis was reduced under cool winter and warm summer temperatures, respectively; and while growth was more similar between species in summer, M. galloprovincialis grew much faster than P. perna in winter. Mortality of P. perna increased upshore. For M. galloprovincialis, mortality was not zone-dependent and was significantly greater than for P. perna on the low-shore and (generally) across the shore in Tsitsikamma. Both species had higher growth and mortality rates in Plettenberg Bay than in Tsitsikamma. Thus, P. perna seems able to maintain spatial dominance on the low-shore and at certain sites because of higher mortality of M. galloprovincialis. We conclude that seasonality in growth of the two species reflects their biogeographic affinities and that coexistence is possible through pre-recruitment effects that limit the vertical distribution of P. perna and post-recruitment effects that limit M. galloprovincialis.
- Full Text:
- Date Issued: 2010
- Authors: Bownes, Sarah J , McQuaid, Christopher D
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6868 , http://hdl.handle.net/10962/d1011500
- Description: The invasive mussel Mytilus galloprovincialis and the indigenous mussel Perna perna coexist intertidally on the south coast of South Africa through partial vertical habitat segregation: M. galloprovincialis dominates the upper shore and P. perna the lower shore. Recruitment patterns can explain the zonation of P. perna, but not the invasive species. We examined the role of post-recruitment interactions by measuring spatial and temporal differences in adult growth and mortality rates of the two species. Specifically, we tested the hypothesis that interspecific differences in growth and mortality reflect adult distribution patterns. The two study locations, Plettenberg Bay and Tsitsikamma, are 70 km apart with two sites (separated by 300–400 m) per location, each divided into three vertical zones. Growth was measured seasonally using different marking methods in 2001 and 2003. Cumulative adult mortality was measured through summer in 2003/2004. Both species generally grew more slowly upshore, but they showed different effects of season. For P. perna, growth was significantly reduced in winter in the low zone, but unaffected by season in the high zone. For M. galloprovincialis, growth was either unaffected by season or increased in winter, even in the high zone. Thus, growth of P. perna and M. galloprovincialis was reduced under cool winter and warm summer temperatures, respectively; and while growth was more similar between species in summer, M. galloprovincialis grew much faster than P. perna in winter. Mortality of P. perna increased upshore. For M. galloprovincialis, mortality was not zone-dependent and was significantly greater than for P. perna on the low-shore and (generally) across the shore in Tsitsikamma. Both species had higher growth and mortality rates in Plettenberg Bay than in Tsitsikamma. Thus, P. perna seems able to maintain spatial dominance on the low-shore and at certain sites because of higher mortality of M. galloprovincialis. We conclude that seasonality in growth of the two species reflects their biogeographic affinities and that coexistence is possible through pre-recruitment effects that limit the vertical distribution of P. perna and post-recruitment effects that limit M. galloprovincialis.
- Full Text:
- Date Issued: 2010
Multiple organ failure - death of consumer protection?
- Authors: Steinman, H A , Jobson, M R
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6436 , http://hdl.handle.net/10962/d1006613
- Description: The enormously profitable complementary medicines, dietary supplements and traditional medicines markets are largely unregulated internationally and South Africa. Attempts to ensure that consumers are not exposed to harmful or ineffective products have met with varying success around the world.
- Full Text:
- Date Issued: 2010
- Authors: Steinman, H A , Jobson, M R
- Date: 2010
- Language: English
- Type: text , Article
- Identifier: vital:6436 , http://hdl.handle.net/10962/d1006613
- Description: The enormously profitable complementary medicines, dietary supplements and traditional medicines markets are largely unregulated internationally and South Africa. Attempts to ensure that consumers are not exposed to harmful or ineffective products have met with varying success around the world.
