Can Jamaica put music first?: a comment
- Authors: Stanley Niaah, Sonjah
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145941 , vital:38480 , https://0-doi.org.wam.seals.ac.za/10.1080/00086495.2018.1480319
- Description: Many development programmes fail because they don’t account for cultural contexts. In a context where cultural and creative industries represent 10% of the GNP in economies such as Brazil, China, India, and Indonesia, there is no doubt that culture is vital for their sustainable development.
- Full Text:
- Authors: Stanley Niaah, Sonjah
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145941 , vital:38480 , https://0-doi.org.wam.seals.ac.za/10.1080/00086495.2018.1480319
- Description: Many development programmes fail because they don’t account for cultural contexts. In a context where cultural and creative industries represent 10% of the GNP in economies such as Brazil, China, India, and Indonesia, there is no doubt that culture is vital for their sustainable development.
- Full Text:
Capturing the Soweto Uprising: South Africa’s most iconic photograph lives on
- Authors: Simbao, Ruth K
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147036 , vital:38587 , https://theconversation.com/capturing-the-soweto-uprising-south-africas-most-iconic-photograph-lives-on-98318
- Description: Sam Nzima, the photographer who captured the iconic image of the 1976 Soweto Uprising passed awayon May 12, 2018. The photograph was one of six frames showing Mbuyisa Makhubu carrying 12-year-old Hector Pieterson who was shot by police, and Hector’s sister, Antionette Pieterson (now Sithole) running alongside.
- Full Text:
- Authors: Simbao, Ruth K
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147036 , vital:38587 , https://theconversation.com/capturing-the-soweto-uprising-south-africas-most-iconic-photograph-lives-on-98318
- Description: Sam Nzima, the photographer who captured the iconic image of the 1976 Soweto Uprising passed awayon May 12, 2018. The photograph was one of six frames showing Mbuyisa Makhubu carrying 12-year-old Hector Pieterson who was shot by police, and Hector’s sister, Antionette Pieterson (now Sithole) running alongside.
- Full Text:
Challenges and curriculum transformation in the higher education sector in South Africa: a case study in WASH to improve the training of pharmacists
- Tandlich, Roman, Ngqwala, Nosiphiwe P, Boshoff, Aileen, Madikizela, Phindile, Srinivas, Sunitha C, Pyle, Desmond M, Oosthuizen, Rene
- Authors: Tandlich, Roman , Ngqwala, Nosiphiwe P , Boshoff, Aileen , Madikizela, Phindile , Srinivas, Sunitha C , Pyle, Desmond M , Oosthuizen, Rene
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/76858 , vital:30631 , https://doi.org/10.2478/atd-2018-0001
- Description: South Africa is a member state of the “BRICS” bloc (BRICS2017.org, 2017) and the G20 group of the 20 nations/economic blocs, which between them account for the majority of the world’s trade and economic activity. It faces many developmental challenges which are mirrored in its higher education sector. In this article, the authors seek to provide an overview of the challenges that South African higher education faces in the achievement of the developmental goals of the country. The focus of this paper is a case study in WASH (water, sanitation and hygiene) to improve context-specific responses that trains pharmacists on knowledge and skills.
- Full Text:
- Authors: Tandlich, Roman , Ngqwala, Nosiphiwe P , Boshoff, Aileen , Madikizela, Phindile , Srinivas, Sunitha C , Pyle, Desmond M , Oosthuizen, Rene
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/76858 , vital:30631 , https://doi.org/10.2478/atd-2018-0001
- Description: South Africa is a member state of the “BRICS” bloc (BRICS2017.org, 2017) and the G20 group of the 20 nations/economic blocs, which between them account for the majority of the world’s trade and economic activity. It faces many developmental challenges which are mirrored in its higher education sector. In this article, the authors seek to provide an overview of the challenges that South African higher education faces in the achievement of the developmental goals of the country. The focus of this paper is a case study in WASH (water, sanitation and hygiene) to improve context-specific responses that trains pharmacists on knowledge and skills.
- Full Text:
Characterization and computational studies of a co-crystal of 2-aminobenzimidazole and 2-[(benzoylcarbamothioyl) amino] propanoic acid
- Odame, Felix, Hosten, Eric C, Betz, Richard, Lobb, Kevin A, Tshentu, Zenixole R
- Authors: Odame, Felix , Hosten, Eric C , Betz, Richard , Lobb, Kevin A , Tshentu, Zenixole R
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/447030 , vital:74578 , xlink:href="https://doi.org/10.1134/S0022476618050268"
- Description: A novel co-crystal of 2-aminobenzimidazole and 2-[(benzoylcarbamothioyl)amino] propanoic acid is synthesized and characterized by spectroscopy, elemental analysis, GC-MS, and single crystal XRD. A computation of the structures involved in the formation of the co-crystal are carried out and their contribution to reactivity is explained.
- Full Text:
- Authors: Odame, Felix , Hosten, Eric C , Betz, Richard , Lobb, Kevin A , Tshentu, Zenixole R
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/447030 , vital:74578 , xlink:href="https://doi.org/10.1134/S0022476618050268"
- Description: A novel co-crystal of 2-aminobenzimidazole and 2-[(benzoylcarbamothioyl)amino] propanoic acid is synthesized and characterized by spectroscopy, elemental analysis, GC-MS, and single crystal XRD. A computation of the structures involved in the formation of the co-crystal are carried out and their contribution to reactivity is explained.
