Detriments associated with substance abuse among out - of - school youth in Ntselamanzi, village, Alice Town
- Authors: Chatikobo, Nyasha
- Date: 2015
- Subjects: Substance abuse--South Africa--Eastern Cape , Drug abuse--South Africa--Eastern Cape , Youth--Substance use--South Africa--Eastern Cape
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/19442 , vital:43087
- Description: The main aim of the study was to investigate the detriments associated with substance abuse among the out- of- school youth of Ntselamanzi Village in Alice. This study intended to achieve the following objectives. (i) to establish the causes of increased indulgence in substance abuse in Ntselamanzi village, Eastern Cape. (ii) to identify the various kinds of drugs abused by the society of Ntselamanzi (iii) to identify the consequences of substance abuse to the lives of the out-of-school youth. (iv) to suggest the strategies that can be used to reduce substance abuse in order to enhance the youth‟s socio-economic growth and societal bliss. Using the quantitative method ninety-eight questionnaires were administered to the out-of-school youth in Ntselamanzi village and eighty questionnaires were returned fully answered. The major findings of the study outlined that dominating factors of substance abuse in Ntselamanzi village were family drug use, increased drug accessibility, lack of recreation and peer influence. As a result drug abuse among the out of school youth has indicated that the youth end up dropping out of school, unemployed, facing health complications and committing anti-social activities in the village which causing family conflicts and rifts in the community. These all affected the out-of-school youths‟ well-being, academic future and their quality of life was lowered due to all related issues with drug abuse. It can be concluded that drug use among rural outof-school youth is detrimental to the out-of-school youths, their families destroyed and their community crippled from the anti-social activities that take place. The future of the youths‟ education is hampered; the quality of persons in the community and families is lowered. Having unproductive out-of-school youth as a result of drug abuse is not good for the development of the village and all the persons therein. , Thesis (M Soc Sc) (Social Work) -- University of Fort Hare, 2015
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- Date Issued: 2015
Educators and learners perceptions on english first additional language speakers use of english as medium of instruction
- Authors: Nqoma, Lungiswa
- Date: 2015
- Subjects: English language -- Study and teaching , English language
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/24934 , vital:63678
- Description: This study investigates Educators‟ and learners‟ perceptions on English first additional language speakers‟ use of English as medium of instruction in two primary schools in the East London District. The study made use of a qualitative research method which includes interviews, observation and document analysis (learners‟ books). The uncovered data is analyzed against the background of the socio-economic and historical factors that led to this medium of instruction using content analysis (CA). After the apartheid regime in 1994 and the formation of a new government in 1996, the South African Constitution declared 11 languages in an attempt to encourage multilingualism in the country with each province having its provincial language policy. In the Eastern Cape where the study is conducted the language policy recognizes Xhosa, English, and Afrikaans as the official languages with English as the medium of instruction especially at the intermediate phase. The theoretical and conceptual framework for the study is provided by studies on language policy and planning, English as an international language, and Language as a mediating tool. The findings of the study indicate the crucial role that language of instruction plays in teaching and learning. However, challenges arise when the language of instruction is not the mother tongue. The study indicates dissatisfaction in the use of EMOI as a result of inadequate proficiency in the language of instruction, school environment, lack of resources; and lack of parental support. As a result of the above, some educators resorted to code switching when teaching. Hence, the study sheds light on EFAL learner‟s perspective on both comprehension and the level of educator‟s English skills and whether there is a connection between these two aspects. This resulted to conceivable methods that could be used to improve learner performance, teaching and learning methods and the efficiency of East London District support system. , Thesis (MEd) -- Faculty of Education, 2015
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- Date Issued: 2015
Evaluation of knowledge and practices of nurses with regard to prevention of nosocomial infection in the intensive care units of Eastern Cape Province
- Authors: Mlenzana, Nosiphiwo Priscilla
- Date: 2015
- Subjects: Nosocomial infections http://id.loc.gov/authorities/subjects/sh85092770 , Cross infection--Prevention http://id.loc.gov/authorities/subjects/sh2009122612 , Infection http://id.loc.gov/authorities/subjects/sh85066076
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/19639 , vital:43154
