Health and politics : appraisal and evaluation of the provision of health and mental health services for Blacks in South Africa
- Authors: O'Donoghue, Sean B
- Date: 1989
- Subjects: Black people -- Mental health -- South Africa , Mental health services -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2909 , http://hdl.handle.net/10962/d1002074
- Description: The aim of this study has been to examine, in the light of recent events in the field of Health Care in South Africa, the remarks and claims made by the World Health Organization, and the American Psychiatric Association between 1976 and 1978 on Health Care services, as provided for Blacks, by the South African government. In two reports, these organizations instituted the earliest, and arguably most significant claims against South Africa's system of Health Care. This study sketches firstly the political genesis and social context of the WHO, and APA examinations. Secondly, this study evaluates responses made by the South African State to the critical climate inspired by the above mentioned reports, through a close analysis of recent events associated with the politics, and provision of Health Care Facilities - particularly with regard to Black South Africans. This analysis suggests that the governments' earlier tentative policy of privatisation (which was soundly condemned by WHO and the APA) has been even more enthusiastically pursued - in contradiction to it's avowed policies of Commu ity Health Care, and to the continuing detriment of those South African communities who are in most need of adequate Health Care services. The study concludes that the criticisms raised by the WHO and APA had the effect of inspiring positive reforms in South Africa's health services, but in no way thwarted the governments', at first only tentative plans, to increasingly privatise it's psychiatric and other medical institutions.
- Full Text:
- Authors: O'Donoghue, Sean B
- Date: 1989
- Subjects: Black people -- Mental health -- South Africa , Mental health services -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: vital:2909 , http://hdl.handle.net/10962/d1002074
- Description: The aim of this study has been to examine, in the light of recent events in the field of Health Care in South Africa, the remarks and claims made by the World Health Organization, and the American Psychiatric Association between 1976 and 1978 on Health Care services, as provided for Blacks, by the South African government. In two reports, these organizations instituted the earliest, and arguably most significant claims against South Africa's system of Health Care. This study sketches firstly the political genesis and social context of the WHO, and APA examinations. Secondly, this study evaluates responses made by the South African State to the critical climate inspired by the above mentioned reports, through a close analysis of recent events associated with the politics, and provision of Health Care Facilities - particularly with regard to Black South Africans. This analysis suggests that the governments' earlier tentative policy of privatisation (which was soundly condemned by WHO and the APA) has been even more enthusiastically pursued - in contradiction to it's avowed policies of Commu ity Health Care, and to the continuing detriment of those South African communities who are in most need of adequate Health Care services. The study concludes that the criticisms raised by the WHO and APA had the effect of inspiring positive reforms in South Africa's health services, but in no way thwarted the governments', at first only tentative plans, to increasingly privatise it's psychiatric and other medical institutions.
- Full Text:
High-performance liquid chromatographic studies of the acid degradation, pharmacokinetics and comparative bioavailability of erythromycin
- Authors: Glew, Fiona
- Date: 1989
- Subjects: High performance liquid chromatography , Erythromycin -- Analysis , Erythromycin -- Pharmacokinetics , Erythromycin -- Bioavailability
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3737 , http://hdl.handle.net/10962/d1001529
- Description: Erythromycin is a macrolide antibiotic with a spectrum similar to penicillin and is used mainly in the treatment of infections caused by gram-positive organisms. Since its discovery in 1952, erythromycin has achieved wide-spread clinical use. Susceptibility of erythromycin base to inactivation by acid results in decreased availability following exposure to acidic gastric fluids. Formulation of acid resistant dosage forms and the preparation of acid stable chemical derivatives have been attempted to improve absorption and subsequent clinical efficacy . Two of the most commonly used erythromycin derivatives are the stearic acid salt (erythromycin stearate) and the lauryl sulphate salt of the propionyl ester (erythromycin estolate). Although it has been known for many years that erythromycin is susceptible to acid degradation, very few reports on the stability of erythromycin in aqueous solutions appear in the literature. In this study, a high-performance liquid chromatographic system using electrochemical detection was employed for a kinetic study of erythromycin degradation. The effect of varying acid pH on the degradation rate of both erythromycin base and erythromycin stearate, and the effect on the hydrolysis rate of erythromycin estolate is presented. In addition, the effect of temperature on erythromycin degradation was also investigated. Until recently, the majority of pharmacokinetic and bioavailability studies have utilized relatively non-specific microbiological assay procedures. However, in this study a solid phase extraction, followed by the use of a high-performance liquid chromatographic system using electrochemical coulometric detection was employed for the determination of erythromycin in biological fluids. Human volunteers each received enteric coated erythromycin base pellets in capsule dosage form and also film coated erythromycin stearate tablets on separate occasions. Results from the clinical trials revealed the enteric coated erythromycin base pellets had a greater bioavailability than the film coated erythromycin stearate tablets. Computer fitting of data revealed no intra-volunteer variability in elimination rate constants, suggesting differences in serum levels following administration of both dosage forms are due to variation in absorption. Results from the clinical trials were also compared with those obtained from a further trial, during which the same volunteers received erythromycin estolate
- Full Text:
- Authors: Glew, Fiona
- Date: 1989
- Subjects: High performance liquid chromatography , Erythromycin -- Analysis , Erythromycin -- Pharmacokinetics , Erythromycin -- Bioavailability
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3737 , http://hdl.handle.net/10962/d1001529
- Description: Erythromycin is a macrolide antibiotic with a spectrum similar to penicillin and is used mainly in the treatment of infections caused by gram-positive organisms. Since its discovery in 1952, erythromycin has achieved wide-spread clinical use. Susceptibility of erythromycin base to inactivation by acid results in decreased availability following exposure to acidic gastric fluids. Formulation of acid resistant dosage forms and the preparation of acid stable chemical derivatives have been attempted to improve absorption and subsequent clinical efficacy . Two of the most commonly used erythromycin derivatives are the stearic acid salt (erythromycin stearate) and the lauryl sulphate salt of the propionyl ester (erythromycin estolate). Although it has been known for many years that erythromycin is susceptible to acid degradation, very few reports on the stability of erythromycin in aqueous solutions appear in the literature. In this study, a high-performance liquid chromatographic system using electrochemical detection was employed for a kinetic study of erythromycin degradation. The effect of varying acid pH on the degradation rate of both erythromycin base and erythromycin stearate, and the effect on the hydrolysis rate of erythromycin estolate is presented. In addition, the effect of temperature on erythromycin degradation was also investigated. Until recently, the majority of pharmacokinetic and bioavailability studies have utilized relatively non-specific microbiological assay procedures. However, in this study a solid phase extraction, followed by the use of a high-performance liquid chromatographic system using electrochemical coulometric detection was employed for the determination of erythromycin in biological fluids. Human volunteers each received enteric coated erythromycin base pellets in capsule dosage form and also film coated erythromycin stearate tablets on separate occasions. Results from the clinical trials revealed the enteric coated erythromycin base pellets had a greater bioavailability than the film coated erythromycin stearate tablets. Computer fitting of data revealed no intra-volunteer variability in elimination rate constants, suggesting differences in serum levels following administration of both dosage forms are due to variation in absorption. Results from the clinical trials were also compared with those obtained from a further trial, during which the same volunteers received erythromycin estolate
