Assessment of topical corticosteroid preparations: the human skin-blanching assay
- Authors: Haigh, John M , Kanfer, Isadore
- Date: 1984
- Language: English
- Type: text , Article
- Identifier: vital:6374 , http://hdl.handle.net/10962/d1006284
- Description: (From the introduction) Since the introduction of topical corticosteroid formulations, their use has become widespread, being prescribed for a large variety of dermatological conditions. This widespread use has created a need for a reliable method of assessing the various dosage forms of these compounds. Clinical trials are laborious, costly and difficult to mount as well as being impractical for the screening of large numbers of drugs. Patients suffering from dermatological complaints are not ideal subjects for the testing of topical corticosteroid preparations as it is difficult to obtain standardized lesions which are necessary for the comparison of results between patients (Baker and Sattar, 1968). For these reasons a number of methods have been developed for the screening of novel corticosteroids and testing of topical corticosteroid formulations.
- Full Text:
Geochemistry and petrogenesis of the Etendeka volcanic rocks from SWA Namibia
- Authors: Erlank, Anthony J , Marsh, Julian S , Duncan, Andrew R , Miller, R M , Hawkesworth, C J , Betton, P J , Rex, D C
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/133923 , vital:37041 , https://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetailamp;idt=6519919
- Description: The volcanic rocks of the Etendeka Formation from north-west SWA/Namibia have a present-day coverage of 70,000 km² and comprise a series of interbedded basalts, latites and quartz latites, together with four varieties of intrusive dolerite. Apart from one group of dolerites (regional dolerites) which have mineralogical and geochemical similarities to the Lesotho Formation lavas from the Central area, the Etendeka volcanics differ from all other Karoo volcanics by virtue of their Cretaceous age, stratigraphy, mineralogy, geochemistry, and range in mineralogical, elemental and isotopic compositions for the basaltic rocks.
- Full Text:
Geochemistry of Karoo basalts and dolerites in the northeastern Orange Free State: Recognition and origin of the new Karoo basalt magma types.
- Authors: Marsh, J S
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71283 , vital:29829
- Description: One of the most significant results emerging from the Karoo Volcanics Project of the NGP ls the recognition of a number of geochemically distinct basalt magma types occurring within the lower part of the Karoo volcanic pile in the Northeastern Cape and Southern Lesotho.
- Full Text: false
Geochemistry of Karoo basalts and dolerites in the northeastern Orange Free State: Recognition and origin of the new Karoo basalt magma types.
- Authors: Marsh, Julian S
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/71288 , vital:29830
- Description: One of the most significant results emerging from the Karoo Volcanics Project of the NGP ls the recognition of a number of geochemically distinct basalt magma types occurring within the lower part of the Karoo volcanic pile in the Northeastern Cape and Southern Lesotho.
- Full Text:
Karoo basalts of the Springbok Flats: geochemistry and correlation
- Authors: Marsh, Julian S
- Date: 1984
- Language: English
- Type: text , abstracts
- Identifier: http://hdl.handle.net/10962/131634 , vital:36706
- Description: Karoo basalts underlie an area of about 3750 km2 of the Springbok Flats. Four boreholes were logged and sampled for detailed petrographic and chemical analysis. The Springbok Flats basalt's chemical composition is compared with those of the Sabie River Formation of the Lebombo and the Lesotho type of the Central Karoo area. Sr- and Nd- isotopic data were also used in determining the chemical composition. The study also allows the geographical extent of the incompatible element-enriched clan of Karoo Lavas to be refined.
- Full Text:
Regional geochemistry of the Karoo igneous province
- Authors: Duncan, Andrew R , Erlank, Anthony J , Marsh, Julian S
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/134154 , vital:37079 , https://inis.iaea.org/search/searchsinglerecord.aspx?recordsFor=SingleRecordamp;RN=15001076
- Description: The extrusive and intrusive rocks of the Karoo Igneous Province are dominantly of basaltic or rhyolitic (sensu lato) composition. There are, however, a considerable variety of other rock types within the province including picritic basalts, nephelinites, shoshonites, latites, andesites and dacites. This paper deals with the geochemistry of the Karoo igneous province.
- Full Text:
Rhodes University Graduation Ceremony 1984
- Authors: Rhodes University
- Date: 1984
- Language: English
- Type: text
- Identifier: vital:8115 , http://hdl.handle.net/10962/d1004573
- Description: Rhodes University Graduation Ceremonies on Friday, 13 April 1984 at 8 p.m. [and] on Saturday, 14 April 1984 at 10 a.m. in the 1820 Settlers National Monument.
- Full Text:
Strontium isotope characterization of Karoo volcanic rocks
- Authors: Bristow, J W , Allsopp, H L , Erlank, Anthony J , Marsh, Julian S , Armstrong, R A
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/134176 , vital:37081 , https://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetailamp;idt=6453595
- Description: Karoo volcanics of both mafic and felsic composition cover large areas of southern Africa, and are characterized by considerable ranges in their initial 87Sr/86Sr (i.e. Ro) ratios. Mafic volcanics from the eastern and western continental margins show the greatest range in Ro ratios, i.e. Lebombo-Nuanetsi area: 0.7035-0.7134 and Etendeka: 0.7030-0.7135 respectively. In the Central Karoo area the mafic rocks show a smaller spread of ratios: 0.7046-0.7094.
- Full Text:
The chemistry and petrogenesis of igneous rocks of the Karoo central area, southern Africa
- Authors: Eales, Hugh V , Marsh, Julian S
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/133934 , vital:37042 , https://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetailamp;idt=6519911
- Description: Outcrops of the Jurassic Karoo basalts and dolerites in central South Africa are remnants of an intracratonic continental igneous suite whose volume probably once exceeded 1.5 x 106 km³. Basic rocks with 6-8% MgO, 50-55% Si02 and Mg-number = 53-67 are overwhelmingly dominant in the Central area suite. Application of discriminant analysis to a data set of major and trace element analyses of the basic rocks confirms field and petrographic evidence that a number of compositionally distinct basalt magma types exist in the Central area.
- Full Text:
The Karoo igneous province: an introduction
- Authors: Eales, Hugh V , Marsh, Julian S , Cox, K G
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/133945 , vital:37043 , http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetailamp;idt=6519910
- Description: The Karoo rocks are amongst the earliest manifestations of igneous activity accompanying the break-up of Gondwanaland during the early Mesozoic. Remnants of the once extensive lava sequence and the associated dolerite sills are found throughout southern Africa south of latitude 150S, the present outcrop being ca. 140,000 km². The main peak of volcanic activity is dated at about 190 m.y. and is probably coincident with the earliest stages of the opening of the Indian Ocean by the separation of Antarctica from southern Africa.
- Full Text:
The role of continental lithosphere in the generation of the Karoo volcanic rocks: evidence from combined Nd-and Sr-isotope studies
- Authors: Hawkesworth, C J , Marsh, Julian S , Duncan, Andrew R , Erlank, Anthony J , Norry, M J
- Date: 1984
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/134165 , vital:37080 , https://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetailamp;idt=6453596
- Description: 143Nd/144Nd, 87Sr/86Sr, Sm and Nd analyses are reported on suites of Karoo volcanic rocks from the four sub-areas of Nuanetsi-north Lebombo, south Lebombo, the Central area, and north-west SWA/Namibia. Only seven (12%) of the samples analysed have positive ENd values similar to those found in the majority of recent mantle-derived rocks. Most of the rest have negative ENd (-1.0 to -17.1) and positive ESr, (+3.0 to +240) and thus must contain at least a contribution from source areas which were both old, and had lower Sm/Nd and higher Rh/Sr ratios than the bulk earth.
- Full Text:
The winter diet of gentoo penguins at Marion Island
- Authors: LaCock, G D , Hecht, Thomas , Klages, N
- Date: 1984
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/448453 , vital:74731 , https://doi.org/10.1080/00306525.1984.9634486
- Description: The diet of Gentoo Penguins Pygoscelis papua at Marion Island was studied during September 1982. Samples were obtained from 64 birds using a stomach-pump. Fish accounted for 70% of the diet by wet weight, and crustaceans 30%. Fishes occurred in 72% of the samples, crustaceans in 75%, cephalopods in 13%, and molluscs in 8%. Cephalopods and molluscs did not form a significant proportion of any single sample. Harpagifer georgianus was the predominant fish in the diet (92,7% of otoliths recovered), and Nauticaris marionis was the only crustacean.
- Full Text: