Bioinformatics and data analysis in microbiology:
- Authors: Tastan Bishop, Özlem
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/148104 , vital:38710 , ISBN 9781908230737 , https://books.google.co.za/books?id=-G07DwAAQBAJanddq=Bioinformatics+and+data+analysis+in+microbiologyandsource=gbs_navlinks_s
- Description: The rapid advancement of sequencing techniques, coupled with the new methodologies of bioinformatics to handle large-scale data analysis, are providing exciting opportunities for us to understand microbial communities from a variety of environments beyond previous imagination. This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a problem, talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The chapters include topics such as genome sequencing techniques, assembly, SNP analysis, annotation, comparative genomics, microbial community profiling, metagenomics, phylogenetic microarrays, barcoding and more. Each chapter is written by scientists who are expert in the field, and is peer-reviewed. Bioinformatics and Data Analysis in Microbiology is an essential book for researchers, lecturers and students involved in microbiology, bioinformatics and genome analysis.
- Full Text:
- Authors: Tastan Bishop, Özlem
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/148104 , vital:38710 , ISBN 9781908230737 , https://books.google.co.za/books?id=-G07DwAAQBAJanddq=Bioinformatics+and+data+analysis+in+microbiologyandsource=gbs_navlinks_s
- Description: The rapid advancement of sequencing techniques, coupled with the new methodologies of bioinformatics to handle large-scale data analysis, are providing exciting opportunities for us to understand microbial communities from a variety of environments beyond previous imagination. This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a problem, talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The chapters include topics such as genome sequencing techniques, assembly, SNP analysis, annotation, comparative genomics, microbial community profiling, metagenomics, phylogenetic microarrays, barcoding and more. Each chapter is written by scientists who are expert in the field, and is peer-reviewed. Bioinformatics and Data Analysis in Microbiology is an essential book for researchers, lecturers and students involved in microbiology, bioinformatics and genome analysis.
- Full Text:
General structural and functional features of molecular chaperones:
- Edkins, Adrienne L, Boshoff, Aileen
- Authors: Edkins, Adrienne L , Boshoff, Aileen
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/164808 , vital:41174 , ISBN 978-94-007-7437-7 , DOI: 10.1007/978-94-007-7438-4_2
- Description: Molecular chaperones are a group of structurally diverse and highly conserved ubiquitous proteins. They play crucial roles in facilitating the correct folding of proteins in vivo by preventing protein aggregation or facilitating the appropriate folding and assembly of proteins. Heat shock proteins form the major class of molecular chaperones that are responsible for protein folding events in the cell. This is achieved by ATP-dependent (folding machines) or ATP-independent mechanisms (holders). Heat shock proteins are induced by a variety of stresses, besides heat shock. The large and varied heat shock protein class is categorised into several subfamilies based on their sizes in kDa namely, small Hsps (HSPB), Hsp40 (DNAJ), Hsp60 (HSPD/E; Chaperonins), Hsp70 (HSPA), Hsp90 (HSPC), and Hsp100.
- Full Text:
- Authors: Edkins, Adrienne L , Boshoff, Aileen
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/164808 , vital:41174 , ISBN 978-94-007-7437-7 , DOI: 10.1007/978-94-007-7438-4_2
- Description: Molecular chaperones are a group of structurally diverse and highly conserved ubiquitous proteins. They play crucial roles in facilitating the correct folding of proteins in vivo by preventing protein aggregation or facilitating the appropriate folding and assembly of proteins. Heat shock proteins form the major class of molecular chaperones that are responsible for protein folding events in the cell. This is achieved by ATP-dependent (folding machines) or ATP-independent mechanisms (holders). Heat shock proteins are induced by a variety of stresses, besides heat shock. The large and varied heat shock protein class is categorised into several subfamilies based on their sizes in kDa namely, small Hsps (HSPB), Hsp40 (DNAJ), Hsp60 (HSPD/E; Chaperonins), Hsp70 (HSPA), Hsp90 (HSPC), and Hsp100.