- Full Text:
- Date Issued: 2010
Optimization of salbutamol sulfate dissolution from sustained release matrix formulations using an artificial neural network
- Chaibva, Faith A, Burton, Michael, Walker, Roderick B
- Authors: Chaibva, Faith A , Burton, Michael , Walker, Roderick B
- Date: 2010
- Subjects: Neural networks (Computer science)
- Language: English
- Type: Article
- Identifier: vital:6352 , http://hdl.handle.net/10962/d1006034
- Description: An artificial neural network was used to optimize the release of salbutamol sulfate from hydrophilic matrix formulations. Model formulations to be used for training, testing and validating the neural network were manufactured with the aid of a central composite design with varying the levels of Methocel® K100M, xanthan gum, Carbopol® 974P and Surelease® as the input factors. In vitro dissolution time profiles at six different sampling times were used as target data in training the neural network for formulation optimization. A multi layer perceptron with one hidden layer was constructed using Matlab®, and the number of nodes in the hidden layer was optimized by trial and error to develop a model with the best predictive ability. The results revealed that a neural network with nine nodes was optimal for developing and optimizing formulations. Simulations undertaken with the training data revealed that the constructed model was useable. The optimized neural network was used for optimization of formulation with desirable release characteristics and the results indicated that there was agreement between the predicted formulation and the manufactured formulation. This work illustrates the possible utility of artificial neural networks for the optimization of pharmaceutical formulations with desirable performance characteristics.
- Full Text:
- Date Issued: 2010
- Authors: Chaibva, Faith A , Burton, Michael , Walker, Roderick B
- Date: 2010
- Subjects: Neural networks (Computer science)
- Language: English
- Type: Article
- Identifier: vital:6352 , http://hdl.handle.net/10962/d1006034
- Description: An artificial neural network was used to optimize the release of salbutamol sulfate from hydrophilic matrix formulations. Model formulations to be used for training, testing and validating the neural network were manufactured with the aid of a central composite design with varying the levels of Methocel® K100M, xanthan gum, Carbopol® 974P and Surelease® as the input factors. In vitro dissolution time profiles at six different sampling times were used as target data in training the neural network for formulation optimization. A multi layer perceptron with one hidden layer was constructed using Matlab®, and the number of nodes in the hidden layer was optimized by trial and error to develop a model with the best predictive ability. The results revealed that a neural network with nine nodes was optimal for developing and optimizing formulations. Simulations undertaken with the training data revealed that the constructed model was useable. The optimized neural network was used for optimization of formulation with desirable release characteristics and the results indicated that there was agreement between the predicted formulation and the manufactured formulation. This work illustrates the possible utility of artificial neural networks for the optimization of pharmaceutical formulations with desirable performance characteristics.
- Full Text:
- Date Issued: 2010
Physical and biological coupling in eddies in the lee of the South-West Indian Ridge
- Ansorge, Isabelle J, Pakhomov, E A, Kaehler, Sven, Lutjeharms, Johan R E, Durgadoo, J V
- Authors: Ansorge, Isabelle J , Pakhomov, E A , Kaehler, Sven , Lutjeharms, Johan R E , Durgadoo, J V
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6493 , http://hdl.handle.net/10962/d1004477
- Description: Eddies have some decisive functions in the dynamics of the Southern Ocean ecosystems. This is particularly true in the Indian sector of the Southern Ocean, where a region of unusually high-mesoscale variability has been observed in the vicinity of the South-West Indian Ridge. In April 2003, three eddies were studied: eddy A, a recently spawned anticyclone south of the Antarctic Polar Front (APF),; eddy B, an anticyclone north of lying between the Subantarctic Front and the APF; and eddy C, a cyclone north of the APF west of the ridge. Elevated concentrations of total Chl-a coincided with the edges of the cyclonic eddy, whereas both anticyclonic eddies A and B were characterised by low total Chl-a concentrations. Biologically, the two anticyclonic eddies A and B were distinctly different in their biogeographic origin. The zooplankton community in the larger anticyclonic eddy A was similar in composition to the Antarctic Polar Frontal Zone (APFZ) community with an addition of some Antarctic species suggesting an origin just north of the APF. In contrast, the species composition within the second anticyclonic eddy B appeared to be more typical of the transitional nature of the APFZ, comprising species of both subantarctic and subtropical origin and thus influenced by intrusions of water masses from both north and south of the Subantarctic Front. Back-tracking of these features shows that the biological composition clearly demarcates the hydrographic origin of these features.