- Full Text:
Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics:
- Amamuddy, Olivier S, Bishop, Nigel T, Tastan Bishop, Özlem
- Authors: Amamuddy, Olivier S , Bishop, Nigel T , Tastan Bishop, Özlem
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148126 , vital:38712 , DOI: 10.1038/s41598-018-36041-8
- Description: The use of antiretrovirals (ARVs) has drastically improved the life quality and expectancy of HIV patients since their introduction in health care. Several millions are still afflicted worldwide by HIV and ARV resistance is a constant concern for both healthcare practitioners and patients, as while treatment options are finite, the virus constantly adapts via complex mutation patterns to select for resistant strains under the pressure of drug treatment. The HIV protease is a crucial enzyme for viral maturation and has been a game changing drug target since the first application. Due to similarities in protease inhibitor designs, drug cross-resistance is not uncommon across ARVs of the same class.
- Full Text:
- Authors: Amamuddy, Olivier S , Bishop, Nigel T , Tastan Bishop, Özlem
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148126 , vital:38712 , DOI: 10.1038/s41598-018-36041-8
- Description: The use of antiretrovirals (ARVs) has drastically improved the life quality and expectancy of HIV patients since their introduction in health care. Several millions are still afflicted worldwide by HIV and ARV resistance is a constant concern for both healthcare practitioners and patients, as while treatment options are finite, the virus constantly adapts via complex mutation patterns to select for resistant strains under the pressure of drug treatment. The HIV protease is a crucial enzyme for viral maturation and has been a game changing drug target since the first application. Due to similarities in protease inhibitor designs, drug cross-resistance is not uncommon across ARVs of the same class.
- Full Text:
Click chemistry electrode modification using 4-ethynylbenzyl substituted cobalt phthalocyanine for applications in electrocatalysis
- Mpeta, Lekhetho S, Fomo, Gertrude, Nyokong, Tebello
- Authors: Mpeta, Lekhetho S , Fomo, Gertrude , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187626 , vital:44681 , xlink:href="• https://doi.org/10.1080/00958972.2018.1466118"
- Description: In this work, we report on the synthesis and applications of a new cobalt tetrakis 4-((4-ethynylbenzyl) oxy) phthalocyanine (3) for the detection of hydrazine. The glassy carbon electrode (GCE) was first grafted through diazotization, providing the GCE surface layer with azide groups. Thereafter, the 1,3-dipolar cycloaddition reaction, catalyzed by a copper(I) catalyst was used to “click” complex 3 to the grafted surface of GCE. The new platform was then characterized using cyclic voltammetry (CV), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). This work shows that 3 is an effective sensor with sensitivity of 91.5 μA mM−1 and limit of detection of 3.28 μM which is a great improvement compared to other reported sensors for this analyte.
- Full Text:
- Authors: Mpeta, Lekhetho S , Fomo, Gertrude , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187626 , vital:44681 , xlink:href="• https://doi.org/10.1080/00958972.2018.1466118"
- Description: In this work, we report on the synthesis and applications of a new cobalt tetrakis 4-((4-ethynylbenzyl) oxy) phthalocyanine (3) for the detection of hydrazine. The glassy carbon electrode (GCE) was first grafted through diazotization, providing the GCE surface layer with azide groups. Thereafter, the 1,3-dipolar cycloaddition reaction, catalyzed by a copper(I) catalyst was used to “click” complex 3 to the grafted surface of GCE. The new platform was then characterized using cyclic voltammetry (CV), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). This work shows that 3 is an effective sensor with sensitivity of 91.5 μA mM−1 and limit of detection of 3.28 μM which is a great improvement compared to other reported sensors for this analyte.
- Full Text:
Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide-based inhibitor design:
- Musyoka, Thommas M, Njuguna, Joyce N, Tastan Bishop, Özlem
- Authors: Musyoka, Thommas M , Njuguna, Joyce N , Tastan Bishop, Özlem
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148392 , vital:38735 , DOI: 10.1101/381566
- Description: Falcipains are major cysteine proteases of Plasmodium falciparum involved in haemoglobin degradation and remain attractive anti-malarial drug targets. Several inhibitors against these proteases have been identified, yet none of them has been approved for malaria treatment. Other Plasmodium species also possess highly homologous proteins to falcipains. For selective therapeutic targeting, identification of sequence and structure differences with homologous human cathepsins is necessary. The substrate processing activity of these proteins is tightly controlled via a prodomain segment occluding the active site which is chopped under low pH conditions exposing the catalytic site. Current work characterizes these proteases to identify residues mediating the prodomain regulatory function for the design of peptide based anti-malarial inhibitors.