- Description: Aim: To determine the level of knowledge and practice of the nurses in the prevention and control of nosocomial infection in the intensive care units and make recommendations aiming at bridging the gap identified. In this study, the level of knowledge and practice of nurses in the intensive care units was described and its relationship with the demographic characteristics was examined utilising a quantitative approach. A quantitative descriptive design was used to examine and describe knowledge and practices of intensive care nurses with regards to prevention and control of nosocomial infection. One hundred and thirty (130) nurses participated in the study taken from the intensive care units of the five (5) state hospitals of the Eastern Cape Province. A self-designed questionnaire with close-ended questions was utilised comprising of dichotomous questions, with ‘yes’ or ‘no’ measuring knowledge nurses have and a Likert scale that measured knowledge with regards to clinical practice utilised in the prevention and control of nosocomial infections. The following ethical considerations were addressed by the study: ethical clearance, permission to conduct the study, informed consent from participants, anonymity and confidentiality and respect of individual autonomy. Findings: The respondents showed encouraging agreement with the different practices that should be followed in order to prevent spreading of nosocomial infections in their units. This knowledge suggests that the problem of infection control in ICUs may be related to the individual characteristics of the profession as opposed to being institutional. Limitations: Not all the intensive care units of the Eastern Cape hospitals were included due to challenges of time, finance and geographic factors. Recommendations: The following recommendations were made: Orientation programme to all new staff coming into the ICUs including infection control policies and guidelines; Involvement of the ICU staff in the development of infection control policies so as to ensure ownership and ultimate compliance; The employer must ensure that all resources for infection control and prevention are available and accessible to the health care workers at all times to ensure compliance. , Thesis (MCur) -- University of Fort Hare, 2015
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- Date Issued: 2015
Evaluation of selected non- governmental organizations (NGOs) in the provision of health , education & housing services in South Africa the study of Alice township Eastern cape province
- Authors: Kajiita, Robert Mutemi https://orcid.org/0000-0003-2829-4824
- Date: 2015
- Subjects: Non-governmental organizations http://id.loc.gov/authorities/subjects/sh86007360 , Sustainable development--South Africa http://id.loc.gov/authorities/subjects/sh2010115191
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/19567 , vital:43144
- Description: The dynamism of human needs and the inability of the state and governments to guarantee a satisfactory access to, as well as consumption of private and public goods and services have prompted an up-sprung of alternative institutions such as the Non-Governmental Organizations. This study sought to evaluate selected NGOs in provision of health, education and housing services in Alice Township of the Eastern Cape Province. The study had the following specific objectives: to evaluate the role of selected NGOs in Alice in the provision of health, education and housing services; to examine the successes and possible gaps of selected NGOs in provision of aforementioned services; to examine the relationship between the NGOs and the government in provision of above mentioned services; and finally to establish the strategies that can be adopted to enhance NGOs’ capabilities in services delivery. To achieve these objectives, the study utilized mixed methods research approach, with an explorative and a mini-survey design. Non-probability sampling methodology was used and specifically purposive sampling was used to get a sample of 115 research participants and respondents. Data collection was cross- sectional and was facilitated by the use of in-depth interviews using semi-structured interviews and questionnaires. Data was analysed using both qualitative and quantitative approaches, and the results were triangulated to answer the research problem. The study was premised on the Public-Private Partnership (PPP) model of service delivery, and diverse literature was sought to strengthen the findings. The study revealed that: the females were more active in welfare sector than men; the concept NGO posed a conceptual challenge to the research participants; high level of unemployment and low level of tertiary literacy among study participants was reported. Furthermore, NGOs in Alice provided health based services which included creating awareness, control and treatment of communicable and non-communicable diseases such as HIV/AIDS, tuberculosis, diabetes, psychological and palliative care, counselling and old age care services. Educationally, early childhood development services took the lion’s share. This is evidenced by an array of day care centres in Alice. Regrettably, there were no housing services offered by NGOs in the area. The findings also revealed diametrically opposed debates on successes of NGOs in Alice, with some not seeing the success while others indicated some successful milestones. Notably, the NGOs in Alice suffered a paucity of resources which included: lack of funds, unskilled and inadequate staff, infrastructural and technological challenges, lack of transport facilities among others. The study also indicated a sour relationship between the government and the NGOs. Despite this, the NGOs were reported to adhere largely to the policy guidelines postulated by the government. Moreover, the government was the major funder of the most NGOs in the area of study. The findings revealed that fundraising skills were needed to bolster the NGOs financial muscle towards the achievement of project implementation. The state of infrastructure also needed to be addressed as well as scaling up the NGOs services to reach to a greater section of the society, Partnerships, collaborations and networking for NGOs would enable NGOs services delivery. The