- Full Text:
Identification and analysis of manual materials handling tasks within a commercial warehouse in South Africa
- Authors: Walraven, Lynne Louise
- Date: 1989
- Subjects: Materials handling -- Safety measures , Industrial safety -- South Africa , Lifting and carrying -- Safety measures
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:5159 , http://hdl.handle.net/10962/d1015722
- Description: Lifting and overstraining are major causative factors related to musculoskeletal injuries and low back pain. A great number of work-related injuries arise from the handling and/or mishandling of materials. Hence there is a need to quantify risk factors in situ and develop guidelines for safe lifting practises in industry. The aim of this study was to make appropriate in situ quantification, within a commercial warehouse, of the stresses and physical demands imposed on the worker when performing two handed lifts in the sagittal plane. The performance of employees was assessed under normal working conditions through an observational methodology of data collection. Task performance evaluation was based on detailed measurement of all containers handled, an activity and time analysis, and the 'Work Practices Guide to Manual Lifting’ (NIOSH, 1981) which was used as the primary guide to developing theoretical recommendations to probable MMH risk factors for the workers involved. Of the 191 tasks analysed 103 were deemed unsuitable. Appropriate task factor adjustments were made where necessary to both the frequency and Hfactors (horizontal distance between the centre of gravity of the container and that of the worker) in order to reduce the risk factor for the workers
- Full Text:
- Authors: Walraven, Lynne Louise
- Date: 1989
- Subjects: Materials handling -- Safety measures , Industrial safety -- South Africa , Lifting and carrying -- Safety measures
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:5159 , http://hdl.handle.net/10962/d1015722
- Description: Lifting and overstraining are major causative factors related to musculoskeletal injuries and low back pain. A great number of work-related injuries arise from the handling and/or mishandling of materials. Hence there is a need to quantify risk factors in situ and develop guidelines for safe lifting practises in industry. The aim of this study was to make appropriate in situ quantification, within a commercial warehouse, of the stresses and physical demands imposed on the worker when performing two handed lifts in the sagittal plane. The performance of employees was assessed under normal working conditions through an observational methodology of data collection. Task performance evaluation was based on detailed measurement of all containers handled, an activity and time analysis, and the 'Work Practices Guide to Manual Lifting’ (NIOSH, 1981) which was used as the primary guide to developing theoretical recommendations to probable MMH risk factors for the workers involved. Of the 191 tasks analysed 103 were deemed unsuitable. Appropriate task factor adjustments were made where necessary to both the frequency and Hfactors (horizontal distance between the centre of gravity of the container and that of the worker) in order to reduce the risk factor for the workers
- Full Text:
In vitro diffusion cell design and validation. I. A stability-indicating high-performance liquid chromatographic assay for betamethasone 17-valerate in purified isopropyl myristate receptor phase
- Smith, Eric W, Haigh, John M
- Authors: Smith, Eric W , Haigh, John M
- Date: 1989
- Language: English
- Type: text , Article
- Identifier: vital:6431 , http://hdl.handle.net/10962/d1006595
- Description: Introduction: The development of a reliable in vitro permeation system necessitates the use of a precise and accurate method of quantifying the amount of permeant partitioning from the membrane into the cell receptor phase. Aqueous donor and receptor chamber fluids have been used in the majority of reported investigations, which makes quantitative permeant analysis relatively facile. Alternatively, radiolabelled diffusants have been used and flux rates monitored by scintillation counting, obviating the need for chromatographic separation of the receptor-phase components. However, this technique is not applicable when nonlabelled compounds or commercial dosage forms are to be evaluated by a cell system. Furthermore, several studies indicate that aqueous receptor phases may not present an optimal partitioning environment for certain lipophilic permeants (1-4), thereby impairing accurate flux monitoring due to limited diffusant solubility. Several attempts have therefore been made to improve the partitioning environment within these systems, by the addition of surfactants for example (4). A lipophilic receptor environment appears beneficial for corticosteroid partitioning, and thus, the use of isopropyl myristate has been investigated because of its bipolar properties that tend to mimic the biochemical composition of the skin (5,6). Betamethasone 17-valerate and its 21-valerate degradation product are highly soluble in isopropyl myristate and this nonaqueous solvent will not augment C-17-to-C-21 ester degradation reactions.
- Full Text:
- Authors: Smith, Eric W , Haigh, John M
- Date: 1989
- Language: English
- Type: text , Article
- Identifier: vital:6431 , http://hdl.handle.net/10962/d1006595
- Description: Introduction: The development of a reliable in vitro permeation system necessitates the use of a precise and accurate method of quantifying the amount of permeant partitioning from the membrane into the cell receptor phase. Aqueous donor and receptor chamber fluids have been used in the majority of reported investigations, which makes quantitative permeant analysis relatively facile. Alternatively, radiolabelled diffusants have been used and flux rates monitored by scintillation counting, obviating the need for chromatographic separation of the receptor-phase components. However, this technique is not applicable when nonlabelled compounds or commercial dosage forms are to be evaluated by a cell system. Furthermore, several studies indicate that aqueous receptor phases may not present an optimal partitioning environment for certain lipophilic permeants (1-4), thereby impairing accurate flux monitoring due to limited diffusant solubility. Several attempts have therefore been made to improve the partitioning environment within these systems, by the addition of surfactants for example (4). A lipophilic receptor environment appears beneficial for corticosteroid partitioning, and thus, the use of isopropyl myristate has been investigated because of its bipolar properties that tend to mimic the biochemical composition of the skin (5,6). Betamethasone 17-valerate and its 21-valerate degradation product are highly soluble in isopropyl myristate and this nonaqueous solvent will not augment C-17-to-C-21 ester degradation reactions.
- Full Text:
In vitro systems for the assessment of drug release from topical formulations and trans-membrane permeation
- Smith, Eric W, Haigh, John M
- Authors: Smith, Eric W , Haigh, John M
- Date: 1989
- Language: English
- Type: Book chapter
- Identifier: vital:6441 , http://hdl.handle.net/10962/d1006628
- Description: Numerous experimental methods have been developed to investigate drug release from vehicles and the percutaneous absorption of topically applied chemicals. The objective of this research is often to find correlation between laboratory results and the transdermal absorption experienced by living subjects so that in vivo experimentation may be curtailed. In many instances, the diverse experimental techniques tend to obscure absorption-controlling factors and complicate inter study comparisons, rather than clarify the complex transdermal absorption process. Moreover, lack of agreement between results may occasionally be ascribed to shortcomings in the in vitro methodology employed. The benefits of using an in vitro cell system for the preliminary testing of drug permeation in the laboratory are obvious. The environmental and diffusion variables may be controlled in an attempt to elucidate specific factors affecting the kinetic processes and drug bioavailability. Investigations are complex because of the multiple, interrelated events underlying the processes of drug partitioning from the applied vehicle and diffusion through the portals of the stratum corneum to the myriad of metabolic, binding, and clearance activities in the lower epidermal and dermal strata.