- Full Text:
- Authors: Musyoka, Thommas M , Njuguna, Joyce N , Tastan Bishop, Özlem
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/148392 , vital:38735 , DOI: 10.1101/381566
- Description: Falcipains are major cysteine proteases of Plasmodium falciparum involved in haemoglobin degradation and remain attractive anti-malarial drug targets. Several inhibitors against these proteases have been identified, yet none of them has been approved for malaria treatment. Other Plasmodium species also possess highly homologous proteins to falcipains. For selective therapeutic targeting, identification of sequence and structure differences with homologous human cathepsins is necessary. The substrate processing activity of these proteins is tightly controlled via a prodomain segment occluding the active site which is chopped under low pH conditions exposing the catalytic site. Current work characterizes these proteases to identify residues mediating the prodomain regulatory function for the design of peptide based anti-malarial inhibitors.
- Full Text:
Comparison of physiological responses to high temperatures in juvenile and adult Cape Rockjumpers Chaetops frenatus
- Oswald, Krista N, Lee, Alan T K, Smit, Ben
- Authors: Oswald, Krista N , Lee, Alan T K , Smit, Ben
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/441559 , vital:73898 , https://doi.org/10.2989/00306525.2018.1509905
- Description: Concerns about climate change have led to an increase in studies on physiological mechanisms birds possess to cope with increasing temperatures. For range-restricted species such as Cape Rockjumpers Chaetops frenatus, whose population declines are correlated with habitat warming, we identified juvenile physiological responses to high temperature as a potential gap in current knowledge. We compared metabolic rate, evaporative water loss, evaporative cooling efficiency (calculated from evaporative water loss and resting metabolic rate) and body temperature in juveniles (n = 5) with adult birds (n = 10) to a ramped temperature profile (30–42 °C). Although juveniles exhibited no significant difference in cooling efficiency, they had higher evaporative water loss, resting metabolic rate and body temperature. This suggests that while juvenile birds show similar abilities to dissipate metabolic heat evaporatively, they face higher overall water and energy demands, and thus higher thermoregulatory costs in maintaining body temperature as overall temperatures continue to increase.
- Full Text:
- Authors: Oswald, Krista N , Lee, Alan T K , Smit, Ben
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/441559 , vital:73898 , https://doi.org/10.2989/00306525.2018.1509905
- Description: Concerns about climate change have led to an increase in studies on physiological mechanisms birds possess to cope with increasing temperatures. For range-restricted species such as Cape Rockjumpers Chaetops frenatus, whose population declines are correlated with habitat warming, we identified juvenile physiological responses to high temperature as a potential gap in current knowledge. We compared metabolic rate, evaporative water loss, evaporative cooling efficiency (calculated from evaporative water loss and resting metabolic rate) and body temperature in juveniles (n = 5) with adult birds (n = 10) to a ramped temperature profile (30–42 °C). Although juveniles exhibited no significant difference in cooling efficiency, they had higher evaporative water loss, resting metabolic rate and body temperature. This suggests that while juvenile birds show similar abilities to dissipate metabolic heat evaporatively, they face higher overall water and energy demands, and thus higher thermoregulatory costs in maintaining body temperature as overall temperatures continue to increase.
- Full Text:
Comparison of physiological responses to high temperatures in juvenile and adult Cape Rockjumpers Chaetops frenatus
- Oswald, Krista N, Lee, Alan T K, Smit, Ben
- Authors: Oswald, Krista N , Lee, Alan T K , Smit, Ben
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448398 , vital:74727 , https://doi.org/10.2989/00306525.2018.1509905
- Description: Concerns about climate change have led to an increase in studies on physiological mechanisms birds possess to cope with increasing temperatures. For range-restricted species such as Cape Rockjumpers Chaetops frenatus, whose population declines are correlated with habitat warming, we identified juvenile physiological responses to high temperature as a potential gap in current knowledge. We compared metabolic rate, evaporative water loss, evaporative cooling efficiency (calculated from evaporative water loss and resting metabolic rate) and body temperature in juveniles (n = 5) with adult birds (n = 10) to a ramped temperature profile (30–42 °C). Although juveniles exhibited no significant difference in cooling efficiency, they had higher evaporative water loss, resting metabolic rate and body temperature. This suggests that while juvenile birds show similar abilities to dissipate metabolic heat evaporatively, they face higher overall water and energy demands, and thus higher thermoregulatory costs in maintaining body temperature as overall temperatures continue to increase.
- Full Text:
- Authors: Oswald, Krista N , Lee, Alan T K , Smit, Ben
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448398 , vital:74727 , https://doi.org/10.2989/00306525.2018.1509905
- Description: Concerns about climate change have led to an increase in studies on physiological mechanisms birds possess to cope with increasing temperatures. For range-restricted species such as Cape Rockjumpers Chaetops frenatus, whose population declines are correlated with habitat warming, we identified juvenile physiological responses to high temperature as a potential gap in current knowledge. We compared metabolic rate, evaporative water loss, evaporative cooling efficiency (calculated from evaporative water loss and resting metabolic rate) and body temperature in juveniles (n = 5) with adult birds (n = 10) to a ramped temperature profile (30–42 °C). Although juveniles exhibited no significant difference in cooling efficiency, they had higher evaporative water loss, resting metabolic rate and body temperature. This suggests that while juvenile birds show similar abilities to dissipate metabolic heat evaporatively, they face higher overall water and energy demands, and thus higher thermoregulatory costs in maintaining body temperature as overall temperatures continue to increase.
- Full Text:
Confronting the Colonial Library: teaching Political Studies amidst calls for a decolonised curriculum
- Authors: Matthews, Sally
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142191 , vital:38057 , DOI: 10.1080/02589346.2018.1418204
- Description: This paper engages with Mudimbe's concept of the ‘colonial library’ with the aim of using this engagement to contribute to current debates about decolonising South African university curricula. The term ‘colonial library’ refers to the body of texts and epistemological order which construct Africa as a symbol of otherness and inferiority. Mudimbe shows that even the most determined attempts to resist the colonial library draw on this same epistemological order. This presents a profound challenge for attempts to decolonise university curricula as it suggests that the colonial library's reach extends into attempts to dismantle it. In response to this challenge, I discuss ways in which we can oppose epistemological ethnocentrism and argue that we need to be open to the possibility of the emancipatory reappropriation of aspects of the colonial library. The paper concludes by relating the foregoing discussion to the South African political studies classroom.
- Full Text:
- Authors: Matthews, Sally
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/142191 , vital:38057 , DOI: 10.1080/02589346.2018.1418204
- Description: This paper engages with Mudimbe's concept of the ‘colonial library’ with the aim of using this engagement to contribute to current debates about decolonising South African university curricula. The term ‘colonial library’ refers to the body of texts and epistemological order which construct Africa as a symbol of otherness and inferiority. Mudimbe shows that even the most determined attempts to resist the colonial library draw on this same epistemological order. This presents a profound challenge for attempts to decolonise university curricula as it suggests that the colonial library's reach extends into attempts to dismantle it. In response to this challenge, I discuss ways in which we can oppose epistemological ethnocentrism and argue that we need to be open to the possibility of the emancipatory reappropriation of aspects of the colonial library. The paper concludes by relating the foregoing discussion to the South African political studies classroom.
- Full Text:
Conjugation of isoniazid to a zinc phthalocyanine via hydrazone linkage for pH-dependent liposomal controlled release
- Nkanga, Christian I, Krause, Rui W M
- Authors: Nkanga, Christian I , Krause, Rui W M
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/194992 , vital:45517 , xlink:href="https://doi.org/10.1007/s13204-018-0776-y"
- Description: Tuberculosis (TB) remains the leading cause of mortality from infectious diseases. Extended TB treatment and frequent adverse effects, due to poor bioavailability of anti-tubercular drugs (ATBDs), represent the main rationales behind liposomal encapsulation for controlled delivery. Liposomes have been reported as potential vehicles for targeted delivery of ATBDs due to their rapid uptake by macrophages, which are known as the main host cells for TB causative agent (Mycobacterium tuberculosis). Additionally, the need for controlled release of ATBDs arises because leakage is part of the key liposome challenges for hydrophilic compounds like isoniazid (INH). In this study, INH was conjugated to a highly hydrophobic photosensitizer, zinc (II) phthalocyanine (PC), through hydrazone bonding. The obtained conjugate (PC–INH) was encapsulated in liposomes by film hydration method. PC–INH loaded liposomes (PILs) were characterized using dynamic light scattering, transmission electron microscopy, energy-dispersive X-ray spectrometry and UV–Vis absorption spectrometry, which was used also for estimation of encapsulation efficiency (î). INH release was evaluated in different pH media using dialysis. Particle size, zeta potential and î of PILs were about 506 nm, − 55 mV and 72%, respectively. Over 12 h, PILs exhibited 22, 41, 97 and 100% of INH, respectively, released in pH 7.4, 6.4, 5.4 and 4.4 media. This pH-dependent behavior is attractive for site-specific delivery. These findings suggest the conjugation of chemotherapeutics to phthalocyanines using pH-labile linkages as a potential strategy for liposomal controlled release.
- Full Text:
- Authors: Nkanga, Christian I , Krause, Rui W M
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/194992 , vital:45517 , xlink:href="https://doi.org/10.1007/s13204-018-0776-y"
- Description: Tuberculosis (TB) remains the leading cause of mortality from infectious diseases. Extended TB treatment and frequent adverse effects, due to poor bioavailability of anti-tubercular drugs (ATBDs), represent the main rationales behind liposomal encapsulation for controlled delivery. Liposomes have been reported as potential vehicles for targeted delivery of ATBDs due to their rapid uptake by macrophages, which are known as the main host cells for TB causative agent (Mycobacterium tuberculosis). Additionally, the need for controlled release of ATBDs arises because leakage is part of the key liposome challenges for hydrophilic compounds like isoniazid (INH). In this study, INH was conjugated to a highly hydrophobic photosensitizer, zinc (II) phthalocyanine (PC), through hydrazone bonding. The obtained conjugate (PC–INH) was encapsulated in liposomes by film hydration method. PC–INH loaded liposomes (PILs) were characterized using dynamic light scattering, transmission electron microscopy, energy-dispersive X-ray spectrometry and UV–Vis absorption spectrometry, which was used also for estimation of encapsulation efficiency (î). INH release was evaluated in different pH media using dialysis. Particle size, zeta potential and î of PILs were about 506 nm, − 55 mV and 72%, respectively. Over 12 h, PILs exhibited 22, 41, 97 and 100% of INH, respectively, released in pH 7.4, 6.4, 5.4 and 4.4 media. This pH-dependent behavior is attractive for site-specific delivery. These findings suggest the conjugation of chemotherapeutics to phthalocyanines using pH-labile linkages as a potential strategy for liposomal controlled release.