- Full Text:
- Date Issued: 2010
- Authors: Ansorge, Isabelle J , Pakhomov, E A , Kaehler, Sven , Lutjeharms, Johan R E , Durgadoo, J V
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6493 , http://hdl.handle.net/10962/d1004477
- Description: Eddies have some decisive functions in the dynamics of the Southern Ocean ecosystems. This is particularly true in the Indian sector of the Southern Ocean, where a region of unusually high-mesoscale variability has been observed in the vicinity of the South-West Indian Ridge. In April 2003, three eddies were studied: eddy A, a recently spawned anticyclone south of the Antarctic Polar Front (APF),; eddy B, an anticyclone north of lying between the Subantarctic Front and the APF; and eddy C, a cyclone north of the APF west of the ridge. Elevated concentrations of total Chl-a coincided with the edges of the cyclonic eddy, whereas both anticyclonic eddies A and B were characterised by low total Chl-a concentrations. Biologically, the two anticyclonic eddies A and B were distinctly different in their biogeographic origin. The zooplankton community in the larger anticyclonic eddy A was similar in composition to the Antarctic Polar Frontal Zone (APFZ) community with an addition of some Antarctic species suggesting an origin just north of the APF. In contrast, the species composition within the second anticyclonic eddy B appeared to be more typical of the transitional nature of the APFZ, comprising species of both subantarctic and subtropical origin and thus influenced by intrusions of water masses from both north and south of the Subantarctic Front. Back-tracking of these features shows that the biological composition clearly demarcates the hydrographic origin of these features.
- Full Text:
- Date Issued: 2010
Politics in the slum: a view from South Africa
- Authors: Pithouse, Richard, 1970-
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6209 , http://hdl.handle.net/10962/d1008579
- Description: [From introduction]The modern state, and its civil society, have always been comfortable with workers in their allotted place – be it formed around the immediate needs of industrial production, like the migrant workers hostels in apartheid South Africa or contemporary Dubai, or an attempt at creating a haven, like the suburban home which has its roots in the gendered and raced class compromise reached in North America after the Second World War. When there has been a part of the population rendered or considered superfluous to the immediate needs of production there has been a degree of comfort with the inevitably bounded spaces into which these people have been abandoned or contained – prisons, ghettos, Bantustans etc. But both the modern state and civil society have always been acutely uncomfortable with that part of the ‘dangerous class’ - vagabonds or squatters - that are, by virtue of their occupation of space outside of state regulation, by definition out of place and threatening to domination constructed, along with other lines of force, on the ordering of space.
- Full Text:
- Date Issued: 2010
- Authors: Pithouse, Richard, 1970-
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6209 , http://hdl.handle.net/10962/d1008579
- Description: [From introduction]The modern state, and its civil society, have always been comfortable with workers in their allotted place – be it formed around the immediate needs of industrial production, like the migrant workers hostels in apartheid South Africa or contemporary Dubai, or an attempt at creating a haven, like the suburban home which has its roots in the gendered and raced class compromise reached in North America after the Second World War. When there has been a part of the population rendered or considered superfluous to the immediate needs of production there has been a degree of comfort with the inevitably bounded spaces into which these people have been abandoned or contained – prisons, ghettos, Bantustans etc. But both the modern state and civil society have always been acutely uncomfortable with that part of the ‘dangerous class’ - vagabonds or squatters - that are, by virtue of their occupation of space outside of state regulation, by definition out of place and threatening to domination constructed, along with other lines of force, on the ordering of space.
- Full Text:
- Date Issued: 2010
Present day challenges in understanding the geomagnetic hazard to national power grids
- Thompson, A W P, Kotze, P, Ngwira, C M, Lotz, Stefanus I, Gaunt, C T, Cilliers, P, Wild, J A, Opperman, Ben D L, McKinnell, Lee-Anne, Lotz, S I
- Authors: Thompson, A W P , Kotze, P , Ngwira, C M , Lotz, Stefanus I , Gaunt, C T , Cilliers, P , Wild, J A , Opperman, Ben D L , McKinnell, Lee-Anne , Lotz, S I
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6812 , http://hdl.handle.net/10962/d1004305
- Description: Power grids and pipeline networks at all latitudes are known to be at risk from the natural hazard of geomagnetically induced currents. At a recent workshop in South Africa, UK and South African scientists and engineers discussed the current understanding of this hazard, as it affects major power systems in Europe and Africa. They also summarised, to better inform the public and industry, what can be said with some certainty about the hazard and what research is yet required to develop useful tools for geomagnetic hazard mitigation.
- Full Text:
- Date Issued: 2010
- Authors: Thompson, A W P , Kotze, P , Ngwira, C M , Lotz, Stefanus I , Gaunt, C T , Cilliers, P , Wild, J A , Opperman, Ben D L , McKinnell, Lee-Anne , Lotz, S I
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6812 , http://hdl.handle.net/10962/d1004305
- Description: Power grids and pipeline networks at all latitudes are known to be at risk from the natural hazard of geomagnetically induced currents. At a recent workshop in South Africa, UK and South African scientists and engineers discussed the current understanding of this hazard, as it affects major power systems in Europe and Africa. They also summarised, to better inform the public and industry, what can be said with some certainty about the hazard and what research is yet required to develop useful tools for geomagnetic hazard mitigation.
- Full Text:
- Date Issued: 2010
Public green space inequality in small towns in South Africa
- McConnachie, Matthew M, Shackleton, Charlie M
- Authors: McConnachie, Matthew M , Shackleton, Charlie M
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6644 , http://hdl.handle.net/10962/d1006874
- Description: The distribution of public green space within towns is frequently uneven, and influenced by attributes such as its location relative to the commercial core, as well as the ethnicity and relative wealth and education of the residents. Yet most studies are from large cities in developed countries. In contrast, this study reports on the distribution of public green space across 9 small towns in a developing country, namely South Africa, which offers a unique case study because of its former racially defined settlement patterns. We do so using GIS analysis of aerial photographs focusing on 3 types of suburbs in each town, defined on the basis of wealth as well as race-based history under the previous apartheid regime. The more affluent suburbs, inhabited mainly by whites, have the lowest density of housing and the highest area of green space per capita. Proportionally, they have a similar area under public green space as to the previously racially defined townships, but because of the lower housing density, they have a greater area per person. The newly built low-cost housing areas (termed RDP suburbs), occupied largely by poor black South Africans, are poorly endowed with public green space, and fare worse than the other 2 suburb types on all attributes measured. This needs to be addressed in further low-cost housing developments.
- Full Text:
- Date Issued: 2010
- Authors: McConnachie, Matthew M , Shackleton, Charlie M
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6644 , http://hdl.handle.net/10962/d1006874
- Description: The distribution of public green space within towns is frequently uneven, and influenced by attributes such as its location relative to the commercial core, as well as the ethnicity and relative wealth and education of the residents. Yet most studies are from large cities in developed countries. In contrast, this study reports on the distribution of public green space across 9 small towns in a developing country, namely South Africa, which offers a unique case study because of its former racially defined settlement patterns. We do so using GIS analysis of aerial photographs focusing on 3 types of suburbs in each town, defined on the basis of wealth as well as race-based history under the previous apartheid regime. The more affluent suburbs, inhabited mainly by whites, have the lowest density of housing and the highest area of green space per capita. Proportionally, they have a similar area under public green space as to the previously racially defined townships, but because of the lower housing density, they have a greater area per person. The newly built low-cost housing areas (termed RDP suburbs), occupied largely by poor black South Africans, are poorly endowed with public green space, and fare worse than the other 2 suburb types on all attributes measured. This needs to be addressed in further low-cost housing developments.
- Full Text:
- Date Issued: 2010
Quantifying the annual fish harvest from South Africa’s largest freshwater reservoir
- Ellender, Bruce R, Weyl, Olaf L F, Winker, A Henning, Booth, Anthony J
- Authors: Ellender, Bruce R , Weyl, Olaf L F , Winker, A Henning , Booth, Anthony J
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:7149 , http://hdl.handle.net/10962/d1011852
- Description: South African inland fisheries are poorly developed and their contribution to near-shore communities is poorly understood. This study is the first comprehensive assessment of recreational and subsistence angling undertaken in an inland fishery in South Africa. The study was conducted on the 360 km2 Lake Gariep, South Africa’s largest freshwater reservoir. A total of 508 anglers were interviewed between February 2007 and January 2008. Of those interviewed, 67% were subsistence anglers and 33% recreational anglers. Catch per unit effort (CPUE) did not differ significantly between sectors. CPUE fluctuated seasonally, ranging between 0.37 (95% CI= 0.26 to 0.51) kg·angler-1·h-1 in winter and 0.88 (0.67 to 1.17) kg·angler- 1·h-1 in summer. The duration of a fishing day ranged from 5.99 (5.24 to 6.74) h in mid-winter to 7.26 (6.88 to 7.63) h in early summer. Expected end-of-day catch (CPUE × fishing-trip duration) ranged from 2.2 to 6.4 kg·angler-1·d-1 depending on the season. The number of anglers ranged from 22 (8 to 53) anglers·d-1 in June/July to 74 (25 to 176) anglers·d-1 in April. Total annual catch from the roving creel survey was estimated at 71.4 (57.4 to 91.4) t·yr-1. Another 7.5 t∙yr-1 were landed during recreational angling competitions. The resultant total catch divided by the lakeshore population equated to a per capita fish supply of 11.1 kg·yr-1. More than 70% of the catch was the alien invasive carp Cyprinus carpio and there was no evidence of overfishing. The fish resource of Lake Gariep is of significant recreational and subsistence value. As a result of the low fish price (ZAR5.72 ± 2.60·kg-1) subsistence fishing was considered a low-revenue activity that mainly augmented food security in lakeshore communities. The relatively high CPUE indicated that the fishery may be an important safety-net during periods when alternate sources of livelihoods are limited. Consequently, we recommend that the importance of angling to local communities needs to be taken into account when planning fisheries development and developing an inland fisheries policy
- Full Text:
- Date Issued: 2010
- Authors: Ellender, Bruce R , Weyl, Olaf L F , Winker, A Henning , Booth, Anthony J
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:7149 , http://hdl.handle.net/10962/d1011852
- Description: South African inland fisheries are poorly developed and their contribution to near-shore communities is poorly understood. This study is the first comprehensive assessment of recreational and subsistence angling undertaken in an inland fishery in South Africa. The study was conducted on the 360 km2 Lake Gariep, South Africa’s largest freshwater reservoir. A total of 508 anglers were interviewed between February 2007 and January 2008. Of those interviewed, 67% were subsistence anglers and 33% recreational anglers. Catch per unit effort (CPUE) did not differ significantly between sectors. CPUE fluctuated seasonally, ranging between 0.37 (95% CI= 0.26 to 0.51) kg·angler-1·h-1 in winter and 0.88 (0.67 to 1.17) kg·angler- 1·h-1 in summer. The duration of a fishing day ranged from 5.99 (5.24 to 6.74) h in mid-winter to 7.26 (6.88 to 7.63) h in early summer. Expected end-of-day catch (CPUE × fishing-trip duration) ranged from 2.2 to 6.4 kg·angler-1·d-1 depending on the season. The number of anglers ranged from 22 (8 to 53) anglers·d-1 in June/July to 74 (25 to 176) anglers·d-1 in April. Total annual catch from the roving creel survey was estimated at 71.4 (57.4 to 91.4) t·yr-1. Another 7.5 t∙yr-1 were landed during recreational angling competitions. The resultant total catch divided by the lakeshore population equated to a per capita fish supply of 11.1 kg·yr-1. More than 70% of the catch was the alien invasive carp Cyprinus carpio and there was no evidence of overfishing. The fish resource of Lake Gariep is of significant recreational and subsistence value. As a result of the low fish price (ZAR5.72 ± 2.60·kg-1) subsistence fishing was considered a low-revenue activity that mainly augmented food security in lakeshore communities. The relatively high CPUE indicated that the fishery may be an important safety-net during periods when alternate sources of livelihoods are limited. Consequently, we recommend that the importance of angling to local communities needs to be taken into account when planning fisheries development and developing an inland fisheries policy
- Full Text:
- Date Issued: 2010
Quest for space : Rhodes University Library odyssey 1904-2010
- Authors: Van der Riet, Sue
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6995 , http://hdl.handle.net/10962/d1012424