- Full Text:
- Authors: Smith, Eric W , Haigh, John M
- Date: 1989
- Language: English
- Type: Book chapter
- Identifier: vital:6441 , http://hdl.handle.net/10962/d1006628
- Description: Numerous experimental methods have been developed to investigate drug release from vehicles and the percutaneous absorption of topically applied chemicals. The objective of this research is often to find correlation between laboratory results and the transdermal absorption experienced by living subjects so that in vivo experimentation may be curtailed. In many instances, the diverse experimental techniques tend to obscure absorption-controlling factors and complicate inter study comparisons, rather than clarify the complex transdermal absorption process. Moreover, lack of agreement between results may occasionally be ascribed to shortcomings in the in vitro methodology employed. The benefits of using an in vitro cell system for the preliminary testing of drug permeation in the laboratory are obvious. The environmental and diffusion variables may be controlled in an attempt to elucidate specific factors affecting the kinetic processes and drug bioavailability. Investigations are complex because of the multiple, interrelated events underlying the processes of drug partitioning from the applied vehicle and diffusion through the portals of the stratum corneum to the myriad of metabolic, binding, and clearance activities in the lower epidermal and dermal strata.
- Full Text:
Interactions between ants, herbivorous insects and bracken (Pteridium aquilinum), a fern with extrafloral nectaries
- Authors: Rashbrook, Vanessa Karin
- Date: 1989
- Subjects: Arthropod pests -- South Africa Ants -- South Africa Ferns -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5592 , http://hdl.handle.net/10962/d1002042
- Description: Bracken (Pteridium aquilinum) is a cosmopolitan species of fern which possesses extrafloral nectaries. A survey of the arthropod fauna associated with the plant throughout its range in South Africa identified the most widespread and damaging bracken herbivores and those species most likely to be influenced by ants visiting the extrafloral nectaries. Seventeen herbivorous arthropods were found to be definitely feeding on bracken and a further thirteen species with a less certain status were recorded. In addition, several species of ants were observed on the fronds and feeding at the extrafloral nectarie. On the basis of their widespread distribution and abundance, four bracken herbivores emerged as being particularly detrimental to the plant in South Africa. They were an eriophyid gall mite, a leafhopper and two moths. The biology of the two lepidopterans, Appana cinisigna and Panotima sp., suggested that they were potentially vulnerable to ants at various stages of their life histories. Laboratory experiments were undertaken to observe ant-lepidopteran interactions under controlled conditions. The ant Crematogaster peringueyi rapidly removed exposed A. cini igna eggs, but did not appear to regard Panotima eggs as food items. Small instar larvae of both species proved vulnerable, but the larger larvae appeared capable of escaping ant predation. Ant exclusion experiments in the field, using natural and artificially augmented ant densities, were carried out at two sites near Grahamstown. The dominant ant species was C. peringueyi. Neither the numbers of lepidopterans nor levels of herbivory were significantly reduced by the presence of ants . Despite the implications of the laboratory tests, the results of these field experiments did not support the hypothesis that ants which visit bracken extrafloral nectaries benefit the plant. Ant-bracken field studies on other continents also reported no significant ant-related effects, though marginal reductions in the abundance of certain herbivores have been noted at one site in the U.K. Since ant protection does not appear to be an inevitable consequence of having extrafloral nectaries, their value to bracken is in some doubt. The most likely situation where effective protection will occur is when high densities of vulnerable herbivores are preyed upon by large numbers of aggressive ants. However, even under these conditions, enhancement of plant fitness is not inevitable. This raises the question of why extrafloral nectaries have been retained in a plant that is as successful and widespread as bracken.
- Full Text:
- Authors: Rashbrook, Vanessa Karin
- Date: 1989
- Subjects: Arthropod pests -- South Africa Ants -- South Africa Ferns -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5592 , http://hdl.handle.net/10962/d1002042
- Description: Bracken (Pteridium aquilinum) is a cosmopolitan species of fern which possesses extrafloral nectaries. A survey of the arthropod fauna associated with the plant throughout its range in South Africa identified the most widespread and damaging bracken herbivores and those species most likely to be influenced by ants visiting the extrafloral nectaries. Seventeen herbivorous arthropods were found to be definitely feeding on bracken and a further thirteen species with a less certain status were recorded. In addition, several species of ants were observed on the fronds and feeding at the extrafloral nectarie. On the basis of their widespread distribution and abundance, four bracken herbivores emerged as being particularly detrimental to the plant in South Africa. They were an eriophyid gall mite, a leafhopper and two moths. The biology of the two lepidopterans, Appana cinisigna and Panotima sp., suggested that they were potentially vulnerable to ants at various stages of their life histories. Laboratory experiments were undertaken to observe ant-lepidopteran interactions under controlled conditions. The ant Crematogaster peringueyi rapidly removed exposed A. cini igna eggs, but did not appear to regard Panotima eggs as food items. Small instar larvae of both species proved vulnerable, but the larger larvae appeared capable of escaping ant predation. Ant exclusion experiments in the field, using natural and artificially augmented ant densities, were carried out at two sites near Grahamstown. The dominant ant species was C. peringueyi. Neither the numbers of lepidopterans nor levels of herbivory were significantly reduced by the presence of ants . Despite the implications of the laboratory tests, the results of these field experiments did not support the hypothesis that ants which visit bracken extrafloral nectaries benefit the plant. Ant-bracken field studies on other continents also reported no significant ant-related effects, though marginal reductions in the abundance of certain herbivores have been noted at one site in the U.K. Since ant protection does not appear to be an inevitable consequence of having extrafloral nectaries, their value to bracken is in some doubt. The most likely situation where effective protection will occur is when high densities of vulnerable herbivores are preyed upon by large numbers of aggressive ants. However, even under these conditions, enhancement of plant fitness is not inevitable. This raises the question of why extrafloral nectaries have been retained in a plant that is as successful and widespread as bracken.