study also recommended: inclusivity in the welfare sector, establishment of vibrant housing NGOs in Alice, empowerment approaches to service provisioning, proper visibility of the NGOs in the community, systematic and regular promotion of training among the NGOs’ staff, sound and up to date harmonised policies, mutually designed partnerships, collaborations and networks, flexibility of donor funding approaches, intensive and extensive government support to NGOs, periodic scientific inquiry on NGOs operations and finally recommendation is made for further research in the area under the study. Conclusively, it is critical that NGOs in Alice are doing their best compared to their resource base and therefore, the government should study the environment of the NGOs in the area with the hope of coming up with plausible and pragmatic ways of bolstering their operations. , Thesis (M Soc Sc)(Social work) -- University of Fort Hare, 2015
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- Date Issued: 2015
Human FN1 is regulated by the heat-shock response
- Authors: Dhanani, Karim Colin Hassan
- Date: 2015
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193487 , vital:45336
- Description: Heat shock protein 90 (Hsp90) and heat shock factors (HSFs) are known to be involved in the epigenetic regulation of several fundamental oncogenic genes. Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein which plays key roles in cell adhesion and migration. Hsp90 binds directly to FN and Hsp90 inhibition has been shown to regulate FN protein levels and matrix formation. Where inhibition of Hsp90 with a C-terminal inhibitor (novobiocin) induced the loss of FN matrix, treatment with an N-terminal inhibitor (geldanamycin) increased FN matrix levels. GA treatment induced a strong dose and time dependent increase in FN1 promoter activity and increased total FN mRNA respectively. By contrast, NOV showed no increase in the promoter activity and no change in the expression of FN mRNA. As GA is known to induce the stress response, we investigated the relationship between the cell stress machinery and the transcriptional regulation of FN. Three putative heat shock elements (HSEs) were identified in the FN1 promoter. The loss of two of the three identified putative HSEs resulted in a loss in the basal transcriptional activity of the FN1 promoter in our reporter model. This was in addition to the loss of the induction of transcriptional activity with GA treatment observed with the full-length promoter. Binding of HSF1 to one of the putative HSEs, which was identified as potentially functional from the truncation analysis, was confirmed using ChIP. The occupancy of this HSE by HSF1 was shown to increase with GA treatment. These data support the hypothesis that FN1 is a functional HSF1 target gene. The 5' promoter regions of seven additional ECM protein encoding genes were analysed and mRNA levels were detected by quantitative RT-PCR upon treatment with GA. Collagen 4 _2 and laminin _3 mRNA were found to increase in the presence of GA, whereas collagen 4 _3 and osteopontin showed no change. Similarly to FN1, these data indicate that a subset of ECM genes may be under the regulation of the HSF1 mediated heat-shock response. This may have implications for our understanding of ECM dynamics in cancer, where the clinical application of Hsp90 inhibitors is intended. Additionally, our data provide a poten- tial underpinning for the role of the HSF1 mediated heat-shock response in several fibrotic and metabolic stress related pathologies. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2015
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- Date Issued: 2015
If I Stay Right Here
- Authors: Ngamlana, Chwayita
- Date: 2015
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193498 , vital:45337
- Description: My novella concerns the dynamics of a relationship between two girls. It shows the heterosexual‐like nature of the relationship rather than dwelling on the pressures on lesbians from society as a whole. At its core is the raw emotion and passion of the relationship, which is at the same time toxic, destructive and volatile because of their class differences and other insecurities. The work is influenced by the grit, openness, and innovation of several contemporary writers. , Thesis (MA) -- Faculty of Humanities, Institute for the Study of English in Africa, 2015
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- Date Issued: 2015
Managing the procurement of learner teacher support material (LTSM) in the Eastern Cape Department of Education
- Authors: Gobe, Mziwamadoda Chumasande
- Date: 2015
- Subjects: Government purchasing , Industrial procurement -- Management
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/24846 , vital:63616
- Description: The use of learner teacher support material (LTSM) was introduced with the aim of improve the education quality in South Africa. However, the procurement of the learner teacher support material has had several challenges. The study therefore was aimed at assessing the management of the procurement of LTSM in the Eastern Cape which is done by the Eastern Cape Department of Education. The aims of the study therefore were, to provide a full description of the current supply chain management practices of the ECDOE, examine the strengths and weaknesses of the current procurement management model in the acquisition of LTSM and investigate alternative selection, delivery and management models. To attain these aims data was collected using both the quantitative and qualitative methods. The use of the two methods helped to establish a balance in collecting data as the research sought to use both quantitative and qualitative data. The research used a case study design.The research instruments that were used to collected data were questionnaires and semi-structured interviews. The data for the study was provided by school principals, district officials and ECDoE officials. These were the best participants for the study as they have information on the current procurement system. The data was analysed in themes. The data was presented and discussed in relation to other studies that have been conducted on similar topics. The study found that the current procurement system is flawed due to several reasons like lack of clarity on roles and responsibilities, training and other factors discussed in the study. The study also found that there are inherent strengths and weaknesses in the current procurement model. The study found that the weaknesses can be addressed. The study also found that improvements and alternatives are possible for procurement. The study suggested several recommendations. Some of the recommendations include training the current staff involved in the supply chain management of the procurement system. The other being clarifying the roles and responsibilities of the stakeholders involved in the procurement process. , Thesis (MPA) -- Faculty of Management and Commerce. 2015
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- Date Issued: 2015
The impact of unguided animal husbandry on the peripheral and landscape elements: the case of Alice
- Authors: Chungag, Anye https://orcid.org/0000-0002-2308-9410
- Date: 2015
- Subjects: Livestock , Animal culture , Animal culture -- South Africa -- Eastern Cape
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/19511 , vital:43134
- Description: This study is based on Unguided Animal Husbandry as practiced in the town of Alice and its surrounding locations. It underscores the fact that though cattle are domesticated animals, they are still migratory in character. Their migratory tendency is prompted by the need of food and water and sometimes convenient rest positions. The search for food, water and rest may lead cattle to travel for many kilometres away from enclosure. This movement allows them to establish eating and drinking preferences and locations which become habitual, hence tracks develop along these paths which greatly compromise the soil, water and vegetation quality of the landscape. This study identifies such tracks and investigates the impact of cattle movement on soil physical properties and vegetation characteristics. However all this is against the back drop of the open access land regime; a mode of exploiting common property to which all have equal rights. It is a system of land management that comes with inherent challenges. Amongst them a selfish inclination of taking decisions that is motivated by egoistic interests and utmost personal gain. Secondly no thought is given to management and sustainability, subjecting common property to Haddins (1968) philosophy ‘The tragedy of the commons’. The results of the study show that when cattle is left to free range in common property they establish feeding, drinking and rest habits that have greater negative consequences on ecosystem elements of soil, vegetation and water than the positive effects they bring. The open access regime under which this farming system operates is appraised and recommendations proposed for its amelioration. , Thesis (MPhil) (Environmental Studies) -- University of Fort Hare, 2015
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- Date Issued: 2015
The reform of world order?: BRICS in an Interpolar world
- Authors: Phyllis, Yvonne
- Date: 2015
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193520 , vital:45339
- Description: International relations has recently seen new developments which are unpredictable and in their infant stage. The causes of these developments are plentiful, the consequences stemming from waning unipolarity to the emergence of new fora creating their own spaces. Whatever the case, international relations is not as it was in the period just after the Cold War. As a result, the terms of global governance established after 1990 have come under serious scrutiny. This transition has the makings of a new world order, an interpolar world order. This study asserts that we no longer live in a unipolar world, nor do we live in a world which can only be described as multipolar. It makes the argument that although multipolarity is a crucial element of the world, it only offers a partial description of today’s order. The study asserts that it is interpolarity which is closest in accounting for today’s world. Not only does it describe the world as multipolar, it also describes it as interdependent. To this end, the study provides a detailed account of what is meant by an interpolar world order and how differently it explains international events. It also provides an account of factors which can develop in an interpolar world. One of these includes allowing room for emerging powers to create their own spaces in efforts of avoiding co-option while continuing to realise the importance of operating within a context of continuity. This means that emerging countries create their own spaces but they also realise the importance of working with already established regimes such as the G20. BRICS (Brazil, Russia, India, China and South Africa) is used as a case study to indicate one of the new developments afforded by an interpolar order-the emergence of new fora. The study asserts that although BRICS is rife with internal dissimilarities, it has indicated some degree of political will in one aspect; that is; advocating for the reform of the terms of global governance, advocating for more representative forms of global governance. The study thus explores factors of a world whose contours are gradually changing but which are unpredictable and in flux. , Thesis (MA) -- Faculty of Humanities, Political and International Studies, 2015