- Full Text:
Conservation and human livelihoods at the crossroads: Local needs and knowledge in the management of Arabuko Sokoke Forest
- Chiawo, David O, Kombe, Wellington N, Craig, Adrian J F K
- Authors: Chiawo, David O , Kombe, Wellington N , Craig, Adrian J F K
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448843 , vital:74765 , https://doi.org/10.1111/aje.12462
- Description: Arabuko Sokoke Forest is the largest remaining single block of indigenous dry coastal tropical forest in Eastern Africa. Households within a 5 km buffer zone depend heavily on the forest for their livelihood needs, and the pressure on forest resources is on the increase. In May 2015, 109 households were interviewed on resources they obtain from the forest, in terms of the self‐reported level of monthly income. We found household income and farm size significantly positively correlated with benefits from the forest, highlighting the possible influence of household wealth in exploiting forest resources. A large proportion of households (32%) had limited knowledge of local birds, while human–bird conflict was reported by 44% of the households. While many households were keen to participate in conservation projects that maintain the forest, 44% had no knowledge of the forest management plan, and 60% of those interviewed had no idea of how forest zones were designated for particular activities. Drivers for local community participation in conservation projects appear to be sustainable income and fulfilment of basic household needs.
- Full Text:
- Authors: Chiawo, David O , Kombe, Wellington N , Craig, Adrian J F K
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448843 , vital:74765 , https://doi.org/10.1111/aje.12462
- Description: Arabuko Sokoke Forest is the largest remaining single block of indigenous dry coastal tropical forest in Eastern Africa. Households within a 5 km buffer zone depend heavily on the forest for their livelihood needs, and the pressure on forest resources is on the increase. In May 2015, 109 households were interviewed on resources they obtain from the forest, in terms of the self‐reported level of monthly income. We found household income and farm size significantly positively correlated with benefits from the forest, highlighting the possible influence of household wealth in exploiting forest resources. A large proportion of households (32%) had limited knowledge of local birds, while human–bird conflict was reported by 44% of the households. While many households were keen to participate in conservation projects that maintain the forest, 44% had no knowledge of the forest management plan, and 60% of those interviewed had no idea of how forest zones were designated for particular activities. Drivers for local community participation in conservation projects appear to be sustainable income and fulfilment of basic household needs.
- Full Text:
Contesting sexual violence policies in higher education: the case of Rhodes University
- Macleod, Catriona I, Böhmke, Werner, Barker, Kim, Mavuso, Jabulile M-J J, Chiweshe, Malvern T
- Authors: Macleod, Catriona I , Böhmke, Werner , Barker, Kim , Mavuso, Jabulile M-J J , Chiweshe, Malvern T
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/444275 , vital:74212 , xlink:href="https://www.emerald.com/insight/content/doi/10.1108/JACPR-05-2017-0295/full/html"
- Description: – In April 2016, students at Rhodes University brought the institution to a standstill as they protested the University’s sexual violence policies and procedures, as well as the “rape culture” that pervades social structures. In response, a Sexual Violence Task Team (SVTT) was formed in an open, participatory, and transparent process. Members of the University community were invited to comment on drafts of the SVTT document. The purpose of this paper is to outline the contestations – arising from both the establishment of the task team and the inputs from University members to drafts of the document – that surfaced concerning managing sexual violence on campuses and sexual offences policies.
- Full Text:
- Authors: Macleod, Catriona I , Böhmke, Werner , Barker, Kim , Mavuso, Jabulile M-J J , Chiweshe, Malvern T
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/444275 , vital:74212 , xlink:href="https://www.emerald.com/insight/content/doi/10.1108/JACPR-05-2017-0295/full/html"
- Description: – In April 2016, students at Rhodes University brought the institution to a standstill as they protested the University’s sexual violence policies and procedures, as well as the “rape culture” that pervades social structures. In response, a Sexual Violence Task Team (SVTT) was formed in an open, participatory, and transparent process. Members of the University community were invited to comment on drafts of the SVTT document. The purpose of this paper is to outline the contestations – arising from both the establishment of the task team and the inputs from University members to drafts of the document – that surfaced concerning managing sexual violence on campuses and sexual offences policies.