- Full Text:
Investigation of the causative agents of the 1982 Gazankulu poliomyelitis outbreak, using four biochemical techniques
- Authors: Gibson, Katherine Margaret
- Date: 1989
- Subjects: Poliomyelitis -- Analysis , Poliomyelitis -- History -- South Africa , Poliomyelitis vaccine -- Analysis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3878 , http://hdl.handle.net/10962/d1001612
- Description: Comparison of poliovirus strains was carried out to determine the origin of the virus in two isolates obtained during the 1982 outbreak of poliomyelitis in Gazankulu. Comparisons of the outbreak isolates with vaccine and wild-type strains of the same poliovirus type were carried out using four biochemical techniques. SDS-polyacrylamide gel electrophoresis (SDS-PAGE), two-dimensional thin-layer chromatography (TLC) and reversed-phase high-performance liquid-chromatography (RP-HPLC) were used for comparing viral capsid proteins. Comparison of poliovirus strains at a genetic level was carried out using two-dimensional oligonucleotide mapping of viral RNA. Results showed the type 1 poliovirus isolate, 5061, to be a novel wild-type poliovirus. The type 2 isolate, 5068, was closely related to the poliovirus type 2 Sabin vaccine strain, P712. It was concluded that the intrinsic variability of poliovirus strains was responsible for the appearance of isolate 5068
- Full Text:
- Authors: Gibson, Katherine Margaret
- Date: 1989
- Subjects: Poliomyelitis -- Analysis , Poliomyelitis -- History -- South Africa , Poliomyelitis vaccine -- Analysis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3878 , http://hdl.handle.net/10962/d1001612
- Description: Comparison of poliovirus strains was carried out to determine the origin of the virus in two isolates obtained during the 1982 outbreak of poliomyelitis in Gazankulu. Comparisons of the outbreak isolates with vaccine and wild-type strains of the same poliovirus type were carried out using four biochemical techniques. SDS-polyacrylamide gel electrophoresis (SDS-PAGE), two-dimensional thin-layer chromatography (TLC) and reversed-phase high-performance liquid-chromatography (RP-HPLC) were used for comparing viral capsid proteins. Comparison of poliovirus strains at a genetic level was carried out using two-dimensional oligonucleotide mapping of viral RNA. Results showed the type 1 poliovirus isolate, 5061, to be a novel wild-type poliovirus. The type 2 isolate, 5068, was closely related to the poliovirus type 2 Sabin vaccine strain, P712. It was concluded that the intrinsic variability of poliovirus strains was responsible for the appearance of isolate 5068
- Full Text:
Isolation, purification and effect of ligands on the nicotinic cholinergic receptor
- Authors: Kapp, Eugene Anthony
- Date: 1989
- Subjects: Ligands (Biochemistry) , Nicotinic receptors
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4550 , http://hdl.handle.net/10962/d1018235
- Description: The nicotinic cholinergic receptor protein of the fish electric organ, Torpedo fuscomaculata, has been isolated, purified and shown to represent a true model for the nAChR from other species and higher vertebrates. It is an integral membrane protein composed of four different subunits, tightly associated with other functional, but non-specific proteins. Purification of the nicotinic cholinergic receptor by chromatofocusing demonstrates an improved method over that of affinity and ion-exchange chromatography. Gel chromatography and SDS-polyacrylamide gel electrophoresis show evidence of four subunits; a(40-44 kDa), 6(53 kDa ),'Y(63 kDa) and 6(66 kDa) despite some degradation of receptor molecules by intracellular proteases. Spectrophotometric and fluorimetric studies of receptor-ligand interactions, show the functional and chemical integrity of the receptor to remain intact after solubilisation. The effect of cholinergic ligands on purified receptor preparations indicate quenching of the intrinsic fluorescence of the receptor. Agonists, like acetylcholine, bind and cause local conformational transitions, changing the active region from a hydrophobic to a hydrophilic environment. This phenomenon is illustrated by the 10-fold increase in fluorescence when the receptor is in a desensitised state. Antagonists, such as d-Tubocurarine, block this conformational transition. In vitro rectus abdominis muscle preparations . show the nitrosamines, dimethylnitrosamine and diphenylnitrosamine, to be true agonists of the nAChR. However their low affinity and specificity for the receptor precludes them as photoaffmity labelling agents. Photoactivation of dimethylnitrosamine occurs when associated with an acidic hydrogen at the active site of the receptor, suggesting energy-transfer labelling to be more facile than photoaffmity labelling. The membrane-bound receptor, in the presence of these nitrosamines, undergoes conformational transitions regulating the opening and closing of the ion-channel. Desensitisation and receptor activation are shown to involve one and the same molecular transition.
- Full Text:
- Authors: Kapp, Eugene Anthony
- Date: 1989
- Subjects: Ligands (Biochemistry) , Nicotinic receptors
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4550 , http://hdl.handle.net/10962/d1018235
- Description: The nicotinic cholinergic receptor protein of the fish electric organ, Torpedo fuscomaculata, has been isolated, purified and shown to represent a true model for the nAChR from other species and higher vertebrates. It is an integral membrane protein composed of four different subunits, tightly associated with other functional, but non-specific proteins. Purification of the nicotinic cholinergic receptor by chromatofocusing demonstrates an improved method over that of affinity and ion-exchange chromatography. Gel chromatography and SDS-polyacrylamide gel electrophoresis show evidence of four subunits; a(40-44 kDa), 6(53 kDa ),'Y(63 kDa) and 6(66 kDa) despite some degradation of receptor molecules by intracellular proteases. Spectrophotometric and fluorimetric studies of receptor-ligand interactions, show the functional and chemical integrity of the receptor to remain intact after solubilisation. The effect of cholinergic ligands on purified receptor preparations indicate quenching of the intrinsic fluorescence of the receptor. Agonists, like acetylcholine, bind and cause local conformational transitions, changing the active region from a hydrophobic to a hydrophilic environment. This phenomenon is illustrated by the 10-fold increase in fluorescence when the receptor is in a desensitised state. Antagonists, such as d-Tubocurarine, block this conformational transition. In vitro rectus abdominis muscle preparations . show the nitrosamines, dimethylnitrosamine and diphenylnitrosamine, to be true agonists of the nAChR. However their low affinity and specificity for the receptor precludes them as photoaffmity labelling agents. Photoactivation of dimethylnitrosamine occurs when associated with an acidic hydrogen at the active site of the receptor, suggesting energy-transfer labelling to be more facile than photoaffmity labelling. The membrane-bound receptor, in the presence of these nitrosamines, undergoes conformational transitions regulating the opening and closing of the ion-channel. Desensitisation and receptor activation are shown to involve one and the same molecular transition.
- Full Text:
Jean Dubuffet : a study of his concepts pertaining to the alienation of the artist
- Authors: Mather-Pike, Richard
- Date: 1989
- Language: English
- Type: Thesis , Masters , MFA
- Identifier: vital:21086 , http://hdl.handle.net/10962/6290
- Description: I decided on an investigation into the nature of Dubuffet's remarks concerning the plight of the artist in modern societies, believing that the difficulties facing the artist are, at the time of this writing, still in force, and perhaps even more so now than they were in his day. These difficulties I believe, arise in the form of curtailments on personal and aesthetic freedoms brought about as the result of the artist's position in, and conformity to, the norms and values of his society. The problem is I believe, that these value systems not only censor or curb artistic freedom but actually restrict all individual enterprises by demanding that the indi vidual conform to the greater wish of the group, at the expense of his own creative and individual potential.
- Full Text:
- Authors: Mather-Pike, Richard
- Date: 1989
- Language: English
- Type: Thesis , Masters , MFA
- Identifier: vital:21086 , http://hdl.handle.net/10962/6290
- Description: I decided on an investigation into the nature of Dubuffet's remarks concerning the plight of the artist in modern societies, believing that the difficulties facing the artist are, at the time of this writing, still in force, and perhaps even more so now than they were in his day. These difficulties I believe, arise in the form of curtailments on personal and aesthetic freedoms brought about as the result of the artist's position in, and conformity to, the norms and values of his society. The problem is I believe, that these value systems not only censor or curb artistic freedom but actually restrict all individual enterprises by demanding that the indi vidual conform to the greater wish of the group, at the expense of his own creative and individual potential.
- Full Text:
Local government restructuring : white municipal initiatives 1985-1988
- Authors: Atkinson, Doreen
- Date: 1989
- Subjects: Local government -- South Africa Municipal government -- South Africa
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/d1011618 , vital:20235 , ISBN 0868101826
- Description: The local government level has historically been the most neglected aspect of government in South Africa, both in research and in conventional political activity. Yet, paradoxically, it has been the level at which several crucial government policies have played themselves out, away from the public eye, but drastic in their effects on the material and political position of all inhabitants of towns and cities in South Africa. This research into local government was begun with two basic questions in mind. Firstly, local-level attempts to alter their own institutional structures needed to be documented and analysed. A consideration of six case studies of white initiatives for change at the local level uncovered numerous political and economic dimensions which interact and set constraints on each other. It is impossible to produce one final interpretation of why these local events happened, what their significance was, and what possibilities they offer for the future. Invariably, each case study is a microcosm of the broader multifaceted conflict in South Africa. This report is an attempt to present as many of these dimensions as possible, even though it cannot ever be complete. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Authors: Atkinson, Doreen
- Date: 1989
- Subjects: Local government -- South Africa Municipal government -- South Africa
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/d1011618 , vital:20235 , ISBN 0868101826
- Description: The local government level has historically been the most neglected aspect of government in South Africa, both in research and in conventional political activity. Yet, paradoxically, it has been the level at which several crucial government policies have played themselves out, away from the public eye, but drastic in their effects on the material and political position of all inhabitants of towns and cities in South Africa. This research into local government was begun with two basic questions in mind. Firstly, local-level attempts to alter their own institutional structures needed to be documented and analysed. A consideration of six case studies of white initiatives for change at the local level uncovered numerous political and economic dimensions which interact and set constraints on each other. It is impossible to produce one final interpretation of why these local events happened, what their significance was, and what possibilities they offer for the future. Invariably, each case study is a microcosm of the broader multifaceted conflict in South Africa. This report is an attempt to present as many of these dimensions as possible, even though it cannot ever be complete. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
Lola Watter, Images from Africa. Johannesburg Justified Press. 19~
- Authors: Butler, Frederick Guy
- Date: 1989
- Subjects: To be catalogued
- Language: English
- Type: text , poem
- Identifier: http://hdl.handle.net/10962/469039 , vital:77152 , ISBN 0028-4459 , https://journals.co.za/doi/epdf/10.10520/AJA00284459_208
- Description: New Coin is one of South Africa's most established and influential poetry journals. It publishes poetry, and poetry-related reviews, commentary and interviews. New Coin places a particular emphasis on evolving forms and experimental use of the English language in poetry in the South African context. In this sense it has traced the most exciting trends and currents in contemporary poetry in South Africa for a decade of more. The journal is published twice a year in June and December by the Institute for the Study of English in Africa (ISEA), Rhodes University.
- Full Text:
- Authors: Butler, Frederick Guy
- Date: 1989
- Subjects: To be catalogued
- Language: English
- Type: text , poem
- Identifier: http://hdl.handle.net/10962/469039 , vital:77152 , ISBN 0028-4459 , https://journals.co.za/doi/epdf/10.10520/AJA00284459_208
- Description: New Coin is one of South Africa's most established and influential poetry journals. It publishes poetry, and poetry-related reviews, commentary and interviews. New Coin places a particular emphasis on evolving forms and experimental use of the English language in poetry in the South African context. In this sense it has traced the most exciting trends and currents in contemporary poetry in South Africa for a decade of more. The journal is published twice a year in June and December by the Institute for the Study of English in Africa (ISEA), Rhodes University.
- Full Text:
Medical schemes for workers
- Trade Union Research Project (TURP)
- Authors: Trade Union Research Project (TURP)
- Date: 1989
- Subjects: TURP
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/169044 , vital:41678
- Description: Medical insurance schemes have become one of 111 the many fringe benefits being negotiated by unions. Medical insurance schemes are tied to the struggle for an adequate health service. Workers’ decision on whether or not to join medical insurance schemes has an important bearing on the operation of health services in a future democratic society. This booklet examines medical aid schemes, their advantages and disadvantages, how they operate and what possible alternatives to medical aid schemes exist. The booklet also looks at the state’s health strategy and how medical aid schemes fit into this. Chapter One of this booklet discusses the broad issues relating to medical insurance. Medical Aid Schemes and Medical Benefit Schemes are discussed in chapters two and three. Chapters four and five are for extra information. Some specific medical aid schemes are evaluated in chapter four. Chapter five looks at the tariff structure (cost) of medical services provided at Natal Provincial Hospitals. Medical Insurance means all the different types of schemes that operate to insure people against medical costs. A medical insurance could take the form of a medical aid scheme, a medical benefit scheme or other types of schemes. This-booklet concentrates on medical aid and medical benefit schemes.
- Full Text:
- Authors: Trade Union Research Project (TURP)
- Date: 1989
- Subjects: TURP
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/169044 , vital:41678
- Description: Medical insurance schemes have become one of 111 the many fringe benefits being negotiated by unions. Medical insurance schemes are tied to the struggle for an adequate health service. Workers’ decision on whether or not to join medical insurance schemes has an important bearing on the operation of health services in a future democratic society. This booklet examines medical aid schemes, their advantages and disadvantages, how they operate and what possible alternatives to medical aid schemes exist. The booklet also looks at the state’s health strategy and how medical aid schemes fit into this. Chapter One of this booklet discusses the broad issues relating to medical insurance. Medical Aid Schemes and Medical Benefit Schemes are discussed in chapters two and three. Chapters four and five are for extra information. Some specific medical aid schemes are evaluated in chapter four. Chapter five looks at the tariff structure (cost) of medical services provided at Natal Provincial Hospitals. Medical Insurance means all the different types of schemes that operate to insure people against medical costs. A medical insurance could take the form of a medical aid scheme, a medical benefit scheme or other types of schemes. This-booklet concentrates on medical aid and medical benefit schemes.
- Full Text:
Mother-son enmeshment and its implications for the emancipation-individuation process: a case study study
- Gijana, Eucliffe Wycliffe Mphumzi
- Authors: Gijana, Eucliffe Wycliffe Mphumzi
- Date: 1989
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:21173 , http://hdl.handle.net/10962/6728
- Description: This case study reports on a patient who was undergoing psychotherapy for an Adjustment Disorder with Mixed Emotional Features. The aim of the study had two aspects. First the study sought to establish to what degree was enmeshment between the patient and his mother responsible for his maladaptive behaviour. The second aspect was to establish the extent to which the patient responded to psychotherapy. The patient was a 20 year old male university student. He was experiencing a number of problems including difficulty in interpersonal relations, deteriorating academic performance, depression, anxiety and uncertainty about career choice and about the future. The history revealed that the patient had very close and enmeshed relations with his mother. The mother was a very domineering person and had great influence on her son. On the other hand his father was weak and emotionally unavailable. The patient had never been away from home until after he graduated from High School and decided to join the army. It was then his problem began to manifest. He left the army and registered at university. However, the problems continued and even increased in intensity. It was hypothesized that as a result of enmeshment with his mother and the fact that his mother was a domineering personality, he never had the opportunity to learn social skills that would have enabled him to emancipate himself from his mother . Thus when he moved out of home to be on his own, first in the army and later at university, he could not cope. He lost self-confidence, became passive, indecisive and dependent. Psychotherapy was successful in helping him gain insight into the genesis of his problem. This insight resulted in the patient's efforts towards individuation.
- Full Text:
- Authors: Gijana, Eucliffe Wycliffe Mphumzi
- Date: 1989
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:21173 , http://hdl.handle.net/10962/6728
- Description: This case study reports on a patient who was undergoing psychotherapy for an Adjustment Disorder with Mixed Emotional Features. The aim of the study had two aspects. First the study sought to establish to what degree was enmeshment between the patient and his mother responsible for his maladaptive behaviour. The second aspect was to establish the extent to which the patient responded to psychotherapy. The patient was a 20 year old male university student. He was experiencing a number of problems including difficulty in interpersonal relations, deteriorating academic performance, depression, anxiety and uncertainty about career choice and about the future. The history revealed that the patient had very close and enmeshed relations with his mother. The mother was a very domineering person and had great influence on her son. On the other hand his father was weak and emotionally unavailable. The patient had never been away from home until after he graduated from High School and decided to join the army. It was then his problem began to manifest. He left the army and registered at university. However, the problems continued and even increased in intensity. It was hypothesized that as a result of enmeshment with his mother and the fact that his mother was a domineering personality, he never had the opportunity to learn social skills that would have enabled him to emancipate himself from his mother . Thus when he moved out of home to be on his own, first in the army and later at university, he could not cope. He lost self-confidence, became passive, indecisive and dependent. Psychotherapy was successful in helping him gain insight into the genesis of his problem. This insight resulted in the patient's efforts towards individuation.