- Description: The completion in 2010 of the magnificent new and expanded Rhodes University Library, billed as Rhodes' most intelligent building, seems an appropriate time to trace its history and reflect on the events that led to this much-needed facility and the enormous amount of planning, canvassing, pleading, persuasion and fundraising that brought it to fruition. It is the nature of libraries to devour space. Collections grow exponentially, creating a voracious and insatiable appetite for more and more places in which to store them. In addition, as users’ needs change over time, there is an ongoing demand for working areas which are versatile, able to accommodate modern paradigms of teaching and learning which now necessitate group study areas with computer access, yet which remain inviting and attractive to a broad range of students and researchers who wish simply to find a congenial space to study. The ongoing shortage of space, and the need to accommodate evolving patterns of use, common to most academic libraries, fuelled the engine which drove the Rhodes Library on its circuitous journey from humble lodgings in a single room in the old Drostdy Building more than a hundred years ago, to its final destination in the imposing position it occupies today. A constant refrain was to be money – or more aptly, the lack of it.
- Full Text:
- Date Issued: 2010
- Authors: Van der Riet, Sue
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6995 , http://hdl.handle.net/10962/d1012424
- Description: The completion in 2010 of the magnificent new and expanded Rhodes University Library, billed as Rhodes' most intelligent building, seems an appropriate time to trace its history and reflect on the events that led to this much-needed facility and the enormous amount of planning, canvassing, pleading, persuasion and fundraising that brought it to fruition. It is the nature of libraries to devour space. Collections grow exponentially, creating a voracious and insatiable appetite for more and more places in which to store them. In addition, as users’ needs change over time, there is an ongoing demand for working areas which are versatile, able to accommodate modern paradigms of teaching and learning which now necessitate group study areas with computer access, yet which remain inviting and attractive to a broad range of students and researchers who wish simply to find a congenial space to study. The ongoing shortage of space, and the need to accommodate evolving patterns of use, common to most academic libraries, fuelled the engine which drove the Rhodes Library on its circuitous journey from humble lodgings in a single room in the old Drostdy Building more than a hundred years ago, to its final destination in the imposing position it occupies today. A constant refrain was to be money – or more aptly, the lack of it.
- Full Text:
- Date Issued: 2010
Reflecting on the next generation of models for community-based natural resources management
- Shackleton, Charlie M, Willis, T V, Brown, K, Polunin, N
- Authors: Shackleton, Charlie M , Willis, T V , Brown, K , Polunin, N
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6659 , http://hdl.handle.net/10962/d1007083
- Description: Community-based natural resource management (CBNRM) has been a pervasive paradigm in conservation circles for three decades. Despite many potentially attractive attributes it has been extensively critiqued from both ecological and sociological perspectives with respect to theory and practice (for example Leach et al. 1999; Berkes 2004; Fabricius et al. 2004; Blaikie 2006). Nonetheless, many successful examples exist, although an equal number have seemingly not met expectations. Is this because of poor implementation or rather a generally flawed model? If the criteria and conditions for success are so onerous that relatively few projects or situations are likely to qualify, what then is the value of the model? The questions thus become: how and what can we learn from the past theory and practice to develop a new generation of flexible, locally responsive and implementable CBNRM models, and what are likely to be the attributes of such models?
- Full Text:
- Date Issued: 2010
- Authors: Shackleton, Charlie M , Willis, T V , Brown, K , Polunin, N
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6659 , http://hdl.handle.net/10962/d1007083
- Description: Community-based natural resource management (CBNRM) has been a pervasive paradigm in conservation circles for three decades. Despite many potentially attractive attributes it has been extensively critiqued from both ecological and sociological perspectives with respect to theory and practice (for example Leach et al. 1999; Berkes 2004; Fabricius et al. 2004; Blaikie 2006). Nonetheless, many successful examples exist, although an equal number have seemingly not met expectations. Is this because of poor implementation or rather a generally flawed model? If the criteria and conditions for success are so onerous that relatively few projects or situations are likely to qualify, what then is the value of the model? The questions thus become: how and what can we learn from the past theory and practice to develop a new generation of flexible, locally responsive and implementable CBNRM models, and what are likely to be the attributes of such models?
- Full Text:
- Date Issued: 2010
Simultaneous determination of irinotecan hydrochloride and its related compounds by high performance liquid chromatography using ultraviolet detection
- Mohammadi, Ali, Esmaeili, Farnaz, Dinarvand, Rassoul, Atyabi, Fatemeh, Walker, Roderick B
- Authors: Mohammadi, Ali , Esmaeili, Farnaz , Dinarvand, Rassoul , Atyabi, Fatemeh , Walker, Roderick B
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6413 , http://hdl.handle.net/10962/d1006508
- Description: A new simple, precise and accurate high performance liquid chromatography (HPLC) method was developed and validated for the simultaneous determination of irinotecan (CPT-11) and two related compounds viz., 7-ethyl-10 hydroxycamptothecin (SN-38) and camptothecin (CPT) in pharmaceutical dosage forms. Chromatography was accomplished using a reversed-phase C18 column and ultraviolet (UV)detection and an isocratic mobile phase consisting of 3 % v/v triethylammonium acetate buffer (pH 3) and acetonitrile (70:30 v/v). The linear range of quantitation for all the compounds was 0.1-10 μg/mL. The limit of quantitation for all the compounds ranged between 0.01-0.05 μg/mL. The method has the requisite accuracy, selectivity, sensitivity and precision to assay of CPT-11 and related compounds in pharmaceutical dosage forms and bulk API.
- Full Text:
- Date Issued: 2010
- Authors: Mohammadi, Ali , Esmaeili, Farnaz , Dinarvand, Rassoul , Atyabi, Fatemeh , Walker, Roderick B
- Date: 2010
- Language: English
- Type: Article
- Identifier: vital:6413 , http://hdl.handle.net/10962/d1006508
- Description: A new simple, precise and accurate high performance liquid chromatography (HPLC) method was developed and validated for the simultaneous determination of irinotecan (CPT-11) and two related compounds viz., 7-ethyl-10 hydroxycamptothecin (SN-38) and camptothecin (CPT) in pharmaceutical dosage forms. Chromatography was accomplished using a reversed-phase C18 column and ultraviolet (UV)detection and an isocratic mobile phase consisting of 3 % v/v triethylammonium acetate buffer (pH 3) and acetonitrile (70:30 v/v). The linear range of quantitation for all the compounds was 0.1-10 μg/mL. The limit of quantitation for all the compounds ranged between 0.01-0.05 μg/mL. The method has the requisite accuracy, selectivity, sensitivity and precision to assay of CPT-11 and related compounds in pharmaceutical dosage forms and bulk API.
- Full Text:
- Date Issued: 2010
Sunday Times: Celebrating Women
- Authors: Sunday Times
- Date: 2010
- Subjects: Nyokong, Tebello
- Language: English
- Type: Article , text
- Identifier: vital:7187 , http://hdl.handle.net/10962/d1006279 , Nyokong, Tebello
- Description: A passion for light drove Professor Tebello Nyokong of Rhodes University into her photodynamic therapy research, harnessing light for cancer therapy and environmental clean-up using special dyes. And with this groundbreaking work she won the Africa-Arab State 2009 L'Oreal UNESCO Award for Women in Science.
- Full Text:
- Date Issued: 2010
- Authors: Sunday Times
- Date: 2010
- Subjects: Nyokong, Tebello
- Language: English
- Type: Article , text
- Identifier: vital:7187 , http://hdl.handle.net/10962/d1006279 , Nyokong, Tebello
- Description: A passion for light drove Professor Tebello Nyokong of Rhodes University into her photodynamic therapy research, harnessing light for cancer therapy and environmental clean-up using special dyes. And with this groundbreaking work she won the Africa-Arab State 2009 L'Oreal UNESCO Award for Women in Science.
- Full Text:
- Date Issued: 2010