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- Date Issued: 2015
The role of Stress Inducible Protein 1 (STI1) in the regulation of actin dynamics
- Authors: Beckley, Samantha Joy
- Date: 2015
- Subjects: Heat shock proteins , Molecular chaperones , Actin , Microfilament proteins , Cell migration , Adenosine triphosphatase , Metastasis
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/193941 , vital:45409
- Description: Stress-inducible protein 1 (STI1) otherwise known as Hop (Hsp70/Hsp90 organising protein) is a highly conserved abundant co-chaperone of the Hsp70 and Hsp90 chaperones. STI1 acts as an adapter protein, where it regulates the transfer of protein substrates from Hsp70 to Hsp90 during the assembly of a number of chaperone-client protein complexes. The role of STI1 associating independently with non-chaperone proteins has become increasingly prominent. Recent data from colocalisation and co-sedimentation analyses in our laboratory suggested a direct interaction between STI1 and the cytoskeletal protein, actin. However, there was a lack of information on the motifs which mediated this interaction, as well as the exact role of STI1 in the regulation of cytoskeletal dynamics. Two putative actin binding motifs, DAYKKK (within the TPR2A domain) and a polyproline region (after the DP1 domain), were identified in mammalian STI1. Our data from in vitro interaction studies including surface plasmon resonance and high speed co-sedimentation assays suggested that both TPR1 and TPR2AB were required for the STI1-actin interaction, and peptides corresponding to either the DAYKKK or the polyproline motif, alone or in combination, could not block the STI1-actin interaction. Full length mSTI1 was shown to have ATPase activity and when combined with actin an increase in ATPase activity was seen. Ex vivo studies using STI1 knockdown shRNA HEK293T cells and non-targeting control shRNA HEK293T cells showed a change of F-actin morphology as well as reduction in levels of actin-binding proteins profilin, cofilin and tubulin in the STI1 knockdown cells. These data extend our understanding of the role of STI1 in regulating actin dynamics and may have implications for cell migration. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2015
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- Date Issued: 2015
Using GIS and remote sensing to map suitable sites for wind farms: a case study of Nkonkobe Municipality, Eastern Cape.
- Authors: Gwena, Jay
- Date: 2015
- Subjects: Geographic information systems http://id.loc.gov/authorities/subjects/sh90001880 , Remote sensing http://id.loc.gov/authorities/subjects/sh85112798 , Renewable energy sources http://id.loc.gov/authorities/subjects/sh85112837
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/19420 , vital:43082
- Description: Issues relating to energy use, renewable energy introduction and climate change have received a lot of attention from governments throughout the world in the past two decades. Many developing nations like South Africa heavily rely on coal and other non-renewable resources for their production of energy. The processing of the non-renewable resources into secondary energy forms is according to many energy experts a chief contributor to climate change. Climate change is affecting agricultural production in many developing countries that entirely rely on rainfall for their production. The loss in production in South Africa is increasing the level of poverty in low-income earners and unemployed people. Also a lot of households found in rural areas of South Africa have no access to electricity. Electricity in South Africa is generated and distributed by Eskom a state owned company. In April 2008 Eskom failed to meet power demand and started introducing load shedding to maintain and upgrade their power plants. The load shedding stopped for while and was introduced again in 2014 when the power utility faced the challenge of failing to produce power to meet demand again due to problems with their power stations. The ongoing energy provision problems in South Africa can be alleviated by introducing alternative sources like renewable energy. Introduction of renewable energy in poorly developed areas like Nkonkobe Municipality can help households‘ access electricity and reduce load on the national grid. The aim of this study was to locate suitable sites for setting up wind farms in Nkonkobe municipality in South Africa. Wind energy as a resource is abundant in many areas of South Africa and areas to set wind farms for optimum harness of wind power were identified using GIS, remote sensing and multi-criteria decision making techniques. Wind speed, distance from settlements, distance from main roads, distance from national, slope and land use/land cover were chosen as the factors to consider in selecting a suitable site. Data was collected from South Africa Weather Services, University of Fort Hare and online free data sources. Thematic maps for all the factors were developed in ArcGIS and fed into Nkonkobe Municipality database developed for the study. Thematic maps were assigned weights before being overlaid using weighted overlay tool. Weights for the factors were determined using Analytical hierarchy Process‘ pairwise comparison approach. Weighted overlay of the thematic maps produced a map showing suitable areas based on the weight influence of each factor. The output map was compared to results obtained from using Boolean approach and weighted sum method as a way of checking the accuracy of obtained suitable sites. Results showed there are three sites that can be used for setting up wind farms in the study area. , Thesis (MSc) (Applied Remote Sensing and GIS) -- University of Fort Hare, 2015
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- Date Issued: 2015