- Full Text:
Namibia freedom rally
- Namibia Solidarity Committee
- Authors: Namibia Solidarity Committee
- Date: 1989
- Subjects: Namibia Solidarity Committee
- Language: English,Xhosa,Afrikaans
- Type: text
- Identifier: http://hdl.handle.net/10962/154220 , vital:39622
- Description: Die mense van Namibia het uiteindelik hul vryheid gekry! Hulle het getriomf teenoor die koloniale regering in Pretoria en die brutale apartheid magte. Die mense van Namibia sal binnekort hulle self kan begin regeer. Hulle sal ’n nuwe nasie bou - vry van onderdmkking en uitbuiting.
- Full Text:
- Authors: Namibia Solidarity Committee
- Date: 1989
- Subjects: Namibia Solidarity Committee
- Language: English,Xhosa,Afrikaans
- Type: text
- Identifier: http://hdl.handle.net/10962/154220 , vital:39622
- Description: Die mense van Namibia het uiteindelik hul vryheid gekry! Hulle het getriomf teenoor die koloniale regering in Pretoria en die brutale apartheid magte. Die mense van Namibia sal binnekort hulle self kan begin regeer. Hulle sal ’n nuwe nasie bou - vry van onderdmkking en uitbuiting.
- Full Text:
Nesting of sympatric redwinged and pale winged starlings
- Craig, Adrian J F K, Hulley, Patrick E, Walter, Grenville H
- Authors: Craig, Adrian J F K , Hulley, Patrick E , Walter, Grenville H
- Date: 1989
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/447827 , vital:74677 , https://doi.org/10.1080/00306525.1989.9634513
- Description: Observations were made over four breeding seasons at Cradock, South Africa, where Redwinged Starlings Onychognathus morio and Palewinged Starlings O. nabouroup nest on the same cliffs. Nests were not accessible, and the stage of breeding was determined by the behaviour of the birds. Both species reuse the same nest sites, and only the females incubate, but both sexes feed the young. The timing of breedingMaybe more variable in the Palewinged Starling. A review of the available data on nest site selection and nest construction shows apparent species-specific differences: Redwinged Starlings usually nest on ledges, often on buildings, and use mud in the nest base; Palewinged Starlings favour vertical crevices, and do not use mud.
- Full Text:
- Authors: Craig, Adrian J F K , Hulley, Patrick E , Walter, Grenville H
- Date: 1989
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/447827 , vital:74677 , https://doi.org/10.1080/00306525.1989.9634513
- Description: Observations were made over four breeding seasons at Cradock, South Africa, where Redwinged Starlings Onychognathus morio and Palewinged Starlings O. nabouroup nest on the same cliffs. Nests were not accessible, and the stage of breeding was determined by the behaviour of the birds. Both species reuse the same nest sites, and only the females incubate, but both sexes feed the young. The timing of breedingMaybe more variable in the Palewinged Starling. A review of the available data on nest site selection and nest construction shows apparent species-specific differences: Redwinged Starlings usually nest on ledges, often on buildings, and use mud in the nest base; Palewinged Starlings favour vertical crevices, and do not use mud.
- Full Text:
NUM Biennial report
- NUM
- Authors: NUM
- Date: 1989
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/149589 , vital:38866
- Description: Since the Fifth National Congress in 1987 where our union adopted the Freedom Charter and charted a clear political direction for the NUM, many gallant battles have been waged by the mineworkers on many fronts. 1987 was the year in which our union launched its campaign to effect control of miners working lives. It was a year when mineworkers took control indeed in keeping with the Fifth Congress Slogan -"1987 THE YEAR MINEWORKERS TAKE CONTROL", as many comrades began to take over the hostels, particularly in the Witbank Region which resulted in families moving into the hostels for a period of time. Although the process remained uneven, the initiative was an important indicator of the willingness of the workers to take action and implement resolutions adopted by our union. In spite of the existence of the State of Emergency, the dedication, commitment, spirit and enthusiasm of mineworkers remained high. 1987 was also the year in which the NUM made its mark on the mining industry with the historic Great Miners Strike. This action, involving over 340 000 workers was the biggest of its kind in South African Labour History, and also the biggest action by workers of its kind on the African continent. We challenged some of the fundamental policies of the mining industry, in particular, the concept of poverty wages which has become one of the major battle grounds for our union. Despite mass dismissals of 50 000 workers, our union has remained and continues to mobilise and organise mineworkers against the oppressive and exploitative conditions. 1987 will certainly go down in history as the year of mass action by mineworkers throughout South Africa. It is well known that the strike did affect our organisation in many areas. Actions by management to roll back the gains of our union continued unabated after the strike right through until now.
- Full Text:
- Authors: NUM
- Date: 1989
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/149589 , vital:38866
- Description: Since the Fifth National Congress in 1987 where our union adopted the Freedom Charter and charted a clear political direction for the NUM, many gallant battles have been waged by the mineworkers on many fronts. 1987 was the year in which our union launched its campaign to effect control of miners working lives. It was a year when mineworkers took control indeed in keeping with the Fifth Congress Slogan -"1987 THE YEAR MINEWORKERS TAKE CONTROL", as many comrades began to take over the hostels, particularly in the Witbank Region which resulted in families moving into the hostels for a period of time. Although the process remained uneven, the initiative was an important indicator of the willingness of the workers to take action and implement resolutions adopted by our union. In spite of the existence of the State of Emergency, the dedication, commitment, spirit and enthusiasm of mineworkers remained high. 1987 was also the year in which the NUM made its mark on the mining industry with the historic Great Miners Strike. This action, involving over 340 000 workers was the biggest of its kind in South African Labour History, and also the biggest action by workers of its kind on the African continent. We challenged some of the fundamental policies of the mining industry, in particular, the concept of poverty wages which has become one of the major battle grounds for our union. Despite mass dismissals of 50 000 workers, our union has remained and continues to mobilise and organise mineworkers against the oppressive and exploitative conditions. 1987 will certainly go down in history as the year of mass action by mineworkers throughout South Africa. It is well known that the strike did affect our organisation in many areas. Actions by management to roll back the gains of our union continued unabated after the strike right through until now.