- Full Text:
Contrasting responses in the niches of two coral reef herbivores along a gradient of habitat disturbance in the Spermonde Archipelago, Indonesia
- Plass-Johnson, Jeremiah G, Bednarz, Vanessa N, Hill, Jaclyn M, Jompa, Jamaluddin, Ferse, Sebastian C A, Teichberg, Mirta
- Authors: Plass-Johnson, Jeremiah G , Bednarz, Vanessa N , Hill, Jaclyn M , Jompa, Jamaluddin , Ferse, Sebastian C A , Teichberg, Mirta
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69135 , vital:29398 , hhttps://doi.org/10.3389/fmars.2018.00032
- Description: Habitat modification of coral reefs is becoming increasingly common due to increases in coastal urban populations. Coral reef fish are highly dependent on benthic habitat; however, information on species-specific responses to habitat change, in particular with regard to trophic strategies, remains scarce. This study identifies variation in the trophic niches of two herbivorous coral reef fishes with contrasting trophic strategies, using Stable Isotopes Bayesian Ellipses in R, along a spatial gradient of changing coral reef habitats. In the parrotfish Chlorurus bleekeri, a roving consumer, the range of δ15N and δ13C and their niche area displayed significant relationships with the amount of rubble in the habitat. In contrast, the farming damselfish, Dischistodus prosopotaenia, showed a narrow range of both δ15N and δ13C, displaying little change in niche parameters among sites. This may indicate that parrotfish vary their feeding according to habitat, while the damselfish continue to maintain their turf and invertebrate resources. Assessing isotopic niches may help to better understand the specific trophic responses to change in the environment. Furthermore, the use of isotopic niches underlines the utility of stable isotopes in studying the potential impacts of environmental change on feeding ecology.
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- Authors: Plass-Johnson, Jeremiah G , Bednarz, Vanessa N , Hill, Jaclyn M , Jompa, Jamaluddin , Ferse, Sebastian C A , Teichberg, Mirta
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69135 , vital:29398 , hhttps://doi.org/10.3389/fmars.2018.00032
- Description: Habitat modification of coral reefs is becoming increasingly common due to increases in coastal urban populations. Coral reef fish are highly dependent on benthic habitat; however, information on species-specific responses to habitat change, in particular with regard to trophic strategies, remains scarce. This study identifies variation in the trophic niches of two herbivorous coral reef fishes with contrasting trophic strategies, using Stable Isotopes Bayesian Ellipses in R, along a spatial gradient of changing coral reef habitats. In the parrotfish Chlorurus bleekeri, a roving consumer, the range of δ15N and δ13C and their niche area displayed significant relationships with the amount of rubble in the habitat. In contrast, the farming damselfish, Dischistodus prosopotaenia, showed a narrow range of both δ15N and δ13C, displaying little change in niche parameters among sites. This may indicate that parrotfish vary their feeding according to habitat, while the damselfish continue to maintain their turf and invertebrate resources. Assessing isotopic niches may help to better understand the specific trophic responses to change in the environment. Furthermore, the use of isotopic niches underlines the utility of stable isotopes in studying the potential impacts of environmental change on feeding ecology.
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Control options for false codling moth, Thaumatotibia leucotreta (Lepidoptera: Tortricidae), in South Africa, with emphasis on the potential use of entomopathogenic nematodes and fungi
- Malan, Antoinette P, von Diest, J I, Moore, Sean D, Addison, Pia
- Authors: Malan, Antoinette P , von Diest, J I , Moore, Sean D , Addison, Pia
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/452219 , vital:75112 , https://hdl.handle.net/10520/EJC-de823b051
- Description: False codling moth (FCM), Thaumatotibia leucotreta (Lepidoptera: Tortricidae) is an important pest of various fruit crops in South Africa. Current FCM control strategies include the use of chemical insecticides. However, FCM has developed resistance to some of the insecticides, and stringent chemical residue restrictions have been imposed by some foreign markets. Thus, the demand for high-quality fruit has translated into a need for new, efficient and effective integrated pest management (IPM) strategies. One such strategy is the control of the soil-dwelling life stages of FCM, using entomopathogenic nematodes (EPNs) and entomopathogenic fungi (EPF). Both of the biocontrol agents concerned have individually been shown to be effective against FCM.
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- Authors: Malan, Antoinette P , von Diest, J I , Moore, Sean D , Addison, Pia
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/452219 , vital:75112 , https://hdl.handle.net/10520/EJC-de823b051
- Description: False codling moth (FCM), Thaumatotibia leucotreta (Lepidoptera: Tortricidae) is an important pest of various fruit crops in South Africa. Current FCM control strategies include the use of chemical insecticides. However, FCM has developed resistance to some of the insecticides, and stringent chemical residue restrictions have been imposed by some foreign markets. Thus, the demand for high-quality fruit has translated into a need for new, efficient and effective integrated pest management (IPM) strategies. One such strategy is the control of the soil-dwelling life stages of FCM, using entomopathogenic nematodes (EPNs) and entomopathogenic fungi (EPF). Both of the biocontrol agents concerned have individually been shown to be effective against FCM.
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Core-modified rubyrins with phenanthrene-fused pyrrole rings
- Yuan, Xuemei, Li, Minzhi, Meng, Ting, Mack, John, Soy, Rodah, Nyokong, Tebello, Zhu, Weihua, Xu, Haijun, Liang, Xu
- Authors: Yuan, Xuemei , Li, Minzhi , Meng, Ting , Mack, John , Soy, Rodah , Nyokong, Tebello , Zhu, Weihua , Xu, Haijun , Liang, Xu
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234568 , vital:50209 , xlink:href="https://doi.org/10.1016/j.dyepig.2018.05.045"
- Description: Three fused-ring-expanded rubyrins with modified macrocyclic core have been synthesized and characterized. A series of spectroscopic, electrochemical measurements and a set of theoretical calculations demonstrate that the core-modification of the inner core of rubyrins has a large influence on the electronic structure. Colorimetric changes are observe that demonstrate that these core-modified rubyrins could be used as selective Hg2+ ion sensors. These properties can be fine-tuned by introducing lipophilic substituents on the meso-aryl rings.
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- Authors: Yuan, Xuemei , Li, Minzhi , Meng, Ting , Mack, John , Soy, Rodah , Nyokong, Tebello , Zhu, Weihua , Xu, Haijun , Liang, Xu
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234568 , vital:50209 , xlink:href="https://doi.org/10.1016/j.dyepig.2018.05.045"
- Description: Three fused-ring-expanded rubyrins with modified macrocyclic core have been synthesized and characterized. A series of spectroscopic, electrochemical measurements and a set of theoretical calculations demonstrate that the core-modification of the inner core of rubyrins has a large influence on the electronic structure. Colorimetric changes are observe that demonstrate that these core-modified rubyrins could be used as selective Hg2+ ion sensors. These properties can be fine-tuned by introducing lipophilic substituents on the meso-aryl rings.
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Could differences in implicit attitudes to sexual concurrency play a role in generalized HIV epidemics?
- Kenyon, Chris R, Wolfs, Kenny, Osbak, Kara, van Hal, Guido, Zondo, Sizwe, van Lankveld, J
- Authors: Kenyon, Chris R , Wolfs, Kenny , Osbak, Kara , van Hal, Guido , Zondo, Sizwe , van Lankveld, J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/450574 , vital:74962 , xlink:href="10.12688/f1000research.14951.2"
- Description: Despite medical advances in Highly Active Antiretroviral Therapy (HAART), patients living with HIV continue to be at risk for developing HIV-associated neurocognitive disorders (HAND). The optimization of non-HAART interventions, including cognitive rehabilitation therapy (CRT), shows promise in reversing the impact of HAND. No data exist indicating the efficacy of CRT in remediating attention skills following neuroHIV. This paper presents a meta-analysis of randomised and non-randomised controlled trials (RCTs) to remediate attention skills following HIV CRT.
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- Authors: Kenyon, Chris R , Wolfs, Kenny , Osbak, Kara , van Hal, Guido , Zondo, Sizwe , van Lankveld, J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/450574 , vital:74962 , xlink:href="10.12688/f1000research.14951.2"
- Description: Despite medical advances in Highly Active Antiretroviral Therapy (HAART), patients living with HIV continue to be at risk for developing HIV-associated neurocognitive disorders (HAND). The optimization of non-HAART interventions, including cognitive rehabilitation therapy (CRT), shows promise in reversing the impact of HAND. No data exist indicating the efficacy of CRT in remediating attention skills following neuroHIV. This paper presents a meta-analysis of randomised and non-randomised controlled trials (RCTs) to remediate attention skills following HIV CRT.
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Cropland abandonment in South African smallholder communal lands: Land cover change (1950–2010) and farmer perceptions of contributing factors
- Blair, Dale, Shackleton, Charlie M, Mograbi, Penelope J
- Authors: Blair, Dale , Shackleton, Charlie M , Mograbi, Penelope J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/180297 , vital:43351 , xlink:href="https://doi.org/10.3390/land7040121"
- Description: Despite agricultural land abandonment threatening the food security and the livelihoods of smallholder farmers, it is pervasive globally and in developing countries. Yet land abandonment is an understudied aspect of land use change in social–ecological systems. Here we provide more information on this phenomenon by exploring cropland abandonment during 1950–2010 in four former South African ‘homelands’—part of the ‘Apartheid’ era racially-based land allocation programs—characterized by rural, smallholder farmers. Cropland abandonment 1950–2010 was widespread in all surveyed sites (KwaZulu: 0.08% year−1, Transkei: 0.13% year−1, Lebowa: 0.23% year−1, Venda: 0.28% year−1), with rates peaking between 1970 and 1990, with concomitant increases (up to 0.16% year−1) of woody vegetation cover at the expense of grassland cover. Active and past farmers attributed cropland abandonment to a lack of draught power, rainfall variability and droughts, and a more modernized youth disinclined to living a marginal agrarian lifestyle. We discuss the potential social and ecological implications of abandoned croplands at the local and regional scales, as the deagrarianization trend is unlikely to abate considering the failure of current South African national agricultural incentives.
- Full Text:
- Authors: Blair, Dale , Shackleton, Charlie M , Mograbi, Penelope J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/180297 , vital:43351 , xlink:href="https://doi.org/10.3390/land7040121"
- Description: Despite agricultural land abandonment threatening the food security and the livelihoods of smallholder farmers, it is pervasive globally and in developing countries. Yet land abandonment is an understudied aspect of land use change in social–ecological systems. Here we provide more information on this phenomenon by exploring cropland abandonment during 1950–2010 in four former South African ‘homelands’—part of the ‘Apartheid’ era racially-based land allocation programs—characterized by rural, smallholder farmers. Cropland abandonment 1950–2010 was widespread in all surveyed sites (KwaZulu: 0.08% year−1, Transkei: 0.13% year−1, Lebowa: 0.23% year−1, Venda: 0.28% year−1), with rates peaking between 1970 and 1990, with concomitant increases (up to 0.16% year−1) of woody vegetation cover at the expense of grassland cover. Active and past farmers attributed cropland abandonment to a lack of draught power, rainfall variability and droughts, and a more modernized youth disinclined to living a marginal agrarian lifestyle. We discuss the potential social and ecological implications of abandoned croplands at the local and regional scales, as the deagrarianization trend is unlikely to abate considering the failure of current South African national agricultural incentives.
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Cultural De-colonization versus Liberal approaches to abortion in Africa: The politics of representation and voice
- Chiweshe, Malvern T, Macleod, Catriona I
- Authors: Chiweshe, Malvern T , Macleod, Catriona I
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/443661 , vital:74142 , xlink:href="DOI/Handle/URL https://www.ajol.info/index.php/ajrh/article/view/175092"
- Description: Political discussions on abortion in Africa take place in the context of most countries having restrictive abortion legislation and high levels of unsafe abortion. In this paper two major political positions regarding abortion in Africa: a de-colonisation approach based on a homogenized view of ―culture‖, and a liberal approach based on ―choice‖ and rights are outlined. Using the Questions and Answers sessions of a United Nations event on maternal health in Africa as an exemplar of these positions, the paper argues that neither approach is emancipatory in the African context. A de-colonisation approach that uses static and homogenized understanding of ''culture'' risks engaging in a politics of representation that potentially silences the ―Other‖ (in this case women who terminate their pregnancies) and glosses over complexities and multiple power relations that exist on the continent. A liberal approach, premised on choice and reproductive rights, risks foregrounding individual women‘s agency at the expense of contextual dynamics, including the conditions that create unsupportable pregnancies. The paper argues for a grounded reproductive justice perspective that draws on the insights of the reproductive justice movement, but grounds these notions within the African philosophy of Hunhu/Ubuntu.
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- Authors: Chiweshe, Malvern T , Macleod, Catriona I
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/443661 , vital:74142 , xlink:href="DOI/Handle/URL https://www.ajol.info/index.php/ajrh/article/view/175092"
- Description: Political discussions on abortion in Africa take place in the context of most countries having restrictive abortion legislation and high levels of unsafe abortion. In this paper two major political positions regarding abortion in Africa: a de-colonisation approach based on a homogenized view of ―culture‖, and a liberal approach based on ―choice‖ and rights are outlined. Using the Questions and Answers sessions of a United Nations event on maternal health in Africa as an exemplar of these positions, the paper argues that neither approach is emancipatory in the African context. A de-colonisation approach that uses static and homogenized understanding of ''culture'' risks engaging in a politics of representation that potentially silences the ―Other‖ (in this case women who terminate their pregnancies) and glosses over complexities and multiple power relations that exist on the continent. A liberal approach, premised on choice and reproductive rights, risks foregrounding individual women‘s agency at the expense of contextual dynamics, including the conditions that create unsupportable pregnancies. The paper argues for a grounded reproductive justice perspective that draws on the insights of the reproductive justice movement, but grounds these notions within the African philosophy of Hunhu/Ubuntu.
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Current trend in synthesis, Post-Synthetic modifications and biological applications of Nanometal-Organic frameworks (NMOFs)
- Baa, Ebenezer, Watkins, Gary M, Krause, Rui W M, Tantoh, Derek N
- Authors: Baa, Ebenezer , Watkins, Gary M , Krause, Rui W M , Tantoh, Derek N
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/127042 , vital:35946 , https://doi.org/10.1002/cjoc.201800407
- Description: Since the early reports of MOFs and their interesting properties, research involving these materials has grown wide in scope and applications. Various synthetic approaches have ensued in view of obtaining materials with optimised properties, the extensive scope of application spanning from energy, gas sorption, catalysis biological applications has meant exponentially evolved over the years. The far‐reaching synthetic and PSM approaches and porosity control possibilities have continued to serve as a motivation for research on these materials. With respect to the biological applications, MOFs have shown promise as good candidates in applications involving drug delivery, BioMOFs, sensing, imaging amongst others. Despite being a while away from successful entry into the market, observed results in sensing, drug delivery, and imaging put these materials on the spot light as candidates poised to usher in a revolution in biology. In this regard, this review article focuses current approaches in synthesis, post functionalization and biological applications of these materials with particular attention on drug delivery, imaging, sensing and BioMOFs.
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- Authors: Baa, Ebenezer , Watkins, Gary M , Krause, Rui W M , Tantoh, Derek N
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/127042 , vital:35946 , https://doi.org/10.1002/cjoc.201800407
- Description: Since the early reports of MOFs and their interesting properties, research involving these materials has grown wide in scope and applications. Various synthetic approaches have ensued in view of obtaining materials with optimised properties, the extensive scope of application spanning from energy, gas sorption, catalysis biological applications has meant exponentially evolved over the years. The far‐reaching synthetic and PSM approaches and porosity control possibilities have continued to serve as a motivation for research on these materials. With respect to the biological applications, MOFs have shown promise as good candidates in applications involving drug delivery, BioMOFs, sensing, imaging amongst others. Despite being a while away from successful entry into the market, observed results in sensing, drug delivery, and imaging put these materials on the spot light as candidates poised to usher in a revolution in biology. In this regard, this review article focuses current approaches in synthesis, post functionalization and biological applications of these materials with particular attention on drug delivery, imaging, sensing and BioMOFs.
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