- Full Text:
Imagining Civil Society in Zimbabwe and ‘Most of the World’:
- Authors: Helliker, Kirk D
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/144802 , vital:38380 , ISBN 9781461482628 , DOI: 10.1007/978-1-4614-8262-8_11
- Description: This chapter re-visits the notion of civil society in what Partha Chatterjee (The Politics of the Governed, 2004) calls ‘most of the world’ (beyond the capitalist metropoles) and, in doing so, uses Zimbabwe (and Africa more broadly) as an entry point into the literature on civil society. This chapter consists of four main sections. First, I discuss literature on civil society in Africa which, in the main, dichotomises civil society and the state empirically without any sustained theoretical reflections. Second, I provide an overview of Zimbabwean society and politics over the past decade and the ensuing debate, which in many ways produces a Manichean dualism whereby civil society is equated with progression and the state with regression. Third, I locate this conceptualisation of civil society within the broader international literature on civil society. These three sections, as a whole, highlight slippages in defining and understanding civil society: between civil society as a set of empirically identifiable organisational formations and civil society as a social space marked by civil liberties and voluntary arrangements in bourgeois society. Finally, I reimagine civil society in relation to ‘most of the world’.
- Full Text:
- Authors: Helliker, Kirk D
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/144802 , vital:38380 , ISBN 9781461482628 , DOI: 10.1007/978-1-4614-8262-8_11
- Description: This chapter re-visits the notion of civil society in what Partha Chatterjee (The Politics of the Governed, 2004) calls ‘most of the world’ (beyond the capitalist metropoles) and, in doing so, uses Zimbabwe (and Africa more broadly) as an entry point into the literature on civil society. This chapter consists of four main sections. First, I discuss literature on civil society in Africa which, in the main, dichotomises civil society and the state empirically without any sustained theoretical reflections. Second, I provide an overview of Zimbabwean society and politics over the past decade and the ensuing debate, which in many ways produces a Manichean dualism whereby civil society is equated with progression and the state with regression. Third, I locate this conceptualisation of civil society within the broader international literature on civil society. These three sections, as a whole, highlight slippages in defining and understanding civil society: between civil society as a set of empirically identifiable organisational formations and civil society as a social space marked by civil liberties and voluntary arrangements in bourgeois society. Finally, I reimagine civil society in relation to ‘most of the world’.
- Full Text:
Integrating customary practices and institutions into comanagement of small-scale fisheries:
- Kittinger, J N, Cinner, J E, Aswani, Shankar, White, A T
- Authors: Kittinger, J N , Cinner, J E , Aswani, Shankar , White, A T
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/178975 , vital:40099 , ISBN 9780520959606
- Description: This pioneering volume provides a blueprint for managing the challenges of ocean conservation using marine historical ecology—an interdisciplinary area of study that is helping society to gain a more in-depth understanding of past human-environmental interactions in coastal and marine ecosystems and of the ecological and social outcomes associated with these interactions. Developed by groundbreaking practitioners in the field, Marine Historical Ecology in Conservation highlights the innovative ways that historical ecology can be applied to improve conservation and management efforts in the oceans. The book focuses on four key challenges that confront marine conservation: (1) recovering endangered species, (2) conserving fisheries, (3) restoring ecosystems, and (4) engaging the public. Chapters emphasize real-world conservation scenarios appropriate for students, faculty, researchers, and practitioners in marine science, conservation biology, natural resource management, paleoecology, and marine and coastal archaeology. By focusing on success stories and applied solutions, this volume delivers the required up-to-date science and tools needed for restoration and protection of ocean and coastal ecosystems.
- Full Text:
- Authors: Kittinger, J N , Cinner, J E , Aswani, Shankar , White, A T
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/178975 , vital:40099 , ISBN 9780520959606
- Description: This pioneering volume provides a blueprint for managing the challenges of ocean conservation using marine historical ecology—an interdisciplinary area of study that is helping society to gain a more in-depth understanding of past human-environmental interactions in coastal and marine ecosystems and of the ecological and social outcomes associated with these interactions. Developed by groundbreaking practitioners in the field, Marine Historical Ecology in Conservation highlights the innovative ways that historical ecology can be applied to improve conservation and management efforts in the oceans. The book focuses on four key challenges that confront marine conservation: (1) recovering endangered species, (2) conserving fisheries, (3) restoring ecosystems, and (4) engaging the public. Chapters emphasize real-world conservation scenarios appropriate for students, faculty, researchers, and practitioners in marine science, conservation biology, natural resource management, paleoecology, and marine and coastal archaeology. By focusing on success stories and applied solutions, this volume delivers the required up-to-date science and tools needed for restoration and protection of ocean and coastal ecosystems.
- Full Text:
Participatory Action Research into ways in which Dance Movement Psychotherapy can promote personal and social change in a South African:
- Authors: Copteros, Athina
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142027 , vital:38025 , ISBN Healing and Social Transformation in Mental Healthcare in South Africa Conference, University of Cape Town, 14-15 July
- Description: Participatory Action Research into ways in which Dance Movement Psychotherapy can promote personal and social change in a South African.
- Full Text:
- Authors: Copteros, Athina
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/142027 , vital:38025 , ISBN Healing and Social Transformation in Mental Healthcare in South Africa Conference, University of Cape Town, 14-15 July
- Description: Participatory Action Research into ways in which Dance Movement Psychotherapy can promote personal and social change in a South African.
- Full Text:
Running with the jackals: Antjie Krog the journalist
- Authors: Garman, Anthea
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/159813 , vital:40346 , ISBN 9781869142537
- Description: Antjie Krog: An Ethics of Body and Otherness brings together critical responses to the fascinating life's work of one of South Africa's most prominent writers and public figures. As the writer of the Truth and Reconciliation Commission chronicle, Country of My Skull (1998), other works of creative non-fiction, Afrikaans poetry, translations, and journalism, Antjie Krog has, over a career spanning four decades, produced an important body of work informed by her no-holds-barred openness, acute self-awareness, and social engagement. As a public figure, she is both a dissident who provocatively challenges norms and a mediator between cultures. In this book, scholars from a range of disciplines explore the many facets of Antjie Krog's work. The book's essays focus on identity, race, gender, apartheid, trauma, and transformation. There is also a thought-provoking interview with Krog on translation. This book will be of interest to scholars of postcolonial literature, politics, South African literature, as well as media and translation studies.
- Full Text:
- Authors: Garman, Anthea
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/159813 , vital:40346 , ISBN 9781869142537
- Description: Antjie Krog: An Ethics of Body and Otherness brings together critical responses to the fascinating life's work of one of South Africa's most prominent writers and public figures. As the writer of the Truth and Reconciliation Commission chronicle, Country of My Skull (1998), other works of creative non-fiction, Afrikaans poetry, translations, and journalism, Antjie Krog has, over a career spanning four decades, produced an important body of work informed by her no-holds-barred openness, acute self-awareness, and social engagement. As a public figure, she is both a dissident who provocatively challenges norms and a mediator between cultures. In this book, scholars from a range of disciplines explore the many facets of Antjie Krog's work. The book's essays focus on identity, race, gender, apartheid, trauma, and transformation. There is also a thought-provoking interview with Krog on translation. This book will be of interest to scholars of postcolonial literature, politics, South African literature, as well as media and translation studies.
- Full Text:
Study South Africa
- International Education Association of South Africa (IEASA), Jooste, Nico
- Authors: International Education Association of South Africa (IEASA) , Jooste, Nico
- Date: 2014
- Subjects: Education, Higher -- South Africa , Education and globalization -- South Africa Student mobility -- Africa International education -- South Africa Education, Higher -- International cooperation , Universities and colleges -- South Africa , Technical Institutes -- South Africa , Vocational guidance -- South Africa
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/64864 , vital:28621 , ISBN 9780620620123
- Description: [Editor's Letter]: This 14th edition of Study South Africa foregrounds the celebration of 20 years of a democratic South Africa. Patrick Fish was commissioned to write a series of articles reflecting the development of South African Higher Education since 1994 for this edition. Reading through this the reader will hopefully experience a sense of the transformation of the South African Higher Education system. Although we all agree in South Africa that we are not done yet, we also recognise that given the South African realities, the change from a race based and fragmented system of higher education to a single but diverse system is well under way. The South African Universities transformed from mostly mono cultural to multicultural institutions that largely reflects the composition of the South African population. The University campuses also demonstrate the institutional appetite to be international. Not only do they jointly house more than 50,000 international students but are also involved in numerous ways in bringing the benefits of being globally connected to the local communities. We are one of the few higher education systems that largely fund our international activities from institutional budgets. This is one of the main reasons that South African Universities practice a style of internationalisation that is relevant to our institutional needs, as well as the local and national needs. Through our internationalisation endeavours we have connected with the rest of Africa in a very special way. Not only do we educate large numbers of students from other African countries but through the South African Higher Education alumni that now live all over the African continent we have built permanent connections that will enhance and develop long standing relationships. IEASA celebrates with all South Africans 20 years of democracy and realise that it is indeed a privilege to be practitioners in transformed ‘knowledge cities’. We are, however, saddened by the incidents of intolerance and destruction in other parts of the world that make the work of higher education institutions impossible, and can only in solidarity with those scholars at risk celebrate with deep appreciation the efforts and determination of those South Africans that made it possible for us to be Universities in a free and democratic society. , 14th Edition
- Full Text:
- Authors: International Education Association of South Africa (IEASA) , Jooste, Nico
- Date: 2014
- Subjects: Education, Higher -- South Africa , Education and globalization -- South Africa Student mobility -- Africa International education -- South Africa Education, Higher -- International cooperation , Universities and colleges -- South Africa , Technical Institutes -- South Africa , Vocational guidance -- South Africa
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/64864 , vital:28621 , ISBN 9780620620123
- Description: [Editor's Letter]: This 14th edition of Study South Africa foregrounds the celebration of 20 years of a democratic South Africa. Patrick Fish was commissioned to write a series of articles reflecting the development of South African Higher Education since 1994 for this edition. Reading through this the reader will hopefully experience a sense of the transformation of the South African Higher Education system. Although we all agree in South Africa that we are not done yet, we also recognise that given the South African realities, the change from a race based and fragmented system of higher education to a single but diverse system is well under way. The South African Universities transformed from mostly mono cultural to multicultural institutions that largely reflects the composition of the South African population. The University campuses also demonstrate the institutional appetite to be international. Not only do they jointly house more than 50,000 international students but are also involved in numerous ways in bringing the benefits of being globally connected to the local communities. We are one of the few higher education systems that largely fund our international activities from institutional budgets. This is one of the main reasons that South African Universities practice a style of internationalisation that is relevant to our institutional needs, as well as the local and national needs. Through our internationalisation endeavours we have connected with the rest of Africa in a very special way. Not only do we educate large numbers of students from other African countries but through the South African Higher Education alumni that now live all over the African continent we have built permanent connections that will enhance and develop long standing relationships. IEASA celebrates with all South Africans 20 years of democracy and realise that it is indeed a privilege to be practitioners in transformed ‘knowledge cities’. We are, however, saddened by the incidents of intolerance and destruction in other parts of the world that make the work of higher education institutions impossible, and can only in solidarity with those scholars at risk celebrate with deep appreciation the efforts and determination of those South Africans that made it possible for us to be Universities in a free and democratic society. , 14th Edition
- Full Text:
The networking of chaperones by co-chaperones: control of cellular protein homeostasis
- Edkins, Adrienne L, Blatch, Gregory L
- Authors: Edkins, Adrienne L , Blatch, Gregory L
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/165107 , vital:41209 , ISBN 978-3-319-11731-7
- Description: Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
- Full Text:
- Authors: Edkins, Adrienne L , Blatch, Gregory L
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/165107 , vital:41209 , ISBN 978-3-319-11731-7
- Description: Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
- Full Text:
Troubling White Englishness in South Africa: a self-interrogation of privilege, complicity citizenship, and belonging
- Authors: Garman, Anthea
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/159746 , vital:40339 , ISBN 978-0739192962
- Description: Unveiling Whiteness in the Twenty-First Century: Global Manifestations, Transdisciplinary Interventions is a tightly interconnected and richly collaborative book that will advance our understanding of why it is so difficult to re-form and reimagine whiteness in the twenty-first century. Composed after the election of the first black U.S. president, post-global financial crisis, more than a decade after 9/11, and concomitant with a rash of xenophobic incidents across the globe, the book distills several key themes associated with a post-millennial global whiteness: the individual and collective emotions of whiteness, the recentering of whiteness through governing and legal strategies, and the retreats from social equity and justice that have characterized the late twentieth and twenty-first century nation state. It also attempts the difficult work of reimagining white identities and cultures for a new era.
- Full Text:
- Authors: Garman, Anthea
- Date: 2014
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/159746 , vital:40339 , ISBN 978-0739192962
- Description: Unveiling Whiteness in the Twenty-First Century: Global Manifestations, Transdisciplinary Interventions is a tightly interconnected and richly collaborative book that will advance our understanding of why it is so difficult to re-form and reimagine whiteness in the twenty-first century. Composed after the election of the first black U.S. president, post-global financial crisis, more than a decade after 9/11, and concomitant with a rash of xenophobic incidents across the globe, the book distills several key themes associated with a post-millennial global whiteness: the individual and collective emotions of whiteness, the recentering of whiteness through governing and legal strategies, and the retreats from social equity and justice that have characterized the late twentieth and twenty-first century nation state. It also attempts the difficult work of reimagining white identities and cultures for a new era.
- Full Text:
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