- Full Text:
Obedient daughter, silenced witch: the hysteric in Freudian psychoanalysis
- Authors: Roux, Catharina
- Date: 1989
- Subjects: Freud, Sigmund, 1856-1939 -- Criticism and interpretation , Hysteria , Psychoanalysis , Seduction
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3117 , http://hdl.handle.net/10962/d1004637 , Freud, Sigmund, 1856-1939 -- Criticism and interpretation , Hysteria , Psychoanalysis , Seduction
- Description: This study explores the theoretical consequences of Freud's renunciation of the seduction theory. The dissertation defends the thesis that the seduction theory was shaped as much by Freud's adherence to the nomonological model as by the empirical evidence of child sexual abuse. A renunciation of the seduction theory was inevitable, not because the accounts of the daughters were lies, but because the methodology was inappropriate. The nomonological model obscured the emotional structure of the nuclear family in which the structure itself, through which sexuality emerged, directed the girl's entrance into womanhood and caused the woman's dis-ease. Freud's methodology forced him to isolate an event as cause of an illness and to attribute the event to an agent. The universal perversity of the Victorian father thus became the central theme around which an explanation of a female disease was built. When this theme became theoretically untenable, Freud renounced the seduction theory and, still using the nomonological model, built up the construct of the Oedipus complex in which the father was vindicated. In order to exonerate the father, the transactions through which the child's libido developed were represented as originating in inherent tendencies. As a result, the hierarchical nature of the interaction between parent and child was distorted, and this led to the formulation of the distinction between real events and fantasies as a basic premise on which the difference between the pleasure principle and the reality principle rests. This formulation gave rise to the sharp duality between fantasy and reality which eventually compelled him to separate psychic reality and social reality. The theoretical structure built on this duality could not but fuse hysteria, masochism and "normal" femininity into an explanation of the female state, and obscure the essential social relations between men and women which were structured in terms of dominance and submission. The thesis traces the journey from the perverted father as cause of a female disease, hysteria, to the theoretical conjunction of masochism and hysteria. It comes to the conclusion that Freud's model is unable to explain the self-mutilation of the hysteric; nor is it capable of explaining the hysteric's refusal to participate in the circuit of symbolic exchanges which constituted Victorian society. The study further attempts to understand hysteria in terms of the complex interlacing of fact and fantasy and tries to show that fantasy was rooted in the facts of Victorian culture.
- Full Text:
- Authors: Roux, Catharina
- Date: 1989
- Subjects: Freud, Sigmund, 1856-1939 -- Criticism and interpretation , Hysteria , Psychoanalysis , Seduction
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3117 , http://hdl.handle.net/10962/d1004637 , Freud, Sigmund, 1856-1939 -- Criticism and interpretation , Hysteria , Psychoanalysis , Seduction
- Description: This study explores the theoretical consequences of Freud's renunciation of the seduction theory. The dissertation defends the thesis that the seduction theory was shaped as much by Freud's adherence to the nomonological model as by the empirical evidence of child sexual abuse. A renunciation of the seduction theory was inevitable, not because the accounts of the daughters were lies, but because the methodology was inappropriate. The nomonological model obscured the emotional structure of the nuclear family in which the structure itself, through which sexuality emerged, directed the girl's entrance into womanhood and caused the woman's dis-ease. Freud's methodology forced him to isolate an event as cause of an illness and to attribute the event to an agent. The universal perversity of the Victorian father thus became the central theme around which an explanation of a female disease was built. When this theme became theoretically untenable, Freud renounced the seduction theory and, still using the nomonological model, built up the construct of the Oedipus complex in which the father was vindicated. In order to exonerate the father, the transactions through which the child's libido developed were represented as originating in inherent tendencies. As a result, the hierarchical nature of the interaction between parent and child was distorted, and this led to the formulation of the distinction between real events and fantasies as a basic premise on which the difference between the pleasure principle and the reality principle rests. This formulation gave rise to the sharp duality between fantasy and reality which eventually compelled him to separate psychic reality and social reality. The theoretical structure built on this duality could not but fuse hysteria, masochism and "normal" femininity into an explanation of the female state, and obscure the essential social relations between men and women which were structured in terms of dominance and submission. The thesis traces the journey from the perverted father as cause of a female disease, hysteria, to the theoretical conjunction of masochism and hysteria. It comes to the conclusion that Freud's model is unable to explain the self-mutilation of the hysteric; nor is it capable of explaining the hysteric's refusal to participate in the circuit of symbolic exchanges which constituted Victorian society. The study further attempts to understand hysteria in terms of the complex interlacing of fact and fantasy and tries to show that fantasy was rooted in the facts of Victorian culture.
- Full Text:
Op hom die groot hosannas : enkele aspekte van die modern Christelike poësie in Afrikaans
- Authors: Bosman, Maria Elizabeth
- Date: 1989
- Subjects: Afrikaans poetry -- History and criticism , Religious poetry, Afrikaans -- History and criticism , Christian poetry, Afrikaans , Calvinism in literature , Blum, Peter, 1925-1990 , Rousseau, Ina , Cussons, Sheila , De Villiers, I. L., 1936-2009 , Cloete, T. T. (Theunis Theodorus), 1924-2015 , Spies, Lina , Müller, Petra, 1935-
- Language: Afrikaans
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3566 , http://hdl.handle.net/10962/d1002089 , Afrikaans poetry -- History and criticism , Religious poetry, Afrikaans -- History and criticism
- Description: This study is concerned with modern Christian poetry in Afrikaans. Afrikaans poetry, which initially carried the clear stamp of the Afrikaner's Calvinistic view of life, gradually assumed a new image to the extent that it could no longer be recognised as religious and specifically Calvinistic poetry. To the contrary, modern Afrikaans Christian poetry is the expression of a contemporary conceptualisation of the very same gospel. The occasional violent reaction especially of conservative institutions to so called "unchristian" modern poetry in Afrikaans during the past three decades, has prompted this study which attempts to illustrate that modern Afrikaans poetry still exhibits a strong Christian element. The essential qualities of contemporary Christian poetry in Afrikaans are illustrated in the discussion of the works of particular leading Afrikaans poets. Chapter 3 attempts to indicate a transitional stage between traditional and modern Christian poetry by means of an overview of the latest tendencies and approaches, with brief references to the recent poetry of the Louws, the poetry of Peter Blum as the initial exponent of the poetry of the Sixties, and the poetry of Ina Rousseau. The work of Sheila Cussons, eminent Roman Catholic (and thus also Christian) poet who is probably the most impressive contemporary exponent of metaphysical/mystic poetry in Afrikaans, is discussed in chapter 4. Chapter 5 illustrates the traditional Calvinistic Christian point of view and Christian experience as represented in the poetry of I.L. de Villiers. The poetification of the ministry adds new dimension to religions poetry in Afrikaans. Chapter 6 constitutes a discussion of the works of T.T . Cloete, the most significant contemporary Reformed poet in Afrikaans indicating the extent to which the many related facets embodied in his poetry consistently reflect a Christian attitude and are unified in and encompassed by the principle of Soli Deo Gloria. Chapter 7, by way of conclusion, reviews the religious poetry of Lina Spies and Petra Müller who write accessible popular poetry, nevertheless exploring interesting references. In conjunction with the poetry of Ina Rosseau, this poetry represents a contribution to modern Afrikaans religious poetry from a feminine point of view
- Full Text:
- Authors: Bosman, Maria Elizabeth
- Date: 1989
- Subjects: Afrikaans poetry -- History and criticism , Religious poetry, Afrikaans -- History and criticism , Christian poetry, Afrikaans , Calvinism in literature , Blum, Peter, 1925-1990 , Rousseau, Ina , Cussons, Sheila , De Villiers, I. L., 1936-2009 , Cloete, T. T. (Theunis Theodorus), 1924-2015 , Spies, Lina , Müller, Petra, 1935-
- Language: Afrikaans
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3566 , http://hdl.handle.net/10962/d1002089 , Afrikaans poetry -- History and criticism , Religious poetry, Afrikaans -- History and criticism
- Description: This study is concerned with modern Christian poetry in Afrikaans. Afrikaans poetry, which initially carried the clear stamp of the Afrikaner's Calvinistic view of life, gradually assumed a new image to the extent that it could no longer be recognised as religious and specifically Calvinistic poetry. To the contrary, modern Afrikaans Christian poetry is the expression of a contemporary conceptualisation of the very same gospel. The occasional violent reaction especially of conservative institutions to so called "unchristian" modern poetry in Afrikaans during the past three decades, has prompted this study which attempts to illustrate that modern Afrikaans poetry still exhibits a strong Christian element. The essential qualities of contemporary Christian poetry in Afrikaans are illustrated in the discussion of the works of particular leading Afrikaans poets. Chapter 3 attempts to indicate a transitional stage between traditional and modern Christian poetry by means of an overview of the latest tendencies and approaches, with brief references to the recent poetry of the Louws, the poetry of Peter Blum as the initial exponent of the poetry of the Sixties, and the poetry of Ina Rousseau. The work of Sheila Cussons, eminent Roman Catholic (and thus also Christian) poet who is probably the most impressive contemporary exponent of metaphysical/mystic poetry in Afrikaans, is discussed in chapter 4. Chapter 5 illustrates the traditional Calvinistic Christian point of view and Christian experience as represented in the poetry of I.L. de Villiers. The poetification of the ministry adds new dimension to religions poetry in Afrikaans. Chapter 6 constitutes a discussion of the works of T.T . Cloete, the most significant contemporary Reformed poet in Afrikaans indicating the extent to which the many related facets embodied in his poetry consistently reflect a Christian attitude and are unified in and encompassed by the principle of Soli Deo Gloria. Chapter 7, by way of conclusion, reviews the religious poetry of Lina Spies and Petra Müller who write accessible popular poetry, nevertheless exploring interesting references. In conjunction with the poetry of Ina Rosseau, this poetry represents a contribution to modern Afrikaans religious poetry from a feminine point of view
- Full Text:
Opening our eyes
- Cape Educational Computer Society (CECS)
- Authors: Cape Educational Computer Society (CECS)
- Date: 1989
- Subjects: Cape Educational Computer Society (CECS)
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/250511 , vital:52008
- Description: This is a bold statement and a difficult one for people who regard] computers as a tool of the rich. Yes the computer is a tool or the rich. But more and more of these weird little machines are finding their way into our backyards and ghettos, into the backrooms of our community organisations and even into our classrooms. Each of these computers can do what only the rich with million rand typographic equipment could do 10 years ago . Today ordinary people can bring out media of a quality that only highly trained professionals using specialised equipment used to be able to produce. This edition of CECS NEWS is proof of this. Almost the entire newsletter was produced by High School student members of CECS trained on a 5-day camp in June. “Computers For All” is not just an empty slogan but a possible reality. We decided at the camp to devote an entire issue to just this topic: Media on Computers.
- Full Text:
- Authors: Cape Educational Computer Society (CECS)
- Date: 1989
- Subjects: Cape Educational Computer Society (CECS)
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/250511 , vital:52008
- Description: This is a bold statement and a difficult one for people who regard] computers as a tool of the rich. Yes the computer is a tool or the rich. But more and more of these weird little machines are finding their way into our backyards and ghettos, into the backrooms of our community organisations and even into our classrooms. Each of these computers can do what only the rich with million rand typographic equipment could do 10 years ago . Today ordinary people can bring out media of a quality that only highly trained professionals using specialised equipment used to be able to produce. This edition of CECS NEWS is proof of this. Almost the entire newsletter was produced by High School student members of CECS trained on a 5-day camp in June. “Computers For All” is not just an empty slogan but a possible reality. We decided at the camp to devote an entire issue to just this topic: Media on Computers.
- Full Text:
Operating in turbulent times: an investigation into the characteristics of strategic flexibility exhibited by South African export companies
- Authors: Skae, Frederick Owen
- Date: 1989
- Subjects: Export trading companies -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1159 , http://hdl.handle.net/10962/d1001626
- Description: Broadly stated, the major objective of this study was to investigate the extent to which South African export companies exhibited characteristics of strategic flexibility, which is seen to be the most viable strategic option for a firm operating within a turbulent environment. This entailed:- (1) Determining the degree of environmental turbulence as perceived by South African export companies and identifying the most important elements of the external environment as perceived by these companies. (2) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies facing environments of either low, medium or high turbulence. (3) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies of different size. In order to elicit this information, 1361 questionnaires were posted to the managing directors of export firms who were members of the South African Foreign Trade Organization. The major findings of this study indicate that:- (1) Political elements of the remote environment contribute most to environmental turbulence. (2) Respondents identified economic elements as being the most important in terms of their potential impact on the long term profitability of the firm. (3) Although at present the majority of the firms surveyed were classified as operatIng in medium levels of turbulence, in the future they perceive the external environment as becoming very turbulent. (4) Generally speaking, the firms surveyed are ill-equipped to operate in a turbulent environment as they displayed signs of inflexibility in certain key aspects of their business. In this regard, particular mention must be made of their decision-making processes, the extent to which they had specialist planners, the techniques used to identify future trends in the environment, the extent to which computer technology was utilised in the firm and their structure. (5) Finally, the results do not generally support the view that a relationship exists between the perceived degree of turbulence in the environment and the extent to which strategic flexibility exists in the firm. Often, however, the size of tne firm was more of a determining factor on the components of strategic flexibility than the degree of turbulence in the environment. In this regard, particular mention must be made of the impact of size on the planning processes of the firm, the techniques used to monitor trends in the environment and the emphasis placed on management development and training.
- Full Text:
- Authors: Skae, Frederick Owen
- Date: 1989
- Subjects: Export trading companies -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1159 , http://hdl.handle.net/10962/d1001626
- Description: Broadly stated, the major objective of this study was to investigate the extent to which South African export companies exhibited characteristics of strategic flexibility, which is seen to be the most viable strategic option for a firm operating within a turbulent environment. This entailed:- (1) Determining the degree of environmental turbulence as perceived by South African export companies and identifying the most important elements of the external environment as perceived by these companies. (2) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies facing environments of either low, medium or high turbulence. (3) Identifying the nature and strength of the various components of strategic flexibility possessed by South African export companies of different size. In order to elicit this information, 1361 questionnaires were posted to the managing directors of export firms who were members of the South African Foreign Trade Organization. The major findings of this study indicate that:- (1) Political elements of the remote environment contribute most to environmental turbulence. (2) Respondents identified economic elements as being the most important in terms of their potential impact on the long term profitability of the firm. (3) Although at present the majority of the firms surveyed were classified as operatIng in medium levels of turbulence, in the future they perceive the external environment as becoming very turbulent. (4) Generally speaking, the firms surveyed are ill-equipped to operate in a turbulent environment as they displayed signs of inflexibility in certain key aspects of their business. In this regard, particular mention must be made of their decision-making processes, the extent to which they had specialist planners, the techniques used to identify future trends in the environment, the extent to which computer technology was utilised in the firm and their structure. (5) Finally, the results do not generally support the view that a relationship exists between the perceived degree of turbulence in the environment and the extent to which strategic flexibility exists in the firm. Often, however, the size of tne firm was more of a determining factor on the components of strategic flexibility than the degree of turbulence in the environment. In this regard, particular mention must be made of the impact of size on the planning processes of the firm, the techniques used to monitor trends in the environment and the emphasis placed on management development and training.
- Full Text: